3,744 results on '"Carbamide Peroxide"'
Search Results
102. Non-invasive vital teeth whitening for enhanced facial esthetic: A case report.
- Author
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Chauhan, Megna, Singh, Kriti, Chauhan, Raju, Shukla, Preeti, and Misra, Pradyumna
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DENTAL discoloration ,TOOTH whitening ,COSMETIC dentistry ,INCISORS ,TOOTH sensitivity ,CARBAMIDE peroxide - Abstract
For ages, a bright white smile symbolizes beauty, wellness, and vitality. The translucency and thickness of the enamel, hue of the underlying dentin, vitality, and color of the pulp all contribute to the pigmentation of teeth. Color changes in the crown can be due to physiologic or pathologic and endogenous or exogenous factors. Extrinsic or intrinsic stains are the most common causes of tooth discoloration. Discoloration, especially in the anterior teeth, seriously impairs esthetics and might make a patient feel less confident. In the treatment of discolored teeth, various invasive and non-invasive options, such as veneers and bleaching, are available, respectively. However, the urge for esthetic dentistry, particularly teeth whitening, has grown significantly in recent decades. As compared to invasive treatment options, non-invasive methods like bleaching (teeth whitening) are the most conservative choice for stained teeth and are preferred in situations where tooth structure is intact. Teeth whitening has developed into a well-liked and commonly requested dental procedure as a result of the public need for a brighter smile and enhanced looks. This paper aims to describe a case of vital, discolored anterior teeth due to fluorosis lightened using 35% hydrogen peroxide. A 19-year-old female patient reported to the department with discolored upper front teeth. After the procedure was completed, a pleasing esthetic result was achieved. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
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103. Effectiveness of Teeth Whitening after Regenerative Endodontics Procedures: An In Vitro Study.
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Fagogeni, Irini, Metlerska, Joanna, Falgowski, Tomasz, Górski, Maciej, Lipski, Mariusz, and Nowicka, Alicja
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TOOTH whitening , *REGENERATION (Biology) , *PLATELET-rich fibrin , *DENTAL discoloration , *BLEACHING (Chemistry) , *CARBAMIDE peroxide - Abstract
Discolouration resulting from regenerative endodontic procedures may have a negative impact on the quality of life of treated patients; therefore, it is recommended to minimize this risk by selecting appropriate scaffolds and barrier materials, and if discolouration occurs, the use of a simple, cost-effective and minimally invasive technique, such as whitening, should be considered. This in vitro study aimed to evaluate tooth discolouration after two- and single-visit regenerative endodontic procedures and the effectiveness of subsequent whitening procedures with carbamide peroxide. Two hundred bovine incisors were included in this study and divided into twenty groups based on the tested material combinations. Two groups were control groups, one with saline and the other group with blood. In the 12 groups, the experiment was designed to be consistent with the two-visit regenerative endodontic procedures. Triple antibiotic paste or calcium hydroxide were placed in the root canal, and then scaffolds (e.g., blood or platelet-rich fibrin) and barrier materials (Biodentine, OrthoMTA or MTA Repair HP) were applied after rinsing the disinfectant pastes. In the six groups that corresponded to the single-visit regenerative endodontic procedure, the use of a disinfectant paste was omitted. Subsequently, the specimens were bleached twice with carbamide peroxide at a 7-day interval. Colour change measurements were performed using a spectrophotometer (VITA Easyshade Compact 5.0, VITA Zahnfabrik, Bad Säckingen, Germany). Statistical analysis was performed with the Kruskal–Wallis H test, the independent t-test and t-test for related samples. Tooth discolouration was noticed after two- and single-visit regenerative endodontic procedures, except for the platelet-rich fibrin+MTA Repair HP group. After the first and second whitening procedures, all of the tested two- and single-visit regenerative endodontic procedures groups showed a change in the colour of the crown, which was noticeable to the naked eye (∆E > 3.3). When analysing the ∆E value between the first and second bleaching procedures, no changes in the colour of teeth were visually noticed in the calcium hydroxide and platelet-rich fibrin +MTA Repair HP groups (∆E < 3.3). Single-visit regenerative endodontic procedures are suggested if possible; however, if two-visit regenerative endodontic procedures are performed, it is recommended to use calcium hydroxide as the disinfectant paste because of the lower staining potential. In the context of discolouration, platelet-rich fibrin is advisable for use as a scaffold. The whitening procedure is worth considering, but does not guarantee a return to the original tooth colour, especially when triple antibiotic paste is used. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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104. Altered physical–chemical properties of home bleaching gels after an accelerated stability study and their effects on tooth enamel.
- Author
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Sobral-Souza, Danielle Ferreira, Gouveia, Thayla Hellen Nunes, Ortiz, Mariangela Ivette Guanipa, Condeles, André Luís, Junior, José Carlos Toledo, Franz-Montan, Michelle, Aguiar, Flávio Henrique Baggio, and Lima, Débora Alves Nunes Leite
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DENTAL enamel , *CARBAMIDE peroxide , *TUKEY'S test , *HYDROGEN peroxide , *TWO-way analysis of variance - Abstract
Objectives : To investigate the physical–chemical properties of home bleaching gels based on Carbamide Peroxide (CP) and Hydrogen Peroxide (HP) after accelerated stability (AS) and its effects on enamel. Materials and Methods: A total of 360 bovine teeth blocks were divided (n = 12): Control, CP10%-Whiteness Perfect, CP10%-Pola Night, HP7.5%-Pola Day, and HP7.5%-White Class Calcium. Microhardness (KHN), roughness (Ra), color (ΔE and ΔE00), hardness, compressibility, elasticity, cohesiveness, adhesiveness, weight, pH, and calcium (Ca) quantification in enamel were analyzed without storage of the bleaching gels and after AS at 1 and 3 months. Data of Ca, KHN, and Ra were analyzed through mixed models for repeated measurements and the Tukey–Kramer test. Values of weight, hardness, compressibility, and elasticity were analyzed with two-way ANOVA and Tukey's test. ΔE/ΔE00 data, cohesiveness, and adhesiveness were analyzed with Kruskal–Wallis and Dunn tests (α = 0.05). Results: Groups subject to AS had lower ΔE and ΔE00 compared to those without storage. Lower KHN and higher Ra values were found after bleaching treatment in all groups compared to controls. Higher amounts of Ca were found on the first day of evaluation in the gels subject to AS for 3 months, regardless of the bleaching agent used. Conclusions: Incorrectly stored bleaching gel accentuates adverse effects on enamel. Temperature and humidity interfere directly with the chemical stability of bleaching agents, reducing their properties. Clinical relevance: HP is an unstable oxidizing agent when stored at high temperatures. Therefore, pH becomes more acidic and potentiates the demineralizing effect on enamel. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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105. Bleaching efficacy and quality of life of different bleaching techniques — randomized controlled trial.
- Author
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Pereira, Ruben, Silveira, João, Dias, Susana, Cardoso, Ana, Mata, António, and Marques, Duarte
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BLEACHING (Chemistry) , *TOOTH sensitivity , *CARBAMIDE peroxide , *QUALITY of life , *RANDOMIZED controlled trials , *HYDROGEN peroxide - Abstract
Objectives : To evaluate bleaching efficacy and oral health-related quality of life (ORHQoL) of three bleaching systems with similar hydrogen peroxide (HP) concentration for up to 6 months post-treatment. Materials and methods: A randomized controlled trial was designed with three parallel groups: group A — in-office 6% HP paint-on varnish; group B — at-home 6% HP with adaptable tray; group C — at-home 16% carbamide peroxide with custom tray. At three different stages (baseline, after bleaching, and 6-month follow-up), ORHQoL was evaluated by the OHIP-14 questionnaire and tooth color of the upper canines and central incisors were measured by two shade guides and a spectrophotometer (measuring CIE L*a*b* with respective color/whiteness differences − ΔE00/ΔWID). Results were presented as mean and 95% confidence intervals and statistical tests were performed appropriately, considering a significance level of α = 0.05. Results: All groups presented significant color differences (P < 0.05) between all stages, with ΔE00/ΔWID surpassing the perceptibility threshold in 98% cases, with group C's results being significantly (P < 0.05) higher when compared to other groups, although with significantly (P < 0.05) higher values of color relapse. Significative ORHQoL improvements (P < 0.05) were detected after bleaching in a global analysis with no differences between techniques. Conclusions: All techniques presented bleaching efficacy, color stability, and improvements in ORHQoL up to 6 months post-treatment. Clinical significance: Clinicians may consider both at-home and in-office bleaching techniques with 6% HP to attain long-lasting satisfactory clinical results while producing positive changes in ORHQoL. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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106. Nano‐hydroxyapatite‐induced remineralization of artificial white spot lesions after bleaching treatment with 10% carbamide peroxide.
- Author
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da Freiria, Amanda Cristina Brezolini, Ortiz, Mariangela Ivette Guanipa, de Sobral, Danielle Ferreira Souza, Aguiar, Flavio Henrique Baggio, and Lima, Débora Alves Nunes Leite
- Subjects
- *
HYDROXYAPATITE , *IN vitro studies , *REMINERALIZATION (Teeth) , *CROSS-sectional method , *COSMETIC dentistry , *PEROXIDES , *PRE-tests & post-tests , *TREATMENT effectiveness , *TOOTH whitening , *DESCRIPTIVE statistics - Abstract
Objective: To assessed in vitro the effect of nanohydroxyapatite (n‐HA) to improve the aesthetic appearance and microhardness of white spot lesions (WSL) when associated with a low‐concentration bleaching agent (carbamide peroxide—CP10%). Material and methods: Enamel/dentin specimens (n = 60) of 5 × 5 × 2.2 mm were prepared, of these, 48 were submitted to pH‐cycling to create artificial WSL. Subsequently, these were allocated into five groups (n = 12): n‐HA; n‐HA + CP10%; CP10%; WSL control (WSLC); sound control (Sound). The color was assessed at baseline, pre‐treatment, and post‐treatment using a spectrophotometer, and the color (ΔE/ΔE00) and whiteness index (ΔWID) alterations were determined. The enamel cross‐sectional microhardness (CSMH) was evaluated (post‐treatment) with a Knoop indenter, 25gf/5 s, 20–200 μm. The data was analyzed through generalized linear models (α = 5%). Results: ΔE and ΔE00 were significantly higher for the bleached groups (n‐HA + CP10% and CP10%), and the n‐HA was higher than the WSLC group (p < 0.05). ΔWID was significantly higher for the bleached groups (p < 0.05). The CSMH values were significantly higher in the sound group than in the n‐HA, CP10%, and WSLC groups (p < 0.05). The WSLC had lower microhardness than the n‐HA + CP10% and sound groups (p < 0.05). Conclusion: n‐HA is suitable to remineralize and recover the color of the WSL. However, its association with CP10% maintains the esthetical outcome while increasing its in‐depth remineralizing effect. Clinical significance: Considering the aesthetic and functional repercussions of the WSL persistence, treatments that tend to improve its physical appearance and reinforce its weakened substructure in a non‐invasive way are ideal. For this associating low‐concentration, bleaching agents to the remineralizing treatments is promising to treat this type of lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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107. Effect of Different Bleaching Gels Thickeners on Cytotoxicity to Human Gingival Fibroblasts and Enamel Physical Properties: an in Situ Study.
- Author
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Guerra Silva, Bruna, Pereira, Renata, Burga Sánchez, Jonny, GuanipaOrtiz, Mariangela Ivette, Baggio Aguiar, Flávio Henrique, and Nunes Leite Lima, Débora Alves
- Subjects
BLEACHING (Chemistry) ,THICKENING agents ,DENTAL enamel ,FIBROBLASTS ,CARBAMIDE peroxide ,TOOTH whitening - Abstract
Copyright of Acta Stomatologica Croatica is the property of Acta Stomatologica Croatica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
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108. Digital evaluation of dental bleaching using a new methodology: an in vivo study.
- Author
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Salehi, Ali, He, Matthieu, Hampe-Kautz, Vincent, and Etienne, Olivier
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TOOTH whitening ,DENTAL photography ,CARBAMIDE peroxide ,IN vivo studies ,DENTAL care - Abstract
Objective: The objective of the present study was to assess the progress and efficiency of at-home bleaching protocols with 10% carbamide peroxide using a new methodology based on dental photography. Materials and methods: A 4-week overnight at-home bleaching protocol using whitening trays and 10% carbamide peroxide was performed on 52 patients. The tooth color was analyzed using standardized photographs taken every week for 4 weeks and at 4 months posttreatment. The values of the color evolution (AE00), L*, a*, and b* were also measured and used to assess the evolution of the chroma, luminosity, and hue using the CIEDE2000 formula. The statistical analyses were conducted at a significance level of P < 0.05 by means of a repeated measures analysis of variance (ANOVA). Results: The tooth color changed the most, and thus the highest AE00 was observed, after the first week of treatment. The color continued to change but to a lesser degree during the following weeks. After 4 weeks, the treatment proved to be very effective. Four months after the end of treatment, a color relapse was observed, though it was hardly perceptible to the human eye. The luminosity (L') changed significantly between the beginning and the end of treatment, affecting the maxilla to a greater extent. The chroma evolution showed a high variance and a low; elapse for both jaws. The hue was not affected significantly during the treatment and the stabilization. Conclusions: Within the limitations of the present study, the authors were able to assess the progress and efficiency of at-home bleaching with 10% carbamide peroxide in terms of chroma, luminosity, and hue using a new methodology based on dental photography. Clinical significance: This new method is effective and enables a reliable analysis of the evolution of a dental bleaching treatment, turning dental photography into an even more powerful tool for analysis and communication. It can also be used as a proof-of-concept, paving the way for further research on objective monitoring and evaluation of dental treatments using dental photography. (Int J Esthet Dent 2022;17:2-20) [ABSTRACT FROM AUTHOR]
- Published
- 2022
109. Effects of repeated home bleaching on the surface roughness of CAD-CAM restoration materials.
- Author
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Çölgeçen, Özlem and Köse, Mehmet
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SURFACE roughness ,HYBRID materials ,CARBAMIDE peroxide ,POLYMER networks ,ROUGH surfaces - Abstract
Aim: This study aimed to investigate the effects of the repeated usage of a home-bleaching agent (16% carbamide peroxide) on the surface roughness of commonly used computer-aided design-computer-aided manufacture (CAD-CAM) restoration materials. Methodology: Five different CAD-CAM restoration materials were used in this study: feldspathic ceramic (Vita Mark II-Group VM II), leucite-reinforced glass ceramic (IPS Empress CAD-Group EMP), lithium disilicate-reinforced glass ceramic (IPS e.max CAD-Group EMAX), polymer infiltrated network hybrid ceramic (Vita Enamic-Group VE), and resin nanoceramic (Lava Ultimate-Group LU). A home-bleaching agent containing 16% carbamide peroxide was applied in three repeated periods (10 days, 20 days, and 30 days of exposure). A surface profilometer was used to determine the roughness average (Ra) values of the specimens. The data obtained were statistically analyzed using repeated measures of the analysis of variance (ANOVA) and Bonferroni post-hoc test at a 5% level of significance. Results: All materials exhibited a rougher surface after the first treatment period (10 days of exposure). The roughness of Group VM II continued to increase for up to 20 days. With the exception of Group LU, all groups exhibited a significantly rougher surface after 30 days of exposure compared to the baseline values (p < 0.05). The greatest variation in surface roughness was observed for the ceramic-based groups (VM II, EMP, and EMAX) rather than the hybrid groups (LU and VE). Conclusion: Patients with ceramic-based CAD-CAM restorations should be careful during home-bleaching treatment, especially when repeated applications are involved. Hybrid materials, particularly Lava Ultimate, seem more resistant to the effects of repeated bleaching cycles than ceramic-based materials. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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110. Comparative Analysis Between Strip and Gels Indicated for at Home Bleaching: Analysis of Color Alteration, Roughness and Microhardness of Dental Enamel.
- Author
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Aidar KMS, Cintra LTA, Ferreira MCB, Fagundes TC, Esteves LMB, Goto J, Catelan A, and Briso ALF
- Abstract
Purpose: To compare the color alteration, surface roughness and microhardness and cross-sectional microhardness of bovine enamel treated with at-home whitening strips and gels., Materials and Methods: Sixty-six pigmented specimens (n = 11) were allocated to six groups: C-cotton wool moistened with distilled water for 1 h; SDS-sodium dithionite strip, for 1 h; HPS-6.5% hydrogen peroxide strip, for 1 h; CPS-20% carbamide peroxide strip, for 1 h; HPG-7.5% hydrogen peroxide gel, for 1 h; CPG-10% carbamide peroxide gel, for 4 h. The treatments lasted 10 days, calculating the ∆E, ∆E
00 , and ∆WID at baseline, 5 and 10 days, and 14 days after completion. Additional 66 polished discs (n = 11) were used to analyze the surface roughness and microhardness of enamel before and after bleaching, cross-sectional microhardness and integrated mineral loss (ΔZ; %Vol × μm). Data were subjected to statistical analysis by two-way Anova RM and Tukey post-test (α = 0.05)., Results: In ∆E and ∆WID analysis, greater values were obtained in CPG (p < 0.001), followed by HPG and HPS (p = 0.271). SDS and CPS (p < 0.001) exceeded only C (p < 0.001). In ∆E00 , at completion of treatments, the results were similar; however, HPG = HPS = CPS (p = 0.237). There was an increase in roughness and decrease in surface microhardness in all bleaching groups (p < 0.005). Concerning the cross-sectional microhardness, the treatments were equal to C at 150 μm, the last depth analyzed. For ΔZ, the values of SDS, CPS, HPG, and CPG groups showed similar mineral loss (p > 0.001), and the lowest value was exhibited in the Control group, followed by HPS group (p < 0.001)., Conclusion: Although the strips were aesthetically effective, the CPG and HPG groups presented highest values in the ∆E00 and ∆WID analysis. However, all treatments influenced the enamel surface, increasing roughness and decreasing surface and transverse microhardness., Clinical Relevance: The whitening gels promoted greater chromatic changes, but all treatments affected the enamel surface, increasing roughness and decreasing surface and transverse microhardness., (© 2025 Wiley Periodicals LLC.)- Published
- 2025
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111. Effects of home bleaching agents on hybrid ceramics: mechanical properties and color change.
- Author
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Hafny WM, Ibrahim IM, El-Demellawy M, and Abdel Sadek HM
- Subjects
- Peroxides, Tooth Bleaching methods, Flexural Strength, Urea analogs & derivatives, Urea chemistry, Urea pharmacology, Humans, Dental Porcelain chemistry, Surface Properties, Color, Carbamide Peroxide, Tooth Bleaching Agents chemistry, Ceramics chemistry, Materials Testing
- Abstract
Background: Home bleaching is a promising option for addressing discolored teeth conservatively. However, its impact on the physical and mechanical properties of indirect restorations remains unknown. This study provides comparative insights into the material responses to aesthetic treatments by assessing the effects of home bleaching agents on two hybrid ceramics: VITA ENAMIC
® and Grandio Blocs. The focus is on evaluating color stability and biaxial flexural strength., Methods: 60 discs (12 × 1 mm) were prepared from hybrid ceramics. Specimens were divided into two groups according to type of hybrid ceramic (30 specimens in each group); group A: VITA ENAMIC® , group B: Grandio Blocs. Each group was further subdivided into 3 subgroups according to the concentration of home bleaching agents used (10 specimens in each subgroup); subgroup C: unbleached control group, subgroup C10%: carbamide peroxide 10% bleaching agent, and subgroup C35%: carbamide peroxide 35% bleaching agent. Samples of subgroup C10% were bleached with Home Bleaching Opalescence PF (10%) for 8 h per day for 14 days, as directed by the manufacturer. Samples of subgroup C35% were bleached using WHITEsmile Carbamide Peroxide (35%), following the manufacturer's directions for 30 min every day for 14 days. Color change (ΔE) was assessed using of the CIE L*a*b* system. Then, the biaxial flexural strength test was done. The data were analyzed using two-way ANOVA tests and Weibull analysis., Results: VITA ENAMIC samples exhibited significantly higher color change than Grandio Blocs (p < 0.001), while Grandio Blocs showed significantly higher biaxial flexural strength (p < 0.001). The concentration of the bleaching agent had no significant effect on color change (p = 0.086). However, regardless of its concentration, bleaching significantly reduced biaxial flexural strength in both materials (p < 0.001). Weibull analysis showed that Grandio Blocs had higher characteristic strength, while VITA ENAMIC demonstrated more reliable failure behavior., Conclusions: Compared to Grandio Blocs, VITA ENAMIC® exhibited a greater color change with both 10% and 35% carbamide peroxide home bleaching agents. Additionally, both concentrations of carbamide peroxide reduced the biaxial flexural strength of hybrid ceramics. These findings can guide clinicians in selecting hybrid ceramics based on clinical demands for aesthetics and durability. VITA ENAMIC® offers greater structural reliability and predictability for aesthetic restorations, while Grandio Blocs provide superior durability and stress resistance for high-stress clinical applications., Competing Interests: Declarations. Ethics approval and consent to participate: Ethics committee approval: FDAsu-RecEMo22311 (Research ethics committee of Faculty of Dentistry Ain Shams University) was obtained. Consent of publication: Not applicable. Competing interests: The authors declare no competing interests., (© 2024. The Author(s).)- Published
- 2025
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112. Comparative evaluation of different access cavity designs on intracoronal bleaching of endodontically treated teeth using two different agents – An in vitro study
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Sonali Talwar, Pardeep Mahajan, Nitika Bajaj, Prashant Monga, Pratibha Marya, and Piyush Gandhi
- Subjects
access cavity designs ,carbamide peroxide ,hydrogen peroxide ,intracoronal tooth bleaching ,nonvital ,Dentistry ,RK1-715 - Abstract
Aim: The present in vitro study was designed to determine the effect of different access cavity designs on intracoronal bleaching of endodontically treated teeth with two different agents. Materials and Methods: Fifty selected permanent maxillary central incisors were stained. Traditional and contracted access cavity designs and two types of bleaching agents, i.e., 35% carbamide peroxide and 35 percent hydrogen peroxide were used for the study. Color measurements were performed with a spectrophotometer: before staining (T1), after staining (T2), at 7 and 14 days (T3 and T4) post bleaching. The values were calculated and subjected to the statistical analysis. Results: The results of our study showed that teeth in which traditional access cavity (TAC) was prepared had statistically significant better bleaching results with both 35% carbamide peroxide and 35% hydrogen peroxide than contracted access cavity design. Carbamide peroxide showed better results than hydrogen peroxide irrespective of the access cavity design, but difference was statistically nonsignificant. Conclusion: The present study concluded that TAC design showed better results than contracted access with both carbamide peroxide and hydrogen peroxide. Whereas, when bleaching agents were compared 35% carbamide peroxide is better than 35% hydrogen peroxide irrespective of access cavity design used.
- Published
- 2022
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113. Patent Application Titled 'Hypertonic Antimicrobial Therapeutic Compositions' Published Online (USPTO 20240350635)
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Intellectual property ,Carbamide Peroxide - Abstract
2024 NOV 15 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Patent Business Week -- According to news reporting originating from Washington, D.C., by NewsRx journalists, a patent [...]
- Published
- 2024
114. 'Hypertonic Antimicrobial Therapeutic Compositions' in Patent Application Approval Process (USPTO 20240350636)
- Subjects
Intellectual property ,Carbamide Peroxide - Abstract
2024 NOV 15 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Patent Business Week -- A patent application by the inventor ABRAHMSOHN, Glenn (Key Biscayne, FL, US), filed [...]
- Published
- 2024
115. Patent Application Titled 'Portable Teeth Whitening Apparatus' Published Online (USPTO 20240269477)
- Subjects
Intellectual property ,Carbamide Peroxide - Abstract
2024 SEP 6 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- According to news reporting originating from Washington, D.C., by NewsRx journalists, a patent [...]
- Published
- 2024
116. Patent Issued for Hypertonic antimicrobial therapeutic compositions (USPTO 12059466)
- Subjects
Intellectual property ,Microbial drug resistance ,Carbamide Peroxide ,Drug resistance in microorganisms - Abstract
2024 SEP 6 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Patent Business Week -- A patent by the inventors Abrahmsohn, Glenn (Key Biscayne, FL, US), filed on [...]
- Published
- 2024
117. Excessive Dental Bleaching with 22% Carbamide Peroxide Combined with Erosive and Abrasive Challenges: New Insights into the Morphology and Surface Properties of Enamel.
- Author
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Barros Júnior, Edson de Sousa, Ribeiro, Mara Eliane Soares, Lima, Rafael Rodrigues, Souza Júnior, Mário Honorato da Silva e, and Loretto, Sandro Cordeiro
- Subjects
- *
TOOTH whitening , *CARBAMIDE peroxide , *AMELOBLASTS , *SURFACE properties , *DENTAL enamel , *SURFACE morphology , *PEROXIDES , *DENTAL glass ionomer cements - Abstract
This study aimed to evaluate the effects of 22% carbamide peroxide combined with an erosive challenge and simulated brushing on enamel. Bovine incisor teeth were divided into G1, tooth bleaching; G2, tooth bleaching + erosive challenge; and G3, tooth bleaching + erosive challenge + simulated brushing, and evaluated at T0, before any intervention; T1, 14 days after the proposed treatments; and T2, 28 days after the proposed treatments. Tooth bleaching was performed daily for 1 h for 28 days. The microhardness, surface roughness, mass variation, and ultrastructure were analyzed at T0, T1, and T2. Two-way analysis of variance for repeated measures was performed and Tukey's post hoc test (α = 5%) was used. The surface roughness increased in groups G2 and G3 as a function of time, whereas microhardness and mass measurements demonstrated a significant reduction for groups associated with challenges. Ultrastructural evaluation indicated a loss of the aprismatic layer and exposure of the enamel prisms in all groups after 14 days of bleaching, with more pronounced results in G2 and G3 after 28 days. In conclusion, abrasive and erosive challenges potentiated the deleterious effects of tooth whitening on microhardness, ultramorphology, and mass, without affecting the roughness of dental enamel. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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118. The Effectiveness of Dental Bleaching during Orthodontic Treatment with Clear Aligners: A Systematic Review.
- Author
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Khashashneh, Majd, Ratnayake, Jithendra, Choi, Joanne Jung Eun, Mei, Li, Lyons, Karl, and Brunton, Paul A.
- Subjects
TOOTH whitening ,ORTHODONTIC appliances ,CORRECTIVE orthodontics ,TEETH ,ELECTRONIC information resource searching - Abstract
The objective of this article was to systematically review the literature to determine how effective tooth whitening procedures are when carried out in tandem with orthodontic clear aligners. This systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Online searches of PubMed, Medline via Ovid, Science Direct, the Cochrane database of systematic reviews via Ovid, Scopus, and Google Scholar as well as manual searches of the references of the selected articles were conducted. Clinical studies which assessed the efficacy of dental bleaching using orthodontic clear aligners were included in the present study. Data from the included studies were extracted and assessed for risk of bias using the Cochrane risk of bias tool. Three studies met the inclusion and exclusion criteria and were included in this study. One study compared the efficiency of tooth bleaching between clear aligners and conventional bleaching trays. One study evaluated the effectiveness of dental bleaching using clear aligners by comparing the tooth shade of those patients to a control group of patients who did not receive dental bleaching during orthodontic clear aligner treatment. One study evaluated the effectiveness of different concentrations of different bleaching agents using clear aligners. All the included studies showed an improved tooth shade when using clear aligners as bleaching trays. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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119. A highly effective therapeutic ointment for treating corals with black band disease.
- Author
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Eaton, Katherine R., Clark, Abigail S., Curtis, Katie, Favero, Mike, Hanna Holloway, Nathaniel, Ewen, Kristen, and Muller, Erinn M.
- Subjects
- *
CORAL diseases , *CORALS , *OINTMENTS , *CORAL declines , *CARBAMIDE peroxide , *NATIONAL monuments - Abstract
Infectious disease outbreaks are a primary contributor to coral reef decline worldwide. A particularly lethal disease, black band disease (BBD), was one of the first coral diseases reported and has since been documented on reefs worldwide. BBD is described as a microbial consortium of photosynthetic cyanobacteria, sulfate-reducing and sulfide-oxidizing bacteria, and heterotrophic bacteria and archaea. The disease is visually identified by a characteristic dark band that moves across apparently healthy coral tissue leaving behind bare skeleton. Despite its virulence, attempts to effectively treat corals with BBD in the field have been limited. Here, we developed and tested several different therapeutic agents on Pseudodiploria spp. corals with signs of active BBD at Buck Island Reef National Monument in St. Croix, USVI. A variety of therapies were tested, including hydrogen peroxide-based treatments, ointment containing antibiotics, and antiviral/antimicrobial-based ointments (referred to as CoralCure). The CoralCure ointments, created by Ocean Alchemists LLC, focused on the dosing regimen and delivery mechanisms of the different active ingredients. Active ingredients included carbamide peroxide, Lugol's iodine solution, along with several proprietary essential oil and natural product blends. Additionally, the active ingredients had different release times based on treatment: CoralCure A-C had a release time of 24 hours, CoralCure D-F had a release time of 72 hours. The ointments were applied directly to the BBD lesion. Also, jute rope was saturated with a subset of these CoralCure ointment formulations to assist with adhesion. These ropes were then applied to the leading edge of the BBD lesion for one week to ensure sufficient exposure. Corals were revisited approximately three to five months after treatment application to assess disease progression rates and the presence/absence of lesions—the metrics used to quantify the efficacy of each treatment. Although most of the treatments were unsuccessful, two CoralCure rope formulations—CoralCure D rope and CoralCure E rope, eliminated the appearance of BBD in 100% of the corals treated. As such, these treatments significantly reduced the likelihood of BBD occurrence compared to the untreated controls. Additionally, lesions treated with these formulations lost significantly less tissue compared with controls. These results provide the mechanisms for an easily employable method to effectively treat a worldwide coral disease. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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120. Effect of bioactive glass paste on efficacy and post-operative sensitivity associated with at-home bleaching using 20% carbamide peroxide: a randomized controlled clinical trial.
- Author
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Bizreh, Yazan and Milly, Hussam
- Subjects
BLEACHING (Chemistry) ,CARBAMIDE peroxide ,BIOACTIVE glasses ,CLINICAL trials ,RANDOMIZED controlled trials ,TOOTH sensitivity - Abstract
Background: The aim of this study was to evaluate the effect of bioactive glass (BAG) 45S5 paste on colour change and tooth sensitivity (TS) when used in combination with 20% carbamide peroxide (CP) during at-home vital tooth bleaching. Methods: Twenty-four patients were selected and assigned into two experimental groups (n = 12) in a double-blind study design. Each patient received 20% CP followed by the application of either BAG paste or non-active placebo paste. The shade evaluation was performed using a digital spectrophotometer based on the CIE L*a*b* colour space system at different time points and the overall colour changes ΔE were calculated. TS was evaluated using visual analogue scale (VAS). The values of ΔE and TS were statistically analysed using paired t-test. The level of statistical significance was established at p = 0.05. Results: The overall colour changes (ΔE) between baseline and each time point showed no significant differences between BAG and placebo groups (p > 0.05). The use of BAG paste significantly decreased TS reported by the participants. Conclusions: The association of BAG paste with at-home bleaching treatment presents a promising method as it decreased TS and did not deteriorate bleaching efficacy. Trial registration This study was approved and registered in the Australian New Zealand Clinical Trials Registry (ANZCTR) under Registration number: ACTRN12621001334897. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
121. Present status and future directions – Managing discoloured teeth.
- Subjects
- *
DENTAL discoloration , *CARBAMIDE peroxide , *ROOT resorption (Teeth) , *SODIUM perborate , *TOOTH whitening - Abstract
Managing tooth discolouration involves a range of different protocols for clinicians and patients in order to achieve an aesthetic result. There is an increasing public awareness in the appearance of their teeth and management of tooth discolouration may be inter‐disciplinary and involve both vital and nonvital teeth. Vital teeth can be easily treated with low concentration hydrogen peroxide products safely and effectively using an external approach and trays. For endodontically treated teeth, the walking bleach technique with hydrogen releasing peroxide products is popular. However, there is an association with external cervical root resorption with higher concentrations of hydrogen peroxide of 30%–35%. There are also regulatory considerations for the use of hydrogen peroxide in certain jurisdictions internationally. Prosthodontic treatments are more invasive and involve loss of tooth structure as well as a life cycle of further treatment in the future. This narrative review is based on searches on PubMed and the Cochrane library. Bleaching endodontically treated teeth can be considered a safe and effective protocol in the management of discoloured teeth. However, the association between bleaching and resorption remains unclear although there is likely to be a relation to prior trauma. It is prudent to avoid thermocatalytic approaches and to use a base/sealer to cover the root filling. An awareness expectations of patients and multidisciplinary treatment considerations is important in achieving the aesthetic result for the patient. It is likely that there will be an increasing demand for aesthetic whitening treatments. Bleaching of teeth has also become increasingly regulated although there are international differences in the use and concentration of bleaching agents. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
122. Effectiveness and safety of bleaching agents on lithium disilicate glass ceramics.
- Author
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Ozdogan, Alper and Kaya, Nihan
- Subjects
LITHIUM ,THERAPEUTIC use of lithium ,BLEACHING (Chemistry) ,CARBAMIDE peroxide ,CERAMICS ,DENTAL materials ,COSMETIC dentistry - Abstract
Background.: Aesthetic expectations have increased the use of aesthetic materials in dentistry. Lithium disilicates are frequently used materials for these expectations. Bleaching is another method used to provide aesthetics. Bleaching processes on restorative materials are not fully known. This study investigated the effect of at-home and in-office bleaching methods on the color change, surface roughness, and topography of lithium disilicate glass-ceramic materials produced with two different techniques and subjected to different polishing procedures. Methods.: A total of 144 disc-shaped pressed and computer-aided design (CAD) lithium disilicate glass-ceramic specimens were randomly divided into four groups. Glazing and three different chair-side polishing procedures were performed. The specimens in each group were randomly divided into two groups and subjected to at-home and in-office bleaching processes (n=9). The home bleaching process was repeated with 16% carbamide peroxide agent for six hours for seven days, while the in-office bleaching process was applied with 40% hydrogen peroxide agent for two sessions of 20 minutes. After the bleaching processes, the final color and surface roughness experiments of the specimens were carried out, and the results were recorded. ANOVA and Tukey multiple comparison tests were used FOR the statistical analysis of the data (α=0.05). Results.: The material*polish*bleaching, polish*bleaching, material*bleaching, and material*polishing interactions were not statistically significant regarding color and roughness changes of both specimens (P >0.05). Conclusion.: Both bleaching processes can be safely applied to lithium disilicate glass-ceramic materials. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
123. The effect of immersion in beverages and dental bleaching agents on the surface roughness of resin composites.
- Author
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Korać, Samra, Tahmiščija, Irmina, Hasić-Branković, Lajla, Bajrić, Elmedin, Džanković, Aida, Konjhodžić, Alma, and Softić, Almira
- Subjects
- *
SURFACE roughness , *TOOTH whitening , *CARBAMIDE peroxide , *INSTANT coffee , *GREEN tea - Abstract
Introduction: Composite materials may be exposed to chemicals in food and beverages in the oral cavity, which can lead to changes in surface roughness. The aim of this in vitro study was to evaluate the surface roughness of two restorative materials after exposure to coffee and green tea followed by a dental bleaching procedure. Methods: For nanofilled composite and microhybrid composite, 15 samples each were fabricated. Five specimens from each composite were stored in instant coffee and green tea for 4 h a day. After 30 days of immersion, specimens received dental at-home bleaching, using 16% carbamide peroxide (CP), for 7 h a day. The control group was stored in deionized water for 30 days. Surface roughness was determined by profilometry 24 h after polymerization, after 30 days of immersion, and after bleaching. The data were analyzed using a t-test for paired samples and mixed analysis of variance, at a 0.05 significance level. Results: Neither beverages nor CP treatment significantly altered the surface roughness of the composites. There was no difference between the tested composite materials regarding roughness. Conclusion: Surface roughness of the microhybrid and nanohybrid composites was not modified by coffee, green tea, and subsequent whitening treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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124. The Effect of Home and In-Office Bleaching on Microhardness and Color of Different CAD/CAM Ceramic Materials.
- Author
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Alshali, Ruwaida Z. and Alqahtani, Mohammed A.
- Subjects
- *
LITHIUM silicates , *MICROHARDNESS , *CARBAMIDE peroxide , *COLORIMETRY , *HYDROGEN peroxide , *COLOR , *CERAMICS , *CERAMIC materials - Abstract
The aim of this study is to assess the effect of different bleaching agents on microhardness and color of CAD/CAM ceramics including IPS e.max CAD (lithium disilicate), VITA ENAMIC (polymer-infiltrated ceramic), and Celtra Duo CAD (zirconia-reinforced lithium silicate). Materials' samples were divided into three groups (n = 10) and each received a different bleaching treatment; 20% carbamide peroxide, 35% carbamide peroxide, and 40% hydrogen peroxide. A fourth group was stored in water acting as a control. Vickers microhardness and spectrophotometric color measurements were taken at baseline and after bleaching. IPS e.max CAD showed a significant reduction (about 14%), while VITA ENAMIC showed a significant increase (about 78%) in microhardness after bleaching (p ˂ 0.001). Celtra Duo CAD did not demonstrate a significant change in microhardness (p ≥ 0.609). The color difference (ΔEab) after bleaching was 0.29 (±0.08), 2.84 (±0.64), and 1.99 (±0.37) for IPS e.max CAD, VITA ENAMIC, and Celtra Duo CAD, respectively. It could be concluded that the effect of bleaching on color and microhardness was mainly material-dependent. Bleaching significantly affected the microhardness of IPS e.max CAD and VITA ENAMIC. The color difference was within the clinically imperceptible range for IPS e.max CAD, while VITA ENAMIC and Celtra Duo CAD demonstrated perceptible color change. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
125. Influence of a bleaching agent on surface and mechanical properties of orthodontic thermoplastic retainer materials: An in vitro study.
- Author
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Babanouri, Neda, Ahmadi, Nazanin, Pakshir, Hamid Reza, Ajami, Shabnam, and Habibagahi, Raha
- Subjects
ORTHODONTIC retainers ,SURFACE properties ,CARBAMIDE peroxide ,TOOTH whitening ,POLYETHYLENE terephthalate - Abstract
Copyright of Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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126. Researchers from Sao Paulo State University (UNESP) Detail New Studies and Findings in the Area of Obesity, Fitness and Wellness (Comparative Analysis Between Strip and Gels Indicated for At Home Bleaching: Analysis of Color Alteration,...).
- Abstract
A recent study conducted by researchers from Sao Paulo State University (UNESP) compared the effects of at-home whitening strips and gels on bovine enamel. The study found that whitening gels led to greater chromatic changes, while both strips and gels increased roughness and decreased surface and transverse microhardness of the enamel. The research was supported by Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) and has been peer-reviewed. For more details, the study can be found in the Journal of Esthetic and Restorative Dentistry. [Extracted from the article]
- Published
- 2025
127. Patent Application Titled "Salts Of A Pim Kinase Inhibitor" Published Online (USPTO 20250019366).
- Subjects
CARBAMIDE peroxide ,MANTLE cell lymphoma ,PATENT applications ,HEAD & neck cancer ,ADIPIC acid - Abstract
A patent application titled "Salts Of A Pim Kinase Inhibitor" was published online on January 16, 2025, by inventors from various locations in the United States. The application focuses on the development of new forms of Pim-inhibiting molecules to aid in the treatment of cancer. The invention includes various salts and crystalline forms of the inhibitor, along with pharmaceutical compositions and therapeutic methods for their use. [Extracted from the article]
- Published
- 2025
128. Studies in the Area of Obesity, Fitness and Wellness Reported from Sao Paulo State University (UNESP) (Color Change and Cytotoxic Effects of a Bleaching Gel With 22% Carbamide Peroxide Catalyzed By Manganese Oxide).
- Abstract
Researchers from Sao Paulo State University conducted a study to evaluate the color change and cytotoxic effects of a bleaching gel with 22% carbamide peroxide catalyzed by manganese oxide. The study found that adding 10 mg/mL of MnO2 to the bleaching gel increased efficacy and reduced cytotoxicity, making it a promising strategy for at-home bleaching therapy. The research was supported by Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ). [Extracted from the article]
- Published
- 2025
129. Ain Shams University Researchers Publish New Data on Oral Health (Effects of home bleaching agents on hybrid ceramics: mechanical properties and color change).
- Abstract
A recent study conducted by researchers at Ain Shams University focused on the effects of home bleaching agents on hybrid ceramics used in dental restorations. The study compared the impact of bleaching agents on two types of hybrid ceramics, VITA ENAMIC(R) and Grandio Blocs, in terms of color stability and biaxial flexural strength. Results showed that VITA ENAMIC exhibited greater color change with both 10% and 35% carbamide peroxide bleaching agents, while Grandio Blocs demonstrated higher biaxial flexural strength. The findings suggest that clinicians can choose hybrid ceramics based on specific clinical requirements for aesthetics and durability. [Extracted from the article]
- Published
- 2025
130. Section of Dentistry Researcher Reports on Findings in Bioengineering (Evaluation of the Effectiveness of Different Types of Professional Tooth Whitening: A Systematic Review).
- Abstract
A recent study conducted in Pavia, Italy, evaluated the effectiveness of different types of professional tooth whitening treatments using hydrogen or carbamide peroxide. The research, which included 30 articles, found that all types of bleaching were effective in changing tooth color, with at-home trays using carbamide peroxide gel showing lower recurrence rates compared to in-office treatments. However, there were mixed findings on tooth sensitivity, which appeared to be higher in professional in-office and combined dental bleaching. The study concluded that bleaching is an effective treatment for changing tooth color, but may carry a risk of tooth sensitivity post-treatment. [Extracted from the article]
- Published
- 2024
131. NEWS BRIEFS
- Subjects
Scholarships (Financial aid) ,Carbamide Peroxide ,Scholarships - Abstract
November 1 Deadline for ADAA/DANB Scholarship ADAA and the Dental Assisting National Board, Inc. (DANB) are accepting applications for the 2021 ADAA/DANB Scholarship. Since 2013, this scholarship has provided dental [...]
- Published
- 2021
132. VITAL AND NON-VITAL TOOTH BLEACHING PROCEDURES: A SURVEY AMONG DENTISTS FROM ROMANIA
- Author
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Alexandru Dan Popescu, Marina Valentina Purcarea, Ruxandra Voinea Georgescu, Ionela Teodora Dascălu, Adina Turcu, Andreea Gabriela Nicola, Luminița Dăguci, Tiberiu Tircă, Mihaela Jana Tuculina, and Adrian Camen
- Subjects
hydrogen peroxide ,carbamide peroxide ,questionnaire ,home bleaching ,walking bleach ,Dentistry ,RK1-715 - Abstract
Changes in tooth form, texture and shade inevitably accompany the aging of the people. The desire of improving smile appearance leads to an increase in the request of esthetic dental procedures. Bleaching is now the most common and non-invasive esthetic dental treatment. Even if it is considered a cosmetic dental treatment, the dentist always should establish a diagnosis and treatment plan before initiate the procedure. This study aims to evaluate the Romanian dentists approach to vital and non-vital bleaching procedures and to assess if there are correlations between their options and the time of clinical practice or the postgraduate training. The cross-sectional study was undertaken using a closed questionnaire addressed to dentists by online method. The twenty questions focused on the following topics: time of clinical practice, self-perception on safety of the treatment, self-confidence in providing bleaching, postgraduate training, the main technique for vital and non-vital tooth bleaching therapies, first choice material, the use of light activation, the need for desensitizing agents and the attitude towards restorations.
- Published
- 2021
133. Researchers Submit Patent Application, 'Peroxide Gel Compositions', for Approval (USPTO 20230346655)
- Subjects
Intellectual property ,Hydrogen peroxide -- Intellectual property ,Physical fitness ,Otic preparations -- Intellectual property ,Urea ,Carbamide Peroxide - Abstract
2023 NOV 25 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- From Washington, D.C., NewsRx journalists report that a patent application by the [...]
- Published
- 2023
134. Researchers Submit Patent Application, 'Dental Whitening Composition', for Approval (USPTO 20230330445)
- Subjects
Intellectual property ,Physical fitness ,Otic preparations -- Intellectual property ,Carbamide Peroxide - Abstract
2023 NOV 11 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- From Washington, D.C., NewsRx journalists report that a patent application by the [...]
- Published
- 2023
135. INSPIRED BY SKIN CARE, ORAL CARE MOVES BEYOND HYGIENE: Thanks to skin care inspiration and holistic well-being philosophies, oral care has a bigger role to play in wellness.
- Subjects
SKIN care ,WELL-being ,ORAL hygiene products ,CARBAMIDE peroxide ,INSPIRATION - Abstract
Oral care is expanding beyond hygiene and taking inspiration from skin care trends and holistic well-being philosophies. The global oral care market is projected to reach $36.4 billion by 2034, with North America and China being key growth centers. Consumers are increasingly seeking clinically tested and proven formulations, and dentists are becoming influential in guiding oral care choices. Peptides, hydroxyapatite, and probiotics are emerging ingredients in oral care products, reflecting the influence of skin care and addressing various oral health needs. This article highlights the evolving landscape of oral care and its connection to overall health and well-being. [Extracted from the article]
- Published
- 2024
136. Evaluation of Bleaching with Carbamide Peroxide on Microhardness, Mineral Content, and Color Change of White Spot Lesions
- Author
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abdolrahim davari, Alireza Daneshkazemi, Farnaz Farahat, Elham motallebi, and sepideh abbasi
- Subjects
tooth bleaching ,carbamide peroxide ,hardness tests ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background and Objective: Tooth bleaching changes the microhardness and mineral content and color of the tooth. The present study aimed to evaluate the effect of carbamide peroxide on microhardness, mineral content and color change in white spot lesions. Material and Methods: Thirty-two samples were selected without caries, cracks and stains, and immersed in 0.5% chloramine-T for one week. Then the tooth crowns were separated. The teeth were artificially decayed by pH cycling. For bleaching on the enamel, a coating of 10% carbamide peroxide gel with a thickness of 1 mm was used for 8 hours. Samples were stored in artificial saliva for 16 hours. Bleaching process lasted for 14 days. Microhardness, color changes, calcium and phosphorus levels were measured before and after bleaching. Paired t-test and one-sample test were used to analyze the data. Results: The microhardness test results were 338.02± 90.15 and 320.94±87.41 before and after bleaching, respectively. microhardness of the samples significantly decreased after bleaching compared to before bleaching (P0.05). The mean color change coefficient (∆E) after bleaching was 6.82±3.96. ∆E in the studied samples was significantly higher than the standard (∆E =3.3). Conclusion: Bleaching with 10% carbamide peroxide significantly reduced microhardness. There was no change in the mineral content of the enamel and color change was proper. It can be concluded from this study that bleaching with carbamide peroxide can be successful.
- Published
- 2021
137. Pazufloxacin Mesilate Ear Drops in Patients With Chronic Suppurative Otitis Media
- Published
- 2018
138. Efficacy of Carbamide and Hydrogen Peroxide Tooth Bleaching Techniques in Orthodontic and Restorative Dentistry Patients: A Scoping Review
- Author
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Giuseppina Malcangi, Assunta Patano, Alessio Danilo Inchingolo, Anna Maria Ciocia, Fabio Piras, Giulia Latini, Chiara Di Pede, Giulia Palmieri, Claudia Laudadio, Vito Settanni, Grazia Garofoli, Elisabetta de Ruvo, Silvio Buongiorno, Ioana Roxana Bordea, Edit Xhajanka, Daniela Di Venere, Francesco Inchingolo, Gianna Dipalma, and Angelo Michele Inchingolo
- Subjects
carbamide peroxide ,composites ,dental bleaching ,hydrogen peroxide ,orthodontics ,tooth bleaching ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Background: Dental aesthetic procedures aim to rectify flaws in dental elements’ shape, alignment, or overly dark color. One of the most common dental aesthetic procedures is tooth whitening. This study attempts to introduce key aspects of bleaching and describe the different techniques and the mechanism of action of bleaching agents, focusing on the clinical implications in orthodontic and on composite restorations. Methods: The research was performed on PubMed, Web of Science, and Science Direct databases for articles on our topic published between 2017 and 2023, and we found a total of 1512 studies. In total, 57 papers were considered for the qualitative analysis in the review. Results: This study found that both carbamide peroxide and hydrogen peroxide were clinically effective, although patients’ level of tooth sensitivity seemed to be lessened by the latter. However, the latter appears to be more effective at reducing patient-experienced tooth sensitivity. Conclusion: Carbamide and hydrogen peroxide based whitening techniques were shown to be equally successful at treating tooth discoloration after bracket composite removal, with no discernible differences between them. To increase the effectiveness of whitening on composites, more research is needed. To achieve the desired results and avoid the negative effects of whitening gels on teeth and soft tissue, a patient-specific approach is advised.
- Published
- 2023
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- View/download PDF
139. The bright side of dentistry.
- Subjects
DENTISTRY ,CARBAMIDE peroxide ,TOOTH sensitivity ,HYDROGEN peroxide - Abstract
The article focuses on Coltene's Brilliant Lumina product, designed to provide a comfortable and effective teeth-brightening treatment without causing tooth sensitivity.
- Published
- 2024
140. Lipase-mediated Baeyer–Villiger oxidation of benzylcyclopentanones in ester solvents and deep eutectic solvents.
- Author
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Mazur, Marcelina, Janeczko, Tomasz, and Gładkowski, Witold
- Subjects
- *
BAEYER-Villiger rearrangement , *EUTECTICS , *CARBAMIDE peroxide , *CHOLINE chloride , *SOLVENTS , *ESTERS - Abstract
This work presents the chemo-enzymatic Baeyer–Villiger oxidation of α-benzylcyclopentanones in ester solvents as well as deep eutectic solvents (DES). In the first part of the work the effect of selected reaction conditions on the reaction rate was determined. The oxidation process was most effective in ethyl acetate at 55 °C, with the use of lipase B from Candida antarctica immobilized on acrylic resin and UHP as oxidant. Ultimately, these preliminary studies prompted the development of an effective method for the implementation of lipase-mediated Baeyer–Villiger oxidation of benzylcyclopentanones in DES. The highest conversion was indicated when the oxidizing agent was a component of DESs (minimal DESs). The fastest conversion of ketones to lactones was observed in a mixture of choline chloride with urea hydrogen peroxide. In this case, after 3 days, the conversion of the ketones to lactones products exceeded 92% for all substrates. As a result, two new lactones were obtained and fully characterized by spectroscopic data. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
141. Quick Release of Hydrogen Peroxide from Carbamide Peroxide Promotes Apoptosis of A549 Lung Cancer Cells.
- Author
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Meng, Xiangrui, Zheng, Qiao, Sun, Yuanyuan, Wang, Qian, Wang, Lan, Yuan, Ping, Song, Xiao, and Miao, Yuqing
- Subjects
- *
CARBAMIDE peroxide , *LUNG cancer , *HYDROGEN peroxide , *APOPTOSIS , *HABER-Weiss reaction , *CANCER cells - Abstract
Lung cancer is one of the malignant tumors with the leading morbidity and mortality worldwide. H2O2 is an important oxidant, and lethal to tumor cells. The present study aimed to explore new higher‐H2O2‐content and faster‐H2O2‐release rate carbamide peroxide (CP) compounds for treatment of lung cancer. The CP added with benzoic acid termed CP−B was applied in the research. Fenton reaction was used to determine the content and rate of H2O2 release by degrading organic small molecule dyes. The results showed that CP−B could be decolorized 200 mg/L RhB solution within 60 s. The phenotype was analyzed by vitro experiment the effects of the CP compound on A549 lung cancer cell line. The results showed that CP−B had a significant effect on pro‐apoptosis, anti‐proliferation and anti‐migration of A549 cells. Using RNA seq, it was found that CP−B might up‐regulate the INS‐IGF2 gene and it was closely related to the PI3 K/AKT signaling pathway. Finally, in vivo experiments indicated that CP−B has extremely low side effects and potentially tumor treatment capabilities. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
142. Mn(III)-Porphyrin Immobilized on the Graphene Oxide-Magnetite Nanocomposite as an Efficient Heterogeneous Catalyst for the Epoxidation of Alkenes.
- Author
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Hajian, Robabeh and Bahrami, Elnaz
- Subjects
- *
HETEROGENEOUS catalysts , *CARBAMIDE peroxide , *EPOXIDATION , *ATOMIC absorption spectroscopy , *PINENE , *MANGANESE porphyrins , *GRAPHENE oxide , *ULTRAVIOLET spectrophotometry - Abstract
In this research, β-tetra-brominated meso-tetraphenylporphyrinatomanganese(III) acetate [MnTPPBr4(OAc)] (MnPor) was anchored onto a magnetite imidazole-modified graphene oxide nanosheet (Fe3O4.GO.Im). The obtained catalyst (Fe3O4.GO.Im@MnPor) was characterized through Fourier transform infrared (FT-IR) and diffuse reflectance UV–Visible spectrophotometry (DR UV–Vis), powder X-ray diffractometry (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) spectroscopy, thermogravimetric analysis (TGA) and atomic absorption spectroscopy. The characterization was performed to determine the amount of manganese porphyrin loaded on the GO support. The new immobilized catalyst was employed for the efficient epoxidation of different alkenes with urea hydrogen peroxide (UHP) and acetic acid (HOAc) as oxidant activators under mild conditions. Olefins were oxidized efficiently to their corresponding epoxide with 63–100% selectivity in the presence of Fe3O4.GO.Im@MnPor. Moreover, an remarkable turnover frequency (93) was achieved for the oxidation of α-pinene. The graphene oxide-bound Mn-porphyrin was recovered from the reaction mixture by magnetic decantation and reused several times. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
143. Influence of diet and red wine exposure on the velocity of at home bleaching: A randomized controlled clinical trial.
- Author
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MENEZES DE SOUZA, JAMILE, ALVES DA SILVA AGUIAR, JOÃO PAULO, BATISTA DAS NEVES, WASHINGTON JOSÉ, FELIPE ESPINDOLA-CASTRO, LUÍS, TENÓRIO SALVADOR DA COSTA, DAENE PATRÍCIA, and VICENTE DA SILVA, CLAUDIO HELIOMAR
- Subjects
BLEACHING (Chemistry) ,RED wines ,CLINICAL trials ,RANDOMIZED controlled trials ,TOOTH sensitivity ,CARBAMIDE peroxide - Abstract
Purpose: To evaluate the influence of diet and exposure to red wine on the treatment velocity, clinical results, postoperative tooth sensitivity, and patient satisfaction after tooth bleaching. Methods: 45 subjects undergoing home bleaching with 16% carbamide peroxide (CP) were randomly separated into three groups, depending on the restriction of colored food and the use of a red wine mouthwash. Shades of teeth I I and 21 were assessed using a digital spectrophotometer (VITA Easy Shade) at TO (before treatment). T7 (7 days after treatment), TI 5 (15 days after treatment), and T30 (30 days after treatment). The assessments were verified using the CIELab system (values of L*. a*, and b*) and the change in shade was calculated (AE, AL, Aa, and Ab). Results: No statistically significant differences in AE, AL, Aa, and Ab were found between the groups. However, at TA the group restricted from colored foods without red wine mouthwash had meaningful variations in L*, a*, and b*. Statistically, there was no difference in tooth sensitivity between the groups in the 7- and 15-day periods. Patients in the restricted colored foods without red wine mouthwash group were more satisfied after the end of treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2022
144. Phase and crystallinity regulations of Ni(OH)2 by vanadium doping boost electrocatalytic urea oxidation reaction.
- Author
-
Cao, Qiuhan, Yuan, Yahui, Wang, Kaili, Huang, Wen, Zhao, Yongjie, Sun, Xiujuan, Ding, Rui, Lin, Weiwei, Liu, Enhui, and Gao, Ping
- Subjects
- *
CARBAMIDE peroxide , *VANADIUM , *CATALYSTS , *UREA , *CARBON electrodes , *FUEL cells , *HYDROGEN evolution reactions , *MICROBIAL fuel cells - Abstract
The V doping not only regulates the phase type and degree of crystallization, but also modulates the electronic environment, generates more oxygen vacancies and more catalytic active Ni3+ species, ultimately boosting UOR performance. [Display omitted] Direct urea fuel cell (DUFC) and overall urea splitting system have attracted considerable attention as promising choice for energy conversion. Whereas, the anodic half reaction of electrocatalytic urea oxidation reaction (UOR) in these systems awfully limited their practical application due to the complex 6-electron transfer process. Herein, vanadium doped nickel (V-Ni(OH) 2) with highly efficient electrocatalytic activity toward UOR was developed by a simple coprecipitation method. The introducing of V not only promotes the phase transforming from inactive β-Ni(OH) 2 to highly active α-Ni(OH) 2 , but also simultaneously modulates the electron environment of Ni, facilitating high valence species Ni3+ generation in low overpotential, enhancing the electrocatalytic activity potent of each Ni3+ site and speeding up the electrocatalytic reaction. The optimal V-Ni(OH) 2 catalyst exhibits a summit current density of 241 mA cm−2 at 1.6 V vs. RHE, a Tafel slope of 32.15 mV dec-1, outperforming β-Ni(OH) 2 and most catalysts that tested on glassy carbon electrode. Furthermore, the assembled direct urea hydrogen peroxide fuel cell (DUPFC) offers a maximum power density of 13.4 mW cm−2 at 20 °C. This work provides an example of combing phase-regulation and electron modulation method for effective UOR electrocatalysts design. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
145. Effect of Over-The-Counter Tooth-Whitening Products on Enamel Surface Roughness and Microhardness.
- Author
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AlShehri, Abdullah, AlRefeai, Mohammad H., AlZamil, Faisal, AlOtaibi, Nawaf, and AlKinani, Yara
- Subjects
AMELOBLASTS ,SURFACE roughness ,MICROHARDNESS ,CARBAMIDE peroxide ,ENAMEL & enameling ,SODIUM bicarbonate ,CHARCOAL - Abstract
Background: To evaluate the efficacy of new over-the-counter tooth-whitening products on enamel surface roughness and microhardness. Methods: A total of 120 enamel specimens were prepared and randomly allocated into six groups. Group A was treated with 10% carbamide peroxide; Group B was immersed in distilled water; Group C was treated with hydrated silica, sodium hexametaphosphate toothpaste; Group D was treated with sodium bicarbonate; Group E was treated with 0.25% citric acid; and Group F was treated with hydrated silica, charcoal powder. Results: A, B, and D demonstrated decreased Ra, whereas Groups C, E, and F showed an increased Ra after whitening. The changes in Ra from T0 to T1 in each group was statistically significant (p < 0.001) except for Group B (p = 0.85). The groups showed decreased KHN after whitening, except for specimens in Group B (distilled water). The KHN from T0 to T1 decreased significantly for groups A, C, E, and F (p = 0.001). Significant difference was observed at T1 (p < 0.0001). Conclusion: Within the limitations of this study, it could be demonstrated that surface roughness and enamel microhardness changes were influenced by the type, composition, and exposure time of the whitening product. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
146. Effect of high-concentration bleaching agents on dentin bonding: an in vitro study.
- Author
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Phuong Trinh Nguyen, Viet Hung Hoang Nguyen, and Anh Chi Phan
- Subjects
IN vitro studies ,KRUSKAL-Wallis Test ,DENTIN ,OXIDIZING agents ,CONTINUING education units ,PEROXIDES ,TREATMENT effectiveness ,TOOTH whitening ,HYDROGEN peroxide - Abstract
The aim of this in vitro study was to evaluate the effect of high-concentration hydrogen peroxide (HP) and carbamide peroxide (CP) bleaching solutions on the dentin-resin interface and the shear bond strength (SBS) of restorative materials. A total of 56 extracted human premolars were prepared with flat dentin windows and divided into groups according to the bleaching protocol: group A, bleached with 35% HP (n = 24); group B, bleached with 35% CP (n = 24); and group C, control, no bleaching (n = 8). Groups A and B were each divided into 3 subgroups according to the time of bonding: A0 or B0, bonded immediately after bleaching (n = 8); A1 or B1, bonded 1 week after bleaching (n = 8); and A2 or B2, bonded 2 weeks after bleaching (n = 8). The specimens in group C were bonded without prior bleaching. Scanning electron microscopic analysis was conducted to evaluate the length of the resin tags at the dentin-resin interface. For SBS testing, the specimens were loaded into a universal testing machine at a crosshead speed of 0.5 mm/min. The mean resin tag lengths of groups that were bonded immediately (A0 and B0) or after a 1-week delay (A1 and B1) were significantly shorter than that of group C (P < 0.001; Kruskal-Wallis test), but the differences between the 2-week delayed bonding groups (A2 and B2) and group C were not statistically significant. The SBS values of both the 35% HP and 35% CP groups increased significantly with delayed bonding time (P < 0.05; 1-way analysis of variance). When bonding was delayed until 2 weeks after bleaching, the mean SBSs of the bleaching and control groups were not significantly different (P > 0.05; Tukey test). [ABSTRACT FROM AUTHOR]
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- 2022
147. How home bleaching agents affect the color and translucency of CAD/CAM monolithic zirconia materials.
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ALKURT, Murat, YESİL DUYMUS, Zeynep, and YILDIZ, Şeyma
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ZIRCONIUM oxide ,CARBAMIDE peroxide ,HYDROGEN peroxide ,COLOR in dentistry - Abstract
To assess the effect of 10% carbamide peroxide (CP) and 6% hydrogen peroxide (HP) home bleaching agents on the translucency and color of monolithic zirconia. Ninety disc specimens were fabricated (diameter, 10 mm) from multi-layered (ML), ultra translucent multi-layered (UTML), and super translucent multi-layered (STML) zirconia blocks at three thicknesses (0.4,1,1.5 mm) (n=5). The samples were divided into two subgroups, which were treated with 6% HP (45 min per day) or 10% CP (8 h per day) for 14 days. The color of specimens was measured before bleaching (T0) and after bleaching on the third (T3), seventh (T7), and 14th (T14) day. Color (ΔE) and translucency (TP) changes were calculated. The thickness varieties used in the samples and the bleaching agent types used created statistically significant differences only in TP and ΔE00, respectively (p<0.05). Bleaching agents can affect TP and ΔE. Patients who have zirconia restorations should be careful when using home bleaching agents. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
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148. Comparative evaluation of different access cavity designs on intracoronal bleaching of endodontically treated teeth using two different agents – An in vitro study.
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Talwar, Sonali, Mahajan, Pardeep, Bajaj, Nitika, Monga, Prashant, Marya, Pratibha, and Gandhi, Piyush
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HYDROGEN peroxide ,CARBAMIDE peroxide ,TOOTH whitening ,SPECTROPHOTOMETERS ,INCISORS - Abstract
Aim: The present in vitro study was designed to determine the effect of different access cavity designs on intracoronal bleaching of endodontically treated teeth with two different agents. Materials and Methods: Fifty selected permanent maxillary central incisors were stained. Traditional and contracted access cavity designs and two types of bleaching agents, i.e., 35% carbamide peroxide and 35 percent hydrogen peroxide were used for the study. Color measurements were performed with a spectrophotometer: before staining (T1), after staining (T2), at 7 and 14 days (T3 and T4) post bleaching. The values were calculated and subjected to the statistical analysis. Results: The results of our study showed that teeth in which traditional access cavity (TAC) was prepared had statistically significant better bleaching results with both 35% carbamide peroxide and 35% hydrogen peroxide than contracted access cavity design. Carbamide peroxide showed better results than hydrogen peroxide irrespective of the access cavity design, but difference was statistically nonsignificant. Conclusion: The present study concluded that TAC design showed better results than contracted access with both carbamide peroxide and hydrogen peroxide. Whereas, when bleaching agents were compared 35% carbamide peroxide is better than 35% hydrogen peroxide irrespective of access cavity design used. [ABSTRACT FROM AUTHOR]
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- 2022
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149. Post-modification of mesoporous silica with different nitrogenous bases for immobilization of manganese porphyrin: synthesis, characterization and catalytic activity.
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Nejabat, Fatemeh, Rayati, Saeed, Kavian, Atena, Rouhani, Farzaneh, and Amini, Mostafa M.
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BASE pairs , *MANGANESE porphyrins , *CATALYTIC activity , *MESOPOROUS silica , *CARBAMIDE peroxide ,CATALYSTS recycling - Abstract
In this study, SBA15 functionalized by imidazole or pyridine as nitrogenous bases, the novel recoverable catalysts prepared by coordinative anchoring of manganese(III) complex of meso-tetraphenyl porphyrin (MnTPP(OAc)) on the functionalized SBA15 and the hybrid catalysts fully characterized by standard methods. The catalytic efficiency of the supported catalysts was evaluated for the oxidation of sulfides and alkenes with urea hydrogen peroxide and tetrabutylammonium peroxymonosulfate as oxidant. The co-catalyst activity of imidazole and pyridine for the oxidation reactions in the presence of MnTPP(OAc) compared with each other in both homogeneous and heterogeneous systems. Our results demonstrated that the product yields of the oxidation reaction reflect the co-catalytic activities of the nitrogenous donor in the homogeneous systems, but not in heterogeneous one. The attached nitrogen bases showed a relatively similar effect on the catalytic activity of Mn-porphyrin in the oxidation reactions. The main effect of the tethered co-catalyst was observed on the reusability of the supported catalysts. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
- View/download PDF
150. The effect of different finishing polishing protocols on stain absorption and color stability of resin composite restorations.
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ISLAM, MD. SOFIQUL, AAL-FATLAH, ADIAN AHMED, ALKHAN, NOORA SALAH, A. C., SMRITI ARYAL, SADR, ALIREZA, and REHMAN, MOHAMMED MUSTAHSEN
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CARBAMIDE peroxide ,COLOR in dentistry ,ABSORPTION ,GLYCERIN - Abstract
Purpose: To evaluate the degree of stain absorption of resin composite following different finishing and polishing protocols and to evaluate the efficacy of prophylaxis paste with or without addition of carbamide peroxide to remove composite surface stain. Methods: 50 resin composite blocks were prepared using nano-hybrid composite (Filtek Z250XT) and giomer (Beautifil 11 LS). Specimens were either polished with a disk or coated with 5tli~7th generation bonding or glycerin gel. The color parameters (lightness, chroma and hue) of the specimens were measured prior to staining, and after 1 and 2 weeks of staining using a color chromometer. The composite surface stain removal capability of prophylaxis pastes with or without the addition of carbamide peroxide was evaluated before and after polishing. Results: The repeated measures ANOVA showed that composite polished with a polishing disk or coated with glycerin gel have better color stability compared to composite without any polishing or coated with 58 or 76 generation bonding materials. The prophylaxis paste was able to remove composite surface stain; however, the addition of carbamide peroxide did not show any additional benefit. The results suggested that polishing with polishing disks or coating with glycerin gel is useful for the color stability ofresin composite. [ABSTRACT FROM AUTHOR]
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- 2022
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