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1. Cardiovascular Outcomes in GRADE (Glycemia Reduction Approaches in Type 2 Diabetes: A Comparative Effectiveness Study)

Author

Green, Jennifer B., Everett, Brendan M., Ghosh, Alokananda, Younes, Naji, Krause-Steinrauf, Heidi, Barzilay, Joshua, Desouza, Cyrus, Inzucchi, Silvio E., Pokharel, Yashashwi, Schade, David, Scrymgeour, Alexandra, Tan, Meng H., Utzschneider, Kristina M., Mudaliar, Sunder, Crandall, J.P., McKee, M.D., Behringer-Massera, S., Brown-Friday, J., Xhori, E., Ballentine-Cargill, K., Duran, S., Estrella, H., Gonzalez de la Torre, S., Lukin, J., Phillips, L.S., Burgess, E., Olson, D., Rhee, M., Wilson, P., Raines, T.S., Boers, J., Costello, J., Maher-Albertelli, M., Mungara, R., Savoye, L., White, C.A., Gullett, C., Holloway, L., Morehead, F., Person, S., Sibymon, M., Tanukonda, S., Adams, C., Ross, A., Balasubramanyam, A., Gaba, R., Gonzalez Hattery, E., Ideozu, A., Jimenez, J., Montes, G., Wright, C., Hollander, P., Roe, E., Jackson, A., Smiley, A., Burt, P., Estrada, L., Chionh, K., Ismail-Beigi, F., Falck-Ytter, C., Sayyed Kassem, L., Sood, A., Tiktin, M., Kulow, T., Newman, C., Stancil, K.A., Cramer, B., Iacoboni, J., Kononets, M.V., Sanders, C., Tucker, L., Werner, A., Maxwell, A., McPhee, G., Patel, C., Colosimo, L., Krol, A., Goland, R., Pring, J., Alfano, L., Kringas, P., Hausheer, C., Tejada, J., Gumpel, K., Kirpitch, A., Schneier, H., AbouAssi, H., Chatterjee, R., Feinglos, M.N., English Jones, J., Khan, S.A., Kimpel, J.B., Zimmer, R.P., Furst, M., Satterwhite, B.M., Thacker, C.R., Evans Kreider, K., Mariash, C.N., Mather, K.J., Ismail, H.M., Lteif, A., Mullen, M., Hamilton, T., Patel, N., Riera, G., Jackson, M., Pirics, V., Aguillar, D., Howard, D., Hurt, S., Bergenstal, R., Carlson, A., Martens, T., Johnson, M., Hill, R., Hyatt, J., Jensen, C., Madden, M., Martin, D., Willis, H., Konerza, W., Yang, S., Kleeberger, K., Passi, R., Fortmann, S., Herson, M., Mularski, K., Glauber, H., Prihoda, J., Ash, B., Carlson, C., Ramey, P.A., Schield, E., Torgrimson-Ojerio, B., Arnold, K., Kauffman, B., Panos, E., Sahnow, S., Bays, K., Berame, K., Cook, J., Ghioni, D., Gluth, J., Schell, K., Criscola, J., Friason, C., Jones, S., Nazarov, S., Rassouli, N., Puttnam, R., Ojoawo, B., Nelson, R., Curtis, M., Hollis, B., Sanders-Jones, C., Stokes, K., El-Haqq, Z., Kolli, A., Tran, T., Wexler, D., Larkin, M.E., Meigs, J., Chambers, B., Dushkin, A., Rocchio, G., Yepes, M., Steiner, B., Dulin, H., Cayford, M., Chu, K., DeManbey, A., Hillard, M., Martin, K., Thangthaeng, N., Gurry, L., Kochis, R., Raymond, E., Ripley, V., Stevens, C., Park, J., Aroda, V., Ghazi, A., Magee, M., Ressing, A., Loveland, A., Hamm, M., Hurtado, M., Kuhn, A., Leger, J., Manandhar, L., Mwicigi, F., Sanchez, O., Young, T., Garg, R., Lagari-Libhaber, V., Florez, H.J., Valencia, W.M., Marks, J., Casula, S., Oropesa-Gonzalez, L., Hue, L., Cuadot, A., Nieto-Martinez, R., Riccio Veliz, A.K., Gutt, M., Kendal, Y.J., Veciana, B., Ahmann, A., Aby-Daniel, D., Joarder, F., Morimoto, V., Sprague, C., Yamashita, D., Cady, N., Rivera-Eschright, N., Kirchhoff, P., Morales Gomez, B., Adducci, J., Goncharova, A., Hox, S.H., Petrovitch, H., Matwichyna, M., Jenkins, V., Broadwater, L., Ishii, R.R., Bermudez, N.O., Hsia, D.S., Cefalu, W.T., Greenway, F.L., Waguespack, C., King, E., Fry, G., Dragg, A., Gildersleeve, B., Arceneaux, J., Haynes, N., Thomassie, A., Pavlionis, M., Bourgeois, B., Hazlett, C., Henry, R., Boeder, S., Pettus, J., Diaz, E., Garcia-Acosta, D., Maggs, S., DeLue, C., Stallings, A., Castro, E., Hernandez, S., Krakoff, J., Curtis, J.M., Killean, T., Khalid, M., Joshevama, E., Diaz, E., Martin, D., Tsingine, K., Karshner, T., Albu, J., Pi-Sunyer, F.X., Frances, S., Maggio, C., Ellis, E., Bastawrose, J., Gong, X., Banerji, M.A., August, P., Lee, M., Lorber, D., Brown, N.M., Josephson, D.H., Thomas, L.L., Tsovian, M., Cherian, A., Jacobson, M.H., Mishko, M.M., Kirkman, M.S., Buse, J.B., Diner, J., Dostou, J., Machineni, S., Young, L., Bergamo, K., Goley, A., Kerr, J., Largay, J.F., Guarda, S., Cuffee, J., Culmer, D., Fraser, R., Almeida, H., Coffer, S., Debnam, E., Kiker, L., Morton, S., Josey, K., Fuller, G., Garvey, W.T., Cherrington, A.L., Dyer, D., Lawson, M.C.R., Griffith, O., Agne, A., McCullars, S., Cohen, R.M., Craig, J., Rogge, M.C., Burton, K., Kersey, K., Wilson, C., Lipp, S., Vonder Meulen, M.B., Adkins, C., Onadeko, T., Rasouli, N., Baker, C., Schroeder, E., Razzaghi, M., Lyon, C., Penaloza, R., Underkofler, C., Lorch, R., Douglass, S., Steiner, S., Sivitz, W.I., Cline, E., Knosp, L.K., McConnell, J., Lowe, T., Herman, W.H., Pop-Busui, R., Martin, C., Waltje, A., Katona, A., Goodhall, L., Eggleston, R., Kuo, S., Bojescu, S., Bule, S., Kessler, N., LaSalle, E., Whitley, K., Seaquist, E.R., Bantle, A., Harindhanavudhi, T., Kumar, A., Redmon, B., Bantle, J., Coe, M., Mech, M., Taddese, A., Lesne, L., Smith, S., Kuechenmeister, L., Shivaswamy, V., Burbach, S., Rodriguez, M.G., Seipel, K., Alfred, A., Morales, A.L., Eggert, J., Lord, G., Taylor, W., Tillson, R., Adolphe, A., Burge, M., Duran-Valdez, E., Martinez, J., Bancroft, A., Kunkel, S., Ali Jamaleddin Ahmad, F., Hernandez McGinnis, D., Pucchetti, B., Scripsick, E., Zamorano, A., DeFronzo, R.A., Cersosimo, E., Abdul-Ghani, M., Triplitt, C., Juarez, D., Mullen, M., Garza, R.I., Verastiqui, H., Wright, K., Puckett, C., Raskin, P., Rhee, C., Abraham, S., Jordan, L.F., Sao, S., Morton, L., Smith, O., Osornio Walker, L., Schnurr-Breen, L., Ayala, R., Kreymer, R.B., Sturgess, D., Kahn, S.E., Alarcon-Casas Wright, L., Boyko, E.J., Tsai, E.C., Trence, D.L., Trikudanathan, S., Fattaleh, B.N., Montgomery, B.K., Atkinson, K.M., Kozedub, A., Concepcion, T., Moak, C., Prikhodko, N., Rhothisen, S., Elasy, T.A., Martin, S., Shackelford, L., Goidel, R., Hinkle, N., Lovell, C., Myers, J., Lipps Hogan, J., McGill, J.B., Salam, M., Schweiger, T., Kissel, S., Recklein, C., Clifton, M.J., Tamborlane, W., Camp, A., Gulanski, B., Pham, K., Alguard, M., Gatcomb, P., Lessard, K., Perez, M., Iannone, L., Magenheimer, E., Montosa, A., Cefalu, W.T., Fradkin, J., Burch, H.B., Bremer, A.A., Nathan, D.M., Lachin, J.M., Buse, J.B., Kahn, S.E., Larkin, M.E., Tiktin, M., Wexler, D., Burch, H.B., Bremer, A.A., Lachin, J.M., Bebu, I., Butera, N., Buys, C.J., Fagan, A., Gao, Y., Gramzinski, M.R., Hall, S.D., Kazemi, E., Legowski, E., Liu, H., Suratt, C., Tripputi, M., Arey, A., Backman, M., Bethepu, J., Lund, C., Mangat Dhaliwal, P., McGee, P., Mesimer, E., Ngo, L., Steffes, M., Seegmiller, J., Saenger, A., Arends, V., Gabrielson, D., Conner, T., Warren, S., Day, J., Huminik, J., Soliman, E.Z., Zhang, Z.M., Campbell, C., Hu, J., Keasler, L., Hensley, S., Li, Y., Herman, W.H., Kuo, S., Martin, C., Waltje, A., Mihalcea, R., Min, D.J., Perez-Rosas, V., Prosser, L., Resnicow, K., Ye, W., Shao, H., Zhang, P., Luchsinger, J., Sanchez, D., Assuras, S., Groessl, E., Sakha, F., Chong, H., Hillery, N., Abdouch, I., Bahtiyar, G., Brantley, P., Broyles, F.E., Canaris, G., Copeland, P., Craine, J.J., Fein, W.L., Gliwa, A., Hope, L., Lee, M.S., Meiners, R., Meiners, V., O’Neal, H., Park, J.E., Sacerdote, A., Sledge Jr, E., Soni, L., Steppel-Reznik, J., and Turchin, A.

Published
2024
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2. A Prepaid Energy Billing System with Credit Shortage Forecasting

Author

Abdul Ghani, M. F. F., Mohd Yusoff, M. A. F., Wong, H. L., Yip, S. C., Tan, C. K., Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Alfred, Rayner, editor, and Lim, Yuto, editor

Published
2022
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4. Clinical and Metabolic Characterization of Adults With Type 2 Diabetes by Age in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) Cohort

Author

Aroda, Vanita R., Krause-Steinrauf, Heidi, Kazemi, Erin J., Buse, John B., Gulanski, Barbara I., Florez, Hermes J., Ahmann, Andrew J., Loveland, Amy, Kuhn, Alexander, Lonier, Jacqueline Y., Wexler, Deborah J., Crandall, J.P., McKee, M.D., Behringer-Massera, S., Brown-Friday, J., Xhori, E., Ballentine-Cargill, K., Duran, S., Estrella, H., Gonzalez de la torre, S., Lukin, J., Phillips, L.S., Burgess, E., Olson, D., Rhee, M., Wilson, P., Raines, T.S., Boers, J., Costello, J., Maher-Albertelli, M., Mungara, R., Savoye, L., White, C.A., Gullett, C., Holloway, L., Morehead, F., Person, S., Sibymon, M., Tanukonda, S., Adams, C., Ross, A., Balasubramanyam, A., Gaba, R., Gonzalez Hattery, E., Ideozu, A., Jimenez, J., Montes, G., Wright, C., Hollander, P., Roe, E., Jackson, A., Smiley, A., Burt, P., Estrada, L., Chionh, K., Ismail-Beigi, F., Falck-Ytter, C., Sayyed Kassem, L., Sood, A., Tiktin, M., Kulow, T., Newman, C., Stancil, K.A., Cramer, B., Iacoboni, J., Kononets, M.V., Sanders, C., Tucker, L., Werner, A., Maxwell, A., McPhee, G., Patel, C., Colosimo, L., Krol, A., Goland, R., Pring, J., Alfano, L., Kringas, P., Hausheer, C., Tejada, J., Gumpel, K., Kirpitch, A., Schneier, H., Green, J.B., AbouAssi, H., Chatterjee, R., Feinglos, M.N., English Jones, J., Khan, S.A., Kimpel, J.B., Zimmer, R.P., Furst, M., Satterwhite, B.M., Thacker, C.R., Evans Kreider, K., Mariash, C.N., Mather, K.J., Ismail, H.M., Lteif, A., Mullen, M., Hamilton, T., Patel, N., Riera, G., Jackson, M., Pirics, V., Aguillar, D., Howard, D., Hurt, S., Bergenstal, R., Carlson, A., Martens, T., Johnson, M., Hill, R., Hyatt, J., Jensen, C., Madden, M., Martin, D., Willis, H., Konerza, W., Yang, S., Kleeberger, K., Passi, R., Fortmann, S., Herson, M., Mularski, K., Glauber, H., Prihoda, J., Ash, B., Carlson, C., Ramey, P.A., Schield, E., Torgrimson-Ojerio, B., Arnold, K., Kauffman, B., Panos, E., Sahnow, S., Bays, K., Berame, K., Cook, J., Ghioni, D., Gluth, J., Schell, K., Criscola, J., Friason, C., Jones, S., Nazarov, S., Barzilay, J., Rassouli, N., Puttnam, R., Ojoawo, B., Nelson, R., Curtis, M., Hollis, B., Sanders-Jones, C., Stokes, K., El-Haqq, Z., Kolli, A., Tran, T., Wexler, D., Larkin, M., Meigs, J., Chambers, B., Dushkin, A., Rocchio, G., Yepes, M., Steiner, B., Dulin, H., Cayford, M., Chu, K., DeManbey, A., Hillard, M., Martin, K., Thangthaeng, N., Gurry, L., Kochis, R., Raymond, E., Ripley, V., Stevens, C., Park, J., Aroda, V., Ghazi, A., Magee, M., Ressing, Ann, Loveland, A., Hamm, M., Hurtado, M., Kuhn, A., Leger, J., Manandhar, L., Sanchez, O., Young, T., Mofor, F., Garg, R., Lagari-Libhaber, V., Florez, H.J., Valencia, W.M., Marks, J., Casula, S., Oropesa-Gonzalez, L., Hue, L., Cuadot, A., Nieto-Martinez, R., Riccio Veliz, A.K., Gutt, M., Kendal, Y.J., Veciana, B., Ahmann, A., Aby-Daniel, D., Joarder, F., Morimoto, V., Sprague, C., Yamashita, D., Cady, N., Rivera-Eschright, N., Kirchhoff, P., Morales Gomez, B., Adducci, J., Goncharova, A., Hox, S.H., Petrovitch, H., Matwichyna, M., Jenkins, V., Broadwater, L., Ishii, R.R., Bermudez, N.O., Hsia, D.S., Cefalu, W.T., Greenway, F.L., Waguespack, C., King, E., Fry, G., Dragg, A., Gildersleeve, B., Arceneaux, J., Haynes, N., Thomassie, A., Pavlionis, M., Bourgeois, B., Hazlett, C., Mudaliar, S., Henry, R., Boeder, S., Pettus, J., Diaz, E., Garcia-Acosta, D., Maggs, S., DeLue, C., Stallings, A., Castro, E., Hernandez, S., Krakoff, J., Curtis, J.M., Killean, T., Khalid, M., Joshevama, E., Tsingine, K., Karshner, T., Albu, J., Pi-Sunyer, F.X., Frances, S., Maggio, C., Ellis, E., Bastawrose, J., Gong, X., Banerji, M.A., August, P., Lee, M., Lorber, D., Brown, N.M., Josephson, D.H., Thomas, L.L., Tsovian, M., Cherian, A., Jacobson, M.H., Mishko, M.M., Kirkman, M.S., Buse, J.B., Dostou, J., Machineni, S., Young, L., Bergamo, K., Goley, A., Kerr, J., Largay, J.F., Guarda, S., Cuffee, J., Culmer, D., Fraser, R., Almeida, H., Coffer, S., Debnam, E., Kiker, L., Morton, S., Josey, K., Fuller, G., Garvey, W.T., Cherrington, A.L., Dyer, D., Lawson, M.C.R., Griffith, O., Agne, A., McCullars, S., Cohen, R.M., Craig, J., Rogge, M.C., Burton, K., Kersey, K., Wilson, C., Lipp, S., Vonder Meulen, M.B., Adkins, C., Onadeko, T., Rasouli, N., Baker, C., Schroeder, E., Razzaghi, M., Lyon, C., Penaloza, R., Underkofler, C., Lorch, R., Douglass, S., Steiner, S., Sivitz, W.I., Cline, E., Knosp, L.K., McConnell, J., Lowe, T., Herman, W.H., Pop-Busui, R., Tan, M.H., Martin, C., Waltje, A., Katona, A., Goodhall, L., Eggleston, R., Kuo, S., Bojescu, S., Bule, S., Kessler, N., LaSalle, E., Whitley, K., Seaquist, E.R., Bantle, A., Harindhanavudhi, T., Kumar, A., Redmon, B., Bantle, J., Coe, M., Mech, M., Taddese, A., Lesne, L., Smith, S., Desouza, C., Kuechenmeister, L., Shivaswamy, V., Burbach, S., Rodriguez, M.G., Seipel, K., Alfred, A., Morales, A.L., Eggert, J., Lord, G., Taylor, W., Tillson, R., Schade, D.S., Adolphe, A., Burge, M., Duran-Valdez, E., Martinez, J., Bancroft, A., Kunkel, S., Ali Jamaleddin Ahmad, F., Hernandez McGinnis, D., Pucchetti, B., Scripsick, E., Zamorano, A., DeFronzo, R.A., Cersosimo, E., Abdul-Ghani, M., Triplitt, C., Juarez, D., Garza, R.I., Verastiqui, H., Wright, K., Puckett, C., Raskin, P., Rhee, C., Abraham, S., Jordan, L.F., Sao, S., Morton, L., Smith, O., Osornio Walker, L., Schnurr-Breen, L., Ayala, R., Kreymer, R.B., Sturgess, D., Utzschneider, K.M., Kahn, S.E., Alarcon-Casas, L., Wright, L., Boyko, E.J., Tsai, E.C., Trence, D.L., Trikudanathan, S., Fattaleh, B.N., Montgomery, B.K., Atkinson, K.M., Kozedub, A., Concepcion, T., Moak, C., Prikhodko, N., Rhothisen, S., Elasy, T.A., Martin, S., Shackelford, L., Goidel, R., Hinkle, N., Lovell, C., Myers, J., Lipps Hogan, J., McGill, J.B., Salam, M., Schweiger, T., Kissel, S., Recklein, C., Clifton, M.J., Tamborlane, W., Camp, A., Gulanski, B., Inzucchi, S.E., Pham, K., Alguard, M., Gatcomb, P., Lessard, K., Perez, M., Iannone, L., Magenheimer, E., Montosa, A., Burch, H.B., Bremer, A.A., Fradkin, J., Nathan, D.M., Lachin, J.M., Krause-Steinrauf, H., Younes, N., Backman, M., Bebu, I., Butera, N., Buys, C.J., Fagan Murphy, A., Gao, Y., Ghosh, A., Gramzinski, M.R., Kazemi, E., Hall, S.D., Legowski, E., Suratt, C., Tripputi, M., Arey, A., Bethepu, J., Lund, C., Mangat Dhaliwal, P., McGee, P., Mesimer, E., Ngo, L., Steffes, M., Seegmiller, J., Saenger, A., Arends, V., Gabrielson, D., Conner, T., Warren, S., Day, J., Huminik, J., Scrymgeour, A., Soliman, E.Z., Pokharel, Y., Zhang, Z.M., Campbell, C., Hu, J., Keasler, L., Hensley, S., Li, Y., Mihalcea, R., Min, D.J., Perez-Rosas, V., Prosser, L., Resnicow, K., Ye, W., Shao, H., Zhang, P., Luchsinger, J., Sanchez, D., Assuras, S., Groessl, E., Sakha, F., Chong, H., Hillery, N., Everett, B.M., Abdouch, I., Bahtiyar, G., Brantley, P., Broyles, F.E., Canaris, G., Copeland, P., Craine, J.J., Fein, W.L., Gliwa, A., Hope, L., Lee, M.S., Meiners, R., Meiners, V., O’Neal, H., Park, J.E., Sacerdote, A., Sledge, E., Soni, L., Steppel-Reznik, J., Turchin, A., Brooks-Worrell, B., Hampe, C.S., Newgard, C.B., Palmer, J.P., Shojaie, A., Higgins, J., Fischer, L., Golden, S., Gonzalez, J., Naik, A., Walker, E., Doner Lotenberg, L., Gallivan, J.M., Lim, J., and Tuncer, D.M.

Subjects
Clinical Care/Education/Nutrition/Psychosocial Research
Abstract

OBJECTIVE: Differences in type 2 diabetes phenotype by age are described, but it is not known whether these differences are seen in a more uniformly defined adult population at a common early stage of care. We sought to characterize age-related clinical and metabolic characteristics of adults with type 2 diabetes on metformin monotherapy, prior to treatment intensification. RESEARCH DESIGN AND METHODS: In the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE), participants were enrolled who had type 2 diabetes duration

Published
2022

5. Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients

Author

Cakirca M, Karatoprak C, Zorlu M, Kiskac M, Kanat M, Cikrikcioglu MA, Soysal P, Hursitoglu M, Camli AA, Erkoc R, and Abdul-Ghani M

Subjects
Therapeutics. Pharmacology, RM1-950
Abstract

Mustafa Cakirca,1 Cumali Karatoprak,1 Mehmet Zorlu,1 Muharrem Kiskac,1 Mustafa Kanat,2 Mehmet Ali Cikrikcioglu,1 Pinar Soysal,3 Mehmet Hursitoglu,4 Ahmet Adil Camli,1 Reha Erkoc,1 Muhammad Abdul-Ghani5 1Internal Medicine Clinic, Faculty of Medicine, Bezmialem Vakif University, 2Department of Internal Medicine, Medical Faculty, Istanbul Medipol University, 3Department of Geriatric Medicine, Medical Faculty, Dokuz Eylül University, 4Department of Internal Medicine, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey; 5Division of Medicine – Diabetes, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA Aims: A close association has been demonstrated between increased cardiovascular risk and high asymmetric dimethylarginine (ADMA) levels in type 2 diabetes mellitus (DM) patients. We planned to measure serum ADMA levels in type 2 DM patients using vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. Materials and methods: A total of 68 type 2 DM patients who were on metformin were enrolled in the study. Based on the glycemic levels of patients, vildagliptin was added on to treatment in 33 patients. Patients were followed for 6 months. Serum ADMA, C-reactive protein, and fibrinogen levels were compared in groups of patients using metformin or metformin + vildagliptin, after 6 months. Results: Serum ADMA levels were found to be significantly lower in the group using vildagliptin compared to the group using metformin + vildagliptin (P

Published
2014

6. A Randomised Crossover Trial: Exploring the Dose-Response effect Of Carbohydrate restriction on glycaemia in people with well-controlled type 2 diabetes (D-ROC2)

Author

Al Ozairi, E., Al Awadi, R., El Samad, A., Taghadom, E., Al-Kandari, J., Abdul-Ghani, M., Oliver, N., Whitcher, B., and Guess, N.

Abstract

Aims Trials investigating the role of carbohydrate restriction in the management of glycaemia in type 2 diabetes (T2D) have been confounded by multiple factors including degree of calorie restriction, dietary protein content, and by no clear definition of a low-carbohydrate diet. The current study sought to provide insight into the relationship between carbohydrate restriction and glycaemia by testing the effect of varying doses of carbohydrate on continuous glucose concentrations within a range of intakes defined as low-carbohydrate while controlling for confounding factors. Methods This was a randomised crossover trial in participants with T2D (HbA1c: 6.6 ± 0.6%, 49 ± 0.9 mmol/mol) testing 5 different 6-day eucaloric dietary treatments with varying carbohydrate content (10%, 15%, 20%, 25%, and 30% kcal). Diets exchanged %kcal from carbohydrate with fat, keeping protein constant at 15% kcal. Daily self-weighing was employed to ensure weight stability throughout each treatment arm. Between dietary treatments, participants underwent a washout period of at least 7 days and were advised to maintain their habitual diet. Glycaemic control was assessed using a continuous glucose monitoring device. Results 12 participants completed the study. There were no differences in 24-hour and postprandial sensor glucose concentrations between the 30%kcal and 10%kcal doses (7.4 ± 1.1mmol/L vs 7.6 ± 1.3mmol/L (P=0.28) and 8.1 ± 1.5mmol/L vs 8.5 ± 1.4mmol/L (P=0.28) respectively). In our exploratory analyses we did not find any dose-response relationship between carbohydrate intake and glycaemia. A small amount of weight loss occurred in each treatment arm (range: 0.4 to 1.1kg over the 6 days) but adjusting for these differences did not influence the primary or secondary outcomes. Conclusions Modest changes in dietary carbohydrate content in the absence of weight loss while keeping dietary protein intake constant do not appear to influence glucose concentrations in people with well-controlled T2D.

Published
2022
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10. A Randomised Crossover Trial: Exploring the Dose-Response effect Of Carbohydrate restriction on glycaemia in people with type 2 diabetes (D-ROC2)

Author

Al-Kandari J, Awadi Ra, Ozairi Ea, Brandon Whitcher, Guess N, Abdul-Ghani M, Nick Oliver, Samad Ae, and Taghadom E

Subjects
Normal diet, business.industry, Unsaturated fat, Calorie restriction, Type 2 diabetes, medicine.disease, Crossover study, chemistry.chemical_compound, Animal science, Postprandial, chemistry, Weight loss, medicine, medicine.symptom, business, Glycemic
Abstract

AimsThe role of carbohydrate restriction in the management of glycaemia in type 2 diabetes (T2D) has been a subject of immense debate and controversy partly due to low-carbohydrate trials being confounded by multiple factors including degree of calorie restriction, dietary protein content, and by no clear definition of a low-carbohydrate diet. The current study sought to provide insight into the relationship between carbohydrate restriction and glycaemia by testing the effect of varying doses of carbohydrate on continuous glucose concentrations within a range of intakes defined as low-carbohydrate while controlling for confounding factors.MethodsThis was a randomised crossover trial in participants with T2D testing 5 different 6-day eucaloric, isocaloric dietary treatments with varying carbohydrate contents (10%, 15%, 20%, 25%, and 30% kcal). Diets were kept isocaloric by exchanging %kcal from carbohydrate with predominantly unsaturated fat, keeping protein constant at 15% kcal. Daily self-weighing was employed to ensure participants maintained their weight throughout each treatment arm. Between dietary treatments, participants underwent a washout period of at least 7 days and were advised to maintain their habitual diet. Glycemic control was assessed using a continuous glucose monitoring device that was placed while the participant was on their normal diet, and was worn for the 6 days of each treatment.Results12 participants completed the study. There were no differences in 24-hour and postprandial sensor glucose concentrations between the 30%kcal and 10%kcal doses (7.4 ± 1.1mmol/L vs 7.6 ± 1.4mmol/L (P=0.28) and 8.0 ± 1.4mmol/L vs 8.3 ± 1.3mmol/L (P=0.28) respectively). In our exploratory analyses we did not find any dose-response relationship between carbohydrate intake and glycaemia. A small amount of weight loss occurred in each treatment arm (range: 0.4 to 1.1kg over the 6 days) but adjusting for these differences did not influence the primary or secondary outcomes.ConclusionsModest changes in dietary carbohydrate content in the absence of weight loss while keeping dietary protein intake constant do not appear to influence glucose concentrations in people with T2D.Trial RegistrationISRCTN 11067343.

Published
2021
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11. Insulin Secretion is a Strong Predictor for Need of Insulin Therapy in Patients With New Onset Diabetes and HbA1c >10%, a post hoc analysis of EDICT study

Author

Abdelgani, S, Puckett, C, Adams, J, Triplitt, C, DeFronzo, RA, and Abdul-Ghani, M

Subjects
Blood Glucose, Glycated Hemoglobin, endocrine system diseases, Diabetes Mellitus, Type 2, Insulin Secretion, nutritional and metabolic diseases, Humans, Hypoglycemic Agents, Insulin, Article
Abstract

AIM: to identify predictors of response to glucose lowering therapy in patients with new onset diabetes and very high HbA1c (>10%). RESEARCH DESIGN AND METHODS: the study included EDICT participants with initial HbA1c >10% (N=104). All subjects received a 75-gram OGTT before initiation of therapy, and then were randomized to receive: (i) initial Triple Therapy with metformin, pioglitazone, and exenatide versus (ii) stepwise Conventional Therapy with metformin followed by glipizide and then glargine insulin to reduce A1c < 6.5%. Insulin secretion and insulin resistance were calculated with OGTT-derived indices RESULTS: 61% of participants in the Conventional Therapy group achieved HbA1c 1.7 predicted subjects who achieved the treatment target without insulin irrespective of the FPG concentration and whether or not they were started on Conventional or Triple Therapy. Subjects with CPEP(120)/CPEP(0) 10%.

Published
2021

15. Accuracy of 1-hour plasma glucose during the oral glucose tolerance test in diagnosis of type 2 diabetes in adults:a meta-analysis

Author

Ahuja, V. (Vasudha), Aronen, P. (Pasi), Pramodkumar, T. A. (T. A.), Looker, H. (Helen), Chetrit, A. (Angela), Bloigu, A. H. (Aini H.), Juutilainen, A. (Auni), Bianchi, C. (Cristina), La Sala, L. (Lucia), Anjana, R. M. (Ranjit Mohan), Pradeepa, R. (Rajendra), Venkatesan, U. (Ulagamadesan), Jebarani, S. (Sarvanan), Baskar, V. (Viswanathan), Fiorentino, T. V. (Teresa Vanessa), Timpel, P. (Patrick), DeFronzo, R. A. (Ralph A.), Ceriello, A. (Antonio), Del Prato, S. (Stefano), Abdul-Ghani, M. (Muhammad), Keinänen-Kiukaanniemi, S. (Sirkka), Dankner, R. (Rachel), Bennett, P. H. (Peter H.), Knowler, W. C. (William C.), Schwarz, P. (Peter), Sesti, G. (Giorgio), Oka, R. (Rie), Mohan, V. (Viswanathan), Groop, L. (Leif), Tuomilehto, J. (Jaakko), Ripatti, S. (Samuli), Bergman, M. (Michael), Tuomi, T. (Tiinamaija), Ahuja, V. (Vasudha), Aronen, P. (Pasi), Pramodkumar, T. A. (T. A.), Looker, H. (Helen), Chetrit, A. (Angela), Bloigu, A. H. (Aini H.), Juutilainen, A. (Auni), Bianchi, C. (Cristina), La Sala, L. (Lucia), Anjana, R. M. (Ranjit Mohan), Pradeepa, R. (Rajendra), Venkatesan, U. (Ulagamadesan), Jebarani, S. (Sarvanan), Baskar, V. (Viswanathan), Fiorentino, T. V. (Teresa Vanessa), Timpel, P. (Patrick), DeFronzo, R. A. (Ralph A.), Ceriello, A. (Antonio), Del Prato, S. (Stefano), Abdul-Ghani, M. (Muhammad), Keinänen-Kiukaanniemi, S. (Sirkka), Dankner, R. (Rachel), Bennett, P. H. (Peter H.), Knowler, W. C. (William C.), Schwarz, P. (Peter), Sesti, G. (Giorgio), Oka, R. (Rie), Mohan, V. (Viswanathan), Groop, L. (Leif), Tuomilehto, J. (Jaakko), Ripatti, S. (Samuli), Bergman, M. (Michael), and Tuomi, T. (Tiinamaija)

Abstract

Objective: One-hour plasma glucose (1-h PG) during the oral glucose tolerance test (OGTT) is an accurate predictor of type 2 diabetes. We performed a meta-analysis to determine the optimum cutoff of 1-h PG for detection of type 2 diabetes using 2-h PG as the gold standard. Research design and methods: We included 15 studies with 35,551 participants from multiple ethnic groups (53.8% Caucasian) and 2,705 newly detected cases of diabetes based on 2-h PG during OGTT. We excluded cases identified only by elevated fasting plasma glucose and/or HbA1c. We determined the optimal 1-h PG threshold and its accuracy at this cutoff for detection of diabetes (2-h PG ≥11.1 mmol/L) using a mixed linear effects regression model with different weights to sensitivity/specificity (2/3, 1/2, and 1/3). Results: Three cutoffs of 1-h PG, at 10.6 mmol/L, 11.6 mmol/L, and 12.5 mmol/L, had sensitivities of 0.95, 0.92, and 0.87 and specificities of 0.86, 0.91, and 0.94 at weights 2/3, 1/2, and 1/3, respectively. The cutoff of 11.6 mmol/L (95% CI 10.6, 12.6) had a sensitivity of 0.92 (0.87, 0.95), specificity of 0.91 (0.88, 0.93), area under the curve 0.939 (95% confidence region for sensitivity at a given specificity: 0.904, 0.946), and a positive predictive value of 45%. Conclusions: The 1-h PG of ≥11.6 mmol/L during OGTT has a good sensitivity and specificity for detecting type 2 diabetes. Prescreening with a diabetes-specific risk calculator to identify high-risk individuals is suggested to decrease the proportion of false-positive cases. Studies including other ethnic groups and assessing complication risk are warranted.

Published
2021

21. A trial Of Immunisation Against Cutaneous Leishmaniasis

Author

Mohammed A. Kadir, Hussein S.A. Al-Obaidi, Ghanim A. Al-hula, and Abdul-Ghani M. AI-Samarai

Subjects
Medicine, Medicine (General), R5-920
Abstract

Background: Cutaneous leishmaniasis is an endemic protozoal disease in Iraq. Recovery from the disease confers a solid and permanent immunity. Vaccination with a living inoculum of promastigotes isolated from culture reduce the incidence of disease. Objective: To show the efficacy of different types of antigens for protection of Balb/c mice against cutaneous leishmaniasis. Methods: Thirty Balb Ic mice were divided in to six groups, groups 1-4 were immunized with different types of antigens (heat killed, freezing-thawing, formalin fixed and ultrasonicated). Received June 2005 Group 5 was treated with freshly harvested viable promastigotes from liquid medium as positive Accepted Nov. 2005 control and group 6 was kept as negative control. Leishmanin test was used for estimation of hypersensitivity of skin. Results: Immunization with antigens preparation revealed that, the immunized mice became resistant to infection. Conclusion: Immunization of mice against cutaneous leishmaniasis is possible by using different types of antigens. Key words: Immunisation, cutaneous leishmaniasis, mice.

Published
2006

28. An Experimental Study on the Application of Ultrasonic Technology for Demulsifying Crude Oil and Water Emulsions

Author

Idris M, Dela Rosa N, Abdul Ghani M, Arnel Carvero, Rommel Yrac, and Mahmood Amani

Subjects
Chemistry, business.industry, 020209 energy, Fossil fuel, Mixing (process engineering), 02 engineering and technology, Pulp and paper industry, Glycol dehydration, Basic sediment and water, Diesel fuel, chemistry.chemical_compound, Emulsion, 0202 electrical engineering, electronic engineering, information engineering, Organic chemistry, Petroleum, Gasoline, business
Abstract

An emulsion is the mixture of two immiscible fluids, where one fluid appears as droplets within another. In the oil and gas industry, produced crude oil generally comes with an appreciable amount of water within it in an emulsified form. Before produced crude oil can be prepared for purchase, the water associated with it must be removed. A process known as demulsification is required in order to separate an emulsion into its two phases. In the industry, a number of demulsification techniques are already present; these include thermal, mechanical, chemical, and electrical techniques. Crude oil and gas produced from wells originally come with water, salts, and volatile gases such as oxygen, carbon dioxide, and sometimes hydrogen sulfide, etc. Hence, the petroleum mixture needs to be refined-water, salt, and non-hydrocarbon gases to be separated from the mixture, in order to meet certain oil and gas specifications (which state the maximum concentrations of such contaminants) and make it ready for purchase and transportation. Sonication provides a cheap, simple, and harmless (as it involves mainly the propagation of sound waves) way of separating crude oils from water droplets via demulsification. In addition, if needed, it can be used for emulsification processes as well. Hence, a study of sonification as a way for crude refinement or chemical mixing has important implications for the oil and gas. This investigation proposes the use of ultrasonication as a new and cost-effective technique to aid in the demulsification of crude oil emulsion. The effectiveness of this technique was gauged through its comparison to the already present methods in the industry. Based on the investigation it was found that centrifuge served as the best demulsification method for it reduced the turbidity by 86%. In addition, the reduced turbidity achieved with proposed ultrasonication method ranges from 20%-60%.

Published
2017
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30. Effects of different metabolic states and surgical models on glucose metabolism and secretion of ileal L‐cell peptides: results from the HIPER‐1 study.

Author

Cagiltay, E., Celik, A., Dixon, J. B., Pouwels, S., Santoro, S., Gupta, A., Ugale, S., and Abdul‐Ghani, M.

Subjects
HYPERGLYCEMIA prevention, ILEUM surgery, TYPE 2 diabetes diagnosis, BARIATRIC surgery, BLOOD sugar, CLINICAL trials, CONFERENCES & conventions, GASTRECTOMY, GLUCOSE tolerance tests, INGESTION, INSULIN resistance, ISLANDS of Langerhans, LEANNESS, POSTOPERATIVE period, GLUCAGON-like peptide 1, GUT microbiome, GASTRIC bypass
Abstract

Aim: To compare the impact of four surgical procedures (mini‐gastric bypass, sleeve gastrectomy, ileal transposition and transit bipartition) vs medical management on gut peptide secretion, β‐cell function and resolution of hyperglycaemia in people with type 2 diabetes. Research design and methods: A mixed‐meal tolerance test was administered 6–24 months after each surgical procedure (mini‐gastric bypass, sleeve gastrectomy, ileal transposition and transit bipartition; n=30 in each group) and the results were compared with those obtained in matched lean (n=30) and obese (n=30) people with type 2 diabetes undergoing medical management. Results: Participants in the mini‐gastric bypass and ileal transposition groups had a greater increase in plasma glucose concentration after the mixed‐meal tolerance test than those in the sleeve gastrectomy and transit bipartition groups. Participants in the mini‐gastric bypass group exhibited the greatest increase in the incremental area under the curve of plasma glucose concentration above baseline (P<0.0001). Insulin sensitivity was similar across surgical groups, and statistically greater in participants in the surgical groups than in obese participants in the non‐surgical group (P<0.0001). β‐cell responsiveness to glucose was greater in participants in the sleeve gastrectomy and transit bipartition groups than in the mini‐gastric bypass and ileal transposition groups (P<0.001) despite a smaller incremental increase above baseline in the area under the plasma glucagon‐like peptide‐1 concentration curve relative to ileal transposition. Postoperative β‐cell function was the strongest predictor of hyperglycaemia resolution. Conclusions: The present study showed that the level of β‐cell function after bariatric surgery is the strongest predictor of hyperglycaemia resolution. The study also demonstrates a disconnect between postprandial GLP‐1 levels and β‐cell function among the studied surgical procedures. What's new?: The effects of four different surgical procedures (one‐anastomosis mini‐gastric bypass, sleeve gastrectomy, ileal transposition and transit bipartition])were compared with those of medical management on gut peptide secretion, β‐cell function and resolution of hyperglycaemia in participants with type 2 diabetes mellitus.The level of β‐cell function after bariatric surgery was the strongest predictor of hyperglycaemia resolution.There is a disconnect between postprandial glucagon‐like peptide‐1 levels and β‐cell function between the studied surgical procedures. [ABSTRACT FROM AUTHOR]

Published
2020
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31. Bilateral ear swelling and cough

Author

Mroue, Kamel H., Arayssi, Thurayya K., and Kibbi, Abdul-Ghani M.

Subjects
Shortness of breath -- Research, Physicians -- Practice, Connective tissue diseases -- Risk factors, Connective tissue diseases -- Research, Health
Abstract

Relapsing polychondritis is a rare and possibly fatal disease that causes chronic inflammation and destroys cartilaginous forms in the body. Physicians should watch out for chronic ear or nose inflammation accompanied with unexplained dyspnea, cough or hoarseness.

Published
2004

32. Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart

Author

Abdul-Ghani, M. (Mohammad), Suen, C. (Colin), Jiang, B. (Baohua), Deng, Y. (Yupu), Weldrick, J.J. (Jonathan J.), Putinski, C. (Charis), Brunette, S. (Steve), Fernando, P. (Pasan), Lee, T.T. (Tom T), Flynn, P. (Peter), Leenen, F.H.H. (Frans H.H.), Burgon, P.G. (Patrick G.), Stewart, D.J. (Duncan J.), Megeney, L.A. (Lynn A.), Abdul-Ghani, M. (Mohammad), Suen, C. (Colin), Jiang, B. (Baohua), Deng, Y. (Yupu), Weldrick, J.J. (Jonathan J.), Putinski, C. (Charis), Brunette, S. (Steve), Fernando, P. (Pasan), Lee, T.T. (Tom T), Flynn, P. (Peter), Leenen, F.H.H. (Frans H.H.), Burgon, P.G. (Patrick G.), Stewart, D.J. (Duncan J.), and Megeney, L.A. (Lynn A.)

Abstract

The post-natal heart adapts to stress and overload through hypertrophic growth, a process that may be pathologic or beneficial (physiologic hypertrophy). Physiologic hypertrophy improves cardiac performance in both healthy and diseased individuals, yet the mechanisms that propagate this favorable adaptation remain poorly defined. We identify the cytokine cardiotrophin 1 (CT1) as a factor capable of recapitulating the key features of physiologic growth of the heart including transient and reversible hypertrophy of the myocardium, and stimulation of cardiomyocyte-derived angiogenic signals leading to increased vasc

Published
2017
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36. Bilateral ear swelling and cough

Author

Thurayya Arayssi, Kamel Mroue, and Abdul-Ghani M. Kibbi

Subjects
Ear swelling, business.industry, Medicine, General Medicine, Anatomy, business
Abstract

DAMIANI JM, 1979, LARYNGOSCOPE, V89, P929; DUNNE JA, 1994, CHEST, V105, P864, DOI 10.1378-chest.105.3.864; ENG J, 1991, ANN THORAC SURG, V51, P686; HEDFORS E, 1982, DERMATOLOGICA, V164, P47; MARTIN J, 1976, ARCH DERMATOL, V112, P1272, DOI 10.1001-archderm.112.9.1272; MCADAM LP, 1976, MEDICINE, V55, P193, DOI 10.1097-00005792-197605000-00001; MICHET CJ, 1986, ANN INTERN MED, V104, P74; MOHSENIFAR Z, 1982, CHEST, V81, P711, DOI 10.1378-chest.81.6.711; ROWELL NR, 1973, BRIT J DERMATOL, V88, P387; Sarodia BD, 1999, CHEST, V116, P1669, DOI 10.1378-chest.116.6.1669; VARRANCO VP, 1976, ARCH DERMATOL, V112, P1286; WEINBERGER A, 1979, ARCH DERMATOL, V115, P980, DOI 10.1001-archderm.115.8.980; Zeuner M, 1997, J RHEUMATOL, V24, P96

Published
2004
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37. Physical activity could reduce violent behavior among undergraduate Sport Science students

Author

Harafsheh, Ibrahim Mohammad, Salameh, Ibrahim Abdul Ghani M., alkhaldi, Hasan, Harafsheh, Ibrahim Mohammad, Salameh, Ibrahim Abdul Ghani M., and alkhaldi, Hasan

Abstract

The purpose of this study was to determine whether Physical activity could reduce violent behavior among undergraduate Sport Science students and may differ according to gender. The sample of study consisted of (80) male and female students of the expected graduating students in the Faculty at a rate of (%80) from the original community. a questionnaire consisted of (10) paragraphs was used. And after doing the suitable statistical treatments it was pin-pointed that practicing the sport activities has a big role in belittling the level of violence and at a very big degree amongst students of the Faculty of Physical Education and Sport Science in theHashemiteUniversity, and there are no differences between males and females. The researchers recommended with the necessity of preparing more studies about the phenomenon of violence for the different age stages.

Published
2015

38. LITHOLOGICAL VARIATIONS IN BLACK SHALES AND MUDSTONE FORMATIONS OF CENTRAL SARAWAK, MALAYSIA.

Author

Ibrahim, Walaa Elnasir, Rafek, Abdul Ghani M. D., and Salim, Ahmed Mohamed Ahmed

Subjects
*PETROLOGY, *SHALE
Abstract

This paper examines the Cretaceous - Upper Pliocene shale and mudstone outcrops in Central Sarawak. Related geological studies focused basically on sandstone and coals of Sarawak Basin, with no comprehensive outcrop study on lithological variations in the black shales and mudstone formations. Detailed lithological variations of these formations will allow us discretize potential shale gas intervals. Therefore, the aim of this study is to investigate the field geological characteristics of the Black shales and mudstone formations of Central Sarawak by using outcrop description, sedimentary log analysis, spectral gamma ray (SGR) data and geochemical characteristics (TOC %) of the selected mudstones and black shales. The study covers Nyalau, Tatau, Begrih, Liang and Belaga formations. Representative samples of the formations were subjected to detailed description in terms of lithology, structures and stratigraphy. Features such as laminations, sandstone intercalations, coal lenses, iron nodules, phyllite inclusions and fault structures were identified in the black shale and mudstone. The lowest U (ppm) was recorded for Belaga Formation, which can be attributed to the low grade metamorphism of the Formation, whereas the higher U (ppm) in Tatau and other formations is possibly due to their relatively higher clay content. The TOC values for all formations varied from 0.8% to 3.17%, suggesting they have fair to good hydrocarbon generative potential. [ABSTRACT FROM AUTHOR]

Published
2018

41. Exhaled breath condensate pH and hydrogen peroxide as non-invasive markers for asthma

Author

Amina H, Al-Obaidy and Abdul-Ghani M, Al-Samarai

Subjects
Adult, Adolescent, Hydrogen Peroxide, Hydrogen-Ion Concentration, Middle Aged, Severity of Illness Index, Asthma, Breath Tests, Predictive Value of Tests, Case-Control Studies, Forced Expiratory Volume, Humans, Colorimetry, Biomarkers
Abstract

To estimate the predictive value of exhaled breath condensate (EBC) hydrogen peroxide (H2O2) concentration and pH as non-invasive markers in asthma.Fifty patients with unstable, steroid naive atopic asthma were included in the study, 25 with intermittent asthma and 25 with persistent asthma. Asthma diagnosis was according to the National Heart Lung and Blood Institute guidelines for the diagnosis and management of asthma. Forced expiratory volume in one second (FEV1) was measured by computerized spirometry. The EBC H2O2 assay was carried out using the colorimetric assay. The study was conducted from January to December 2005 in the Asthma and Allergy Center, Tikrit, Iraq.The EBC H2O2 concentration was higher in the asthmatic group (0.91 micromol) as compared with the control (0.23 micromol). There was an inverse correlation between EBC H2O2 concentration and FEV1 predicted percent for asthmatic patients. The mean EBC pH was lower in the asthmatic than the control group. There was a positive correlation between EBC pH and FEV1 predicted percent for asthmatic patients. There was an inverse correlation between EBC H2O2 concentration and pH for all asthmatic patients, intermittent, and persistent asthmatic groups.Exhaled breath condensate hydrogen peroxide concentration and pH was a good non-invasive marker for asthma, whether it was with a persistent or intermittent course.

Published
2007

42. Bilateral ear swelling and cough. Relapsing polychondritis

Author

Kamel H, Mroue, Thurayya K, Arayssi, and Abdul-Ghani M, Kibbi

Subjects
Adult, Male, Folic Acid, Methotrexate, Cough, Antirheumatic Agents, Anti-Inflammatory Agents, Hematinics, Humans, Prednisone, Polychondritis, Relapsing, Otitis Externa
Published
2004

45. Virtual Werribee : a planning support tool

Author

Chan, F., Marinova, D., Anderssen, R. S., Abdul Ghani, M. Z., Datta, S., Beynon, D., Chan, F., Marinova, D., Anderssen, R. S., Abdul Ghani, M. Z., Datta, S., and Beynon, D.

Abstract

Virtual Werribee is collaborative research in applying 3-D modelling and visualisation as a planning support tool in comparison to 2-D plans and drawings. It was a joint initiative involving Deakin University and the Wyndham City Council to demonstrate the use of 3-D visualisation for planning process in the actual context of a planning authority in Australia. The objective of this project was to assist the council in preparing for the revised Local Structure Plan. By reconstructing the council’s data into easily understood information, 3-D model and visualisation served as a verification and discussion tool for decision making. The integration of wider site context also provided a better understanding of the surrounding development areas. This could equip other stakeholders as well as the community to participate in council’s planning agenda activities, such as increasing the urban density and building heights limit. Virtual Werribee included the development planning agenda, categorised as new, re-development and hypothetical. The modelling process progressed with sufficient data from the council. Some changes to the initial plan were made, including the use of CAD modelling software instead of GIS software, and production of a block model with selected detail buildings, instead of a full draped 3-D model. The council decided that the block model would be sufficient for their planning purposes. This was determined while taking into consideration the available facilities at the council. The potentials of the model as a planning tool were demonstrated in this paper, and further compared to the council’s existing materials prepared by the project developers. The advantages of the 3-D interactive model and visualisation over the conventional materials have provided the council officer with a tool for better empowerment in the planning process. This was also evident in the increasing engagement level between the officer and the mo

Published
2011

46. Virtual Werribee: A planning support tool

Author

Felix Chan, Dora Marinova, RS Anderssen, Abdul Ghani, M., Datta, Sambit, Beynon, D., Felix Chan, Dora Marinova, RS Anderssen, Abdul Ghani, M., Datta, Sambit, and Beynon, D.

Abstract

Virtual Werribee is collaborative research in applying 3-D modelling and visualisation as a planning support tool in comparison to 2-D plans and drawings. It was a joint initiative involving Deakin University and Wyndham City Council to demonstrate the use of 3-D visualisation for planning process in the actual context of a planning authority in Australia. The objective of this project was to assist the council in preparing for the revised Local Structure Plan. By reconstructing the council's data into easily understood information, 3-D model and visualisation served as a verification and discussion tool for decision making. The integration of wider site context also provided a better understanding of the surrounding development areas. This could equip other stakeholders as well as the community to participate in council's planning agenda activities, such as increasing the urban density and building heights limit. Virtual Werribee included the development planning agenda, categorised as new, re-development and hypothetical. The modelling process progressed with sufficient date from the council. Some changes to the initial plan were made, including the use of CAD modelling software instead of GIS software, and production of a block model with selected detail buildings, instead of a full draped 3-D model. The council decided that the block model would be sufficient for their planning purposes. This was determined while taking into consideration the available facilities at the council.The potentials of the model as a planned tool were demonstrated in this paper, and further compared to the council's existing materials prepared by the project developers. The advantages of the 3-D interactive model and visualisation over the conventional materials have provided the council officer with a tool for better empowerment in the planning process. This was also evident in the increasing engagement level between the officer and the model as the process developed. As a result of t

Published
2011

47. VIRTUAL MELAWATI: Interactive 3D GIS Visualization as Decision Support Tool for Planning Development Process

Author

Prof.dr.H.J.P. Timmermans, Prof.dr.ir.B.de.Vries, Abdul Ghani, M., Datta, Sambit, Prof.dr.H.J.P. Timmermans, Prof.dr.ir.B.de.Vries, Abdul Ghani, M., and Datta, Sambit

Abstract

Virtual Melawati is an environment for developing expertise in the application of 3D interactive visualization and GIS (Geographic Information System) to address problems of the built environment and to test the model as a decision support tool in the context of the local planning authorities in Malaysia. The visual approach enables the integration of highly complex spatial GIS information such as the evolution and transformation of the urban precinct as well as the impact of planned developments into the decision making process. The study will examine the techniques of data acquisition, data reconstruction from physical to digital, urban analysis and visualization in constructing an interactive 3D GIS model to support and assist the decision making process in urban design and planning. The outcomes of the study will deliver an experimental test bed for improving decision making processes in urban planning and design utilizing 3D modeling and GIS. The project will accelerate the uptake of digital and multimedia methods in local government, facilitate current planning and consultation processes between councils and stakeholders and improve the dissemination and management of spatial information about urban environments.

Published
2010

48. Virtual ampang Jaya

Author

Ning Gu, Leman FigenGul, Michael Ostwald, Anthony Williams, Abdul Ghani, M., Datta, Sambit, Ning Gu, Leman FigenGul, Michael Ostwald, Anthony Williams, Abdul Ghani, M., and Datta, Sambit

Abstract

Virtual Ampang Jaya is an interactive visualization environment for modeling urban growth and spatio-temporal transformation to expose and evaluate the different layers of Ampang Jaya, consisting of social, economic, built and natural environments. The research will investigate the techniques of data acquisition, data reconstruction from physical to digital, urban analysis and visualization in constructing a digital model which may include low geometric content such as 2D digital maps and digital orthographics to high geometric content such as full volumetric parametric modeling. The process will integrate the state of the art GIS system to explore GIS powerful analytical and querying capabilities with interactive visualization environment as well as test the model as a predictive tool. The model will set as an experimental test pad in providing a new platform to support decision making about the spatial growth of Ampang Jaya by the various stakeholders in the planning processes. Such an environment will improve the subsequent digital models and research in the area of urban design and planning where visual communication is central.

Published
2009

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