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65 results on '"Alkylating Agents analysis"'

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1. Electrochemistry of chemotherapeutic alkylating agents and their interaction with DNA.

2. Novel Pyrene Excimer and Fluorogenic Probe for the Detection of Alkylating Agents.

3. Colorimetric Detection of Carcinogenic Alkylating Fumigants on Nylon-6 Nanofibrous Membrane. Part I: Investigation of 4-( p-Nitrobenzyl)pyridine as a "New" Sensing Agent with Ultrahigh Sensitivity.

4. Direct-acting DNA ethylating agents associated with tobacco use primarily originate from the tobacco itself, not combustion.

5. Determination of 23 perfluorinated alkylated substances in water and suspended particles by ultra-performance liquid chromatography/tandem mass spectrometry.

6. Extraction-spectrophotometric determination of tris(2-chloroethyl)amine using phthaleins.

7. When alcohol is the answer: Trapping, identifying and quantifying simple alkylating species in aqueous environments.

8. Pharmacogenomic study using bio- and nanobioelectrochemistry: Drug-DNA interaction.

9. Concentration Accuracy of Compounded Mitomycin C for Ophthalmic Surgery.

10. New validated LC-MS/MS method for the determination of three alkylated adenines in human urine and its application to the monitoring of alkylating agents in cigarette smoke.

11. Development and validation of a sensitive GC-MS method for the determination of alkylating agent, 4-chloro-1-butanol, in active pharmaceutical ingredients.

12. Assay at low ppm level of dimethyl sulfate in starting materials for API synthesis using derivatization in ionic liquid media and LC-MS.

13. Determination of polar alkylating agents.

14. Matrix deactivation: A general approach to improve stability of unstable and reactive pharmaceutical genotoxic impurities for trace analysis.

15. Alkylation of sperm DNA is associated with male factor infertility and a reduction in the proportion of oocytes fertilised during assisted reproduction.

16. The Viracept-EMS case: impact and outlook.

17. Ethyl methanesulfonate toxicity in Viracept--a comprehensive human risk assessment based on threshold data for genotoxicity.

18. Reichardt's dye and its reactions with the alkylating agents 4-chloro-1-butanol, ethyl methanesulfonate, 1-bromobutane and Fast Red B - a potentially useful reagent for the detection of genotoxic impurities in pharmaceuticals.

19. Control and analysis of alkyl and benzyl halides and other related reactive organohalides as potential genotoxic impurities in active pharmaceutical ingredients (APIs).

20. A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry.

21. Near infrared spectroscopy and process analytical technology to master the process of busulfan paediatric capsules in a university hospital.

22. [Simultaneous determination of 7-methylguanosine and mitomycin C by capillary electrophoresis with amperometric detection].

23. Mono- and diiodocyclophosphamide as possible internal standards for cyclophosphamide quantification: characterization by ion trap multi-stage mass spectrometry and effects of iodine-chlorine substitution on the fragmentation pattern.

24. Alkylation power of free Immobiline chemicals towards proteins in isoelectric focusing and two-dimensional maps, as explored by matrix assisted laser desorption/ionization-time of flight-mass spectrometry.

25. Determination of N,N-dimethylaminoethyl chloride and the dimethylaziridinium ion at sub-ppm levels in diltiazem hydrochloride by LC-MS with electrospray ionisation.

26. An HPLC assay utilizing solid-phase extraction for CI-1010, an alkylating radiosensitizer, in rat plasma.

27. Gas chromatographic/mass spectrometric analysis of methyl methanesulphonate and ethyl methanesulphonate in the bismesylate salt of DPI 201-106, a positive inotropic agent for the treatment of heart failure.

28. Tobacco smoke-associated N7-alkylguanine in DNA of larynx tissue and leucocytes.

29. N-alkylvaline levels in globin as a new type of biomarker in risk assessment of alkylating agents.

30. [Synthesis of oligodeoxyribothymidylate derivatives containing alkylating groups and residues of biotin, for directed modification of chromatin].

31. The prospects of the development of the method for monitoring of occupational exposure to some alkylating agents.

32. Trapping and measurement of short-lived alkylating agents in a recirculating flow system.

33. [Determination of alkylation of bacterial DNA as a rapid test for toxicological evaluation of alkylating xenobiotic agents].

34. Activity of cyclophosphamide and 1-methylnitrosourea on Ehrlich carcinoma transplanted in different sites. Correlation between drug level and tumor inhibition.

36. Estimation of exposure to alkylating carcinogens by the GC-MS determination of adducts to hemoglobin and nucleic acid bases in urine.

37. Identification of guanine-adducts of carcinogens by their fluorescence.

38. Alkylating activity in food products--especially sauerkraut and sour fermented dairy products--after incubation with nitrite under quasi-gastric conditions.

40. Quantitative determination of carcinogens and mutagens as alkylating agents following chemical activation.

41. Analysis of atomospheric carcinogens and their cofactors.

42. Derivatization of carboxylic acids by reaction with 4'-bromophenacyl trifluoromethanesulfonate prior to determination by high-performance liquid chromatography.

43. [EPR study of the denitrosation of alkylnitrosoureas in vivo].

44. Protein-carcinogen adducts in human dosimetry.

45. Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3'-terminus and their interaction with DNA within mammalian cells.

46. [Quantitative determination of alkylating cytostatics on TLC plate with 4-pyridinecarboxaldehyde-2-benzothiazolylhydrazone].

47. [Iodochlorometric determination of dopan, thiophosphamide, thiodipin and imiphos].

48. In-vitro assays to detect alkylating and mutagenic activities of dietary components nitrosated in situ.

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