1. Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation.
- Author
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Lee, Po-Yen, Chang, Yo-Chen, Liu, Pei-Kang, Kao, Tzu-En, Wu, Horng-Jiun, Chen, Kuo-Jen, Wu, Kwou-Yeung, Cheng, Kai-Chun, and Wu, Wen-Chuan
- Subjects
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RETINA transplants , *HEALTH outcome assessment , *RETROSPECTIVE studies , *ACQUISITION of data , *TREATMENT effectiveness , *MEDICAL records , *OPTICAL coherence tomography , *VISUAL acuity , *DESCRIPTIVE statistics , *RETINAL diseases , *DATA analysis software , *OPHTHALMIC surgery , *MEDICAL needs assessment - Abstract
Purpose. To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). Design. Retrospective interventional case series. Methods. We reviewed 9 patients who underwent ART for their refractory large MH. In this extended follow-up study, postoperative assessment including spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA) were recorded at 12, 15, 18, 21, and 24 months after surgery. Results. The macular hole of all patients appeared successfully closed during the whole follow-up period. The mean logMAR BCVA improved from 1.61 ± 0.44 (preoperative) to 0.72 ± 0.30 (12 months after surgery) (p < 0.001). Thereafter, the mean BCVA remained stable at each follow-up. At the mean 16.0 ± 0.8 months postoperatively, inner retinal cystic changes were observed in 4 eyes (44.4%), but these did not significantly affect vision. Conclusion. ART is a good alternative technique for closing large refractory macular holes. Although inner retinal cystic changes were observed in 4 eyes (44.4%), this phenomenon did not significantly affect visual acuity. It provides long-term good anatomical and functional results, especially in cases where insufficient ILM or lens capsule are left. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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