The world is in crisis, locked in the throes of an unprecedented economic lockdown as the coronavirus, in the specific form of COVID-19, takes its toll on societies around the world. At the time of this writing, countries have shut down vital parts of their administrations, education sectors, and economic activities. Whole industries, including hospitality and air transport, have essentially stopped functioning; the closing of national borders limits free movement to a minimum anyway. The related humanitarian crisis came as a shock to many people, and new restrictions together with enormous challenges represent a discontinuity, breaking from the past reality. Furthermore, this crisis features immense volatility, making it nearly impossible for people to imagine all the potential, invisible dangers and visible changes. Simply put, we are living in truly disruptive times. But the notion of disruption is not new; it has long appeared in business discussions. Executives have tried to understand, be prepared for, and even initiate disruption (Markides, 2006). Not every disruptive idea follows the trajectory predicted by Clayton Christensen (1997), but substantial energy has gone into preparing for business model disruptions along the lines that he outlined (Markides, 2006). For example, executives have tried to anticipate disruptions due to digital advances (e.g., Ritter & Pedersen, 2020), platform business models (e.g., Cusumano & Gower, 2002), or new market orientations (e.g., Kumar, Scheer, & Kotler, 2000). Yet these types of preemptive measures were made obsolete by the truly unexpected and far-reaching disruptions created by the highly contagious virus, which has already prompted a greater downturn than might have been caused by any alternative business models, innovative technologies, new forms of working, or the like. At the same time, another important difference pertains to predicted durations. Digitalization, the Internet, and connectivity through the Internet-of-Things have prompted shifts that remain relevant. Although the immediate crisis created by COVID-19 may have mainly a temporary effect, followed by a partial return to “normal” times, its broader impact may be persistent and significant, leading to the “new normal” of a post-corona world. In this shift, health care service preparedness must be rethought, supply chain risk needs to be redefined, online meetings likely will become the norm, and virtual teaching may represent a critical channel for education. In this sense, the virus crisis represents a temporary discontinuity, after which some aspects will return to their prior status, even as others might be changed forever. Furthermore, the crisis could have negative consequences for firms, if not managed appropriately (Coombs, 2007), while also offering an opportunity, as long as decision makers perceive it accurately (Brockner & James, 2008). For example, environmental crises often have fueled human development, throughout history, revealing how they can create opportunities if exploited and managed wisely (Bernstein, 1996). Some firms that perform well during the crisis may gain new customers, but other firms appear destined to fail. How firms respond and react during the crisis arguably will determine, at least partially, whether they thrive. With some notable exceptions (e.g., Andersson & Mattson, 2010; Hermes & Mainela, 2014; Naidoo, 2010), business-to-business marketing has not, remarkably, focused much on crisis management. Yet business-to-business firms have encountered a multitude of recent crises, from the dot.com bubble to the financial crisis to 9/11 to SARS to Brexit. Furthermore, the COVID-19 crisis is unprecedented, to the extent that we lack any established knowledge to comprehend its consequences fully. Similar to most sectors in society, business-to-business marketers lack relevant guidance for meeting the enormous challenges they face. Both marketing in general and Industrial Marketing Management in particular have a long-standing tradition of conducting research with and for practitioners, and accordingly, we believe the business-to-business academic marketing community is uniquely well qualified to address these issues and concerns, using theory-based reasoning to help support executives' efforts to manage their firms through the COVID-19 crisis and beyond. Against this backdrop, we prepare this special issue on managing crises by establishing its strong focus on the managerial implications for business-to-business firms, as derived from business-to-business marketing research. We have two primary aims with this special issue: First, we seek to offer business-to-business marketing practitioners theory-based insights and practical implications. The business-to-business marketing community can and should bridge the rigor–relevance divide, by providing research-based, practical implications that rest on a strong foundation of theory. In accordance with this aim, the articles in this issue can be purposefully shorter than typical Industrial Marketing Management articles, written mainly to argue for practical implications rather than make novel theoretical contributions. Second, we emphasize the continuing need for crisis management research from a business-to-business marketing perspective. Such a research tradition should prove highly relevant for practitioners facing crises, now and in the future. In the next section, we thus define a crisis and explicate its different phases. Following a discussion of crisis management in general, we summarize some crisis management contributions in Industrial Marketing Management. We also zoom in on some selected theories and their implications for business-to-business marketers during the COVID-19 era, which in turn suggest areas for further research. Thus, this editorial offers a terminology for discussing crisis and crisis management, describes the current state-of-the-art of business-to-business crisis management literature, and offers a research agenda.