Search

Objective To study the effect and clinical value of supervised quitting smoking and lung rehabilitation on patients with chronic obstructive pulmonary smoking. Methods The general data and pulmonary function indexes of male patients with chronic obstructive pulmonary disease （COPD） who had been hospitalized in our department from June 2018 to August 2019 were collected. According to the principle of order， they were randomly divided into control group and supervised group. The differences of general data， lung function indexes （1 week，half year） and smoking expenditure were compared. Results After six months of follow-up， the number of cigarrette [supervised group （11±11.995） and control group （17.1±11.784） ] decreased， and the difference was statistically significant （ ＜0.05） . Half a year later， compared with the two groups， the supervised group smoked much less than the control group， and the difference was statistically significant （ ＜0.05） . Estimated FEV1 （%） [supervised group （71.14±14.077%） and control group （65.20±14.028%） ] were different， with statistically significant difference （ ＜0.05） . Half a year later， compared with the two groups， the supervised group was superior to the control group， and the difference was statistically significant （ ＜0.05） . FEV 1 （supervised group supervised group 1.656 ±0.4708） L， control group （1.462 ±0.4637） L） showed no significant difference （ ＞0.05） . The control group decreased，and the difference was not statistically significant （ ＞0.05） . Half a year later， the difference between the two groups was statistically significant （ < 0.05） . FVC [supervised group （3.0144±0.5326） L， control group （2.9118±0.5048） L] in the supervised group increased， control group decreased，and the difference was not statistically significant （ ＞0.05） . Six months later， there was no significant difference between the two groups （ > 0.05） . Conclusion The supervision of quitting smoking and lung rehabilitation in patients with smoking COPD can reduce the number of cigarette， improve the success rate of quitting smoking， delay and even improve the pulmonary function of some patients， and the clinical effect is remarkable. [ABSTRACT FROM AUTHOR]

Objective To study the efficacy and safety of bronchoalveolar lavage in the treatment of patients with severe CAP．Methods 76 patients with severe CAP were selected fromAugust，2016 to November，2018 in Ganmei Hospital Affiliated to Kunming Medical University(The First People's Hospital of Kunming) .All patients were randomly divided into 2 groups:treatment group (n = 38) and control group (n = 38) .The treatment group was treated with bronchoscopy and alveolar lavage. After 7 days， body temperature fluctuation， white blood cell， blood gas analysis (PaO2 and PaCO2) and total hospitalization time were observed.At the same time，we observedwhether there were serious adverse events during hospitalization in the two groups．Results After treatment， body temperature[treatment group(37.082±0.7822)℃，control group (37.603±0.7779) ℃]， white blood cell[treatment group (9.058±1.8232) ×109，control group (11.41±.0599) ×109] and PaCO2[treatment group (42.84±6.092) mmHg，control group (48.63±6.162) mmHg] were decreased in the two groups，and the difference was statistically significant(P<0.05) .At the same time， the effect of bronchofiberscope lavage in the treatment group was more significant， and the decrease was more obvious， the difference was statistically significant (P<0.05) .After treatment， PaO2 [treatment group(82.12±8.867) mmHg，control group (67.87± 9.154) mmHg ]increased， and the difference was statistically significant compared with that before treatment( < 0.05) .At the same time， the curative effect of bronchoscopy lavage in the treatment group was better and the increase was more significant than the control group，the difference was statistically significant(P<0.05) .Hospitalization time [treatment group (13.97±3.537) d，control group (20.19±3.763) d]of patients in the treatment group was shorter than that in the control gorup， the difference was statistically significant(P<0.05) ．Conclusion Bronchoscope alveolar lavage has significant clinical effect and no serious adverse reactions in the treatment of patients with severe CAP. [ABSTRACT FROM AUTHOR]