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1. An experiment was carried out to examine if a heterogeneous diet consisting of pellets and coarse cereal particles would result in a similar feed intake to pelleted-only diets. It also considered whether coarser particles entering the gizzard would encourage the development of the gizzard and thus improve digestive tract functionality. Maize and wheat were hammer milled through a 3 mm screen after coarse grinding using either one of the two screens with a novel pattern. Three pellet-only diets were produced based on three grinding sizes. Additionally, four diets were produced by separating coarse cereal particles from moderately coarse particles by sieving either once or twice, pelleting the remainder and finally mixing these into a complete heterogeneous diet.2. No difference in performance between birds fed the three pelleted-only diets was observed. However, heterogeneous diets resulted in a lower feed intake (FI) and weight gain (WG) than pelleted-only diets (p < 0.05). The dietary treatments neither affected the feed conversion ratio nor ileal digestibility of starch and protein (p > 0.05). As expected, feeding a heterogeneous diets increased (p < 0.05) the relative weight of the gizzard and its contents. Approximately 50% of the particles in the small intestine were between 0.15 mm and 0.36 mm in diameter, with more fine particles observed when the pelleted-only diets containing coarsely ground cereals were fed, confirming the capacity of the gizzard to finely grind feed.3. Sieving of the diet remaining in the feeder during 4 h of feeding two of the heterogeneous diets showed that the particles > 2.8 mm disappeared first (p < 0.05), showing the birds’ preference for larger particles when offered heterogeneous diets. Although the birds were able to handle the coarse microstructure of the diets without any negative effects, the reduced performance in the case of heterogeneous diets might have been related to feed intake issues and particle selection, resulting in an imbalance in nutrient intake. [ABSTRACT FROM AUTHOR]

Background: This study aimed to assess the effects of enteral nutrition with different protein concentrations on muscle mass in severe pneumonia patients, providing insights for enteral nutrition practice in intensive care units (ICUs). Methods: A total of 120 severe pneumonia patients admitted to Dazhou Central Hospital's ICU between June 1, 2022, and February 1, 2023, meeting inclusion criteria, were randomly assigned to either a high-protein group (n = 60, 1.8 g/kg/d) or a standard-protein group (n = 60, 1.2 g/kg/d). Changes in relevant indicators were monitored on days 1, 5, and 10 of ICU admission, including quadriceps and diaphragm thickness, nutritional status (prealbumin and albumin), and adverse events such as diarrhea and constipation. Results: Autoregressive of order 1 model (AR(1)) analysis revealed a decrease in both quadriceps and diaphragm thickness over time in both groups. A significant group × time interaction was observed in quadriceps thickness. By day 10, compared to baseline, quadriceps thickness decreased in the high-protein (-0.315 cm [95% CI, -0.340 to -0.289]) and standard-protein (-0.429 cm [95% CI, -0.455 to -0.404]) groups. The high-protein group exhibited a lower quadriceps atrophy rate (13.97 ± 2.43%) compared to the standard-protein group (18.96 ± 2.61%), showing a significant difference (P < 0.001). No significant differences were found in diaphragmatic thickness between groups and over time. By day 10, both groups exhibited decreased diaphragmatic muscle thickness compared to baseline. The high-protein group (33.76 ± 5.09%) had a slightly lower phrenic atrophy rate compared to the standard-protein group (33.41 ± 4.53%). Both groups experienced enteral nutritional intolerance manifested as diarrhea, constipation, and other adverse events. Conclusion: High-protein enteral nutrition significantly improved quadriceps thickness and demonstrated good safety in severe pneumonia patients, suggesting its suitability for widespread clinical application. [ABSTRACT FROM AUTHOR]

Background: Psoriasis is a chronic inflammatory skin disorder associated with various comorbidities. The role of nutrition and dietary antioxidants in psoriasis management has gained attention. The Composite Dietary Antioxidant Index (CDAI) quantifies overall dietary antioxidant intake, but its association with psoriasis remains unclear. This study aimed to investigate the association between the CDAI and psoriasis, as well as the relationship between individual components of CDAI and psoriasis risk. Methods: Data from the US National Health and Nutrition Examination Survey (NHANES) were analyzed. Baseline characteristics, CDAI scores, and psoriasis status were assessed. Multivariable logistic regression and restricted cubic splines were employed to analyze the association. Results: The study included 23,311 participants, with 621 diagnosed with psoriasis. Higher CDAI scores were associated with a lower odds ratio (OR) of psoriasis occurrence (OR = 0.72, 95% CI 0.56–0.92, P = 0.009 in Model 3). Vitamin E intake exhibited an inverse correlation with psoriasis risk (OR = 0.76, 95% CI 0.60–0.96, P = 0.039 in Model 3). Other CDAI components did not show significant associations with psoriasis. Conclusion: This study demonstrates a significant inverse association between CDAI and psoriasis, indicating that higher dietary antioxidant intake is associated with a reduced risk of psoriasis. Specifically, higher vitamin E intake was associated with a lower likelihood of psoriasis. These findings underscore the potential role of dietary antioxidants in psoriasis management. Further research is warranted to elucidate the underlying mechanisms and explore targeted dietary interventions. [ABSTRACT FROM AUTHOR]

Background: The Infant and young child feeding (IYCF) practices directly affect the health, development and nutritional status of children under two years of age. However, IYCF counseling is one of the Community Health and Nutrition Volunteers (CHNVs) activities provided, which may contribute to improving the IYCF knowledge and practice among mothers. Since establishment of the CHNVs program in Yemen, its outcome has never been evaluated. Therefore, the aim of this study was to evaluate the role of CHNVs in improving the IYCF knowledge and practice among mothers in Hajjah governorate. Methods: A comparative cross-sectional study design was conducted in Bani Qais and Al-Maghrabah districts, Hajjah governorate between January and April 2023. A three-stage cluster sampling method was used to select districts, volunteer villages and households. A total of 926 mothers were interviewed. A pre-tested structured questionnaire was used to collect data. SPSS 26 was used for data analysis. The multinomial logistic regression and Chi-Square test were used to compare the IYCF knowledge and practices among mothers between the volunteer and non-volunteer villages. Odds Ratio (OR) with 95% Confidence Interval (CI) were calculated. A p-value < 0.05 was considered statistically significant. Results: The mothers in volunteer villages had significantly better breastfeeding and complementary feeding (CF) knowledge than mothers in non-volunteer villages. The OR of having good and moderate knowledge of breastfeeding were 3.5 (95%CI: 2.4–5.2) and 1.6 (95% CI: 1.2–2.2), respectively. The OR for good and moderate knowledge of CF were 1.7 (95% CI: 1.1–2.7) and 2.2 (95% CI: 1.5-3.0), respectively. Moreover, there is a statistically significant association in prevalence of Exclusively breastfed for the first two days after birth (EBF2D), Mixed milk feeding under six months (MixMF) and Bottle feeding 0–23 months (BoF) between volunteer and non-volunteer villages [(OR = 1.4, 95% CI: 1.0-1.8), (OR = 0.4, 95% CI: 0.2–0.8) and (OR = 0.5, 95% CI: 0.4–0.7), respectively]. Conclusions: The study found that CHNVs play a significant effect in improving the breastfeeding and CF knowledge, and prevalence of EBF2D, MixMF and BoF practices among mothers in their villages compared to non-volunteer villages. Future follow-up study and expansion to other settings in different governorates is recommended. [ABSTRACT FROM AUTHOR]

Introduction: To investigate the nutritional status of elderly Chinese patients with Parkinson's disease (PD) and analyze possible factors related to nutritional problems. Methods: Patients with PD aged 65 years or older were enrolled. Anthropometric assessment and Mini Nutritional Assessment were used to determine nutritional status. Various scales were completed to identify potentially related factors, such as Hoehn and Yahr stage (H&Y stage), 30 mL water swallow test, Clock Drawing Test (CDT), and Charlson Comorbidity Index (CCI). Results: 785 patients were enrolled. The prevalence of malnutrition and risk of malnutrition was 3.1% (24/785) and 25.7% (202/785), respectively. Regression analyses indicated that H&Y stage ≥ 3 (OR: 2.151; 95%CI: 1.174–3.941; p =.013), abnormal water swallow test (OR: 4.559; 95%CI: 2.130–9.759; p <.001), CDT score < 6 (OR: 2.810; 95%CI: 1.534–5.148; p =.001), and CCI (OR: 1.621; 95%CI: 1.238–2.124; p <.001) were considered to be potential factors associated with low BMI. Conclusion: 28.8% of elderly PD patients were in abnormal nutritional status. Disease severity, dysphagia, cognitive function, and comorbidities might be related factors. [ABSTRACT FROM AUTHOR]

AbstractThere are currently more than 3.3 million prostate cancer (PC) survivors in the United States. Conformance with national dietary guidelines and a good diet quality may lower the risk for Gleason grade progression in PC patients. Assessing the nutritional status of PC survivors is thus of paramount importance from a public health nutrition perspective. We used 24-h dietary recall data from the National Health and Nutrition Examination Surveys (NHANES) to systematically estimate nutrient intakes in n = 360 PC survivors (which may be extrapolated to represent n = 1,841,030 PC survivors) aged 70.69 years on average, and contrasted the results to the daily nutritional goals (DNG) in the 2020–2025 Dietary Guidelines for Americans (DGA). Diet quality in PC survivors was found to be generally poor, and the DNG as specified in the DGA were not met for many micronutrients, including calcium, magnesium and potassium. PC survivors had an insufficient intake of many vitamins (including vitamins A, C, D and E), and did not meet the intake recommendations for dietary fiber. Racial disparities in PC were reflected in the lower overall DQ in Non-Hispanic Black participants. Our results reiterate the need for nutritional assessment and counseling to improve DQ in PC patients. [ABSTRACT FROM AUTHOR]

AbstractObjectiveMethodsResultsConclusionThis study aimed to evaluate the efficacy of a double-lumen biliary-enteric tube (DBET) for enteral nutrition (EN) in individuals with malignant obstructive jaundice (MOJ).A retrospective cohort study was conducted using data from a prospectively maintained single-center database, including patients with MOJ. In the intervention group, DBET placement was performed concurrently with percutaneous transhepatic cholangiodrainage and biliary stenting, followed by postoperative EN (DBET-EN). In the control group, deep vein catheterization was undertaken after endoscopic biliary stenting, and parenteral nutrition (PN) was provided. A multivariable generalized linear model was used to assess the association between DBET-EN and 6-month mortality.A total of 74 patients were included in this study, comprising 28 patients in the intervention group (DBET-EN group) and 46 patients in the control group (PN group). Within the 6-month follow-up, 5 patients (17.9%) in the DBET-EN group and 20 (43.5%) in the PN group died. The multivariable generalized linear model demonstrated a significantly reduced 6-month mortality in the DBET-EN group compared to the PN group (adjusted odds ratio [OR]: 0.25, 95% CI: 0.08–0.81, P = 0.020). Secondary outcomes indicated that patients in the DBET-EN group had lower 9-month mortality rates and longer tube retention durations compared to the PN group (all adjusted P < 0.05). Postoperative liver function improved similarly in both groups. At 3, 6, and 9 months postoperatively, patient-generated subjective global assessment (PG-SGA) scores and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) scores were significantly higher in the DBET-EN group than in the PN group (P < 0.05).The implementation of DBET for EN in patients in the advanced stage of MOJ proved to be a minimally invasive and safe intervention. It significantly improved patients’ nutritional status and quality of life while reducing mortality. [ABSTRACT FROM AUTHOR]

Objective. The metabolic effects of metabolic syndrome (MetS) on musculoskeletal metabolism are controversial. This study explored the effect of MetS on bone mineral density (BMD) and muscle quality index (MQI). Methods. Data from the NHANES database from 2011 to 2014 were extracted, and nonpregnant participants aged 45–59 years were included. The included data were first weighted by complex sampling, and then, the effect of MetS on BMD and MQI was analyzed using multifactorial linear regression. We then performed a stratified analysis by gender and BMI classification. Moreover, a mediation analysis of MetS on BMD was conducted, with MQI as a mediating variable. A propensity score matching analysis method with a complex sampling design was additionally performed to verify the stability of the results. Results. A total of 1943 participants were eventually included. After adjusting for covariates, the results of linear regression show that MetS is associated with elevated pelvic BMD (beta = 0.03; 95% CI = 0.01, 0.06; P = 0.02) and reduced MQI, especially arm MQI (beta = −1.02; 95% CI = −1.27, −0.77; P < 0.0001). MetS is more associated with BMD in women, MQI in normal or heavyweight, and BMD in lightweight, according to stratified analysis. MQI explains the indirect effect of MetS on BMD (beta = 0.007; 95% CI = 0.003, 0.010). Conclusion. This study provides evidence that MetS elevates BMD and reduces MQI, and further, that there is a mediating effect of MQI on elevated BMD. [ABSTRACT FROM AUTHOR]

AbstractRadiotherapy is a common cancer treatment, and concurrent nutritional interventions can maintain nutritional status and improve clinical and supportive care outcomes. However, optimal nutritional interventions during radiotherapy are not firmly established. Herein, we assessed the feasibility, safety, and efficacy of dietary counseling interventions without oral nutrition supplements on health outcomes in adults receiving radiotherapy for cancer in a systematic review. Prospective clinical trials that implemented nutritional counseling interventions during radiotherapy were identified from four databases from inception through December 2023. Feasibility, safety, and efficacy were extracted from 32 articles that described 23 randomized and 4 non-randomized clinical trials. The interventions included individualized nutritional counseling (n = 14 articles), nutritional counseling plus exercise (n = 4), and nutritional counseling focused on increasing or reducing intake of specific nutrients (n = 9). Trials targeted head and neck (n = 12), pelvic cancers (n = 14), and/or breast (n = 5) cancers. Control groups had variable designs and included general nutrition education and intervention as needed. Studies recruited 120 ± 104 participants (range 26–468). Interventions tended to be feasible regarding retention and attendance at sessions, though feasibility metrics varied among different interventions. Most interventions were safe with no studies reporting adverse events attributable to dietary intervention. Individualized dietary counseling interventions tended to lead to between-group differences favoring the intervention group in regard to improved nutritional status, maintenance or attenuation of loss of body mass, improved quality of life, and reduced radiation-induced toxicities. Diets that encouraged/discouraged specific nutrients tended to recruit patients receiving radiation to the pelvic area and resulted in positive or neutral effects on gastrointestinal symptoms. In conclusion, nutritional interventions appear to be feasible, safe, and effective during radiotherapy for various symptom outcomes. [ABSTRACT FROM AUTHOR]

Aim Methods Results Conclusion This scoping review aims to assess the utility of ultrasound as a prospective tool in measuring body composition and nutritional status in the paediatric population. We provide a comprehensive summary of the existing literature, identify gaps, and propose future research directions.We conducted a systematic scoping review following the PRISMA Extension for Scoping Reviews guidelines. This involved screening titles and abstracts of relevant studies, followed by a detailed full‐text review and extraction of pertinent data.We identified and synthesised 34 articles. The review revealed that while ultrasound has been used to assess body composition and bone properties in children, significant gaps remain in the literature. These include limited studies on ultrasound performance, insufficient attention to relevant sample characteristics, reliance on manual image measurements, and limited sample diversity.Point‐of‐care ultrasound shows significant promise for assessing paediatric body composition and nutritional status. To validate and enhance its effectiveness, further research is needed. Future studies should include larger and more diverse patient cohorts and conduct longitudinal investigations to evaluate nutritional interventions. Additionally, developing artificial intelligence (AI) for standardising and automating data interpretation will be crucial in improving the accuracy and efficiency of ultrasound assessments. [ABSTRACT FROM AUTHOR]

Immunonutrition (IN) is defined as using special nutritional substrates (immnonutrients) to regulate the nutritional status as well as immune and inflammatory functions. Patients with cancer often have chronic inflammation and impaired immune function due to the disease and its treatment, affecting the quality of life of patients and the outcome of cancer treatment. Malnutrition, metabolic abnormalities, immune imbalances and inflammatory responses permeate the entire process of tumor development and progression. Therefore, IN has its great potential in the treatment of cancer patients. Although there has been a large body of evidence, the application of IN in cancer patients meets the challenge, such as the optimal administration time, application population, ingredients of IN, and the dosage and ratio of application etc. Besides, new studies with better designed are emerging. The aim of this review is to summarize recent evidences in IN in patients with cancer, and to guide the clinical application. [ABSTRACT FROM AUTHOR]

Objective: To explore the efficacy of different frequencies of Transcranial direct current stimulation (tDCS) treatment on swallowing disorders after stroke, to provide clinical guidance for the treatment of swallowing disorders after stroke. Methods: A total of 96 patients with swallowing disorders after stroke from January 2022 to June 2023 who were admitted in our hospital were selected, and divided into the low intensity group (n = 32) the moderate intensity group (n = 32), and the high intensity group (n = 32) by random number table method. The low intensity group was received 1.0 mA tDCS treatment, the moderate intensity group was received 1.5 mA tDCS treatment, and the high intensity group was received 2.0 mA tDCS treatment. The changes in wada drinking water test rating, swallowing ability and feeding ability, nutritional status, and quality of life in three groups were compared. Results: After treatment, the wada drinking water test rating in three groups were improved (P < 0.05) and compared with the low and moderate intensity group, the high intensity group was better (P < 0.05), while no significant difference in the low and moderate intensity group (P > 0.05) After treatment, the standardized swallowing assessment (SSA) scores in three groups were decreased (P < 0.05), the Functional Oral Intake Scale (FOIS) scores were increased (P < 0.05) in comparision of the low and moderate intensity group, the SSA score in the high intensity group was lower (P<0.05), and the FOIS score was higher (P < 0.05) while no significant difference in the low and moderate intensity group P > 0.05 ). After treatment, Hemoglobin (HGB), Parvalbumin (PA), Total protein (TP), and Transferrin (TFN) levels in three groups were increased (P < 0.05) in comparison of the low and moderate intensity group, the high intensity group was higher (P < 0.05), while no significant difference in the low and moderate intensity group (P > 0.05) After treatment, Activity of Daily Living Scale (ADL) and Swallowing Quality of Life (SWAL-QOL) scores in three groups were improved (P < 0.05) and compared with the low and moderate intensity group, the high intensity group was higher(P<0.05), while no significant difference in the low and medium intensity group (P > 0.05) Conclusion: High intensity tDCS has good therapeutic effect on swallowing disorders after stroke, which can promote improvement of swallowing function, enhance swallowing and feeding abilities, improve nutritional status, and improve quality of life [ABSTRACT FROM AUTHOR]

Background/Objectives: Geriatric hip fracture patients have an increased risk of malnutrition. Proper nutritional supply in the perioperative period is very important for their recovery. Oral nutritional supplements (ONSs) are recommended in geriatric hip fracture patients to improve dietary intake and prevent complications. This study aimed to evaluate the efficacy of postoperative ONSs after total hip arthroplasty in geriatric hip fracture patients. Methods: A retrospective study of elderly patients who underwent total hip arthroplasty for hip fracture was conducted. Data from patients who received ONSs postoperatively until hospital discharge (ONS group, n = 69) were compared with patients who did not receive ONSs (control group, n = 168). Laboratory test results, including serum protein and albumin levels, length of hospital stay, and the incidence of postoperative medical complications of the two groups, were analyzed. Results: Preoperative serum protein and albumin levels were significantly higher in the control group (p = 0.002 and p = 0.010, respectively). However, the degree of decline for both protein and albumin levels was significantly less in the ONS group (p < 0.001 for both). Serum albumin levels were significantly higher in the ONS group at postoperative two-week follow-up (p = 0.006). The length of hospital stay was shorter in the ONS group (p < 0.001). The incidence of postoperative delirium was significantly higher in the control group (p = 0.007). Conclusions: In geriatric hip fracture patients, postoperative ONSs can improve postoperative nutritional status, shorten the length of hospital stay, and reduce the incidence of postoperative delirium. [ABSTRACT FROM AUTHOR]

Background/Objectives: Protein–energy wasting (PEW) and sarcopenia are common in chronic hemodialysis (HD) patients, leading to numerous complications and increased mortality. This study aimed to compare the reliability of the SARC-F (Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls) and the Malnutrition–Inflammation Score (MIS) in assessing sarcopenia and predicting negative outcomes in HD patients. Methods: This cross-sectional study enrolled 109 HD patients. Nutritional assessments were performed, and blood samples were taken for routine blood laboratory investigations. The MIS was used as a scoring system to represent the severity of PEW, while the SARC-F was applied as an indicator of sarcopenia risk and general functional capacity. A multivariable logistic regression was conducted to analyze the association of several predictors with a negative cross-sectional outcome (death). Results: Patients with SARC-F scores ≥ 4 and MISs ≥ 6 were older, had significantly lower albumin and prealbumin levels, and more severe anemia. They were also more likely to report weight loss and poor appetite. A higher MIS was closely associated with unfavourable nutritional status according to the International Society of Renal Nutrition and Metabolism (ISRNM) criteria for PEW. However, in 71.25% of patients with satisfactory functional capacity (SARC-F scores 0–3), some form of PEW was still observed. After performing logistic regression modelling, only the MIS remained strongly associated with the probability of a negative outcome. Conclusions: The SARC-F alone often did not correspond to an increased sarcopenia risk or clear clinical and biochemical indicators of PEW in HD patients. When assessing nutritional risk in this group, it is recommended to use more detailed tools, such as the MIS, to ensure the accurate identification of those at the highest risk for negative outcomes. [ABSTRACT FROM AUTHOR]

It is known that female athletes are at risk for eating disorders. It is thought that factors such as pressure and stress experienced by professional athletes may affect emotional eating and body appreciation. In this context, the aim of this study was to evaluate the emotional eating and body appreciation of professional Turkish female athletes. A total of 265 professional female athletes were categorized according to their sport types and nationality. Emotional eating was found to be higher and body appreciation to be lower in athletes competing at the national level. The results of the hierarchical regression analysis, which included variables such as age, body mass index, professional sports background, national level, and sport type show that the most effective factor in explaining emotional eating in professional female athletes is body appreciation. The present study findings support that professional female athletes are at risk in terms of emotional eating and body appreciation. In addition, emotional eating scores were found to be higher and body appreciation scores were lower in national athletes. Psychological factors such as intense stress and pressure have an impact on the eating behavior and body appreciation of national athletes. These results suggest that athletes should be evaluated by nutritionists, doctors, and psychologists from a multidisciplinary perspective. [ABSTRACT FROM AUTHOR]

Boron- B is an essential element for the growth and development of plants. Its deficiency in hot, dry areas with calcareous soils can significantly reduce agricultural crop production. To study the impact of B fertilization, an experiment was conducted using a completely randomized design with seven treatments, including control, foliar spray (0.5, 1, and 2 g L−1 boric acid), and fertigation (0.5, 1, and 2 g L−1 boric acid). The experiment, with three replicates, was carried out in greenhouse conditions on pepper plants (Capsicum annuum cv. Lorca). The highest fruit yield was achieved with foliar spray at a concentration of 0.5 g L−1 and fertigation at 1 g L−1. Overall, the use of B fertilizer increased the concentration of macronutrients such as potassium-K (up to 27.79%), phosphorus-P (up to 59%), calcium-Ca (up to 49.61%), and magnesium-Mg (up to 158%), as well as micronutrients like iron-Fe (up to 59.55%), manganese-Mn (up to 29.03%), zinc-Zn (up to 81.81%), copper-Cu (up to 49.33%), B (up to 180%), and sodium-Na (up to 85.19%). It also decreased the concentration of nitrogen-N (up to 15%), sulfur-S (up to 21.36%), and chlorine-Cl (up to 48.02%) in the leaf tissue of pepper plants compared to the control treatment. These changes were influenced by the B concentration and type of fertilization. The results indicate that in calcareous soils with high pH, both fertigation and foliar spray methods can effectively address B deficiency in pepper plants by enhancing element absorption and increasing yield. [ABSTRACT FROM AUTHOR]

Introduction: Parkinson's disease (PD) is a highly prevalent disease characterized by motor and non-motor symptoms; the latter include constipation, which is considered a prodromal symptom. On the other hand, sarcopenia, polypharmacy, and malnutrition due to deficits are common in PD and lead to poorer health and quality of life. Objective: to associate constipation and use of levodopa with nutritional status, sarcopenia, duration and stage of the disease, and polypharmacy in individuals with PD. Materials and methods: analytical cross-sectional observational study where an online survey was applied to 161 people suffering from PD. Results: a significant association is observed between constipation and BMI (p = 0.022), as well as between the use of levodopa with BMI (p = 0.049) and polypharmacy (p = 0.046). On the other hand, there is a relationship between the average time of PD diagnosis and constipation (p = 0.0047). Finally, there is a relationship between SARC-F score applied to those over 60 years of age (p = 0.0446) and the use of levodopa. Having sarcopenia, being overweight, and having had the disease for less than five years is associated with a higher probability of experiencing constipation, according to the logistic regression analysis (p > 0.005). Conclusion: nutritional assessment and subsequent follow-up is of vital importance to avoid complications that could be associated with levodopa use, constipation, and sarcopenia. [ABSTRACT FROM AUTHOR]

Background: Obesity has increased cardiovascular morbidity and mortality. It is the leading risk factor for obstructive sleep apnoea (OSA). The relationship between obesity-OSA and vascular disease seems clear. There is no consensus on whether CPAP (continuous positive airway pressure) treatment prevents vascular events. Objective: The aim of this study was to determine the effect of comorbidity and obesity on the risk of vascular events in patients with OSA treated with CPAP. Method: This study was a prospective study of historical cohorts of adult patients with OSA and CPAP. The sample was 3017 patients. Descriptive, survival (Kaplan–Meier) and Cox regression analyses were performed, calculating crude and adjusted association relationships to explain the risk of vascular events. Results: A total of 1726 patients were obese, 782 were diabetics, and 1800 were hypertensive. The mean adherence was 6.2 (±1.8 h/day), and the mean follow-up time was 2603 days (±953.3). In the COX regression analysis, the event-related variables were baseline age (HR: 1.025: 1.012–1.037; p < 0.001), pre-treatment vascular event (HR; 2.530: 1.959–3.266; p < 0.001), hypertension (HR; 1.871: 1.187–2.672; p = 0.005) and abbreviated Charlson comorbidity index (HR; 1.289: 1.100–1.510; p = 0.002). Conclusions: The occurrence of vascular events in OSA patients on CPAP treatment is related to hypertension, having a vascular event before treatment, age at the start of CPAP use and abbreviated Charlson comorbidity index. [ABSTRACT FROM AUTHOR]

Featured Application: The proposed SMI-LE index can be used to plan healthier school lunches in line with the idea of a sustainable diet. The School Meal Index-Lunch Evaluation (SMI-LE) has been developed to assess school lunch quality. The aim of this study was to use the SMI-LE index for a comparative analysis of the quality of school meals planned in primary schools in Warsaw and Zagreb. The SMI-LE index was used to assess 4-week school meals in both cities. The collected menus were analyzed both in terms of overall quality as an average of points over 4 weeks and in terms of individual categories. According to the SMI-LE index, 4-week school lunches were rated on average 64 and 62 points out of a total of 140 points, in Warsaw and Zagreb, respectively. The majority of school lunches in Zagreb were classified as medium quality, while in Warsaw, over 50% were classified as good quality. Aspects that could be improved include an increase in vegetable availability and variety, limiting the meat dishes, and providing alternatives for children on vegetarian diets, as well as the ability to choose portion sizes. Polish schools need to change their approach to school meals. Following the example of schools in Zagreb, these could be one-course hot meals but with a wider range of raw vegetables and fruits. The current findings also highlight the importance of future research to develop standards for school food policies and investigate whether such a school food program could improve the eating habits and nutritional status of primary school children in the long term. Using the SMI-LE index to design new school meals could be a good solution to improve the quality of school meals. [ABSTRACT FROM AUTHOR]

Malnutrition is a multifactorial problem affecting older adults especially in developing countries like Nigeria. Eighty-five subjects which comprise 55 older adults and 30 controls were recruited. Total protein, Albumin, Calcium, Vitamin-C and Vitamin D were estimated using Biuret's method, Bromo-Cresol Green method, O-Cresolphthalein-Complexone, High performance liquid chromatography, and ELISA methods respectively. Cognitive and nutritional status information were obtained using Mini-Cog test and MNA-short form. Data were analyzed at p <.05. Activities of daily living (ADL) was observed to be associated with nutritional status in older adults. The prevalence of older adults at risk of malnutrition was found to be 58.2%. Blood pressure, albumin and total protein were significantly higher in older adults (p <.05) compared to the younger adults. Total protein was significantly higher in older female subjects (p <.05) compared to older male subjects. It was also significantly higher in non- institutionalized older adults than in those who were institutionalized. Calf circumference was significantly lower (p <.05) in those with poor cognitive status. BMI and calcium were significantly lower in the malnourished older adults. It is concluded that older adults who are dependent, most of which are institutionalized may be more exposed to malnutrition, frailty and cognitive impairment. [ABSTRACT FROM AUTHOR]

Nutritional status assessment, including amino acids, carnitine, and acylcarnitine profile, is an important component of diabetes care management, influencing growth and metabolic regulation. A designed case–control research included 100 Egyptian participants (50 T1DM and 50 healthy controls) aged 6 to 18 years old. The participants' nutritional status was assessed using the Body Mass Index (BMI) Z-score. Extended metabolic screening (EMS) was performed using a high-performance liquid chromatography-electrospray ionization-mass spectroscopy system to evaluate the levels of 14 amino acids, free carnitine, and 27 carnitine esters. T1DM children had considerably lower anthropometric Z-scores than the control group, with 16% undernutrition and 32% short stature. Total aromatic amino acids, phenylalanine, phenylalanine/tyrosine ratio, proline, arginine, leucine, isoleucine, free carnitine, and carnitine esters levels were considerably lower in the diabetic group, suggesting an altered amino acid and carnitine metabolism in type 1 diabetes. BMI Z-score showed a significant positive correlation with Leucine, Isoleucine, Phenylalanine, Citrulline, Tyrosine, Arginine, Proline, free carnitine, and some carnitine esters (Acetylcarnitine, Hydroxy-Isovalerylcarnitine, Hexanoylcarnitine, Methylglutarylcarnitine, Dodecanoylcarnitine, Tetradecanoylcarnitine, and Hexadecanoylcarnitine). HbA1c% had a significant negative correlation with Total aromatic amino acids, Branched-chain amino acid/Total aromatic amino acids ratio, Glutamic Acid, Citrulline, Tyrosine, Arginine, Proline, and certain carnitine esters (Propionylcarnitine, Methylglutarylcarnitine, Decanoylcarnitine, Octadecanoylcarnitine and Octadecenoylcarnitine), suggest that dysregulated amino acid and carnitine metabolism may be negatively affect the glycaemic control in children with TIDM. In conclusion, regular nutritional assessments including EMS of T1DM patients are critical in terms of diet quality and protein content for improved growth and glycemic management. [ABSTRACT FROM AUTHOR]

Objective:Design:Setting:Participants:Results:Conclusion:to investigate the predictors of vitamin D (vitD) status of undernourished and well-nourished children aged under five years in the North West Province of South Africa.this cross-sectional study assessed sociodemographic data, nutritional supplement intake, vitD-rich food consumption, and sunlight exposure via a structured questionnaire. Venous blood samples were collected to evaluate vitD, iron, and inflammatory markers.the maternal and child wellness departments of six community clinics in the JB Marks Municipality.121 undernourished and 51 well-nourished children, 6–59 months old.The prevalence of serum 25(OH)D < 30 ng/ml was 20.3%, 19.9%, and 21.6% in the total, undernourished, and well-nourished groups, respectively. The total mean 25(OH)D concentration was 38.41 ± 9.64 ng/ml. Age showed a negative association trend with 25(OH)D in the well-nourished group (β: −0.172, 95% CI −0.353, 0.010, p = 0.063), while household income was inversely associated with 25(OH)D (β = −1.86, 95%CI = −2.99, −0.733, p = 0.001) in the total group. Among the undernourished children, iron-deficiency anaemia (IDA) was associated with almost five times greater odds for 25(OH)D < 30 ng/ml (OR: 4.646, 95% CI 1.339, 16.123, p = 0.016). Intake of vitD supplements, therapeutic foods, multivitamins, and formula milk was associated with significantly higher 25(OH)D concentrations and was adjusted for in subsequent analyses. Additionally, consumption of eggs more than once a month was associated with higher 25(OH)D levels in the well-nourished children aged 24–59 months. Nutritional status, inflammation, and sunlight exposure were not associated with 25(OH)D concentrations.vitD insufficiency exists in both the undernourished and the well-nourished. Age, egg consumption, and IDA should be considered in the correction of vitD insufficiency in children.Trial registration: Pan African Clinical Trial Registry identifier: PACTR202110646172601.. [ABSTRACT FROM AUTHOR]

Introduction: This study aimed to evaluate the clinical impact of skeletal muscle mass and nutritional status in gastric cancer patients treated with nivolumab monotherapy as late-line treatment. Methods: We conducted a multi-institutional retrospective study of 90 gastric cancer patients who previously received anti-PD-1 therapy (nivolumab). On computed tomography images captured before nivolumab induction, the skeletal muscle index (SMI, cm2/m2) was defined as the erector muscle area (cm2) divided by the height (m) squared. Patients were divided into two groups: those with SMI-high (n = 45) and those with SMI-low (n = 45). Prognostic nutritional index (PNI) was also calculated before nivolumab induction. The associations of SMI and PNI with response rate (RR), progression-free survival (PFS), overall survival (OS), disease control rate (DCR), and safety were analyzed. Results: The cutoff values for SMI were determined as 13.45 for males and 10.41 for females. SMI-high was significantly associated with a higher RR (odds ratio = 12.36, p = 0.02) and DCR (odds ratio = 2.97, p = 0.02). Although not significant, PNI-high also tended to be associated with a higher RR. Multivariate analysis showed that SMI-high was independently associated with a higher RR and higher DCR in gastric cancer. Moreover, prognostic analyses revealed that SMI-high (log-rank test p = 0.008) and PNI-high (log-rank test p = 0.0008) were significantly associated with longer OS since nivolumab induction. SMI-high was also associated with longer PFS (log-rank test p = 0.03). There were no significant differences in immune-related adverse event between SMI-low and SMI-high. Conclusion: SMI and PNI were associated with nivolumab efficacy in gastric cancer patients. Management of skeletal muscle loss and nutritional status in gastric cancer patients who will receive nivolumab would be beneficial to enhance survival outcomes. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to evaluate the safety and efficacy of skull-femoral traction followed by osteotomy correction in patients with severe spinal scoliosis and split cord malformation. Methods: We retrospectively analyzed ten cases of severe spinal scoliosis with Pang I type split cord malformation treated between August 2012 and August 2023. Patients underwent skull-femoral traction prior to osteotomy correction. We assessed changes in height, weight, coronal and sagittal Cobb's angles, and physiological indicators such as vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and blood gas levels before, during, and after treatment. Results: Traction duration ranged from 9 to 19 days, with height and weight showing significant increases post-treatment. The coronal Cobb's angle improved from pre-treatment to post-corrective surgery and remained stable at the final follow-up. Similar improvements were observed in the sagittal plane. Physiological indicators such as VC, FVC, and FEV1, as well as blood gas levels, normalized after treatment. Nutritional status, indicated by triceps skinfold thickness, albumin, and transferrin concentrations, also improved. No neurological complications or device-related complications occurred during or after treatment. Conclusion: Skull-femoral traction followed by osteotomy correction is a safe and effective treatment for severe spinal scoliosis with split cord malformation, offering an alternative to high-risk procedures. [ABSTRACT FROM AUTHOR]

Assessing intraoperative hemodynamics with Surgical Apgar Score (SAS) and preoperative nutritional status with the Controlling Nutritional Status (CONUT) score are said to be useful to predict postoperative complications in many surgical services, but little is reported in the field of spinal surgery. The purpose of this study was to assess the utility of SAS and the CONUT score for predicting the risk of major postoperative complications after spinal surgery. We included 659 people who undergone spinal surgery in our institute in eight consecutive years. The occurrence of postoperative major complications was investigated. Background clinical information, surgical information including the SAS and the CONUT score, and the length of postoperative hospital stay were collected. The risk factors of postoperative complications were assessed statistically. Complications occurred in 117 cases (17.8%). The multivariate analysis showed that history of diabetes mellitus (odds ratio [OR] 1.81: P = 0.035), coronary disease (OR 3.33; P = 0.009), American Society of Anesthesiologists Physical Status (OR 1.71; P = 0.025), use of instruments (OR 2.07; P = 0.026), operation time (OR 1.30; P < 0.001), SAS (OR 0.59; P < 0.001), and CONUT (OR 1.34; P < 0.001) were independent risk factors of major complications after spinal surgery. Assessing the intraoperative hemodynamics with SAS and preoperative nutritional status with the CONUT score was useful in predicting major postoperative complications after spinal surgery. People who are detected as high risked people should be managed carefully after spinal surgery. [ABSTRACT FROM AUTHOR]

Background: With the advancement of world population aging, age-related sarcopenia (SP) imposes enormous clinical burden on hospital. Clinical research of SP in non-geriatric wards has not been appreciated, necessitating further investigation. However, observational studies are susceptible to confounders. Mendelian randomization (MR) can effectively mitigate bias to assess causality. Objective: To investigate the correlation between SP and comorbidities in orthopedic wards, and subsequently infer the causality, providing a theoretical basis for developing strategies in SP prevention and treatment. Methods: Logistic regression models were employed to assess the correlation between SP and comorbidities. The MR analysis was mainly conducted with inverse variance weighted, utilizing data extracted from the UK and FinnGen biobank (Round 9). Results: In the cross-sectional analysis, SP exhibited significant associations with malnutrition (P = 0.013) and some comorbidities, including osteoporosis (P = 0.014), body mass index (BMI) (P = 0.021), Charlson Comorbidity Index (CCI) (P = 0.006). The MR result also provided supporting evidence for the causality between SP and hypertension, osteoporosis and BMI. These results also withstood multiple sensitivity analyses assessing the validity of MR assumptions. Conclusion: The result indicated a significant association between SP and BMI, CCI, malnutrition, and osteoporosis. We highlighted that SP and comorbidities deserved more attention in non-geriatric wards, urging further comprehensive investigation. [ABSTRACT FROM AUTHOR]

Background: The benefits of exclusive breastfeeding (EBF) have been universally documented, with evidence of positive impacts on a child's optimal growth, development, and survival. However, EBF practices in Nepal have fluctuated and declined over the last 25 years. In addition to the individual factors of mothers and infants, EBF practices are affected by multiple community-level factors. Understanding these factors is essential for designing breastfeeding promotion programs to improve child nutritional status in Nepal. This study investigated the individual- and community-level determinants of EBF practices among young infants aged 0–5 months in Nepal. Method: We used the dataset from the Nepal Demographic and Health Survey 2022. Information on EBF in the past 24 h was available for 540 infants aged 0–5 months. A multilevel mixed-effect logistic regression was used to identify individual- and community-level factors associated with EBF among infants aged 0–5 months in Nepal. Results: The 24-hour prevalence of EBF among infants aged 0–5 months was 57.46% (95% confidence interval (CI): 52.18, 62.57). The infant's age was inversely associated with EBF prevalence at the individual level. Compared with infants aged < 1 month, infants aged three months (adjusted odds ratio (AOR): 0.14, 95% CI: 0.05, 0.40), four months (AOR: 0.11, 95% CI: 0.04, 0.28), and five months (AOR: 0.07, 95% CI: 0.03, 0.20) were less likely to receive EBF. At the community level, community-level variables such as ≥ 4 ANC visits coverage, maternal employment status, and poverty level were generated by aggregating the individual characteristics in a cluster and were categorized using quartiles into low ("< 25%"), moderate (25–75%), and high (≥ 75%). Mothers from communities with moderate ≥ 4 ANC visits (AOR: 3.30, 95% CI: 1.65, 6.57) and high ≥ 4 ANC visits (AOR: 2.70, 95% CI: 1.40, 5.22) coverage had higher odds of EBF practices than did those from communities with low ≥ 4 ANC visits coverage. Similarly, communities with moderate (AOR: 2.67, 95% CI: 1.34, 5.30) and high (AOR: 2.34, 95% CI: 1.10, 4.99) levels of maternal employment status and moderate levels of poverty (AOR: 2.20, 95% CI: 1.13, 4.28) were associated with a higher likelihood of EBF practices. Subnational level variation was evident, with infants in Lumbini province having lower odds of EBF (AOR: 0.32, 95% CI: 0.13, 0.77) relative to Koshi province. Approximately 9% of the variation in EBF practices was observed among mothers while mapping across clusters in this study. Conclusion: Various individual- and community-level factors influence the uptake of EBF in Nepal, underscoring the need to improve the approaches and strategies of EBF programs. This study highlighted the significant association of community-level factors (≥ 4 ANC visits coverage, poverty level, and maternal employment status) with EBF among infants under 6 months. It revealed approximately 9% variability in EBF across clusters. Future efforts to promote EBF should focus on older infants and communities with low poverty levels and low coverage of recommended ≥ 4 ANC visits. Furthermore, context-specific adaptation of such efforts might be required considering the variation observed between the communities in the present study. [ABSTRACT FROM AUTHOR]

Background: To reduce neonatal mortality, it is necessary to identify neonates with fetal malnutrition at birth using the clinical assessment score (CAN score). Furthermore, comprehensive summary data that shows burden of fetal malnutrition in Africa is scarce. As a result, this systematic review and meta-analysis aimed to assess fetal malnutrition among newborns in Africa. Method: The PRISMA guidelines were used for this study. Articles were obtained from databases and websites. The outcome of the study was fetal malnutrition, as determined using the CAN score. The meta-analysis of the primary and secondary outcomes was performed using Stata version 18 statistical software. The pooled prevalence with a 95% CI was estimated using the random effect method with the Der Simonian Liard model. Results: This meta-analysis and systematic review included 5356 newborns from 13 studies. The pooled prevalence of fetal malnutrition (FM) among newborns diagnosed using the CAN score in Africa was 19% [95% CI: 17, 22]. Based on subgroup analysis by publication year, the lowest prevalence of fetal malnutrition 17% (95% CI: 9–27) was observed in the studies published in the years 2020–2023. Maternal and fetal factors were significantly associated with fetal malnutrition. Conclusion: Nearly one-fifth of neonates delivered in Africa were found to have fetal malnutrition based on the clinical evaluation of nutritional status. It has also been established that maternal malnutrition, a lack of proper treatment during pregnancy, maternal malnutrition, and newborn morbidities were associated with fetal malnutrition. To prevent fetal malnutrition, integrated efforts should be made for early maternal infection screening. Furthermore, maternal nutritional therapy should be explored for malnourished pregnant women. [ABSTRACT FROM AUTHOR]

Introduction. The pattern of diet intake is associated with food availability and the intake of nutrients from different food groups and is an important component of nutritional status. The dietary habits of individuals are integral to understanding their nutritional wellbeing, making this assessment crucial for public health interventions. The objective of the study was to assess the dietary intake pattern and nutritional status among women of reproductive age in slum areas of Pokhara Metropolitan. Methodology. A cross‐sectional analytical study was conducted to assess the dietary intake pattern and nutritional status among 404 women of reproductive age in the slum area of Pokhara from June 2019 to December 2019. A simple random sampling technique was used to select the wards while a purposive sampling technique was used to collect the samples. 24‐hour recall meal‐based questions and anthropometric measurements were used for collecting data. Data were entered into EpiData and analyzed using SPSS version 16 software for analysis. Frequency and mean, median, chi‐square test, and logistic regression were performed. Results. The mean (±SD) age (SD) of the participants was 31 (±9.25) years, and most of the participants belonged to the age group 25–35 years. Out of 404 women of reproductive age, 99% of the participants consumed starchy staple foods daily, while 56.7% ate vegetables daily, and nearly half frequently consumed prepackaged foods and soft drinks. Among the total participants, 41.3% were found with a normal BMI, 37.6% were overweight, and only 12.4% were underweight. There was a significant association between underweight and age, women's occupation, and frequency of food consumption per day. Age, knowledge of nutrition, and frequency of food consumption per day were found to be associated factors with being overweight at a p value <0.05. Conclusion. Age, occupation status, and frequency of food consumption were the key predictors of being underweight, and age, knowledge regarding nutrition, and frequency of meals were the key predictors of being overweight. Developing countries must emphasize the importance of considering these factors in public health interventions and strategies aimed at promoting healthy weight management. More studies are needed. [ABSTRACT FROM AUTHOR]

Background Method Results Conclusions People diagnosed with Inflammatory bowel disease (IBD) often have severe dietary restrictions and avoidance due to the uncertainty of intestinal symptoms. Inadequate dietary intake may increase the risk of malnutrition and result in impaired food‐related quality of life (FRQoL). Few studies investigated factors influencing FRQoL in patients with IBD. This study aimed to synthesize the existing evidence regarding FRQoL among patients with IBD, including the current situation, measurement instruments, and related influencing factors.The comprehensive literature search was conducted in databases including PubMed, Embase, CINAHL, PsycInfo, Cochrane Library, as well as the most commonly used Chinese databases (CNKI, Wanfang and CBM). Studies published between January 2015 and December 2023 on FRQoL in patients with IBD were included. The Joanna Briggs Institute (JBI) critical appraisal checklist was utilized to evaluate the methodological quality of the selected studies.Finally, only five studies met the inclusion criteria were reviewed, including three cross‐sectional studies and two case‐control studies. The Food‐related quality of life‐29 Scale (FR‐QoL‐29) with a total core of 145 was the most used instrument measuring FRQoL in patients with IBD. The mean scores of FRQoL ranged from 69.9 to 102.3 in adult patients with IBD and 94.3 in children. A diverse range of factors were associated with FRQoL, including socio‐demographic, clinical, psychological, diet‐related, and nutrient intake factors.The main influencing factors of FRQoL among patients with IBD included disease activity status, severe symptoms, history of IBD surgery, negative emotion reaction, and restrictive eating behaviour. Clinicians should work in concert with dietitians, keeping an eye on the disease status, nutrition intake, and restrictive eating habits, assessing FRQoL and providing personalized dietary recommendation for the patients with IBD. [ABSTRACT FROM AUTHOR]

Background: Malnutrition and sarcopenia significantly increase the risk of intra-hospital delirium, particularly among older adults. Given the potential correlation between calf circumference (CC) and these conditions, CC emerges as a promising predisposing factor for delirium. This study aims to investigate the independent association between delirium and anthropometric parameters, focusing on evaluating CC's predictive capacity for intra-hospital delirium risk. Additionally, it aims to compare CC's predictive performance with the widely used Mini Nutritional Assessment (MNA), while also considering potential gender disparities. Methods: This is a retrospective study which enrolled patients aged ≥ 65 years from September 2021 to March 2022 at the Padova Hospital (Italy). Physical characteristics, intra-hospital delirium incidence, and body composition were assessed. Sarcopenia was diagnosed using the 2019 European Consensus criteria. Results: Among 207 subjects, delirium affected 19% of patients. CC showed a significant association with intra-hospital delirium among the analyzed anthropometric parameters. ROC curves indicated that CC's predictive capacity for delirium onset was comparable to MNA (p = 0.98), particularly in women. In a multivariable logistic regression model, female gender and higher cognitive and CC scores emerged as protective factors against delirium onset, with each unit increase in CC associated with a 24% reduction in the odds of delirium. Conversely, sarcopenia did not significantly influence delirium onset. Conclusions: CC shows promise as a predisposing factor for intra-hospital delirium, similar to MNA, albeit with significant gender differences. CC could serve as a valuable tool for assessing delirium risk among female patients. Further validation of these findings is necessary through larger-scale studies. [ABSTRACT FROM AUTHOR]

Background: Malnutrition is common in older patients with chronic heart failure (HF) and often accompanies a deterioration of their condition. The Controlling Nutritional Status (CONUT) score is used as an objective indicator to evaluate nutritional status, but relevant research in this area is limited. This study aimed to report the prevalence, clinical correlates, and outcomes of malnutrition in elder patients hospitalized with chronic HF. Methods: A retrospective analysis was conducted on 165 eligible patients admitted to the Department of Cardiology at Huadong Hospital from January 2021 to December 2022. Patients were categorized based on their CONUT score into three groups: normal nutrition status, mild risk of malnutrition, and moderate to severe risk of malnutrition. The study examined the nutritional status of this population and its relationship with clinical outcomes. Results: Findings revealed that malnutrition affected 82% of the older patients, with 28% experiencing moderate to severe risk. Poor nutritional scores were significantly associated with prolonged hospital stay, increased in-hospital mortality and all-cause mortality during readmissions within one year (P < 0.05). The multivariable analysis indicated that moderate to severe malnutrition (CONUT score of 5–12) was significantly associated with a heightened risk of prolonged hospitalization (aOR: 9.17, 95%CI: 2.02–41.7). Conclusions: Malnutrition, as determined by the CONUT score, is a common issue among HF patients. Utilizing the CONUT score upon admission can effectively predict the potential for prolonged hospital stays. [ABSTRACT FROM AUTHOR]

AbstractThe production of Moringa oleifera L. using sustainable and accessible regional inputs constitutes an alternative to boost its cultivation in tropical environments. This study aimed to evaluate the production of M. oleifera seedlings cultivated in substrate constituted of different proportions of organic compost and soils. The treatments consisted of substrates obtained from five proportions of organic compost from tree pruning and bovine manure (0:100; 20:80; 40:60; 60:40, and 80:20 v/v of organic compost and soil). After 120 days of sowing, the following evaluations were carried out: root length, plant height, stem diameter, aerial part dry matter mass, roots, total and their relationships, chlorophyll A, B and total, Dickson Quality Score and accumulations of nitrogen, phosphorus and potassium in the aerial part dry matter mass. The application of different proportions of organic compost for the formulation of the substrate stimulated the growth of M. oleifera seedlings for all the variables analyzed. The dose of organic compost that provided greater responses based on Dickson Quality Index was 73% of organic compost added to the soil to form the substrate and therefore recommended for the production of M. oleifera L. [ABSTRACT FROM AUTHOR]

AbstractImportanceObjectiveResultsConclusion\nKEY POINTSMany individuals with irritable bowel syndrome (IBS) have insufficient or deficient serum 25-hydroxyvitamin D [25(OH)D] status; however, it is not clear if improved vitamin D nutritional status through higher intake can improve symptom severity and quality of life.This systematic review and meta-analysis aimed to identify if changes in vitamin D intake or status affect symptom severity and quality of life in adults with IBS.Data Sources: MEDLINE®, Cochrane Central Register of Controlled Trials, Global Health, EMBASE, and Web-of-Science databases were systematically searched for relevant articles to August 12, 2024, in the English language.Study Selection: Clinical trials, prospective observational studies, and Mendelian randomization (MR) analyses reporting the effect of vitamin D intake or status on IBS-related outcomes were included.Data Extraction and Synthesis: Article review and data extraction were conducted by 2 authors following the PRISMA guidelines. Random effects meta-analyses and the Nutrition Quality Evaluation Strengthening Tools to assess risk of bias were employed for randomized controlled trials.Main Outcome(s) and Measure(s): Primary outcomes included measures of serum 25(OH)D status, symptom severity, and quality of life.12 studies from 15 articles were included (n = 7 RCTs; n = 3 single-arm interventions; n = 2 MR). Seven study populations had deficient (<20 ng/mL) and three had insufficient (21–29 ng/mL) baseline serum 25(OH)D status. RCTs measured changes in serum 25(OH)D after 6–26 wks with 3,000 IU daily to 50,000 IU bi-weekly vitamin D dosages. Meta-analyses of low risk-of-bias RCTs revealed increased 25(OH)D levels in groups treated with oral vitamin D compared to placebo (n = 5; Pooled mean difference [95% CI]: 20.33 [12.91, 27.74] ng/mL; I2 = 97.9%). Quality of life scores improved significantly in deficient populations (n = 3; 3.19 [2.14, 4.24]; I2 = 0.0%). Non-significant decreased trends in IBS symptom severity were shown across populations (n = 6: −25.89 [-55.26, 3.48]; I2 = 92.8%).Moderate level evidence indicate vitamin D supplementation may improve status in adults with IBS and quality of life in those with deficient status at baseline.Question: Do changes in vitamin D intake or status affect symptom severity and quality of life in adults with irritable bowel syndrome?FindingsIn this systematic review and meta-analysis, moderate level evidence supports vitamin D supplementation for improving serum 25-hydroxyvitamin D status in adults with IBS and for increasing quality of life scores in those with deficient status at baseline.Meaning: Vitamin D supplementation may improve quality of life in IBS patients with deficient serum 25-hydroxyvitamin D status. [ABSTRACT FROM AUTHOR]

Summary Objective Methods Results Conclusion Assess longer‐term changes in food habits and anthropometry among Grades 1–2 primary school students from four public schools in Colombo, Sri Lanka, following a 3‐week programme including a classroom‐based motivational storybook discussion and self‐monitoring food diary (FD).This follow‐up study assessed changes from baseline (pre‐intervention) BMI z‐scores and food habits (increased healthy food‐item consumption/decreased unhealthy food‐item consumption reflected by an increase in FD score) and parental perceptions (anonymous questionnaires) among 863 students (aged 6–8 years), between 9 and 12 months after completing the programme (November 2019–February 2020).Food habits showed sustained improvement from baseline mean FD score (baseline vs. follow‐up: 51 ± 23% vs. 67 ± 22%, p < 0.001), with children from all BMI subgroups (underweight [UW], normal weight [NW], overweight [OW] and obesity [OB]) showing a significant increase in FD scores (ranging from 14.1% to 17.2%, p < 0.001). BMI z‐scores increased in children living with UW (−2.85 to −2.21, p < 0.00) and NW (−0.70 to −0.57, p < 0.001), but did not change in children with OW (+1.5 to +1.49, p = 0.83) and OB (+2.85 to +2.21, p = 0.19). Most parents (n = 497, 97.8%) reported satisfaction with programme outcomes.This programme led to sustained improvement in food habits among young primary school children from all BMI categories, increase in BMI towards the median among children living with UW and NW, and stabilization of BMI in children with OW and OB, suggesting it as a useful tool for improving nutritional status of young children in low‐ and middle‐income countries (LMIC) facing the double burden of under‐ and overnutrition. [ABSTRACT FROM AUTHOR]

Background: Little is known on the prospective associations between an empirically derived dietary pattern (DP) and life satisfaction among adolescents. This PUTRA-Adol follow-up study aimed to assess the prospective associations between the empirically derived DP and life satisfaction during adolescence. Methods: A total of 585 and 262 adolescents participated in the baseline PUTRA-Adol study in 2016 and PUTRA-Adol follow-up study in 2019–2020, respectively. These adolescents were recruited from three southern states in peninsular Malaysia, namely Negeri Sembilan, Melaka and Johor. Dietary assessments were estimated using a validated food frequency questionnaire (FFQ) while a Multidimensional Students' Life Satisfaction Scale (MSLSS) was used to measure life satisfaction at baseline in 2016 as well as at follow-up in 2019–2020. A DP characterised by foods high in free sugar and energy dense was identified using reduced rank regression (RRR), cross-sectionally at baseline and was reported elsewhere. Similar RRR analysis was used to find a DP that best explained the variation in response variables linked to poorer life satisfaction, including dietary energy density (DED), fiber density, and percentage of energy from total fat and sugar at the PUTRA-Adol follow-up study. Prospective relationship between adherence to the identified DPs and overall life satisfaction scores as well as its domains between 2016 and 2019–2020 were evaluated using generalized estimating equation models (GEE). Results: A DP characterized by high intakes of percentage energy from sugar, fibre and low in DED and percentage energy from total fat was identified at the 2019–2020 follow-up. The identified DP explained 11% of total variations in the response variables and was characterized by high intakes of sweets, sugar sweetened beverages (SSB) and fruits. Female adolescents [67.6(8.9)] had a mean (SD) of life satisfaction that was higher than male adolescents [67.5(10.8)] p < 0.05 in 2019–2020. Prospective analysis found a significant positive association between the identified DP and school domain, in male adolescents (β = 0.117; 95% CI 0.001, 0.234) and an inverse relationship between the DP z-score and self-domain in all adolescents (β = − 0.060; 95% CI − 0.115, − 0.005) from 2016 to 2019–2020. Conclusions: An increasing score for the predominant 'High sugar and High fibre' DP was prospectively associated with increasing life satisfaction score for the school domain in male adolescents and decreasing score for self-domain in both male and females during adolescence. A lifestyle intervention targeting reduced dietary intakes, particularly sugar, may improve life satisfaction in adolescents and promote healthier future without compromising dietary intakes for chronic disease prevention later in life. [ABSTRACT FROM AUTHOR]

Normal respiratory rates (RR) for children under five in the tropics are well-documented, but data for older children are limited. This study tracked RR changes with age and examined associations with nutritional status and environmental factors. We monitored rural Gambian children aged 6 months to 14 years, recording RR during home visits twice weekly over two rainy seasons. Using a generalized additive model, we constructed RR reference curves, and a linear mixed-effect model identified factors influencing RR. A total of 830 children provided 67,512 RR measurements. Their median age was 6.07 years (interquartile range 4.21–8.55) and 400 (48.2%) were female. Age, stunting, ambient temperature, and time of RR measurement were independent predictors of respiratory rate. Strikingly, children showing signs of illness had greater variability in repeat RR measurements. We constructed a RR reference chart for children aged one to 13 years and proposed a cutoff of > 26 breaths/min for raised RR among children aged > 5 years bridging an important gap in this age group. Although the time of data collection, nutritional status, and ambient temperature were predictors of RR, their effect size is not clinically significant enough to warrant a change in the current WHO guidelines owing to the prevailing uncertainty in the measurement of RR. The finding that RRs between repeat measurements were more variable among children with signs of illness suggests that a single RR measurement may be inadequate to reliably assess the status of sick children—a population in which accurate diagnosis is essential to enable targeted interventions with lifesaving treatment. [ABSTRACT FROM AUTHOR]

Background Aims Methods Results Conclusions Science‐based decisions regarding forest management require the knowledge of the impact of thinning regimens on the forests’ vitality and resilience. There is no systematic study analysing the role of forest management approaches on the nutritional status of forests, serving as a surrogate for their health and growth.We assessed the impact of ‘heavy thinning from above’ versus ‘no management’ on the foliar chemistry of old‐growth European beech stands on a calcareous site with cambisol/chromic luvisol soil in Thuringia, Germany.Macro‐ and micronutrients were analysed by serial foliar analysis of six trees per experimental plot over 13 years (2009–2021). To assess potential differences of foliar chemistry between the two plots and over time, a linear mixed‐effects model was applied.Foliar concentrations of all macro‐ and micronutrients were not significantly different between the two plots (p > 0.05), demonstrating that the management approach had no relevant impact on the nutritional status of beech trees growing at the calcareous site. Furthermore, all foliar concentrations were dynamic over the 13‐year evaluation period. Hence, long‐term forest monitoring is crucial to capture the complex interplay between the trees and environmental conditions.Serial foliar analysis allows for a reliable evaluation of a forest's nutritional status. The results indicate that either regimen, that is, ‘heavy thinning from above’ or ‘no management’, shall not pose any risk in terms of growth and stability. Our results add to the understanding of beech forest dynamics and may provide a further piece for science‐based strategies of sustainable forest management. [ABSTRACT FROM AUTHOR]

Background: Malnutrition in the elderly places a significant burden on healthcare, social, and aged-care systems, yet it often remains undiagnosed and untreated. This study aims to evaluate family physicians' knowledge and attitudes towards the diagnosis and treatment of malnutrition in the elderly. Methods: Based on a literature review, an online questionnaire was developed, comprised of seven knowledge-related items and eight attitude-related questions regarding malnutrition in elderly populations. We also assessed the feasibility of including two malnutrition screening questions in regular clinic visits for individuals aged ≥ 70 years. Results: Surveys were completed by 126 physicians (35% response rate), mean age 47.2 ± 12.6 years; 15.6 ± 12.5 years of practice; 67% females; and 92% board-certified family physicians. Moreover, 77.6% agreed that diagnosing malnutrition is important in patients with decreased appetite. Most respondents demonstrated knowledge of nutritional screening principles (63.5%) and recognized that even obese elderly individuals could be malnourished (83.2%). There was partial agreement (60%) that normal BMI values in the elderly differ from those in younger populations. Almost complete agreement was seen for incorporating two nutritional status questions in medical visits (91%), with physicians expressing willingness to receive training in malnutrition identification and screening tools. Despite challenges such as time constraints and limited knowledge, participants were open to conducting biannual malnutrition risk screening for elderly patients. Conclusion: We recommend malnutrition screening in primary care followed by malnutrition diagnosis and referral of malnourished patients to the proper intervention. [ABSTRACT FROM AUTHOR]

Background: This study aims to investigate the association between malnutrition and early childhood caries (ECC) and caries activity among children aged 3–5 years, in order to provide a theoretical basis for preventing and blocking ECC and improving malnutrition. Methods: Children aged 3–5 years from six kindergartens in Zhao Xian, China were enrolled in this study. The decayed, missing, filled teeth (dmft) of all children were examined and recorded. The Cariostat method was used to detect dental caries activity, collect anthropometric data and measure haemoglobin concentration. Parents were asked to complete a questionnaire on the general characteristics and oral health behaviour of the participants. The "Growth Standards for Chinese Children Under 7 Years Old" was used to assess the nutritional status of all participating children. Wilcoxon rank sum test and multivariate logistic regression analysis were used to analyse and evaluate the relationship between ECC, caries activity and malnutrition. Results: A total of 635 children who met the criteria were included in this study. After adjusting for confounding factors, logistic regression showed that the risk of ECC was significantly increased in underweight children compared with normal children (OR = 5.43, P < 0. 05); compared with normal children, the risk of ECC decreased in overweight and obese children (OR = 0.31, P < 0.001); underweight children had higher caries severity than normal weight children, and the difference was statistically significant (OR = 2.69, P < 0. 05); stunted children had higher caries severity than normal weight children and the difference was statistically significant (OR = 2.28, P < 0.05); underweight was positively associated with caries activity and the association was statistically significant (OR = 2.33, P < 0. 05); stunting was positively associated with caries activity and the association was statistically significant (OR = 2.1, P < 0.05); overweight and obesity were negatively associated with caries activity and the association was statistically significant (OR = 0.61, P < 0.05). Conclusions: The risk of ECC among children aged 3–5 years was positively associated with undernutrition and negatively associated with overnutrition. The severity of ECC among children aged 3–5 years was positively associated with undernutrition. The caries activity among children aged 3–5 years was positively associated with undernutrition and negatively associated with overnutrition. [ABSTRACT FROM AUTHOR]

Background: Neurological diseases resulting from nervous system injuries can significantly impact nutritional status and the physical and cognitive capacities necessary for maintaining a sufficient diet. This study focuses on primary nutritional therapies for neurological illnesses. Methods: An integrative literature review was conducted using three databases: PePSIC, Medline, and LILACS. A comprehensive search strategy was employed, incorporating descriptors such as neuropathies, nutritional therapy, efficacy, and side effects. Results: After applying inclusion criteria, 175 relevant items were identified. While traditional medical interventions for neurological conditions typically involve medication, food therapy has shown promise in enhancing clinical outcomes and alleviating symptoms for certain diseases. Specifically, food therapy has been effective in improving the prognosis of adrenoleukodystrophy and mitigating symptoms of Wernicke-Korsakoff syndrome and epilepsy. Conclusion: Patients with neurological illnesses, such as adrenoleukodystrophy, Wernicke-Korsakoff syndrome, and epilepsy, may benefit from dietary interventions to improve prognosis and alleviate symptoms. Therefore, healthcare professionals should consider incorporating food therapy into the treatment plans for these conditions to optimize patient outcomes. [ABSTRACT FROM AUTHOR]

Research on the existence of various elements in the universe has been extensive, but their role in the human body is not fully understood. About 98% of the human body mass consists of nine non-metallic elements, categorized into abundant and non-abundant/trace elements. Micronutrients, including trace elements, vitamins, and antioxidants, play a vital role in regenerative processes, coping with oxidative stress, and providing immunity against pathogens. Dental health is also dependent on these nutrients, which help in the production and development of oral mucosa, teeth, and surrounding tissues. The recommended intake of these nutrients remains variable due to factors such as geography, altitude, age, weight, physiological needs, pathological backlogs, and other recognizable/unrecognizable factors. Essential trace elements are broadly categorized into macro-elements, micro-elements or trace elements, probably essential elements, and potentially toxic elements. The current review focuses on the role of essential trace elements in maintaining oral health and their implications in various oral diseases and disorders. [ABSTRACT FROM AUTHOR]

The research aimed at 1- Studying the development of the daily per capita daily food, protein and calories from their various sources (plant and animal) intake from the daily food per capita in Egypt during the period (2010-2022),2- Estimating the nutritional content of protein and calories intake from daily food of the individual in study sample, 3- Studying impact of the most important economic and social factors on the daily per capita share of both protein and energy intake from daily food of the individual from its various sources for the study sample, and the study was based on methods Descriptive and quantitative analysis of the variables study, study relied on two types of data, the first of which is published secondary data (Food Balance Bulletin) to identify the evolution of the Egyptian per capita food components, as an indicator to study the nutritional situation and the economic situation of the family and individuals in the Egyptian countryside, and the primary data collected through a questionnaire form for the year 2024, for a sample from the countryside of Sharkia Governorate. The results showed that the average per capita total protein per day amounted to about 105 grams, with an annual decrease rate of about 0.85% of the average annual per capita during the study period, and by studying the average daily intake of protein per person from an animal source per gram, it was found that it amounted to about (26 grams) / day, which is equivalent to about 25% of the total protein intake per day during the period (2010-2022), 74% of the recommended, but it is still less than the recommended limit By the competent organizations (food and agriculture, and global health) which is 35 grams/day animal protein, and this would require finding appropriate solutions to ensure that the individual obtains the recommended amounts of animal protein because it contains the essential amino acids necessary for building body, especially for the most needy age groups such as children in the growth stage, and pregnant women, in order to avoid malnutrition in addition to many diseases resulting from the lack of these acids. As for the field sample, it was found that the individual in study sample gets only 70% of his needs of the total protein in his daily diet (49 grams), and shows the deficit in animal protein (17 grams), which is the most important in terms of health for the body, as the individual eats half of his daily needs, due to the low income, and the high price of animal protein sources, which would necessitate the development of a mechanism to provide these goods to the individual to achieve food security for him, study shown also the most important factors affecting per capita intake of protein and energy in study sample that each of the economic factors such as expenditure has a statistically significant impact on per capita intake of protein and energy intake daily at a significant level of 1%, and difference in income levels has a statistically significant impact on per capita intake of animal and plant protein for the upper income group only at a significant level of 1%, and statistically significant for the capita intake of energy from its sources and total energy at 1% for the category The upper income, and moral at 5% for middle income category, and some social factors such as family size have statistically significant impact on the per capita intake of protein and total energy and from their various sources, and the difference in level of education has a significant impact on the per capita intake of animal and plant protein at a moral level of 1% for the higher education category and for total energy and from both sources at a moral level of 1% for the higher education category only, which requires attention to the economic situation and improving level of income for the sample families to ensure the status of Good food for them. [ABSTRACT FROM AUTHOR]

Background: Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis. The countries with the third highest TB cases worldwide are India, China, and Indonesia. A decrease in stamina will occur in a person suffering from tuberculosis. Purpose: This study was conducted to determine the relationship between nutritional status and suspected new TB cases in junior high school students in the working area of Puskesmas Keputih Surabaya. Methods: This study was conducted with a cross-sectional study design in the working area of Puskesmas Keputih in 2023. Secondary data was obtained from Keputih Health Centre in 2023. The research sample used a total sampling population. The association between nutritional status and suspected new TB cases in junior high school students was tested using the chi-square method. Results: A chi-square test was conducted on high school students and found no significant association between nutritional status (underweight and average weight) and TB screening or suspected new TB cases (PR = 0.68, p-value = 0.16). In addition, it was also found that there was no significant association between nutritional status (overweight and average weight) and TB screening or suspected new TB cases (PR = 1.01, p-value = 1.00). Conclusion: There was no significant association between nutritional status and the incidence of new suspected tuberculosis in junior high school students. This indicates that other risk factors also play an essential role in influencing a person's immune system. [ABSTRACT FROM AUTHOR]

To examine the relationship between the energy-adjusted dietary inflammatory index (E-DII) and nutritional status, anthropometric measurements, subjective global evaluations (SGA) and biochemical parameters of chronic kidney disease patients. Cross-sectional analyses were performed on data collected from individuals. Participants included 119 adults aged 19 years and older, who had data from at least three days of valid 24-hour dietary recall data. Main outcome measures nutritional status, anthropometric measurements, SGA and biochemical parameters were collected. Statistical analyses performed Mann–Whitney U test, ANOVA, Kruskal–Wallis and ANCOVA test was used. It was determined that 79.8% of the patients were well-nourished, 19.3% had moderate malnutrition, and 0.9% had severe malnutrition. The patients with severe malnutrition was in the last quartile. It was determined that macronutrients and all vitamin and mineral intakes decreased in the last quartile values compared to the first quartile values (P < 0.05). After adjustment for age, sex, energy intake and glomerular filtration rat, there was a significant differences in triceps skinfold thickness and body fat percentage among the four quartiles. There was an increase in the C reactive protein levels from the first quartile to the third quartile (P < 0.05). This study shows that E-DII is a good tool for assessing the overall inflammatory potential of diet in chronic kidney disease patients. [ABSTRACT FROM AUTHOR]

Objective: in recent years, bariatric surgery has gained popularity as a treatment for obesity worldwide. While patients do experience weight loss after surgery, it is important to be aware that serious nutritional deficiencies may also occur. This study was conducted to evaluate the nutritional status of morbidly obese patients in the first six months after sleeve gastrectomy. Methods: the study was planned as a retrospective study. The data of 76 patients aged 19-64 years who had undergone bariatric surgery and were followed by a dietitian for at least 6 months were included in the study. Preoperative and postoperative biochemical parameters and anthropometric measurements of the patients were taken. Results: the lowest body weight of the patients was found at postoperative month 6 (81.74 ± 14.83 kg), the body weight at the preoperative period (115.86 ± 21.28 kg) and postoperative month 1 (100.39 ± 18.28 kg), and the body weight at postoperative month 1 was statistically lower than at the preoperative period. The preoperative body weights and BMI values of the patients were higher than at postoperative months 1 and 6, and the postoperative month 1 values were higher than at postoperative month 6 (p < 0.05). The lowest fasting blood glucose (83.48 ± 8.44 mg/dL), HbA1c (4.96 ± 0.95 %), and Homa-IR (3.34 ± 0.92) were observed at the postoperative month 6. Compared with the preoperative period, the iron level of the patients increased from 69.54 ± 29.82 µg/dL to 96.52 ± 25.39 µg/dL in postoperative month 6, vitamin D levels from 14.48 ± 8.70 µg/dL to 23.96 ± 4.79 µg/dL. While preoperative blood triglyceride and LDL values were statistically higher than in postoperative months 1 and 6, the HDL value was lower (p < 0.05). [ABSTRACT FROM AUTHOR]

Introduction: nutritional interventions (NI) in schoolchildren allow to take action in health promotion, physical activity, and nutrition actions for the prevention of malnutrition. Objective: to evaluate the effect of an NI on the nutrient content in school snacks (SS) in public education schools in Mexico. Methods: descriptive, longitudinal, and prospective study with a sample of 812 children were classified into intervention group (IG) and control group (CG). Anthropometric measurements (weight, height, waist circumference) were made to identify nutritional status (NS); to evaluate the SS, the food and beverages that the children took from home to consume during the break were recorded on a checklist; the NI was performed in the IG for 12 weeks with a 6-week reinforcement and the final evaluation was carried out that included NS and overweight (OW) in both groups. Results: a 1.4 % increase in overweight (OW) and obesity (OB) was observed in the IG, while in the CG it increased 5.5 %. In the SS, the CG showed a higher consumption of calories, carbohydrates, and sugars. In the intragroup analysis, the IG decreased carbohydrates, sugars. This intervention showed a small effect on the decrease of calories, carbohydrates and polyunsaturated acids of the IG compared to the CG. Conclusion: NI had a positive effect on the decrease in the energy and carbohydrate content of school snacks and therefore a slower trend in the prevalence of OW and OB in the IG compared to the CG. [ABSTRACT FROM AUTHOR]

Introduction: Adjuvant chemotherapy (AC) after radical surgery following preoperative chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC) is now the standard of care. The identification of risk factors for the discontinuation of AC is important for further improvements in survival. We herein examined the prognostic impact of chemotherapy compliance and its relationship with the prognostic nutritional index (PNI) before surgery. Methods: A total of 335 stage II–III LARC patients who underwent preoperative CRT between 2003 and 2022 at the University of Tokyo Hospital were retrospectively reviewed. We excluded patients with recurrence during AC and those who had not received AC. The relationship between AC and long-term outcomes and that between PNI values and the duration of AC were examined. Results: Thirty-one patients discontinued AC and 62 continued AC. Recurrence-free survival (RFS) was significantly shorter in patients who discontinued AC (p = 0.0056). The discontinuation of AC was identified as an independent risk factor for RFS (hazard ratio [HR]: 2.24, p = 0.0233). Twenty-one patients were classified as having low PNI (less than 40), which correlated with an older age, low body mass index, and incomplete AC. Low PNI was an independent risk factor for a shorter duration of AC (HR: 2.53, p = 0.0123). Conclusion: The discontinuation of AC was related to poor RFS in patients with LARC undergoing preoperative CRT. Furthermore, a low PNI value was identified as a risk factor for a shorter duration of AC. [ABSTRACT FROM AUTHOR]

Background: Food selectivity (FS), accompanied by nutritional inadequacies, is a common complaint in children with autism spectrum disorder (ASD). The impact of FS on bone mineral density (BMD) in children with ASD and FS, however, is not well documented. We evaluated the feasibility of assessing BMD in children with ASD. The sample included children with mild FS and children with moderate or greater FS. We also explored the impact of FS on BMD. Method: Boys with ASD (N = 20, age = 8.4 ±1.47 years) were divided into two groups: 10 mild FS and 10 moderate/severe FS. Dual-energy X-ray absorptiometry (DXA) measured total body (less head) and lumbar spine BMD. BMD Z-scores used reference datasets adjusted for height-for-age (HAZ). Biochemical indices and intake of calcium and vitamin D were collected. Pearson correlations examined associations, and t tests examined group differences in diet, biochemical indices, and BMD. Results: Of the children enrolled, 85% (17 of 20) completed the DXA lumbar spine scan, and 70% (14 of 20) completed the DXA total body scan. No associations among biochemical markers of 25-OH vitamin D and calcium were identified in the full sample. Total body BMDHAZ Z-scores were positively correlated with calcium intake in the mild FS group (r = 0.89, p = 0.017) and negatively correlated with vitamin D intake in the moderate/severe FS group (r = -0.93, p = 0.022). Unadjusted total body BMD Z-scores were lower in the moderate/severe FS group compared to the mild FS group (t = 2.30, p = 0.040). Conclusions: The collection of completed and usable DXA scans supports the feasibility of using DXA scans to measure BMD in children with ASD and FS. A larger study of children with ASD compared to non-ASD controls is needed to examine the impact of FS on BMD. [ABSTRACT FROM AUTHOR]

This study was conducted to evaluate the effects of selenium (Se) supplementation on growth performance of growing Awassi lambs. Twenty-five lambs were divided randomly into three groups. Lambs received the basal diet plus: no Se (CON; n = 8), 0.15 mg/lambs/day of supplemental Se to the diet as Se selenite (DSE; n = 8), or 0.5 mg/lamb of Se injection as Se selenite (ISE; n = 9). At the end of the study that lasted for 50 day, 3 lambs from each treatment randomly selected and individually housed in metabolism crates to evaluate nutrient digestibility. Nutrients (DM, OM, CP, NDF, ADF, and EE) intake of lambs and nutrient digestibility were not affected by Se supplementation. Growth performance (final body weight, average daily gain, and feed conversion ratio) of lambs were similar among treatment groups. Selenium supplementation (dietary or injection) failed to improve the performance of growing Awassi lambs fed high-concentrate diets containing 0.13 mg Se/kg of dry matter. [ABSTRACT FROM AUTHOR]