1. 1-Methyl-1H-1,2,4-triazole as the main marker of 1,1-dimethylhydrazine exposure in plants.
- Author
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Karnaeva AE, Milyushkin AL, Khesina ZB, and Buryak AK
- Subjects
- Humans, Reproducibility of Results, Triazoles, Dimethylhydrazines pharmacology, Lepidium sativum
- Abstract
With their wide application in chemical industry, human health and environmental toxic effects of hydrazines arise extensive concerns. Although hydrazine exposure is known to lead to inhibition of seed germination and seedling growth in plants, there are few reports about the mechanism of oxidation or transformation ways of hydrazines in plant tissue. In this research, garden cress (Lepidium sativum L.) and zucchini (Cucurbita pepo L.) were used as model plant objects to study 1,1-dimethylhydrazine exposure in vitro using the GC-MS system. The seed germination and plant growth experiments were carried out in Petri dishes using an aqueous media. Among the detected 1,1-dimethylhydrazine transformation products in plant tissues, 1-methyl-1H-1,2,4-triazole had the highest intensity and reproducibility. In our research, 1-methyl-1H-1,2,4-triazole formed at all contaminant concentrations in an extremely short period. This preliminary study determined 1,1-dimethylhydrazine environment contamination by detecting 1-methyl-1H-1,2,4-triazole in combination with other transformation products., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
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