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为了开发新型高相似性人乳脂肪替代物，依据中国人乳脂肪的脂肪酸组成和甘油三酯结构，以巴沙鱼油、樟树籽仁油、亚麻籽油、微生物油（富含ARA）及DHA藻油(质量比为153.81∶ 15.16 ∶ 62.33∶ 7.89 ∶ 1081)为原料油脂，以固定化脂肪酶Lipozyme RM为催化剂，在60 ℃下酯交换反应8 h 制备人乳脂肪替代物，测定其脂肪酸、sn-2位脂肪酸及甘油三酯组成及含量，分析其红外光谱图、熔融性质、结晶性质及流变学性能。结果表明，构建的人乳脂肪替代物中链脂肪酸含量为12%、亚油酸和亚麻酸总含量为19.53%且比例约为1∶ 1.5，ARA含量为1.17%，DHA含量为111%，其 sn-2位富含棕榈酸（43.10%），结构甘油三酯含量高（58.75%），无反式脂肪酸生成，熔融温度低于人体温度且在20 ℃下仍能保持18.7%的固体脂肪含量，结晶形态细腻且流变性能优异。制备的人乳脂肪替代物具有应用于婴幼儿配方奶粉、婴幼儿米糊和婴幼儿饼干等各种婴幼儿食品的潜力。 For the development of new high-similarity human milk fat substitutes， based on the fatty acid composition and triglyceride structure of Chinese human milk fat, five kinds of oils, including basha fish oil, Cinnamomum camphora seed kernel oil, linseed oil, microbial oil(rich in ARA), DHA algae oil, with mass ratio of 153.81∶ 15.16∶ 62.33∶ 7.89∶ 10.81 were used to prepare the human milk fat substitutes (HMFS) catalyzed by immobilized lipase Lipozyme RM at 60 ℃ for 8 h，and its fatty acid, sn-2 fatty acid and triglyceride compositions and contents were determined, as well as the infrared spectra, melting properties, crystalline properties, and rheological properties. The results showed that the HMFS contained 12% of medium-chain fatty acids, 19.53% of linoleic acid-linolenic acid with ratio 1∶ 1.5, 1.17% of ARA and 1.11% of DHA, and its sn-2 position had high content of palmitic acid (43.10%), and it had high content of structured triglycerides(58.75%)，and no trans fatty acid were formed. The melting temperature of HMFS was below body temperature and the solid fat content of HMFS at 20 ℃ was 187%. In addition, the crystals form of HMFS were fine and uniform, the rheological properties of HMFS were excellent. The HMFS obtained has potential application in various infant foods such as infant formula, infant rice cereal and infant biscuits.

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Objective: To investigate the correlated factors of fungal rhinosinusitis and to analyze its clinical features. Methods: A group of 150 patients with fungal rhinosinusitis treated by surgery and another group of 150 patients with chronic rhinosinusitis in our hospital were selected and their clinical data were analyzed and compared retrospectively. The multiple factor Logistic regression analysis and square test were used to analyze the clinical data of all the patients. The correlated factors and the clinical features of fungal rhinosinusitis were investigated. Gomori methenamine silver staining which was special for fungi was used to classify the pathological types of 150 patients with fungal rhinosinusitis. Results: Age（x1）, the course of the disease（x2）, haem-nasal discharge（x3）, headache（x4）, unilateral/bilateral sinus lesion（x5） and calcified plaque in CT scan（x6） were set as the concomitant variables respectively, and then we established the Logistic regression predictive equation for fungal rhinosinusitis, which was y=-8.714+1.201 x1+0.497 x2+4.576 x3+1.188x4+2.697x5+4.118 x6, P=exp（y）/[1+exp（y）]. The P value meant the probability of suffering fungal rhinosinusitis. Compared with chronic rhinosinusitis, the clinical features of fungal rhinosinusitis were female, over 40 years old, the course of disease <3 years, headache, haem-nasal discharge, unilateral sinus lesion and calcified plaque in CT scan（P<0.05）. Among the 150 patients with fungal rhinosinusitis, 46 cases were chronic invasive and 104 were non-invasive. Conclusions: The clinical features of fungal rhinosinusitis can be predicted by using the suitable logistic predictable equation and they are significant for the diagnosis of fungal rhinosinusitis. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To analysis the effect of blood glucose level on liver function and blood lipid in type Ⅱ diabetes mellitus patients. Methods: 408 patients newly diagnosed with type Ⅱ diabetes mellitus aged from 14 to 89 years from November 2013 to May2014 were collected. All patients were divided into three groups according to the concentration of fasting plasma glucose(FPG)(group A, the FPG<8.0 mmol/L; group B, 8.0mmol/L≤FPG<11.0 mmol/L, group C, FPG≥11.0 mmol/L). The liver function and blood lipids were detected, then analysis for the influence and statistical significance between liver function, blood lipid and type Ⅱ diabetes mellitus patients’ blood glucose level were performed by SPSS 17.0. Results: Compared with group A and group B, group C was more obvious in the rise of ALT, AST(P<0.05), characterized by a significant rise in liver enzymes and bilirubin(P<0.05),and GLB level had significant increase(P<0.05); TC and TG level were abnormal(P<0.05). Conclusions: TypeⅡ diabetes mellitus patients with higher blood glucose level can cause more serious liver damage and dyslipidemia. The surveillance and control of blood glucose have an important significance for the health of the typeⅡ diabetes mellitus patients. [ABSTRACT FROM AUTHOR]