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156 results on '"Cavallesco, Giorgio"'

1. The Overweight Paradox: Impact of Body Mass Index on Patients Undergoing VATS Lobectomy or Segmentectomy

Author

Parini, Sara, Azzolina, Danila, Massera, Fabio, Mastromarino, Maria Giovanna, Papalia, Esther, Baietto, Guido, Curcio, Carlo, Crisci, Roberto, Rena, Ottavio, Alloisio, Marco, Amore, Dario, Ampollini, Luca, Ardò, Nicoletta, Argnani, Desideria, Baisi, Alessandro, Bandiera, Alessandro, Benato, Cristiano, Benvenuti, Mauro Roberto, Bertani, Alessandro, Bortolotti, Luigi, Bottoni, Edoardo, Breda, Cristiano, Camplese, Pierpaolo, Carbognani, Paolo, Cardillo, Giuseppe, Carleo, Francesco, Cavallesco, Giorgio, Cherchi, Roberto, De Palma, Angela, Dell'Amore, Andrea, Della Beffa, Vittorio, Divisi, Duilio, Dolci, Giampiero, Droghetti, Andrea, Ferrari, Paolo, Fontana, Diego, Gasparri, Roberto, Gavezzoli, Diego, Ghisalberti, Marco, Giovanardi, Michele, Gonfiotti, Alessandro, Guerrera, Francesco, Imperatori, Andrea, Infante, Maurizio, Lausi, Paolo, Lo Giudice, Fabio, Londero, Francesco, Lopez, Camillo, Mancuso, Maurizio, Maniscalco, Pio, Margaritora, Stefano, Marulli, Giuseppe, Mazza, Federico, Meacci, Elisa, Melloni, Giulio, Morelli, Angelo, Mucilli, Felice, Natali, Pamela, Negri, Giampiero, Nicotra, Samuele, Nosotti, Mario, Paladini, Piero, Pariscenti, Gianluca, Perkmann, Reinhold, Pernazza, Fausto, Pirondini, Emanuele, Puma, Francesco, Raveglia, Federico, Refai, Majed, Rinaldo, Alessandro, Risso, Carlo, Rizzardi, Giovanna, Rotolo, Nicola, Scarci, Marco, Solli, Piergiorgio, Sollitto, Francesco, Spaggiari, Lorenzo, Stefani, Alessandro, Stella, Franco, Surrente, Corrado, Tancredi, Giorgia, Terzi, Alberto, Torre, Massimo, Tosi, Davide, Vinci, Damiano, Viti, Andrea, Voltolini, Luca, and Zaraca, Francesco

Published
2023
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2. Emergency Video-Assisted Thoracoscopy in the Elderly

Author

Tamburini, Nicola, D’Urbano, Francesco, Maniscalco, Pio, Quarantotto, Francesco, Bagolini, Francesco, Bertani, Alessandro, Cavallesco, Giorgio, Agresta, Ferdinando, editor, Podda, Mauro, editor, Campanile, Fabio Cesare, editor, Bergamini, Carlo, editor, and Anania, Gabriele, editor

Published
2021
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5. Post-operative outcomes and quality of life assessment after thoracoscopic lobectomy for Non-small-cell lung cancer in octogenarians: Analysis from a national database

Author

Alloisio, Marco, Amore, Dario, Ampollini, Luca, Andreetti, Claudio, Argnani, Desideria, Baietto, Guido, Bandiera, Alessandro, Benato, Cristiano, Benvenuti, Mauro Roberto, Bertani, Alessandro, Bertolaccini, Luca, Bortolotti, Luigi, Bottoni, Edoardo, Breda, Cristiano, Camplese, Pierpaolo, Carbognani, Paolo, Cardillo, Giuseppe, Casadio, Caterina, Cavallesco, Giorgio, Cherchi, Roberto, Crisci, Roberto, Curcio, Carlo, Dell’Amore, Andrea, Della Beffa, Vittorio, Dolci, Giampiero, Droghetti, Andrea, Ferrari, Paolo A., Fontana, Diego, Gargiulo, Gaetano, Gasparri, Roberto, Gavezzoli, Diego, Ghisalberti, Marco, Giovanardi, Michele, Gonfiotti, Alessandro, Guerrera, Francesco, Imperatori, Andrea, Infante, Maurizio, Iurilli, Luciano, Lausi, Paolo, Lo Giudice, Fabio, Londero, Francesco, Luzzi, Luca, Lopez, Camillo, Mancuso, Maurizio, Maniscalco, Pio, Margaritora, Stefano, Meacci, Elisa, Melloni, Giulio, Morelli, Angelo, Mucilli, Felice, Natali, Pamela, Negri, Giampiero, Nicotra, Samuele, Nosotti, Mario, Pariscenti, Gianluca, Perkmann, Reinhold, Pernazza, Fausto, Pirondini, Emanuele, Poggi, Camilla, Puma, Francesco, Refai, Majed, Rinaldo, Alessandro, Rizzardi, Giovanna, Rosso, Lorenzo, Rotolo, Nicola, Russo, Emanuele, Sabbatini, Armando, Scarci, Marco, Spaggiari, Lorenzo, Stefani, Alessandro, Solli, Piergiorgio, Surrente, Corrado, Terzi, Alberto, Torre, Massimo, Vinci, Damiano, Viti, Andrea, Voltolini, Luca, Zaccagna, Gino, Zaraca, Francesco, Bongiolatti, Stefano, and Borgianni, Sara

Published
2021
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6. Association of the Extent of Resection with Survival in Multiple Primary Lung Cancer: A Systematic Review

Author

Tamburini, Nicola, Bombardini, Cristina, Chiappetta, Marco, Maniscalco, Pio, Valpiani, Giorgia, Cesario, Alfredo, Cirocchi, Roberto, Anania, Gabriele, Stefanelli, Antonio, Cavallesco, Giorgio, Margaritora, Stefano, Lococo, Filippo, Cesario, Alfredo (ORCID:0000-0003-4687-0709), Margaritora, Stefano (ORCID:0000-0002-9796-760X), Lococo, Filippo (ORCID:0000-0002-9383-5554), Tamburini, Nicola, Bombardini, Cristina, Chiappetta, Marco, Maniscalco, Pio, Valpiani, Giorgia, Cesario, Alfredo, Cirocchi, Roberto, Anania, Gabriele, Stefanelli, Antonio, Cavallesco, Giorgio, Margaritora, Stefano, Lococo, Filippo, Cesario, Alfredo (ORCID:0000-0003-4687-0709), Margaritora, Stefano (ORCID:0000-0002-9796-760X), and Lococo, Filippo (ORCID:0000-0002-9383-5554)

Abstract

Background The incidence of synchronous multiple primary lung cancer (SMPLC) has progressively increased, due to recent advances in imaging. To date, no guidelines defining recommendations for patients' selection and no standard treatment of cases with SMPLC have been defined. The primary aim of this systematic review was to assess survival among patients treated with lobectomy or sublobar resection MPLC. Methods Comprehensive literature search of Medline, the Cochrane Library, reference lists, and ongoing studies was performed according to a prospectively registered design (PROSPERO: CRD42019115487). All studies published between 1998 and December 2020 that examined treatments with lobectomy compared to sublobar resection were included. Two double-blind investigators independently selected articles. Primary outcomes were to assess the 5-year overall survival (OS) rate among patients treated with lobectomy or sublobar resection and the impact of lymph node status on 5-year OS and 5-year disease-free survival in patients with MPLC. Results The search yielded 424 articles; 4 observational studies met the inclusion criteria and collectively evaluated 298 patients with a mean age ranging from 61.5 to 67 years. A total of 112 patients were treated for bilateral synchronous tumors and 186 patients for unilateral multiple synchronous tumors. All included studies showed that the type of resection, lobectomy or limited resection, had no significant impact on survival. Conclusion Limited resection is a valuable treatment option for MPLC. However, the clinical level of evidence of the studies found is low and randomized studies are needed to clarify the extent of resection in MPLC.

Published
2023

7. Air leak and intraoperative bleeding in thoracic surgery: a Delphi consensus among the members of Italian society of thoracic surgery

Author

Cardillo, Giuseppe, primary, Nosotti, Mario, additional, Scarci, Marco, additional, Torre, Massimo, additional, Alloisio, Marco, additional, Benvenuti, Mauro Roberto, additional, Bertani, Alessandro, additional, Cagini, Lucio, additional, Casablanca, Giuseppe, additional, Cavallesco, Giorgio, additional, Cherchi, Roberto, additional, Crucitti, Pierfilippo, additional, Curcio, Carlo, additional, Denegri, Andrea, additional, Droghetti, Andrea, additional, Guggino, Gianluca, additional, Imperatori, Andrea, additional, Infante, Maurizio Valentino, additional, Lucchi, Marco, additional, Macrì, Paolo, additional, Marulli, Giuseppe, additional, Melloni, Giulio, additional, Paci, Massimiliano, additional, Paladini, Piero, additional, Pariscenti, Gian Luca, additional, Potenza, Enrico, additional, Rea, Federico, additional, Refai, Majed, additional, Rena, Ottavio, additional, Ricciardi, Sara, additional, Rusca, Michele, additional, Sollitto, Francesco, additional, Taurchini, Marco, additional, Terzi, Alberto, additional, Voltolini, Luca, additional, and Crisci, Roberto, additional

Published
2022
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8. Unilateral Thoracoscopic Thymectomy for Thymoma: Does Side Matter? A Single Institutional Experience.

Author

Tamburini, Nicola, D'Urbano, Francesco, Bagolini, Francesco, Trapella, Giulia Salerno, Quarantotto, Francesco, Cavallesco, Giorgio, and Maniscalco, Pio

Subjects
THYMECTOMY, CHEST endoscopic surgery, VIDEO-assisted thoracic surgery, THYMOMA, SURGICAL blood loss, SURGICAL complications, PROGRESSION-free survival
Abstract

Background Thoracoscopic thymectomy is increasingly performed for the treatment of early stage thymoma. It is characterized by shorter postoperative hospital stay, decreased intraoperative blood loss, and fewer complications compared with transsternal thymectomy. Unilateral video-assisted thoracic surgery (VATS) thymectomy can be easily performed from either side of the thorax, because thymus is located in the middle of mediastinum. However, the side that provides better outcomes remains controversial. The purpose of this study was to compare the efficacy of right and left approaches in performing unilateral thoracoscopic thymectomy for thymoma. Methods Consecutive patients affected by thymoma who underwent VATS thymectomy on either side between February 2001 and March 2020 were enrolled in the study. Clinicopathologic, surgical, and oncological outcomes were retrospectively analyzed and compared among the two surgical approaches. Results Unilateral VATS approaches were performed on 29 patients: 12 (41%) on the left side and 17 (59%) on the right side. The mean age was 63.1 ± 11.3 years and the female/male ratio was 1.73:1. The mean operative time and the hospital stay for the left-side VATS and right-side VATS groups were, respectively, 168 ± 49.5 versus 171 ± 47.9 minutes (p = 0.9) and 3 ± 1.03 days versus 3.65 ± 1.93 days (p = 0.7). Postoperative complications occurred in one patient (3%) for left-side VATS group and one patient (3%) for right-side VATS. The 5-year disease-free survival was comparable between two groups (p = 0.74). Conclusion Unilateral VATS thymectomy in patients with thymoma can be safely and effectively performed by experienced surgeons in either side of the thorax with equivalent oncological outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Inflammatory Microenvironment in Early Non-Small Cell Lung Cancer: Exploring the Predictive Value of Radiomics

Author

Perrone, Mariasole, primary, Raimondi, Edoardo, additional, Costa, Matilde, additional, Rasetto, Gianluca, additional, Rizzati, Roberto, additional, Lanza, Giovanni, additional, Gafà, Roberta, additional, Cavallesco, Giorgio, additional, Tamburini, Nicola, additional, Maniscalco, Pio, additional, Mantovani, Maria Cristina, additional, Tebano, Umberto, additional, Coeli, Manuela, additional, Missiroli, Sonia, additional, Tilli, Massimo, additional, Pinton, Paolo, additional, Giorgi, Carlotta, additional, and Fiorica, Francesco, additional

Published
2022
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14. Impact of COVID-19 on surgical activities and personnel: lessons for the future

Author

RUBBINI, Michele, primary, GRECO, Pantaleo, additional, MANSERVIGI, Margherita, additional, MARTINELLO, Ruby, additional, GASBARRO, Vincenzo, additional, PICCOLO, Elisa, additional, OCCHIONORELLI, Savino, additional, LACAVALLA, Domenico, additional, MASSARI, Leo, additional, CARUSO, Gaetano, additional, CALDARIA, Antonio, additional, PERRI, Paolo, additional, SALGARI, Niccolò, additional, CAVALLESCO, Giorgio N., additional, ANANIA, Gabriele, additional, CHIOZZA, Matteo, additional, CARCOFORO, Paolo, additional, MARUCA, Alberto M., additional, CAVALLO, Michele A., additional, SCERRATI, Alba, additional, CAPONE, Gennaro, additional, FEO, Carlo V., additional, FABBRI, Nicolò, additional, FAZZIN, Marta, additional, and FORINI, Maria E., additional

Published
2022
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15. Association of the Extent of Resection with Survival in Multiple Primary Lung Cancer: A Systematic Review

Author

Tamburini, Nicola, additional, Bombardini, Cristina, additional, Chiappetta, Marco, additional, Maniscalco, Pio, additional, Valpiani, Giorgia, additional, Cesario, Alfredo, additional, Cirocchi, Roberto, additional, Anania, Gabriele, additional, Stefanelli, Antonio, additional, Cavallesco, Giorgio, additional, Margaritora, Stefano, additional, and Lococo, Filippo, additional

Published
2022
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16. The Overweight Paradox: Impact of Body Mass Index on Patients Undergoing VATS Lobectomy or Segmentectomy

Author

Parini, Sara, primary, Azzolina, Danila, additional, Massera, Fabio, additional, Mastromarino, Maria Giovanna, additional, Papalia, Esther, additional, Baietto, Guido, additional, Curcio, Carlo, additional, Crisci, Roberto, additional, Rena, Ottavio, additional, Alloisio, Marco, additional, Amore, Dario, additional, Ampollini, Luca, additional, Ardò, Nicoletta, additional, Argnani, Desideria, additional, Baisi, Alessandro, additional, Bandiera, Alessandro, additional, Benato, Cristiano, additional, Benvenuti, Mauro Roberto, additional, Bertani, Alessandro, additional, Bortolotti, Luigi, additional, Bottoni, Edoardo, additional, Breda, Cristiano, additional, Camplese, Pierpaolo, additional, Carbognani, Paolo, additional, Cardillo, Giuseppe, additional, Carleo, Francesco, additional, Cavallesco, Giorgio, additional, Cherchi, Roberto, additional, De Palma, Angela, additional, Dell'Amore, Andrea, additional, Della Beffa, Vittorio, additional, Divisi, Duilio, additional, Dolci, Giampiero, additional, Droghetti, Andrea, additional, Ferrari, Paolo, additional, Fontana, Diego, additional, Gasparri, Roberto, additional, Gavezzoli, Diego, additional, Ghisalberti, Marco, additional, Giovanardi, Michele, additional, Gonfiotti, Alessandro, additional, Guerrera, Francesco, additional, Imperatori, Andrea, additional, Infante, Maurizio, additional, Lausi, Paolo, additional, Lo Giudice, Fabio, additional, Londero, Francesco, additional, Lopez, Camillo, additional, Mancuso, Maurizio, additional, Maniscalco, Pio, additional, Margaritora, Stefano, additional, Marulli, Giuseppe, additional, Mazza, Federico, additional, Meacci, Elisa, additional, Melloni, Giulio, additional, Morelli, Angelo, additional, Mucilli, Felice, additional, Natali, Pamela, additional, Negri, Giampiero, additional, Nicotra, Samuele, additional, Nosotti, Mario, additional, Paladini, Piero, additional, Pariscenti, Gianluca, additional, Perkmann, Reinhold, additional, Pernazza, Fausto, additional, Pirondini, Emanuele, additional, Puma, Francesco, additional, Raveglia, Federico, additional, Refai, Majed, additional, Rinaldo, Alessandro, additional, Risso, Carlo, additional, Rizzardi, Giovanna, additional, Rotolo, Nicola, additional, Scarci, Marco, additional, Solli, Piergiorgio, additional, Sollitto, Francesco, additional, Spaggiari, Lorenzo, additional, Stefani, Alessandro, additional, Stella, Franco, additional, Surrente, Corrado, additional, Tancredi, Giorgia, additional, Terzi, Alberto, additional, Torre, Massimo, additional, Tosi, Davide, additional, Vinci, Damiano, additional, Viti, Andrea, additional, Voltolini, Luca, additional, and Zaraca, Francesco, additional

Published
2022
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19. Factors Associated with Early Discharge after Thoracoscopic Lobectomy: Results from the Italian VATS Group Registry.

Author

Maniscalco, Pio, Tamburini, Nicola, Fabbri, Nicolò, Quarantotto, Francesco, Rizzardi, Giovanna, Amore, Dario, Lopez, Camillo, Crisci, Roberto, Spaggiari, Lorenzo, Valpiani, Giorgia, Bertolaccini, Luca, and Cavallesco, Giorgio

Subjects
LOBECTOMY (Lung surgery), LOGISTIC regression analysis, PAIN management, FACTOR analysis, TEMPORAL lobectomy, JUDGMENT (Psychology)
Abstract

Objective. There are limited data for estimating the risk of early discharge following thoracoscopic lobectomy. The objective was to identify the factors associated with a short length of stay and verify the influence of these variables in uncomplicated patients. Methods. We reviewed all lobectomies reported to the Italian VATS Group between January 2014 and January 2020. Patients and perioperative characteristics were divided into two subgroups based on whether or not they met the target duration of stay (≤ or >4 days). The association between preoperative and intraoperative variables and postoperative length of stay (LOS) ≤4 days was assessed using a stepwise multivariable logistic regression analysis to identify factors independently associated with LOS and factors related to LOS in uncomplicated cases. Results. Among 10,240 cases who underwent thoracoscopic lobectomy, 37.6% had a hospital stay ≤4 days. Variables associated with LOS included age, hospital surgical volume, Diffusion Lung CO % (81 [69–94] vs. 85 [73–98]), Forced Expiratory Volume (FEV1) % (92 [79–106] vs. 96 [82–109]), operative time (180 [141–230] vs. 160 [125–195]), uniportal approach (571 [9%] vs. 713 [18.5%]), bioenergy sealer use, and pain control through intercostal block or opioids (p < 0.001). Except for FEV1 and blood loss, all other factors emerged significantly associated with LOS when the analysis was limited to uncomplicated patients. Conclusions. Demographic, clinical, and surgical variables are associated with early discharge after thoracoscopic lobectomy. This study indicates that these characteristics are associated with early discharge. This result can be used in association with clinical judgment to identify appropriate patients for fast-track protocols. [ABSTRACT FROM AUTHOR]

Published
2022
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22. Standardized uptake value and radiological density attenuation as predictive and prognostic factors in patients with solitary pulmonary nodules: our experience on 1,592 patients

Author

Divisi, Duilio, Barone, Mirko, Bertolaccini, Luca, Rocco, Gaetano, Solli, Piergiorgio, Crisci, Roberto, Italian Vats Group, Ampollini, Luca, Alloisio, Marco, Andreetti, Claudio, Amore, Dario, Baietto, Guido, Bandiera, Alessandro, Benato, Cristiano, Benetti, Diego, Benvenuti, Mauro, Bertani, Alessandro, Bortolotti, Luigi, Bottoni, Edoardo, Camplese, Pierpaolo, Carbognani, Paolo, Cardillo, Giuseppe, Carleo, Francesco, Casadio, Caterina, Cavallesco, Giorgio, Curcio, Carlo, Denegri, Andrea, Di Rienzo, Gaetano, Dolci, Giampiero, Droghetti, Andrea, Gasparri, Roberto, Ghisalberti, Marco, Gonfiotti, Alessandro, Guerrera, Francesco, Imperatori, Andrea, Infante, Maurizio, Lausi, Paolo, Londero, Francesco, Lopez, Camillo, Luzzi, Luca, Maineri, Paola, Maniscalco, Pio, Marulli, Giuseppe, Monteverde, Marco, Morelli, Angelo, Mucilli, Felice, Natali, Pamela, Negri, Giampiero, Nicotra, Samuele, Nosotti, Mario, Perkmann, Reinhold, Poggi, Camilla, Puma, Francesco, Refai, Mayed, Rinaldo, Alessandro, Rizzardi, Giovanna, Rosso, Lorenzo, Rotolo, Nicola, Russo, Emanuele, Sabatini, Armando, Spaggiari, Lorenzo, Stefani, Alessandro, Stella, Franco, Terzi, Alberto, Torre, Massimo, Vinci, Damiano, Viti, Andrea, Voltolini, Luca, Zaraca, Francesco, Divisi, Duilio, Barone, Mirko, Bertolaccini, Luca, Rocco, Gaetano, Solli, Piergiorgio, Crisci, Roberto, Italian VATS, Group, Negri, G, Ampollini, Luca, Alloisio, Marco, Andreetti, Claudio, Amore, Dario, Baietto, Guido, Bandiera, Alessandro, Benato, Cristiano, Benetti, Diego, Benvenuti, Mauro, Bertani, Alessandro, Bortolotti, Luigi, Bottoni, Edoardo, Camplese, Pierpaolo, Carbognani, Paolo, Cardillo, Giuseppe, Carleo, Francesco, Casadio, Caterina, Cavallesco, Giorgio, Curcio, Carlo, Denegri, Andrea, Di Rienzo, Gaetano, Dolci, Giampiero, Droghetti, Andrea, Gasparri, Roberto, Ghisalberti, Marco, Gonfiotti, Alessandro, Guerrera, Francesco, Imperatori, Andrea, Infante, Maurizio, Lausi, Paolo, Londero, Francesco, Lopez, Camillo, Luzzi, Luca, Maineri, Paola, Maniscalco, Pio, Marulli, Giuseppe, Monteverde, Marco, Morelli, Angelo, Mucilli, Felice, Natali, Pamela, Negri, Giampiero, Nicotra, Samuele, Nosotti, Mario, Perkmann, Reinhold, Poggi, Camilla, Puma, Francesco, Refai, Mayed, Rinaldo, Alessandro, Rizzardi, Giovanna, Rosso, Lorenzo, Rotolo, Nicola, Russo, Emanuele, Sabatini, Armando, Spaggiari, Lorenzo, Stefani, Alessandro, Stella, Franco, Terzi, Alberto, Torre, Massimo, Vinci, Damiano, Viti, Andrea, Voltolini, Luca, and Zaraca, Francesco

Subjects
Lung adenocarcinoma, Pulmonary and Respiratory Medicine, medicine.medical_specialty, VATS lobectomy, Standardized uptake value, Malignancy, Ground-glass opacity, NO, 030218 nuclear medicine & medical imaging, Maximum standardized uptake value, 03 medical and health sciences, 0302 clinical medicine, ground glass opacities, Solitary pulmonary nodule (SPN), maximum standardized uptake value, lymph node metastases, lung adenocarcinoma, Lymph node metastase, medicine, Ground glass opacities, Lymph node metastases, Lung cancer, Lymph node, business.industry, Ground glass opacitie, Nodule (medicine), medicine.disease, Primary tumor, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Original Article, Radiology, medicine.symptom, business
Abstract

Background: Multislice computed tomography (MSCT) increased detection of solitary pulmonary nodules (SPNs), changing the management based on radiological and clinical factors. When 18-fluorine fluorodeoxyglucose positron emission tomography combined with computed tomography ( 18 F-FDG-PET/CT) was considered for the evaluation of nodules, the maximum standardized uptake value (SUVmax) more than 2.5 is used frequently as a cut off for malignancy. The purpose of this study is to evaluate SUVmax PET/CT and pulmonary attenuation patterns at MSCT in patients with SPN according to morphological and pathological characteristics of the lesion. Methods: A retrospective study on 1,592 SPN patients was carried out following approval by the Italian Registry of VATS Lobectomies. Results: All patients underwent VATS lobectomy. On histologic examination, 98.1% had primary or second metachronous primary lung cancers. In addition, 10.7% presented occult lymph node metastases (pN1 or pN2) on histological examination. Nodule attenuation on CT was associated with the histology of the lesion (p= 0.030); in particular, pure ground glass opacities (pGGOs) and partially solid nodules were related to adenocarcinomatous histotypes. Conversely, a significant relationship between SUVmax and age, nodule size, pathological node status (pN) was found (P=0.007, P=0.000 and P=0.002 respectively). Conclusions: Nodule attenuation can predict the histology of the lesion whereas SUVmax may relate to the propensity to lymph node metastases.

Published
2017
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23. Post-operative outcomes and quality of life assessment after thoracoscopic lobectomy for Non-small-cell lung cancer in octogenarians: Analysis from a national database

Author

Bongiolatti, Stefano, primary, Gonfiotti, Alessandro, additional, Borgianni, Sara, additional, Crisci, Roberto, additional, Curcio, Carlo, additional, Voltolini, Luca, additional, Alloisio, Marco, additional, Amore, Dario, additional, Ampollini, Luca, additional, Andreetti, Claudio, additional, Argnani, Desideria, additional, Baietto, Guido, additional, Bandiera, Alessandro, additional, Benato, Cristiano, additional, Benvenuti, Mauro Roberto, additional, Bertani, Alessandro, additional, Bertolaccini, Luca, additional, Bortolotti, Luigi, additional, Bottoni, Edoardo, additional, Breda, Cristiano, additional, Camplese, Pierpaolo, additional, Carbognani, Paolo, additional, Cardillo, Giuseppe, additional, Casadio, Caterina, additional, Cavallesco, Giorgio, additional, Cherchi, Roberto, additional, Dell’Amore, Andrea, additional, Della Beffa, Vittorio, additional, Dolci, Giampiero, additional, Droghetti, Andrea, additional, Ferrari, Paolo A., additional, Fontana, Diego, additional, Gargiulo, Gaetano, additional, Gasparri, Roberto, additional, Gavezzoli, Diego, additional, Ghisalberti, Marco, additional, Giovanardi, Michele, additional, Guerrera, Francesco, additional, Imperatori, Andrea, additional, Infante, Maurizio, additional, Iurilli, Luciano, additional, Lausi, Paolo, additional, Lo Giudice, Fabio, additional, Londero, Francesco, additional, Luzzi, Luca, additional, Lopez, Camillo, additional, Mancuso, Maurizio, additional, Maniscalco, Pio, additional, Margaritora, Stefano, additional, Meacci, Elisa, additional, Melloni, Giulio, additional, Morelli, Angelo, additional, Mucilli, Felice, additional, Natali, Pamela, additional, Negri, Giampiero, additional, Nicotra, Samuele, additional, Nosotti, Mario, additional, Pariscenti, Gianluca, additional, Perkmann, Reinhold, additional, Pernazza, Fausto, additional, Pirondini, Emanuele, additional, Poggi, Camilla, additional, Puma, Francesco, additional, Refai, Majed, additional, Rinaldo, Alessandro, additional, Rizzardi, Giovanna, additional, Rosso, Lorenzo, additional, Rotolo, Nicola, additional, Russo, Emanuele, additional, Sabbatini, Armando, additional, Scarci, Marco, additional, Spaggiari, Lorenzo, additional, Stefani, Alessandro, additional, Solli, Piergiorgio, additional, Surrente, Corrado, additional, Terzi, Alberto, additional, Torre, Massimo, additional, Vinci, Damiano, additional, Viti, Andrea, additional, Zaccagna, Gino, additional, and Zaraca, Francesco, additional

Published
2021
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25. Mechanical hepaticojejunostomy: can we use a circular stapler as a viable and safe alternative? -a retrospective study of a single center

Author

Nicolò Fabbri, Cavallesco Giorgio, Francesco Bagolini, Silvia Ferro, Paolo Carcoforo, Luigi Romeo, and Giancarlo Pansini

Subjects
medicine.medical_specialty, hepaticojejunostomy, 030230 surgery, Dehiscence, Anastomosis, jaundice, NO, 03 medical and health sciences, 0302 clinical medicine, biliodigestive anastomosis, Melena, medicine, LS7_4, pancreatoduodenectomy, Common bile duct, Wound dehiscence, business.industry, Biliary fistula, Retrospective cohort study, Jaundice, medicine.disease, hepaticojejunostomy, biliodigestive anastomosis, mechanical stapler, pancreatoduodenectomy, jaundice, mechanical stapler, Surgery, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Original Article, medicine.symptom, business
Abstract

Background Since the first years of the 1980s, some authors described the use of mechanical stapler for the creation of anastomosis in biliary surgery. However, the use of these devices has not spread during the following decades, and nowadays most centers usually craft hand-sewn anastomosis. Methods We retrospectively collected data from medical records, surgical registries and computerized databases about the use of mechanical circular staplers for the creation of hepaticojejunostomy at our institution. Results From 2012 to 2020, 11 stapled hepaticojejunostomy for both neoplastic and non-neoplastic diseases were performed at our institution. The mean age of the patient was 74, with a sex distribution of 5 men and 6 women. The mean preoperative common bile duct diameter was 19 mm. Preoperative blood samples showed mean total bilirubin of 6.95 mg/dL. No intraoperative complications were reported. Two patients (18%) had minor postoperative complications (1 wound dehiscence and 1 episode of melena that required blood transfusions), while no major complications occurred. No patients developed biliary fistula or anastomotic dehiscence. No one dies within 30 days from surgery. The mean postoperative length of stay was 13 days. Conclusions According to our limited experience, stapled hepaticojejunostomy seems to be a safe and effective technique in selected patients.

Published
2020

26. Treatment of fistula-in-ano: Outcome comparison between traditional surgery and novel approaches. A retrospective cohort study in a single center

Author

D&#039, FABBRİ, Nicolò, ASCANELLİ, Simona, RESTA, Giuseppe, CAVALLESCO, Giorgio, and CARCOFORO, Paolo

Subjects
Anal fistula,Fistulotomy,Fistulectomy,Seton,VAAFT,Lipogems®,Micro-fragmented adipose tissue, Anal fistül,Fistülotomi,Fistülektomi,Seton,VAAFT,Lipogems®,Mikro parçalanmış adipoz doku, Surgery, Cerrahi
Abstract

Amaç: Anal fistül iyi tanımlanmış bir hastalıktır ancak kesin bir cerrahi teknik geliştirilmemiştir. Hastanemizde 2012-2018 yılları arasında perianal fistül nedeniyle cerrahi tedavi uygulanan hastaları değerlendirmek için tek merkezli, retrospektif bir kohort çalışması yürüttük. Çalışmanın amacı, farklı cerrahi tekniklerin (Fistülotomi / fistülektomi ve seton, Video Destekli Anal Fistül Tedavisi (VAAFT), Mikro-parçalanmış yağ dokusu enjeksiyonu, Lipogems®) sonuçlarını karşılaştırmaktı.Yöntemler: Elektif cerrahi için uygun olan anal fistüllü 103 hastadan oluşan bir kohort, 2012 ve 2018 yılları arasında Ferrara'daki Sant’Anna Hastanesi’nde opere edildi. Tüm hastalara fistül traktını ve iç açıklığı belirlemek için ameliyat öncesi rektal tuşe ve manyetik rezonans görüntüleme (MRI) uygulandı. Hastalar, geçirdikleri her ameliyat için birer tane olmak üzere 4 gruba ayrıldı: Fistülotomi / fistülektomi ve seton, Video Destekli Anal Fistül Tedavisi (VAAFT), Mikro parçalı yağ dokusu enjeksiyonu, Lipogems®). Ameliyattan bir hafta sonra öznel ağrıyı değerlendirmek için sayısal derecelendirme ölçeği (NRS) kullanıldı ve sonuçlar kaydedildi. Puanlar, 0, hiç ağrı yok, ile 10, karşılaşılan en şiddetli ağrı, arasında değişmekteydi. Birincil sonlanım noktası, 1 yıllık takipte fistül rekürrensiydi. İkincil sonlanım noktası, ameliyat sonrası ağrının değerlendirilmesiydi.Bulgular: Ortanca yaşı 50 olan (aralık 21-89 yaş) 71 erkek ve 32 kadın çalışmaya dahil edildi. Bunlardan 79 hastaya yeni teşhis konulmuş, diğer 24 hasta daha önce ameliyat olmuş ve nüksetmişti. Anal fistül için toplam 118 cerrahi operasyon yapıldı. Takip süresince VAAFT sonrası 13 hastada, Mikro parçalı yağ dokusu enjeksiyonu sonrası 3 hastada, fistülotomi sonrası 4 hastada, fistülotomi sonrası 12 hastada, seton yerleştirme sonrasında 10 hastada ve Lipogems® tekniğinden sonra 8 hastada anal fistül rekürrensi gözlendi. Ameliyattan bir hafta sonra ağrı tüm hastalar tarafından 0 ile 10 arasında bir ölçekte değerlendirildi. VAAFT, mikro parçalı yağ dokusu enjeksiyonu, fistülotomi, fistülektomi, seton yerleştirme ve Lipogems® tekniği uygulanan hastaların ortalama skorları sırasıyla 1 (0- 5), 1.5 (0-8), 5 (3-8), 6.8 (5-9), 4.2 (2-6) ve 0’dı (0-2).Sonuç: Bu çalışma anal fistül yönetimindeki zorlukları ve çeşitli cerrahi seçenekleri sunmaktadır. VAAFT ve Mikro-parçalanmış yağ dokusu enjeksiyonu, anal fistül yönetiminde güvenli ve uygulanabilir seçenekler gibi görünmektedir ve kısa süreli iyileşme oranları, kontinans üzerinde kalıcı bir etki olmaksızın kabul edilebilirdir. Bununla birlikte, uzun vadeli sonuçları olan güvenilir veri yetersizliği olduğundan, bu teknikler, bu nedenle memnuniyetle karşılanmaktadır. Lipogems ® tekniği güvenli ve tekrarlanabilir bir işlemdir, ancak ne yazık ki deneyimlerimize göre, tekrarlayan sfinkterik anal fistülü olan hastalarda fistül iyileşmesini desteklememektedir. Bu tekniğin birinci basamak tedavi olarak kullanılmasını önermiyoruz., Aim: Fistula-in-ano is a well described disease but no definitive surgical technique has been developed. We conducted a retrospective cohort study in a single center to evaluate patients who underwent surgical treatment of a perianal fistula from 2012 to 2018 in our hospital. The aim of the study was to compare the outcome of different surgical techniques (Fistulotomy/fistulectomy and seton, Video-Assisted Anal Fistula Treatment (VAAFT), Micro-fragmented adipose tissue injection, Lipogems®).Methods: A cohort of 103 patients with anal fistula who qualified for elective surgery between 2012 and 2018 were recruited at Sant’Anna Hospital in Ferrara. All patients underwent a digital rectal examination and preoperative magnetic resonance imaging (MRI) to identify the fistula tract and internal opening. Patients were divided into 4 groups, one for each type of surgery they underwent: Fistulotomy/fistulectomy and seton, Video-Assisted Anal Fistula Treatment (VAAFT), Micro-fragmented adipose tissue injection, Lipogems®). Numerical rating scale (NRS) was used to assess subjective pain one week after surgery and documented. The scale ranged from 0 to 10, where 0 stands for no pain and 10 stands for worst pain ever faced. Primary end point was fistula recurrence at 1 year of follow-up. Secondary end point was evaluation of post-operative pain. Results: There were 71 males and 32 females, with a median age of 50 years (range 21-89 years). Among them, 79 patients were newly diagnosed, the other 24 patients had undergone previous surgery and had recurrence. In total, 118 surgical operation were performed for anal fistula. During the follow-up period, anal fistula recurrence was observed in 13 patients after VAAFT, 3 patients after Micro-fragmented adipose tissue injection, 4 after fistulotomy, 12 after fistulectomy, 10 after seton placement and 8 after Lipogems® technique. One week after surgery, pain was evaluated by all patients on a scale from 0 to 10. The mean scores of patients who underwent VAAFT, micro-fragmented adipose tissue injection, fistulotomy, fistulectomy, seton placement and Lipogems® technique were 1 (0-5), 1.5 (0-8), 5 (3-8), 6.8 (5-9), 4.2 (2-6) and 0 (0-2), respectively. Conclusion: This study presents the difficulties in managing anal fistulas and the variety of surgical options. VAAFT and Micro-fragmented adipose tissue injection appear to be safe and feasible options in the management of anal fistula, and short-term healing rates are acceptable with no sustained effect on continence. There is, however, a paucity of robust data with long-term outcomes. These techniques are thus welcome additions. Lipogems ® technique is a safe and reproducible procedure, unfortunately according to our experience, it does not promote fistula healing in patients with recurrent inter-sphincteric anal fistula. We do not suggest the use of this technique as a first-line treatment.

Published
2020

27. Video-assisted thoracoscopic lobectomy after neoadjuvant chemotherapy for non-small cell lung cancer: a multicenter propensity-matched study

Author

Dell’Amore, Andrea, primary, Lomangino, Ivan, additional, Tamburini, Nicola, additional, Bongiolatti, Stefano, additional, Parri, Nicola Sergio Forti, additional, Grossi, William, additional, Catelli, Chiara, additional, Lorenzoni, Giulia, additional, Gregori, Dario, additional, Nicotra, Samuele, additional, Zuin, Andrea, additional, Morelli, Angelo, additional, Solli, Piergiorgio, additional, Voltolini, Luca, additional, Cavallesco, Giorgio, additional, and Rea, Federico, additional

Published
2021
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29. Metformin Induces Apoptosis and Inhibits Notch1 in Malignant Pleural Mesothelioma Cells

Author

Rossini, Marika, primary, Martini, Fernanda, additional, Torreggiani, Elena, additional, Fortini, Francesca, additional, Aquila, Giorgio, additional, Sega, Francesco Vieceli Dalla, additional, Patergnani, Simone, additional, Pinton, Paolo, additional, Maniscalco, Pio, additional, Cavallesco, Giorgio, additional, Rizzo, Paola, additional, and Tognon, Mauro, additional

Published
2021
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31. Physiological effects of two driving pressure-based methods to set positive end-expiratory pressure during one lung ventilation

Author

Spadaro, Savino, primary, Grasso, Salvatore, additional, Karbing, Dan Stieper, additional, Santoro, Giuseppe, additional, Cavallesco, Giorgio, additional, Maniscalco, Pio, additional, Murgolo, Francesca, additional, Di Mussi, Rosa, additional, Ragazzi, Riccardo, additional, Rees, Stephen Edward, additional, Volta, Carlo Alberto, additional, and Fogagnolo, Alberto, additional

Published
2020
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35. Safety of lymphadenectomy during video-assisted thoracic surgery lobectomy. Analysis from a national database

Author

Gonfiotti, Alessandro, Bertani, Alessandro, Nosotti, Mario, Viggiano, Domenico, Bongiolatti, Stefano, Bertolaccini, Luca, Droghetti, Andrea, Solli, Piergiorgio, Crisci, Roberto, Voltolini, Luca, Curcio, Carlo, Amore, Dario, Marulli, Giuseppe, Nicotra, Samuele, De Negri, Andrea, Maineri, Paola, Di Rienzo, Gaetano, Lopez, Camillo, Divisi, Duilio, Morelli, Angelo, Russo, Emanuele, Londero, Francesco, Rosso, Lorenzo, Spaggiari, Lorenzo, Gasparri, Roberto, Baietto, Guido, Casadio, Caterina, Infante, Maurizio, Benato, Cristiano, Alloisio, Marco, Bottoni, Edoardo, Giovanardi, Andrea, Cardillo, Giuseppe, Carleo, Francesco, Stella, Franco, Dolci, Giampiero, Puma, Francesco, Vinci, Damiano, Cavallesco, Giorgio, Maniscalco, Pio, Argnani, Desideria, Ampollini, Luca, Carbognani, Paolo, Terzi, Alberto, Viti, Andrea, Negri, Giampiero, Bandiera, Alessandro, Perkmann, Reinhold, Zaraca, Francesco, Ibrahim, Mohsen, Poggi, Camilla, Mucilli, Felice, Camplese, Pierpaolo, Luzzi, Luca, Ghisalberti, Marco, Imperatori, Andrea, Rotolo, Nicola, Bortolotti, Luigi, Rizzardi, Giovanna, Torre, Massimo, Rinaldo, Alessandro, Sabbatini, Armando, Refai, Majed, Benvenuti, Mauro Roberto, Benetti, Diego, Stefani, Alessandro, Natali, Pamela, Lausi, Paolo, Guerrera, Francesco, Gonfiotti, Alessandro, Bertani, Alessandro, Nosotti, Mario, Viggiano, Domenico, Bongiolatti, Stefano, Bertolaccini, Luca, Droghetti, Andrea, Solli, Piergiorgio, Crisci, Roberto, Voltolini, Luca, Curcio, Carlo, Amore, Dario, Marulli, Giuseppe, Nicotra, Samuele, De Negri, Andrea, Maineri, Paola, Di Rienzo, Gaetano, Lopez, Camillo, Divisi, Duilio, Morelli, Angelo, Russo, Emanuele, Londero, Francesco, Rosso, Lorenzo, Spaggiari, Lorenzo, Gasparri, Roberto, Baietto, Guido, Casadio, Caterina, Infante, Maurizio, Benato, Cristiano, Alloisio, Marco, Bottoni, Edoardo, Giovanardi, Andrea, Cardillo, Giuseppe, Carleo, Francesco, Stella, Franco, Dolci, Giampiero, Puma, Francesco, Vinci, Damiano, Cavallesco, Giorgio, Maniscalco, Pio, Argnani, Desideria, Ampollini, Luca, Carbognani, Paolo, Terzi, Alberto, Viti, Andrea, Negri, Giampiero, Bandiera, Alessandro, Perkmann, Reinhold, Zaraca, Francesco, Ibrahim, Mohsen, Poggi, Camilla, Mucilli, Felice, Camplese, Pierpaolo, Luzzi, Luca, Ghisalberti, Marco, Imperatori, Andrea, Rotolo, Nicola, Bortolotti, Luigi, Rizzardi, Giovanna, Torre, Massimo, Rinaldo, Alessandro, Sabbatini, Armando, Refai, Majed, Benvenuti, Mauro Roberto, Benetti, Diego, Stefani, Alessandro, Natali, Pamela, Lausi, Paolo, and Guerrera, Francesco

Subjects
Male, Lung Neoplasms, Time Factors, medicine.medical_treatment, 030204 cardiovascular system & hematology, Logistic regression, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, 80 and over, Prospective Studies, Lobectomy, Lung cancer, Video-assisted thoracic surgery, Adult, Aged, Aged, 80 and over, Female, Follow-Up Studies, Humans, Lymph Node Excision, Lymphatic Metastasis, Mediastinum, Middle Aged, Neoplasm Staging, Pneumonectomy, Thoracic Surgery, Video-Assisted, Treatment Outcome, Prospective cohort study, Non-Small-Cell Lung, Thoracic Surgery, General Medicine, medicine.anatomical_structure, Cardiothoracic surgery, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Video-Assisted, NO, 03 medical and health sciences, medicine, Rank correlation, business.industry, Carcinoma, medicine.disease, Surgery, 030228 respiratory system, Lymphadenectomy, business, Lobectomy, Lung cancer, Video-assisted thoracic surgery
Abstract

OBJECTIVES The Italian VATS Group database was accessed to evaluate whether preoperative and intraoperative factors may affect the safety of lymphadenectomy (LA) during video-assisted thoracic surgery lobectomy. METHODS All video-assisted thoracic surgery lobectomy procedures performed between 1 January 2014 and 30 March 2017 for non-small-cell lung cancer with cN0 or cN1 disease were identified in the database. LA safety was evaluated based on intraoperative (operative time, bleeding and conversion rate) and postoperative (30-day morbidity and mortality, chest drain duration and length of stay) outcomes and was correlated with the number of resected lymph nodes and the rates of nodal upstaging. Continuous variables were presented as mean ± standard deviation and compared using the unpaired t-test; the X2 test was used for categorical variables. Univariable analysis was performed on selected variables. Significant variables (P < 0.30) were entered into a Cox multivariable logistic regression model, using the overall and specific occurrence of complications as dependent variables. The Spearman's rank correlation coefficient was applied as needed. RESULTS A total of 3181 cases (2077 men, 65.3%; mean age of 69 years) met the enrolment criteria. Final pathology was consistent with adenocarcinoma (n = 2262, 67.5%), squamous cell (n = 520, 15.5%), typical (n = 184, 5.5%) and atypical carcinoid (n = 48, 1.4%) and other (n = 335, 10%). The mean number of resected lymph nodes was 13.42 ± 8.24; nodal upstaging occurred in 308 of 3181 (9.68%) cases. Six hundred and fifty-five complications were recorded in 404 (12.7%) patients; in this series, no mortality was observed. Univariable and multivariable analyses did not show any association between the extension of LA and intraoperative or postoperative outcomes. The number of resected lymph nodes and nodal upstagings showed a minimal correlation with intraoperative outcomes and a moderate correlation with postoperative air leak (p = 0.35 and p = 0.48, respectively), arrhythmia (p = 0.29 and p = 0.35, respectively), chest drain duration (p = 0.35 and p = 0.51, respectively) and length of stay (p = 0.35). CONCLUSIONS Based on the VATS Group data, video-assisted thoracic surgery LA proved to be safe and displayed good outcomes even when performed with an extended approach.

Published
2018

37. Video-assisted thoracoscopic lobectomy after neoadjuvant chemotherapy for non-small cell lung cancer: a multicenter propensity-matched study.

Author

Dell'Amore, Andrea, Lomangino, Ivan, Tamburini, Nicola, Bongiolatti, Stefano, Parri, Nicola Sergio Forti, Grossi, William, Catelli, Chiara, Lorenzoni, Giulia, Gregori, Dario, Nicotra, Samuele, Zuin, Andrea, Morelli, Angelo, Solli, Piergiorgio, Voltolini, Luca, Cavallesco, Giorgio, and Rea, Federico

Subjects
NON-small-cell lung carcinoma, PROGRESSION-free survival, PROPENSITY score matching, NEOADJUVANT chemotherapy, VIDEO-assisted thoracic surgery, VIDEOS, LOBECTOMY (Lung surgery), SURGICAL complications
Abstract

Background: The role of video-assisted thoracoscopic surgery for the treatment of non-small-cell lung cancer after neoadjuvant chemotherapy remains controversial. The aim of this study is to demonstrate the reliability of video-assisted lobectomy compared to the open approach by evaluating perioperative and long-term outcomes. Methods: In this retrospective, multicentric study from January 2010 to December 2018, we included all patients with non-small-cell lung cancer who underwent lobectomy through the video-assisted or open approach after neoadjuvant chemotherapy. The perioperative outcomes, including data concerning the feasibility of the surgical procedure, the occurrence of any medical and surgical complications and long-term oncological evidence, were collected and compared between the two groups. To minimize selection bias, propensity score matching was performed. Results: A total of 286 patients were enrolled: 193 underwent thoracotomy lobectomy, and 93 underwent VATS lobectomy. The statistical analysis showed that surgical time (P < 0.001), drainage time (P < 0.001), days of hospitalization (P < 0.001) and VAS at discharge (P = 0.042) were lower in the VATS group. The overall survival and disease-free survival were equivalent for the two techniques on long-term follow-up. Conclusions: VATS lobectomy represents a valid therapeutic option in patients affected by non-small-cell lung cancer after neoadjuvant chemotherapy. The VATS approach in our experience seems to be superior in terms of the perioperative outcomes, while maintaining oncological efficacy. [ABSTRACT FROM AUTHOR]

Published
2022
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38. Extracorporeal versus intracorporeal anastomosis in laparoscopic right hemicolectomy for cancer.

Author

Anania, Gabriele, Tamburini, Nicola, Sanzi, Marcello, Schimera, Antonio, Bombardini, Cristina, Resta, Giuseppe, Marino, Serafino, Valpiani, Giorgia, Valentini, Alessandra, and Cavallesco, Giorgio

Subjects
COLON tumors, SURGICAL anastomosis, COLECTOMY, LAPAROSCOPIC surgery, RETROSPECTIVE studies, CANCER patients
Abstract

This study aimed at assessing the long-term oncological outcomes of intracorporeal ileocolic anastomosis (ICA) for laparoscopic right hemicolectomy for colon cancer compared with extracorporeal anastomosis (ECA). We performed a retrospective analysis of 149 consecutive patients who underwent laparoscopic right hemicolectomy for colon cancer between January 2006 and December 2012. Eighty and 69 patients underwent intracorporeal and ECA, respectively. The two groups were demographically comparable. ICA exhibited a significantly shorter operative time (p <.0001), while local relapse and length of hospital stay did not significantly differ among the groups (p =.724 and.310, respectively). There was no significant difference in median number of retrieved lymph node. The overall survival and the disease-free survival at five years did not significantly differ among the groups. Intracorporeal ICA can reduce operative time and is associated with similar postoperative and long-term oncological outcomes compared to the ECA technique. [ABSTRACT FROM AUTHOR]

Published
2022
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40. Nodal management and upstaging of disease: Initial results from the Italian VATS Lobectomy Registry

Author

Bertani, Alessandro, Gonfiotti, Alessandro, Nosotti, Mario, Ferrari, Paolo Albino, De Monte, Lavinia, Russo, Emanuele, Di Paola, Gioacchino, Solli, Piero, Droghetti, Andrea, Bertolaccini, Luca, Crisci, Roberto, Curcio, Carlo, Amore, Dario, Marulli, Giuseppe, Nicotra, Samuele, De Negri, Andrea, Maineri, Paola, di Rienzo, Gaetano, Lopez, Camillo, Morelli, Angelo, Londero, Francesco, Spaggiari, Lorenzo, Gasparri, Roberto, Baietto, Guido, Casadio, Caterina, Infante, Maurizio, Benato, Cristiano, Alloisio, Marco, Bottoni, Edoardo, Cardillo, Giuseppe, Carleo, Francesco, Stella, Franco, Dolci, Giampiero, Puma, Francesco, Vinci, Damiano, Cavallesco, Giorgio, Maniscalco, Pio, Ampollini, Luca, Carbognani, Paolo, Terzi, Alberto, Viti, Andrea, Negri, Giampiero, Bandiera, Alessandro, Perkmann, Reinhold, Zaraca, Francesco, Andretti, Claudio, Poggi, Camilla, Mucilli, Felice, Camplese, Pierpaolo, Luzzi, Luca, Ghisalberti, Marco, Imperatori, Andrea, Rotolo, Nicola, Bortolotti, Luigi, Rizzardi, Giovanna, Torre, Massimo, Rinaldo, Alessandro, Sabbatini, Armando, Refai, Majed, Benvenuti, Mauro Roberto, Benetti, Diego, Stefani, Alessandro, Natali, Pamela, Lausi, Paolo, Guerrera, Francesco, Bertani, A, Gonfiotti, A, Nosotti, M, Ferrari, Pa, De Monte, L, Russo, E, Di Paola, G, Solli, P, Droghetti, A, Bertolaccini, L, Crisci, R, Italian VATS, Group, Negri, G, Bertani, Alessandro, Gonfiotti, Alessandro, Nosotti, Mario, Ferrari, Paolo Albino, De Monte, Lavinia, Russo, Emanuele, Di Paola, Gioacchino, Solli, Piero, Droghetti, Andrea, Bertolaccini, Luca, Crisci, Roberto, Curcio, Carlo, Amore, Dario, Marulli, Giuseppe, Nicotra, Samuele, De Negri, Andrea, Maineri, Paola, di Rienzo, Gaetano, Lopez, Camillo, Morelli, Angelo, Londero, Francesco, Spaggiari, Lorenzo, Gasparri, Roberto, Baietto, Guido, Casadio, Caterina, Infante, Maurizio, Benato, Cristiano, Alloisio, Marco, Bottoni, Edoardo, Cardillo, Giuseppe, Carleo, Francesco, Stella, Franco, Dolci, Giampiero, Puma, Francesco, Vinci, Damiano, Cavallesco, Giorgio, Maniscalco, Pio, Ampollini, Luca, Carbognani, Paolo, Terzi, Alberto, Viti, Andrea, Negri, Giampiero, Bandiera, Alessandro, Perkmann, Reinhold, Zaraca, Francesco, Andretti, Claudio, Poggi, Camilla, Mucilli, Felice, Camplese, Pierpaolo, Luzzi, Luca, Ghisalberti, Marco, Imperatori, Andrea, Rotolo, Nicola, Bortolotti, Luigi, Rizzardi, Giovanna, Torre, Massimo, Rinaldo, Alessandro, Sabbatini, Armando, Refai, Majed, Benvenuti, Mauro Roberto, Benetti, Diego, Stefani, Alessandro, Natali, Pamela, Lausi, Paolo, and Guerrera, Francesco

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lymph node (LN), VATS lobectomy, Nodal upstaging, 030204 cardiovascular system & hematology, Resection, NO, 03 medical and health sciences, 0302 clinical medicine, medicine, Quantitative assessment, Lymph node, Surgical approach, Receiver operating characteristic, business.industry, lymph node (LN), nodal upstaging, Surgery, Dissection, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Original Article, Radiology, business
Abstract

Background: VATS lobectomy is an established option for the treatment of early-stage NSCLC. Complete lymph node dissection (CD), systematic sampling (SS) or resecting a specific number of lymph nodes (LNs) and stations are possible intra-operative LN management strategies. Methods: All VATS lobectomies from the “Italian VATS Group” prospective database were retrospectively reviewed. The type of surgical approach (CD or SS), number of LN resected (RN), the positive/resected LN ratio (LNR) and the number and types of positive LN stations were recorded. The rates of nodal upstaging were assessed based on different LN management strategies. Results: CD was the most frequent approach (72.3%). Nodal upstaging rates were 6.03% (N0-to-N1), 5.45% (N0-to-N2), and 0.58% (N1-to-N2). There was no difference in N1 or N2 upstaging rates between CD and SS. The number of resected nodes was correlated with both N1 (OR =1.02; CI, 1.01–1.04; P=0.03) and N2 (OR =1.02; CI, 1.01–1.05; P=0.001) upstaging. Resecting 12 nodes had the best ability to predict upstaging (6 N1 LN or 7 N2 LN). The finding of two positive LN stations best predicted N2 upstaging [area under the curve (AUC) of receiver operating characteristic (ROC) =0.98]. Conclusions: Nodal upstaging (and, indirectly, the effectiveness of intra-operative nodal management) cannot be predicted based on the surgical technique (CD or SS). A quantitative assessment of intra-operative LN management may be a more appropriate and measurable approach to justify the extension of LN resection during VATS lobectomy.

Published
2017

45. Technical results, clinical efficacy and predictors of outcome of intercostal arteries embolization for hemothorax: a two-institutions’ experience

Author

Tamburini, Nicola, primary, Carriel, Nicole, additional, Cavallesco, Giorgio, additional, Molins, Laureano, additional, Galeotti, Roberto, additional, Guzmán, Rudith, additional, Salviato, Elisabetta, additional, Sánchez-Lorente, David, additional, Maietti, Elisa, additional, Maniscalco, Pio, additional, and Boada, Marc, additional

Published
2019
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46. Chest wall reconstruction using a new titanium mesh: a multicenters experience

Author

Tamburini, Nicola, primary, Grossi, William, additional, Sanna, Stefano, additional, Campisi, Alessio, additional, Londero, Francesco, additional, Maniscalco, Pio, additional, Dolci, Giampiero, additional, Quarantotto, Francesco, additional, Daddi, Niccolò, additional, Morelli, Angelo, additional, Cavallesco, Giorgio, additional, and Dell’Amore, Andrea, additional

Published
2019
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47. Conversion due to vascular injury during video-assisted thoracic surgery lobectomy: A multicentre retrospective analysis from the Italian video-assisted thoracic surgery group registry

Author

Bertolaccini, Luca, primary, Davoli, Fabio, additional, Pardolesi, Alessandro, additional, Brandolini, Jury, additional, Argnani, Desideria, additional, Bertani, Alessandro, additional, Droghetti, Andrea, additional, Gonfiotti, Alessandro, additional, Divisi, Duilio, additional, Crisci, Roberto, additional, Solli, Piergiorgio, additional, Bertolaccini, Luca, additional, Nosotti, Mario, additional, Curcio, Carlo, additional, Amore, Dario, additional, Marulli, Giuseppe, additional, Nicotra, Samuele, additional, De Negri, Andrea, additional, Maineri, Paola, additional, di Rienzo, Gaetano, additional, Lopez, Camillo, additional, Morelli, Angelo, additional, Londero, Francesco, additional, Spaggiari, Lorenzo, additional, Gasparri, Roberto, additional, Baietto, Guido, additional, Casadio, Caterina, additional, Infante, Maurizio, additional, Benato, Cristiano, additional, Alloisio, Marco, additional, Bottoni, Edoardo, additional, Cardillo, Giuseppe, additional, Carleo, Francesco, additional, Stella, Franco, additional, Dolci, Giampiero, additional, Puma, Francesco, additional, Vinci, Damiano, additional, Cavallesco, Giorgio, additional, Maniscalco, Pio, additional, Ampollini, Luca, additional, Carbognani, Paolo, additional, Terzi, Alberto, additional, Viti, Andrea, additional, Negri, Giampiero, additional, Bandiera, Alessandro, additional, Perkmann, Reinhold, additional, Zaraca, Francesco, additional, Andretti, Claudio, additional, Poggi, Camilla, additional, Mucilli, Felice, additional, Camplese, Pierpaolo, additional, Luzzi, Luca, additional, Ghisalberti, Marco, additional, Imperatori, Andrea, additional, Rotolo, Nicola, additional, Bortolotti, Luigi, additional, Rizzardi, Giovanna, additional, Torre, Massimo, additional, Rinaldo, Alessandro, additional, Sabbatini, Armando, additional, Refai, Majed, additional, Benvenuti, Mauro Roberto, additional, Benetti, Diego, additional, Stefani, Alessandro, additional, Natali, Pamela, additional, Lausi, Paolo, additional, and Guerrera, Francesco, additional

Published
2019
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50. Erratum: Nodal management and upstaging of disease: Initial results from the Italian VATS Lobectomy Registry [J Thorac Dis, 9, (2017), (2061-2070)] DOI: 10.21037/jtd.2017.06.12

Author

Bertani, Alessandro, Gonfiotti, Alessandro, Nosotti, Mario, Ferrari, Paolo Albino, De Monte, Lavinia, Russo, Emanuele, Di Paola, Gioacchino, Solli, Piero, Droghetti, Andrea, Bertolaccini, Luca, Crisci, Roberto, Curcio, Carlo, Amore, Dario, Marulli, Giuseppe, Nicotra, Samuele, De Negri, Andrea, Maineri, Paola, di Rienzo, Gaetano, Lopez, Camillo, Morelli, Angelo, Londero, Francesco, Spaggiari, Lorenzo, Gasparri, Roberto, Baietto, Guido, Casadio, Caterina, Infante, Maurizio, Benato, Cristiano, Alloisio, Marco, Bottoni, Edoardo, Cardillo, Giuseppe, Carleo, Francesco, Stella, Franco, Dolci, Giampiero, Puma, Francesco, Vinci, Damiano, Cavallesco, Giorgio, Maniscalco, Pio, Ampollini, Luca, Carbognani, Paolo, Terzi, Alberto, Viti, Andrea, Negri, Giampiero, Bandiera, Alessandro, Perkmann, Reinhold, Zaraca, Francesco, Andretti, Claudio, Poggi, Camilla, Mucilli, Felice, Camplese, Pierpaolo, Luzzi, Luca, Ghisalberti, Marco, Imperatori, Andrea, Rotolo, Nicola, Bortolotti, Luigi, Rizzardi, Giovanna, Torre, Massimo, Rinaldo, Alessandro, Sabbatini, Armando, Refai, Majed, Benvenuti, Mauro Roberto, Benetti, Diego, Stefani, Alessandro, Natali, Pamela, Lausi, Paolo, and Guerrera, Francesco

Subjects
Pulmonary and Respiratory Medicine, NO
Published
2017

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