181 results on '"Cheng, Yi-Qiang"'
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2. Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer
3. Type I Polyketide Synthase Requiring a Discrete Acyltransferase for Polyketide Biosynthesis
4. Developing new targeting strategy for androgen receptor variants in castration resistant prostate cancer
5. Hybrid Peptide-Polyketide Natural Products: Biosynthesis and Prospects Towards Engineering Novel Molecules
6. Identification and characterization of the spiruchostatin biosynthetic gene cluster enable yield improvement by overexpressing a transcriptional activator
7. Enzymology, Molecular Genetics, and Regulation of Biosynthesis of the Host-Selective Toxin HC-Toxin
8. Genome-guided discovery of diverse natural products from Burkholderia sp.
9. Determination of thailandepsin B in rat plasma with a LC–MS/MS method
10. Extractive fermentation for enhanced production of thailandepsin A from Burkholderia thailandensis E264 using polyaromatic adsorbent resin Diaion HP-20
11. Yersinia ironomics: comparison of iron transporters among Yersiniapestis biotypes and its nearest neighbor, Yersinia pseudotuberculosis
12. Structural determinants stabilizing the axial channel of ClpP for substrate translocation
13. The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis
14. Identification and localization of gene cluster enconding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140
15. Chapter 8 Type I Polyketide Synthases That Require Discrete Acyltransferases
16. Polyketide Biosynthesis beyond the Type I, II, and III Polyketide Synthase Paradigms: A Progress Report
17. A putative branched-chain-amino-acid transaminase gene required for HC-toxin biosynthesis and pathogenicity in Cochliobolous carbonum
18. Targeted mutants of Cochliobolus carbonum lacking the two major extracellular polygalacturonases
19. Enzymology, Molecular Genetics, and Regulation of Biosynthesis of the Host-Selective Toxin HC-Toxin
20. Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy
21. Origin and bioactivities of thiosulfinated FK228
22. Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228
23. Abstract A090: Targeting androgen receptor (AR) variants in castration-resistant prostate cancer (CRPC) with a cancer-specific theranostic agent
24. Engineer Novel Anticancer Bioagents
25. Genomics-Guided Discovery of Thailanstatins A, B, and C As Pre-mRNA Splicing Inhibitors and Antiproliferative Agents from Burkholderia thailandensisMSMB43
26. Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968
27. Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin
28. Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growthin vivo
29. Minimum Information about a Biosynthetic Gene cluster: commentary
30. Engineered Production of Tryprostatins in E. coli through Reconstitution of a Partial ftm Biosynthetic Gene Cluster from Aspergillus sp
31. HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork
32. Improved production of cytotoxic thailanstatins A and D through metabolic engineering of Burkholderia thailandensis MSMB43 and pilot scale fermentation
33. Target engagement and drug residence time can be observed in living cells with BRET
34. Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer
35. Thailandepsin A
36. Path Planning of Flying Robot for Overhead Powerline Inspection Based on Key Points Algorithm
37. The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth
38. Activation of ClpP Protease by ADEP Antibiotics: Insights from Hydrogen Exchange Mass Spectrometry
39. Molecular analysis of HC-toxin biosynthesis in Cochliobolus carbonum
40. Isolation and characterization of spliceostatin B, a new analogue of FR901464, from Pseudomonas sp. No. 2663
41. Effects of Thailanstatins on Glucocorticoid Response in Trabecular Meshwork and Steroid-Induced Glaucoma
42. Abstract 2257: Thailanstatins: New pre-mRNA splicing inhibitors and potent antiproliferative agents discovered from Burkholderia Thailandensis MSMB43.
43. Abstract 1014: Thailandepsin A, a new HDAC inhibitor, reduces cellular proliferation and activates the Notch pathway in human carcinoids cancer cells.
44. Genomics-Guided Discovery of Thailanstatins A, B, and C As Pre-mRNA Splicing Inhibitors and Antiproliferative Agents from Burkholderia thailandensis MSMB43
45. Cyclo(-L-prolyl-L-valinyl-) fromBurkholderia thailandensisMSMB43
46. FK228 fromBurkholderia thailandensisMSMB43
47. Abstract 4646: Toward engineering of novel anticancer bio-agents
48. Discovery and activity profiling of thailandepsins A through F, potent histone deacetylase inhibitors, from Burkholderia thailandensis E264
49. Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of ClpP Protease
50. Thailandepsins: Bacterial Products with Potent Histone Deacetylase Inhibitory Activities and Broad-Spectrum Antiproliferative Activities
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