1. Structure prediction algorithm for protein complexes based on gene ontology
- Author
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Ilya A. Vakser, Alexander V. Tuzikov, Ivan Anishchenko, A. Yu. Hadarovich, and Petras J. Kundrotas
- Subjects
0303 health sciences ,03 medical and health sciences ,Docking (dog) ,Template ,Gene ontology ,Computer science ,030302 biochemistry & molecular biology ,Computational biology ,Measure (mathematics) ,Functional similarity ,030304 developmental biology ,Protein–protein interaction - Abstract
We propose an algorithm for comparing protein-protein complexes based on their functional properties in terms of Gene Ontology. The proposed measure of a functional similarity between complexes is combined with a structural measure to find templates for the template-based docking of protein complexes. We present the results on the modeling of protein complexes based on this algorithm.
- Published
- 2020
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