Search

Your search keyword '"Abreu, Pedro F."' showing total 11 results
Start Over Author "Abreu, Pedro F."
11 results on '"Abreu, Pedro F."'

3. The Multi-center Evaluation of the Accuracy of the Contrast MEdium INduced Pd/Pa RaTiO in Predicting FFR (MEMENTOFFR) Study

Author

Leone, Antonio Maria, Martin Reyes, Roberto, Baptista, Sergio B., Amabile, Nicola, Raposo, Lui, Franco Pelaez, Juan Antonio, Trani, Carlo, Cialdella, Pio, Basile, Eloisa, Zimbardo, Giuseppe, Burzotta, Francesco, Porto, Italo, Aurigemma, Cristina, Rebuzzi, Antonio Giuseppe, Faustino, Mariana, Niccoli, Giampaolo, Abreu, Pedro F., Slama, Michel S., Spagnoli, Vincent, Arrieta, Miren Telleria, Amat Santos, Ignacio J., De La Torre Hernandez, Jose M., Palop, Ramon Lopez, Crea, Filippo, Trani, Carlo (ORCID:0000-0001-9777-013X), Burzotta, Francesco (ORCID:0000-0002-6569-9401), Porto, Italo (ORCID:0000-0002-9854-5046), Rebuzzi, Antonio Giuseppe (ORCID:0000-0002-9873-957X), Niccoli, Giampaolo (ORCID:0000-0002-3187-6262), Crea, Filippo (ORCID:0000-0001-9404-8846), Leone, Antonio Maria, Martin Reyes, Roberto, Baptista, Sergio B., Amabile, Nicola, Raposo, Lui, Franco Pelaez, Juan Antonio, Trani, Carlo, Cialdella, Pio, Basile, Eloisa, Zimbardo, Giuseppe, Burzotta, Francesco, Porto, Italo, Aurigemma, Cristina, Rebuzzi, Antonio Giuseppe, Faustino, Mariana, Niccoli, Giampaolo, Abreu, Pedro F., Slama, Michel S., Spagnoli, Vincent, Arrieta, Miren Telleria, Amat Santos, Ignacio J., De La Torre Hernandez, Jose M., Palop, Ramon Lopez, Crea, Filippo, Trani, Carlo (ORCID:0000-0001-9777-013X), Burzotta, Francesco (ORCID:0000-0002-6569-9401), Porto, Italo (ORCID:0000-0002-9854-5046), Rebuzzi, Antonio Giuseppe (ORCID:0000-0002-9873-957X), Niccoli, Giampaolo (ORCID:0000-0002-3187-6262), and Crea, Filippo (ORCID:0000-0001-9404-8846)

Abstract

Aims: Adenosine administration is needed for the achievement of maximal hyperaemia fractional flow reserve (FFR) assessment. The objective was to test the accuracy of Pd/Pa ratio registered during submaximal hyperaemia induced by non-ionic contrast medium (contrast FFR [cFFR]) in predicting FFR and comparing it to the performance of resting Pd/Pa in a collaborative registry of 926 patients enrolled in 10 hospitals from four European countries (Italy, Spain, France and Portugal). Methods and results: Resting Pd/Pa, cFFR and FFR were measured in 1,026 coronary stenoses functionally evaluated using commercially available pressure wires. cFFR was obtained after intracoronary injection of contrast medium, while FFR was measured after administration of adenosine. Resting Pd/Pa and cFFR were significantly higher than FFR (0.93±0.05 vs. 0.87±0.08 vs. 0.84±0.08, p<0.001). A strong correlation and a close agreement at Bland-Altman analysis between cFFR and FFR were observed (r=0.90, p<0.001 and 95% CI of disagreement: from-0.042 to 0.11). ROC curve analysis showed an excellent accuracy (89%) of the cFFR cut-off of ?0.85 in predicting an FFR value ?0.80 (AUC 0.95 [95% CI: 0.94-0.96]), significantly better than that observed using resting Pd/Pa (AUC: 0.90, 95% CI: 0.88-0.91; p<0.001). A cFFR/ FFR hybrid approach showed a significantly lower number of lesions requiring adenosine than a resting Pd/ Pa/FFR hybrid approach (22% vs. 44%, p<0.0001). Conclusions: cFFR is accurate in predicting the functional significance of coronary stenosis. This could allow limiting the use of adenosine to obtain FFR to a minority of stenoses with considerable savings of time and costs.

Published
2016

4. The Multi-center Evaluation of the Accuracy of the Contrast MEdium INduced Pd/Pa RaTiO in Predicting FFR (MEMENTO-FFR) Study

Author

Leone, Antonio Maria, primary, Martin-Reyes, Roberto, additional, Baptista, Sergio B., additional, Amabile, Nicolas, additional, Raposo, Luis, additional, Franco Pelaez, Juan Antonio, additional, Trani, Carlo, additional, Cialdella, Pio, additional, Basile, Eloisa, additional, Zimbardo, Giuseppe, additional, Burzotta, Francesco, additional, Porto, Italo, additional, Aurigemma, Cristina, additional, Rebuzzi, Antonio G., additional, Faustino, Mariana, additional, Niccoli, Giampaolo, additional, Abreu, Pedro F., additional, Slama, Michel S., additional, Spagnoli, Vincent, additional, Telleria Arrieta, Miren, additional, Amat Santos, Ignacio J., additional, de la Torre Hernandez, Jose M., additional, Lopez Palop, Ramon, additional, and Crea, Filippo, additional

Published
2016
Full Text
View/download PDF

7. PCI failure in the Occluded Artery Trial (OAT): Frequency, mechanisms, and outcome

Author

UCL - Cliniques universitaires Saint-Luc, UCL - MD/MINT - Département de médecine interne, Buller, Christopher E., Renkin, Jean, Mancini, John, Dzavik, Vladimir, Pfisterer, Matthias E., Rankin, James M., Carere, Ronald G., Michalis, Lampros K., Forman, Sandra A., Abreu, Pedro F., Lamas, Gervasio A., Hochman, Judith S., 80th Annual Scientific Session of the American-Heart-Association, UCL - Cliniques universitaires Saint-Luc, UCL - MD/MINT - Département de médecine interne, Buller, Christopher E., Renkin, Jean, Mancini, John, Dzavik, Vladimir, Pfisterer, Matthias E., Rankin, James M., Carere, Ronald G., Michalis, Lampros K., Forman, Sandra A., Abreu, Pedro F., Lamas, Gervasio A., Hochman, Judith S., and 80th Annual Scientific Session of the American-Heart-Association

Published
2007

8. Abstract 2986: Did Early Hazard of PCI Offset Late Benefit in the Occluded Artery Trial (OAT)?

Author

Buller, Christopher E, primary, Rankin, James M, additional, Renkin, Jean, additional, Carere, Ronald G, additional, Dzavik, Vladimir, additional, Ruzyllo, Witold, additional, Forman, Sandra A, additional, Buszman, Pawel E, additional, Mancini, G. B. John, additional, Abreu, Pedro F, additional, Lamas, Gervasio A, additional, and Hochman, Judith S, additional

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results