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Copyright of Chinese Journal of Bioprocess Engineering is the property of Chinese Journal of Bioprocess Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Liquid Crystal & Displays is the property of Chinese Journal of Liquid Crystal & Displays and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To explore the mechanism of Shaoyao Gancao decoction in the treatment of hyperprolactinemia (HPRL) based on network pharmacology. METHODS: The main active ingredients and targets of radix paeoniae alba and licorice were screened by traditional Chinese medicine systems pharmacology database and analysis platform. GeneCards, DisGeNET, Online Mendelian Inheritance in Man and Drugbank databases were used to predict the related targets of HPRL. Venny 2. 1 online tool was used to draw Venn diagram. Protein-protein interaction (PPI) network was created by using STRING database for PPI analysis. Cytoscape 3. 7. 1 software was used to construct “drug-ingredient-target-disease” network. Potential targets were analyzed by Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analysis and gene ontology (GO) functional enrichment analysis in DAVID database. Molecular docking verification of main active ingredients and core targets was carried out by Autodock. RESULTS: A total of 102 active ingredients were obtained, and the main active ingredients related to HPRL were quercetin, kaempferol and formononetin. Totally 35 targets related to Shaoyao Gancao decoction and HPRL were obtained by the intersection, the core targets mainly included ESR1, ADRA1B and KDR, etc. GO functional enrichment analysis revealed 122 biological processes, mainly related to the positive regulation of nitric oxide biosynthetic process, and the response to ethanol. Enrichment analysis of KEGG pathway found 40 pathways, mainly FoxO, hypoxia inducible factor-1, prolactin signaling pathway, Janus kinase / signal transduction and transcription activator, phosphatidylinositol-3-kinase / protein kinase B, and mitogen-activated protein kinases and other signaling pathways. Molecular docking showed that the main active ingredients had good binding ability to the core target. CONCLUSIONS: This study preliminarily reveals the mechanism of multi-ingredient, multi-target and multi-path mechanism of Shaoyao Gancao decoction in the treatment of HPRL, which provides theoretical basis for further experimental research. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao is the property of Journal of Nanjing Agricultural University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To retrospectively evaluate the safety and efficacy of percutaneous thermal ablation combined with simultaneous transarterial chemoembolization (TACE) for advanced intrahepatic cholangiocarcinoma (ICC). Methods From Jun., 2010 to Mar., 2017, a total of 53 patients with advanced ICC who underwent percutaneous thermal ablation combined with simultaneous TACE in Zhongshan Hospital, Fudan University were enrolled in this study. Their clinical data were collected and reviewed. The tumor response was assessed according to mRECIST criteria. The treatment-related complications, overall survival (OS), progression-free survival (PFS) and prognostic factors were analyzed by SPSS 24. Results The response rate (RR) was 80.7% and the median PFS and the median OS were 7.2 and 20.9 months, respectively. The cumulative survival rates at 1, 2, and 3 years were 72.6%, 39.1% and 24.3%. The cumulative progression-free survival rates at 6, 12, and 18 months were 58.3%,40.4% and 24.2%. Child-Pugh classification was a prognostic factor in patients with advanced ICC who were treated with percutaneous thermal ablation combined with simultaneous TACE. The vagal reflex during procedure occurred in 1 patient, and liver abscesses after treatment happened in 2 patients, while no treatment-related deaths were observed. Conclusions This study demonstrates that percutaneous thermal ablation combined with simultaneous TACE is safe and effective for advanced ICC. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To probe into the entry points and methods of pharmaceutical care for patients with abdominal infection after biliary tract surgery by clinical pharmacists, so as to provide references for the comprehensive analysis and treatment of postoperative secondary infections. METHODS: Clinical pharmacists participated in the whole course of treatment on a patient with abdominal infection after biliary tract surgery, learned about the underlying disease, clinical symptoms, laboratory test results and medication history of patients, analyzed the pathogenic bacteria of postoperative infection and assisted clinicians in formulating individualized therapeutic regimen with the combination of high risk factors of abdominal infection. RESULTS: Through comprehensive analysis, it was concluded that the pathogenic bacteria induced abdominal infection were mainly Pseudomonas aeruginosa, anaerobic bacteria and enterococcus, which can be effectively covered by cefoperazone sulbactam, ornidazole and linezolid, so that the infection was controlled in time. CONCLUSION: Clinical pharmacists have applied pharmaceutical knowledge and clinical experience to participate in the formulating of anti-infective individualized therapeutic regimen on providing effective pharmaceutical services for patients and medical staff. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Diagnostic Imaging & Interventional Radiology is the property of Editorial Office of Diagnostic Imaging & Interventional Radiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)