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1. Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-C1-flavin

Author

Ortiz-Maldonado, Mariliz, Aeschliman, Sara M., Ballou, David P., and Massey, Vincent

Subjects
Biochemistry -- Research, Gene mutations -- Physiological aspects, Catalysis -- Physiological aspects, Hydroxylation -- Physiological aspects, Oxygen -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the catalysis of the p-hydroxybenzoate by p-hydroxybenzoate hydroxylase. The results of the oxygen transfer to p-hydroxybenzoate via C4a-hydroperoxide of the flavin are described.

Published
2001

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