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Scorpions (Arachnida: Scorpions) are one of the medically important oldest arthropods. They have been one of the humans' interests in terms of special morphology, painful stings, mortality, and behavioral attractions for many years. Diagnosis of scorpions is based on morphological characteristics and molecular methods. But, one of the most important and fundamental problems of identifying the Iranian scorpions is the lack of a comprehensive method. Due to the fact that a relatively long time has not passed since the classification of scorpions in Iran and there are no definitive divisions about the genera and species in the country, the current pictorial key was provided to identify the Iranian scorpions. In this study, various methods were used to catch the scorpions. For preparing the pictorial key, different genera of scorpions were collected from urban, rural, plain, and mountain areas in different parts of Iran as well as some archived specimens from the medical arachnid's Museum of Shiraz University of Medical Sciences were used from 2010 to 2020 collection boxes. The key presented in this study was prepared only based on morphological features. It was necessary to remind a few points about this key and its use. Considering the above-mentioned points, this key was provided for 16 genera, 64 species, and 3 families of Iranian scorpions, and the results of other researchers are included in it. The study of various aspects of scorpion life, especially faunistic studies has been recently considered in Iran. Various methods such as molecular methods and composition of scorpion venom can be used for classification, the most common of which are morphological features that have a long history. Therefore, the need to provide a key to detect scorpions in the country has a special priority. [ABSTRACT FROM AUTHOR]

Background: Since the beginning of 2020, the world has been grappling with a common problem, the coronavirus or COVID-19, causing a significant increase in worry, anxiety, and stress worldwide. In Iran, the rapid spread of the COVID-19 virus has posed serious threats to individuals' physical and mental health. Due to their extensive physical contact with infected individuals, medical staff experience high anxiety levels compared to other members of society. Objectives: The present study aimed to investigate the effectiveness of the acceptance and commitment approach on the resilience, self-compassion, and corona disease anxiety of medical staff involved in the COVID-19 response in Hamadan, Iran. Methods: This study utilized a semi-experimental design, including pre-test, post-test, follow-up, and control group. The study population included all medical staff involved in the COVID-19 response in Hamadan in 2021. From this population, 40 individuals were purposively selected and randomly assigned to either the experimental or control groups (20 participants in each group). Before the intervention, both groups underwent measurements (pre-test) using the Connor and Davidson Resilience Questionnaire (2003), the Neff Self-Compassion Scale (2003), and Alipouret al.'s Corona Disease Anxiety Questionnaire (2018). After the intervention of acceptance and commitment therapy for the experimental group, the same tests were conducted again for both groups (post-test). Finally, three months later, the same measurements were repeated for both groups (follow-up). The data were analyzed using repeated measures analysis of variance in SPSS-25. Results: The findings demonstrated the significant impact of acceptance and commitment therapy in enhancing resilience (P ≤ 0.001) and self-compassion (P ≤ 0.001), as well as reducing COVID-19 anxiety among the medical staff in Hamadan (P ≤ 0.001). Moreover, these effects remained stable during the follow-up phase. Conclusions: The results underscore the importance of utilizing acceptance and commitment therapy to enhance resilience and self-compassion while reducing anxiety among medical staff managing the disease. Additionally, hospital educational and executive managers should prioritize training medical staff in acceptance and commitment skills to effectively address COVID-19 anxiety. [ABSTRACT FROM AUTHOR]

Since the beginning of life on earth, mankind has always used animals and plants for its nutrition and has continuously trained and developed them for their benefits and social, cultural, and economic needs. In the past, livestock and crop breeding were done by traditional farmers and ranchers. It improves the performance of livestock and crops, they performed the selection, which is one of the principles of plant breeding and livestock breeding. They made this choice with the help of information that was passed down to them from successive generations. It is a participatory plant breeding and production of crops with the help of researchers alongside farmers. Farmers work with researchers, scientists, and other stakeholders -even consumers-to improve crops and develop resilient plant varieties. Farmers are aware of their needs and have a conscious understanding of their agricultural land in terms of soil type, seed type, weather conditions, surface water, underground water conditions, etc. Therefore, they can play an important role in making decisions about the implementation of plant breeding and the type of planting pattern in the cultivated microclimates. In other words, farmers determine their cultivation goals based on their environments, conditions, tastes, and local cultures. The seed that is obtained in this way by the breed researchers with the help of the leading farmers, actually contributes significantly to the food governance of the people of that region and that country. [ABSTRACT FROM AUTHOR]

The distribution of wealth among the people of society is one of the most important subject in the economy, distribution and its methods keep the economic balance among the people of the society. Therefore, fair distribution of wealth leads to the welfare and comfort of all people in society. Distribution theory has been remained a hot discussion and argument among the different economic schools for a long time. Capitalism believes in the freedom of the individual in all areas, the general law in the capitalist system is that each production factor determines its part in wealth. The factors of production are land, workforce, capital and employment. The theory of capitalism in the domain of the division of wealth is that that the land gets lease or rent, the workforce gets wages, capital gains profit and the employer gains benefit. Socialists believe that the equal distribution of wealth is the key solution to all the problems of society and argue: Due to the lack of reasonable distribution of wealth, numerous major problems raised in society. According to socialists, in fact the unequal distribution of wealth in a society is the basic reason of all economic problems among the people of society. They suggest that all tools and factors of production should be taken from individuals and should be controlled by government. The people of society should have fair access to the wealth produced from it, and the government itself should have a mechanism for wealth distribution. However, the Islamic economic system has another theory. Its crux is: the variance in the wealth of the people of the society is a natural matter, all human beings are not equal in wealth. Distribution from the perspective of the Islamic economy has three stages: The first stage is possession of items, the second stage is the distribution based on the contribution of each production factor in wealth production and the third stage is the redistribution of wealth distribution by some distributing mechanism. [ABSTRACT FROM AUTHOR]

Background: In severe COVID-19 cases, a hypercoagulable state may occur. Antiphospholipid syndrome-related auto-antibodies (APSRAs) contribute to coagulopathy, but their role in COVID-19 remains unclear. We aimed to investigate the prevalence of positive APSRAs and their effect on clinical outcomes in confirmed COVID-19 patients. Materials and Methods: In this cross-sectional study, severe hospitalized COVID-19 cases were enrolled. Demographic and clinical data were obtained from the day of admission. APSRAs including IgG and/or IgM anticardiolipin (aCL) and anti-ß2-glycoprotein1 (anti-ß2GP1) as well as lupus anticoagulant (LAC) were measured. Results: In this study, 54 severe COVID-19 cases with positive RT-PCR and chest CT scans were recruited. Positive APSRAs were found in 7 (12.9%) patients. Positive LAC was a more prevalent marker as compared to other tests (11.1%). The prevalence of positive aCL (IgM or IgG) and anti-ß2 GPI (IgM or IgG) w as 1.8% (in an elderly woman). Lower oxygen saturation was found in the positive APSRAs group as opposed to the negative APSRAs group (70.3±9 vs. 84.8±9.7%). The mortality rate in the positive APSRAs group was significantly higher relative to the negative APSRAs group (83.3% vs. 27.1%; Pvalue: 0.01). Likewise, the mechanical ventilation requirement in the positive group was also higher (50% vs. 27.1%, P-value: 0.28). Conclusion: This study indicated that LAC might be associated with critical cases and high mortality of COVID-19. Nonetheless, the mortality was not related to macrothrombotic incidence. [ABSTRACT FROM AUTHOR]

Background: Ankylosing spondylitis (AS) is an inflammatory autoimmune disease that mostly affects different joints of the body. Macrophages are the predominant cells that mediate disease progression by secreting several pro-inflammatory mediators. Different receptors are involved in macrophages' function including the adenosine receptors (AR). Our main objective in this study was to assess the effect of applying A2A adenosine receptor agonist (CGS-21,680) on the gene expression of inflammatory mediators including bone morphogenetic proteins (BMP)-2, 4 and matrix metalloproteinases (MMP)-3, 8, 9, and 13 on the macrophages from AS patients compared to healthy macrophages.Methods: Monocytes were isolated from the whole blood of 28 individuals (AS patients and healthy controls in a 1:1 ratio). Macrophages were differentiated using macrophage colony-stimulating factor (M-CSF), and flow cytometry was performed to confirm surface markers. CGS-21,680 was used to treat cells that had been differentiated. Using SYBR green real-time PCR, relative gene expression was determined.Results: Activating A2AAR diminished MMP8 expression in healthy macrophages while it cannot reduce MMP8 expression in patients' macrophages. The effect of A2AAR activation on the expression of BMP2 and MMP9 reached statistical significance neither in healthy macrophages nor in the patients' group. We also discovered a significant positive connection between MMP8 expression and patient scores on the Bath ankylosing spondylitis functional index (BASFI).Conclusion: Due to the disability of A2AAR activation in the reduction of MMP8 expression in patients' macrophages and the correlation of MMP8 expression with BASFI index in patients, these results represent defects and dysregulations in the related signaling pathway in patients' macrophages. [ABSTRACT FROM AUTHOR]

• New hydroxylammonium - based ILs. • Structure confirmed by FTIR and 1D NMR spectroscopy. • Correlation between chemical structure and ion conductivity. In the research work, new protic ionic liquids (Pr - ILs) were synthesized by an acid - base neutralization reaction. The influence of IL chemical structure (i.e. anion and cation nature) on the thermal behavior, viscosity and ionic conductivity was evaluated. To confirm the chemical structure of synthesized Pr - ILs, nuclear magnetic resonance (1H and 19F) and Fourier transform infrared spectroscopy analyses were performed. Thermal analysis demonstrated that the influence of anion nature on the IL thermal stability was more pronounced than that of cation. The ionic liquids with trifluoromethanesulfonate anion showed the highest thermal stability (T deg ∼ 410–420 °C) as compared with other studied anions (i.e. phosphate and acetate anions). The trifluoromethanesulfonate - based Pr - ILs also demonstrated high ionic conductivity – between ∼58 and ∼64 mS·cm−1 at 150 °C and non - humid conditions. Despite the fact that phosphate - based Pr - ILs were more thermally stable (T deg ∼ 250–280 °C) than acetate - based ones (T deg ∼ 215 °C), acetate - based Pr - ILs revealed a higher ionic conductivity (∼15–19 mS·cm−1 at 80 °C) than phosphate - based Pr - ILs (∼0.2–1 and ∼0.4–2 mS·cm−1 at 80 and 120 °C, respectively). The obtained results confirm that the synthesized Pr - ILs are promising candidates for using them in electrochemical applications, namely, electrodialysis and fuel cells. [ABSTRACT FROM AUTHOR]

The effectiveness of inactivated H9N2 influenza vaccines is doubtful due to changes in antigenic regions of the virus hemagglutinin (HA) protein. One strategy for the development of the efficacious vaccine is the use of nanoparticles that display more immunogenic regions of the influenza virus. In this study, chitosan (CS)-based nanoparticles were developed as a delivery system for intranasal immunization using recombinant H9N2 virus HA1 and nucleoprotein (NP), for the induction of humoral and cellular responses. CS-HA1 and CS-NP nanoparticles were prepared by the ionic gelation method and characterized for their physicochemical properties and shape. The immunogenicity and the protective efficacy were evaluated by measuring antibody titers, T cell proliferation response, CD4+/CD8+ ratio, and quantitative real-time RT-PCR following intranasal administration of the prepared nanoparticles alone or in combination in chickens compared to an inactivated H9N2 vaccine. The average size, surface charge, and spherical structure of the synthesized nanoparticles showed high quality. Serologic analysis revealed that the immunization of inactivated vaccine groups resulted in strong influenza antibodies, which were significantly (p < 0.05) higher compared to the other groups. The vaccinated chickens with CS-HA1+CS-NP developed higher specific anti-influenza antibodies than in those vaccinated with each of rHA1 and rNP. Administration of a combination of the protein-based nanoparticles has stimulated the activation of both CD4+ and CD8+T cells and induced a significantly higher T cell proliferation. The viral shedding was significantly lower in CS-HA1+CS-NP and inactivated vaccine groups compared with other challenged groups. The data demonstrate the potential of CS-HA1+CS-NP nanoparticles for eliciting specific influenza antibodies and conferring protection in chickens. [ABSTRACT FROM AUTHOR]

Achieving sustainable development is one of the most important agricultural resources. Therefore, the overall purpose of this study is to investigate the factors affecting farmers' desire to change the cultivation pattern to cultivation of medicinal plants. The research method is allowed as a field-library. After determining the variables through questionnaires and software SPSS. The statistical population of this study is rural producers in Targabah district in Khorasan Razavi Province in Iran. The statistical sample for this study was 204 rural households. The sample was calculated using random sampling based on Cochran formula. The results show that the farmers' desire to change the cultivation pattern to cultivation of medicinal plants has a significant positive correlation with its level of economic, social, technical and environmental awareness. Also, it has a significant and positive relationship with his understanding of the production of medicinal plants which can enhance the protection of the environment. The results of the diagnostic analysis showed that the level of economic awareness and awareness of processing plants and product packaging can affect the farmers' desire to change the cultivation pattern to cultivation of medicinal plants. [ABSTRACT FROM AUTHOR]

Introduction: The virulent Newcastle disease virus (NDV) strains cause an economically important infectious disease in poultry. The common vaccination program with genotype II NDV strains is routinely practiced to provide a better protection level against Newcastle disease (ND). Nevertheless, the emergence of new antigenic and genetic variants within the circulating NDVs raises the importance of improved control strategies. The genotype VII NDV is associated with many of the most recent outbreaks of the disease worldwide. Methods: We evaluated the impacts of genetic divergence between the genotypes II and VII on the immunity against NDV to choose a suitable vaccine virus candidate by focusing on the F and HN proteins. Comparative bioinformatics analyses based on B- and T-cell epitopes binding affinity, protein secondary structure and physicochemical properties predictions were applied for genotypes II and VII. Results: Although the results showed more differences in HN protein than F protein, there was no major difference between the predicted antigenicity values, epitope regions, affinity binding to MHC-I and MHC-II, secondary structures, surface accessibility, and stability of these immunogens between genotypes II and VII. Conclusion: The results suggest that genotype II-based live vaccines can induce immune responses against NDV; however, an inactivated vaccine formulated by genotype VII should be considered in combination with the traditional live vaccine to provide better protection in controlling programs against ND. [ABSTRACT FROM AUTHOR]

Background: The present study was conducted to investigate the relationship between metabolic syndrome and the risk of respiratory and sleep disorders in professional drivers. Methods: This case-control study was conducted on professional drivers in Shahroud, Iran. The snoring, tiredness during daytime, observed apnea, high blood pressure, body mass index, age, neck circumference, gender (STOP-Bang) questionnaire was first used to assess obstructive sleep apnea (OSA). Then, based on the questionnaire scores, the participants were divided into two groups: those with and those without OSA. The relationship between this disorder and metabolic syndrome was then studied. Data were analyzed using descriptive and analytical tests (P<0.05). Results: Based on the STOP-Bang questionnaire, 214 drivers with a high risk of OSA and 214 drivers with low risk were recruited for the study. According to the Adult Treatment Panel III criteria, 204 drivers (47.7%) had metabolic syndrome. There was a significant relationship between driver's license class and the risk of OSA. Metabolic syndrome components including fasting blood sugar, triglycerides, and hypertension, but not high-density lipoprotein cholesterol, were able to predict OSA in the professional drivers. Conclusion: Given the high prevalence of metabolic syndrome and OSA, especially in drivers of high risk who may spend long hours transporting good and operating passenger vehicles, screening and treating these disorders are crucial in this part of the population. The researchers recommend holding regular training sessions about these disorders for professional drivers. [ABSTRACT FROM AUTHOR]

Steer-by-wire (SBW) systems benefit from several advantages including lower weight, volume, and cost compared to counterpart electric power steering systems. However, system reliability is impacted since SBW performance is highly dependent on correct operation of several voltage, current, speed, yaw rate, and position sensors. This paper presents a new method in SBW system reliability improvement by introducing a novel fault detection, isolation, and reconstruction (FDIR) control technique. The proposed FDIR method detects if any fault is observed on voltage or current sensors and identifies the faulty sensor location. Additionally the identified faulty sensor's output is replaced with an estimated value to allow system continuous fault-ride through operation. The SBW system equipped with proposed FDIR technique provides fault-tolerance property against up to 3 faulty voltage or current sensors. Therefore, enhanced overall reliability is obtained at no further hardware costs associated with additional sensors redundancy solutions. The proposed technique is studied using system modelling and hardware prototyping, and its effectiveness is demonstrated using simulation and experimental results. [ABSTRACT FROM AUTHOR]

[Display omitted] • This study proposes novel auxetic medical stents. • Two-dimensional metamaterials were fabricated through additive manufacturing technique. • Finite element analysis was employed to investigate the mechanical behaviour. • An excellent correlation was observed between the FEA and experimental results. • The modifications made to the rib-unit cells had a significant effect on the stent's recoil behaviour. Due to the significant mortality rate associated with atherosclerosis-induced cardiovascular disease, the utilization of advanced intravascular stents with superior mechanical performance is imperative for the restoration of obstructed arteries. This study proposes novel auxetic medical stents that aim to enhance critical parameters of biomedical stents. This includes load-bearing capacity, expanded opening percentage, and reduced recoil percentage. On this matter, the missing rib auxetic unit cell has been considered and geometrically modified to achieve these objectives. Two-dimensional (2D) metamaterials were fabricated through additive manufacturing technique and subjected to experimental testing. Then, finite element analysis (FEA) was employed to gain comprehensive insights into the mechanical behaviour of the proposed medical stents. Remarkably, an excellent correlation was observed between the FEA and experimental results, validating the high precision of the analysis. The findings reveal that the stents classified as "E-category" exhibit the highest final opening percentage while concurrently demonstrating the lowest recoil percentage. The base stent exhibited a relatively high recoil percentage of 15.56%, indicating a significant amount of recoil or spring-back after deformation. In contrast, the modified "E-category" stent displayed a substantially lower recoil percentage of 1.62%. This notable reduction in recoil percentage indicates that the modifications made to the rib-unit cells had a significant and beneficial effect on the stent's recoil behaviour and minimizing potential damage to arterial tissue during stent deployment (angioplasty) and balloon pressure. The modified design likely enhances the stent's ability to maintain its shape and resist recoil, making it more effective and reliable in its intended application. Additionally, more aspects of biomedical stents such as foreshortening, and dog-boning of the modified missing rib stents were meticulously examined through FEA. [ABSTRACT FROM AUTHOR]

Background: Non-ionic surfactant, Tween-80 (TW80) is commonly used for drug delivery due to its effect on the cell membrane permeation. The change in permeability can also increase viral infectivity in cells. This study was undertaken to improve upon Newcastle disease virus (NDV) titer cultivated with embryonic chicken eggs. Methods: The toxicity of TW80 was investigated against chicken embryos at varying concentrations, and changes in the morphology and weights of the heart, liver, and spleen of 4-day old chicken embryos were analyzed. Also, the effect of non-toxic concentrations of TW80 was examined on the infectivity of NDV. The virus was titrated in the allantoic fluid, using a 50% embryo infectious dose (EID50). Results: At high concentrations of TW80, hemorrhage-induced mortality was observed in embryos at the early stages of incubation. The embryos' viability was not affected at low TW80 concentrations, indicating that its toxicity to the chicken embryos was dose-dependent. The infectivity titer of NDV was increased in the presence of TW80 compared to those inoculated with NDV only. Conclusion: The data suggest that TW80 is toxic to chicken embryos at high concentrations, but it enhances cell membrane permeability for NDV particles at low concentrations without affecting the embryos' viability. [ABSTRACT FROM AUTHOR]

This article proposes a methodology for critical path selection and delay sensor insertion for aging monitoring in field-programmable gate arrays (FPGAs). The aging information can be used to reconfigure FPGAs to achieve better performance or wear leveling. To filter out the paths aging less aggressively, our methodology decides based on both physical-level parameters [e.g., path delay, process variation, temperature, static stress (duty cycle), and dynamic stress (switching activity) as well as aging-relevant parameters (e.g., fan-out, and endpoint physical location)]. After selection of an optimal set of paths, age sensors, introduced in our earlier work, are placed in a distributed fashion throughout the FPGA area to provide aging information of its various parts as they are being used. Accurate aging models for FPGAs are required to determine the contribution of the above-mentioned parameters in aging. In this article, ASICs’ aging models are adapted for FPGAs through measurement-based fitting approach. The experimental results using various benchmarks reveal that our algorithm selects paths with a minimum error. [ABSTRACT FROM AUTHOR]

In this article, we propose a fine-grained FPGA aging mitigation method. Our method focuses on Look Up Tables (LUTs) on which Boolean functions are mapped. Based on our observations, for any configuration, even if it is carefully selected, a number of LUT transistors experience severe stress rates. Therefore, an algorithm is presented to select several alternative configurations for each LUT. Alternative configurations are obtained by LUT input reordering. These alternative configurations are rotationally loaded into the FPGA. Experimental results shows that our method achieves 263 and 14.1 percent Mean Time To Failure (MTTF) improvement for Hot Carrier Injection (HCI) and Bias Temperature Instability (BTI), respectively. Additionally, due to changing only local routings, our method imposes up to 1 percent performance overhead to the systems. [ABSTRACT FROM AUTHOR]

In the recent years chemical control of weeds has become a dominant method of weed control. The heavy use of these chemicals has had a negative impact on the environment and human health. So this study tries to investigate the analysis paddy farmers' knowledge about integrated weed management (IWM) in Iran. The study was done by a descriptive-surveying method that including field and documentary data. The population of the study consisted of selected Dooreh - CHegeni farmers that cultivation wheat and rice together. Sample population was selected by using the Cochran formula (n=198). The main instrument used in this study was a questionnaire. The validity of research tool was obtained by the idea of experts and for reliability of questionnaires a pilot test was conducted. The Cronbach' Alpha coefficient of higher than 0.7 showed that research tool was reliable (learning style (0.818), economic characteristic (0.700) and social characteristic (0.723) respectively). The result of correlation analysis showed that the variables such as: belief in discussion with other farmers about sustainable weed management, the importance of dialogue and implement the recommendations of experts, quality and quantity of extension programs, attitude towards the impact of SWM (Sustainable Weed Management) on healthy crop production and farmers 'attitude toward the effects of this type of management on increasing production has a significant effect on farmers' awareness of integrated weed management in the field The results also showed that farmers' use of appropriate seed (weed-free) and farmers' appropriate attitude toward discussion with other farmers about integrated weed management in the field is the most important variable could be predicted the rice farmers' knowledge of IWM(Integrated Weed Management) in the field. [ABSTRACT FROM AUTHOR]

This paper introduces a groundbreaking approach to demand response management, aiming to empower consumers through innovative strategies. The key contribution is the concept of "acquiring flexibility rights", wherein consumers engage with power aggregators to curtail energy usage during peak-load periods, receiving incentives in return. A flexibility right coefficient is introduced, allowing consumers to tailor their participation in demand response programs, ensuring their well-being. Additionally, a lighting intensity control system is developed to enhance residential lighting network efficiency. The study demonstrates that high-energy consumers, adopting a satisfaction factor of 10, can achieve over 61% in electricity cost savings by combining the lighting control system and active participation in demand response programs. This not only reduces expenses but also generates income through the sale of flexibility rights. Conversely, low-energy consumers can fully offset their expenses and accumulate over USD 33 in earnings through the installation of solar panels. This paper formulates an optimization problem considering flexibility rights, lighting control, and time-of-use tariff rates. An algorithm is proposed for a distributed solution, and a sensitivity analysis is conducted for evaluation. The proposed method showcases significant benefits, including cost savings and income generation for consumers, while contributing to grid stability and reduced blackout occurrences. Real data from a residential district in Tehran validates the method's effectiveness. This study concludes that this approach holds promise for demand response management in smart grids, emphasizing the importance of consumer empowerment and sustainable energy practices. [ABSTRACT FROM AUTHOR]

Sparse linear arrays (SLAs) provide a high number of degrees of freedom (DOF) and reduce the mutual coupling effect between sensors of the array. Many design methods for SLAs have been proposed in the last two decades but most of the existing SLA design methods fail to achieve minimum number of sensors for a desired DOF. In this paper, a design method is proposed which utilizes the branch and bound (B & B) optimization algorithm to give a SLA with the desired DOF and minimum number of physical sensors. The proposed SLA design method is obtained by generalizing the minimum sensor array (MSA) design method which is recently proposed in the literature. This generalized method provides the same DOF as the MSA method but with a smaller number of physical sensors. In addition, a version of this design method is proposed which provides more robustness against mutual coupling effect between the sensors of the array. Simulation results demonstrate the superiority of the performance of the SLAs obtained with the proposed method over the arrays obtained with the MSA method and also over the other existing SLAs. [ABSTRACT FROM AUTHOR]

[Display omitted] • A novel CNN model was developed for predicting soil texture based on fusing NIR and image data. • Data sizes, NIR pre-processing methods, and image types were optimized. • HSV images and NIR spectra preprocessed with derivation boost CNN performance. • Multi-dimensional CNN accurately predicts clay and silt fractions. • Fused model achieves high prediction accuracy with smaller dataset. Soil texture is very important information for various agricultural, environmental, and geological research areas, however, it has been difficult to obtain data through proximal sensing due to the lack of appropriate predictive models. In this study, sand, silt, and clay contents of soil samples were evaluated using fusion data with the near-infrared (NIR) and image based on the convolutional neural network (CNN) model. For the development of the applicable predictive model, the preprocessing methods such as standard normal variate (SNV) and derivative, image types and size were optimized, and the performance of the CNN model was enhanced using only a small amount of data (n = 250). As results, the SNV and derivative methods increased model performance (R2 > 0.91) for the NIR dataset, and the red–green–blue (RGB) and hue-saturation-value (HSV) image types showed high performance (R2 > 0.84). Meanwhile, the fusion dataset improved the model performance than the individual dataset. The model performance (R2) could be achieved over 0.93 using fusion data of size 30 × 30 regardless of soil fraction. Furthermore, this trained model showed better predictive performance (R2) than the previous models even on the test dataset: 0.69 and 0.80 for silt and clay, respectively. Therefore, these results demonstrated that the proposed CNN model using NIR and image fusion data showed the potential to accurately predict silt and clay fractions despite the small amount of training data. [ABSTRACT FROM AUTHOR]

Electronic properties of (n,0) zigzag tungsten disulfide WS 2 nanotubes and transport properties of (7,0) zigzag nanotube heterojunction are investigated by utilizing non-equilibrium Green's function formalism (NEGF). The results reveal that inclusion of the spin-orbit (SO) coupling significantly reduces the value of the band gap about 15.52\%. Additionally, strong negative differential resistances take place in voltage regions between −0.2 and −0.4 V as well as between −0.5 and −0.6 V. Moreover, temperature dependent transport properties are elaborately investigated in this work. The results show that, as the temperature increases to 600 K the stronger negative differential resistance occurs in both positive and negative bias voltages. Finally, a reasonably large degree of rectification ratio can be established. Our analysis can provide a comprehensive perspective on the NDR effect and current rectification in WS 2 nanotubes and can be used as a beneficial guide for future designing of novel logical and nanoelectronic and spintronic devices. • All electronic calculations were carried out using ab-initio DFT-NEGF method. • Transport characteristics were discussed with and without SO coupling. • Reduction of band gap and strong NDR were obtained in the percent of SO coupling. • Stronger NDR was occurred by temperature increasing. [ABSTRACT FROM AUTHOR]

Despite the robust induction of humoral immune responses, a limitation of many adjuvants is their weak stimulation of cellular immunity. The development of synthetic gene-encoding adjuvants for simultaneous induction of both humoral and cell-mediated immune responses is under study. In this study, we examined the impact of toll/interleukin-1 receptor (TIR) domain of toll-like receptor 7 (TLR7) as molecular adjuvants on potency of inactivated infectious bursal disease (IBD) vaccines. A total of 60 specific pathogen-free week-old chicks were randomized grouped to receive either TIR-TLR7-adjuvanted IBD-inactivated vaccine or inactivated IBD antigen along with an unvaccinated control. Serum antibody titers were measured to estimate the humoral immunity, as well as lymphocyte proliferation activity for cellular immune responses. The protection was estimated after challenge with a very virulent IBD virus (IBDV) strain at 4 weeks postvaccination. The results indicated that one dose of IBD/TIR-TLR7 vaccine induced specific antibody responses, whereas a lower response after administration of inactivated IBD antigen was observed. The stimulation of splenocytes results indicated that the TIR-TLR7 adjuvanted IBD vaccine is capable of modulating cell-mediated immune response in treated chickens. A full protection against IBDV infection was achieved by injection of one dose IBD/TIR-TLR7 vaccine in the challenge trial. This study demonstrated that codelivery of TIR-TLR7 with inactivated IBD antigen resulted in simultaneous enhancing immune responses against IBD. [ABSTRACT FROM AUTHOR]

In this paper, new steady-state analysis is proposed for a series resonant converter (SRC) that provides closed-form expressions for converter waveforms. Using the proposed analysis, explicit equations are obtained to design the converter components. It is shown that an SRC can be modeled through a nonlinear differential equation with discontinuous inputs. A Laplace-based theorem (LBT) is provided to obtain the steady-state analytic solution of the resonant converter differential equations. Using the LBT, a flowchart is proposed to analyze the converter where the nonlinearity of differential equation is removed by defining intermediate variables. The variable duty ratio SRC is analyzed using the proposed flowchart. Accurate, closed-form, and explicit equations for converter waveforms, voltage gain, current phase lag, zero voltage switching, and discontinuous conduction mode boundaries are derived. The proposed analysis is compared with conventional methods and its accuracy is validated through simulations and experimental results. Moreover, using the proposed method, a novel procedure is provided for the optimal design of the converter and is compared with conventional design approaches. [ABSTRACT FROM AUTHOR]

Aim: To investigate the relation between the circadian rhythm amplitude and stability, and occupational stress with burnout syndrome and job dissatisfaction among shift working nurses. Background: Irregular shift working nurses are prone to burnout syndrome (BS) and job dissatisfaction (JD). circadian rhythm difference and occupational stress might be effective in causing burnout syndrome and dissatisfaction. Design: In total, 684 nurses who worked in four teaching hospitals were selected by stratified random sampling in a cross‐sectional design based on STROBE guidelines. Methods: The data were collected by the Circadian Type Inventory, Job Content Questionnaire, Minnesota Satisfaction Questionnaire and the Maslach Burnout Inventory. Multiple linear regression, one‐way ANOVA and independent t test were used for statistical analysis by SPSS v24. Results: About 15% of the nurses suffered from high levels of burnout syndrome. Psychological demand (β = 0.022, CI 95% = 0.003‒0.047 and β = 0.016, CI 95% = 0.001‒0.032) and workplace support (β = −0.043, CI 95% = −0.097–0.003 and β = −0.025, CI 95% = −0.046–0.006) were significant predictors of BS and JD. Male nurses reported lower BS and higher JD compared to female nurses. Irregular shift working schedule was also related to a significantly higher odd of BS (p = 0.009) and JD (p = 0.011). Nurses classified as languid experienced significantly more BS and JD than vigorous nurses. Conclusion: This study shows that BS and JD were strongly associated with psychological demand and workplace support; and vigorous nurses were less prone to BS and JD, and were more suitable for irregular shift work. Relevance to clinical practice: In order to reduce burnout syndrome and job dissatisfaction among irregular shift working nurses, we need to identify the effect of risk factors such as individual differences on the circadian rhythm and job demand which can affect nurses who work in irregular schedules. [ABSTRACT FROM AUTHOR]

Highlights • Day-ahead microgrid scheduling is modeled in this paper. • The uncertainties are modeled by robust optimization with recourse approach. • Test results of the proposed method on 69 bus distribution system are presented. • Superiority of the proposed method compared with deterministic method is shown. Abstract This paper proposes a framework to address day-ahead scheduling of a microgrid (MG) with wind, solar and micro-turbine distributed generators as well as batteries, considering the associated uncertainties and AC power flow constraints. The problem uncertainties are wind and solar generations, demand, and grid electricity price. The uncertainties are modelled using bounded intervals within adaptive robust optimization method. Unlike previous robust models presented for MG scheduling, our proposed adaptive robust model optimizes both wait-and-see and here-and-now decisions simultaneously which leads to obtaining a better operating point. In order to make wait-and-see and here-and-now decisions and immunize the model against worst case realizations, the proposed MG scheduling model has been formulated as a tri-level optimization framework. In the first level, here-and-now commitment decisions are made (these are decisions made before realization of uncertainties). In the second stage, the worst case realization of the uncertain parameters is determined. In the third level, the wait-and-see recourse decisions are made (these are decisions made after realization of uncertainties). Since there are before uncertainty-realization decisions, worst uncertainty-realization determination, and after uncertainty-realization decisions, the proposed model becomes a tri-level optimization framework. The proposed adaptive robust tri-level MG scheduling model, the proposed solution approach including AdptRob and ConvAC problems, and the proposed out-of-sample analysis are the main contributions of this paper. A convexified AC power flow model is used in the proposed framework for modeling the distribution network. The 69-bus distribution test system is used to test the proposed adaptive robust model as well as the proposed solution approach which converges very fast. Moreover, the results of the out-of-sample analysis shows that the proposed adaptive robust model results in lower expected cost and lower cost variance. [ABSTRACT FROM AUTHOR]

This paper defines the concept of ideal entropy for BCI-algebras in general, and it tries to describe some of its properties. Moreover, the present study will show that F2n (i.e., sets of every binary code word of length n) is a BCI-algebra, and that each ideal of F2n is a linear code. The present study defines the concept of cosets by using the quotient BCI-algebra F2nI and obtains their properties. This study defines the complement of a linear code, which is itself a linear code, which is denoted by the symbol Cc. Further, the present study defines the standard complement of a linear code, which is unique. This study proves that each equivalence class in F2n/Cc contains one and only one code word of the linear code C. This property can be used for decoding. Finally, the present study shows that two linear codes are equivalent if and only if they have the same ideal entropy. [ABSTRACT FROM AUTHOR]

Huntington disease (HD) is an inherited disorder hallmarked by progressive deterioration of specific neurons, followed by movement and cognitive anomalies. Cell therapy approaches in neurodegenerative conditions have concentrated on the replenishment of lost/dying neurons with functional ones. Multipotent mesenchymal stem cells (MSCs) have been represented as a potential remedy for HD. In this study, we evaluated the in vitro and in vivo efficacy of umbilical cord matrix stem cells (UCMSCs) and their paracrine effect against oxidative stress with a specific focus on HD. To this end, UCMSCs were isolated, immunophenotypically characterized by the positive expression of MSC markers, and exhibited multilineage potentiality. Besides, synthesis of neurotrophic factors of GDNF and VEGF by UCMSC was confirmed. Initially, PC12 cells were exposed to superoxide in the presence of conditioned media (CM) collected from UCMSC (UCMSC-CM) and cell viability plus neuritogenesis were measured. Next, bilateral striatal transplantation of UCMSC in 3-nitropropionic acid (3-NP) lesioned rat models was conducted, and 1 month later, post-graft analysis was performed. According to our in vitro results, CM of UCMSC protected PC12 cells against oxidative stress and considerably enhanced cell viability and neurite outgrowth. On the other hand, transplanted UCMSC survived, decreased gliosis, and ameliorated motor coordination and muscle activity, along with an increase in striatal volume as well as in dendritic length of the striatum in HD rats. Collectively, our findings imply that UCMSCs provide an enriched platform by largely their paracrine factors, which downgrades the unfavorable effects of oxidative stress. [ABSTRACT FROM AUTHOR]

One of the most important dimensions of cooperative systems, which have existed in Iran since 1974, is cooperative rural production enterprises. In this study, the performance of rural production cooperatives in Iran is examined in relation to the social capital components of the members. This study's statistical population consisted of 16,870 members from 41 cooperatives. 217 samples of cooperative members and 98 samples of the cooperative's management and board of directors were selected using the Cochran formula, and questionnaires were filled out for each group. The results showed that from the viewpoint of the members of rural cooperatives, the most important factor in improving the performance of cooperatives was the use of effective extension training (model-extension sites). The results also showed that members' satisfaction and training members of cooperatives can play an important role in improving the performance of cooperatives. The results of this research, while emphasizing the role of education (especially extension activities), can help rural development planners in improving the performance of rural cooperatives in their regions. [Display omitted] • The study identified the impacts of social capitals on the performance of rural production cooperatives. • The most important factor in improving the performance was the use the extension trainings. • Members' satisfaction and training play an important role in improving the performance. • The level of education in production cooperatives has a direct relationship with trust and satisfaction. • Cooperatives do not perform well in the fields of sales, marketing and insurance. [ABSTRACT FROM AUTHOR]

Initial low cost of pesticides and lack of knowledge on the part of agricultural producers has led to an overuse of pesticides, with dangerous consequences. On the other hand, today, pesticides have an important role in the increment of agriculture products. Therefore, in recent years, the major aims of agricultural, environmental and even the food industry researchers have been to reduce the usage of chemical materials in agricultural applications. To achieve this, variable rate application in sprayers using different technologies such as machine vision, ultrasonic sensors, spectrometry, laser scanning, as well as pest identification and classification, have been applied in recent studies. This paper reviews these works reported in the 21 century. In addition, the best result is suggested in the conclusion section for future studies. [ABSTRACT FROM AUTHOR]

This study was conducted to investigate ocular complications and their relationship with sleep problems between IT students at Shahroud University of Technology as professional computer users and public health students at Shahroud University of Medical Sciences as non-professional computer users. This descriptive, cross-sectional study was conducted in 2014-2015 on 290 students, including 145 IT and 145 public health students. The students were selected by simple random sampling. Data were collected using five questionnaires, including a demographic questionnaire, the Ocular Surface Disease Index (OSDI), the Visual Fatigue Questionnaire, the Epworth Sleepiness Scale (ESS) and the STOP-BANG, and an examination for visual acuity. Data were analyzed in SPSS-22 using descriptive and inferential statistics and the level of statistical significance was set at P < 0.05. The comparisons showed a significant difference in the mean scores of the OSDI, VFQ and ESS between the male and female students, as all these scores were higher in the female students; however, no significant differences were observed in these scores between the professional and non-professional users. Given the significant direct relationships between the scores of the four questionnaires, it can be argued that sleep disorders and ocular disorders have reciprocal effects on each other. Sleepiness, dry eye and eye strain were not different between the groups of professional and non-professional computer users, but long hours of computer and cellphone use were observed so all students need to receive further education and correct ergonomics regardless of their field of study. [ABSTRACT FROM AUTHOR]

Currently, a variety of immunostimulatory molecules are used as adjuvants in combination with poor immunogenic recombinant infectious bursal disease virus (IBDV) vaccine antigen. TIR domain of Toll-like receptors (TLRs) triggers the interleukin-1 (IL-1) signaling cascade which plays a critical role in immune responses against infectious agents. For this study, the bacmid DNA pBac-VP2 of a field isolate was generated and transfected to Sf9 insect cells to produce recombinant VP2 (rVP2). In addition, based on in silico analysis, the cDNA encoding the conserved TIR domain of TLR7 (TIR-TLR7) contain the IL-1 receptor was synthesized and used as an adjuvant. We further evaluated the ability of rVP2/TIR-TLR7 vaccine candidate to induce specific immune responses in specific pathogen-free (SPF) chickens and compared the efficacy by challenging with the virulent IBDV. The results indicate that rVP2/TIR-TLR7-adjuvanted vaccine elicited humoral immune responses and protected chickens against IBDV infection. Higher levels of neutralizing IBDV antibody titers were observed in chickens intramuscularly immunized with rVP2/TIR-TLR7 than those injected with rVP2 alone. The antibody titers were higher in chickens which received booster injection. Furthermore, chickens immunized with rVP2/TIR-TLR7 in the prime and boost groups had significant protection against a virus challenge. The survival rate was 70 and 90% after the primary and booster rVP2/TIR-TLR7 vaccinations, respectively, and indicated that they were protected from virus challenge. Despite the unvaccinated control group, the immunized chickens with rVP2/TIR-TLR7 did not show any clinical signs and histopathological changes of the bursa. Our results demonstrate that TIR-TLR7 is a potential vaccine adjuvant and can induce antigen-specific immune responses induced by rVP2 for protection against IBDV infection. [ABSTRACT FROM AUTHOR]

Geolocated social media data provide a powerful source of information about places and regional human behavior. Because only a small amount of social media data have been geolocation‐annotated, inference techniques play a substantial role to increase the volume of annotated data. Conventional research in this area has been based on the text content of posts from a given user or the social network of the user, with some recent crossovers between the text‐ and network‐based approaches. This paper proposes a novel approach to categorize highly‐mentioned users (celebrities) into Local and Global types, and consequently use Local celebrities as location indicators. A label propagation algorithm is then used over the refined social network for geolocation inference. Finally, we propose a hybrid approach by merging a text‐based method as a back‐off strategy into our network‐based approach. Empirical experiments over three standard Twitter benchmark data sets demonstrate that our approach outperforms state‐of‐the‐art user geolocation methods. [ABSTRACT FROM AUTHOR]

Constraints on resources, staff, facilities, and other features of the multidimensional problems of the cultivation, production, trafficking, and use of illicit drugs (or drugrelated activities) in Afghanistan require many organizations to work together. The advantages of this cooperation include effectively and efficiently combating this multidimensional phenomenon. Addressing this, this paper examines the patternized interactions among counternarcotics stakeholders in the collaborative process of combating drugs in Afghanistan based on a typology of network governance: shared governance network, lead organization-governed network, and network administrative organization. This study reveals that counternarcotics policies are implemented in vast networks including governmental, nongovernmental and international actors in the form of multilevel and multisectoral governance across seven types of counternarcotics activities, comprising influence in decision making, information and advice seeking, collaboration, resource sharing, funding provision, and goal congruence. This research also improves our understanding of network governance, in which counternarcotics stakeholders are actually collaborating within several distinct networks across different areas of counternarcotics activities in Afghanistan. [ABSTRACT FROM AUTHOR]

This paper is devoted to introduce and study Rényi and Tsallis entropy, conditional Tsallis entropy and Tsallis mutual information of D-posets on a state s. Several relations between the conditional entropies are derived. Finally we define Tsallis entropy of dynamical system on D-posets and a new version of Kolmogorove-Sinai Theorem has been proved. [ABSTRACT FROM AUTHOR]

The monoid Cb of name substitutions originated by Pitts in name abstraction, and the notion of a finitely supported Cb-set appeared in the study of models of homotopy type theory in the works of Gabbay and Pitts. On the other hand, retracts and retractions play a crucial role in most branches of mathematics as well as in computer science where partial morphisms need to be completed. Retracts are the subobjects whose related inclusion morphism have a left inverse, called retraction. In this paper, we study the retracts and retractions of cyclic finitely supported Cb-sets. We find the general definition of retractions from a cyclic Cb-set, and give necessary conditions under which retractions exist. Also, fix-simple retracts of a cyclic Cb-set are characterized. Further, the cyclic finitely supported Cb-sets all whose subobjects are retract, are studied. In particular, we give a necessary condition for a cyclic finitely supported Cb-set to be retractable. [ABSTRACT FROM AUTHOR]

Introduction Work-related stress and its causes are among the most important issues which can seriously challenge organizational efficiency and employees' health. Different occupational environments and groups have different levels of job stress. The present study aimed to investigate relationships between job stress and its dimensions with three occupational groups (administrative, administrative-operational, and operational) among a subsidiary company workers of Iranian Oil Refining and Distribution Company. Methods The present study had descriptive-analytical and cross-sectional type and was conducted among 468 out of 503 employees (with entry condition of a year of work experience as well as an official and contractual membership) volunteered to participate in research. Data collection tools included demographic questions and job stress questionnaire as well as human resource department information to determine occupational group of employees. Descriptive statistics, statistical tests, Independent test, and oneway ANOVA in addition to SPSS 21 software were used for data analysis. Results There were significant relationships between age, education levels, work experience and smoking with mean score of job stress (P-value <0.05). Mean score of employees' job stress in operational occupation group was significantly higher than other two occupational groups (P-value=0.004), and there were significant relationships between employees' occupational group variables with five dimensions of job stress (demand, relationships and role, managerial support, and peer support) (P-value<0.05). There were not any significant relationships between other variables and job stress (Pvalue> 0.05). Conclusions Exposure to different occupational harmful agents, facing with different safety risks, being far from family, heavy workload, and uncertain employee roles have significantly increased job stress in both operational and executive occupation groups compared to other two occupational groups; hence, there is a positive correlation between high job stress and operational jobs. [ABSTRACT FROM AUTHOR]

This paper presents an instantaneous torque control method for cascaded doubly fed induction machines (CDFIMs) with a rated torque-sharing ratio feature under steady-state operation. A CDFIM includes two coupled main and auxiliary doubly fed induction machines, and the rated torque-sharing ratio herein means that the machine torques are proportional to the machine ratings. The proposed method is established based on transferring the torque equations of the two machines into the rotor-flux reference frame of the auxiliary machine. Then, the instantaneous torque and the rated torque-sharing ratio are controlled via the stator current components of the auxiliary machine, while machine fluxes are within allowable ranges. To verify the method and evaluate its capabilities, the suggested method is used for the speed control of a CDFIM experimental setup including two 4-kW doubly fed induction machines and a 4-kW dc machine to apply a sudden mechanical load change to the CDFIM. Further, a case study including 12-kW and 4-kW DFIMs is also simulated to evaluate the performance of the torque control method for a CDFIM with different machine ratings. The test results confirm that the proposed control schemes achieve the desired performances without exceeding the ratings of the machines under various test scenarios. [ABSTRACT FROM AUTHOR]

This paper proposes a linear and efficient transmitter prototype based on pulsed load modulation (PLM) power amplifier (PA). The proposed transmitter setup utilizes the complex delta–sigma (DS) modulation as a signal processing technique instead of the envelope DS modulation for higher linearity performance. Using the complex DS modulation technique reduces the in-band quantization noise significantly at the output of the modulator and consequently, enhances the linearity of the transmitter. To validate the proposed technique, the linearity and efficiency performance of the complex DS modulator (CDSM)-based transmitter are compared with the performance of its envelope DS modulator (EDSM) counterpart in measurement. For this paper, an efficient and linear PLM PA is designed and fabricated using GaAs E-pHEMT transistors. For a Long-Term Evolution (LTE) uplink standard signal with 3-MHz bandwidth and 7-dB peak-to-average power ratio, the CDSM-based transmitter achieves the drain efficiency and power added efficiency of 46% and 42%, respectively, at an average output power of 25.1 dBm. The comparison measurement study of EDSM-based transmitter and the CDSM-based transmitter with the LTE uplink signal shows about 11-dB improvement in the signal-to-noise and distortion ratio of the output signal. The measurement results for LTE signals were able to pass the spectral requirements defined by the standard without applying predistortion techniques. [ABSTRACT FROM AUTHOR]

We used a reflected shock tube to investigate the acoustic signature of a hot jet at the far-field. Experiments were performed at Mach = 1.4 and a total temperature of T = 950 Kelvin. Far-field acoustic signatures of the hot jet at six polar angles θ = 15˚ to θ = 90˚ from the jet axis) were measured and imaged by the means of continuous wavelet transform in scalograms. The results were compared with experiments from a steady test facility at similar test conditions. Further, the primary characteristics of noise events in jet far-field were compared with analytical models considering wavepacket as the main source of jet noise. The results indicate that higher frequency events at θ = 90˚ occur with a small time shift relative to the low azimuthal mode base event. This phenomenon might be the main reason why the acoustic signal at the side angles behaves more noisily than at low polar angles. [ABSTRACT FROM AUTHOR]

A fast and robust fixed switching frequency peak current controller for DC–AC converters is presented. The proposed method tends to mimic the switching behavior of pulse width modulation (PWM) techniques, so it features all the advantages of peak current controllers (such as simplicity, fast transient, and optimum dynamic response), with the superiority of fixed switching frequency and harmonic free output. The proposed method is a generalized approach that can be applied to different PWM schemes. The method is specifically elaborated for single-phase distributed generation applications, using various inverter topologies and mimicking different PWM schemes. Moreover, adaptive bands are proposed to provide active damping for the controller, to extend use of the proposed method for inverters with LCL output filters. Feasibility and performance of the controller is shown by means of simulations and experiments. [ABSTRACT FROM AUTHOR]

Investigation of genetic relationship among populations has been traditionally based on the analysis of allele frequencies at different loci. The prime objective of this research was to measure the genetic polymorphism of five microsatellite markers (McMA2, BM6444, McMA26, HSC, and OarHH35) and study genetic diversity of 14 sheep types in Iran. Genomic DNA was extracted from blood samples of 565 individuals using an optimized salting-out DNA extraction procedure. The polymerase chain reaction (PCR) was successfully performed with the specific primers. Some locus-population combinations were not at Hardy-Weinberg equilibrium (P < 0:05). The microsatellite analysis revealed high allelic and gene diversity in all 14 breeds. Pakistani and Arabi breeds showed the highest mean number of alleles (11.8 and 11 respectively), while the highest value for polymorphic information content was observed for the Arabi breed (0.88). A UPGMA (unweighted pair group method with arithmetic mean) dendrogram based on the Nei's standard genetic distance among studied breeds showed a separate cluster for Arabi and Pakistani breeds and another cluster for other breeds. The Shannon index (H0) for McMA2, BM6444, McMA26, HSC, and OarHH35 was 2.31, 2.17, 2.27, 2.04 and 2.18, respectively, and polymorphic information content (PIC) values were 0.88, 0.92, 0.87, 0.84, and 0.86 for McMA2, BM6444, McMA26, HSC, and OarHH35, respectively. The high degree of variability demonstrated within the studied sheep types implies that these populations are rich reservoirs of genetic diversity that must be preserved. [ABSTRACT FROM AUTHOR]

Sambucus nigra (elder) are broadly used species to treat microbial infections. The potential antiviral activity and mechanism action of elder fruit (EF) in human epithelium cell (A549) cultures infected with H9N2 influenza virus were determined. The effect of various concentrations of EF on influenza virus replication was examined by using virus titration, quantitative real time RT-PCR, fusion and lipid raft assays following two treatment procedures: A) pre-treated H9N2 virus with each concentration of EF extract and transfection of A549 cell cultures, and B) each concentrations of EF was added to H9N2 virus infected-cell cultures following virus adsorption. In both treatments with lower doses of EF increased viral titer as well as synthesized viral nucleoprotein as indicating the herb had no inhibitory effects on virus replication. In (B) trial with higher doses, 40 and 80 µg/mL of EF, a significant decrease in virus titer and viral protein synthesis were shown in EF treated cells indicating the herb affect either entry of viruses or inhibition virus particle release. The results suggest that EF treatment of the influenza virus infected-human epithelial cells may involve in lipid raft association which function as platform for formation of viral membrane fusion and budding. Differencesin treatment time and dose of EF extract in infected cells with influenza virus have a marked effect on the efficacy of the herb. [ABSTRACT FROM AUTHOR]

This paper proposes a highly scalable sensor design for late transition detection in FPGA based platforms. Transition delays occur because of aging mechanisms such as Biased Temperature Instability (BTI) and Hot Carrier Injection (HCI). We propose a sensor clock (SCLK) that is a function of minimum slack time of a set of paths selected for age monitoring. There will be one such clock for many sensors as are needed in an entire FPGA. Our proposed sensor architecture makes it possible for a single SCLK to be shared by all sensors. Additionally, the proposed sensor occupies one slice (basic FPGA logic block), which leads to low area, power, and performance overhead. Using Artix-7-based board, experimental results demonstrate that the proposed aging sensor detects aging earlier than existing sensors and provides less power and performance overheads. [ABSTRACT FROM AUTHOR]

Laser shock peening (LSP) is known as a post processing surface treatment which can improve the mechanical properties of some materials. Shock waves are generated by confining the laser-induced plasma to cause a large pressure shock wave over a significant surface area. In the present study, effects of LSP on the electrochemical corrosion and micro hardness properties of 316L stainless steel alloy were investigated by changing the laser parameters such as the laser spot size, the average number of impacts, and the laser intensity. Since laser parameters do not cover the desired region of LSP, we have to use the proper design of experiment method, in which the D-optimal design of MATLAB was selected. Results revealed that by increase in irradiance, number of impacts and spot size of laser beam, improvement in the surface micro hardness, and corrosion resistance is achieved. Also, due to unexpected drop into the outcome of our experiments, it was found that the contamination of the transparent overlay and reduction of the absorption coefficient of the absorbent layer play a key role to reduce the efficiency of the mechanical impacts. So, by changing the experimental conditions, even better results are expected. [ABSTRACT FROM AUTHOR]

Objectives: Of all work stressors, occupational stress is the leading cause of many disorders among workers. Drivers are classified as a high risk group for work related stress. This study set out to determine the relationship between risk factors of cardiovascular diseases and occupational stress among drivers.Material and Methods: Two hundred and twenty two Ilam's intercity drivers were selected for the study. For measuring work stress, the Osipow work stress questionnaire was used. After a 10-h fasting period, systolic and diastolic blood pressure was recorded. Intravenous blood samples were taken to determine cholesterol, triglyceride and blood glucose levels. The independent samples t-test and Pearson's correlation test were used to assess the relationship between variables and occupational stress.Results: Seventy-one percent of the intercity drivers suffered from average to acute stress, and 3.1% of them suffered from acute stress. There was no significant relationship between occupational stress and diastolic blood pressure (p = 0.254) among the drivers. Nevertheless, the Pearson's correlation test demonstrated a strong relationship between work stress and blood glucose (p < 0.01), while no strong correlation was found for blood triglycerides and cholesterol levels.Conclusions: Based on the results, high rates of occupational stress were observed in the Ilam's intercity drivers. Occupational stress may have effect on blood glucose levels but the results did not suggest a considerable relationship between risk factors of cardiovascular diseases and occupational stress among intercity drivers. Int J Occup Med Environ Health 2016;29(6):895-901. [ABSTRACT FROM AUTHOR]

Background Pterygium is the human eye lesion whose prevalence in the general population is estimated about 2%. The disease, in extreme phase, can lead to visual disturbance and eventually causes complete loss of vision due to the lesion growth over the papillary axis. Pterygium invasive tissue is a tumor-like tissue that is initially identified and then is attacked by cytotoxic T cells. Cytotoxic T lymphocyte associated antigen 4 (CTLA4), as a modulator molecule of the adaptive immune system, plays a critical role in maintaining peripheral T cell tolerance by diminishing its responsiveness and increasing its activation threshold. The aim of this study is to investigate the association between some epigenetic changes of the CTLA4 gene, such as promoter methylation and gene expression, and pathogenesis of pterygia. Materials and methods Genomic DNA was extracted from 75 formalin-fixed, paraffin-embedded tissues of pterygia and 70 specimens of normal conjunctiva from eyes without pterygium as the control group, collected from Sistan and Baluchestan population. CTLA4 gene promoter methylation was carried out by methylation-specific PCR technique. The gene expression analysis was done on extracted total RNA from 20 healthy and 23 pterygium tissue samples using Real-Time PCR technique. Results Promoter methylation changes of CTLA4 gene were not statistically different in patients with pterygium in comparison with healthy controls (OR = 1.614; 95% CI = 0.57–4.75; P value = 0.37). However, gene expression level of CTLA4 was remarkably different in patients and healthy controls (Mean ± SD: 1.343 ± 0.133 and 2.027 ± 0.219, respectively; P value = 0.009). Conclusion This is a credible evidence of CTLA4 gene expression in human eye tissue. This first hand attempt of investigating the association of epigenetic changes of the CTLA4 gene and pathogenesis of pterygia, indicated a significant intensification of the gene expression of CTLA4 in patients with pterygia. We suggest that increasing CTLA4 gene expression can be a trigger which promotes pterygium enlargement. However, further studies on more populations with larger sample sizes need to be done to verify this hypothesis in the future. [ABSTRACT FROM AUTHOR]