1. Gonococci resistant to current antimicrobial management standards: a new threat to global public health.
- Author
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Dos Santos TF, Goveia MR, Moraes GM, Tavares MA, Davalos SR, Campos CB, de Oliveira FA, Benitez DF, Tavares MB, Colli EH, Pinheiro ME, Rodrigues BDR, Neto CD, and Ribeiro RS
- Subjects
- Anti-Bacterial Agents pharmacology, Anti-Bacterial Agents therapeutic use, Ceftriaxone pharmacology, Ceftriaxone therapeutic use, Drug Resistance, Bacterial, Humans, Microbial Sensitivity Tests, Neisseria gonorrhoeae, Public Health, Anti-Infective Agents pharmacology, Gonorrhea drug therapy, Gonorrhea microbiology
- Abstract
Gonorrhea is the second most common sexually transmitted bacterial infection on the planet and is caused by a Gram-negative cocco, Neisseria gonorrhoeae . Currently, the preferred regimen for the management of this disease in Brazil is a combination of antimicrobials, in this case, ceftriaxone and azithromycin. However, over time, the gonococcus developed a decrease in susceptibility to the regimen used, which resulted in frank resistance to antimicrobials, progressively reducing the therapeutic options available. Thus, the study presented here aims to analyze and discuss the current scenario of resistance of N. gonorrhoeae to the antimicrobials used to date, to encourage discussion on the subject in the academic environment. For this purpose, 47 articles indexed in the Bireme, PubMed, Scielo and UpToDate platforms were selected.
- Published
- 2022
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