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13 results on '"Bouayadi, Ouardia"'

2. Monoclonal plasma cell dyscrasia: immunochemical and etiological parameters of 151 cases living in the Eastern area of Morocco

Author

Choukri Mohammed, Azghar Ali, El Malki Jalila, Bouayadi Ouardia, Bensalah Mohammed, Noussaiba Benhamzaa, and Aarab Adnane

Subjects
Pathology, medicine.medical_specialty, Heterogeneous group, business.industry, Plasma cell dyscrasia, Monoclonal immunoglobulin, medicine.disease, medicine.anatomical_structure, Monoclonal, otorhinolaryngologic diseases, medicine, Etiology, Bone marrow, business
Abstract

Plasma cell dyscrasia (PCD) are a heterogeneous group of diseases characterized by the expansion of monoclonal bone marrow plasma cells that produce a monoclonal immunoglobulin (M-component).

Published
2021
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3. WITHDRAWN: Gemella haemolysans Brain Abscess: A Case Report

Author

Maleb, Adil, Bouayadi, Ouardia, Elmalki, Jalila, Lamrabat, Somiya, Rifai, Safaa, El Idrissi, Fahd El Ayoubi, Ghailan, Mohammed Rachid, Raouzi, Nabil, Oulali, Noureddine, Moufid, Fayçal, Lahlou, Yassine Ben, Frikh, Mohammed, Lemnouer, Abdelhay, and Elouennass, Mostafa

Published
2018
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4. Gemella haemolysans Brain Abscess

Author

Maleb, Adil, primary, Bouayadi, Ouardia, additional, Elmalki, Jalila, additional, Lamrabat, Somiya, additional, Rifai, Safaa, additional, El Ayoubi El Idrissi, Fahd, additional, Ghailan, Mohammed Rachid, additional, Raouzi, Nabil, additional, Oulali, Noureddine, additional, Moufid, Fayçal, additional, Lahlou, Yassine Ben, additional, Frikh, Mohammed, additional, Lemnouer, Abdelhay, additional, and Elouennass, Mostafa, additional

Published
2019
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10. [Serum protein electrophoresis: study of 410 electrophoretic profiles].

Author

Bouayadi O, Bensalah M, Rahmani N, Assoufi S, and Choukri M

Subjects
Adolescent, Adult, Agammaglobulinemia diagnosis, Agammaglobulinemia epidemiology, Aged, Aged, 80 and over, Child, Child, Preschool, Cross-Sectional Studies, Female, Hospitals, University, Humans, Hypoalbuminemia epidemiology, Infant, Inflammation epidemiology, Male, Middle Aged, Nephrotic Syndrome diagnosis, Nephrotic Syndrome epidemiology, Paraproteinemias epidemiology, Young Adult, Blood Protein Electrophoresis methods, Hypoalbuminemia diagnosis, Inflammation diagnosis, Paraproteinemias diagnosis
Abstract

Serum protein electrophoresis (SPE) is a routine analysis in the daily practice of a medical biology laboratory. This study aimed to analyze the different electrophoretic profiles seen in our current practice. We conducted a cross-sectional study of 410 serum samples collected during the routine analyses in the Laboratory of Biochemistry at the University Hospital Mohammed VI in Oujda. Serum protein electrophoresis was performed using automated instrument CAPILLARYS 2 FLEX-PIERCING, SEBIA. 241 sera from women and 169 sera from men were collected. Patients were aged between 1-91 years, with an average age of 49 years; 19.5% of SPEs were normal, hypoalbuminemia was found in 34% of cases, chronic inflammatory syndrome in 19.5% of cases, nephrotic syndrome in 2% of cases, 5.8% of our patients had betagamma block, hypogammaglobulinemia was found in 8.5% of cases and 29 monoclonal peaks were noted, bisalbuminemia was found in 2 patients. Out of 410 collections: 92 immunofixations were performed, of whom 23 were positive (showing monoclonal gammopathy). This study highlights the variability in prescribing serum protein electrophoresis as well as the importance of clinical data for a better interpretation., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts.

Published
2019
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11. A Rare Case of Non-Secretory Multiple Myeloma: A Case Report and Literature Review.

Author

Bensalah M, Lamrabat S, Lyagoubi A, Aarab A, Bouayadi O, and Seddik R

Abstract

Non-secretory myeloma (NSM) is a rare form of myeloma. It is defined as monoclonal plasmocytic proliferation of the bone marrow with the same clinical and radiological manifestations of myeloma. However, plasma cells are unable to secrete immunoglobulin (serum and urinary electrophoresis are negative and free light chain measurement is unquantifiable). This variant of multiple myeloma (MM) usually poses a diagnostic challenge to the biologist and clinician. We report a rare case of non-secretory myeloma in a 76-year-old patient who was diagnosed at the Mohammed V University Hospital Center in Oujda, Morocco.

Published
2019

12. Gaucher Disease: An Underdiagnosed Pathology in the Eastern Moroccan Population.

Author

Bouayadi O, Lyagoubi A, Aarab A, Lamrabat S, Berhili A, Bensalah M, and Seddik R

Abstract

Gaucher disease (GD) is a lysosomal storage disease. It corresponds to a congenital deficit in β-glucocerebrosidase. This pathology should be considered in the presence of unexplained splenomegaly, with or without signs of haemorrhage, skeletal manifestations or hepatomegaly. The diagnosis is based on the measurement of the β-glucocerebrosidase activity but the preanalytical process should be respected in order to avoid the under-diagnosis of this disorder and the delay of its management. We report two cases of Gaucher disease collected at Mohammed VI University Hospital and Al Farabi regional hospital in Oujda. We have emphasized the need for a reference center for overload diseases.

Published
2019

13. [Comparative study of the serum measurement of PTH on Roche Cobas e411 ® versus the Abbott Architect ci8200 ® ].

Author

Bensalah M, Bouayadi O, Rahmani N, Lyagoubi A, Lamrabat S, and Choukri M

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Blood Specimen Collection standards, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Immunoassay instrumentation, Immunoassay methods, Infant, Infant, Newborn, Male, Middle Aged, Parathyroid Hormone analysis, Radioimmunoassay instrumentation, Radioimmunoassay methods, Reproducibility of Results, Young Adult, Blood Chemical Analysis instrumentation, Blood Chemical Analysis methods, Parathyroid Hormone blood
Abstract

Parathormone (PTH) is the main hormone of phosphocalcic homeostasis. It is synthesized and secreted by the parathyroid glands. PTH has become a routine test in the medical biology laboratory. However, its measurement presents analytical difficulties with the various marketed kits. The aim of this work is to present the results of a comparative study between the PTH measurment on Abbott architect ci8200 and on Roche's Cobas e411 automaton. It is a prospective study carried out for 252 hospitalized patients in the various departments of the University Hospital Center Mohammed VI of Oujda. The "intact" PTH tests were performed on two automata: Abbott Architect ci8200 and Roche Cobas e411. The first uses chemiluminescent microparticle immunoassay. The second uses electrochemiluminiscence sandwich enzyme immunoassay. The agreement of the results between the different techniques was evaluated using the Bland-Altman difference diagram and the Passing-Bablok and Deming regression line (MedCalc software version 14.8.1.0 ® ). By analyzing the diagram of Bland-Altman, we note that the average bias between both methods is of the order of 193.9 pg/mL. As for the equation of the right of Passing-Bablok, it is: Y(Architect) = 3.11 X (Cobas) - 12.26. In conclusion, our study shows a great discrepancy between the results of the PTH assay on the Architect ci8200 versus the Cobas e411, hence the biologist's indisputable role in the control and evaluation of the kits marketed through the various validation tests.

Published
2018
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