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4. Relationship between salt consumption and iodine intake in a pediatric population

Author

Iacone, R., Iaccarino Idelson, P., Campanozzi, A., Rutigliano, I., Russo, O., Formisano, P., Galeone, D., Macchia, P. E., Strazzullo, P., Agabiti-Rosei, E., Carcea, M., Donfrancesco, C., Galletti, F., Giampaoli, S., Iacoviello, L., Scalfi, L., Siani, A., De Filippo, G., Malamisura, B., Cecere, G., Micillo, M., D'Angelo, E., Maschione, R., De Marco, G., D'Angelo, G., Cosenza, C., Gualano, R., Borsetti, R., Cela, G., Francavilla, R., Tetro, A., Pensabene, L., Talarico, V., Graziano, F., Palermo, B. V. E., Lombardi, G., Illiceto, M. T., Tonelli, L., Catassi, C., Tonelli, G., Castellucci, G., Ferraro, L., Cozzali, R., Di Biase, R., Cipolli, S., Lezo, A., Santini, B., Salvatore, S., Morando, L., Paoletti, S., Gallese, A., Mazzone, T., Iacone, Roberto, IACCARINO IDELSON, Paola, Campanozzi, Angelo, Rutigliano, Irene, Russo, Ornella, Formisano, Pietro, Galeone, Daniela, Macchia, PAOLO EMIDIO, and Strazzullo, Pasquale

Subjects
Adolescent, Endocrinology, Diabetes and Metabolism, Salt (chemistry), Nutritional Status, Medicine (miscellaneous), Context (language use), Sodium Chloride, World health, Animal science, 24 h urinary excretion, Environmental health, salt, Humans, Medicine, Sodium Chloride, Dietary, Salt intake, Child, Iodine intake, chemistry.chemical_classification, Thyroid, Consumption (economics), Nutrition and Dietetics, iodine prophylaxi, business.industry, Salt reduction, Iodine deficiency disorders, Original Contribution, Iodised salt, pediatric, chemistry, Italy, iodine deficiency disorder, Salt restriction, Hypertension, Iodine prophylaxis, Cardiology and Cardiovascular Medicine, business, Pediatric age, Iodine, Pediatric population
Abstract

Purpose The World Health Organization recommends reduction of salt intake to Methods The study population was made of 1270 children and adolescents. Estimates of salt consumption and iodine intake were obtained by measuring 24 h urinary sodium and iodine excretion. Results The iodine intake increased gradually across quartiles of salt consumption independently of sex, age and body weight (p 10.2 g/day). We estimated that approximately 65–73% of the total iodine intake was derived from food and 27–35% from iodized salt and that iodized salt made actually only 20% of the total salt intake. Conclusion In this pediatric population, in face of an elevated average salt consumption, the use of iodized salt was still insufficient to ensure an adequate iodine intake, in particular among teenagers. In the perspective of a progressive reduction of total salt intake, the health institutions should continue to support iodoprophylaxis, in the context of the national strategies for salt reduction. In order for these policies to be successful, in addition to educational campaigns, it is needed that the prescriptions contained in the current legislation on iodoprophylaxis are made compelling through specific enforcement measures for all the involved stakeholders.

Published
2020

8. Validation of an easy questionnaire on the assessment of salt habit: the MINISAL-SIIA Study Program

Author

D’Elia, L., Manfredi, M., Strazzullo, P., Galletti, F., Agabiti-Rosei, E., Arcangeli, E., Artom, A., Barbato, A., Barbiero, M., Belfiore, A., Bernini, G., Boero, R., Berra, E., Biggi, A., Borgheresi, P., Borghi, C., Bosio, A., Caiazza, A., Caielli, P., Caló, L. A., Castellano, M., Catena, C., Cerrato, F., Cilia, C., Cipollini, F., Crippa, M., Cuspidi, C., D’Avino, M., De Giorgi, G. A., De Luca, N., De Pergola, G., Del Giudice, A., Desideri, G., Fallo, F., Ferri, C., Galeone, D., Garavelli, G., Gaudio, G., Giacchetti, G., Gidaro, B., Giovannetti, R., Grandi, A., Guglielmi, M., Iacoviello, L., Leonardis, D., Lonati, C., Lonati, L. M., Malatino, L., Mallamaci, F., Maresca, A. M., Marzano, L., Massara, C., Merletti, L., Meschi, M., Modesti, S., Montanari, A., Morganti, A., Musiari, L., Musso, N., Nardecchia, A., Nazzaro, P., Pallisco, O., Panichi, V., Parati, G., Pascale, C., Pini, C., Pirola, I., Pucci, G., Rabbia, F., Rescaldani, M., Ronchi, E., Rossi, E., Rossi, G., Sala, C., Sarzani, R., Sechi, L. A., Silvestris, F., Stancanelli, B., Trimarco, B., Ungar, A., Veglio, F., Veronesi, M., Vinella, L., D'Elia, L, Manfredi, M, Strazzullo, P, Galletti, F, Agabiti-Rosei, E, Arcangeli, E, Artom, A, Barbato, A, Barbiero, M, Belfiore, A, Bernini, G, Boero, R, Berra, E, Biggi, A, Borgheresi, P, Borghi, C, Bosio, A, Caiazza, A, Caielli, P, Calo, L, Castellano, M, Catena, C, Cerrato, F, Cilia, C, Cipollini, F, Crippa, M, Cuspidi, C, D'Avino, M, De Giorgi, G, De Luca, N, De Pergola, G, Del Giudice, A, Desideri, G, Fallo, F, Ferri, C, Galeone, D, Garavelli, G, Gaudio, G, Giacchetti, G, Gidaro, B, Giovannetti, R, Grandi, A, Guglielmi, M, Iacoviello, L, Leonardis, D, Lonati, C, Lonati, L, Malatino, L, Mallamaci, F, Maresca, A, Marzano, L, Massara, C, Merletti, L, Meschi, M, Modesti, S, Montanari, A, Morganti, A, Musiari, L, Musso, N, Nardecchia, A, Nazzaro, P, Pallisco, O, Panichi, V, Parati, G, Pascale, C, Pini, C, Pirola, I, Pucci, G, Rabbia, F, Rescaldani, M, Ronchi, E, Rossi, E, Rossi, G, Sala, C, Sarzani, R, Sechi, L, Silvestris, F, Stancanelli, B, Trimarco, B, Ungar, A, Veglio, F, Veronesi, M, Vinella, L, L. D’Elia, M. Manfredi, P. Strazzullo, F. Galletti, E. Agabiti-Rosei, E. Arcangeli, A. Artom, A. Barbato, M. Barbiero, A. Belfiore, G. Bernini, R. Boero, E. Berra, A. Biggi, P. Borgheresi, C. Borghi, A. Bosio, A. Caiazza, P. Caielli, L. A. Caló, M. Castellano, C. Catena, F. Cerrato, C. Cilia, F. Cipollini, M. Crippa, C. Cuspidi, M. D’Avino, G. A. De Giorgi, N. De Luca, G. De Pergola, A. Del Giudice, G. Desideri, F. Fallo, C. Ferri, D. Galeone, G. Garavelli, G. Gaudio, G. Giacchetti, B. Gidaro, R. Giovannetti, A. Grandi, M. Guglielmi, L. Iacoviello, D. Leonardi, C. Lonati, L. M. Lonati, L. Malatino, F. Mallamaci, A. M. Maresca, L. Marzano, C. Massara, L. Merletti, M. Meschi, S. Modesti, A. Montanari, A. Morganti, L. Musiari, N. Musso, A. Nardecchia, P. Nazzaro, O. Pallisco, V. Panichi, G. Parati, C. Pascale, C. Pini, I. Pirola, G. Pucci, F. Rabbia, M. Rescaldani, E. Ronchi, E. Rossi, G. Rossi, C. Sala, R. Sarzani, L. A. Sechi, F. Silvestri, B. Stancanelli, B. Trimarco, A. Ungar, F. Veglio, M. Veronesi, and L. Vinella

Subjects
Male, 0301 basic medicine, Validation study, medicine.medical_specialty, media_common.quotation_subject, Medicine (miscellaneous), 030209 endocrinology & metabolism, Nutrition and Dietetic, hypertension, sodium intake, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, Internal medicine, Nutrition and Dietetic, medicine, Humans, MINISAL-SIIA, Sodium Chloride, Dietary, Nutrition, media_common, 030109 nutrition & dietetics, Nutrition and Dietetics, Urinary sodium, business.industry, MINISAL-SIIA Study Program, Reproducibility of Results, Middle Aged, Anthropometry, Blood pressure, Italy, Hypertension, Dietary salt intake, Female, Habit, dietary salt intake, business, Dietetic, sodium intake
Abstract

Background/objectives: The aim of the present study was to validate a short questionnaire on habitual dietary salt intake, to quickly and easily identify individuals whose salt consumption exceeds recommended levels. Subjects/methods: A total of 1131 hypertensive subjects participating in the MINISAL-SIIA study were included in the analysis. Anthropometric indexes, blood pressure, and 24-h urinary sodium excretion (NaU) were measured. A fixed-sequence questionnaire on dietary salt intake was administered. Results: NaU was significantly associated with scores, with a linear association across categories (p for trend 85 mmol/day) and “very high NaU” (NaU > 170 mmol/day) was 86 and 35%, respectively. The score of the questionnaire had a significant ability to detect both “high NaU”—with a specificity of 95% at the score of 10 points—and “very high NaU”—with a specificity of 99.6% at score of 13 points. Conclusions: The main results of the study indicates that a higher score of this short questionnaire is distinctive of habitual high salt consumption in hypertensive patients.

Published
2019

11. Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

Author

Borghi C, Agabiti-Rosei E, Johnson R, Kielstein J, Lurbe E, Mancia G, Redon J, Stack A, and Tsioufis K

Subjects
nutritional and metabolic diseases, urologic and male genital diseases
Abstract

During the last century, there has been an increasing prevalence of hyperuricaemia noted in many populations. While uric acid is usually discussed in the context of gout, hyperuricaemia is also associated with hypertension, chronic kidney disease, hypertriglyceridaemia, obesity, atherosclerotic heart disease, metabolic syndrome, and type 2 diabetes. Here we review the connection between hyperuricaemia and cardiovascular, kidney and metabolic diseases. Contrary to the popular view that uric acid is an inert metabolite of purine metabolism, recent studies suggest serum uric acid may have a variety of pro-inflammatory, pro-oxidative and vasoconstrictive actions that may contribute to cardiometabolic diseases. Hyperuricaemia is a predictive factor for the development of hypertension, metabolic syndrome, type 2 diabetes, coronary artery disease, left ventricular hypertrophy, atrial fibrillation, myocardial infarction, stroke, heart failure and chronic kidney disease. Treatment with uric acid-lowering therapies has also been found to improve outcomes in patients with hypertension and kidney disease, in some but not all studies. In conclusion, uric acid is emerging as a potentially treatable risk factor for cardiometabolic diseases, and more clinical trials investigating the potential benefit of lowering serum uric acid are recommended in individuals with hyperuricaemia with and without deposition and concomitant hypertension, metabolic syndrome or chronic kidney disease. Copyright © 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Published
2020

12. Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

Author

Borghi, C. Agabiti-Rosei, E. Johnson, R.J. Kielstein, J.T. Lurbe, E. Mancia, G. Redon, J. Stack, A.G. Tsioufis, K.P.

Subjects
nutritional and metabolic diseases, urologic and male genital diseases
Abstract

During the last century, there has been an increasing prevalence of hyperuricaemia noted in many populations. While uric acid is usually discussed in the context of gout, hyperuricaemia is also associated with hypertension, chronic kidney disease, hypertriglyceridaemia, obesity, atherosclerotic heart disease, metabolic syndrome, and type 2 diabetes. Here we review the connection between hyperuricaemia and cardiovascular, kidney and metabolic diseases. Contrary to the popular view that uric acid is an inert metabolite of purine metabolism, recent studies suggest serum uric acid may have a variety of pro-inflammatory, pro-oxidative and vasoconstrictive actions that may contribute to cardiometabolic diseases. Hyperuricaemia is a predictive factor for the development of hypertension, metabolic syndrome, type 2 diabetes, coronary artery disease, left ventricular hypertrophy, atrial fibrillation, myocardial infarction, stroke, heart failure and chronic kidney disease. Treatment with uric acid-lowering therapies has also been found to improve outcomes in patients with hypertension and kidney disease, in some but not all studies. In conclusion, uric acid is emerging as a potentially treatable risk factor for cardiometabolic diseases, and more clinical trials investigating the potential benefit of lowering serum uric acid are recommended in individuals with hyperuricaemia with and without deposition and concomitant hypertension, metabolic syndrome or chronic kidney disease. © 2020 European Federation of Internal Medicine

Published
2020

13. Nutraceuticals and blood pressure control: A European Society of Hypertension position document

Author

Borghi, C., Prof. Tsioufis, K. Agabiti-Rosei, E. Burnier, M. Cicero, A.F.G. Clement, D. Coca, A. Desideri, G. Grassi, G. Lovic, D. Lurbe, E. Kahan, T. Kreutz, R. Jelakovic, B. Polonia, J. Redon, J. Van De Borne, P. Mancia, G.

Abstract

High-normal blood pressure (BP) is associated with an increased risk of cardiovascular disease, however the cost-benefit ratio of the use of antihypertensive treatment in these patients is not yet clear. Some dietary components and natural products seems to be able to significantly lower BP without significant side effects. The aim of this position document is to highlight which of these products have the most clinically significant antihypertensive action and wheter they could be suggested to patients with high-normal BP. Among foods, beetroot juice has the most covincing evidence of antihypertensive effect. Antioxidant-rich beverages (teas, coffee) could be considered. Among nutrients, magnesium, potassium and vitamin C supplements could improve BP. Among nonnutrient-nutraceuticals, soy isoflavones could be suggested in perimenopausal women, resveratrol in insulin-resistant patients, melatonin in study participants with night hypertension. In any case, the nutracutical approach has never to substitute the drug treatment, when needed. © 2020 Lippincott Williams and Wilkins. All rights reserved.

Published
2020

25. 2018 Practice Guidelines for the management of arterial hypertension of the European Society of Hypertension and the European Society of Cardiology: ESH/ESC Task Force for the Management of Arterial Hypertension

Author

Williams, B, Mancia, G, Spiering, W, Agabiti Rosei, E, Azizi, M, Burnier, M, Clement, D, Coca, A, De Simone, G, Dominiczak, A, Kahan, T, Mahfoud, F, Redon, J, Ruilope, L, Zanchetti, A, Kerins, M, Kjeldsen, S, Kreutz, R, Laurent, S, Lip, G, McManus, R, Narkiewicz, K, Ruschitzka, F, Schmieder, R, Shlyakhto, E, Tsioufis, K, Aboyans, V, Desormais, I, and Members, L

Published
2018

30. Non-invasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients: A consensus paper from the European Association of Cardiovascular Imaging (EACVI), the European Society of Cardiology Council on Hypertension, and the European Society of Hypertension (ESH)

Author

Perrone-Filardi P, Coca A, Galderisi M, Paolillo S, Alpendurada F, de Simone G, Donal E, Kahan T, Mancia G, Redon J, Schmieder R, Williams B, Agabiti-Rosei E, Perrone Filardi, P, Coca, A, Galderisi, M, Paolillo, S, Alpendurada, F, De Simone, G, Donal, E, Kahan, T, Mancia, G, Redon, J, Schmieder, R, Williams, B, and Agabiti Rosei, E

Subjects
cardiovascular risk, Male, arterial hypertension, Consensus, Cardiology, Risk Assessment, Europe, Cardiac Imaging Techniques, Cardiovascular Diseases, target organ damage, Asymptomatic Diseases, Hypertension, Practice Guidelines as Topic, Humans, Female, non-invasive cardiovascular imaging, prognosi, Societies, Medical
Abstract

Arterial hypertension (HTN) accounts for the largest amount of attributable cardiovascular (CV) mortality worldwide, and risk stratification in hypertensive patients is of crucial importance to manage treatment and prevent adverse events. Asymptomatic involvement of different organs in patients affected by HTN represents an independent determinant of CV risk and the identification of target organ damage (TOD) is recommended to further reclassify patients' risk. Non-invasive CV imaging is progressively being used and continues to provide new technological opportunities to TOD evaluation at early stage. The aim of this article is to provide the community of cardiology with an update on appropriate and justified use of non-invasive imaging tests in the growing population of hypertensive patients.

Published
2017

32. MASked-unconTrolled hypERtension management based on office BP or on ambulatory blood pressure measurement (MASTER) Study: A randomised controlled trial protocol

Author

Parati, G. Agabiti-Rosei, E. Bakris, G.L. Bilo, G. Branzi, G. Cecchi, F. Chrostowska, M. De La Sierra, A. Domenech, M. Dorobantu, M. Faria, T. Huo, Y. Jelaković, B. Kahan, T. Konradi, A. Laurent, S. Li, N. Madan, K. Mancia, G. McManus, R.J. Modesti, P.A. Ochoa, J.E. Octavio, J.A. Omboni, S. Palatini, P. Park, J.B. Pellegrini, D. Perl, S. Podoleanu, C. Pucci, G. Redon, J. Renna, N. Rhee, M.Y. Rodilla Sala, E. Sanchez, R. Schmieder, R. Soranna, D. Stergiou, G. Stojanovic, M. Tsioufis, K. Valsecchi, M.G. Veglio, F. Waisman, G.D. Wang, J.G. Wijnmaalen, P. Zambon, A. Zanchetti, A. Zhang, Y.

Abstract

Introduction Masked uncontrolled hypertension (MUCH) carries an increased risk of cardiovascular (CV) complications and can be identified through combined use of office (O) and ambulatory (A) blood pressure (BP) monitoring (M) in treated patients. However, it is still debated whether the information carried by ABPM should be considered for MUCH management. Aim of the MASked-unconTrolled hypERtension management based on OBP or on ambulatory blood pressure measurement (MASTER) Study is to assess the impact on outcome of MUCH management based on OBPM or ABPM. Methods and analysis MASTER is a 4-year prospective, randomised, open-label, blinded-endpoint investigation. A total of 1240 treated hypertensive patients from about 40 secondary care clinical centres worldwide will be included -upon confirming presence of MUCH (repeated on treatment OBP

Published
2018

33. Should renal color Doppler ultrasonography be a routine test in newly diagnosed hypertensive patient?

Author

Tsioufis, C. Andrikou, I. Pruijm, M. Ponte, B. Sarafidis, P. Koureas, A. Tousoulis, D. Agabiti-Rosei, E. Mancia, G. Burnier, M.

Abstract

European Society of Hypertension/European Society of Cardiology guidelines recommend calculation of estimated glomerular filtration rate and evaluation of urinary albumin excretion rate as routine tests in the initial evaluation and during the follow-up of all hypertensive patients. However, from a clinical point of view, renal ultrasound-a noninvasive, readily available and cheap imaging modality-could contribute to the better evaluation of a hypertensive patient by identifying common causes of secondary hypertension (HTN) originating from the kidney and more recently by detecting renal injury in severe or long-standing essential HTN by measuring renal resistive indexes. The purpose of this review is to summarize the actual evidence which could support a larger use of renal ultrasound in the work-up of patients with newly diagnosed HTN. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

Published
2018

34. 2018 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC)

Author

Williams, B. Mancia, G. Spiering, W. Agabiti Rosei, E. Azizi, M. Burnier, M. Clement, D. Coca, A. De Simone, G. Dominiczak, A. Kahan, T. Mahfoud, F. Redon, J. Ruilope, L. Zanchetti, A. Kerins, M. Kjeldsen, S. Kreutz, R. Laurent, S. Lip, G.Y.H. McManus, R. Narkiewicz, K. Ruschitzka, F. Schmieder, R. Shlyakhto, E. Tsioufis, K. Aboyans, V. Desormais, I.

Abstract

These practice guidelines on the management of arterial hypertension are a concise summary of the more extensive ones prepared by the Task Force jointly appointed by the European Society of Hypertension and the European Society of Cardiology. These guidelines have been prepared on the basis of the best available evidence on all issues deserving recommendations; their role must be educational and not prescriptive or coercive for the management of individual subjects who may differ widely in their personal, medical and cultural characteristics. The members of the Task Force have participated independently in the preparation of these guidelines, drawing on their academic and clinical experience and by objective examination and interpretation of all available literature. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.

Published
2018

35. No Longer a Sine Qua Non for Guideline Authors?

Author

Messerli, FH, Hofstetter, L, Agabiti-Rosei, E, Burnier, M, Elliott, WJ, Franklin, SS, Grodzicki, T, Kario, K, Kjeldsen, SE, Kostis, JB, Laurent, S, Leenen, FH, Lund-Johansen, P, Mancia, G, Narkiewicz, K, Papademetriou, V, Parati, G, Poulter, N, Redon, J, Rimoldi, SF, Ruilope, LM, Schiffrin, EL, Schmieder, RE, Schwartz, AB, Sever, P, Sowers, JR, Staessen, JA, Wang, J, Weber, M, and Williams, B

Subjects
OLDER, Science & Technology, HYPERTENSION, 1103 Clinical Sciences, AGED 60 YEARS, 1102 Cardiovascular Medicine And Haematology, Peripheral Vascular Disease, Cardiovascular System & Hematology, Cardiovascular System & Cardiology, BLOOD-PRESSURE TARGETS, INHIBITORS, Life Sciences & Biomedicine, METAANALYSIS, ANGIO-EDEMA
Published
2017

36. Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: A comparative risk assessment

Author

Danaei, G, Lu, Y, Singh, Gm, Carnahan, E, Stevens, Ga, Cowan, Mj, Farzadfar, F, Lin, Jk, Finucane, Mm, Rao, M, Khang, Yh, Riley, Lm, Mozaffarian, D, Lim, Ss, Ezzati, M, Aamodt, G, Abdeen, Z, Abdella, Na, Rahim, Hf, Addo, J, Aekplakorn, W, Afifi, Mm, Agabiti Rosei, E, Salinas, Ca, Agyemang, C, Ali, Mk, Ali, Mm, Al Nsour, M, Al Nuaim AR, Ambady, R, Di Angelantonio, E, Aro, P, Azizi, F, Babu, Bv, Bahalim, An, Barbagallo, Cm, Barbieri, Ma, Barceló, A, Barreto, Sm, Barros, H, Bautista, Le, Benetos, A, Bjerregaard, P, Björkelund, C, Bo, S, Bobak, M, Bonora, Enzo, Botana, Ma, Bovet, P, Breckenkamp, J, Breteler, Mm, Broda, G, Brown, Ij, Bursztyn, M, de León AC, Campos, H, Cappuccio, Fp, Capuano, V, Casiglia, E, Castellano, M, Castetbon, K, Cea, L, Chang, Cj, Chaouki, N, Chatterji, S, Chen, Cj, Chen, Z, Choi, Js, Chua, L, Cífková, R, Cobiac, Lj, Cooper, Rs, Corsi, Am, Costanza, Mc, Craig, Cl, Dankner, Rs, Dastgiri, S, Delgado, E, Dinc, G, Doi, Y, Dong, Gh, Dorsi, E, Dragano, N, Drewnowski, A, Eggertsen, R, Elliott, P, Engeland, A, Erem, C, Esteghamati, A, Fall, Ch, Fan, Jg, Ferreccio, C, Fezeu, L, Firmo, Jo, Florez, Hj, Fornés, Ns, Fowkes, Fg, Franceschini, G, Frisk, F, Fuchs, Fd, Fuller, El, Getz, L, Giampaoli, S, Gómez, Lf, Gomez Zumaquero JM, Graff Iversen, S, Grant, Jf, Carvajal, Rg, Gulliford, Mc, Gupta, R, Gupta, Pc, Gureje, O, Gutierrez, Hr, Hansen, Tw, Hata, J, He, J, Heim, N, Heinrich, J, Hemmingsson, T, Hennis, A, Herman, Wh, Herrera, Vm, Ho, S, Holdsworth, M, Frisman, Gh, Hopman, Wm, Hussain, A, Husseini, A, Ibrahim, Mm, Ikeda, N, Jacobsen, Bk, Jaddou, Hy, Jafar, Th, Janghorbani, M, Jasienska, G, Joffres, Mr, Jonas, Jb, Kadiki, Oa, Kalter Leibovici, O, Kamadjeu, Rm, Kaptoge, S, Karalis, I, Kastarinen, Mj, Katz, J, Keinan Boker, L, Kelly, P, Khalilzadeh, O, Kiechl, S, Kim, Kw, Kiyohara, Y, Kobayashi, J, Krause, Mp, Kubínová, R, Kurjata, P, Kusuma, Ys, Lam, Th, Langhammer, A, Lawes, Cm, Le, C, Lee, J, Lévy Marchal, C, Lewington, S, Li, Y, Lim, To, Lin, X, Lin, Cc, Lin, Hh, Lind, L, Lissner, L, Liu, X, Lopez Jaramillo, P, Lorbeer, R, Ma, G, Ma, S, Macià, F, Maclean, Dr, Maggi, S, Magliano, Dj, Makdisse, M, Mancia, G, Mannami, T, Marques Vidal, P, Mbanya, Jc, McFarlane Anderson, N, Miccoli, R, Miettola, J, Minh, Hv, Miquel, Jf, Miranda, Jj, Mohamed, Mk, Mohan, V, Mohanna, S, Mokdad, A, Mollentze, Wf, Morales, Dd, Morgan, K, Muiesan, Lm, Muntoni, S, Nabipour, I, Nakagami, T, Nangia, V, Nemesure, B, Neovius, M, Nerhus, Ka, Nervi, F, Neuhauser, H, Nguyen, M, Ninomiya, T, Noale, M, Oh, Sw, Ohkubo, T, Olivieri, Oliviero, Önal, Ae, Onat, A, Oróstegui, M, Ouedraogo, H, Pan, Wh, Panagiotakos, Db, Panza, F, Park, Y, Passos, Vm, Pednekar, Ms, Pelizzari, Pm, Peres, Ma, Pérez, C, Pérez Fernández, R, Pichardo, R, Phua, Hp, Pistelli, F, Plans, P, Polakowska, M, Poulter, N, Prabhakaran, D, Qiao, Q, Rafiei, M, Raitakari, Ot, Ramos, Lr, Rampal, S, Rampal, L, Rasmussen, F, Reddy, Kk, Redon, J, Revilla, L, Reyes García, V, Roaeid, Rb, Robinson, Ca, Rodriguez Artalejo, F, Rojas Martinez, R, Ronkainen, K, Rosero Bixby, L, Roth, Ga, Sachdev, Hs, Sánchez, Jr, Sanisoglu, Sy, Sans, S, Sarraf Zadegan, N, Scazufca, M, Schaan, Bd, Schapochnik, N, Schelleman, H, Schneider, Ij, Schooling, Cm, Schwarz, B, Sekuri, C, Sereday, Ms, Serra Majem, L, Shaw, J, Shera, As, Shi, Z, Shiri, R, Shu, Xo, Silva, Da, Silva, E, Simons, La, Smith, M, Söderberg, S, Soebardi, S, Solfrizzi, V, Sonestedt, E, Soysal, A, Stattin, P, Stein, Ad, Stergiou, Gs, Stessman, J, Sudo, A, Suka, M, Sundh, V, Sundquist, K, Sundström, J, Swai, Ab, Tai, Es, Tambs, K, Tesfaye, F, Thomas, Gn, Thorogood, M, Tilvis, Rs, Tobias, M, Torheim, Le, Trenkwalder, P, Tuomilehto, Jo, Tur, Ja, Tzourio, C, Uhernik, Ai, Ukoli, Fa, Unwin, N, Hoorn, Sv, Vanderpump, Mp, Varo, Jj, Veierød, Mb, Velásquez Meléndez, G, Verschuren, M, Viet, L, Villalpando, S, Vioque, J, Vollenweider, P, Volpato, S, Wang, N, Wang, Yx, Ward, M, Waspadji, S, Welin, Lx, Whitlock, G, Wilhelmsen, L, Willeit, J, Woodward, M, Wormser, 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Shi, Z, Shiri, R, Shu, X, Silva, D, Silva, E, Simons, L, Smith, M, Söderberg, S, Soebardi, S, Solfrizzi, V, Sonestedt, E, Soysal, A, Stattin, P, Stein, A, Stergiou, G, Stessman, J, Sudo, A, Suka, M, Sundh, V, Sundquist, K, Sundström, J, Swai, A, Tai, E, Tambs, K, Tesfaye, F, Thomas, G, Thorogood, M, Tilvis, R, Tobias, M, Torheim, L, Trenkwalder, P, Tuomilehto, J, Tur, J, Tzourio, C, Uhernik, A, Ukoli, F, Unwin, N, Hoorn, S, Vanderpump, M, Varo, J, Veierød, M, Velásquez-Meléndez, G, Verschuren, M, Viet, L, Villalpando, S, Vioque, J, Vollenweider, P, Volpato, S, Wang, N, Wang, Y, Ward, M, Waspadji, S, Lennart X Welin, N, Whitlock, G, Wilhelmsen, L, Willeit, J, Woodward, M, Wormser, D, André J Xavier, N, Xu, F, Xu, L, Yamamoto, A, Yang, G, Yang, X, Yeh, L, Yoon, J, You, Q, Yu, Z, Zhang, J, Zhang, L, Zheng, W, and Zhou, M

Subjects
Male, Settore MED/09 - Medicina Interna, kidney disease, Endocrinology, Diabetes and Metabolism, humanos, coste de las enfermedades, Disease, Global Health, Cohort Studies, Endocrinology, Cost of Illness, cardiovascular disease, Health Transition, Risk Factors, transición sanitaria, estudios prospectivos, Renal Insufficiency, Chronic -- complications -- epidemiology -- mortality, evaluación de riesgos, Renal Insufficiency, Prospective Studies, Chronic, estudios de cohortes, Metabolic Syndrome, education.field_of_study, diabetes, Mortality rate, Age Factors, Cardiovascular Diseases, Diabetes Complications, Female, Health Surveys, Humans, Metabolic Syndrome X, Renal Insufficiency, Chronic, Risk Assessment, Sex Factors, Spatio-Temporal Analysis, Internal Medicine, Cardiovascular Diseases -- complications -- epidemiology -- mortality, Cardiovascular disease,Diabetes Mellitus, chronic kidney disease, Diabetes Complications -- epidemiology -- mortality, Sciences bio-médicales et agricoles, Diabetes and Metabolism, encuestas de salud, análisis temporoespacial, Risk assessment, complicaciones de la diabetes, insuficiencia renal, medicine.medical_specialty, Cardiovascular disease, diabetes mortality, Population, enfermedades cardiovasculares, Metabolic Syndrome X -- complications -- epidemiology -- mortality, Article, chronic kidney disease, mortality, Internal medicine, Environmental health, Diabetes mellitus, medicine, factores de riesgo, Risk factor, education, business.industry, medicine.disease, Relative risk, Cardiovascular Diseases/complications, Cardiovascular Diseases/epidemiology, Cardiovascular Diseases/mortality, Diabetes Complications/epidemiology, Diabetes Complications/mortality, Metabolic Syndrome X/complications, Metabolic Syndrome X/epidemiology, Metabolic Syndrome X/mortality, Renal Insufficiency, Chronic/complications, Renal Insufficiency, Chronic/epidemiology, Renal Insufficiency, Chronic/mortality, business, Kidney disease
Abstract

High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010., 0, info:eu-repo/semantics/published

Published
2014

38. Erratum to: Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized 'Z' Studies (Adv Ther, (2017), 34, (784-798), 10.1007/s12325-017-0497-8)

Author

Omboni, S. Malacco, E. Napoli, C. Modesti, P.A. Manolis, A. Parati, G. Agabiti-Rosei, E. Borghi, C.

Abstract

Author wants to correct the text under the heading of Introduction. The sentence is written as: “In the ZENITH study, both treatments had a similar positive effect on regression of cardiac and renal damage, whereas a larger proportion of patients showing carotid plaque regression was observed under zofenopril (31.6% vs. 16.1%; p = 0.047), particularly in the subgroup of patients taking the low dose of zofenopril (30 mg) plus HCTZ 12.5 mg (4.7% vs 10.0% irbesartan 150 mg plus HCTZ 12.5 mg; p = 0.043)”. The correct sentence should read: “In the ZENITH study, both treatments had a similar positive effect on regression of cardiac. © 2017, The Author(s).

Published
2017

39. Who is an expert? Reply

Author

Messerli, FH, Hofstetter, L, Agabiti-Rosei, E, Burnier, M, Elliott, WJ, Franklin, SS, Grodzicki, T, Kario, K, Kjeldsen, SE, Kostis, JB, Laurent, S, Leenen, FH, De Leeuw, PW, Lund-Johansen, P, Mancia, G, Narkiewicz, K, Papademetriou, V, Parati, G, Poulter, N, Redon, J, Rimoldi, SF, Ruilope, LM, Schiffrin, EL, Schmieder, RE, Schwartz, AB, Sever, P, Sowers, JR, Staessen, JA, Wang, J, Weber, M, Williams, B, MUMC+: MA Alg Interne Geneeskunde (9), and RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience

Subjects
OLDER, Science & Technology, Peripheral Vascular Disease, Cardiovascular System & Hematology, HYPERTENSION, Cardiovascular System & Cardiology, 1103 Clinical Sciences, GUIDELINES, Life Sciences & Biomedicine, 1102 Cardiovascular Medicine And Haematology
Abstract

ispartof: Journal of Hypertension vol:35 issue:11 pages:2327-2328 ispartof: location:Netherlands status: published

Published
2017

41. Reply

Author

Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, de Leeuw PW, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, and Williams B

Published
2017

44. P464Clinic and 24 hours blood pressure values are strictly related to dimensions of the ascending aorta in a general population

Author

Salvetti, M., primary, Paini, A., additional, Bertacchini, F., additional, Stassaldi, D., additional, Agabiti Rosei, C., additional, Aggiusti, C.Q., additional, Maruelli, G., additional, Rubagotti, G., additional, Verzeri, L., additional, Sacca', G., additional, Agabiti-Rosei, E., additional, and Muiesan, M.L., additional

Published
2017
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45. Strategies for improving blood pressure control in Italy: from global cardiovascular risk stratification to combination therapy. 2012 Position paper of the Italian Society of Hypertension

Author

Volpe M, AMBROSIONI, ETTORE, BORGHI, CLAUDIO, Cottone S, Cuspidi C, De Luca N, Fallo F, Ferri C, Morganti A, Muiesan ML, Sarzani R, Sechi L, Virdis A, Tocci G, Agabiti Rosei E, Trimarco B, Filippi A, Mancia G., Volpe, M, Ambrosioni, E, Borghi, C, Cottone, S, Cuspidi, C, DE LUCA, Nicola, Fallo, F, Ferri, C, Morganti, A, Muiesan, Ml, Sarzani, R, Sechi, L, Virdis, A, Tocci, G, Agabiti Rosei, E, Trimarco, Bruno, Filippi, A, Mancia, G., Volpe M, Ambrosioni E, Borghi C, Cottone S, Cuspidi C, De Luca N, Fallo F, Ferri C, Morganti A, Muiesan ML, Sarzani R, Sechi L, Virdis A, Tocci G, Agabiti-Rosei E, Trimarco B, Filippi A, and Mancia G

Subjects
cardiovascular risk, Italy, Cardiovascular Diseases, Hypertension, Humans, ipertensione arteriosa, BLOOD PRESSURE, Combined Modality Therapy, Risk Assessment, combination therapy
Abstract

Observational studies demonstrate that the proportion of treated hypertensive patients who attain the recommended blood pressure goals (140/90 mmHg) does not exceed 30-40%. Conversely, clinical trials have consistently shown that effective blood pressure control within the recommended targets can be achieved in 70-80% of treated hypertensive patients with different cardiovascular risk profile, especially when appropriate, effective and well tolerated combination therapies are used. In order to bridge the gap between current and optimal blood pressure control rates and to achieve a more effective cardiovascular prevention, the Italian Society of Hypertension has recently developed an interventional strategy that aims to approximate 70% of treated controlled patients by 2015. This ambitious goal can be realistically achieved by the appropriate use of modern aids and tools, also including the implementation of combination therapy, especially if this approach can be simplified into a single pill, now available in Italy. At present, 70-80% of hypertensive patients require combination therapies based on at least two classes of antihypertensive drugs to achieve the recommended blood pressure goals. It is therefore of paramount importance to implement this strategy in routine clinical practice. Among the different combination therapies, the use of combination strategies based on drugs inhibiting the renin-angiotensin system, such as angiotensin receptor blockers and angiotensin-converting enzyme inhibitors, combined with diuretics and/or calcium-channel blockers, have demonstrated to significantly reduce the rates of major cardiovascular events and discontinuations from prescribed therapies, resulting in higher antihypertensive efficacy and better tolerability than monotherapy. The present document of the Italian Society of Hypertension aims to provide main indications for implementing combination therapy in the clinical management of hypertension in order to improve blood pressure control in Italy.

Published
2012

47. Excess dietary sodium and inadequate potassium intake by hypertensive patients in Italy

Author

Galletti, F, Agabiti-Rosei, E, Bernini, G, Boero, R, Desideri, G, Fallo, F, Mallamaci, F, Morganti, A, Castellano, M, Nazzaro, P, Trimarco, B, Strazzullo, P, Agabiti- Rosei, E, Campanozzi, A, Carcea, M, Donfrancesco, C, Galeone, D, Giampaoli, S, Iacoviello, L, Scalfi, L, Siani, A, Modesti, S, Parini, U, Pascale, C, Bosio, A, Cerrato, F, Pallisco, O, Massara, C, Veglio, F, Rabbia, F, Testa, E, Musso, N, Martino, S, Artom, A, Pirola, I, Parati, G, Lonati, L., Cuspidi, C, Sala, C, Rescaldani, M, Gidaro, B, Lonati, C, Grandi, A, Maresca, A, Merletti, L, Garavelli, G, Pini, C, Crippa, M, Lazzari, F, Ronchi, E, Gaudio, G, Caló, L, Caielli, P, Rossi, G, Sechi, La, Marzano, L, Catena, C, Ungar, A, Giovannetti, R, Cipollini, F, Arcangeli, E, Borgheresi, P, Panichi, V, Rossi, E, Borghi, C, Veronesi, M, Biggi, A, Musiari, L, Montanari, A, Caiazza, A, Meschi, M, Sarzani, R, Giacchetti, G, Schillaci, G, Pucci, G, Ferri, C, Mezzetti, A, Rinaldi, P., De Luca, N, Barbato, A, Fazio, V, D'Avino, M, Guglielmi, M, De Giorgi, Ga, Del Giudice, A, Belfiore, A, Barbiero, M, Murri, A, Nardecchia, A, De Pergola, G, Silvestris, F, Vinella, L, Leonardis, D, Malatino, L, Stancanelli, B, and Cilia, C.

Published
2014

48. Dose-dependent arterial destiffening and inward remodeling after olmesartan in hypertensives with metabolic syndrome

Author

Van Bortel, L, Boutouyrie, P, Laurent, S, Pannier, B, Zannad, F, Schmieder, R, Agabiti Rosei, E, Stehouwer, C, Cockcroft, J, Wilkinson, I., GIANNATTASIO, CRISTINA, MANCIA, GIUSEPPE, Van Bortel, L, Boutouyrie, P, Laurent, S, Pannier, B, Zannad, F, Schmieder, R, Agabiti Rosei, E, Giannattasio, C, Mancia, G, Stehouwer, C, Cockcroft, J, Wilkinson, I, MUMC+: HVC Pieken Maastricht Studie (9), Interne Geneeskunde, MUMC+: MA Interne Geneeskunde (3), and RS: CARIM - R3 - Vascular biology

Subjects
medicine.medical_specialty, hypertension, Carotid arteries, compliance, arteries, Internal medicine, medicine.artery, Internal Medicine, medicine, Pulse wave velocity, Aorta, business.industry, blood pressure, arterie, antihypertensive agents, medicine.disease, Compliance (physiology), aorta, Blood pressure, Endocrinology, randomized controlled trial, Cardiology, antihypertensive agent, Aortic stiffness, Metabolic syndrome, business, Olmesartan, medicine.drug
Abstract

Whether angiotensin receptor blockers can dose-dependently remodel the arterial wall during long-term treatment has been largely debated. In this phase III, multicenter, randomized, double-blind, parallel-group study, 133 subjects with hypertension and metabolic syndrome were assigned to olmesartan, either 20 mg (n=44), 40 mg (n=42), or 80 mg (n=47) once a day, according to a force titration design during a 1-year period. Office blood pressure, 24-hour blood pressure, aortic stiffness (carotid-femoral pulse wave velocity), and carotid parameters were measured at baseline, 24 weeks, and 52 weeks. Pulse wave velocity significantly decreased ( P P =0.0685) for a smaller effect of 20 mg, compared with 40 and 80 mg at week 52. When the 40 and 80 mg doses were combined (40/80 mg versus 20 mg), a significant blood pressure–independent reduction in pulse wave velocity (−0.61 m/s) was observed at week 52 ( P =0.0066), whereas the nonadjusted reduction was −1.31 m/s ( P

Published
2014

50. A smartphone device for ocular fundus photography in acute hypertension

Author

Muiesan, M. L., Salvetti, M., Riviera, M., Pintossi, C., Bertacchini, F., Colonetti, E., Paini, A., Poli, M., Semeraro, F., Agabiti Rosei, E., and Russo, A.

Subjects
smartphone, D-Eye, acute hypertension, opthalmoscopy, opthalmoscopy, smartphone, D-Eye, acute hypertension
Published
2016

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