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2 results on '"Ali Erhan Ozdemirel"'

1. Usefullnes of atherogenic indices and Ca-LDL level to predict subclinical atherosclerosis in patients with psoriatic arthritis?

Author

Duygu Tecer, Ismihan Sunar, Ali Erhan Ozdemirel, Rabia Tural, Orhan Kucuksahin, Aylin Sepici Dincel, and Sebnem Ataman

Subjects
Atherogenic indexes, Atherosclerosis, Ca-LDL, Carotid intima-media thickness, Psoriatic arthritis, Diseases of the musculoskeletal system, RC925-935, Immunologic diseases. Allergy, RC581-607
Abstract

Abstract Background To investigate the link between carbamylated low-density lipoprotein (ca-LDL), atherogenic index of plasma (AIP), atherogenic coefficient (AC), Castelli’s risk indices I and II (CRI I and II) and subclinic atherosclerosis in psoriatic arthritis (PsA). Methods Thirty-ninepatients and 19 age, sex, body mass index matched healthy controls were included. Insulin resistance (IR) was assessed with homeostasis of model assessment-IR (HOMA-IR). Carotid intima-media thickness (CIMT) was measured at both common carotid arteries and mean CIMT was calculated. Results The mean age was 49.50 ± 11.86 years and 64.1% were females in PsA group. In the PsA group, CIMT and HOMA-IR were significantly higher (p = 0.003, p = 0.043, respectively). AIP, AC, TG/HDL, CRI-1, CRI-2 and ca-LDL levels were similar between groups. In PsA group, CIMT was positively correlated with HOMA-IR, TG/HDL and AIP. Although ca-LDL was positively correlated with serum amyloid A (r = 0.744, p

Published
2019
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2. The evaluation of lung involvement and functional capacities in patients diagnosed with primary Sjogren's syndrome

Author

Derya Yenibertiz, Berna Akinci Ozyurek, Yurdanur Erdogan, Ali Erhan Ozdemirel, and Tugce Sahin Ozdemirel

Subjects
Male, medicine.medical_specialty, High-resolution computed tomography, Disease, law.invention, Pulmonary function testing, law, Internal medicine, medicine, Outpatient clinic, Humans, Respiratory system, Lung, Retrospective Studies, medicine.diagnostic_test, business.industry, General Medicine, respiratory system, Rheumatology, respiratory tract diseases, Peribronchial Thickening, Respiratory Function Tests, Sjogren's Syndrome, Female, medicine.symptom, business, Ground glass, Tomography, X-Ray Computed
Abstract

Introduction: Sjögren syndrome is a chronic, systemic, inflammatory disease characterized with lymphocytic infiltration of the exocrine glands, frequently manifested by dryness in the region affected. Although the most common extraglandular involvement in SS is pulmonary involvement. Early diagnosis and treatment is considered to be important. It was aimed to evaluate the frequency of early lung involvement, high resolution computed tomography (HRCT) findings and data of pulmonary function test (PFT) in SS in this study. Material-Method: Thirty five patients diagnosed with SS and referred by the Department of Rheumatology to determine potential lung involvement to the 8th chest diseases outpatient clinic of our hospital between September 2015 and December 2018 were included in this study. Respiratory signs, demographic features, length of disease and treatment regimens, PFT, data of 6-minute walk test (MWT) and findings of HRCT of the patients were retrospectively obtained from hospital information system and patient files. Results: The mean age of the patients was 54.4 ± 9.2. The majority of the patients were women (94.3%). When the HRCT findings were evaluated, 28 (80%) patients had CT findings, while 7 (20%) patients had no CT findings. The most common HRCT findings found in patients were peribronchial thickening (48.6 %), ground glass appearance (28.6%) and prominence in interstitial scars. Conclusion: We think that the evaluation of HRCT and PFTs in patients diagnosed with SS for assessing early pulmonary involvement will be guiding in terms of follow-up and treatment.

Published
2021

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