1. Primary Mucinous Cystadenocarcinoma of the Breast Intermixed with Pleomorphic Invasive Lobular Carcinoma: The First Report of This Rare Association.
- Author
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Vegni, Federica, D'Alessandris, Nicoletta, Santoro, Angela, Angelico, Giuseppe, Scaglione, Giulia, Carlino, Angela, Arciuolo, Damiano, Valente, Michele, Sfregola, Stefania, Natale, Maria, Sanchez, Alejandro Martin, Masciullo, Valeria, Zannoni, Gian Franco, and Mulè, Antonino
- Subjects
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BREAST , *LOBULAR carcinoma , *PROGESTERONE receptors , *ESTROGEN receptors , *MUCINOUS adenocarcinoma , *OVARIES - Abstract
Primary mucinous cystadenocarcinoma (MCA) is a rare breast carcinoma subtype showing overlapping histopathological features with mucinous cystadenocarcinoma of the ovary and pancreas. Current literature data suggest a favorable prognosis of breast MCAs despite its immunoprofile usually revealing lack of expression of estrogen receptor, progesterone receptor and HER-2 and high Ki67. As far as we know, only 36 cases have been reported in the literature to date. Its ambiguous morpho-phenotypic profile makes histological diagnosis very challenging. It must be distinguished from typical mucin-producing breast carcinomas and, above all, metastases from the same histotype in other sites (ovary, pancreas, appendix). Herein, we report the case of a primary breast MCA occurring in a 41-year-old female with peculiar histological features. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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