30 results on '"Alonso De Diego, Sergio A."'
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2. Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR2Negative Allosteric Modulators with In VivoActivity in a Rodent’s Model of Cognition
3. Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads
4. Correction to Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate
5. Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate
6. Preliminary investigation of 6,7-dihydropyrazolo[1,5-a]pyrazin-4-one derivatives as a novel series of mGlu5 receptor positive allosteric modulators with efficacy in preclinical models of schizophrenia
7. Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
8. 1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu2/3Receptors
9. Preliminary investigation of 6,7-dihydropyrazolo[1,5- a ]pyrazin-4-one derivatives as a novel series of mGlu 5 receptor positive allosteric modulators with efficacy in preclinical models of schizophrenia
10. 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads
11. Miméticos de GPE y cPG: ¿una nueva familia de agentes neuroprotectores?
12. 1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu2/3 Receptors.
13. Studies on structure-activity relationships of the neuroprotective tripeptide H-Gly-Pro-Glu-OH (GPE)
14. Identification of a Novel Orally Bioavailable Phosphodiesterase 10A (PDE10A) Inhibitor with Efficacy in Animal Models of Schizophrenia.
15. New Gly-Pro-Glu (GPE) analogues: Expedite solid-phase synthesis and biological activity
16. The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity
17. Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE): synthesis and structure–activity relationships
18. Imidazo[1,2-a]pyridines: Orally Active Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor
19. Preparation of amides mediated by isopropylmagnesium chloride under continuous flow conditions
20. The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity
21. New Gly-Pro-Glu (GPE) analogues: Expedite solid-phase synthesis and biological activity
22. Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE): synthesis and structure–activity relationships
23. Efficient Synthesis of Enantiomerically Pure ?-Alkyl Cyclopropanecarbonitrile Derivatives from Pyrazolines.
24. Efficient Synthesis of Enantiomerically Pure α-Alkyl Cyclopropanecarbonitrile Derivatives from Pyrazolines†
25. ChemInform Abstract: (Z)‐3‐p‐Tolylsulfinylacrylonitriles as Chiral Dipolarophiles: Reactions with Diazoalkanes.
26. (Z)-3-p-Tolylsulfinylacrylonitriles as Chiral Dipolarophiles: Reactions with Diazoalkanes
27. Identification of a NovelOrally Bioavailable Phosphodiesterase 10A (PDE10A) Inhibitor withEfficacy in Animal Models of Schizophrenia.
28. Efficient Synthesis of Enantiomerically Pure α-Alkyl Cyclopropanecarbonitrile Derivatives from Pyrazolines.
29. Discovery of 6,7-Dihydropyrazolo[1,5- a ]pyrazin-4(5 H )-one Derivatives as mGluR 2 Negative Allosteric Modulators with In Vivo Activity in a Rodent's Model of Cognition.
30. Efficient synthesis of enantiomerically pure alpha-alkyl cyclopropanecarbonitrile derivatives from pyrazolines.
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