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BACKGROUND: Agomelatine is a clinically proven treatment for neuropsychiatric symptoms, such as anxiety and depression. Furthermore, our previous study has demonstrated that agomelatine ameliorates cognitive behaviors, hippocampal synaptic plasticity, and brain pathology in a mouse model of Alzheimer’s disease. However, it remains unclear whether agomelatine can improve anxiety and depression-like behaviors in Alzheimer’s disease model mice. OBJECTIVE: To investigate the improving effects of agomelatine on anxiety- and depression-like behaviors in APP/PS1 transgenic mice and its underlying molecular mechanisms. METHODS: (1) Eighteen APP/PS1 transgenic mice were randomly divided into model control group (n=9) and model intervention group (n=9). Another wildtype mice were randomized into control group (n=9) and intervention group (n=9). Model intervention group and intervention group were intraperitoneally injected with 10 mg/kg agomelatine per day for 31 continuous days. Behavioral experiments, including the elevated cross maze and forced swimming tests, and mRNA sequencing of the hippocampus were then performed. (2) Mouse hippocampal neuronal cell lines (HT22) and brain microvascular endothelial cell lines (bEnd.3) were cultured and divided into four groups: blank group without any drug, drug group with 20 µmol/L agomelatine, model group with 10 µmol/L β-amyloid 1-42, and experimental group with 10 µmol/L β-amyloid 1-42+20 µmol /L agomelatine. After 24 hours of incubation, protein expression of S416p-tau and S9p-GSK3β in HT22 cells was detected by immunoblotting, and protein expression of low-density lipoprotein receptor-related protein 1 and glycosylation end-product receptor in bEnd.3 cells was detected by immunoblotting. RESULTS AND CONCLUSION: In the elevated plus maze test, the time spent in the open arms (P < 0.01) and the entries into open arms (P < 0.05) in the mice of model control group were evidently lower than those in the control group, whereas those were obviously increased in the model intervention group compared with the model control group (P < 0.05). Forced swimming test results showed that the immobile time exhibited a marked increase in the model control group compared with the control group (P < 0.05), but it was significantly decreased in the model intervention group compared with the model control group (P < 0.05). Hippocampal tissue mRNA sequencing showed that agomelatine enhanced the expression of low-density lipoprotein receptor-related protein 1 in the hippocampus of APP/PS1 mice. Western blot analysis revealed that the level of S416p-tau in HT22 cells was higher in the model group than the blank group (P < 0.05), while it was markedly decreased in the experimental group compared with the model group (P < 0.05); the level of S9p-GSK3β in HT22 cells was higher in the drug group than the blank group (P < 0.05) as well as higher in the experimental group than the model group (P < 0.05). Moreover, the expression of lowdensity lipoprotein receptor-related protein 1 in bEnd.3 cells was higher in the experimental group than the model group (P < 0.05). To conclude, agomelatine can alleviate anxiety- and depression-like behaviors in Alzheimer’s disease mice by promoting the clearance of β-amyloid and phosphorylated tau. [ABSTRACT FROM AUTHOR]

Objective To explore the effect of mindfulness-based stress reduction course on anxiety and depression status and perceived stress in patients undergoing surgery for thyroid cancer. Methods A total of 90 thyroid cancer surgery patients from March to November 2023 in the Thyroid Surgery Department of the First Affiliated Hospital of Zhengzhou University were divided into the intervention group and the control group, with 45 cases in each group. Before and after the intervention, the two groups were evaluated with the Perceived Stress Scale (CPSS), Anxiety Self-Assessment Scale (SAS) and Depression Self-Assessment Scale (SDS). Results After the intervention, the scores of CPSS,SAS and SDS in the intervention group were (34.534±6.452）, (44.243±3.684) and (42.854±3.215), which were significantly lower than those in the control group [ (39.824±5.243), (47.621±3.583), (45.964±3.265）].Conclusion The results indicate that MBSR course can effectively reduce the level of perceived stress, anxiety and depression in patients with thyroid cancer surgery. [ABSTRACT FROM AUTHOR]

Objective To investigate the impact of sedation nursing based on bispectral index (BIS) monitoring on the prognosis of patients with craniocerebral injury. Methods A total of 46 patients with craniocerebral injury admitted to this hospital between January 2018 and January 2019 were divided into two groups using a random number table. The control group (23 patients) received routine nursing intervention, while the study group (23 patients) received BIS-based sedation nursing intervention on the basis of the control group. The sedation effect, Glasgow Coma Scale (GCS) scores after intervention, and psychological status [Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale (SAS) scores were observed and compared between the two groups. Results The study group had a higher proportion of appropriate sedation and a better sedation effect, but the difference was not statistically significant compared with the control group (Z= 0.440,P=0.660). The GCS scores of the study group were lower than those of the control group after inter-vention, with a statistically significant difference (t=18.515, P<0.001). The SDS and SAS scores of the study group were lower than those of the control group after intervention, with statistically significant differences (t=7.770,9.539,P<0.001). Conclusion BIS-based sedation nursing can effectively improve the prognosis of patients with craniocerebral injury, reduce their negative emotions, and promote their recovery. [ABSTRACT FROM AUTHOR]

前庭系统是人体内一套精密且复杂的神经系统, 在维持人体平衡和空间定向方面发挥重要作用。前庭疾 病患者常出现焦虑、抑郁等情绪, 严重影响其临床诊疗效果和生活质量, 并导致病情反复, 从而形成恶性循环。前庭 疾病与情绪障碍共病的相关因素包括大脑神经解剖通路的重叠、认知功能障碍和自主神经功能紊乱等, 其中大脑神 经解剖通路的重叠中涉及到前庭神经核与调节情绪的相关核团, 如臂旁核、杏仁核、中缝背核、蓝斑核等, 这些神经 核团之间的相互投射及纤维联系奠定了前庭系统与情绪之间的解剖基础; 同时, 认知功能障碍与情绪障碍二者之间 存在交互作用, 导致前庭疾病伴发认知障碍的同时还逐渐扩展到情绪方面; 此外, 自主神经的调节是不受自主意识 控制的, 自主神经紊乱或许是前庭疾病与情绪障碍共病机制中关键的一环。 [ABSTRACT FROM AUTHOR]

Objective: To study the prevalence and association factors of depressive and anxiety disorders in the hypertensive population. Methods: Using the database obtained from the 2013 China Chronic Disease and Risk Factor Surveillance and the 2013-2015 China Mental Health Survey, 4 861 hypertensive residents were used as study subjects. And using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) as diagnostic criterion for depressive and anxiety disorders, the 12-month prevalence was calculated. Multifactorial lo- gistic regression models were used to explore the association factors of hypertension comorbid depressive and anxie-ty disorders. Results: The 12-month prevalence rates of depressive disorders and anxiety disorders were 4.1% and 5.0% in 4 861 hypertensive residents. Chinese Han [OR(95% CI): 2.00 (1.013.93)], lack of sleep [OR(95% CI): 1.82(1.34-2.48)], having myocardial infarction [OR(95% CI): 2.35 (1.18~4.67)] and stroke in the past year [OR(95% CI): 2. 10(1.19-3.72)], and chronic obstructive pulmonary disease [OR(95% CI): 2. 11(1. 11- 4.05)] were risk factors of hypertension comorbid depressive disorder. Hypertensive people with controlled blood pressure [OR(95% CI): 2. 01 (1.30-3.13)] had a higher risk of co-morbid depressive disorder than those with blood pressure above the normal range on this measurement. Chinese Han [OR (95% CI): 2.51 (1.324.80)], Southwest China [ OR(95% CI): 1. 64(1.022.63)], and lack of sleep [OR(95% CI): 1.45 (1.09-1.93)] were risk factors of hypertension comorbid anxiety disorder. Former but current non-smoking [OR(95% CI): 0.48(0.23 -0.99)] was a protective factor of hypertension comorbid anxiety disorder. Conclusion: The 12-month prevalence of anxiety disorder was higher than that of depressive disorder in this hypertensive population. Both Han and sleep deprived hypertensive people had a higher risk of comorbid depressive and anxiety disorders. [ABSTRACT FROM AUTHOR]

Objective Based on the "kidney brain bone" axis theory, this study aims to explore the common pathogenesis of postmenopausal osteoporosis (PMOP) and anxiety state, in order to provide new ideas for PMOP. Methods By searching relevant literature and research on the "kidney brain bone" axis theory, PMOP, and anxiety state in databases such as CNKI and PubMed, we aim to explore the correlation between the two in depth. Results The "kidney brain bone" axis integrates the relevant theories of "kidney, brain, and bone" in traditional Chinese medicine, summarizing the connections between the three. Hormones and neuropeptides are important neurotransmitters that connect the three, and can participate in the regulation of bone homeostasis and anxiety from multiple levels and dimensions. Conclusion The theory of the "kidney brain bone" axis reveals the common pathogenesis between PMOP and anxiety state, combining "kidney governing bone", "kidney storing consciousness", and neuropeptide regulation, providing new ideas for PMOP. [ABSTRACT FROM AUTHOR]

Globally, preoperative period anxiety is a common occurrence among adults undergoing elective surgery. Not only can preoperative anxiety lead to delays or cancellations of surgical procedures, but it can also negatively impact the prognosis of the condition being treated. To alleviate this issue, non-pharmacological interventions such as prayer, massage, music, imagery, and acupuncture have been widely employed. These methods have proven effective in reducing preoperative anxiety, lowering healthcare costs, and enhancing patient satisfaction. In particular, the traditional Chinese medicine technique of auricular acupressure offers a novel approach to managing preoperative anxiety through its ability to promote circulation, relieve pain, calm the mind, and induce tranquility. However, current research on auricular acupressure primarily focuses on postoperative scenarios, specific diseases, or types of surgery. Through literature review and analysis, this paper summarizes the application of auricular acupressure in alleviating preoperative anxiety among adults undergoing elective surgery and discusses its physiological mechanisms, providing a reference for clinical practice. Although auricular acupressure presents an effective non-pharmacological intervention, further research is needed to validate its efficacy in clinical settings, and attention must be paid to the risk of infection during its application. (全球范围内, 成年人在择期手术前普遍存在术前焦虑。术前焦虑不仅可能导致手术推迟或取消, 还可能影响疾病的预后。为了缓解这一情况, 非药物干预方法如祈祷、按摩、音乐、图像和针灸等被广泛应用, 这些方法能有效减轻术前焦虑, 降低医疗成本, 提高患者满意度。中医的耳穴压豆疗法, 通过行气活血止痛、宁心安神、镇静等效果, 为术前焦虑的管理提供了新的思路。然而, 目前关于耳穴压豆的研究主要集中在术后, 特定疾病或手术类型上。通过文献检索和分析, 本文总结了耳穴压豆在成年人择期手术中缓解术前焦虑的应用情况, 并探讨了潜在生理机制, 为临床实践提供了参考。尽管耳穴压豆为非药物干预提供了一种有效的手段, 但在临床应用中还需进一步地究验证其效果, 并注意操作中的感染风险。)

Objective To evaluate the effect of integrating fitness qigong into ERAS surgery to improve perioperative psychological health and sleep quality in patients with gastrointestinal cancer. Methods Based on the integration of martial arts and medicine, combined with the theory of fitness qigong and the concept of ERAS, the ERAS Baduancaoe was developed through clinical practice. A Total of 78 patients with gastrointestinal cancer admitted from March 2020 to June 2023 were selected as the research subjects. They were randomly divided into a control group of 39 cases and an experimental group of 39 cases using a random number table method. The control group received routine ERAS during the perioperative period, while the experimental group underwent the ERAS Baduancao on this basis. The anxiety status of patients was evaluated using the Self Rating Anxiety Scale (SAS), and sleep quality was observed using wearable smart monitoring devices and the Pittsburgh Sleep Quality Index(PSQI)scale. The perioperative anxiety status and sleep quality of the two groups of patients were compared. Results There were 9 patients lost to follow-up in the experimental group and 8 patients lost to follow-up in the control group. There was no statistically significant difference in SAS and PSQI scores between the two groups of patients before intervention (P>0. 05). The SAS score decreased in both two groups after intervention, and SAS score of patients in the experimental group were lower than that in the control group(P＜0. 05). The results of the two sleep monitoring methods for the two groups of patients were consistent. The overall PSQI score of patients in the experimental group was lower than that in the control group P＜0. 05). The sleep quality monitoring results by intelligent device indicated a superior sleep quality(P＜0. 05) and longer deep sleep duration(P＜0. 01) in the experimental group compared with those in the control group. There was no significant difference in the incidence of postoperative falls, anastomotic bleeding, and development of lower extremity deep vein thrombosis between two groups (P>0. 05). Conclusion The implementation of the baduancao exercise to accelerate recovery in patients with gastrointestinal cancer can relieve perioperative anxiety, improve sleep quality, and accelerate recovery, which is safe and feasible, and can be used clinically. (目的 评价健身气功融入加速康复外科改善胃肠癌患者围手术期负性情绪和睡眠质量的效果。方法 基于“武医融合”思想, 结合健身气功理论及加速康复外科理念, 通过江苏省中医院普外科临床护理实践, 形成加速康复八段操。选取2020年3月—6月收治的78例胃肠癌患者为研究对象, 随机数字表法分为对照组39例和试验组39例。对照组围手术期给予常规加速康复外科措施, 试验组在此基础上实施加速康复八段操。采用焦虑自评量表(SAS)评估患者焦虑状态, 穿戴式智能监测设备及匹兹堡睡眠质量指数(PSQI)量表观察睡眠质量, 比较两组患者围手术期焦虑状况及睡眠质量。结果 对照组脱落8例, 试验组脱落9例。最终对照组31例和试验组30例患者纳入统计。干预前, 两组患者SAS、PSQI量表评分差异无统计学意义(P＞0. 05)。干预后, 两组SAS评分较干预前下降, 且试验组SAS评分改善优于对照组, 试验组焦虑程度低于对照组(P＜0. 05)。两组患者PSQI量表和智能手表两种睡眠监测方式结果一致, 干预后试验组PSQI总评分低于对照组, 差异有统计学意义(P＜0. 05); 智能监测睡眠质量试验组优于对照组(P＜0. 05), 其中深睡眠时长试验组优于对照组(P＜0. 01)。术后跌倒、吻合口出血、下肢深静脉血栓等并发症发生率两组差异无统计学意义(P＞0. 05)。结论 胃肠癌患者实施加速康复八段操, 能改善围手术期焦虑状态, 提高睡眠质量, 加速患者康复, 且安全、可行, 值得临床借鉴推广。)

Objective To investigate the effect of auricular acupoint pressing combined with modified Wendan decoction in the treatment of essential hypertension and accompanying insomnia. Methods By adopting a convenient sampling method, totally 76 patients with primary hypertension and insomnia who were admitted to the Department of Traditional Chinese Medicine of Guangzhou Medical University Affiliated Hospital from January 2023 to August 2024 were included as research objects. These patients were randomly divided into two groups, with 38 patients in each group. In the control group, patients received conventional antihypertensive drug therapy and standard nursing care; In the observation group, in addition to receiving the same standard treatment as the control group, patients also received auricular acupoint pressing therapy and oral treatment with modified Wenpan decoction. The main objective of the study was to evaluate the changes in sleep quality (assessed using the Pittsburgh Sleep Quality Index), anxiety (assessed using the Hamilton Anxiety Scale), depression (assessed using the Hamilton Depression Scale), and blood pressure levels in the two groups before and after treatment. Results After treatment, the PSQI, HAMA, and HAMD scores in both groups were lower than those before treatment, and scores of observation group were significantly lower than those of the control group (P＜0. 05). After treatment, both groups had lower diastolic blood pressure and systolic blood pressure than those before treatment (P＜0. 05), and patients in the observation group had better outcomes in blood pressure reduction compared with those in the control group (P＜0. 05). Conclusion Auricular acupoint pressing combined with modified Wendan decoction is effective in lowering blood pressure, improving sleep quality and relieving anxiety and depression of patients with essential hypertension and accompanying insomnia. (目的 探讨耳穴压豆结合加味温胆汤口服治疗原发性高血压伴失眠症状患者的效果。方法 采用方便抽样的方法选取2023 年1月—2024年8月广州医科大学附属中医医院收治的76例原发性高血压伴失眠的患者为研究对象。采用随机数字表法将患者分为对照组和观察组, 各38例。对照组患者接受常规降压药物治疗和标准护理干预, 观察组在对照组基础上增加耳穴压豆联合加味温胆汤口服治疗。两组患者治疗观察周期均为10 d。采用匹兹堡睡眠质量指数(PSQI)评估患者睡眠质量, 采用汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评估患者负性情绪, 记录患者血压水平变化。结果 治疗后, 两组PSQI、HAMA和HAMD量表评分均较治疗前降低, 且观察组评分低于对照组, 差异有统计学意义(P＜0. 05)。治疗后, 两组收缩压、舒张压水平较治疗前降低, 且观察组血压水平改善幅度优于对照组, 差异有统计学意义(P＜0. 05)。结论 耳穴压豆联合加味温胆汤口服治疗方式在降低血压、改善睡眠以及减轻焦虑和抑郁情绪方面显示出良好的效果。)

This paper summarizes the nursing experience of a patient with essential hypertension and severe anxiety. By testing the twelve meridians of the patients through the Meridian-Collateral measuring instrument, the auricular acupoint pressing therapy by syndrome differentiation, in combination with daily life guidance, emotional care, psychological counseling and health education, were carried out to reduce blood pressure, relieve anxiety, and improve the quality of life of the patient. (本文总结经络仪检测联合耳穴压丸治疗1例原发性高血压合并重度焦虑患者的护理体会。患者入院后完善护理评估, 基于经络仪检测数据, 辨证取穴进行耳穴疗法, 同时加强生活起居护理, 指导患者饮食和运动, 并配合中医情志护理, 进而稳定控制患者的血压, 缓解其焦虑、眩晕症状。)

目的探讨艾司氯胺酮预处理对小儿隐匿阴茎矫治术后早期不良行为发生的影响。方法选择隐匿性阴茎矫治术患儿88例，手术时间小于1 h，年龄4～10岁，ASA分级I～Ⅱ级；采用数字表法随机分为艾司氯胺酮组（E组，n=44）和对照组（C组，n=44），E组麻醉诱导前20 min予以艾司氯胺酮0.5 mg/kg预处理，C组予以等量生理盐水静注，两组均采用喉罩静吸复合全身麻醉。在术前一天和入手术室时采用m-YPAS评估焦虑状态，记录诱导期ICC评分。分别记录诱导前（T0）、诱导后即刻（T1）、手术开始（T2）、入PACU（T3）、入PACU后10 min（T4）、出PACU前（T5）患儿的HR和MAP。记录苏醒期间PAED、FLACC评分。留取术前1天和术后第1天外周静脉血3 mL，检测MCP-1、Cortisol、Epinephrine水平。术后第3天、第7天对所有患儿行PHBQ问卷评分。结果E组术后第3天、第7天术后出现不良行为改变（NPOBCs）发生率明显低于C组（31.8% vs. 63.6%，P＜0.05； 18.2% vs. 40.9% ，P＜0.05）。E组术后第3天PHBQ中分离焦虑、睡眠焦虑、饮食障碍发生率明显低于C组，差异有统计学意义（P＜0.05）；两组整体焦虑、攻击性、冷漠退缩发生率相比较差异无统计学意义（P＞0.05）。术后第7天，2组PHBQ中各项指标发生率差异均无统计学差异（P＞0.05）。E组术后MCP-1明显降低，差异有统计学意义（P＜0.05）；而肾上腺素和皮质醇水平，2组比较差异无统计学意义（P＞0.05）。多因素Logistic回归分析发现艾司氯胺酮和入手术室的m-YPAS是患儿术后早期NPOBCs的影响因素，且二者作为预测NPOBCs发生的ROC曲线下面积AUC（95%CI）分别为0.659（0.544，0.774）和0.918（0.849，0.988），敏感性分别为66.70%和92.90%，特异性分别为65.20%和84.80%，差异有统计学意义（P＜0.05）。两组PACU中PAED评分和FLACC评分差异无统计学意义（P＞0.05）。结论艾司氯胺酮预处理可以降低接受隐匿性阴茎矫治术儿童的术后早期NPOBCs的发生，且可能与降低术后MCP-1有关，同时不增加围术期不良事件，安全性较高。

Objective To investigate the influence of Traditional Chinese Medicine (TCM) emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease. Methods Totally 90 patients undergoing hemodialysis for end-stage renal disease were randomly divided into the observation group and control group, with 45 cases in each group. All patients received routine nursing interventions during hemodialysis, and patients in the observation group were given Traditional Chinese Medicine emotion regulation. The Self-rating Anxiety Scale and Self-rating Depression Scale were used to evaluate the psychological status, and Kidney Disease Quality of Life - Short Form (KDQOL-SFTM), Version 1. 3 was used to evaluate quality of life of patients. Results Patients in the observation group achieved better outcome of SAS and SDS compared with those in the control group (P＜0. 05). Scores of Kidney Disease Quality of Life(KDTA) were increased in both two groups after intervention, and subscales scores of KDTA in the observation group were higher than those in the control group except for subscale of Working Status. Score of Short Form 36(SF-36) was increased in both two groups after intervention, and score of SF-36 in the observation group was higher than that in the control group(P＜0. 05). Conclusion Traditional Chinese Medicine emotion regulation is effective to relieve the negative emotions and improve the quality of life of patients undergoing hemodialysis for end-stage renal disease. (目的 探讨中医情志护理对肾病透析患者心理及生活质量的影响。方法 将90例肾病透析患者随机分为观察组和对照组, 各45例。对照组采用血液透析常规护理, 观察组在对照组基础上实施中医情志护理干预。采用焦虑自测量表(SAS)和抑郁自测量表(SDS)进评估患者心理状态, 采用肾脏疾病生活质量简表 (KDQOL-SFTM1. 3)评估患者生活质量。结果 观察组焦虑、抑郁状况改善优于对照组, 差异有统计学意义(P＜0. 05)。干预后, 两组肾病相关生存质量(KDTA)各维度评分均升高, 除工作状态(WS)维度, 观察组均高于对照组, 差异有统计学意义(P＜0. 05)。干预后, 两组一般健康相关生存质量(SF-36)量表各维度评分均升高, 且观察组评分高于对照组, 差异有统计学意义(P＜0. 05)。结论 肾病透析患者采用中医情志护理, 有助于改善焦虑、抑郁情绪, 提高其生活质量。)

ABSTRACT Drawing from rational emotive behavior therapy (REBT), this research explored the predictive power of critical thinking (CT) disposition on foreign language (FL) engagement. Additionally, it examined whether emotions mediate this relationship and how achievement levels moderate these mediation effects. The study involved 3238 Chinese secondary students, with data collected through self‐reported scales measuring CT disposition, enjoyment, anxiety, boredom, and engagement in FL learning, as well as FL achievement tests. Mediation analysis revealed that CT disposition was significantly and positively associated with FL engagement. Moreover, this relationship was mediated by FL enjoyment, anxiety, and boredom. Additionally, anxiety and boredom notably mediated the relationship between CT disposition and FL engagement, especially among high‐achieving students. However, moderated mediation analysis showed that the mediation effect of FL enjoyment did not significantly differ between high‐achieving and low‐achieving groups. This research holds theoretical, practical, and methodological implications for FL teaching and learning, providing insights into how emotional responses influenced by CT can affect student engagement across different achievement levels. [ABSTRACT FROM AUTHOR]

Objective: To explore the effects of mindfulness-based stress reduction (MBSR) on pain relief, anxiety and depression and quality of life in naval personnel with chronic pain. Methods: A total of 72 naval personnel with chronic pain were randomly divided into MBSR group and routine intervention group. The routine intervention group received routine care, while the MBSR group received MBSR in addition to routine care. The Short-Form McGill Pain Questionnaire (SF-MPQ), Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and 36-item Short Form Health Survey Scale (SF-36) were used at baseline and after 8 weeks of intervention. Results: The differences in the scores of 3 subjects of SF-MPQ, SAS, SDS and SF-36 in MBSR group at baseline and 8 weeks after intervention were higher than those in routine intervention group (Ps <0.05). Conclusion: It suggests that mindfulnecs-based stress reduction could alleviate the degree of pain, anxiety and depression of patients with chronic pain in naval personnel and improve their quality of life. [ABSTRACT FROM AUTHOR]

Copyright of China Journal of Oral & Maxillofacial Surgery is the property of Shanghai Jiao Tong University, College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Guangdong Pharmaceutical University is the property of Journal of Guangdong Pharmaceutical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science & Technology of Cereals, Oils & Foods is the property of Science & Technology of Cereals, Oils & Foods Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effects of dural puncture epidural (DPE) blockade on the anxiety and labor analgesia of primiparous women during natural childbirth. Methods A retrospective analysis was conducted on 180 primiparous women who received intrathecal labor analgesia at Jinjiang Hospital of Traditional Chinese Medicine from January 2023 to January 2024. They were divided into two groups according to the method of labor analgesia: the DPE group and the epidural blockade group (EP group), with 90 cases in each group. The time to achieve a visual analogue scale (VAS) score 1, total ropivacaine dosage, VAS score at full cervical dilation, and the incidence of sacrococcygeal blockade failure were recorded. Scores on the self-rating anxiety scale (SAS) before and after childbirth were documented, along with the occurrence of adverse reactions in parturients. Results The DPE group showed a shorter time to reach a VAS score 1, used less total ropivacaine, had lower VAS scores at full dilation, and had a lower incidence of sacrococcygeal blockade failure compared to the EP group, with postpartum SAS scores also being lower (all P<0.05). There was no significant difference in the rate of adverse reactions between the two groups (P>0.05). Conclusion For primiparous women undergoing natural childbirth, DPE blockade provides more effective labor analgesia and re- duces maternal anxiety. [ABSTRACT FROM AUTHOR]

Objective To understand the current situation of the mental health of medical students in a university, to explore in depth the influencing factors of the mental health of medical students, and to provide clues and reference bases for the mental health counseling and education of medical students. Methods A web-based questionnaire survey was conducted on 1 767 medical students enrolled in a university school in Xinjiang using a general condition questionnaire and an emotional self-assessment scale, and combined with one-way and logistic regression analyses to explore the mental health status of medical students and their influencing factors. Results The incidence rates of stress, anxiety and depression were 17.0% (300/1 767), 37.6% (665/1 767) and 29.4% (520/1767) respectively. Univariate analysis found statistically significant differences between different grades, ethnicity, family economic status, physical activity, appetite status, sleep status, and getting along with classmates or friends (P<0.05). Logistic regression analysis revealed that family economic status, physical exercise, sleep status, and getting along with classmates or friends were the main influencing factors for the occurrence of psychological problems among students in a medical school in Xin- jiang (P<0.05). The partial correlation results found a positive correlation (P<0.05) between the two of stress, anxiety and depression, with the largest correlation coefficient (0.57) between the stress and anxiety scores. Conclusion Medical students in a university in Xinjiang are experiencing different degrees of psycho- logical problems of stress, anxiety and depression. It is important to strengthen the psychological monitoring of poor medical students, pay close attention to students with poor sleep quality, and guide them to have a regular work and rest schedule and to maintain a moderate level of exercise. [ABSTRACT FROM AUTHOR]

Objective To explore the relationship between social media addiction and anxiety among college students and the role of bedtime procrastination and stress perception. Methods A total of 15493 college students were selected by convenience sampling in September 2023 with using the Bergen Social Networking Addiction Scale, the Bedtime Procrastination Scale, the Chinese Perceived Stress Scales and the Generalized Anxiety Disorder 7-item Scale. SPSS25.0 macro program PROCESS was used to analyze the mediating effect of bedtime procrastination and the moderating effect of stress perception. Results The social media addiction was positively predicted college students' anxiety (β=0.307, P＜0.001). Bedtime procrastination partially mediated the relationship between social media addiction and anxiety in the college students. The mediation effect value was 0.060 (95% Bootstrap CI=［0.055-0.065］), the mediating effect accounted for 19.54% of the total. Stress perception moderated the relationship between bedtime procrastination and anxiety (β=0.094, P＜0.001). As the level of perceived stress increased, the positive association between bedtime procrastination and anxiety became stronger. Conclusion Social media addiction can directly affect anxiety in the college students, or indirectly affect it through bedtime procrastination, and perceived stress moderates the path from bedtime procrastination to anxiety in the mediation model. [ABSTRACT FROM AUTHOR]

Objective: Evaluate the effects of brief mindfulness meditation training on improving negative emotions, mindfulness attention awareness, and sleep quality in patients after percutaneous coronary intervention (PCI) for coronary heart disease. Methods: Eighty-four patients with coronary heart disease after PCI admitted to the cardiology department were selected. According to the principle of simple randomization, they were divided into an intervention group of 42 cases and a control group of 42 cases. The Self Rating Anxiety Scale/Self Rating Depression Scale, Mindfulness Attention Awareness Scale, and Pittsburgh Sleep Quality Index Scale were used as evaluation indicators before and after intervention. Results: The difference in total scores of anxiety, depression, and mindfulness attention awareness before and after intervention in the intervention group was higher than that in the control group (P<0.05). The difference in total sleep score, sleep quality, time to fall asleep, sleep duration, use of hypnotic drugs, daytime dysfunction, and total sleep score before and after intervention was higher than that of the control group (P<0.05). Conclusion: It suggests that brief mindfulness meditation training could alleviate negative emotions in patients with coronary heart disease after PCI, improve mindfulness awareness, and improve sleep quality. [ABSTRACT FROM AUTHOR]

To explore the mediating effect of sleep duration on the relationship between qi stagnation constitution and anxiety/depression in junior high school students. Methods From March 20 to March 31, 2020, a total of 10, 325 students from 6 junior high schools in Henan, Liaoning, Shaanxi, Shandong, and Fujian provinces were sampled by cluster sampling. Firstly, the general conditions ( age, gender, grade, hometown, whether they are an only child) and sleep duration were collected, and their qi stagnation constitution, depression and anxiety status were evaluated by using the Qi Stagnation Subscale in the "' TCM Constitution Classification and Judgment Scale", the Patient Health Questionnaire (PHQ-9) and the Generalized Anxiety Disorder ( GAD-7). Secondly, Spearman correlation analysis was used to explore the correlation between qi stagnation constitution, sleep duration, and anxiety/ depression. Then, linear regression analysis and mediating effect test were used to explore the relationship between qi stagnation constitution and anxiety/depression in junior high school students, and the mediating effect of sleep duration was analyzed, and the results were verified. Results (i) The detection rate of anxiety in non-only children was higher than that of only children (X1 = 11. 198, P = 0. 001) ； The detection rate of anxiety (f = 106. 967, P<0. 001) or depression (f = 84. 692, P<0. 001) was higher among senior students than those in lower grades, while those of girls with anxiety = 100.441, P<0.001) or depression (太2 = 71.418, P <0.001) were higher than those of boys. The detection rates of anxiety (太2 = 1 092. 298, P<0. 001) and depression (X1 = 866. 740, P<0. 001) in qi stagnation constitution students were higher than those of non-qi stagnation constitution students, and the detection rates of anxiety (χ2 = 1 076. 716, P<0. 001) and depression (太2 = 1 099. 725, P<0. 001) in students whose sleep duration less than 8 h were higher than those of whose sleep duration more than 8 h, and the shorter the sleep duration, the higher the detection rate. (ii) Qi stagnation constitution positively predicted anxiety/depression (β = 0.679, P<0.001;β = 0.718, P<0.001), and sleep duration had a negative predictive effect on anxiety/depression (β = -0.403, P<0. 001 ；β = -0. 439, P<0.001). ( iii) Sleep duration played a partial mediating role in the relationship between qi stagnation constitution and anxiety/depression in junior high school students, and the mediating effect accounted for 13. 40% and 13. 79% of the total effect, respectively. Conclusion Although qi stagnation constitution mainly affects anxiety/depression through direct effect, it can still be partially indirectly realized through the mediating variable of sleep duration, that is, the shorter the sleep duration, the higher the risk of anxiety/depression in junior high school students. Therefore, the mental health problems of junior high school students can be prevented and improved by regulating qi stagnation constitution and ensuring adequate sleep duration. [ABSTRACT FROM AUTHOR]

Objective To investigate the impact of diverse health education on patients' quality of life and anxiety after periodontally accelerated osteogenic orthodontics ( PAOO) surgery, providing clinical evidence for exploring better health education models. Methods Patients who visited the Orthodontics Department of Kunming Medical University's Affiliated Stomatology Hospital and required PAOO surgery from April 2022 to December 2023 were selected for this study. They were randomly assigned into a control group and an experimental group, each consisting of 42 patients. The control group received standard health education, which included preoperative verbal guidance, intraoperative communication, and postoperative instructions. In contrast, the experimental group, in addition to the regular health education, had a diversified health education group established, providing one-onone guidance during the perisurgical period. Anxiety ( SAS, MDAS), pain ( VAS), postoperative clinical manifestations (such as bleeding, nausea, sleep issues, etc.), self-management efficacy for oral health (SESS), and dental plaque index (PLI) were assessed and compared between the two groups before and after surgery. Before and after the PAOO surgery, comparisons were also made regarding anxiety, fear, pain, quality of life, and selfmanagement abilities for oral health between the two groups. Results The patients in the observation group had significantly lower SAS scores three days post-surgery compared to the control group, with MDAS scores also showing a significant decrease ( P < 0.001) . Seven days post-surgery, the VAS scores indicated a significant reduction in the observation group compared to the control group (P < 0.001). The level of post-operative bleeding and nausea in the observation group was significantly lower than in the control group (P < 0.001). Additionally, the self-efficacy regarding oral health in the observation group significantly improved one month after surgery ( P < 0.001), with a notable reduction in the plaque index (P < 0.05). In terms of quality of life, the overall quality of life scores for the observation group were significantly higher than those for the control group one month after surgery (P < 0.001). Conclusion In the perioperative care of PAOO, incorporating diverse health education measures can effectively reduce patient discomfort, alleviate anxiety, and improve patients' quality of life during the perioperative period as well as their ability to manage oral health independently. [ABSTRACT FROM AUTHOR]

Objective To study the psychological state and self-management skills of peritoneal dialysis patients and to examine the factors influencing them and their interrelationships. Methods A convenience sampling method was used, and general information surveys, the Hospital Anxiety and Depression Scale (HADS), the SelfEsteem Scale, and the Self-Management Scale were employed to conduct a questionnaire survey of 158 patients undergoing peritoneal dialysis. Results The HADS score of peritoneal dialysis patients was (7.46±4.14), which was higher than the norm; the self-esteem level score was (26.40±5.17), which was lower than the norm (P < 0.05) ; and the self-management ability score was (62.60±9.22), which was at an average level (P < 0.05). Factors such as education level, average monthly income, type of health insurance, and the psychological state of patients had a certain effect on the self-management ability of peritoneal dialysis patients (all P < 0.05). Conclusion There is a correlation between the psychological state of peritoneal dialysis patients and their self-management skills. Targeted interventions to reduce anxiety and depression in patients, while enhancing their self-esteem and self-management abilities, are fundamental to clinical care. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Acupuncture & Tuina Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Acupuncture & Tuina Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the application effect of narrative nursing in pediatric preputial dilation and separation. Methods A total of 240 children aged 5-12 years who underwent preputial dilation and separation in the outpatient department of a tertiary children′s hospital from July to August 2023 were selected. Among them, 120 patients admitted in July 2023 were assigned to the control group, and 120 patients admitted in August 2023 were assigned to the experimental group. The control group received routine nursing, while the experimental group received narrative nursing in addition to routine nursing. The anxiety level, postoperative pain level, and complication rate were compared between the two groups. Results The anxiety score [ (30.16±6.7) points], postoperative pain score [2.0 (2.0, 4.0) points], and complication rate (12.5%) in the experimental group were significantly lower than those in the control group [ (32. 48±8. 84) points, 8. 0 (5.0, 12.0) points, and 30.0%, respectively], with statistically significant differences (P＜0.05). Conclusion The application of narrative nursing in pediatric preputial dilation and separation can alleviate anxiety and pain of children, reduce the complication rate, improve surgical experience, and increase the success rate of surgery, which is worthy of clinical promotion and application. [ABSTRACT FROM AUTHOR]

Objective To understand the detection rates of anxiety and depression during pregnancy and their influencing factors. Methods A cross-sectional survey was conducted from July 2022 to July 2023 at the Hunan Provincial Maternal and Child Health Care Hospital. The general data of pregnant women and their levels of anxiety and depression during pregnancy were assessed using a basic information questionnaire, a self-rated anxiety scale, and the Edinburgh Postnatal Depression Scale. A multivariable logistic regression model was used to analyze the influencing factors of anxiety and depression during pregnancy. A total of 924 questionnaires were distributed, with 892 valid responses, yielding an effective response rate of 96.5%. Results Among the 892 pregnant women surveyed, the detection rate for anxiety was 16. 8% (150/892), and the detection rate for depression was 51. 3% (458/892). History of spontaneous miscarriage and pregnancy with malformed fetuses were positively correlated with prenatal anxiety [odds ratio (OR) =1. 660, 4.125, 95% confidence interval (95%CI) 1.005-2. 742 and 1.140-14. 930, respectively]. Ethnic minorities were positively correlated with prenatal depression (OR=1. 931, 95%CI 1.068-3. 493). No insomnia after the last month of pregnancy and the three months before pregnancy, and good or very good marital relationships were negatively correlated with prenatal depression (OR=0. 425, 0. 344, 0. 325, 0. 245, respectively; 95% CI 0. 233-0. 773, 0. 165-0. 718, 0. 112-0. 944, 0.086-0. 700). Conclusion Special attention should be paid to the mental health of pregnant women with a history of natural miscarriages, pregnancies with malformed fetuses, and those from ethnic minorities. Absence of insomnia and good marital relationships are protective factors against depression during pregnancy. [ABSTRACT FROM AUTHOR]

Objective To explore the effects of mindfulness intervention on alleviating anxiety and depression, and improving sleep quality in cervical cancer patients during concurrent chemoradiotherapy. Methods From June 2021 to April 2022, a total of 94 cervical cancer patients treated in the Department of Abdominal Oncology of this hospital were randomly divided into an experimental group and a control group, with 46 in the experimental group and 48 in the control group. Both groups received standard care, with the experimental group additionally undergoing an 8-week mindfulness intervention. The Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and Pittsburgh Sleep Quality Index (PSQI) were used to assess anxiety, depression, and sleep quality before and after the intervention in both groups. Results After the intervention, scores of SAS, SDS, and PSQI in both groups were lower than before the intervention. Furthermore, the scores in the experimental group were significantly lower than those in the control group, with statistically significant differences (P＜0. 05). Conclusion Mindfulness intervention effectively relieves anxiety and depression in cervical cancer patients during concurrent chemoradiotherapy and improves their sleep quality. [ABSTRACT FROM AUTHOR]

Objective: To explore the relation of depressive and anxiety symptoms to defense mechanism in transgender population. Methods: Totally 451 transgender patients in the sexual and psychological outpatient department of a hospital were selected. They were assessed with the self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS) and Defense Mechanism Scale (DSQ). The SDS standard score of 53 was classified as having depressive symptoms, and the SAS standard score of ≥50 was classified as having anxiety symptoms. Results: The detection rates of depression and anxiety were 46.8% and 28.8% respectively. Multiple linear regression analysis showed that SDS scores were positively correlated with DSQ scores of projection, conceit, complaint, withdrawal, somatization, control, isolation and identity (β= 0.08-0.22), while SDS scores were negatively correlated with DSQ scores of sublimation, depression, omnipotence with incompetence and denial (β = 0.090.19) The SAS scores were positively correlated with the DSQ scores of projection, latent manifestation, somatization, control, isolation, identity, and consumption tendency (B=0.09-0.26), while the SAS scores were negatively correlated with the DSQ scores of sublimation, depression, omnipotence accompanied by incompetence, and denial (β -0.090.15). Conclusion: The proportion of depression and anxiety symptoms detected in the transgender group is higher, which may be related to the use of some defenses. [ABSTRACT FROM AUTHOR]

Background Self-perceived burden, anxiety and depression are among the most important factors affecting quality of life. At present, there is a lack of understanding on the research status and influencing factors of self-perceived burden in liver transplant recipients. Previous studies have shown that self-perceived burden, anxiety, depression and quality of life are correlated in pairs, but the effecting path among the three are not yet clear. Objective To explore the correlation of self-perceived burden and anxiety/depression with quality of life in liver transplant recipients, so as to provide guidance for psychological nursing intervention in clinical patients. Methods A total of 200 patients liver transplant recipients were enrolled from the liver transplantation inpatient and outpatient clinics of Jiangsu Province Hospital and Qinhuai Medical Area, General Hosptial of Eastern Theater Command of People's Liberation Army of China from March 2022 to February 2023. Patients were evaluated using Self- perceived Burden Scale (SPBS), Hospital Anxiety and Depression Scale (HADS) and the Chinese version of Post Liver Transplant Quality of Life Questionnaire (pLTQ). Spearman correlation analysis was used to examine the correlation among the scales. A structural equation model using Mplus 8. 3 was utilized to testify the relationship among self-perceived burden, anxiety/depression and quality of life in liver transplant recipients. Bootstrap method was used to test the effecting pathway. Results There were statistically significant differences in SPBS scores of liver transplant recipients with different levels of education and fannual family income (H=9. 656, 18. 796, P< 0. 05). There were statistically significant differences in HADS scores of liver transplant recipients with different numbers of somatic symptoms (H=9. 859, P<0. 05). There were statistically significant differences in the Chinese version of pLTQ scores of liver transplant recipients with different levels of education, postoperative survival time and numbers of somatic symptoms (H= 6. 892, 8. 023, 16. 099, P<0. 05). The total and each dimension scores in SPBS of liver transplant recipients were positively correlated with the total score and anxiety/depression dimension scores in HADS (r=0. 464~0. 586, 0. 460~0. 593, 0. 286~ 0. 408, 0. 464~0. 583, P<0. 01) and negatively correlated with the total score and each dimension scores in the Chinese version of pLTQ (r=-0. 572~-0. 416, -0. 599~-0. 441, -0. 365~-0. 213, -0. 559~-0. 428, P<0. 01). Structural equation model denoted that self-perceived burden negatively affected quality of life (β =-0. 186, P<0. 01). Anxiety/depression also negatively affected quality of life (β =-0. 679, P<0. 01). The self-perceived burden indirectly affected the quality of life of liver transplant recipients through anxiety and depression, with an effect value of -0. 429, accounting for 69. 76% of the total effect. Conclusion The quality of life in liver transplant recipients may be related to their self-perceived burden and anxiety/depression. Self-perceived burden may affect the quality of life of liver transplant patients through anxiety and depression. [ABSTRACT FROM AUTHOR]

Background The mental health problems of employees in administrative organs and public institutions are highly valued. However, there is a lack of understanding regarding the mental health status of employees in provincial and municipal administrative organs and public institutions in Qinghai region. Objective To analyze the anxiety and depression of employees in provincial and municipal administrative organs and public institutions in Qinghai region, so as to provide references for promoting their mental health and intervening in psychological problems. Methods From October 23 to 28, 2022, a total of 3 096 employees in provincial and municipal administrative organs and public institutions in Qinghai region were enrolled using stratified cluster sampling technique, and were assessed using Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Results A total of 1797 (58. 04%) employees in municipal and above administrative organs and public institutions in Qinghai region completed a valid questionnaire survey. Depressive symptoms were noted in 579 (32. 22%). SDS scores yielded statistical difference among the selected employees of different ethnicities, types of job positions and educational levels (F=9. 074, 101. 488, 4. 477, P<0. 01), and the severity of depressive symptoms also demonstrated statistical difference among the selected employees with different ethnicities, educational levels and types of job positions (H=49. 196, 17. 028, 160. 848, P<0. 01). Anxiety symptoms were detected in 711 (39. 57%) employees. SAS scores exhibited statistical difference among the employees with different genders, ages, ethnicities, educational levels, marital status and types of job positions (t=-4. 571, F=6. 648, 3. 950, 5. 243, 12. 008, 22. 253, P<0. 01). Statistical differences were also illustrated in the severity of anxiety symptoms among the selected employees with different ages, genders, ethnicities, educational levels, marital status and types of job positions (H=24. 361, -3. 788, 28. 365, 24. 268, 25. 976, 56. 204, P<0. 01). Conclusion About one-third of employees in municipal and above administrative organs and public institutions in Qinghai region may have symptoms of depression and anxiety. The depression symptoms are more severe among Tibetan people, those with low education levels and ordinary civil servants. The anxiety symptoms are more severe among employees aged 30 and below, those with low education levels, unmarried and those in technical positions. [ABSTRACT FROM AUTHOR]

Objective To investigate the prevalence of anxiety and depression in patients with Hepatitis C (HCV) and its influencing factors, to provide basis for improving the mental health of this population. Methods From July to September 2022, a questionnaire survey on anxiety and depression was conducted among 486 HCV patients in Wenshan Prefecture of Yunnan Province and Xuzhou city of Jiangsu Province with the use of a comprehensive hospital anxiety/depression scale. The differences in the prevalence of anxiety and depression among HCV patients with different characteristics were analyzed using the Chi-square test, and a multivariate logistic regression model was used to analyze the influencing factors of anxiety and depression in HCV patients. Results A total of 483 valid questionnaires were collected, with an effective response rate of 99.38% (483/486). The detection rate of anxiety symptoms was 22.15% (107/483), and the detection rate of depression symptoms was 31.88% (154/483). The results of the multivariate logistic regression analysis indicated that females (OR=1.906, 95%CI: 1.165-3.120), patients with other diseases (OR=2.957, 95%CI: 1.828-4.783), and those experiencing liver discomfort (OR=3.360, 95%CI: 1.428-3.867) had a higher risk of anxiety. Compared to farmers or migrant workers, those who were unemployed or seeking employment (OR=2.246, 95%CI: 1.264-3.992) had a higher risk of anxiety. Individuals with per capita household monthly income less than 1 000 yuan (OR=8.463, 95%CI: 2.432-29.452) or between 1 000 and 3 000 yuan (OR=6.592, 95%CI: 1.899-22.882) had a higher risk of anxiety compared to those with an income greater than 3 000 yuan. For depression, individuals aged 50 years or older (OR=1.972, 95%CI: 1.262-3.080), those with other diseases (OR=1.647, 95%CI: 1.082-2.507), and those experiencing liver discomfort (OR=1.937, 95%CI: 1.220-3.074) had a higher risk. Individuals with a household per capita monthly income less than 1 000 yuan (OR=6.971, 95%CI: 3.011-16.139) or between 1 000 and 3 000 yuan (OR=3.773, 95%CI: 1.607-8.857) had a higher risk of depression compared to those with an income greater than 3 000 yuan. Conclusion The prevalence of anxiety and depression among HCV patients is relatively high and is associated with gender, age, occupation, low per capita household monthly income, comorbidities, and the presence of liver discomfort. Appropriate measures should be taken to reduce the occurrence of anxiety and depression in HCV patients to improve their mental health. [ABSTRACT FROM AUTHOR]

Objective To explore the mediating role of eating disorders in the relationship between body image satisfaction and anxiety symptoms among college students, and further examine the moderating effect of mindfulness on this mediating pathway. Methods By using convenience sampling, we conducted baseline and follow-up surveys among freshmen and sophomores at two universities in Xizang Autonomous Region from September to December 2021. Measurements included the Generalized Anxiety Disorder Scale, the body image satisfaction subscale of the Multidimensional Body-Self Relations Questionnaire, the Eating Attitudes Test, and the Mindful Attention Awareness Scale. Data analyses performed using SPSS 23.0 included Pearson correlation analysis, mediation (model 4), and moderation (model 58) effect analysis. Results A total of 2 993 students participated in both the baseline and follow-up surveys, including 1 007 males (34.3%) and 1,666 Tibetan and other ethnic minorities (56.8%), with an average age of 19.8 (SD=1.3) years. Body image satisfaction significantly predicted anxiety symptoms, and this relationship was partially mediated by disordered eating. The presence of mindfulness moderated the impact of body image satisfaction on disordered eating and the influence of disordered eating on anxiety symptoms, indicating varying strengths of these relationships at different levels of mindfulness. Conclusion This study demonstrates that body image satisfaction can significantly predict anxiety symptoms, with disordered eating playing a mediating role in this relationship. The moderating effect of mindfulness further reveals that students with high levels of mindfulness are less likely to experience eating disorders influenced by body image dissatisfaction. Interventions for college students' mental health should consider including management of body image and eating behaviors, as well as mindfulness training. [ABSTRACT FROM AUTHOR]

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cancer-related pain, is one of the most common and troublesome symptoms affecting quality of life and mental health of patients with cancer. Psychotherapy is a treatment intervention used to help individuals manage and overcome a range of emotional, psychological, and behavioral issues. This paper reviewed studies on psychological nursing of patients with cancer pain in perspectives of pain awareness, factors influencing the emotional disorders and related psychological nursing interventions, in order to provide reference for pain relief and improvement of mental health and quality of life. (癌痛是癌症患者的常见症状, 不仅影响患者生活质量, 同时也会给给患者带来巨大的心理负担。心理疗法主要针对癌痛患者的情感、认知和行为等方面的问题。本研究就疼痛的认识、癌痛情志障碍影响因素以及相关心理护理措施进行综述, 旨在为改善癌痛患者心理状态、减轻疼痛和提高生活质量提供参考。)

目的　观察艾司氯胺酮复合静脉全身麻醉在乳腺癌切除术中的麻醉效果。方法 88例择期行乳腺癌切 除术的乳腺癌患者随机分为观察组和对照组各44例，观察组采用艾司氯胺酮复合静脉全身麻醉，对照组采用静脉 全身麻醉，视觉模拟疼痛评分表 (VAS)评估不同时点 (术后第 1 天、第 2 天)患者疼痛情况，医院焦虑—抑郁量表 (HADS)评价不同时点 (术前 1 天及术后第 1 天、第 2 天、第 5 天)患者焦虑、抑郁情绪，理查兹—坎贝尔睡眠量表 (RCSQ)评估不同时点 (术前1天及术后第1天、第2天、第5天)患者睡眠质量，并记录手术时间、麻醉维持用量及不 良反应。结果　与同组术后第1天比较，两组术后第2天VAS评分减少 (P均<0. 05)；与对照组比较，观察组术后第2 天VAS评分减少 (P均<0. 05)。与同组术前1天比较，观察组术后第1天和第2天RCSQ总评分减少、HADS-A评分增 加、HADS-D评分增加，术后第5天HADS-A评分减少 (P均<0. 05)；与同组术前1天比较，对照组术后第1天RCSQ总 评分减少、HADS-D评分和HADS-A评分增加，术后第2天RCSQ总评分和HADS-A评分减少、HADS-D评分增加，第5 天 HADS-A 评分和 HADS-D 评分减少 (P均<0. 05)；与对照组比较，观察组患者术后第 1、2天 RCSQ 评分增加 (P均< 0. 05)，术后第1天HADS-A、HADS-D评分减少 (P均<0. 05)。两组手术时间、丙泊酚维持量、瑞芬太尼维持量、不良 反应比较，P 均>0. 05。结论　艾司氯胺酮复合静脉全身麻醉在乳腺癌切除术中的应用效果较好，可减轻术后疼痛 和焦虑、抑郁情况，改善乳腺癌患者术后睡眠质量，且不增加麻醉风险。 [ABSTRACT FROM AUTHOR]

Objective: To explore the effects of internet-based group cognitive-behavioral therapy (IGCBT) on the depressive and anxiety symptoms in patients with major depressive disorder (MDD). Methods: Eighty pa- tients with MDD were recruited and randomly divided into IGCBT combined drug therapy group and control group with drug therapy. Blind assessments were performed using the Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) three times at baseline, 4 weeks after treatment and 8 weeks after treatment, respectively. Results: The effective rates of HAMD and HAMA at the end of the 4th and 8th week, and the effective rates of HAMA at the end of the 8th week were higher in the combined treatment group than those in the control group (Ps <0.05). The total scores of HAMD and HAMA in the combined treatment group and the control group were lower at the end of the 4th and 8th week than those at baseline (Ps <0.001). The total scores of HAMD and HAMA were lower in the combined treatment group than those in the control group at the baseline, 4 weeks and 8 weeks after treatment (Ps <0.01). Conclusion: It suggests that internet-based group cognitive-behavioral therapy combined with antidepressant medication has a better effect on relieving depressive and anxiety symptoms in patients with ma- jor depressive disorder than drug therapy alone, and especially has a better effect on improving anxiety symptom. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of West China Journal of Stomatology is the property of Sichuan University, West China College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the effect of cognitive behavioral intervention instead of conventional nursing on anxiety and depression in patients with functional fecal incontinence. Methods A total of 40 раtients with functional fecal incontinence in the hospital from June 2021 to June 2022 were divided into the control group and the observation group according to the random number method, with 20 cases in each group. Both groups were given routine treatment (pelvic floor muscle training+trigger electrical stimulation training), while the patients in the control group were given routine nursing, while the patients in the observation group were given cognitive behavioral intervention, and the observation was carried out for four weeks. The clinical efficacy, Wexner Cleveland anal incontinence scale, self-rating anxiety scale and self-rating depression scale were compared between the two groups before and after intervention. Results The total effective rate of the observation group [90.0% (18/20)] was higher than that of the control group [75.0%(15/20)], with statistical significance (X=3.491,P<0.05). After the intervention, the scores of Wexner Cleveland anal incontinence scale self-rating anxiety scale and self-rating depression scale in the observation group and the control group were all lower than those before the intervention and the observation group was lower than the control group and the differences were statistically significant (P<0,05). Conclusion Through cognitive behavior intervention, the anxiety and depression of patients with fecal incontinence can be significantly alleviated, thus enhancing the therapeutic effect and having a positive impact on the recovery of patients. [ABSTRACT FROM AUTHOR]

Objective To investigate the depression status and its influencing factors of children and adolescents in a psychiatric hospital in Xiamen, and to provide ideas and methods to improve the mental health status of children and adolescents. Methods A retrospective study was conducted on 2 400 children and adolescents who visited Xiamen Xianyue Hospital from July 2019 to September 2023. Children and adolescents were required to complete the screen for child depression related emotional disorders, social anxiety scale for children, the screen for child anxiety related emotional disorders and symptom checklist 90 at the psychological assessment room of the hospital, Results The detection rate of depression among children and adolescents was 85.33%(2 048/2 400). The proportion of girls with depressive symptoms was higher than that of boys, and the proportion of middle or high school students with depressive symptoms was higher than that of primary school students, with statistically significant differences(P<0.05). Anxiety symptoms [odds ratio (OR) = 3.597,95% confidence interval [95% (CI) 2.548-5.078], social anxiety symptoms (OR=2.819, 95% CI 1.995-3.982), obsessive symptoms (OR=1.643,95% CI 1.083-2.494), hostility (OR=1.670,95% CI 147-2.431),and issues with eating and sleeping (OR=4.375,95%CI 2.873-6.664) were identified as risk factors for depression among children and adolescents. Conclusion The presence of anxiety symptoms, social anxiety symptoms, obsessive symptoms, hostility, and eating and sleeping issues increases the risk of de- pression among children and adolescents. [ABSTRACT FROM AUTHOR]

Bipolar disorder (BD) is a complex mental illness characterized by mood fluctuations, excitability and impaired functioning. Anxiety in BD patients frequently leads to increased clinical symptoms, worse social functioning, and a higher risk of suicide. Current research on BD with anxiety symptom primarily examined clinical characteristics, prevalence and treatment, with limited focus and inconsistent findings on its neuro-biogenetic mechanisms. The findings in this area were also inconsistent. Magnetic resonance imaging (MRI), known for its non-invasive nature and high resolution, is extensively utilized in investigating disease mechanisms. Consequently, this paper gave a comprehensive review on the progress in brain imaging on BD patients with anxiety symptom, seeking to discern stable changes in brain structure and function, thereby enrich our understanding of the neurobiological etiology of this condition and offer valuable insights for clinical diagnosis and treatment strategies making. This paper covered 14 original studies and synthesized their findings on brain structure and function. Conclusively, the changes of brain functional activities in BD patients with anxiety symptom mainly involve the prefrontal lobe, posterior cingulate cortex, temporal lobe and angular gyrus, while the changes of brain structure mainly involve the left hippocampus and middle frontal gyrus, but the consistency of the research results needs to be enhanced. The research in this field is not sufficient, and more homogeneous clinical samples and larger longitudinal studies are needed to verify and supplement the above results. [ABSTRACT FROM AUTHOR]

Background Suicidal ideation serves as a sensitive predictive indicator for non-suicidal self-injury (NSSI) behavior, and NSSI behavior brings profound effects to both mental and physical health of senior high school students. Existing studies have made exploration on the relationship among insomnia, anxiety and NSSI behavior in the general population, but the internal mechanism of NSSI behavior in senior high school students with suicidal ideation requires further study. Objective To explore the pathway of anxiety between insomnia and NSSI behavior in senior high school students, so as to provide references for the intervention on NSSI behavior in such demographic. Methods From December 10 to 15, 2021, cluster sampling was adopted to select 2 572 senior high school students across three senior high schools in Hubei Province as the research objects. Assessment was conducted by using Insomnia Severity Index (ISI), Generalized Anxiety Disorder Scale-7 item (GAD-7) and Adolescents Self-Harm Scale. Spearman correlation analysis was conducted to examine the correlation among scores of scales finished by senior high school students with suicidal ideation. Model 4 from the SPSS 20. 0 Process 4. 2 was employed to test the mediating path of anxiety between insomnia and NSSI behavior. Results A total of 2 421 valid questionnaires (94. 13%) were recovered, which revealed 554 cases (22. 88%) with suicidal ideation and 408 cases (16. 85%) with NSSI behavior. The scores of ISI, GAD-7 and Adolescents Self-Harm Scale of senior high school students with suicidal ideation were higher than those of students without suicidal ideation (Z=17. 124, 20. 611, 21. 314, P<0. 01). As correlation analysis showed, the ISI score of senior high school students with suicidal ideation was positively correlated with scores of GAD-7 and Adolescents Self-Harm Scale (r=0. 646, 0. 354, P<0. 01), and GAD-7 score was positively correlated with the score of Adolescents Self-Harm Scale (r=0. 375, P<0. 01). Among senior high school students with suicide ideation, anxiety acted in a mediating role between insomnia and NSSI behavior, with effect value of 0. 111（95% CI: 0. 053~ 0. 185), accounting for 53. 88% of the total effect. Conclusion Insomnia of senior high school students with suicidal ideation can not only directly affect NSSI behavior, but also indirectly affect NSSI behavior through anxiety. [ABSTRACT FROM AUTHOR]

Objective To explore the potential categories of self-efficacy and anxiety in pregnant women in the third trimester, and analyze the characteristics of different categories of pregnant women. Methods Convenience sampling method was used to select women in the third trimester of pregnancy from antenatal clinics of three tertiary hospitals in Nantong city. General data questionnaire, anxiety scale, general self-efficacy scale, pregnancy stress scale, perceived social support scale, and mental resilience scale were used for investigation. Anxiety and self-efficacy were used as explicit indicators for potential profile analysis, and ordered multiple Logistic regression analysis was used to explore the relevant influencing factors. Results Pregnant women’s self-efficacy and anxiety in the third trimester were divided into three potential categories: low self-efficacy-high anxiety group (32.5%), medium self-efficacy-medium anxiety group (46.8%), and high self-efficacy-low anxiety group (20.7%). The results of ordered multiple Logistic regression analysis showed that educational level (OR=0.690, 95%CI: 0.483-0.987), gestational incontinence (OR=0.718, 95%CI: 0.510-1.009), pregnancy stress (OR=0.980, 95%CI: 0.964-0.996), social support (OR=1.036, 95%CI: 1.003-1.071), and mental resilience (OR=1.323, 95%CI: 1.264-1.386; OR=1.761, 95%CI: 1.647-1.882; OR=0.752, 95%CI: 0.716-0.789) of pregnant women were the influencing factors of self-efficacy and anxiety in the third trimester of pregnancy. Conclusion There are obvious classification characteristics of pregnant women’s self-efficacy and anxiety in the third trimester. According to the influencing factors, medical staff should conduct psychological counseling and corresponding support intervention for different types of pregnant women to improve the self-efficacy of pregnant women and reduce the anxiety of pregnant women. [ABSTRACT FROM AUTHOR]

Objective To investigate the effect of preoperative anxiety on postoperative recovery and short-term prognosis in patients with liver cancer resection. Methods A total of 96 patients underwent elective open hepatocellular carcinoma resection, with American Society of Anesthesiologists (ASA) grade Ⅰ-Ⅱ were included in this study. Patients were divided into the control group (41 cases, HAMA < 7 points) and the anxiety group (55 cases, HAMA ≥7 points) according to Hamilton Anxiety Scale (HAMA). Heart rate (HR), mean arterial pressure (MAP) after entering the operating room, operative time, intraoperative bleeding, intraoperative fluid infusion and intraoperative remifentanil consumption were monitored in patients. Recovery time, extubation time, Emergence Agitation (EA) score, the resting and dynamic visual analogue scale ( VAS ) at 5 min after extubation (T1), 6 h (T2), 12 h (T3), 24h (T4) and 48 h (T5) after surgery, the cumulative effective pressing times of patient controlled analgesia (PCA), the remedy times of analgesic drugs, the postoperative gastrointestinal reaction, exhaust time, hospital stay, the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels at the 5th day after operation were recorded. Results Compared with the control group, the heart rate and MAP in the anxious group were significantly increased after entering operating room, and the recovery time and extubation time were significantly prolonged (P＜0.05). The incidence of intraoperative remifentanil consumption, EA score, T1, T2, T3 resting and dynamic VAS score, T4 dynamic VAS score, PCA pressing times, analgesic drug remedy times and postoperative gastrointestinal reactions were significantly higher in the anxious group than those in the control group (P＜ 0.05), and incidence of gastrointestinal reactions, postoperative out of bed time, exhaust time, feeding time and hospital stay were significantly prolonged (P＜0.05). Conclusion Preoperative anxiety is not conducive to anesthesia recovery and shortterm prognosis in patients with liver tumor resection. [ABSTRACT FROM AUTHOR]

Elderly patients with functional constipation generally have mental and psychological disorders, especially the prevalence of anxiety and depression disorders is much higher than that of normal population. Anxiety and depression can affect gastrointestinal motility and sensation by affecting brain-gut axis. enteric nervous system, hormone neurotransmitters and intestinal flora, leading to functional constipation. The author reviewed the research on the comorbidity of functional constipation and anxiety and depression in the elderly at home and abroad and discussed the application of psychosomatic integration model in clinical practice in order to provide a reference for improving the clinical treatment practice of functional constipation in the elderly. [ABSTRACT FROM AUTHOR]

Objective To investigate the efficacy of the information knowledge beliefs behaviors (IKAP) combined with the trans-theoretical model (TTM) clinical intervention in patients undergoing hyperthermic intraperitoneal perfusion chemotherapy(HIPEC). Methods A total of 224 patients who received HIPEC in the Department of Oncology of the hospital from February 2022 to February 2023 were selected as the research objects. They were divided into study group and control group by random number table method, with 112 cases in each group. The control group received routine clinical treatment and the study group was given clinical intervention of IKPA combined with TTM on the basis of routine clinical treatment. The incidence of adverse reactions. anxiety and depression(self-rating anxiety scale. self-rating depression scale score) and self-efficacy (self-efficacy scale score) were compared between the two groups. Results The incidence of adverse reactions [11.61%(13/112)], the scores of self-rating anxiety scale and self-rating depression scale after intervention [(45.55±5.51),(41.65±5.36) points in the study group were significantly lower than those in the control group [33.93% (38/112),(48.47±6.03),(44.38±5.97) points+respectively and the scores of self-efficacy scale [(28.90±4.87) points] were significantly higher than those in the control group (26.41±4.52) points], the differences were statistically significant (P<0.05). Conclusion The clinical intervention of IKAP combined with TTM can effectively reduce the incidence of adverse reactions in patients with HIPEC. improve patients anxiety and depression improve patients self efficacy. [ABSTRACT FROM AUTHOR]

Objective To investigate the effects of P2X7 receptor (P2X7R) inhibitor on kainic acid-induced epilep-togenesis and hippocampal damage in mice. Methods Ninety-six male C57BL/6 mice were randomly divided into the control group of 36, the model group of 36, and the P2X7R inhibitor group of 24. Mice in the P2X7R inhibitor group were injected intraperitoneally with A438079, a P2X7R-specific inhibitor, 30 min before modeling, and mice in the model and control groups were injected with the equal volume of normal saline at the same time point. The epilepsy model was estab⁃ lished by intraperitoneal injection of kainic acid in the model group and the P2X7R inhibitor group, and an equal volume of normal saline was injected intraperitoneally in mice of the control group. The severity of seizures was assessed according to the electroencephalography (EEG), Western blotting was used to determine the level of hippocampal P2X7R expression, and Nissl staining was used to assess the extent of hippocampal damage in the CA1 region. Anxiety-like behaviors of mice in the control and model groups were observed in the open-field test. If anxiety-like behaviors existed in the model group, the model group was further divided into the anxiety control subgroup and P2X7R-inhibited subgroup; mice in the P2X7Rinhibited subgroup were injected with A438079 intraperitoneally every day, and mice in the anxiety control subgroup were injected with an equal volume of normal saline every day intraperitoneally, and open-field test was conducted again after 14 days. The morris water maze was used to observe the cognitive function of the mice, and if there was cognitive impairment in the model group, the model group was further divided into the cognitive control subgroup and P2X7R-inhibited subgroup. Mice in the P2X7R-inhibited subgroup were injected intraperitoneally with 15 mg/kg of A438079 every day, while mice in the cognitive control subgroup were injected with the equal volume of normal saline every day, and then the morris water maze was performed again after 14 days. Results The EEG did not show any epileptiform activity in the control group. Mice in the model group developed status epilepticus, in which EEG showed strong discharge power and high ampli⁃ tude. Seizures occurred in the P2X7R inhibitor group, but the power and amplitude of EEG were attenuated compared with those in the model group; total power and mean amplitude were as follows： the model group > P2X7R inhibitor group > con⁃ trol group (both P<0. 05), The expression of P2X7R protein in the hippocampal tissues was higher than that in the control group, and the expression of P2X7R protein was lower in the P2X7R inhibitor group than in the model group (both P< 0. 05), The results of nissl staining showed that the structure of hippocampal CA1 region was intact, the number of surviving neuronal cells was large, and the nissl body was big and its number was large in the control group; the structural integrity of hippocampal CA1 region was disrupted, the number of neuronal cells was small, and the number of nissl body decreased in the model group; the structure of the hippocampal CA1 region, the number of neuronal cells, and the number of nissl body in the P2X7R inhibitor group improved in comparison with those in the model group. The results of the open-field test showed that the number of entering the central region and the length of stay in the central region were less in the model group than in the control group, and the number of entering the central region and the length of stay in the central region were less in the anxiety control subgroup than in the P2X7R-inhibited subgroup (all P<0. 05), The results of the morris water maze showed that there were no statistically significant differences in the number of platform crossings or the length of stay in target quadrant between the model and control groups (all P>0. 05), Conclusion P2X7R inhibitor reduces the severity and frequency of kainic acid-induced seizures, ameliorates epilepsy-induced hippocampal damage, and alleviates anxiety-like behavior in epileptic mice. [ABSTRACT FROM AUTHOR]