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This paper summarized the nursing management for a patient with intertrochanteric fracture combined with pressure injuries in the left buttocks. Effective treatment plan was made based on the nursing evaluation of stage of pressure injuries. Wound dressing material and dressing change methods were carefully considered according to the different phases of wound healing. Targeted nursing interventions were carried out to improve the wound healing of the patient with pressure injuries. (本文总结1例股骨粗隆间骨折合并左臀部压力性损伤的护理经验。正确评估压力性损伤的等级, 给予有效的治疗措施, 并根据患者创面的变化, 选取适合的换药方式, 应用正确的创面敷料, 有针对性地进行护理干预, 有助于促进压力性损伤的愈合。)

BACKGROUND: Studies have shown that short-chain fatty acids (SCFAs) are a potential regulator of skeletal muscle energy metabolism, but the exact mechanism is unclear. OBJECTIVE: To observe the effect of SCFAs on aged rats with sarcopenia and to explore the underlying mechanism. METHODS: Sprague-Dawley rats were randomly divided into control group, sarcopenia group, and sarcopenia + SCFAs group (SCFAs group). In the latter two groups, rat models of sarcopenia were established using ovariectomized rats injected with 5 mg/kg dexamethasone for 7 days. In the control group, the abdominal cavity was only exposed but not removed, and then sutured. Rats in the SCFAs group were administered drinking water containing 150 mmol/L short-chain fatty acids, 600 mg/kg sodium acetate, 200 mg/kg sodium propionate, and 200 mg/kg sodium butyrate for 4 weeks. Rats in the control and sarcopenia groups were given the same volume of normal saline. Successful modeling was assessed by measuring the bilateral gastrocnemius muscle mass and body mass to calculate the gastrocnemius index after modeling. Food intake, body mass and grip strength of rats were measured at 0, 1, 2 and 4 weeks after successful modeling; morphological changes of gastrocnemius muscle were observed by hematoxylin-eosin staining; and the expression of p-AMPK and p-ULK1 proteins in gastrocnemius muscle was detected by western blot. RESULTS AND CONCLUSION: Compared with the control group, the sarcopenia group showed significantly decreased body mass, food intake, forelimb grip strength (P < 0.05), wet mass of gastrocnemius muscle (P < 0.05), and protein levels of p-AMPK and p-ULK1 (P < 0.05). Compared with the sarcopenia group, the SCFAs group showed a significant increase in food intake, body mass, grip strength, wet mass of gastrocnemius muscle, and protein levels of p-AMPK and p-ULK1 in gastrocnemius muscle (P < 0.05). All these findings indicate that SCFAs improve symptoms of sarcopenia in the elderly and may be associated with the upregulation of AMPK and ULK1 proteins in skeletal muscle. [ABSTRACT FROM AUTHOR]

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Objective Based on the Gene Expression Omnibus （GEO） database, our aim is to identify potential mitophagy-related genes for sarcopenia and to observe their expression changes in skeletal muscle tissues of patients with sarcopenia. Methods Gene expression datasets for sarcopenia （GSE1428） were obtained from the GEO database and differentially expressed genes （DEGs） in the sarcopenia samples and normal samples were screened. The DEGs of sarcopenia were intersected with mitophagy-related genes using the "VennDiagram" package to obtain mitophagy-related DEGs of sarcopenia. The biological functions of mitophagy-related DEGs for sarcopenia were analyzed using Gene Ontology （GO） and Kyoto Encyclopedia of Genes and Genomes （KEGG). The mitophagy-related target genes for sarcopenia were selected using Cytoscape, and the expression changes of these genes in skeletal muscle tissues of patients with sarcopenia and controls were observed in the gene expression datasets GSE136344 for sarcopenia. Results Ninety-nine mitophagy-DEGs for sarcopenia were screened out. As shown by KEGG enrichment analyses, these genes were significantly enriched in pathways responsible for neurodegeneration-multiple diseases, Parkinson's disease, prion disease, and so on. GO function annotation showed that DEGs were mostly located in the mitochondrial inner membrane and mitochondrial protein-containing complex, where they were engaged in biological processes such as energy metabolism, cellular respiration, and oxidative phosphorylation. They were also involved in the molecular functions of active transmembrane transporter activity, etc. The inner membrane mitochondrial protein （IMMT), dynamin 1-like （DNM1L), and ATP5A1 were identified as the mitophagy-related target genes for sarcopenia. Sarcopenic patients exhibited lower expression levels of IMMT and DNM1L in their skeletal muscles in comparison with non-sarcopenic individuals （all P<0. 05). Conclusions IMMT and DNM1L were identified as significant mitophagy-related target genes for sarcopenia. These target genes contributed to the pathogenesis of Sarcopenia not on‐ ly by affecting neurodegeneration-multiple diseases pathways, Parkinson's disease pathway, and prion disease pathway but also by participating in biological processes such as energy metabolism, cellular respiration, and oxidative phosphorylation. Patients with sarcopenia exhibited lower expression levels of IMMT and DNM1L in skeletal muscle tissues. [ABSTRACT FROM AUTHOR]

Copyright of Acta Geoscientica Sinica is the property of Acta Geoscientica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Geoscientica Sinica is the property of Acta Geoscientica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study was carried out to investigate the impact of two litter remaining characteristics of six typical vegetation communities in urban green spaces on the physicochemical properties of the soil. Typical vegetation communities in Yuantouzhu Park were selected as the research area, and the litter amounts of those vegetation communities in the urban green spaces and their responses to the soil physicochemical properties were studied. The results showed that the annual litter amounts of the tree-shrub-ground cover, tree-lawn, tree-ground cover, and tree-shrub-lawn communities were significantly higher (P<0.05) than those of the shrub-ground cover and shrub-lawn communities. The litter standing stock, total soil porosity, non-capillary porosity, and soil organic matter, total N, and hydrolyzed N contents of the coverage from the tree-shrub-ground cover, tree-ground cover, and shrub-ground cover communities were all significantly higher than those of the coverage from the tree-shrub-lawn, tree-lawn, and shrub, lawn communities. Soil bulk density of tree-shrub-ground cover, tree-ground cover, and shrub-ground cover communities were all significantly lower than it of tree-shrub-lawn, tree-lawn, and shrub-lawn communities. Although there were some significant differences in the soil capillary porosity, pH value, and total P content among the six communities, there were no differences in the total K and available K contents. According to the correlation analysis, the annual litter in the communities had no correlation with the indicators of the physicochemical properties of soil at 0-10 cm. By contrast, the litter standing stock was closely related to the soil physicochemical properties, that is, its value was significantly negatively correlated with the soil bulk density (P<0.01) and pH value (P<0.05) and significantly positively correlated with the total soil porosity, non-capillary porosity, soil organic matter, total N content, hydrolyzed N value (P<0.01), and available K content (P<0.05) and had no correlation with the soil capillary porosity and total P and total K contents. These results indicated that litter on the surface cover of urban green spaces can directly or indirectly improve the soil physicochemical properties as well as the soil water holding capacity and permeability. Increasing soil organic matter and N contents can also improve the soil pH value. [ABSTRACT FROM AUTHOR]

目的 探讨慢性肾脏病管理模式对慢性肾脏病伴高尿酸血症患者的影响。方法 选取该院 2016 年 4 月至2017 年 4 月收治的82例慢性肾脏病伴高尿酸血症患者进行分组比较,给予慢性肾脏病管理模式者纳入观察组,给予常规疾病管理者 纳入对照组,每组各 41 例。结果 干预后, 2 组尿酸水平均有所下降, 且观察组的尿酸水平显著低于对照组,差异有统计学意义 (P <0.05)。干预后,观察组的高嘌呤饮食者比例均显著低于对照组, 且观察组的运动者比例显著高于对照组, 差异有统计学意 义(P <0.05)。干预后观察组的肌酐、尿素氮及 24 h 尿蛋白定量与对照组相比具有明显改善,差异有统计学意义 (P <0.05)。结 论 临床将慢性肾脏病管理模式应用到慢性肾脏病伴高尿酸血症患者护理管理工作中, 可提升患者自我管理水平, 纠正不良生活 习惯,故有进一步推广的价值。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Mechanical & Electrical Engineering is the property of Mechanical & Electrical Engineering Magazine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Capital Institute of Physical Education is the property of Shoudu Tiyu Xueyuan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨同伴教育在护理学基础技能培训中的应用及效果。 方法 选取该校2013级高职护理专业（普招班）11个班中随机抽取2个班116名学生作为研究对象，将其分为实验组和对照组，各58名。实验组学生采取同伴教育法，对照组采用传统教学法。操作复习后进行技能考核，对考核效果进行评价。 结果 实验组学生操作考核成绩明显优于对照组，差异有统计学意义（χ2=19.90，P<0.01）；且实验组学生各项目成绩均明显高于对照组，差异均有统计学意义（P<0.05）。 结论 在护理学基础技能培训中使用同伴教育法，可取得良好的教学效果，也可激发学生的学习积极性，提高沟通能力及团队合作精神。 [ABSTRACT FROM AUTHOR]