1. Simultaneous feeding of calcium butyrate and tannin extract decreased the incidence of diarrhea and proinflammatory markers in weaned piglets
- Author
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Camila Demarco Maito, Antonio Diego Brandão Melo, Angela Cristina da Fonseca de Oliveira, Jansller Luiz Genova, Jair Rodini Engracia Filho, Renata Ernlund Freitas de Macedo, Kelly Mazutti Monteiro, Saulo Henrique Weber, Astrid Koppenol, and Leandro Batista Costa
- Subjects
antimicrobial ,immune-expression ,intestinal histology ,organic acid ,phytogenic ,weaning piglets ,Zoology ,QL1-991 - Abstract
Objective This study was conducted to investigate the effect of associating calcium butyrate with tannin extract, compared to an antimicrobial on the growth performance, incidence of diarrhea, intestinal histology, immune-expression of cyclooxygenase-2 (COX-2) and tumor necrosis factor α (TNF-α) in piglets. Methods Seventy-two piglets (36 barrows and 36 gilts) weaned at 28±2 d and initial body weight of 7.17±1.07 kg were allocated to 3 treatments in a randomized complete block design with 8 replicates per treatment and 3 animals per experimental unit. Treatments were composed of NC, negative control: basal diet without additives; PC, positive control: basal diet + 40 mg/kg of colistin sulfate; or BT, basal diet + calcium butyrate + tannin extract. The butyrate and tannin inclusion levels were 0.15% in the pre-starter phase and 0.075% in the starter phase. Incidence of diarrhea was monitored daily, and on d 14 and 35 of experiment, 1 animal from each experimental unit was slaughtered to collect intestinal samples. Results No significant differences were observed for growth performance. The butyrate- and tannin-based additive resulted in reduced (p
- Published
- 2022
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