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1. Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein

Author

Huang, Quilong ;, Yu, Liping, Petros, Andrew M., Gunasekara, Angelo, Liu, Zhihong, Xu, Nan, Hajduk, Philip, Mack, Jamey, Fesik, Stephen W., and Olejniczak, Edward T.

Subjects
Biochemistry -- Research, Coronavirus infections -- Structure, Coronavirus infections -- Research, Severe acute respiratory syndrome -- Structure, Severe acute respiratory syndrome -- Research, RNA -- Research, Biological sciences, Chemistry
Abstract

The three-dimensional structure of the N-terminal domain of the severe acute respiratory syndrome (SARS) coronavirus (CoV) nucleocapsid protein is presented. By using a nuclear magnetic resonance (NMR) spectroscopy, the low molecular weight compounds that bind to the RNA-binding face of the protein is discussed.

Published
2004

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