1. Analysis of Virological, Histological and Clinical Features of Hepatitis Delta Virus Infection in Southeastern Turkey
- Author
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Kendal Yalçin, Mehmet Suat Yalçın, [Yalcin, Mehmet Suat -- Yalcin, Kendal] Dicle Univ, Fac Med, Dept Internal Med, Div Gastroenterol & Hepatol, Diyarbakir, Turkey, and Yalcin, Mehmet Suat -- 0000-0003-1054-1882
- Subjects
lcsh:Internal medicine ,cirrhosis ,HEPATITIS DELTA ,lcsh:R ,lcsh:Medicine ,Biology ,Virology ,Virus ,lcsh:Infectious and parasitic diseases ,Hepatitis delta virus ,lcsh:RC109-216 ,lcsh:RC31-1245 ,hepatitis B virus ,liver biopsy - Abstract
WOS: 000441968900004, Objectives: The present study aims to investigate biochemical, virological and histological characteristics of hepatitis delta virus infection, which is a serious problem in our region, as well as its relationship with chronic hepatitis B virus (HBV) infection and cirrhosis. Materials and Methods: A total of 220 patients were included in the study. The patients were divided into three groups: group 1 included patients with hepatitis delta virus-related cirrhosis (DA cirrhosis), group 2 consisted of patients with chronic delta hepatitis (CHD) and group 3 composed of patients with chronic hepatitis B (CHB). Biochemical and virological parameters of the patients were analyzed. Patients with CHB and CHD underwent biopsy for histological examination. The results were compared among the three groups. Results: Seventy-five (34.09%) of the patients were women, 145 (65.90%) were males and their mean age was 38.04 years. There were 44 patients (20%) with delta hepatitis-associated cirrhosis, 86 patients with CHD (39.09%) and 90 patients with CHD (40.9%). HBV DNA level was significantly lower in patients with cirrhosis and chronic delta hepatitis than in patients with CHB (p
- Published
- 2018