2,965 results on '"escape"'
Search Results
152. Atrioventricular (AV) Block
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Petty, Brent G. and Petty, Brent G.
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- 2020
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153. The Black Sensible: escape routes for performances
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José Juliano Gadelha
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Art ,Escape ,Performance ,Black ,Sensible ,Drama ,PN1600-3307 ,Dramatic representation. The theater ,PN2000-3307 - Abstract
The article forges the principle of escape to think of the poetics of the body disappearance that encounter, in what the author calls fugitive performance, a way of making alive the modes of existence, which would be destined, by the reproductive futurism of the esthetical norm, to disappear and, consequently, to die. In a dialogue with Black Studies, anti-colonial criticism and my own thought on the sensitive field, the article traces the threads that expose the programs of re-theorization, representation, abstraction and performance underlying the traffic of the becoming-black in the arts.
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- 2022
154. Availability of opioid agonist treatment and critical incidents in Forensic Clinics for Dependency Diseases in Germany
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Sven Reiners, Annette Opitz-Welke, Norbert Konrad, and Alexander Voulgaris
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opioid agonist treatment ,critical incidents ,escape ,violent behavior ,forensic psychiatry ,Psychiatry ,RC435-571 - Abstract
BackgroundPrevalence of substance use disorders, especially opioid use disorders, is high in patients admitted into forensic psychiatric settings. Opioid agonist treatment is a safe, well-established, and effective treatment option for patients that suffer from opioid dependence. Surprisingly, data on the availability and practice of opioid agonist treatment (OAT) options in German Forensic Clinics for Dependency Diseases is rare. Furthermore, essential data on the prevalence of critical incidents such as violent behavior, relapse, or escape from the clinic are missing for this particular treatment setting.Materials and methodsWe conducted an observational study on all forensic addiction treatment units in Germany (Sect. 64 of the German Criminal Code). A questionnaire on the availability and practice of OAT was sent to all Forensic Clinics for Dependency Diseases in Germany. Following items were assessed: availability and the total number of patients that received an OAT in 2018, available medication options, specific reasons for start and end of OAT, number of treatments terminated without success, number of successful treatments, and critical incidents such as violent behavior, relapse, escape and reoffending. We compared the forensic clinics that offered OAT with those that did not offer this treatment option. The data were analyzed descriptively. Mean and standard deviation was calculated for metric scaled variables. For categorical variables, absolute and relative frequencies were calculated. The two groups (OAT vs. Non-OAT institutions) were compared concerning the given variables by either using Fishers exact test (categorical variables), t-test (normally distributed metric variables), or Wilcoxon-test (metric variables not normally distributed).ResultsIn total, 15 of 46 Forensic Clinics for Dependency Diseases participated in the study (33%). In total, 2,483 patients were treated in the participating clinics, 18% were relocated into prison due to treatment termination, and 15% were discharged successfully in 2018. 275 critical incidents were reported: violence against a patient (4%), violence against staff (1.6%), escape (4.7%) and reoffending in (0.5%). In seven clinics treating 1,153 patients, an OAT was available. OAT options in forensic clinics were buprenorphine/naloxone, buprenorphine, methadone, and levomethadone. Regarding critical incidents and successful discharge, no differences were detected in the clinics with or without an OAT. In the clinics that offered an OAT, we found a significantly higher rate of treatment termination without success (p < 0.007) in comparison to clinics without an OAT program. Ninety-nine patients received an OAT, and this treatment was ended due to illegal drug abuse (57%), refusal to give a urine drug sample (71%), and cases where the OAT was given away to other patients (85%).ConclusionIn Forensic Clinics for Dependency Diseases in Germany, OAT is not available in every institution, and thus, access is limited. Critical incidents such as violent behavior against staff or patients and escape are not uncommon in these forensic treatment settings. Further studies are needed to enhance the understanding of OAT practice and the risks for patients and staff.
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- 2022
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155. From escape to seeking: understanding drug tourists.
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Bingöl, Serhat
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DRUGS ,TOURISTS ,ETHNOLOGY - Abstract
Studying the relations between travel, daily life, and drugs will help understand why these tourists use drugs. Hence, the article aims to explore the social behaviors that shape the reasons and causes tourists to use drugs while traveling to a destination. For this purpose, unstructured interview and participant observation techniques were used in the study, applying the ethnography research approach. In this context, data were collected in Thailand, Cambodia, Malaysia, Indonesia, and Turkey as drug destinations between 2016 and 2020. Accordingly, while drug use in daily life is for escaping from daily life and recreational purposes, drug use while traveling occurs within the pursuit of happiness. As a result of their pursuit of happiness, drug tourists (as neo tribes) engage in social behaviors such as building strong social relations, feeling a sense of freedom, being in an entertaining atmosphere, and living the local culture. As a result, drug tourists see travel as a process from escape to seeking. [ABSTRACT FROM AUTHOR]
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- 2022
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156. العودة الی كنت والهروب من ه يغل: أبعاد وأ فاق الفلسفة بعد موت هيغل
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نوزاد جمال حمەفرج
- Abstract
After the death of Hegel, philosophy (idealism) was affected by transformations and new questions that arose due to the development in science. One of the reasons philosophers were challenged was their attitudes toward science. Hence the call to return to 'Kant'. But if we ask here: What does return to 'Kant' mean? Did he become old or forgotten after his death, especially after Hegel's dominance of the philosophical space? Or that his philosophy was and still is one of the philosophical pillars, not only within the scope of German philosophy alone but within modern philosophy as a whole. Therefore, the research discusses the dimensions of the return to the philosophy of 'Kant' and its new appearance, which opened new horizons in the history of philosophy. 'Kant' has been influential and inspiring to many of Heglian's later philosophers. Note that one of the connotations of return means that 'you' was an indispensable reference. As for the other indication, it does not exceed. That is, it does not precede it easily and does not become obsolete in some way. On the other hand, there is a call to return to Hegel in different contexts and stages as well. Therefore, the return discourse does not concern 'I was alone, but there are objective and subjective motives that motivate researchers to return to them. One of the motives, for example, is the attitude of both philosophers towards science and the adoption of the scientific view in philosophical thinking. [ABSTRACT FROM AUTHOR]
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- 2022
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157. Von der Theorie zur Begegnung.
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Hagehülsmann, Ute
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PSYCHOTHERAPISTS , *PSYCHOTHERAPY , *REFUGEES , *TRANSPERSONAL psychology - Abstract
This article shows that the use of transanalytical concepts can make sense even in times of existential threats, and that they can contribute to understand traumatizing incidents and that they can frame encounters with traumatized people. Moreover it contains transanalytical methods that can help to give stability for human brings that had to bear extremely hard situations in the direct past. The article is based on conversations with two transactional Ukrainian psychotherapists who fled from Ukraine for Germany and now offer online and onsite transactional psychotherapy to clients in Ukraine as well as for other refugees. [ABSTRACT FROM AUTHOR]
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- 2022
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158. PRIMENA FUNKCIONALNOG KOMUNIKACIONOG TRENINGA ZA REDUKCIJU PROBLEMATIČNIH PONAŠANJA U FUNKCIJI IZBEGAVANJA ZADATKA.
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Arsić, Bojana, Gajić, Anja, and Vidojković, Sara
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Copyright of Pedagogical Reality / Pedagoška Stvarnost is the property of University of Novi Sad, Faculty of Philosophy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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159. Der Flüchtling - ein literarischer Topos.
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WOLTING, MONIKA
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Copyright of Porównania / Comparisons. A Journal on Comparative Literature & Interdisciplinary Studies is the property of Adam Mickiewicz University Poznao, Press of "Poznanskie Studia Polonistyczne" and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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160. Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines and Therapeutic Antibodies.
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Miller, Nathaniel L., Raman, Rahul, Clark, Thomas, and Sasisekharan, Ram
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QUATERNARY structure ,IMMUNOGLOBULINS ,VIRAL antigens ,ANTIBODY formation ,EPITOPES - Abstract
The dynamic interplay between virus and host plays out across many interacting surfaces as virus and host evolve continually in response to one another. In particular, epitope-paratope interactions (EPIs) between viral antigen and host antibodies drive much of this evolutionary race. In this review, we describe a series of recent studies examining aspects of epitope complexity that go beyond two interacting protein surfaces as EPIs are typically understood. To structure our discussion, we present a framework for understanding epitope complexity as a spectrum along a series of axes, focusing primarily on 1) epitope biochemical complexity (e.g., epitopes involving N-glycans) and 2) antigen conformational/dynamic complexity (e.g., epitopes with differential properties depending on antigen state or fold-axis). We highlight additional epitope complexity factors including epitope tertiary/quaternary structure, which contribute to epistatic relationships between epitope residues within- or adjacent-to a given epitope, as well as epitope overlap resulting from polyclonal antibody responses, which is relevant when assessing antigenic pressure against a given epitope. Finally, we discuss how these different forms of epitope complexity can limit EPI analyses and therapeutic antibody development, as well as recent efforts to overcome these limitations. [ABSTRACT FROM AUTHOR]
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- 2022
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161. How Positive and Negative Environmental Behaviours Influence Sustainable Tourism Intentions.
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Shien, Li-Yao, Liu, Chih-Hsing, and Li, Yi-Min
- Abstract
This study developed and examined a theoretical model of moderated mediation in which positive and negative environmental behaviours (e.g., attitudes, destruction, conservation, and eco-friendliness) serve as a moderating mechanism that explains the link between the two critical mediating effects of escape and sustainable experiences on revisit intentions. The results of a study of 483 foreign tourists provide support for our hypothesized model. First, the results showed that motivations have indirect and positive effects on revisit intentions through sustainable experiences and escape-seeking. Second, the moderating effects of positive environmental behaviours were found to be positive, while negative environmental behaviours had negative effects on the dimensions of escape and experience on revisit intentions for sustainable tourism. Third, we discussed how this interesting pattern of the moderated mediation setting could be explained by using the theoretical background and considering previous studies on sustainable tourism. [ABSTRACT FROM AUTHOR]
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- 2022
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162. Enrichment model of shale gas in southeastern Sichuan Basin: a case study of Upper Ordovician Wufeng and Lower Silurian Longmaxi formations in Dingshan area
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Kai NI, Mingfa WANG, and Xiang LI
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horizontal migration ,enrichment ,escape ,shale gas ,wufeng-longmaxi formations ,dingshan area ,sichuan basin ,Geophysics. Cosmic physics ,QC801-809 ,Geology ,QE1-996.5 - Abstract
Based on the understanding of the basic geological conditions of shale gas from the Upper Ordovician Wufeng Formation to the Lower Silurian Longmaxi Formation in Dingshan area of the southeastern Sichuan Basin, the occurrence, migration mode and intensity of natural gas in the shale gas system were discussed according to the results of drilling, logging, fracturing test, laboratory test and structural interpretation, moreover, a shale gas enrichment mode suitable for the study area was proposed. In shale gas systems, high-angle fractures extend for a short distance, while horizontal fractures such as bedding-parallel detachment and interlayer bedding fractures extend for a long distance. As a result, the permeability in the bedding direction is much greater than that in the vertical direction. These characteristics together determined that natural gas in shale gas system was usually transported horizontally, and sometimes both horizontally and vertically. For the Qiyueshan fault zone, the burial depth of shale reservoir and the distance to Qiyueshan fault zone are the major constrains for shale gas enrichment in the Wufeng-Longmaxi formations in the study area. The Qiyueshan fault zone is a basin-controlling fault zone with fractures and associated fractures developed, and is a shale gas escaping area. In the shallow-buried area in the southeastern part, high-angle fractures were relatively developed, by which horizontal fractures were opened. The proportion of free gas was less than 60%. A normal pressure system indicates a semi-retention area for shale gas. In the middle-to deep-buried area in the northwest, high-angle fractures were relatively undeveloped, and horizontal fractures were closed. The vertical and horizontal migrations were blocked, and most of shale gas was trapped in shale reservoirs. The proportion of free gas is more than 60%. A high-to ultra-high pressure system indicates a shale gas accumulation area.
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- 2021
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163. Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines and Therapeutic Antibodies
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Nathaniel L. Miller, Rahul Raman, Thomas Clark, and Ram Sasisekharan
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epitope ,paratope ,glycoepitope ,antibody ,escape ,SARS-CoV-2 ,Immunologic diseases. Allergy ,RC581-607 - Abstract
The dynamic interplay between virus and host plays out across many interacting surfaces as virus and host evolve continually in response to one another. In particular, epitope-paratope interactions (EPIs) between viral antigen and host antibodies drive much of this evolutionary race. In this review, we describe a series of recent studies examining aspects of epitope complexity that go beyond two interacting protein surfaces as EPIs are typically understood. To structure our discussion, we present a framework for understanding epitope complexity as a spectrum along a series of axes, focusing primarily on 1) epitope biochemical complexity (e.g., epitopes involving N-glycans) and 2) antigen conformational/dynamic complexity (e.g., epitopes with differential properties depending on antigen state or fold-axis). We highlight additional epitope complexity factors including epitope tertiary/quaternary structure, which contribute to epistatic relationships between epitope residues within- or adjacent-to a given epitope, as well as epitope overlap resulting from polyclonal antibody responses, which is relevant when assessing antigenic pressure against a given epitope. Finally, we discuss how these different forms of epitope complexity can limit EPI analyses and therapeutic antibody development, as well as recent efforts to overcome these limitations.
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- 2022
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164. Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization
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Mimi Q La-Vu, Ekayana Sethi, Sandra Maesta-Pereira, Peter J Schuette, Brooke C Tobias, Fernando MCV Reis, Weisheng Wang, Anita Torossian, Amy Bishop, Saskia J Leonard, Lilly Lin, Catherine M Cahill, and Avishek Adhikari
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periaqueductal gray ,predator ,escape ,fear ,optogenetics ,cholecystokinin ,Medicine ,Science ,Biology (General) ,QH301-705.5 - Abstract
During threat exposure, survival depends on defensive reactions. Prior works linked large glutamatergic populations in the midbrain periaqueductal gray (PAG) to defensive freezing and flight, and established that the overarching functional organization axis of the PAG is along anatomically-defined columns. Accordingly, broad activation of the dorsolateral column induces flight, while activation of the lateral or ventrolateral (l and vl) columns induces freezing. However, the PAG contains diverse cell types that vary in neurochemistry. How these cell types contribute to defense remains unknown, indicating that targeting sparse, genetically-defined populations may reveal how the PAG generates diverse behaviors. Though prior works showed that broad excitation of the lPAG or vlPAG causes freezing, we found in mice that activation of lateral and ventrolateral PAG (l/vlPAG) cholecystokinin-expressing (CCK) cells selectively caused flight to safer regions within an environment. Furthermore, inhibition of l/vlPAG-CCK cells reduced predator avoidance without altering other defensive behaviors like freezing. Lastly, l/vlPAG-CCK activity decreased when approaching threat and increased during movement to safer locations. These results suggest CCK cells drive threat avoidance states, which are epochs during which mice increase distance from threat and perform evasive escape. Conversely, l/vlPAG pan-neuronal activation promoted freezing, and these cells were activated near threat. Thus, CCK l/vlPAG cells have opposing function and neural activation motifs compared to the broader local ensemble defined solely by columnar boundaries. In addition to the anatomical columnar architecture of the PAG, the molecular identity of PAG cells may confer an additional axis of functional organization, revealing unexplored functional heterogeneity.
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- 2022
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165. Escaping the past and living in the present: a qualitative exploration of substance use among Syrian male refugees in Germany
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Jutta Lindert, Ulrike Neuendorf, Marta Natan, and Ingo Schäfer
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Trauma ,Mental health ,Qualitative research ,Refugee populations ,Substance use ,Escape ,Special situations and conditions ,RC952-1245 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background Syrians have been the largest group of refugees in Germany since 2014. Little is known about Syrian refugees` perspectives on substance use. The aim of this study is to investigate the perspective of male refugees from Syria and to foster specific knowledge and understanding of substance use. Methods We applied a qualitative study design. Five semi-structured focus group discussions with a total of 19 refugees were conducted in 2019 among the difficult to reach population of Syrian refugees. Audio recordings were translated and transcribed. We used a hybrid approach by integrating inductive and deductive thematic frameworks. Results We identified common themes. Firstly, refugees perceived that substances are widely available and accepted in Germany. Secondly, refugees perceived that rules and norms in Germany differ from rules and norms in the home country and favor availability of substances. Thirdly, substance use is related to the intention to escape the past. Fourthly, substance use is related to living in the present through connecting with others and being part of the community. Finally, mental health professional treatment for substance use is associated with shame. Conclusions Findings support Syrian refugees` perspectives of substance use as a way of both escaping the past and coping with psychosocial difficulties in the present in a socio-ecological understanding. Understanding the explanatory model of Syrian refugees can inform future interventions to prevent substance abuse and design tailored interventions. Further studies with Syrian refugees in more countries are needed to better understand resettled refugees` perspectives on substance use.
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- 2021
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166. بنية الزمن في كونكان المجموعة القصصية لـ سعد محمد رحيم The structure of time in konkan for Mohamed Said Rahim
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نوره عباس علي Noora Abbas Ali and فرحان بدري الحربي Farhan Bedri Al-Harbi
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البنية ، الزمن، الانتظار، الهروب ,structure ,time ,waiting ,escape ,Fine Arts ,History (General) and history of Europe - Abstract
The research aims to reveal the structure of time that was evident throughout the narrative discourse. That rebellious structure and effective in embodying the life beliefs of the narrative subjects with acceptance and harmony. She came carrying between her two hands the two swinging dimensions of the human soul, namely (flight and waiting), which are the problems of eternal perception. The two themes associated with non-existence and non-existence, the extent of the ability to manifest and hide with the present moment data. . Psychological time, with its representations, constituted the controlling and controlling power of the narrative structure, so the narrative text tried to throw all the existential questions that cause anxiety, turmoil and alienation leading to flight or confrontation and indifference to the terrifying absurdity of the convulsions of memory, dreams, visions, and lost in the circle of the future without an answer. . The collection of stories / Konkan included (18 stories) distributed between long and short. It has an integrated comprehensive format, with its repeated and linked coincidences. We, through our critical analysis of the structure of time, are not going to commit to the critical data of the efforts of previous theorists of this structure in the conceptual and theoretical context of it, but rather we will employ what fits the structural context of the narrative texts. As our study focuses on the structure of psychological time, a linguistic statistical study, with its most prominent excavations (flight time) and (time waiting) without searching for the institutional framework for the narrative product. We divided the research into two topics. In the first, we searched for the concept of structure in its linguistic and critical connotation and the structure of time in the orbit, critical and psychological research, while the second research examined the representations of the adulterous structure represented by temporal flight and waiting time, and the conclusion in which we reached the most important results.
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- 2021
167. Escape and absconding among offenders with schizophrenia spectrum disorder – an explorative analysis of characteristics
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Johannes Kirchebner, Steffen Lau, and Martina Sonnweber
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Absconding ,Escape ,Schizophrenia ,Offending ,Machine learning ,Forensic psychiatry ,Psychiatry ,RC435-571 - Abstract
Abstract Background Escape and absconding, especially in forensic settings, can have serious consequences for patients, staff and institutions. Several characteristics of affected patients could be identified so far, albeit based on heterogeneous patient populations, a limited number of possible factors and basal statistical analyses. The aim of this study was to determine the most important characteristics among a large number of possible variables and to describe the best statistical model using machine learning in a homogeneous group of offender patients with schizophrenia spectrum disorder. Methods A database of 370 offender patients suffering from schizophrenia spectrum disorder and 507 possible predictor variables was explored by machine learning. To counteract overfitting, the database was divided into training and validation set and a nested validation procedure was used on the training set. The best model was tested on the validation set and the most important variables were extracted. Results The final model resulted in a balanced accuracy of 71.1% (95% CI = [58.5, 83.1]) and an AUC of 0.75 (95% CI = [0.63, 0.87]). The variables identified as relevant and related to absconding/ escape listed from most important to least important were: more frequent forbidden intake of drugs during current hospitalization, more index offences, higher neuroleptic medication, more frequent rule breaking behavior during current hospitalization, higher PANSS Score at discharge, lower age at admission, more frequent dissocial behavior during current hospitalization, shorter time spent in current hospitalization and higher PANSS Score at admission. Conclusions For the first time a detailed statistical model could be built for this topic. The results indicate the presence of a particularly problematic subgroup within the group of offenders with schizophrenic spectrum disorder who also tend to escape or abscond. Early identification and tailored treatment of these patients could be of clinical benefit.
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- 2021
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168. A Review of the Evolution and Trends in Research on the Emergency Evacuation of Urban Underground Spaces
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Caiyun Cui, Qianwen Shao, Yong Liu, Guobo Han, Feng Liu, and Xiaowei Han
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evacuation ,underground space ,escape ,Web of Science ,knowledge map ,visualized analysis ,Building construction ,TH1-9745 - Abstract
In recent decades, there has been a significant proliferation of literature pertaining to the evacuation of urban underground spaces. However, few studies have focused on scientometric reviews that identify research topics, evolution patterns, and trends in this field. To bridge this gap, the present study adopted a bibliometric approach by searching the literature related to underground space evacuations in the Web of Science (WOS) core database for the period 1992–2022, from which we visualized and analyzed the issuance status of the country, author, and institution, as well as the cooperation status, using Citespace software. The findings of this paper are as follows: First, there has been a consistent upward trend in the quantity of literature within this field over time. Second, Swedish authors and institutions have made important contributions to the advancement of research in this area. Third, the current research topics are concentrated on themes such as modeling and simulation, smoke control methods, integrative research on factors affecting pedestrian evacuation behavior, pedestrian walking speed under smoke-filled conditions, and the influence of wayfinding devices on exit selection/wayfinding. Finally, to advance the safety in underground spaces, future research trends should include improving basic data, refining simulation model parameters, assessing the evacuation capabilities of special populations, examining the impact of risk perception on evacuation behavior, and conducting specific research on the different risks in underground spaces. The findings may contribute to the managerial development of more comprehensive and effective emergency plans for underground spaces, thereby enhancing the survival rates and safety of pedestrians during disasters or other emergencies.
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- 2023
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169. Analysis of Photo-Generated Carrier Escape in Multiple Quantum Wells
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Jiaping Guo, Weiye Liu, Ding Ding, Xinhui Tan, Wei Zhang, Lili Han, Zhaowei Wang, Weihua Gong, Jiyun Li, Ruizhan Zhai, Zhongqing Jia, Ziguang Ma, Chunhua Du, Haiqiang Jia, and Xiansheng Tang
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photo-generated carriers ,escape ,uncertainty principle ,Crystallography ,QD901-999 - Abstract
Recent experiments have shown that more than 85% of photo-generated carriers can escape from multiple quantum wells (MQWs) sandwiched between p-type and n-type layers (PIN). In this work, we quantitatively analyze the relationship between the energy of carriers and the height of potential barriers to be crossed, based on the GaAs/InGaAs quantum well structure system, combined with the Heisenberg uncertainty principle. It was found that that the energy obtained by electrons from photons is just enough for them to escape, and it was found that the energy obtained by the hole is just enough for it to escape due to the extra energy calculated, based on the uncertainty principle. This extra energy is considered to come from photo-generated thermal energy. The differential reflection spectrum of the structure is then measured by pump–probe technology to verify the assumption. The experiment shows that the photo-generated carrier has a longer lifetime in its short circuit (SC) state, and thus it possesses a lower structure temperature than that in open circuit (OC). This can only explain a thermal energy reduction caused by the continuous carrier escape in SC state, indicating an extra thermal energy transferred to the escaping carriers. This study is of great significance to the design of new optoelectronic devices and can improve the theory of photo-generated carrier transports.
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- 2023
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170. Locus coeruleus noradrenaline depletion and its differential impact on CO2-induced panic and hyperventilation in male and female mice.
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Ripamonte, Gabriel C., Fonseca, Elisa M., Frias, Alana T., Patrone, Luis Gustavo A., Vilela-Costa, Heloísa H., Silva, Kaoma S.C., Szawka, Raphael E., Bícego, Kênia C., Zangrossi Jr, Hélio, Plummer, Nicholas W., Jensen, Patricia, and Gargaglioni, Luciane H.
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LOCUS coeruleus , *NORADRENALINE , *HYPERVENTILATION , *STARTLE reaction , *PANIC attacks , *CARBON dioxide - Abstract
CO 2 exposure has been used to investigate the panicogenic response in patients with panic disorder. These patients are more sensitive to CO 2 , and more likely to experience the "false suffocation alarm" which triggers panic attacks. Imbalances in locus coeruleus noradrenergic (LC-NA) neurotransmission are responsible for psychiatric disorders, including panic disorder. These neurons are sensitive to changes in CO 2 /pH. Therefore, we investigated if LC-NA neurons are differentially activated after severe hypercapnia in mice. Further, we evaluated the participation of LC-NA neurons in ventilatory and panic-like escape responses induced by 20% CO 2 in male and female wild type mice and two mouse models of altered LC-NA synthesis. Hypercapnia activates the LC-NA neurons, with males presenting a heightened level of activation. Mutant males lacking or with reduced LC-NA synthesis showed hypoventilation, while animals lacking LC noradrenaline present an increased metabolic rate compared to wild type in normocapnia. When exposed to CO 2 , males lacking LC noradrenaline showed a lower respiratory frequency compared to control animals. On the other hand, females lacking LC noradrenaline presented a higher tidal volume. Nevertheless, no change in ventilation was observed in either sex. CO 2 evoked an active escape response. Mice lacking LC noradrenaline had a blunted jumping response and an increased freezing duration compared to the other groups. They also presented fewer racing episodes compared to wild type animals, but not different from mice with reduced LC noradrenaline. These findings suggest that LC-NA has an important role in ventilatory and panic-like escape responses elicited by CO 2 exposure in mice. • Hypercapnia activates the LC-NA neurons, with males presenting a heightened level of activation. • Mutant males lacking or with reduced LC-NA synthesis showed hypoventilation. • Mutant males lacking LC-NA systhesis had a lower respiratory frequency, while mutant females showed a higher tidal volume under CO 2. • Mice lacking LC noradrenaline had a blunted jumping response and an increased freezing duration compared to the other groups. [ABSTRACT FROM AUTHOR]
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- 2024
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171. Diffusion limited escape of hydrogen from Mars.
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Yelle, Roger V.
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MARS (Planet) , *BALLISTIC conduction , *COLD (Temperature) , *HYDROGEN ,COLD regions - Abstract
Hydrogen escapes from Mars primarily by the Jeans mechanism but the rate is variable and the controlling factors complicated. One of the complications is that the temperature at the Martian exobase varies from ∼ 100 K in the early morning hours to ∼ 300 K in the afternoon. At the cold temperatures on the nightside of Mars, H escape rate is limited by Jeans escape, but on the warm dayside H escape is limited by the diffusion rate through the thermosphere. Nevertheless, the hot and cold regions are coupled by efficient ballistic transport through the exosphere. Because of this, H diffuses upward at the diffusion-limited rate even on the nightside and, once H reaches the exosphere, it is transported rapidly by ballistic flow to the warm dayside, where it escapes. As a result, escape is not at all limited by the cold regions of the exobase. The globally integrated escape flux is equal to the globally integrated diffusive limit. Because of this it is important to precisely calculate the diffusion-limited flux and we present a new formulation that is more accurate than the classical formula. • A new, more accurate, formulation of the diffusion-limited flux for an escaping species is provided. • The exospheric temperature on Mars spans the range at which hydrogen escape is kinetically limited to diffusion limited. • Efficient ballistic transport through the exosphere results in a strong day-night flow of hydrogen. • Because of the ballistic flow, the upward transport of H on Mars is diffusion limited on the nightside despite the low temperatures. • The globally integrated H escape rate is equal to the globally integrated diffusion limit. [ABSTRACT FROM AUTHOR]
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- 2024
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172. How often and under what circumstances do escapes from prison and jail result in violence? An examination of the "powder keg" theory.
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Peterson, Bryce E. and Mellow, Jeff
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VIOLENCE ,PRISONS ,IMPRISONMENT ,JAILS ,CRIME prevention - Abstract
Little research has examined the "powder keg" theory (that escapes are inherently violent), which has been used in U.S. courts to apply sentencing enhancements to people convicted of escaping. We examine open-source data on 610 escapees from jails and prisons to understand the prevalence and scope of escape-related violence, and the relationship between theoretically relevant covariates and these outcomes. Though our data is not representative of all U.S. escapes, we found that 19.2% of the incidents in our sample resulted in violence, with more violence occurring at the breakout (10.9%) than in the community (8.4%) or during recapture (5.7%). Escapees were more likely to use violence when they were in secure custody or outside the facility, if they fled during morning or evening hours, or if they were incarcerated in a jail rather than a lower security prison. These findings yield numerous implications for theory, policy, and practice. [ABSTRACT FROM AUTHOR]
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- 2024
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173. Assessing the Condition of Complex Poly-Material Artworks by Py-GC-MS: The Study of Cellulose Acetate-Based Animation Cels.
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Izzo, Francesca Caterina, Van Keulen, Henk, and Carrieri, Alessandra
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ACRYLIC paint , *ACRYLIC painting , *CELLULOSE , *CELLULOSE acetate , *CONSERVATION & restoration , *GAS chromatography/Mass spectrometry (GC-MS) , *PHTHALATE esters - Abstract
The material composition of a group of Rodovetri, hand-painted animation cels, made in the 1950s and 1960s for Italian television, has been determined by Flash Py-GC-MS, Thermally assisted Hydrolysis and Methylation-(Py-)GC-MS and GC-MS investigations, where, for the pyrolysis applications, the pyrolyzer is connected septum-less to the GC inlet. The condition of the selected animation cels was generally poor (yellowing, exudation, warping, cracking). The cels are made of plasticized cellulose acetate (CA) and decorated with alkyd paint. Exudating plasticizers from the CA support migrated into the paint; this has softened the paint layers and made the cels stick together. CA is known to be very unstable and easily subjected to degradation, which cannot be reversed, only slowed down by preventive conservation. Most of the cels are plasticized with bis(2-methoxyethyl) phthalate (DMEP) and triphenyl phosphate (TPP). The research shows a relationship between the degradation of CA and the presence of TPP and DMEP. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
174. Reappraising the Production and Transfer of Hydrogen Atoms From the Middle to the Upper Atmosphere of Mars at Times of Elevated Water Vapor.
- Author
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Montmessin, F., Belyaev, D. A., Lefèvre, F., Alday, J., Vals, M., Fedorova, A. A., Korablev, O. I., Trokhimovskiy, A. V., Chaffin, M. S., and Schneider, N. M.
- Subjects
UPPER atmosphere ,MARTIAN atmosphere ,MIDDLE atmosphere ,ABSTRACTION reactions ,HYDROGEN production ,OIL field flooding ,WATER vapor - Abstract
Water escape on Mars has recently undergone a paradigm shift with the discovery of unexpected seasonal variations in the population of hydrogen atoms in the exosphere where thermal escape occurs and results in water lost to space. This discovery led to the hypothesis that, contradicting the accepted pathway, atomic hydrogen in the exosphere was not only produced by molecular hydrogen but mostly by high altitude water vapor. Enhanced presence of water at high altitude during southern spring and summer, due to atmospheric warming and intensified transport, favors production of H through photon‐induced ion chemistry of water molecules and thus appears to be the main cause of the observed seasonal variability in escaping hydrogen. This hypothesis is supported by the observation of large concentrations of water vapor between 50 and 150 km during the southern summer solstice and global dust events. Using a simplified yet representative air parcel transport model, we show that in addition to the formation of atomic hydrogen from water photolysis above 80 km, a major fraction of the exospheric hydrogen is formed at altitudes as low as 60 km and is then directly advected to the upper atmosphere. Comparing the injection modes of a variety of events (global dust storm, perihelion periods, and regional storm), we conclude that southern spring/summer controls H production and further ascent into the upper atmosphere on the long term with direct implication for water escape. Plain Language Summary: Numerous lines of evidence suggest that Mars' water inventory was much larger in the past than it is today. The loss of this inventory has been driven by the formation of hydrated minerals on the surface, as well as by the escape of water to space. The first part of the escape process comprises the formation of H atoms, which may escape the planet once they reach the uppermost layers of the atmosphere. Here, we investigate one mechanism by which the H atoms may reach these high altitudes: the breakdown of water molecules by solar ultraviolet photons in the middle atmosphere (60–70 km above the surface), and the posterior ascent of the newly formed H atoms to the upper altitudes. We use a model that reveals that this process is the dominant contributor of atomic H to the upper atmosphere during periods of strong atmospheric circulation. In particular, we find that this mechanism is most efficient during the spring/summer season in the Southern Hemisphere, when Mars is closest to the Sun. Given that this season occurs every Martian year, our calculations suggest that this process has been the dominant contributor to water escape in the long term. Key Points: We decipher hydrogen production and migration to Mars' upper atmosphere using a box model for a variety of elevated water vapor casesH atoms formed between 60 and 80 km supply a dominant fraction of hydrogen to the upper atmosphereOur results suggest that perihelion climate has a key role in the hydrogen transfer to the upper atmosphere overall [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
175. VIEWING POSTMODERN AMERICAN YOUTH SOCIETY THROUGH UGLIES AND THE HUNGER GAMES: A TURN FROM NOSTALGIA TO ESCAPE.
- Author
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Sriastuti, Anna
- Subjects
- *
TRANSPORTATION , *GLOBALIZATION , *FINANCIAL crises , *POSTMODERNISM (Literature) - Abstract
At the turn of the 21st century, Americans experienced the shift from the Modern Era to the Postmodern Era. The Modern Era that worships technology blurs the borders between countries. Technology and transportation, as the major components of the revolution in the globalization era, have labeled the planet a 'global world'. This study found out that the Internet, for instance, has made access among countries possible. One of the effects of this movement towards globalization is the erosion of American exclusivity. Apart from its positive contributions to the world, technology has produced world chaos and destruction. The attacks on the World Trade Center and Pentagon in 2001 and the economic crisis in 2008 are two fatal catastrophes that hit America in the 21st century and caused major trauma to the American people. This study is conducted to analyze postmodern American youth society through the analysis of Uglies and The Hunger Games to see how American youth make a turn from a victorious nostalgia to an escape from reality and create their own imaginary worlds through dystopian literature in response to what is happening in America. Using the theories of Postmodernism, small narratives from the data of the two novels are collected to reveal what are implicitly stated in the two novels. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
176. Particles and Photons as Drivers for Particle Release from the Surfaces of the Moon and Mercury.
- Author
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Wurz, P., Fatemi, S., Galli, A., Halekas, J., Harada, Y., Jäggi, N., Jasinski, J., Lammer, H., Lindsay, S., Nishino, M. N., Orlando, T. M., Raines, J. M., Scherf, M., Slavin, J., Vorburger, A., and Winslow, R.
- Subjects
- *
LUNAR surface , *MERCURY (Planet) , *PHOTONS , *PLANETARY surfaces , *METEOROIDS - Abstract
The Moon and Mercury are airless bodies, thus they are directly exposed to the ambient plasma (ions and electrons), to photons mostly from the Sun from infrared range all the way to X-rays, and to meteoroid fluxes. Direct exposure to these exogenic sources has important consequences for the formation and evolution of planetary surfaces, including altering their chemical makeup and optical properties, and generating neutral gas exosphere. The formation of a thin atmosphere, more specifically a surface bound exosphere, the relevant physical processes for the particle release, particle loss, and the drivers behind these processes are discussed in this review. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
177. УПОТРЕБА ВАТРЕНОГ ОРУЖЈА ПРЕМА ОСУЂЕНОМ У СЛУЧАЈУ БЕКСТВА.
- Author
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Дракић, Драгиша С. and Милић, Иван Д.
- Subjects
- *
FIREARMS , *PRISONS , *CRIMINALS , *ATTENTION , *AUTHORS - Abstract
The use of firearms is the most severe means of coercion that may be employed against a convict. The legal acts regulating the execution of criminal sanctions also foresee the use of firearms as means of coercion. The authors’ attention is the use of firearms against a convict in the case of escape from a penitentiary. The authors highlight, first and foremost, who and under what conditions may employ a firearm against a convict. The relevant legal acts are analyzed and adequate and deficient solutions concerning the use of firearms are identified. The authors suggest de lege ferenda solutions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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178. Fluchtmigration und Arbeitsmarktintegration
- Author
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Struck, Olaf, Berufsverband Deutscher Soziologinnen und Soziologen e.V., Blättel-Mink, Birgit, editor, Noack, Torsten, editor, Onnen, Corinna, editor, Späte, Katrin, editor, and Stein-Redent, Rita, editor
- Published
- 2019
- Full Text
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179. Conditional role of parental controlling mediation on the relationship between escape, daily game time, and gaming disorder
- Author
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Görgülü, Zeynep and Özer, Arif
- Published
- 2023
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180. Niepokojący wizerunek konia na wybranych przykładach literatury niemieckojęzycznej – symbolika i znaczenie
- Author
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Estera Głuszko-Boczoń
- Subjects
horse ,anxiety ,death ,elements ,crisis ,escape ,Zoology ,QL1-991 ,History of scholarship and learning. The humanities ,AZ20-999 - Abstract
Literature usually represents a horse as a loyal companion of a man, a noble and intelligent animal. The image of a horse in some works, however, relies on their mystery, it evokes anxiety, fear. It symbolizes an internal unease or a drive to escape. Sometimes a horse is equated to the messenger of death; it personifies dark, incomprehensible forces that cannot be understood by a human mind. This aspect of the unexplored equine nature in Germanlanguage literature is addressed in this study.
- Published
- 2020
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181. Slavery and the Slave Trade in the Sokoto Caliphate
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Last, Murray
- Published
- 2021
- Full Text
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182. The Psychoanalytic Study of Suicide, Part II: An Integration of Theory, Research, and Clinical Practice.
- Author
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Schechter, Mark, Goldblatt, Mark J., Ronningstam, Elsa, and Herbstman, Benjamin
- Subjects
PSYCHODYNAMIC psychotherapy ,IDENTITY (Psychology) ,SUICIDAL behavior ,DEVELOPMENTAL psychology ,BEHAVIOR therapy ,SUICIDE - Abstract
In Part I contemporary psychoanalytic concepts about suicide were synthesized with other theories and empirical research findings. Here the focus is on applying those principles and describing an integrative psychodynamic approach to treatment, one emphasizing the therapeutic alliance, unconscious and implicit processes, exploration of fantasy, and use of the therapeutic relationship as an implicitly interpretive vehicle for change. It is "integrative" because it draws on ideas and techniques described in dialectical behavioral therapy (DBT) and cognitive-behavioral therapy (CBT), as well on developmental and social psychology research. Psychotherapy with suicidal patients is inherently challenging, requiring the therapist to bear intense emotional pain while attending to potentially derailing countertransference pressures. The therapist plays an active role in helping the patient navigate affect storms and counter harsh self-attack, and instilling hope that treatment can lead to meaningful change. The integrative psychodynamic approach offers a pathway to a lessening of harsh self-judgment, greater connection with the body, improvement in continuity of experience, positive changes in narrative identity, emergence of the patient's genuine capacities, and more satisfying interpersonal relationships. These changes promote affect tolerance, improve life satisfaction, and decrease the likelihood of suicidal behavior. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
183. The Psychoanalytic Study of Suicide, Part I: An Integration of Contemporary Theory and Research.
- Author
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Schechter, Mark, Goldblatt, Mark J., Ronningstam, Elsa, and Herbstman, Benjamin
- Subjects
PSYCHODYNAMIC psychotherapy ,SUICIDE risk factors ,SUICIDE ,EMOTIONAL experience ,SUICIDE prevention ,SUICIDAL behavior ,SUICIDE victims - Abstract
Psychodynamic psychotherapy has an important role in suicide prevention. The psychoanalytic study of suicide has taught us a great deal about the human experience and the process of suicidality. There is also much to be learned from other fields of study and from empirical research that can be integrated into psychoanalytic therapies. Central to the psychoanalytic approach to suicide has been understanding the patient's internal subjective experience of unbearable emotional or psychic pain and the urgent need for relief. Emotional pain can include intense affects such as shame, humiliation, self-hate, and rage. Factors that can increase vulnerability to suicidal states include problems with early attunement, dissociation and deficits in bodily love and protection, conscious and unconscious fantasy, and certain character traits and dynamics. Empirical research has confirmed many basic psychoanalytic concepts about suicide, including escape from unbearable pain as the primary driver of suicidal behavior, the role of dissociation in increasing risk of bodily attack, and the importance of unconscious processes. Further research into implicit processes and their role in the suicidal process holds potential to improve suicide risk assessment and to enhance psychotherapy by bringing otherwise inaccessible material into the treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
184. UGO FOSCOLO IZMEĐU NEOKLASICIZMA I PREDROMATNIZMA.
- Author
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MEJDANIJA, Mirza
- Abstract
By the end of the 18th century, Italy was under Napoleon’s dominance. It was the time when centuries-long European values were being changed due to the Industrial, but also French revolution. The outcome of these enormous changes was an emergence of two artistic movements – neoclassicism and preromanticism that co-existed in Italy at the time. The most renowned Italian author of the 19th century, Ugo Foscolo, is a representative of both of these movements in the Italian literature. Neoclassicism and preromanticism emerged in the attempt to find an alternative to the same issues and, therefore, they co-existed in the same period of time, the elements of which are often present in the same authors, or even in one work of art. Foscolo is the author of Grazie, a neoclassical masterpiece of Italian literature, but also of the most significant work of the Italian preromanticism, the novel titled The Last Letters of Jacopo Ortis. Both of these works present an attempt to escape the disappointing circumstances of the period in question. What is relevant is not the different directions at which these attempts of escapism were pointed, but the very need to do so. Culturally, in both cases, the rejection of the reality is evident. Both tendencies may be observed as a quest for an alternative to the existing conditions that are depressing: for neoclassicism, the alternative is found in the ideal of beauty and harmony, distant from the historical horrors and defeats. For preromanticism, it is the depths of one’s own self, in the union with nature, pastorally viewed as the centre of life’s authenticity. The different directions of escapism are no longer of any importance, but the very need to escape, which is what these two movements have in common. What we are about to explore in the present paper are the characteristics of neoclassicism and preromanticism in Italian literature, primarily in the works of Ugo Foscolo, the most influential Italian author of that period. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
185. Springbok Escapers and Evaders in the Western Desert, 1941–1942: An Exploratory Investigation.
- Author
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Kleynhans, Evert and Gordon, Will
- Subjects
- *
PRISONERS of war , *WORLD War II , *DESERTS - Abstract
During the Second World War, between 1941 and 1942, a large number of South African troops were made prisoners of war (POW) by the Axis forces in the Western Desert. These troops were first interned in POW transit camps in North Africa, before being shipped to more permanent camps in Italy and later Germany. A large number of the South African captives decided to accept their newfound fates and make their internment as 'pleasant' as possible. However, a small nucleus of South African servicemen either tried to evade capture altogether, or, when captured, actively tried to escape. The first large scale attempts of escape and evasion by South African servicemen therefore occurred in North Africa between 1941 and 1942. This article provides an exploratory investigation into the varied experiences of the South African soldiers that either evaded capture altogether or escaped from internment in North Africa. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
186. Parę uwag wokół Ceny Anny Bikont.
- Author
-
Bieńczyk, Marek
- Abstract
Copyright of Holocaust: Studies & Materials is the property of Association Polish Center for Holocaust Research / Stowarzyszenie Centrum Badan nad Zaglada Zydow and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
187. Judith S. Kestenberg i ucieczka w (nie)pamięć o Zagładzie.
- Author
-
Naszkowska, Klara
- Abstract
Copyright of Holocaust: Studies & Materials is the property of Association Polish Center for Holocaust Research / Stowarzyszenie Centrum Badan nad Zaglada Zydow and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
188. Thermoregulation mode, substrate temperature and camouflage efficiency affecting defensive behavior of lizards in Amazonia
- Author
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Erika SOUZA, Ana COELHO, Alfredo P. SANTOS-JR, Ricardo Alexandre KAWASHITA-RIBEIRO, and Rafael de FRAGA
- Subjects
Cnemidophorus lemniscatus ,escape ,Gonatodes humeralis ,heliotherm ,non-heliotherm ,predation pressure ,Science (General) ,Q1-390 - Abstract
ABSTRACT In ectotherms, defensive responses to predators usually depend on cost-benefit relationships between death risk and the energy required to flee. In this study we investigate Amazonian lizards to test the hypothesis that the minimum predator approach distance (PAD) is influenced by temperature and camouflage. We test the hypothesis that PAD estimated for species with different thermoregulation modes respond differently to temperature and camouflage. We sampled 35 lizards of a heliotherm and a non-heliotherm species, for which we simulated a terrestrial visually oriented predator. Using a fixed-effects linear model, temperature positively affected PAD estimates, but the camouflage did not contribute to the model. Using a mixed linear model assuming thermoregulation mode as a random factor, camouflage negatively affected PAD estimates, independently of temperature. Our findings suggest that high exposure to predators in open habitats may be compensated by rapid fleeing optimized by high temperatures, and low fleeing performance, usually caused by relatively low temperatures in shaded habitats, may be compensated by camouflage. However, identifying the best PAD predictor greatly depended on accounting for thermoregulation mode in hypothesis testing, although the results obtained by both fixed and mixed-effects models may be relevant for conservation.
- Published
- 2020
- Full Text
- View/download PDF
189. Escape steering by cholecystokinin peptidergic signaling
- Author
-
Lili Chen, Yuting Liu, Pan Su, Wesley Hung, Haiwen Li, Ya Wang, Zhongpu Yue, Ming-Hai Ge, Zheng-Xing Wu, Yan Zhang, Peng Fei, Li-Ming Chen, Louis Tao, Heng Mao, Mei Zhen, and Shangbang Gao
- Subjects
escape ,neuromodulator ,cholecystokinin receptor ,NLP-18 ,CKR-1 ,neuropeptide ,Biology (General) ,QH301-705.5 - Abstract
Summary: Escape is an evolutionarily conserved and essential avoidance response. Considered to be innate, most studies on escape responses focused on hard-wired circuits. We report here that a neuropeptide NLP-18 and its cholecystokinin receptor CKR-1 enable the escape circuit to execute a full omega (Ω) turn. We demonstrate in vivo NLP-18 is mainly secreted by the gustatory sensory neuron (ASI) to activate CKR-1 in the head motor neuron (SMD) and the turn-initiating interneuron (AIB). Removal of NLP-18 or CKR-1 or specific knockdown of CKR-1 in SMD or AIB neurons leads to shallower turns, hence less robust escape steering. Consistently, elevation of head motor neuron (SMD)'s Ca2+ transients during escape steering is attenuated upon the removal of NLP-18 or CKR-1. In vitro, synthetic NLP-18 directly evokes CKR-1-dependent currents in oocytes and CKR-1-dependent Ca2+ transients in SMD. Thus, cholecystokinin peptidergic signaling modulates an escape circuit to generate robust escape steering.
- Published
- 2022
- Full Text
- View/download PDF
190. Reciprocally inhibitory circuits operating with distinct mechanisms are differently robust to perturbation and modulation
- Author
-
Ekaterina Morozova, Peter Newstein, and Eve Marder
- Subjects
half-center oscillator ,mutual inhibition ,dynamic clamp ,release ,escape ,temperature ,Medicine ,Science ,Biology (General) ,QH301-705.5 - Abstract
Reciprocal inhibition is a building block in many sensory and motor circuits. We studied the features that underly robustness in reciprocally inhibitory two neuron circuits. We used the dynamic clamp to create reciprocally inhibitory circuits from pharmacologically isolated neurons of the crab stomatogastric ganglion by injecting artificial graded synaptic (ISyn) and hyperpolarization-activated inward (IH) currents. There is a continuum of mechanisms in circuits that generate antiphase oscillations, with ‘release’ and ‘escape’ mechanisms at the extremes, and mixed mode oscillations between these extremes. In release, the active neuron primarily controls the off/on transitions. In escape, the inhibited neuron controls the transitions. We characterized the robustness of escape and release circuits to alterations in circuit parameters, temperature, and neuromodulation. We found that escape circuits rely on tight correlations between synaptic and H conductances to generate bursting but are resilient to temperature increase. Release circuits are robust to variations in synaptic and H conductances but fragile to temperature increase. The modulatory current (IMI) restores oscillations in release circuits but has little effect in escape circuits. Perturbations can alter the balance of escape and release mechanisms and can create mixed mode oscillations. We conclude that the same perturbation can have dramatically different effects depending on the circuits’ mechanism of operation that may not be observable from basal circuit activity.
- Published
- 2022
- Full Text
- View/download PDF
191. The adaptation of SARS-CoV-2 to humans
- Author
-
Eduardo Tosta
- Subjects
SAR-CoV-2 ,adaptive evolution ,mutation and variants ,escape ,immunity ,Microbiology ,QR1-502 ,Infectious and parasitic diseases ,RC109-216 - Abstract
The process of adaptation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans probably had started decades ago, when its ancestor diverged from the bat coronavirus. The adaptive process comprises strategies the virus uses to overcome the respiratory tract defense barriers and replicate and shed in the host cells. These strategies include the impairment of interferon production, hiding immunogenic motifs, avoiding viral RNA detection, manipulating cell autophagy, triggering host cell death, inducing lymphocyte exhaustion and depletion, and finally, mutation and escape from immunity. In addition, SARS-CoV-2 employs strategies to take advantage of host cell resources for its benefits, such as inhibiting the ubiquitin-proteasome system, hijacking mitochondria functions, and usage of enhancing antibodies. It may be anticipated that as the tradeoffs of adaptation progress, the virus destructive burden will gradually subside. Some evidence suggests that SARS-CoV-2 will become part of the human respiratory virome, as had occurred with other coronaviruses, and coevolve with its host.
- Published
- 2022
- Full Text
- View/download PDF
192. THE INDEX.
- Author
-
MUIR, DAVID
- Abstract
DAVID MUIR (ABC NEWS) (Off-camera) To "The Index." And quite an image tonight. Bulls escaping a rodeo in North Attleboro, Massachusetts. [ABSTRACT FROM PUBLISHER]
- Published
- 2024
193. SIRTÇANTALILARIN KAÇIŞ DENEYİMİ: AKIŞ KURAMI YAKLAŞIMI
- Author
-
Ceren İŞÇİ and Berrin GÜZEL
- Subjects
sırtçantalılar ,kaçış ,akış kuramı ,turistik deneyim ,backpackers ,escape ,flow theory ,touristic experience ,Social sciences (General) ,H1-99 - Abstract
ÖZ: Sırtçantalı hareket, turizm endüstrisi açısından önemli ve sürekli yükselen bir pazar olarak görülmektedir. Sırtçantalıların kitle turistinden farklı olarak, seyahatleri sırasında olağanüstü, yoğun bir deneyim olan akışı yaşadıkları, kendilerini mekânlara kaptırdıkları, zaman kavramını kaybettikleri, yüksek odaklanma, eğlence, merak hissi duydukları bilinmektedir. İlgili alan yazında, akış deneyiminin aynı zamanda önemli bir sırtçantalı motivasyonu olarak görülen kaçış deneyimine etkileri kuramsal olarak tartışılmış olsa da ölçülmemiştir. Mevcut çalışma, akış ve kaçış arasındaki bu ilişkiyi ölçmeyi amaçlamıştır. Araştırmada anket tekniğinden yararlanılmıştır. Anketler sırtçantalıların üye oldukları çeşitli çevrimiçi platformlardan toplanmıştır. Veri toplama süreci sonunda analiz edilebilir 231 anket formu elde edilmiştir. Akış ve kaçış deneyimlerini merkezine alan teori, yapısal eşitlik modeli ile test edilmiş, modelin iyi uyum endeksleri ürettiği ortaya çıkmıştır. Araştırma sonucunda eğlence/merak, odaklanılmış dikkat, zamanın kaybolması olmak üzere üç alt faktörden oluşan akışın, kaçış deneyimini pozitif yönde etkilediği saptanmıştır. ABSTRACT: Backpacking is an essential and rising market in the tourism industry. Other than mass tourists, it is known that backpackers have an extraordinary, intense experience during their vacations, immerse themselves to places/destinations, lose their sense of time, have a high concentration and sense of joy and curiosity. Although the effects of flow experience which is one of the primary motivations for backpackers on escape experience is discussed theoretically in the literature, it is not measured. The present study aims to measure the relationship between flow and escape experiences. Survey technique is used to gather data and the data is gathered from various online platforms which backpackers are members of. Among the obtained data, 231 questionnaires were analyzed. The theoretical model which focused on the flow and escape experiences is tested using structural equation modelling, and the model had good fitting indices. As a result of the study, flow which had enjoyment/curiosity, focused attention, distortion of time dimensions, affected the escape experience positively.
- Published
- 2019
- Full Text
- View/download PDF
194. Food capture and escape behavior of Leposternon microcephalum Wagler, 1824 (Squamata: Amphisbaenia)
- Author
-
H. Reiche, L. S. L. Hohl, and O. Rocha-Barbosa
- Subjects
feeding ,wormlizard ,behavior ,escape ,Science ,Biology (General) ,QH301-705.5 ,Zoology ,QL1-991 ,Botany ,QK1-989 - Abstract
Abstract Amphisbaenians are fossorial reptiles that have a cylindrical and elongated body covered with scales arranged in rings, and are all apodal, except for the three species of the genus Bipes. The amphisbaenian diet consists of a variety of invertebrates and small vertebrates. As these animals live underground, many aspects of their natural history are difficult to study. Most feeding studies of amphisbaenians have focused on the composition of the diet and feeding ecology, and the data available on feeding behavior are based on precursory observations. The present study describes the food capture behavior of Leposternon microcephalum Wagler, 1824 in captivity. In this experiment we used non-live bait (moist cat food), which was placed near a burrow opening, on the surface of the substrate. Three animals were monitored visually and filmed using cellphone cameras deployed at fixed points, to capture images from the dorsal and lateral perspectives of the study subjects. Two principal types of behavior were observed: the capture of food and defense mechanisms. The strategies used to capture the food were similar to those observed in other fossorial species. Although the backward movement has already been observed and described, we were able to record this movement being used as an escape strategy. These findings enrich our knowledge on different aspects of the natural history of the amphisbaenians.
- Published
- 2021
- Full Text
- View/download PDF
195. Academic Coping
- Author
-
Skinner, Ellen and Saxton, Emily
- Published
- 2020
- Full Text
- View/download PDF
196. Mechanism of sound production by the Chinese grasshopper Acrida cinerea (Orthoptera: Acrididae) during flight.
- Author
-
Kuga, Tatsuru and Kasuya, Eiiti
- Abstract
Many species of grasshoppers in subfamilies Oedipodinae, Gomphocerinae and Acridinae make sounds when they escape by flying. We carried out four kinds of experiments with the Chinese grasshopper, Acrida cinerea (Orthoptera: Acrididae: Acridinae), whose males often make sounds while flying, to examine the mechanism of sound production during flight by grasshoppers. First, we recorded high‐speed video and audio of the tethered flight of the males and found that they produced sounds when they clapped their hindwings together at the end of the upstroke. Second, we recorded the tethered flights of the males when we prevented them from clapping their hindwings to clarify whether the hindwing clapping produced the sounds, and we found that the obstruction of clapping hindwings prevented sound production by the males. Third, we recorded the free flight of the males and determined whether the sound produced by clapping hindwings was not specific to the tethered condition. The males clapped their hindwings during free flight, and sounds were produced when they clapped their hindwings. Finally, we observed the tethered and free flights of the females because the possibility of crepitation flight by the females existed, and we found that sound was produced by females clapping their hindwings during flight. These results showed that male A. cinerea make sounds during flight by clapping their hindwings, and females also have the ability to make sounds by using the same mechanism. This study provides the first experimental evidence on the mechanism of sound production during flight through observing the behaviors of grasshoppers. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
197. Interkulturelle Kompetenz in der Arbeit mit traumatisierten Menschen mit Fluchterfahrung.
- Author
-
Pichlhöfer, Christine
- Abstract
Copyright of Zeitschrift für Psychodrama und Soziometrie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
198. No hay dacalapata (carne), no hay reducción. La fuga de los indios de San Ignacio de los Tobas a comienzos del siglo XIX.
- Author
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Laura Cutrera, María
- Subjects
CREOLES ,NINETEENTH century ,FORTIFICATION ,RATIONING ,SCARCITY ,INDIGENOUS rights - Abstract
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- Published
- 2021
199. Analytic exploration of safe basins in a benchmark problem of forced escape.
- Author
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Karmi, Gleb, Kravetc, Pavel, and Gendelman, Oleg
- Abstract
The paper presents an analytical approach to predicting the safe basins (SBs) in a plane of initial conditions (ICs) for escape of classical particle from the potential well under harmonic forcing. The solution is based on the approximation of isolated resonance, which reduces the dynamics to a conservative flow on a two-dimensional resonance manifold (RM). Such a reduction allows easy distinction between escaping and non-escaping ICs. As a benchmark potential, we choose a common parabolic-quartic well with truncation at varying energy levels. The method allows accurate predictions of the SB boundaries for relatively low forcing amplitudes. The derived SBs demonstrate an unexpected set of properties, including decomposition into two disjoint zones in the IC plane for a certain range of parameters. The latter peculiarity stems from two qualitatively different escape mechanisms on the RM. For higher forcing values, the accuracy of the analytic predictions decreases to some extent due to the inaccuracies of the basic isolated resonance approximation, but mainly due to the erosion of the SB boundaries caused by the secondary resonances. Nevertheless, even in this case the analytic approximation can serve as a viable initial guess for subsequent numeric estimation of the SB boundaries. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
200. On the analysis of the fractal basins of escape in the N‐body ring problem.
- Author
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Navarro, Juan F. and Martínez‐Belda, M. C.
- Subjects
MANY-body problem ,NUMERICAL analysis ,CELESTIAL mechanics ,CHAOS theory ,MATHEMATICAL constants - Abstract
This article summarizes the results of a numerical investigation of the phenomenon of escape in the N‐body ring configuration, focusing on the scenarios that result for N = 5, 6, 7, 8 peripheral bodies. There is a critical value of the Jacobi constant of the system such that for smaller values, the potential well opens and test particles may leave the potential through any of its N openings. By means of a surface of section, we show the results of the computation of the basins of escape towards the different directions of escape, analyzing the structures that appear in them. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
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