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【目的】探讨乏氧组织显像剂99mTc-HL91显像对肺癌诊断价值及与放射治疗前后肿瘤乏氧程度的改变。【方法】选取确诊的肺癌病例41例,非肺癌病例33例为实验组和对照组。实验组于放射治疗前后1,6h行99mTc-HL91肺癌乏氧显像并测定其T/NT比值,放疗后前后4h行CT＋SPECT断层显像并测定T/NT比值;对照组行肺部1,6h99mTc-HL91肺癌乏氧显像。【结果】41例肺癌患者治疗前均可见病灶处放射性分布早期增加,血流灌注峰与邻近正常组织比较明显增加。治疗前1、6h平面显像T/NT值分别为1.2024±0.0745,1.4659±0.0820;治疗后1、6分别为1.0895±0.0553,1.2163±0.0694。治疗前后比较,P=0.000。对照组33例,1、6h平面显像双肺对应感兴趣区T/NT分别为0.978±0.055和0.980±0.030。肺癌组与对照组1h,6hT/NT值比较,差异有显著性,P=0.000。放疗后1、6h分别为1.0895±0.0553,1.2163±0.0694。治疗前后比较,P=0.000。放疗后1h,低度乏氧（1.0888〈T/NT≤1．2024）18例，其疗效CR9例，PR8例，SD1例，PD0例；高度乏氧（T／nt〉1．2024）23例，其疗效CR0例，PR18例，SD3例，PD2例。放疗后6h低度乏氧（1．0898〈TINT≤1．4659）22例，其疗效CR9例，PR12例，SD1例，PD0例；高度乏氧（T／NT〉I．4659）19例，其疗效CR0例，PR14例，SD3例，PD2例。放疗疗效和乏氧程度分布有显著统计学差异（P〈0．05）。【结论】^99mTc-HL91能检测肺癌乏氧与否及其程度。可作为评价肺癌乏氧程度的一种辅助手段：肺癌患者放疗前后^99mTc-HL91乏氧显像T/NT值分布有明显差异，其乏氧程度和放疗疗效关系密切，可作为肺癌放疗疗效预测的手段之一。

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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In border irrigation, an optimal pattern is necessary for high irrigation and fertilization uniformity, nitrogen storage efficiency and crops yield. This paper aims to explore the effects of different border specifications and fertilization methods on the distribution of soil NO3 --N and the yield of winter wheat. Therefore, a field experiment was conducted in 2017-2018 at the winter wheat season. Three experimental factors were selected, including the border width of field (1.5, 2.3, and 3.2 m), border length (40, 60, and 80 m) and the fertilization timing (first half liquid fertilizer application, second half liquid fertilizer application, full liquid fertilizer application). Three factors were set by orthogonal experiment design, and twelve treatments were established, including three traditional broadcasting fertilization as control treatments (border width of 1.5, 2.3 and 3.2 m at 80 m border length with spreading application). The content of soil NO3 --N, the uniformity of NO3 --N distribution, nitrogen storage efficiency and winter wheat yield were measured in this study. The results showed that the concentrations of soil NO3 --N increased in different soil layers after irrigation, compared with those before irrigation, while soil NO3 --N concentrations decreased with the increase of soil depth. In liquid application treatments, the accumulation of soil NO3 --N in the root layer was 0.27%-27.97% higher than that in the spreading application treatments. The border width, border length and fertilization timing all significantly determined the fertilization uniformity and storage efficiency of NO3 --N in border irrigation. In the wheat reviving stage, the contribution rate of border length to the uniformity of irrigation and fertilization was the maximum (91.64%), whereas the contribution rate of fertilization timing on nitrogen storage efficiency was the highest (44.2%). In the flowering stage, the border length and border width were the main factors that affected the uniformity of irrigation and fertilization, and the nitrogen storage efficiency, where the contribution rates were 92.67% and 53.6%, respectively, indicating that the border length dominated in this case. The uniformity of irrigation and fertilization under 60 m border length treatments was higher than that under 40 m and 80 m of border length treatments. The contribution rates of border width, border length, and fertilization timing to the crop yield were 37.2%, 37.3%, and 23.9%, respectively. The highest yield (7869.2 kg/hm²) was achieved under the border width of 3.2 m, border length of 60 m and full liquid application treatment. The finding demonstrated that the liquid application can improve the distribution uniformity of soil NO3 --N, and soil NO3 --N accumulation in the root layer of winter wheat, while avoid soil NO3 --N leaching. The optimal treatment mode can be the combination of 3.2 m border width, 60 m border length and full liquid fertilizer application for the uniformity and accumulation of soil NO3 --N, as well crop yield. The results of this study can offer a theoretical basis to select border dimensions and fertilization timing for the winter wheat in North China Plain. [ABSTRACT FROM AUTHOR]

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The application of informatization technology to university laboratory management is an inevitable trend of the development of colleges and universities, and it is also an important symbol to measure the management level of colleges and universities. The information becomes the new support for the efficiency improvement of university laboratory management, and some innovations are brought. Under the background of informatization, based on the practical experience of the management of university laboratory low-value materials, this paper analyzes the present situation of laboratory low-value material shortage in universities, and deals with the significance of establishment of informatization management system. Combining with the exploration and the practice in Huaqiao University, this paper illustrates how to use advanced information technology, to regulate the management and build the information management platform such that the decentralized procurement of low-value materials can be concentrated checked and restored. By optimizing the management process, improving the efficiency of management, the standardization of laboratory low-value material, intensive and fine management are realized. [ABSTRACT FROM AUTHOR]

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