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Polycystic ovary syndrome (PCOS),a common clinical endocrine disorder, is the main cause of anovulatory infertility in women of childbearing age. Due to the particular endocrine disorders in PCOS patients, it is hard to predict ovarian responses to drugs during controlled ovarian stimulation (COS). So, poor ovarian responses and ovarian hyperstimulation syndrome (OHSS) are incredibly common. The common protocols used in IVF for PCOS patients include long protocol, antagonist protocol, mild stimulation protocol, revised super-long protocol, super-long protocol and in vitro maturation (IVM). Presently, long protocol is most frequently used in most of reproductive centers. At the same time, antagonist protocol and mild stimulation protocol, as new protocols, are gradually favored by many clinicians. Super-long protocol and the revised super-long protocol, as the improved traditional protocols, have also obtained good clinic results. IVM,as a technical innovation, can simplify treatment and reduce the risk of OHSS. During IVF for patients with PCOS,it is the key point for clinicians to choose the optimal and economical treatment, to get high -quality eggs and embryos, and to avoid complications such as OHSS. [ABSTRACT FROM AUTHOR]

Polycystic ovary syndrome(PCos), a common endocrinal disorder in women of reproductive age, causes the non-ovulation infertility. It is difficult to reach the consensus on the diagnostic criteria due to the high heterogeneity of clinical presentation and biochemical criterion in PCos patients. At present, the common international criteria include NIH criteria, Rotterdam criteria and AEs criteria. The expert consensus of China and the clinical practice guideline of AACE were also published. it is urgent to develop a diagnostic criterion of PCos based on Chinese features. The accurate pathogenesis of PCos is still unclear, which is related to genetic, environment, psychology, and/or combined factors. Based on characteristics of patients, therapy for those women with fertility requirement should be individual, including mainly the adjustment of life style, oral contraceptives, insulin sensitizing agents, ovulation treatment, assisted reproductive technology and operation. Meanwhile, the long -term management should be emphasized to avoid the long-term complications. In this article, the advance in diagnosis, pathogenesis and treatment of PCos was discussed. [ABSTRACT FROM AUTHOR]