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31 results on '"Anita, Yulia"'

3. Integrated Life Cycle Assessment and Techno-economic Analysis for Ionic Liquids-based Biomass Delignification Process

Author

Putra Agusta Samodra and Anita Yulia

Subjects
Environmental sciences, GE1-350
Abstract

Ionic liquids (ILs) are a sort of green solvent that possess considerable promise for many industrial applications, such as the delignification of biomass. This study conducted an integrated life cycle assessment (LCA) and techno-economic analysis (TEA) of the utilization of 1 g of ILs for the ionosolv delignification process. [bmim][Cl] was selected as a case study. By using the CML 2001 environmental impact analysis method, 1 g of 1-butyl-3-methylimidazolium chloride [bmim][Cl] utilization for the ionosolv delignification process emitted 3.67 g CO2 eq of GWP100, 0.013 g SO2 eq of acidification potential, 0.015 g PO43- eq of eutrophication potential, and 32.417 g 1,4-DCB eq of HTP 20a.

Published
2024
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7. Does Happiness Depend On Socioeconomic Conditions? Knowledge Gained From Indonesia

Author

Syaiful Anwar, Anita Yulia Sari, Nasri Bachtiar, and Rahmi Fahmy

Abstract

The objective of this study is to identify and examine the socioeconomic variables that affect happiness in Indonesia. Secondary data from the Indonesia Family Life Survey (IFLS) batch 5 survey, which included 16,698 respondents, was the source of the information used in this study. The probit model is used in the data analysis technique using a multilevel category as the dependent variable. According to the study's findings, age, gender, social capital, including religious observance and a sense of security, variable consumer spending, and willingness to help variables have no bearing on the likelihood of happiness in Indonesia. Neither do income level, health, education, or age. Income, education, health, and social capital levels

Published
2022

10. Synthesis of licarin A from isoeugenol catalyzed by Brassica juncea peroxidase and its cytotoxicity on MCF-7 cell line.

Author

Anita, Yulia, Sundowo, Andini, Hanafi, Muhammad, Lotulung, Puspa Dewi N., and Istyastono, Enade Perdana

Subjects
*BRASSICA juncea, *ESTROGEN receptors, *CELL lines, *NUCLEAR magnetic resonance, *PEROXIDASE, *MASS spectrometers
Abstract

By employing crude peroxidases extracted from sawi hijau (Brassica juncea) as biocatalyst, licarin A was synthesized from isoeugenol. The structure was elucidated and confirmed by mass spectrometer (MS) and nuclear magnetic resonance (NMR) analysis. This compound displayed moderate cytotoxicity effect on MCF-7 breast cancer cell with IC50 = 59.95±1.87 µg/mL, compared to doxorubicin with IC50 value of 0.88±0.34 µg/mL as the positive control. These results are indirectly in line with our previously published in silico tests which indicated that licarin A was not a potent ligand for estrogen receptor alpha (ERα), but either a non-ligand or a moderate ligand for ERα. [ABSTRACT FROM AUTHOR]

Published
2022
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11. Partial purification of peroxidase from kailan (Brassica oleraceae var Alboglabra) by micro- and ultrafiltration membrane.

Author

Melanie, Hakiki, Anita, Yulia, Aspiyanto, Susilowati, Agustine, Maryati, Yati, Mulyani, Hani, and Budiari, Setyani

Subjects
*ULTRAFILTRATION, *BRASSICA, *INORGANIC compounds, *SEPARATION (Technology), *PEROXIDASE, *APPROPRIATE technology, *ORGANIC compounds
Abstract

Peroxidase enzymes are a group of oxidoreductase enzymes that catalyse the reduction of peroxides such as hydrogen and oxidise organic and inorganic compounds. Membrane processing is a promising alternative technology for the separation and purification of enzymes. This study partially purified peroxidase from Kailan (Brassica oleraceae var Alboglabra) by micro-and ultrafiltration membrane technology. The effects of physicochemical conditions (pH and temperature) on peroxidase were examined, and the purity and enzyme activity of resulted peroxidase was also determined. The crude peroxidase enzyme isolated from Kailan was passed through a microfiltration membrane (0.15 µm) with pressure 40 psia, rotation speed 400 rpm, and a flow rate of 30 mL/min, followed by an ultrafiltration module with the pressure of 40 psia and rotation speed 200, 300 and 400 rpm at room temperature. The optimum pH and temperature of peroxidase were pH 6.0 and 27 °C, respectively, as determined with guaiacol as the substrate. The purification of peroxidase by micro-and ultrafiltration process at optimum conditions resulted in specific activity of 392.16 and 749.91 U/mg with a purity level of 5.20 and 9.95 fold than crude enzyme activity. Thus, the membrane technology has a potential purification method for peroxidase production. [ABSTRACT FROM AUTHOR]

Published
2022
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12. DOES HAPPINESS DEPEND ON SOCIOECONOMIC CONDITIONS? KNOWLEDGE GAINED FROM INDONESIA.

Author

Anwar, Syaiful, Sari, Anita Yulia, Bachtiar, Nasri, and Fahmy, Rahmi

Subjects
*HAPPINESS, *CONSUMPTION (Economics), *FAMILIES, *RITES & ceremonies, *SECONDARY analysis, *DEPENDENT variables, *SOCIAL capital
Abstract

The objective of this study is to identify and examine the socioeconomic variables that affect happiness in Indonesia. Secondary data from the Indonesia Family Life Survey (IFLS) batch 5 survey, which included 16,698 respondents, was the source of the information used in this study. The probit model is used in the data analysis technique using a multilevel category as the dependent variable. According to the study's findings, age, gender, social capital, including religious observance and a sense of security, variable consumer spending, and willingness to help variables have no bearing on the likelihood of happiness in Indonesia. Neither do income level, health, education, or age. Income, education, health, and social capital levels [ABSTRACT FROM AUTHOR]

Published
2023

13. Synthesis of gem‐difluoroalkenes via photoredox‐catalyzed defluoroaryloxymethylation of α‐trifluoromethyl alkenes.

Author

Atriardi, Shafrizal Rasyid, Kim, Jae‐Young, Anita, Yulia, and Woo, Sang Kook

Subjects
ALKENES, FUNCTIONAL groups
Abstract

Herein, we present a novel method for the synthesis of gem‐difluoroalkenes via visible‐light photoredox‐catalyzed defluoroaryloxymethylation of α‐trifluoromethyl alkenes using α‐silyl ethers as aryloxymethyl radical precursors. This reaction shows good functional group tolerance and provides the desired products in good to excellent yields. Based on mechanistic studies, we propose a reaction mechanism involving single‐electron oxidation of an α‐silyl ether to generate an α‐aryloxymethyl radical. [ABSTRACT FROM AUTHOR]

Published
2023
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15. Synthesis of gem‐difluoroalkenesvia photoredox‐catalyzeddefluoroaryloxymethylation of α‐trifluoromethylalkenes

Author

Atriardi, Shafrizal Rasyid, Kim, Jae‐Young, Anita, Yulia, and Woo, Sang Kook

Abstract

Herein, we present a novel method for the synthesis of gem‐difluoroalkenes via visible‐light photoredox‐catalyzed defluoroaryloxymethylation of α‐trifluoromethyl alkenes using α‐silyl ethers as aryloxymethyl radical precursors. This reaction shows good functional group tolerance and provides the desired products in good to excellent yields. Based on mechanistic studies, we propose a reaction mechanism involving single‐electron oxidation of an α‐silyl ether to generate an α‐aryloxymethyl radical. A gem‐difluoroalkenes are privileged structural motifs because their geometric and electronic properties are similar to those of aldehydes, ketones, and esters. A novel method for the synthesis of gem‐difluoroalkenes via visible‐light photoredox‐catalyzed defluoroaryloxymethylation of α‐trifluoromethyl alkenes using α‐silyl ethers as aryloxymethyl radical precursors was developed.

Published
2023
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18. Pengaruh Nafas Dalam dan Posisi Terhadap Saturasi Oksigen dan Frekuensi Nafas Pada Pasien Asma

Author

Dahrizal Dahrizal, Widia Lestari, and Anita Yulia

Subjects
Deep breath, Respiratory rate, business.industry, Diaphragmatic breathing exercises, Anesthesia, Mann–Whitney U test, Breathing, Medicine, Diaphragmatic breathing, business, medicine.disease, Lung function, Asthma
Abstract

Asthma is a disorder of chronic inflammation of the airways which causes shortness of breath so that in clinical conditions there will be a decrease in oxygen saturation. One intervention that can be done in asthma patients to maximize pulmonary ventilation is diaphragmatic breathing exercises. This study aimed to determine the effect of deep breath and position on the oxygen saturation (SpO2) and respiratory rate (RR)in asthma patients. This study used a quasi-experimental design with pretest-posttest with control group. In this study the sample was taken using consequtives sampling with 15 people in one group and the entire study sample was 30 people. Measuring the SpO2 value of patients using Oxymetri and the frequency of breathing using a stopwatch for one minute. Intervention of deep breathing techniques and positioning and after observation for 30 minutes. The analysis used the Mann Whitney test. The results of the study showed the influence of deep breathing intervention and position on the SpO2 value of asthma patients (P Value = 0.001) and there was influence of deep breathing intervention and position on the RR value of asthma patients (P Value = 0.001). Asthma can be realized by proper management of asthma. Appropriate management includes making lung function close to normal, preventing recurrence of the disease to prevent death.

Published
2019

24. Faktor-faktor yang Berhubungan dengan Daya Terima Makanan Lunak Pasien Rawat Inap Penyakit Dalam RSUD Pasaman Barat Kabupaten Pasaman Barat Tahun 2016

Author

Anita, Yulia Anwar

Subjects
RA0421 Public health. Hygiene. Preventive Medicine
Abstract

Tujuan Penelitian Daya terima makanan lunak dipengaruhi oleh berbagai faktor yaitu faktor internal dan eksternal. Penelitian ini bertujuan untuk mengetahui faktor-faktor (penampilan makanan, rasa makanan, menu makanan, penyajian makanan, pelayanan penyaji makanan) yang berhubungan dengan daya terima makanan lunak di ruang rawat inap penyakit dalam RSUD Pasaman Barat Tahun 2016. Metode Penelitian ini menggunakan desain cross sectional study dengan sampel 92 orang. Teknik pengambilan sampel dengan menggunakan purposive sampling. Penelitian dilakukan pada pasien berumur 18-60 tahun di ruang rawat inap penyakit dalam RSUD Pasaman Barat yang mendapat makanan lunak pada bulan Maret 2016. Data diolah dan dianalisis dengan uji Chi Square dengan tingkat kepercayaan 95%. Hasil Hasil penelitian 55,4% responden daya terima kurang, 62,0% responden menilai penampilan makanan kurang, 51,1% responden menilai rasa makanan kurang, 52,2% responden menilai menu makanan kurang, 23,9% responden menilai penyajian makanan kurang, 18,5% responden menilai pelayanan penyaji makanan kurang. Hasil uji statistik terdapat hubungan antara variabel penampilan (p value = 0,001 ), rasa (p value = 0,022 ), menu (p value = 0,004), penyajian makanan (p value = 0,009) dengan daya terima makanan dan tidak terdapat hubungan antara variabel pelayanan penyaji (p value = 0,561) dengan daya terima makanan. Kesimpulan Ada hubungan antara penampilan, rasa, menu dan penyajian makanan dengan daya terima makanan lunak, sedangkan tidak terdapat hubungan yang bermakna antara pelayanan penyaji dengan daya terima makanan. Kepada petugas instalasi gizi agar memperbaiki dan mengevaluasimakanan lunak yang diberikan baik dari segi penampilan, rasa, menu dan penyajian makanan untuk meningkatkan daya terima pasien terhadap makanan lunak. Daftar Pustaka : 44 (1981-2015) Kata Kunci : Daya Terima, Makanan Lunak

Published
2016

26. Bioactivities Examination of Cinchona Leaves Ethanol Extracts.

Author

Artanti, Nina, Udin, Linar Z., Hanafi, M., Jamilah, Kurniasih, Ida Rahmi, Primahana, Gian, Anita, Yulia, Sundowo, Andini, and Kandace, Yoice Sri

Subjects
CINCHONA, ETHANOL, PLANT extracts, ALPHA-glucosidases, DIABETES prevention, ANTIOXIDANTS, CYTOTOXINS
Abstract

Cinchona species especially the barks are commonly known for commercial production of quinine as antimalarial. Although it is also reported for treatment of depurative, whooping cough, influenza and dysentery. In this paper we reported in vitro examination of other bioactivities (antidiabetes, antioxidant and in vitro cytotoxicity) of 70% ethanol extract of Cinchona ledgeriana and C. succirubra leaves as well as qunine, quinidine, and cinchonine the major alkaloids found in Cinchona species. Antidiabetes was conducted using α-glucosidase inhibitory activity assay. Antioxidant was conducted using DPPH free radical scavenging activity assay. In vitro cytotoxic activity was concucted by microscopic observation on growth of breast cancer cell line MCF-7. The results showed that at concentration of 100 μg/ml, C. ledgeriana leaves ethanol extracts showed the best activity as antidiabetes (98% inhibitory of α-glucosidase activity) and antioxidant (92% DPPH free radical scavenging activity), whereas at the same concentration C. succirubra, quinine, quinidine and cinchonine showed very low activities of antidiabetes and antioxidant. Microscopic observation of in vitro cytotoxicity showed that C. ledgeriana also has excellent cytotoxicity to breast cancer cell line MCF-7 which better than quinine, quinidine and cinchonine, whereas C. succirubra showed low cytotoxicity. These results suggest that cinchona species have many potential as the source of drugs discovery and development other than just for malaria treatment. Therefore it is important to conduct further studies and to maintain the available Cinchona plantation in Indonesia. [ABSTRACT FROM AUTHOR]

Published
2017
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31. Structure-based design of eugenol analogs as potential estrogen receptor antagonists.

Author

Anita Y, Radifar M, Kardono LB, Hanafi M, and Istyastono EP

Abstract

Eugenol is an essential oil mainly found in the buds and leaves of clove (Syzygium aromaticum (L.) Merrill and Perry), which has been reported to have activity on inhibition of cell proliferation and apoptosis induction in human MCF-7 breast cancer cells. This biological activity is correlated to its activity as an estrogen receptor antagonist. In this article, we present the construction and validation of structure-based virtual screening (SBVS) protocols to identify the potent estrogen receptor α (ER) antagonists. The selected protocol, which gave acceptable enrichment factors as a virtual screening protocol, subsequently used to virtually screen eugenol, its analogs and their dimers. Based on the virtual screening results, dimer eugenol of 4-[4-hydroxy-3-(prop-2-en-1- yl)phenyl]-2-(prop-2-en-1-yl)phenol is recommended to be developed further in order to discover novel and potent ER antagonists.

Published
2012
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