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Copyright of Arid Zone Research / Ganhanqu Yanjiu is the property of Arid Zone Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tea, one of the significant export commodities in modern China, faced a continuous decline in its export during the late Qing Dynasty and Early Republic of China. In response to this predicament, tea merchants attempted to implement quality control measures in tea export, driven by market forces. During the initial stage of the Nanjing national government, the Ministry of Industry actively intervened in the quality management of tea export. It established specialized tea inspection agencies, developed uniform inspection standards, set normative inspection procedures, and adopted scientific inspection methods to conduct tea export inspections. Evidence illustrates that in the initial stage of the Nanjing national government, the tea export inspections yielded positive outcomes in improving tea quality and restoring the reputation of Chinese tea. However, with the full scale outbreak of the War of Resistance against Japanese Aggression, coupled with inherent deficiencies, tea export inspection practices in the early Nanjing national government failed to resolve the dilemma of tea exports in modern China. Nonetheless, viewed from a long-term perspective, it laid a solid foundation for the establishment of tea inspection systems in New China. [ABSTRACT FROM AUTHOR]

The carbonate rocks of the Tahe oilfield have the characteristics of "Two super-high and five high", that is, ultra-deep, super-thick, high viscosity, high temperature, high pressure, high hydrogen sulfide and high salinity, the lifting of crude oil is a major problem in the face of such unique features of domestic and world oil products, it is a key technology for heavy oil recovery in Tahe. This technology works well with annular blending and has a long pump inspection period. With the continuous development of oil fields, the number of large-scale electric equipment and electric pump wells is increasing, which has a great impact on the stability of the power grid. When the power grid fluctuates, the heavy oil pump stops, the heavy oil in the pump stops flowing, the temperature field established when the pump is steadily lifted loses gradually, the viscosity of crude oil increases sharply after the temperature drops, at this time, the starting motor load of the pump is too high, it is very easy to cause overload shutdown, which will cause the electric pump to lie down in the well when it is serious, resulting in production loss and affecting the mining benefit. In this paper, based on the analysis of the influence factors of power grid fluctuation, by adding buffer devices for starting and stopping on the high-power electrical equipment, for the measures of adding voltage regulator, remote intelligent start-stop control system of electric pump and adding capacitor compensation voltage regulator in frequency converter, the methods of preventing electric pump from stopping caused by power grid fluctuation are put forward systematically, it is of great significance to resist the smooth operation of heavy oil electric pump wells. [ABSTRACT FROM AUTHOR]

BACKGROUND: Estrogen deficiency can inhibit osteoclast proliferation and differentiation. Epimedium is a phytoestrogen that acts as a traditional kidney tonic herb, and its active ingredient, icariin, can produce some effects of estrogen. OBJECTIVE: To investigate the possible signaling pathways involved in the non-nuclear effects of icariin in promoting osteoblast proliferation and differentiation, as well as the possible mechanisms of phosphorylated protein cascade regulation in the signaling pathway by phosphorylated proteomics techniques. METHODS: Primary osteoblasts were obtained from newborn Sprague-Dawley rats, cultured, and identified. The effect of icariin on osteoblast activity was measured by cell counting kit-8 method. The primary osteoblasts were passed to the third generation. After 24 hours, passaged cells were then divided into six groups: bovine serum albumin intervention group, PBS intervention group, icariin intervention group, icariin-bovine serum albumin coupling intervention group, ICI182780+icariin-bovine serum albumin coupling intervention group, and PD98059+icariin-bovine serum albumin coupling intervention group. The cells of each group were collected at 0, 5, 15 and 25 minutes and used for protein extraction, enzymatic digestion, peptide labeling and phosphorylated peptide enrichment. Phosphoproteomic analysis was performed using liquid chromatography-mass spectrometry technology RESULTS AND CONCLUSION: 10 μg/L Icariin significantly promoted the proliferation and differentiation of osteoblasts. Icariin-bovine serum albumin coupling was able to induce phosphorylation of ERK in osteoblasts without membrane permeation, confirming the non-nuclear effect. Compared with the icariinbovine serum albumin coupling intervention group, there were 971 differentially expressed proteins (499 up-regulated and 472 down-regulated) in the icariin intervention group, 974 (509 up-regulated and 465 down-regulated) in the bovine serum albumin intervention group, 836 (377 up-regulated and 459 downregulated) in the PBS intervention group, 231 (126 up-regulated and 105 down-regulated) in the ICI182780+icariin-bovine serum albumin coupling intervention group, and 150 (65 up-regulated and 85 down-regulated ) in the PD98059+icariin-bovine serum albumin coupling intervention group. Among them, 65 and 62 significantly expressed proteins were down-regulated (Fc value < 0.8) in the ICI182780+icariin-bovine serum albumin coupling intervention group and PD98059+icariin-bovine serum albumin coupling intervention group, respectively, most of which were involved in important biological processes, such as mRNA processing and stability regulation, RNA splicing, protein phosphorylation, and mitosis, as well as in signaling pathways analyzed by KEGG library, such as MAPK, protein ubiquitination, mTOR, and PI3K/Akt pathways. To conclude, icariin promotes osteoblast proliferation and differentiation through non-nuclear effects in relation to MAPK, protein ubiquitination, mTOR, and PI3K/Akt signaling pathways. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of Botanical Research is the property of Bulletin of Botanical Research Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the clinical value of audio-visual response and CNV changes in children with attention deficit hyperactivity disorder (ADHD) . Methods A total of 90 ADHD children aged 7-12 years were selected and 30 healthy children were selected as controls. The Swanson, Nolan and Pelham-IV rating scales (SNAP-IV scale),the integrated visual and auditory continuous performance test (IVA-CPT) and CNV test were performed respectively. The X2 test and independent samples t test were used to verify the regularity of cognitive function in children with ADHD. Results (1) The difference of SNAP-IV scores between the two groups was statistically significant (P<0. 05) . (2) The differences of synthesis, audiovisual attention quotient and control quotient in IVA-CPT between the two groups were statistically significant (P<0. 05),and there were statistically significant differences in the ability of audio-visual attention concentration and retention between the two groups in undertaking assignment tasks (P<0. 05) . (3) There was no significant difference of CNV in the PINV latency between the two groups (P>0. 05) . In terms of PINV amplitude, ADHD group was significantly lower than control group and the difference was statistically significant (P<0. 05) . Conclusion (1) The performance of ADHD patients′ attention deficit/hyperactivity significantly affects their daily activities, and it is obvious to their parents. (2) The degree of concentration and retention of audio-visual attention and retention of ADHD patients in completing daily activities and learning-related homework tasks are significantly reduced. (3) The difference of CNV test in ADHD patients is mainly reflected in the amplitude. [ABSTRACT FROM AUTHOR]

[Objective] The distribution characteristics of particle size, magnetic susceptibility and environmentally sensitive grain size fractions of eolian sand sediments under different dune types in the oasis-desert ecotone were studied to explore the relevant parameters and distribution patterns of eolian sand sediments under different dune types. Methods] Based on the grain size data and susceptibility data of each part of the four kinds of sand dunes in the oasis-desert ecotone, the correlation analysis was carried out by using mathematical statistical method. [Results] The surface sand contents of the four types of dunes differ in different geomorphic areas, with the surface sand content of the four types of dunes consisting mainly of very coarse silty sand, very fine sand and fine sand, with the total percentage content of 96.71 %, 97.54%, 98.48% and 98.65%, respectively. All the four different dunes have moderately good sortability of surface sand material. The mean kurtosis values of the different dunes range from ().93 to 1.()2, which is a medium kurtosis. Tn general, the kurtosis values of the four dunes increase gradually from the bottom to the top of the windward slope and decrease from the top to the bottom of the leeward slope. The crescent-shaped dunes have the lowest kurtosis values, ranging from一().03 to ().()1, which are mainly symmetrical, while kurtosis values of the wind shadow, gyre and scrub range from 一 0. ()4 to 0. 44, which are mainly symmetrical and positively skewed. The mean grain sizes of sand material on the surface of wind shadow dunes, scrub dunes and crescent dunes show the highly significant positive correlation (p

The plastic deformation and numerous natural joints of shale pose a great challenge for the prediction of the hydraulic fracture geometry extension. Based on the finite element method, a fully coupled numerical model for elastoplastic hydraulic fractures was established with natural fractures and bedding planes considered. The numerical model was validated with the KGD analytical solution and Blanton's curve. The numerical results show that, compared with the numerical model solution of linear elasticity, the hydraulic fractures are prone to enter the natural weak interface due to the rock plastic deformation. The rock plastic deformation area mainly lies in the reservoir layer during the fracture propagation. In the case of rock ductile damage, the hydraulic fracture is more likely to penetrate the bedding plane. Hydraulic fractures can directly penetrate natural fractures and bedding planes at high injection rates due to large driving forces. The study provides new insights in terms of hydraulic fracture extension in elastoplastic formations. [ABSTRACT FROM AUTHOR]

Aerodynamic system is an important part of a grain cleaning equipment. In this paper, the literature classification method is used to classify and study the literature, and the application and research progress on aerodynamic technology in grain cleaning are analyzed and summarized, so as to provide reference and guidance for the application and development of aerodynamic grain cleaning technology. In order to achieve the goal of grain cleaning, the corresponding cleaning methods are adopted in different cleaning occasions. However, the air flow characteristics and grain particle characteristics have significant influence on the cleaning effect of grain cleaning based on aerodynamics. When the variation range of grain particle characteristics is certain, the adjustment amount of cleaning equipment and the feeding amount were unchanged, the factors affecting the cleaning efficiency of grain were counted. The distribution form, uniformity, and stability of aerodynamic field had a direct influence on the cleaning effect of grain. In the work of grain cleaning, the key of grain efficient sorting is to clarify the distribution law and influencing factors of air flow stability and uniformity in the aerodynamic field, clarify the action mechanism of grain grading weight, and ensure the uniformity and stability of the aerodynamic system and the match of the whole cleaning system. [ABSTRACT FROM AUTHOR]

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Rod pump oil production is the main force in the exploitation of heavy oil reservoirs in Tahe oilfield. With the continuous development of heavy oil, the intensity of water injection and gas injection increases. At the same time, both the viscosity of crude oil and the water content increase, and the energy decreases. The formation fluid output and properties fluctuate violently in production. The operating conditions of machine pumped wells are increasingly bad, and the measurement is extremely inaccurate, which makes the management extremely difficult. Because the wellhead parameters lag behind the changes of downhole working conditions, it is difficult to be prevented in advance in production, After the occurrence of anomalies, the best time for optimization and adjustment is often missed, resulting in frequent anomalies such as rod breakage, heavy oil backflow and gas lock, which seriously affects the production efficiency. Based on the understanding of Tahe heavy oil wellbore environment, the application of remote dynamometer monitoring technology in Tahe Oilfield is summarized and refined in this paper by deepening the application of remote dynamometer monitoring technology to improve the management level of mechanical pumping wells. The researcher innovatively puts forward the method of oil measurement of heavy oil well dynamometer to tackle the problem of inaccurate measurement of heavy oil wells. [ABSTRACT FROM AUTHOR]

Copyright of Piezoelectrics & Acoustooptics is the property of Piezoelectric & Acoustooptic and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Rubber Industry is the property of Editorial Office of China Rubber Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Northwest A & F University - Natural Science Edition is the property of Editorial Department of Journal of Northwest A&F University (Natural Science Edition) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Botanical Research is the property of Bulletin of Botanical Research Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Studies have shown that abnormal osteoblast metabolism may cause abnormal subchondral bone mineralization in knee osteoarthritis. OBJECTIVE: To verify the effects of catalpol from the root of Rehmannia glutinosa on osteoblast proliferation and drug toxicity, and the anti-inflammatory protective effect on inflammatory osteoblasts induced by lipopolysaccharide. METHODS: (1) Osteoblasts from newborn Sprague-Dawley rats were primarily extracted, cultured, and passaged. The activity and proliferation of osteoblasts were determined by observing the morphology of osteoblasts alkaline phosphatase staining and staining of mineralized nodules. (2) Cell counting kit-8 (CCK-8) method was used to observe the effect of different concentrations of catalpol from the root of Rehmannia glutinosa on osteoblast activity. (3) Different concentrations of lipopolysaccharide (0, 10, 20, 40, 80, 160 mg/L) were used to induce inflammatory osteoblasts in fetal rats. CCK-8 method was used to verify the best concentration. (4) The experiment was divided into three groups: blank group, model group, low-, medium- and high-concentration catalpol groups. Inflammatory osteoblasts were induced by lipopolysaccharide at 80 mg/L, and then treated for 8 hours. CCK-8 method was used to observe the effect of different concentrations of catalpol on inflammatory osteoblasts. The study protocol was approved by the Medical Ethics Committee of Liuhe District People’s Hospital in Nanjing. RESULTS AND CONCLUSION: When osteoblasts were cultured to the fourth generation, followed by alkaline phosphatase staining, black grey granules were found in the cytoplasm of the positive cells, and the morphology of the cells was irregular. When the concentration of catalpol was lower than 1 mg/L, it had no significant effect on osteoblasts; when it was higher than 10 mg/L, it had a significant effect on the proliferation of osteoblasts but no drug toxicity (P < 0.05). When the concentration of lipopolysaccharide was higher than 80 mg/L, there was a significant trend of inflammatory damage to osteoblasts (P < 0.01). Therefore, 80 mg/L was selected as the best injury concentration in this experiment. When the concentration of catalpol from the root of Rehmannia glutinosa was lower than 1 mg/L, it had no significant protective effect on the inflammatory response of osteoblasts (P < 0.05); when it was higher than 10 mg/L, it had significant protective effect on the inflammatory response of osteoblasts (P < 0.05). Therefore, when the concentration of catalpol from the root of Rehmannia glutinosa reaches a certain level, it has no toxic effect on osteoblasts, promotes proliferation, and has anti-inflammatory protective effect on inflammatory osteoblasts induced by lipopolysaccharide. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Papain inducing knee osteoarthritis has no direct effect on collagen and chondrocyte compared with other chemical inducers. OBJECTIVE: To evaluate the effectiveness of early osteoarthritis model of knee joint in rats by the surface morphology, radiology and histopathology of cartilage. METHODS: Twenty adult male Wistar rats were provided by Qinglongshan Animal Breeding Farm of Jiangning District, Nanjing, and the study was approved by the Ethics Committee of Liuhe Hospital Affiliated to Yangzhou University Medical College. The rats were randomly divided into control and experimental groups. At 1, 4 and 7 days, 4% normal saline and 4% papain were injected into the rat right knee joint cavity in the control and experimental groups, respectively. Rats were killed at 10 days. The articular cartilage morphology,X-ray and three-dimensional CT images were observed before the execution. Histopathological examination was performed immediately after the execution, and the results were verified by Mankins and OARSI scores. RESULTS AND CONCLUSION: (1) Compared with the control group, in the experimental group, the limp was obvious, the knee joint swelling on the injection side was obvious, and the hind limbs were unwilling to land. Radiological examination showed that the joint space narrowed obviously, and the value of three-dimensional CT joint space was significantly decreased [(0.680 0±0.016 3)vs.(0.558 0±0.033 9) mm, P < 0.05]. (2) Microscopic examination showed early stage inflammation characteristics at the right knee joint in the experimental group. There were significant differences in the Mankins and OARSI scores (P < 0.05). (3) In summary, early knee osteoarthritis induced by intra-articular injection of papain into the right knee joint of rats can be used in relevant clinical studies, because it provides measurable changes in joint motion, tactile abnormal pain, progressive radiodegeneration and micro-inflammation of articular cartilage, representing the evaluation of osteoarthritis, and providing a basis for studying the pathogenesis of early knee osteoarthritis. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Application Research of Computers / Jisuanji Yingyong Yanjiu is the property of Application Research of Computers Edition and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Northeastern University (Social Science) / Dongbei Daxue Xuebao (Shehui Kexue Ban) is the property of Dongbei Daxue and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Northeastern University (Natural Science) is the property of Dongbei Daxue Xuebao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

At present, traditional imaging techniques for the diagnosis of early - stage pancreatic cancer lack enough sensitivity, and therefore, early diagnosis of pancreatic cancer is still the biggest challenge in precision medicine around the world. Based on a large amount of clinical practice and the development of related techniques, endoscopic ultrasonography (EUS) gradually shows its advantages in the diagnosis of pancreatic cancer, especially early diagnosis. This article reviews the application of EUS in the early diagnosis of pancreatic cancer and related research advances. [ABSTRACT FROM AUTHOR]