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1. Retraction Note: Increased Gut Redox and Depletion of Anaerobic and Methanogenic Prokaryotes in Severe Acute Malnutrition

Author

Million, Matthieu, Alou, Maryam Tidjani, Khelaifia, Saber, Bachar, Dipankar, Lagier, Jean-Christophe, Dione, Niokhor, Brah, Souleymane, Hugon, Perrine, Lombard, Vincent, Armougom, Fabrice, Fromonot, Julien, Robert, Catherine, Michelle, Caroline, Diallo, Aldiouma, Fabre, Alexandre, Guieu, Régis, Sokhna, Cheikh, Henrissat, Bernard, Parola, Philippe, and Raoult, Didier

Published
2023
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5. Using social contact data to improve the overall effect estimate of a cluster-randomized influenza vaccination program in Senegal

Author

Potter, Gail E., Carnegie, Nicole Bohme, Sugimoto, Jonathan D., Diallo, Aldiouma, Victor, John C., Neuzil, Kathleen, and Halloran, M. Elizabeth

Subjects
Statistics - Applications
Abstract

This study estimates the overall effect of two influenza vaccination programs consecutively administered in a cluster-randomized trial in western Senegal over the course of two influenza seasons from 2009-2011. We apply cutting-edge methodology combining social contact data with infection data to reduce bias in estimation arising from contamination between clusters. Our time-varying estimates reveal a reduction in seasonal influenza from the intervention and a nonsignificant increase in H1N1 pandemic influenza. We estimate an additive change in overall cumulative incidence (which was 6.13% in the control arm) of -0.68 percentage points during Year 1 of the study (95% CI: -2.53, 1.18). When H1N1 pandemic infections were excluded from analysis, the estimated change was -1.45 percentage points and was significant (95% CI, -2.81, -0.08). Because cross-cluster contamination was low (0-3% of contacts for most villages), an estimator assuming no contamination was only slightly attenuated (-0.65 percentage points). These findings are encouraging for studies carefully designed to minimize spillover. Further work is needed to estimate contamination, and its effect on estimation, in a variety of settings.

Published
2020

8. Investigating linkage to care following community‐based screening for hepatitis B virus in rural Senegal: A mixed methods study.

Author

Coste, Marion, Diouf, Assane, Ndong, Cilor, Diouf, Aissatou, Périères, Lauren, Nishimwe, Marie Libérée, Bureau, Morgane, Ndiaye, Assane, Maradan, Gwenaëlle, Diallo, Aldiouma, Boyer, Sylvie, Bérenger, Cyril, Bousmah, Marwan‐al‐Qays, Carrieri, Patrizia, de Sèze, Maëlle, Djaogol, Tchadine, Marcellin, Fabienne, Treibich, Carole, Ba, Elhadji, and Dièye, Fambaye

Subjects
CHRONIC hepatitis B, HEPATITIS B virus, AGRICULTURAL resources, CONTINUUM of care, MEDICAL centers
Abstract

This paper investigates linkage to care following community‐based screening for hepatitis B virus (HBV) in rural Senegal. HBV‐positive participants who completed a biological and clinical examination to assess liver disease and treatment eligibility were referred to a regional hospital (if eligible for treatment), invited to join the Sen‐B research cohort study (adults with detectable viral load) or referred to their local health centre (all others). Logistic regressions were conducted to investigate factors associated with (i) uptake of the scheduled post‐screening examination, and (ii) HBV management initiation. Obstacles to HBV management were identified using thematic analysis of in‐depth patient interviews. Of the 206 HBV‐positive participants, 163 (79.1%) underwent the examination; 47 of the 163 (28.8%) initiated HBV management. Women, people not migrating for >6 months/year, individuals living in households with more agricultural and monetary resources, with other HBV‐positive participants, and beneficiaries of the national cash transfer program, were all more likely to undergo the examination. The likelihood of joining the Sen‐B cohort increased with household monetary resources, but decreased with agricultural resources. Initiation of HBV management in local health centre was higher among participants with a non‐agricultural economic activity. Individuals reported wariness and confusion about HBV management content and rationale at various stages of the care continuum, in particular with respect to venous blood sampling and management without treatment. In conclusion, HBV community‐based test‐and‐treat strategies are feasible, but early loss to follow‐up must be addressed through simplified, affordable management and community support and sensitization. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Towards an Efficient Prediction Model of Malaria Cases in Senegal

Author

Mbaye, Ousseynou, Ba, Mouhamadou Lamine, Camara, Gaoussou, Sy, Alassane, Mboup, Balla Mbacké, Diallo, Aldiouma, Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin (Sherman), Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Bassioni, Ghada, editor, Kebe, Cheikh M.F., editor, Gueye, Assane, editor, and Ndiaye, Ababacar, editor

Published
2019
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16. Household transmission of Neisseria meningitidis in the African meningitis belt: a longitudinal cohort study

Author

Ali, Oumer, Aseffa, Abraham, Omer, Ahmed Bedru, Lema, Tsehaynesh, Demissie, Tesfaye Moti, Tekletsion, Yenenesh, Worku, Alemayehu, Xabher, Haimanot Guebre, Yamuah, Lawrence, Boukary, Rahamatou Moustapha, Collard, Jean-Marc, Dan Dano, Ibrahim, Habiboulaye, Ibrahim, Issaka, Bassira, Jusot, Jean-François, Ousmane, Sani, Rabe, Issoufa, Dauglaz, Doumagoum Moto, Gami, Jean Pierre, Gamougam, Kadidja, Mbainadji, Lodoum, Naibei, Nathan, Narbé, Maxime, Toralta, Jacques, Berthe, Abdoulaye, Diallo, Kanny, Keita, Mahamadou, Coulibaly, Adama, Onwuchekwa, Uma, Sow, Samba O, Tamboura, Boubou, Traore, Awa, Toure, Aliou, Clark, Tom, Mayer, Leonard, Amodu, Mary, Beida, Omeiza, Gadzama, Galadima, Omotara, Babatunji, Zailani, Sambo, Yahya, Shuaibu, Chandramohan, Daniel, Greenwood, Brian M, Hassan-King, Musa, Manigart, Olivier, Nascimento, Maria, M Stuart, James, Woukeu, Arouna, Basta, Nicole E, Bai, Xilian, Borrow, Ray, Findlow, Helen, Alavo, Serge, Bassene, Hubert, Diallo, Aldiouma, Dieng, Marietou, Doucouré, Souleymane, Gomis, Jules François, Ndiaye, Assane, Sokhna, Cheikh, Trape, Jean François, Bugri, Akalifa, Forgor, Abudulai, Hodgson, Abraham, Osei, Isaac, Quaye, Stephen L, Williams, John, Wontuo, Peter, Irving, Thomas, Trotter, Caroline L, Karachaliou, Andromachi, Bennett, Julia, Hill, Dorothea, Harrison, Odile, Maiden, Martin C, Rebbetts, Lisa, and Watkins, Eleanor

Published
2016
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19. Pharyngeal carriage of Neisseria species in the African meningitis belt

Author

Diallo, Kanny, Trotter, Caroline, Timbine, Youssouf, Tamboura, Boubou, Sow, Samba O., Issaka, Bassira, Dano, Ibrahim D., Collard, Jean-Marc, Dieng, Marietou, Diallo, Aldiouma, Mihret, Adane, Ali, Oumer A., Aseffa, Abraham, Quaye, Stephen L., Bugri, Akalifa, Osei, Isaac, Gamougam, Kadidja, Mbainadji, Lodoum, Daugla, Doumagoum M., Gadzama, Galadima, Sambo, Zailani B., Omotara, Babatunji A., Bennett, Julia S., Rebbetts, Lisa S., Watkins, Eleanor R., Nascimento, Maria, Woukeu, Arouna, Manigart, Olivier, Borrow, Ray, Stuart, James M., Greenwood, Brian M., and Maiden, Martin C.J.

Published
2016
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27. Molecular diagnosis of urogenital schistosomiasis in pre-school children, school-aged children and women of reproductive age at community level in central Senegal

Author

Sow, Doudou, primary, Sylla, Khadime, additional, Dieng, Ndeye Marème, additional, Senghor, Bruno, additional, Gaye, Papa Mouhamadou, additional, Fall, Cheikh B., additional, Goumballa, Ndiaw, additional, Diallo, Aldiouma, additional, Ndiaye, Jean Louis A., additional, Parola, Philippe, additional, Sokhna, Cheikh, additional, Doucouré, Souleymane, additional, and Faye, Babacar, additional

Published
2022
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29. Hepatitis B in Senegal: A Successful Infant Vaccination Program but Urgent Need to Scale Up Screening and Treatment (ANRS 12356 AmBASS survey)

Author

Périères, Lauren, Diallo, Aldiouma, Marcellin, Fabienne, Nishimwe, Marie Libérée, Ba, El Hadji, Coste, Marion, Lo, Gora, Halfon, Philippe, Touré Kane, Coumba, Maradan, Gwenaëlle, Carrieri, Patrizia, Diouf, Assane, Shimakawa, Yusuke, Sokhna, Cheikh, Boyer, Sylvie, Bérenger, Cyril, Bousmah, Marwan al Qays, de Seze, Maëlle, Djaogol, Tchadine, Treibich, Carole, Ba, Elhadji, Dièye, Fambaye, Faye, Elhadji Bilal, Ndiaye, Assane, Sow, Mouhamadou Baba, Ndiaye, Anna Julienne Selbé, Ndiour, Samba, Mohamed, Sofiane, Rouveau, Nicolas, Cortès, Maria‐Camila Calvo, Laborde‐Balen, Gabrièle, Audibert, Martine, Fall, Fatou, Gueye, Ibrahima, Lacombe, Karine, Seydi, Moussa, Tuaillon, Edouard, Vray, Muriel, Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des sciences de la santé publique [Marseille] (ISSPAM), Aix-Marseille Sciences Economiques (AMSE), École des hautes études en sciences sociales (EHESS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche en Santé, de Surveillance Épidémiologique et de Formation [Dakar, Sénégal] (IRESSEF), ALPHABIO - Laboratoire de biologie médicale, Hôpital Européen [Fondation Ambroise Paré - Marseille], Observatoire régional de la santé Provence-Alpes-Côte d'Azur [Marseille] (ORS PACA), Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Université Paris Cité (UPCité)-Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Paris Cité (UPCité)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), ANRS 12356 AmBASS Survey Study Group: Cyril Bérenger, Marwan Al Qays Bousmah, Sylvie Boyer, Patrizia Carrieri, Marion Coste, Maëlle de Seze, Tchadine Djaogol, Gwenaëlle Maradan, Fabienne Marcellin, Carole Treibich, Elhadji Ba, Aldiouma Diallo, Fambaye Dièye, Assane Diouf, Elhadji Bilal Faye, Assane Ndiaye, Lauren Périères, Cheikh Sokhna, Mouhamadou Baba Sow, Coumba Touré Kane, Gora Lo, Anna Julienne Selbé Ndiaye, Samba Ndiour, Philippe Halfon, Sofiane Mohamed, Nicolas Rouveau, Maria-Camila Calvo Cortès, Gabrièle Laborde-Balen, Martine Audibert, Fatou Fall, Ibrahima Gueye, Karine Lacombe, Moussa Seydi, Yusuke Shimakawa, Edouard Tuaillon, Muriel Vray, Lhuillier, Elisabeth, and Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA)

Subjects
Adult, Hepatitis B Surface Antigens, Adolescent, Hepatology, Vaccination, Infant, Hepatitis B, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, Senegal, 3. Good health, Young Adult, 03 medical and health sciences, Cross-Sectional Studies, 0302 clinical medicine, Humans, Female, Hepatitis B Vaccines, 030211 gastroenterology & hepatology, 030212 general & internal medicine, [SHS.ECO] Humanities and Social Sciences/Economics and Finance, Child
Abstract

International audience; Senegal introduced the infant hepatitis B virus (HBV) vaccination in 2004 and recently committed to eliminating hepatitis B by 2030. Updated epidemiological data are needed to provide information on the progress being made and to develop new interventions. We estimated the prevalence of hepatitis B surface antigen (HBsAg) in children and adults living in rural Senegal and assessed hepatitis B treatment eligibility. A cross-sectional population-based serosurvey of HBsAg was conducted in 2018-2019 in a large sample (n = 3,118) of residents living in the Niakhar area (Fatick region, Senegal). Individuals positive for HBsAg subsequently underwent clinical and biological assessments. Data were weighted for age and sex and calibrated to be representative of the area's population. Among the 3,118 participants, 206 were HBsAg positive (prevalence, 6.9%; 95% confidence interval [CI], 5.6-8.1). Prevalence varied markedly according to age group in individuals aged 0-4, 5-14, 15-34, and >= 35 years as follows: 0.0% (95% CI, 0.00-0.01); 1.5% (95% CI, 0.0-2.3); 12.4% (95% CI, 9.1-15.6); and 8.8% (95% CI, 6.1-11.5), respectively. Of those subsequently assessed, 50.9% (95% CI, 41.8-60.0) had active HBV infection; 4 (2.9%; 95% CI, 0.9-9.4) were eligible for hepatitis B treatment. Conclusion: In this first population-based serosurvey targeting children and adults in rural Senegal, HBsAg prevalence was very low in the former, meeting the World Health Organization's (WHO) < 1% HBsAg 2020 target; however, it was high in young adults (15-34 years old) born before the HBV vaccine was introduced in 2004. To reach national and WHO hepatitis elimination goals, general population testing (particularly for adolescents and young adults), care, and treatment scale-up need to be implemented.

Published
2021

30. Rethinking the management of chronic hepatitis B in the context of rural sub-saharan Africa: results from a social justice mixed methods study in rural Senegal (the AmBASS-PeCSen study)

Author

Coste, Marion, Ndong, Cilor, Diallo, Aldiouma, Diouf, Assane, Boyer, Sylvie, Prah, Jennifer, Aix-Marseille Sciences Economiques (AMSE), École des hautes études en sciences sociales (EHESS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Pennsylvania State University (Penn State), Penn State System, Perelman School of Medicine, University of Pennsylvania, Lhuillier, Elisabeth, and Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA)

Subjects
Hepatology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, [SHS.ECO] Humanities and Social Sciences/Economics and Finance, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
Abstract

International audience

Published
2022

31. Hepatitis B in Senegal: A Successful Infant Vaccination Program but Urgent Need to Scale Up Screening and Treatment (ANRS 12356 AmBASS survey)

Author

Périères, Lauren, primary, Diallo, Aldiouma, additional, Marcellin, Fabienne, additional, Nishimwe, Marie Libérée, additional, Ba, El Hadji, additional, Coste, Marion, additional, Lo, Gora, additional, Halfon, Philippe, additional, Kane, Coumba Touré, additional, Maradan, Gwenaëlle, additional, Carrieri, Patrizia, additional, Diouf, Assane, additional, Shimakawa, Yusuke, additional, Sokhna, Cheikh, additional, and Boyer, Sylvie, additional

Published
2022
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32. Breastfeeding and Growth in Rural Senegalese Toddlers

Author

Simondon, Kirsten B., Diallo, Aldiouma, Simondon, Franqois, Back, Nathan, editor, Cohen, Irun R., editor, Kritchevsky, David, editor, Lajtha, Abel, editor, Paoletti, Rodolfo, editor, Koletzko, Berthold, editor, Michaelsen, Kim Fleischer, editor, and Hernell, Olle, editor

Published
2002
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36. A classification method for binary predictors combining similarity measures and mixture models

Author

Sylla Seydou N., Girard Stéphane, Diongue Abdou Ka, Diallo Aldiouma, and Sokhna Cheikh

Subjects
mixture model, binary predictors, kernel method, similarity measure, Science (General), Q1-390, Mathematics, QA1-939
Abstract

In this paper, a new supervised classification method dedicated to binary predictors is proposed. Its originality is to combine a model-based classification rule with similarity measures thanks to the introduction of new family of exponential kernels. Some links are established between existing similarity measures when applied to binary predictors. A new family of measures is also introduced to unify some of the existing literature. The performance of the new classification method is illustrated on two real datasets (verbal autopsy data and handwritten digit data) using 76 similarity measures.

Published
2015
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37. Draft genomes and descriptions of Urmitella timonensis gen. nov., sp. nov. and Marasmitruncus massiliensis gen. nov., sp. nov., isolated from severely malnourished African children using culturomics

Author

Bellali, Sara, Haddad, Gabriel, Pham, Thi-Phuong-Thao, Iwaza, Rim, Ibrahim, Ahmad, Armstrong, Nicholas, Fadlane, Amael, Couderc, Carine, Diallo, Aldiouma, Sokhna, Cheikh, Million, Matthieu, Raoult, Didier, Tidjani Alou, Maryam, Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Vecteurs - Infections tropicales et méditerranéennes (VITROME), and Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA)

Subjects
DNA, Bacterial, Culturomics, Urmitella timonensis, MESH: Humans, [SDV]Life Sciences [q-bio], Taxono-genomics, MESH: DNA, Bacterial, MESH: RNA, Ribosomal, 16S, New taxa, MESH: Child, RNA, Ribosomal, 16S, Marasmitruncus massiliensis, Humans, Female, MESH: Phylogeny, Child, MESH: Female, Human gut microbiota, Phylogeny
Abstract

International audience; Abstract Two strains, designated as Marseille-P2918 T and Marseille-P3646 T , were isolated from a 14-week-old Senegalese girl using culturomics: Urmitella timonensis strain Marseille-P2918 T (= CSUR P2918, = DSM 103634) and Marasmitruncus massiliensis strain Marseille-P3646 T (= CSUR P3646, = CCUG72353). Both strains were rod-shaped, anaerobic, spore forming motile bacteria. The 16S rRNA gene sequences of strains Marseille-P2918 T (LT598554) and Marseille-P3646 T (LT725660) shared 93.25% and 94.34% identity with Tissierella praeacuta ATCC 25539 T and Anaerotruncus colihominis CIP 107754 T , their respective phylogenetically closest species with standing in nomenclature. Therefore, strain Marseille-P2918 T is classified within the family Tissierellaceae and order Tissierellales whereas strain Marseille-P3646 T is classified within the family Oscillospiraceae and order Eubacteriales . The genome of strain Marseille-P2918 T had a size of 2.13 Mb with a GC content of 50.52% and includes six scaffolds and six contigs, and that of strain Marseille-P3646 T was 3.76 Mbp long consisting of five contigs with a 50.04% GC content. The genomes of both strains presented a high percentage of genes encoding enzymes involved in genetic information and processing, suggesting a high growth rate and adaptability. These new taxa are extensively described and characterised in this paper, using the concept of taxono-genomic description.

Published
2021

39. Social contact patterns and implications for infectious disease transmission – a systematic review and meta-analysis of contact surveys

Author

Mousa, Andria, primary, Winskill, Peter, additional, Watson, Oliver John, additional, Ratmann, Oliver, additional, Monod, Mélodie, additional, Ajelli, Marco, additional, Diallo, Aldiouma, additional, Dodd, Peter J, additional, Grijalva, Carlos G, additional, Kiti, Moses Chapa, additional, Krishnan, Anand, additional, Kumar, Rakesh, additional, Kumar, Supriya, additional, Kwok, Kin O, additional, Lanata, Claudio F, additional, de Waroux, Olivier Le Polain, additional, Leung, Kathy, additional, Mahikul, Wiriya, additional, Melegaro, Alessia, additional, Morrow, Carl D, additional, Mossong, Joël, additional, Neal, Eleanor FG, additional, Nokes, D James, additional, Pan-ngum, Wirichada, additional, Potter, Gail E, additional, Russell, Fiona M, additional, Saha, Siddhartha, additional, Sugimoto, Jonathan D, additional, Wei, Wan In, additional, Wood, Robin R, additional, Wu, Joseph, additional, Zhang, Juanjuan, additional, Walker, Patrick, additional, and Whittaker, Charles, additional

Published
2021
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40. Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey)

Author

Périères, Lauren, Marcellin, Fabienne, Lo, Gora, Protopopescu, Camelia, Ba, El, Coste, Marion, Kane, Coumba Touré, Maradan, Gwenaëlle, Diallo, Aldiouma, Sokhna, Cheikh, Boyer, Sylvie, and Group, on behalf of the ANRS 12356 AmBASS Survey Study

Subjects
vaccination timeliness, vaccination coverage, pentavalent vaccination, birth dose vaccination, Medicine, hepatitis B vaccine, Senegal
Abstract

Detailed knowledge about hepatitis B virus (HBV) vaccination coverage and timeliness for sub-Saharan Africa is scarce. We used data from a community-based cross-sectional survey conducted in 2018–2019 in the area of Niakhar, Senegal, to estimate coverage, timeliness, and factors associated with non-adherence to the World Health Organisation-recommended vaccination schedules in children born in 2016 (year of the birth dose (BD) introduction in Senegal) and 2017–2018. Vaccination status was assessed from vaccination cards, surveillance data, and healthcare post vaccination records. Among 241 children with available data, for 2016 and 2017–2018, respectively, 31.0% and 66.8% received the BD within 24 h of birth (BD schedule), and 24.3% and 53.7% received the BD plus at least two pentavalent vaccine doses within the recommended timeframes (three-dose schedule). In logistic regression models, home birth, dry season birth, and birth in 2016 were all associated with non-adherence to the recommended BD and three-dose schedules. Living over three kilometres from the nearest healthcare post, being the firstborn, and living in an agriculturally poorer household were only associated with non-adherence to the three-dose schedule. The substantial proportion of children not vaccinated according to recommended schedules highlights the importance of considering vaccination timeliness when evaluating vaccination programme effectiveness. Outreach vaccination activities and incentives to bring children born at home to healthcare facilities within 24 h of birth, must be strengthened to improve timely HBV vaccination.

Published
2021

41. Author response: Social contact patterns and implications for infectious disease transmission – a systematic review and meta-analysis of contact surveys

Author

Mousa, Andria, primary, Winskill, Peter, additional, Watson, Oliver John, additional, Ratmann, Oliver, additional, Monod, Mélodie, additional, Ajelli, Marco, additional, Diallo, Aldiouma, additional, Dodd, Peter J, additional, Grijalva, Carlos G, additional, Kiti, Moses Chapa, additional, Krishnan, Anand, additional, Kumar, Rakesh, additional, Kumar, Supriya, additional, Kwok, Kin O, additional, Lanata, Claudio F, additional, de Waroux, Olivier Le Polain, additional, Leung, Kathy, additional, Mahikul, Wiriya, additional, Melegaro, Alessia, additional, Morrow, Carl D, additional, Mossong, Joël, additional, Neal, Eleanor FG, additional, Nokes, D James, additional, Pan-ngum, Wirichada, additional, Potter, Gail E, additional, Russell, Fiona M, additional, Saha, Siddhartha, additional, Sugimoto, Jonathan D, additional, Wei, Wan In, additional, Wood, Robin R, additional, Wu, Joseph, additional, Zhang, Juanjuan, additional, Walker, Patrick, additional, and Whittaker, Charles, additional

Published
2021
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42. RETRACTED ARTICLE: Increased Gut Redox and Depletion of Anaerobic and Methanogenic Prokaryotes in Severe Acute Malnutrition

Author

Million, Matthieu, Tidjani Alou, Maryam, Khelaifia, Saber, Bachar, Dipankar, Lagier, Jean-Christophe, Dione, Niokhor, Brah, Souleymane, Hugon, Perrine, Lombard, Vincent, Armougom, Fabrice, Fromonot, Julien, Robert, Catherine, Michelle, Caroline, Diallo, Aldiouma, Fabre, Alexandre, Guieu, Régis, Sokhna, Cheikh, Henrissat, Bernard, Parola, Philippe, and Raoult, Didier

Published
2016
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43. A Listeria monocytogenes clone in human breast milk associated with severe acute malnutrition in West Africa: A multicentric case-controlled study

Author

Sarr, Marièma, primary, Tidjani Alou, Maryam, additional, Delerce, Jeremy, additional, Khelaifia, Saber, additional, Diagne, Nafissatou, additional, Diallo, Aldiouma, additional, Bassene, Hubert, additional, Bréchard, Ludivine, additional, Bossi, Vincent, additional, Mbaye, Babacar, additional, Lagier, Jean-Christophe, additional, Levasseur, Anthony, additional, Sokhna, Cheikh, additional, Million, Matthieu, additional, and Raoult, Didier, additional

Published
2021
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44. The Costs of Introducing the Hepatitis B Birth Dose Vaccine into the National Immunization Programme in Senegal (NéoVac Study)

Author

Gosset, Andréa, primary, Nishimwe, Marie Libérée, additional, Diallo, Mamadou Yaya, additional, Deroo, Lucas, additional, Diallo, Aldiouma, additional, Ba, El Hadji, additional, Carrieri, Patrizia Maria, additional, Sokhna, Cheikh, additional, Vray, Muriel, additional, Shimakawa, Yusuke, additional, and Boyer, Sylvie, additional

Published
2021
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45. Sibling status, home birth, tattoos and stitches are risk factors for chronic hepatitis B virus infection in Senegalese children: A cross‐sectional survey

Author

Périères, Lauren, Protopopescu, Camelia, Lo, Gora, Marcellin, Fabienne, Ba, El Hadji, Coste, Marion, Touré Kane, Coumba, Diallo, Aldiouma, Sokhna, Cheikh, Boyer, Sylvie, Anrs 12356 Ambass Survey Study, Grp, Bérenger, Cyril, Bousmah, Marwân-Al-Qays, Carrieri, Patrizia, de Sèze, Maëlle, Djaogol, Tchadine, Maradan, Gwenaëlle, Treibich, Carole, Ba Ba, El Hadji, Dièye, Fambaye, Diouf, Assane, Faye, Elhadji Bilal, Ndiaye, Assane, Sow, Mouhamadou Baba, Ndiaye, Anna Julienne Selbé, Ndiour, Samba, Halfon, Philippe, Mohamed, Sofiane, Rouveau, Nicolas, Cortès, Maria‐camila Calvo, Laborde‐balen, Gabrièle, Audibert, Martine, Fall, Fatou, Gueye, Ibrahima, Lacombe, Karine, Seydi, Moussa, Shimakawa, Yusuke, Tuaillon, Edouard, Vray, Muriel, Maladies infectieuses persistantes et émergentes en Afrique de l’Ouest [Dakar, Sénégal] (Equipe 3 - VITROME), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, de Surveillance Épidémiologique et de Formation [Dakar, Sénégal] (IRESSEF), Aix-Marseille Sciences Economiques (AMSE), École des hautes études en sciences sociales (EHESS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA), The AmBASS research project was funded in full by the French ANRS Emerging Infectious Diseases research agency under the auspices of the French National Institute for Health and Medical Research (INSERM) (INSERM-ANRS), grant number 12356., Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Pathogenesis and Control of Chronic and Emerging Infections (PCCEI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Université des Antilles (UA)-Etablissement français du don du sang [Montpellier], Lhuillier, Elisabeth, and École des hautes études en sciences sociales (EHESS)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)

Subjects
HBsAg, Cross-sectional study, medicine.disease_cause, 0302 clinical medicine, Pregnancy, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Infection control, risk factors, 030212 general & internal medicine, [SHS.ECO] Humanities and Social Sciences/Economics and Finance, Home Childbirth, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, child, Tattooing, virus diseases, Hepatitis B, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, Senegal, 3. Good health, Vaccination, Infectious Diseases, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Female, 030211 gastroenterology & hepatology, Hepatitis B virus, prevalence, 03 medical and health sciences, Hepatitis B, Chronic, Virology, medicine, Humans, Hepatitis B Vaccines, Sibling, Aged, Hepatitis B Surface Antigens, Hepatology, business.industry, Siblings, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Infectious Disease Transmission, Vertical, digestive system diseases, Cross-Sectional Studies, hepatitis B, business, Home birth, Demography
Abstract

International audience; Sub-Saharan Africa's hepatitis B virus (HBV) burden is primarily due to infection in infancy. However, data on chronic HBV infection prevalence and associated risk factors in children born post-HBV vaccination introduction are scarce. We estimated hepatitis B surface antigen (HBsAg) prevalence and risk factors in Senegalese children born during the HBV vaccination era. In 2018-2019, a community-based cross-sectional survey was conducted in Senegal among children born between 2004 and 2015 (ie after the three-dose HBV vaccine series was introduced (2004) but before the birth dose's introduction (2016)). HBsAg-positive children were identified using dried blood spots. A standardized questionnaire collected socioeconomic information. Data were age-sex weighted and calibrated to be representative of children living in the study area. Risk factors associated with HBsAg positivity were identified using negative binomial regression. Among 1,327 children, 17 were HBsAg-positive (prevalence = 1.23% (95% confidence interval [CI] 0.61-1.85)). Older age (adjusted incidence-rate ratio [aIRR] 1.31 per one-year increase, 95% CI 1.10-1.57), home vs healthcare facility delivery (aIRR 3.55, 95% CI 1.39-9.02), stitches (lifetime) (aIRR 4.79; 95% CI 1.84-12.39), tattoos (aIRR 8.97, 95% CI 1.01-79.11) and having an HBsAg-positive sibling with the same mother (aIRR 3.05, 95% CI 1.09-8.57) were all independently associated with HBsAg positivity. The low HBsAg prevalence highlights the success of the Senegalese HBV vaccination program. To further reduce HBV acquisition in children, high-risk groups, including pregnant women and siblings of HBsAg-positive individuals, must be screened. Vital HBV infection prevention measures include promoting delivery in healthcare facilities, and increasing awareness of prevention and control procedures.

Published
2021

46. Annexe 18.1. Les essais cliniques dans l’Observatoire de Niakhar

Author

Diallo, Aldiouma and Sokhna, Cheikh

Abstract

Les premières études effectuées par l’IRD dans la zone de Niakhar ont concerné la collecte de données démographiques. Cette zone qui s’étendait sur huit villages au début a été élargie par la suite pour couvrir 30 villages avec une plus grande population en 1983. Cette dernière évolution du site a permis de recueillir des données épidémiologiques qui ont contribué à établir des indicateurs de santé notamment sur la rougeole, le paludisme, la coqueluche, la malnutrition, le tétanos, etc. Le si...

Published
2020

47. Annexe 12.1. De la surveillance épidémiologique à l’intervention

Author

Diallo, Aldiouma

Abstract

La méningite est provoquée par les bactéries Neisseria meningitidis (méningocoques). Les symptômes les plus fréquents de la méningite à méningocoques sont fièvre et frissons, céphalées, raideur de nuque, léthargie et somnolence, ou irritabilité. La période d’incubation se situe entre 2 et 10 jours et elle est en moyenne de 4 jours. La transmission des bactéries se fait par le transfert de sécrétions provenant du nez ou de la gorge lors de contacts étroits ou intimes. En l’absence de traitemen...

Published
2020

48. Chapitre 7. Cinquante ans de transition de la mortalité à Niakhar (1963-2012)

Author

Garenne, Michel, Cantrelle, Pierre, Delaunay, Valérie, Becker, Charles, Douillot, Laetitia, Dione, Djibril, Diallo, Aldiouma, and Sokhna, Cheikh

Subjects
SOC006000, instrument de collecte, paludisme, Area Studies, Anthropology, développement durable, éthique, observatoire, population, santé, société, JHBD, Demography
Abstract

Introduction Ce chapitre traite des tendances de la mortalité à Niakhar au cours des 50 ans du suivi démographique (1963-2012). Il s’agit d’un sujet complexe, qui mériterait des analyses plus approfondies que celle qui est présentée ci-dessous. Cette étude ne fournit que les principaux éléments des grandes tendances observées à Niakhar au cours du demi-siècle. Cette analyse est présentée dans un cadre plus général, avec une mise en perspective géographique des grandes tendances de mortalité a...

Published
2020

49. Niakhar, mémoires et perspectives

Author

Adjamagbo, Agnès, Audouin, Élise, Awono, Théophile, Ba, Marame, Badji, Amadou, Badji, Mamadou, Bassène, Hubert, Ba Gning, Sadio, Becker, Charles, Binta Diémé, Ndéye, Bonnet, Doris, Bork, Kirsten, Bourgoin, Jérémy, Brasseur, Philippe, Cantrelle, Pierre, Chabrol, Fanny, Chippaux, Jean-Philippe, Cissé, Badara, Collignon, René, Coll Seck, Awa Marie, Daff, Bocar Mamadou, Delaunay, Valérie, Desclaux, Alice, Diallo, Aldiouma, Diatta, Georges, Diatte, Samba, Dione, Djibril, Diouf, Ibrahima, Diouf, Pape Niokhor, Douillot, Laetitia, Engeli, Emmanuelle, Étard, Jean-François, Fall, Abdou Salam, Fall, Bassirou, Faye, Ernest, Fenollar, Florence, François Trape, Jean, Garenne, Michel, Guénard, Charlotte, Helleringer, Stéphane, Lalou, Richard, Ly Wane, Coudy, Masquelier, Bruno, Masse, Dominique, Mbacké, Cheik, Mediannikov, Oleg, Moatti, Jean-Paul, Mondain, Nathalie, Moulin, Anne Marie, Moullet, Aurore, Ndao, Pap, Ndiaye, Émile, Ndiaye, Émilie, Ndiaye, Ousmane, Ndiaye, Samba, Ndiaye Coly, Aminata, Ndour Badiane, Yacine, Niokhor Diouf, Pape, Ouvrier, Ashley, Parola, Philippe, Pison, Gilles, Raoult, Didier, Roquet, Dominique, Sandberg, John, Sauvain-Dugerdil, Claudine, Senghor, Paul, Sokhna, Cheikh, Tidiane Ndiaye, Cheikh, Tine, Cheikh, Tousignant, Noémi, Tousignant, Noémie, Vayssières, Jonathan, Vidal, Laurent, Delaunay, Valérie, Desclaux, Alice, and Sokhna, Cheikh

Subjects
SOC006000, instrument de collecte, paludisme, Area Studies, Anthropology, développement durable, éthique, observatoire, population, santé, société, JHBD, Demography
Abstract

Fondé en 1962 en zone rurale à 150 km de Dakar, en pays Sereer, l'observatoire de Niakhar est le plus ancien observatoire de population en Afrique encore en activité. Au cœur d'une histoire scientifique et humaine originale, il a permis d'assurer, depuis sa création, le suivi sanitaire, démographique, social, économique et environnemental de plus de deux générations. Les résultats de recherche de Niakhar, avec des indicateurs suivis dans le temps long, ont éclairé et accompagné les politiques nationales et internationales en matière de santé, notamment pour la prévention du paludisme. En revisitant 50 années de recherche sur le site de Niakhar, cet ouvrage décrit et analyse la construction de cette plate-forme d'observation prospective pluridisciplinaire. Il illustre l'intérêt de l'approche sur le long terme dans les différents domaines de recherche et ouvre une réflexion sur les enjeux éthiques particuliers à cet instrument de collecte. Enfin, il propose des pistes d'évolution méthodologique et de gouvernance pour la recherche. Cette première synthèse sur l'observatoire de Niakhar permettra à l'État sénégalais et aux décideurs ouest-africains, avec les institutions internationales et les scientifiques, de disposer de bases concrètes pour optimiser ces plates-formes de recherche et les mobiliser dans la perspective des objectifs de développement durable.

Published
2020

50. Chapitre 11. Durée de l’allaitement maternel et risque de malnutrition de l’enfant

Author

Bork, Kirsten, Ndiaye Coly, Aminata, Ly Wane, Coudy, Diouf, Pape Niokhor, and Diallo, Aldiouma

Subjects
SOC006000, instrument de collecte, paludisme, Area Studies, Anthropology, développement durable, éthique, observatoire, population, santé, société, JHBD, Demography
Abstract

En 1988, une revue médicale prestigieuse a publié un article montrant une relation statistique entre allaitement prolongé et malnutrition chez des enfants ghanéens (Brakohiapa et al. 1988). Dans un échantillon de 202 enfants âgés de 12 à 24 mois hospitalisés à Accra, la proportion d’enfants allaités était plus élevée parmi ceux atteints d’une malnutrition aiguë (faible corpulence) que parmi ceux en bon état nutritionnel. Ensuite, les auteurs ont procédé à une expérimentation dans un village p...

Published
2020

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