42 results on '"Fabrini, G."'
Search Results
2. Coupling MPC and DP Methods for an Efficient Solution of Optimal Control Problems
- Author
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Alla, A., Fabrini, G., Falcone, M., Bociu, Lorena, editor, Désidéri, Jean-Antoine, editor, and Habbal, Abderrahmane, editor
- Published
- 2016
- Full Text
- View/download PDF
3. The RIBES strategy for ex situ conservation: conventional and modern techniques for seed conservation
- Author
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Magrini S., Bonomi C., Bacchetta G., Bedini G., Borzatti A., Boscutti F., Carasso V., Carta A., Casavecchia S., Casolo V., Ceriani R., Cristaudo A., Di Cecco V., Di Martino L., Digangi I., Fabrini G., Guglielmo F., Mariotti M., Negri V., Porceddu M., Villani M., Zappa E., Salmeri C., Magrini S., Bonomi C., Bacchetta G., Bedini G., Borzatti A., Boscutti F., Carasso V., Carta A., Casavecchia S., Casolo V., Ceriani R., Cristaudo A., Di Cecco V., Di Martino L., Digangi I., Fabrini G., Guglielmo F., Mariotti M., Negri V., Porceddu M., Villani M., Zappa E., and Salmeri C.
- Subjects
conservation strategy ,seed/spore research ,Settore BIO/02 - Botanica Sistematica ,Settore BIO/03 - Botanica Ambientale E Applicata ,Italian flora ,Plant Science ,priority lists ,seed banks - Abstract
The Italian seed bank network (RIBES) aims to improve the quality and safety of the germplasm reserves of native plant species in Italy to ensure the long-term conservation of endangered and/or endemic flora. The strategy includes traditional methods to secure seed conservation. A comprehensive priority list for seed collection is being defined, it was prepared by crossing data of various checklists (red lists, endemics) and will soon be cross-referenced with an updated list of accessions of the whole network. A safety-backup program of duplicates will quickly be implemented to secure the conservation of the most threatened species in at least two seed banks of the network. On the other hand, the RIBES strategy also includes research by applying modern techniques. In collaboration with the Millennium Seed Bank, research on the storage behaviour of seeds and spores through thermal analysis is ongoing to inform conservation. Using the Differential Scanning Calorimetry (DSC), we could evaluate seed lipid properties such as glass transition temperature, melting, crystallization, oxidation behaviour, and thermal stability. Finally, RIBES participates as a co-funder in the LIFE Nature project SEEDFORCE, coordinating 11 seed banks of the network for collecting seeds/spores of 29 threatened species of EU interest.
- Published
- 2022
4. Growth pattern of Bidens cernua L.: relationships between relative growth rate and its physiological and morphological components
- Author
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Gratani, L., Crescente, M. F., Fabrini, G., and Varone, L.
- Published
- 2008
- Full Text
- View/download PDF
5. The RIBES strategy for ex situ conservation: conventional and modern techniques for seed conservation.
- Author
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Magrini, S., Bonomi, C., Bacchetta, G., Bedini, G., Borzatti, A., Boscutti, F., Carasso, V., Carta, A., Casavecchia, S., Casolo, V., Ceriani, R., Cristaudo, A., Di Cecco, V., Di Martino, L., Digangi, I., Fabrini, G., Guglielmo, F., Mariotti, M., Negri, V., and Porceddu, M.
- Subjects
GLASS transition temperature ,SEED harvesting ,NATIVE plants ,ENDANGERED plants ,DIFFERENTIAL scanning calorimetry ,ENDANGERED species ,SEEDS - Abstract
The Italian seed bank network (RIBES) aims to improve the quality and safety of the germplasm reserves of native plant species in Italy to ensure the long-term conservation of endangered and/or endemic flora. The strategy includes traditional methods to secure seed conservation. A comprehensive priority list for seed collection is being defined, it was prepared by crossing data of various checklists (red lists, endemics) and will soon be cross-referenced with an updated list of accessions of the whole network. A safety-backup program of duplicates will quickly be implemented to secure the conservation of the most threatened species in at least two seed banks of the network. On the other hand, the RIBES strategy also includes research by applying modern techniques. In collaboration with the Millennium Seed Bank, research on the storage behaviour of seeds and spores through thermal analysis is ongoing to inform conservation. Using the Differential Scanning Calorimetry (DSC), we could evaluate seed lipid properties such as glass transition temperature, melting, crystallization, oxidation behaviour, and thermal stability. Finally, RIBES participates as a co-funder in the LIFE Nature project SEEDFORCE, coordinating 11 seed banks of the network for collecting seeds/spores of 29 threatened species of EU interest. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
6. Thermal requirements for seed germination of three invasive alien species (IAS)
- Author
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Pepe, M., Gratani, L., Varone, L., and Fabrini, G.
- Subjects
IAS ,temperatures ,seed dormancy ,IAS, germination test, temperatures, seed dormancy ,germination test - Published
- 2019
7. Plant conservation strategy of the Botanical Garden of Rome
- Author
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Tarquini, F., Pepe, Maria, Spoletini, Alessandra, Fabrini, G., Varone, L., and Gratani, L.
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Botanical Garden of Rome ,ex situ conservation ,germplasm bank ,IUCN red list - Published
- 2018
8. The conservation of the Italian Crop Wild Relatives in the RIBES seed-banks: first data to establish national inventories and conservation priorities
- Author
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Magrini, S, Atzeri, P, Bacchetta, G, Bedini, G, Carasso, V, Carta, A, Ceriani, R, Ciancaleoni, S, Di Martino,L, Di Santo, M, Fabrini, G, Forte, L, Gratani, L, Negri, V, Porceddu, M, SALMERI, Cristina Maria Bernardina, Sarigu, R, SCIALABBA, Anna, Taffetani, F, Villani, MC, Zappa, E, Mariotti, M., Magrini, S, Atzeri, P, Bacchetta, G, Bedini, G, Carasso, V, Carta, A, Ceriani, R, Ciancaleoni, S, Di Martino,L, Di Santo, M, Fabrini, G, Forte, L, Gratani, L, Negri, V, Porceddu, M, Salmeri, C, Sarigu, R, Scialabba, A, Taffetani, F, Villani, MC, Zappa, E, and Mariotti, M
- Subjects
Settore BIO/01 - Botanica Generale ,CWR ,Crop wild relatives, Italian flora, RIBES, seed bank ,crop wild relatives ,conservation ,Settore BIO/02 - Botanica Sistematica ,Crop Wild Relatives, CWR, Seed Banks, germplasm ,Seed Banks ,germplasm ,ex situ - Abstract
The authors present the updated results of such census in the Italian Seed Bank Network for native species conservation (RIBES) with an analysis of the contribution to the conservation of the Italian FAO priority CWR. Finally, a national priority list for conservation of CWRs was drawn up and proposed here.
- Published
- 2016
9. The conservation of the endemic Crop Wild Relatives in the RIBES seed-banks: towards a national priority list for the Italian CWRs
- Author
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Magrini, S., Atzeri, P., Bacchetta, G., Bedini, G., Carasso, V., Carta, A., Ceriani, R., Ciancaleoni, S., Di Martino, L., Di Santo, M., Fabrini, G., Forte, L., Gratani, L., Negri, V., Porceddu, M., Salmeri, C., Sarigu, R., Scialabba, A., Taffetani, F., Villani, M., Zappa, E., Mariotti, M., Magrini, S, Atzeri, P, Bacchetta, G, Bedini, G, Carasso, V, Carta, A, Ceriani, R, Ciancaleoni, S, Di Martino,L, Di Santo, M, Fabrini, G, Forte, L, Gratani, L, Negri, V, Porceddu, M, Salmeri, C, Sarigu, R, Scialabba, A, Taffetani, F, Villani, MC, Zappa, E, and Mariotti, M
- Subjects
Settore BIO/01 - Botanica Generale ,CWR ,RIBES seed-banks ,Settore BIO/02 - Botanica Sistematica ,Crop Wild Relatives, CWR, Seed Banks, endemic plants, conservation ,conservation ,crop wild relatives ,Italian CWRs listed ,Seed Banks ,endemic plants ,Crop Wild Relatives ,Banche del germoplasma, Crop Wild Relatives, Endemic, Ribes - Abstract
Data of 620 crop wild relatives of species of food and fodder interest listed in the Annex I of the FAO Treaty (FAO, 2001) were collected within the census carried out by ISPRA, the Italian National Institute for Environmental Protection and Research, in 2014-2015 in order to quantify the extent of CWR representation in the Italian ex situ collections. According to such census, the RIBES network preserve 37% of the Italian CWRs listed in the FAO Treaty: in 14 out of 16 seed-banks are preserved 6,029 accessions of 229 CWR taxa, belonging to 11 families and 57 genera.
- Published
- 2016
10. Kosteletzkya pentacarpos (L.) Ledeb. In: Schede per una Lista Rossa della Flora vascolare e crittogamica Italiana
- Author
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Ercole S., Giacanelli V., Bertani G., Brancaleoni L., Croce A., Fabrini G., Gerdol R., Ghirelli L., Masin R., Mion D., Sburlino G., Tomei P. E., Villani M., Wagensommer R. P., SANTANGELO, ANNALISA, Ercole, S., Giacanelli, V., Bertani, G., Brancaleoni, L., Croce, A., Fabrini, G., Gerdol, R., Ghirelli, L., Masin, R., Mion, D., Santangelo, Annalisa, Sburlino, G., Tomei, P. E., Villani, M., and Wagensommer, R. P.
- Published
- 2013
11. Population genetics and reproductive biology investigations for conservation of Malcolmia littorea : introduction to a multidisciplinary approach
- Author
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De Vitis M., Fabrini G., Seal C., Ulian T, Pritchard H, Mattana E., Mattioni C., Crosti R., and Magrini S.
- Subjects
conservation ,malcolmia littorea - Abstract
Sandy coastal habitats are among the most vulnerable in the world because of their physicaldynamism, and because they are strongly affected by human activities such as construction of harbours, private and tourism infrastructures, mechanical cleaning of beaches, trampling, pollution and invasion by alien plants (Carboni et al., 2009; Defeo et al., 2009). All these factors of disturbance cause and facilitate habitat fragmentation and degradation processes (Carranzaet al., 2010), and as a result, most coastlines are experiencing accelerated rates of erosion(Defeo et al., 2009). The destruction of these habitats is strictly linked with the loss of numerous species which are highly specialized for life in these dynamic systems and are found in no other
- Published
- 2015
12. Are Red List really useful for plant conservation? The New Red List of the Italian Flora as a study case in the perspective of national conservation policies
- Author
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Rossi, G., Montagnani, Chiara, Abeli, T., Gargano, D., Peruzzi, L., Fenu, G., Magrini, S., Gennai, M., Foggi, B., Wagensommer, R. P., Ravera, S., Cogoni, A., Aleffi, M., Alessandrini, A., Bacchetta, G., Bagella, S., Bartolucci, F., Bedini, G., Bernardo, L., Bovio, M., Castello, M., Conti, F., Domina, G., Farris, E., Gentili, R., Gigante, D., Peccenini, Simonetta, Persiani, A. M., Poggio, L., Prosser, F., Santangelo, A., Selvaggi, A., Villani, M. C., Wilhalm, T., Zappa, Elena, Zotti, Mirca, Tartaglini, N., Ardenghi, N. M. G., Blasi, C., Raimondo, F. M., Venturella, G., Cogoni, D., Puglisi, M., Campisi, P., Miserere, L., Perrino, E. V., Strumia, S., Iberite, M., Lucchese, F., Fabrini, G., and Orsenigo, S.
- Subjects
policy species ,IUCN protocol ,Endemic species, GIS database, IUCN protocol, Italy, policy species ,Italy ,GIS database ,Endemic species - Published
- 2014
13. Are Red Lists really useful for plant conservation? The New Red List of the Italian Flora in the perspective of national conservation policies
- Author
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G. Rossi, C. Montagnani, Abeli, T., Gargano, D., Peruzzi, L., Fenu, G., Magrini, S., M, ., Gennai, Foggi, B., Wagensommer, R. P., Ravera, S., Cogoni, A., Aleffi, M., Alessandrini, A., Bacchetta, G., Bagella, S., Bartolucci, F., Bedini, G., Bernardo, L., Bovio, M., Castello, M., Conti, F., Domina, G., Farris, E., Gentili, R., Gigante, D., Peccenini, Simonetta, Persiani, A. M., L, ., Poggio, Prosser, F., Santangelo, A., Selvaggi, A., Villani, M. C., Wilhalm, T., Zappa, E., Zotti, Tartaglini, N., Ardenghi, N. M. G., Blasi, C., Raimondo, F. M., Venturella, G., Cogoni, D., Puglisi, M., Campisi, P., Miserere, L., Perrino, E. V., Strumia, S., Iberite, M., F, ., Lucchese, and Fabrini, G.
- Published
- 2014
14. Edificio Sud del Quartiere delle Case Bizantine
- Author
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Perna, Roberto and Fabrini, G. M.
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Gortina, scavi archeologici ,scavi archeologici ,Gortina - Published
- 2014
15. Strategies for ex situ conservation of Centaurea cineraria subsp. circae (Asteraceae), an endemic plant from Lazio (Italy)
- Author
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Valletta, A., primary, Santamaria, A. R., additional, Fabrini, G., additional, Tocci, N., additional, Filho, V. C., additional, Wagner, T., additional, Brasili, E., additional, and Pasqua, G., additional
- Published
- 2015
- Full Text
- View/download PDF
16. La collezione di Villa 'Due Pini'
- Author
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Antolini, S and Fabrini, G
- Subjects
Settore L-ANT/03 - Storia Romana - Published
- 2004
17. Are Red Lists really useful for plant conservation? The New Red List of the Italian Flora in the perspective of national conservation policies
- Author
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Rossi, G., primary, Montagnani, C., additional, Abeli, T., additional, Gargano, D., additional, Peruzzi, L., additional, Fenu, G., additional, Magrini, S., additional, Gennai, M., additional, Foggi, B., additional, Wagensommer, R.P., additional, Ravera, S., additional, Cogoni, A., additional, Aleffi, M., additional, Alessandrini, A., additional, Bacchetta, G., additional, Bagella, S., additional, Bartolucci, F., additional, Bedini, G., additional, Bernardo, L., additional, Bovio, M., additional, Castello, M., additional, Conti, F., additional, Domina, G., additional, Farris, E., additional, Gentili, R., additional, Gigante, D., additional, Peccenini, S., additional, Persiani, A.M., additional, Poggio, L., additional, Prosser, F., additional, Santangelo, A., additional, Selvaggi, A., additional, Villani, M.C., additional, Wilhalm, T., additional, Zappa, E., additional, Zotti, M., additional, Tartaglini, N., additional, Ardenghi, N.M.G., additional, Blasi, C., additional, Raimondo, F.M., additional, Venturella, G., additional, Cogoni, D., additional, Puglisi, M., additional, Campisi, P., additional, Miserere, L., additional, Perrino, E.V., additional, Strumia, S., additional, Iberite, M., additional, Lucchese, F., additional, Fabrini, G., additional, and Orsenigo, S., additional
- Published
- 2013
- Full Text
- View/download PDF
18. Strategies for ex situ conservation of Centaurea cineraria subsp. circae (Asteraceae), an endemic plant from Lazio (Italy).
- Author
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Valletta, A., Santamaria, A. R., Fabrini, G., Tocci, N., Filho, V. C., Wagner, T., Brasili, E., and Pasqua, G.
- Subjects
ASTERACEAE ,CENTAUREA ,ENDEMIC plants ,PLANT propagation - Abstract
Centaurea cinerariasubsp.circaeis an endemic plant with a distribution area limited to Circeo mountain (Lazio, Italy), whose population was estimated in a very low number of individuals. The aim of this work was to investigateex situconservation strategies such as achene collection andin vitroplant propagation, which will permit to carry out restoration programmes. The test carried out on the achenes demonstrated that only 5.5% of them were morphologically healthy. Seed germination tests showed that seeds do not display dormancy and that germination does not require pre-treatments. The higher germination rate (67.5%) was observed under a photoperiod of 12/12 h (light/dark) and temperature regime +20/+10°C. Thein vitrostudies demonstrated that micropropagation, acclimatization and the transfer outdoors ofC. cinerariasubsp.circaeare not particularly difficult: 74% of shoot explants in a Murashige and Skoog (MS) medium added with 0.5 mg/l benzylaminopurine and 2 mg/l kinetin formed multiple shoots; 100% of shoots rooted in the MS medium added with 0.5 mg/l indole-3-butyric acid and over 90% survived the acclimatization phase. After been transferred outdoors, the totality ofin vitro-propagated plants bloomed and appeared morphologically indistinguishable from wild plants. Preliminary chemical analyses showed a similar profile forin vitro-propagated and wild plants. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
19. Serum gamma-glutamyl-transpeptidase isoforms in alcoholic liver disease
- Author
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Bellini, M, Tumino, E, Giordani, R, Fabrini, G, Costa, F, Galli, R, Rucco, M, Belcari, C, Michelassi, C, Murri, L, Maltinti, G, and Marchi, Santino
- Published
- 1997
20. INCREASED DENSITY OF DOPAMINE D5 RECEPOR IN PERYPHERAL BLOOD LYNPHOCYTES OF MIGRANEURS: A MARKER FOR MIGRAINE?
- Author
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Barbanti, P, Bronzetti, E, Ricci, A, Cerbo, Rosanna, Fabrini, G, Buzzi, Mg, Amenta, F, and Lenzi, Gian Luigi
- Published
- 1996
21. Separation of gamma-glutamiltranspeptidase isoforms in chronic liver diseases
- Author
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Bellini, M., Marchi, Santino, Giordani, R., Fabrini, G., Costa, F., Tumino, E. ., Amato, G., Ricchiuti, A., Spataro, M., Belcari, C., and Maltinti, G.
- Published
- 1996
22. Electrophoretic separation of serum gamma-glutamil-transpeptidase isoenzymes in alcoholic liver disease
- Author
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Marchi, Santino, Bellini, M., Giordani, R., Fabrini, G., Costa, F., Tumino, E., Ricchiuti, A., Amato, G., Spataro, M., Rucco, M., and Maltinti, G.
- Published
- 1995
23. Serum g-glutamil-transpeptidase isoenzymes in cirrhosis and epatocellular carcinoma
- Author
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Bellini, M., Marchi, Santino, Giordani, R., Fabrini, G., Costa, F., Tumino, E., Amato, G., Ricchiuti, A., Rucco, M., Ciccorossi, P., Belcari, C., and Maltinti, G.
- Published
- 1995
24. Separazione delle forme multiple di gamma-glutamiltranspeptidasi sierica: analogie osservate tra alcolisti e pazenti in tattamento con farmaci antiepilettici
- Author
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Bellini, M., Marchi, Santino, Giordani, R., Fabrini, G., Tumino, E., Costa, F., Galli, R., Ricchiuti, A., Amato, G., Belloli, S., Masi, M. C., Massetani, R., Murri, L., and Maltinti, G.
- Published
- 1995
25. Growth analysis of a reestablished population versus a natural population ofBidens cernuaL.
- Author
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Gratani, L., primary, Crescente, M. F., additional, Fabrini, G., additional, Bonito, A., additional, and Varone, L., additional
- Published
- 2009
- Full Text
- View/download PDF
26. SERUM -GLUTAMYL-TRANSPEPTIDASE ISOFORMS IN ALCOHOLIC LIVER DISEASE
- Author
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BELLINI, M., primary, TUMINO, E., additional, GIORDANI, R., additional, FABRINI, G., additional, COSTA, F., additional, GALUI, R., additional, RUCCO, M., additional, BELCARI, C., additional, MICHELASSI, C., additional, MURRI, L., additional, MALTINTI, G., additional, and MARCHI, S., additional
- Published
- 1997
- Full Text
- View/download PDF
27. Growth analysis of a reestablished population versus a natural population of Bidens cernua L.
- Author
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Gratani, L., Crescente, M. F., Fabrini, G., Bonito, A., and Varone, L.
- Subjects
BIDENS ,PLANT populations ,PLANT growth ,PLANT phenology - Abstract
A reintroduction experiment of Bidens cernua L., a species included in the Red List of Italian Flora, was carried out at Lake Posta Fibreno (Lazio, central Italy). There were no significant differences in the length of the phenological phases between the reestablished population (Pr) and the natural one (Pn). The length of the phenological cycle, from seedling emergence to the end of the fruiting phase, was 207 ± 3 days. The relative growth rate in height (RGRH) and relative growth rate in mass (RGRm) were significantly (p < 0.05) higher for Pr (0.047 ± 0.001 cm cm-1 d-1 and 0.057 ± 0.001 g g-1 d-1, respectively) than for Pn (0.045 ± 0.001 cm cm-1 d-1 and 0.055 ± 0.001 g g-1 d-1, respectively). There were significant (p < 0.05) differences for plant height (H) and total leaf area per plant (TLA) between Pr and Pn, the latter having the lower values. Total plant dry mass (PDM) was significantly higher for Pr, and the above-ground/below-ground dry mass ratio was 6.7 ± 0.4 and 4.7 ± 0.2 for Pr and Pn, respectively. On the whole, results demonstrate that the Pr of B. cernua has the potential to develop in a manner that is demographically similar to the Pn present in the Posta Fibreno Lake protected area. Abbreviations: H, plant height; LA, mean leaf area; LM, leaf dry mass; PCA, principal component analysis; PDM, total plant dry mass; Pn, natural population; Pr, reestablished population; RGRH, relative growth rate in plant height; RGRm, relative growth rate in plant dry mass; SLA, specific leaf area; TLA, total leaf area per plant [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
28. A randomized controlled trial of mesentericocaval shunt with autologous jugular vein
- Author
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Stipa, S., Ziparo, Vincenzo, Anza, M., Fabrini, G., and Lupino, R.
- Published
- 1981
29. Kosteletzkya pentacarpos (L.) Ledeb,Kosteletzkya pentacarpos (L.) Ledeb
- Author
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Ercole, S., Giacanelli, V., Bertani, G., Lisa Brancaleoni, Croce, A., Fabrini, G., Gerdol, R., Ghirelli, L., Masin, R., Mion, D., Santangelo, A., Sburlino, G., Tomei, P. E., Villani, M., and Wagensommer, R. P.
30. IDPlanT: the Italian database of plant translocation
- Author
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Fabrizio Buldrini, Filippo Amato, Graziano Rossi, Rossella De Andreis, Rodolfo Gentili, Luigi Minuto, Maria Luisa Borettini, Claudia Angiolini, Giuseppe Fabrini, Silvia Sau, Mirella Di Cecco, Marcello De Vitis, Claudio Magnani, Giulia Albani Rocchetti, Gianluigi Bacchetta, Bruno Enrico Leone Cerabolini, Alessandra Luzzaro, Mauro Mariotti, Aldo Schettino, Franco Rainini, C. Santini, Giampiero Ciaschetti, Marco Landi, Ilaria Bonini, Gianpietro Giusso del Galdo, Angelino Congiu, Mauro Villa, Paolo Castagnini, Angela Deidda, Gabriele Gheza, Alfredo Maccioni, M. F. Crescente, Loretta Gratani, Anna Geraci, Enrico Banfi, Marco D'Antraccoli, A. Bonito, Roberto Crosti, Arianna Amadori, Tonino Loi, Sandra Citterio, F Mantino, Maria Elena Palumbo, Angelo Troia, Sara Magrini, Umberto Clementi, Alba Cuena, Valentino Martinelli, Gaetano Giuseppe La Placa, Lorenzo Peruzzi, Martina D’Agostino, Lisa Brancaleoni, Claudia Alessandrelli, Silvia Paola Assini, Sonia Ravera, Carmelo Gentile, Laura Varone, Angelino Carta, Roberto Fiorentin, Renato Gerdol, Elena Zappa, Luca Paoli, Luciano Di Martino, Maria Silvia Pinna, Simone Orsenigo, Giuseppe Noto, Nicola Sanna, R. M. Ceriani, Rita Accogli, Fabio Conti, Alessandro Silvestre Gristina, Salvatore Pasta, Carlo Dessì, Luigi Forte, Guido Brusa, Gabriele Galasso, Elisabetta Sgarbi, Giuseppe Garfì, Gianniantonio Domina, Giuseppe Fenu, Valter Di Cecco, Daniele Dallai, Donatella Cogoni, Savino Mastrullo, Thomas Abeli, Bruno Foggi, Domitilla Nonis, Fabrizio Bartolucci, Emmanuele Farris, Rosario Schicchi, Francesca Carruggio, Pietro Medagli, Simon Pierce, Attilio Di Giustino, Saverio Sciandrello, Abeli T., D'Agostino M., Orsenigo S., Bartolucci F., Accogli R., Albani Rocchetti G., Alessandrelli C., Amadori A., Amato F., Angiolini C., Assini S., Bacchetta G., Banfi E., Bonini I., Bonito A., Borettini M.L., Brancaleoni L., Brusa G., Buldrini F., Carruggio F., Carta A., Castagnini P., Cerabolini B.E.L., Ceriani R.M., Ciaschetti G., Citterio S., Clementi U., Cogoni D., Congiu A., Conti F., Crescente M.F., Crosti R., Cuena A., D'Antraccoli M., Dallai D., De Andreis R., Deidda A., Dessi C., De Vitis M., Di Cecco V., Di Cecco M., Di Giustino A., Di Martino L., Di Noto G., Domina G., Fabrini G., Farris E., Fiorentin R., Foggi B., Forte L., Galasso G., Garfi G., Gentile C., Gentili R., Geraci A., Gerdol R., Gheza G., Giusso del Galdo G., Gratani L., La Placa G., Landi M., Loi T., Luzzaro A., Alfredo M., Magnani C., Magrini S., Mantino F., Mariotti M.G., Martinelli V., Mastrullo S., Medagli P., Minuto L., Nonis D., Palumbo M.E., Paoli L., Pasta S., Peruzzi L., Pierce S., Pinna M.S., Rainini F., Ravera S., Rossi G., Sanna N., Santini C., Sau S., Schettino A., Schicchi R., Sciandrello S., Sgarbi E., Gristina A.S., Troia A., Varone L., Villa M., Zappa E., Fenu G., Abeli, T., D'Agostino, M., Orsenigo, S., Bartolucci, F., Accogli, R., Albani Rocchetti, G., Alessandrelli, C., Amadori, A., Amato, F., Angiolini, C., Assini, S., Bacchetta, G., Banfi, E., Bonini, I., Bonito, A., Borettini, M. L., Brancaleoni, L., Brusa, G., Buldrini, F., Carruggio, F., Carta, A., Castagnini, P., Cerabolini, B. E. L., Ceriani, R. M., Ciaschetti, G., Citterio, S., Clementi, U., Cogoni, D., Congiu, A., Conti, F., Crescente, M. F., Crosti, R., Cuena, A., D'Antraccoli, M., Dallai, D., De Andreis, R., Deidda, A., Dessi, C., De Vitis, M., Di Cecco, V., Di Cecco, M., Di Giustino, A., Di Martino, L., Di Noto, G., Domina, G., Fabrini, G., Farris, E., Fiorentin, R., Foggi, B., Forte, L., Galasso, G., Garfi, G., Gentile, C., Gentili, R., Geraci, A., Gerdol, R., Gheza, G., Giusso del Galdo, G., Gratani, L., La Placa, G., Landi, M., Loi, T., Luzzaro, A., Alfredo, M., Magnani, C., Magrini, S., Mantino, F., Mariotti, M. G., Martinelli, V., Mastrullo, S., Medagli, P., Minuto, L., Nonis, D., Palumbo, M. E., Paoli, L., Pasta, S., Peruzzi, L., Pierce, S., Pinna, M. S., Rainini, F., Ravera, S., Rossi, G., Sanna, N., Santini, C., Sau, S., Schettino, A., Schicchi, R., Sciandrello, S., Sgarbi, E., Gristina, A. S., Troia, A., Varone, L., Villa, M., Zappa, E., Fenu, G., Abeli, T, D'Agostino, M, Orsenigo, S, Bartolucci, F, Accogli, R, Albani Rocchetti, G, Alessandrelli, C, Amadori, A, Amato, F, Angiolini, C, Assini, S, Bacchetta, G, Banfi, E, Bonini, I, Bonito, A, Borettini, M, Brancaleoni, L, Brusa, G, Buldrini, F, Carruggio, F, Carta, A, Castagnini, P, Cerabolini, B, Ceriani, R, Ciaschetti, G, Citterio, S, Clementi, U, Cogoni, D, Congiu, A, Conti, F, Crescente, M, Crosti, R, Cuena, A, D'Antraccoli, M, Dallai, D, De Andreis, R, Deidda, A, Dessi, C, De Vitis, M, Di Cecco, V, Di Cecco, M, Di Giustino, A, Di Martino, L, Di Noto, G, Domina, G, Fabrini, G, Farris, E, Fiorentin, R, Foggi, B, Forte, L, Galasso, G, Garfi, G, Gentile, C, Gentili, R, Geraci, A, Gerdol, R, Gheza, G, Giusso del Galdo, G, Gratani, L, La Placa, G, Landi, M, Loi, T, Luzzaro, A, Alfredo, M, Magnani, C, Magrini, S, Mantino, F, Mariotti, M, Martinelli, V, Mastrullo, S, Medagli, P, Minuto, L, Nonis, D, Palumbo, M, Paoli, L, Pasta, S, Peruzzi, L, Pierce, S, Pinna, M, Rainini, F, Ravera, S, Rossi, G, Sanna, N, Santini, C, Sau, S, Schettino, A, Schicchi, R, Sciandrello, S, Sgarbi, E, Gristina, A, Troia, A, Varone, L, Villa, M, Zappa, E, and Fenu, G
- Subjects
threatened plant ,Assisted colonisation ,data-sharing ,plant conservation ,plant reintroduction ,population reinforcement ,threatened plants ,Ambientale ,Chromosomal translocation ,Plant Science ,Computational biology ,Data sharing ,Geography ,assisted colonisation, data-sharing, plant conservation, plant reintroduction, population reinforcement, threatened plants ,Ecology, Evolution, Behavior and Systematics - Abstract
IDPlanT is the Italian Database of Plant Translocation, an initiative of the Nature Conservation Working Group of the Italian Botanical Society. IDPlanT currently includes 185 plant translocations. The establishment of a national database on plant translocation is a key step forward in data sharing and techniques improvement in this field of plant conservation. Supplemental data for this article is available online at https://doi.org/10.1080/11263504.2021.1985004.
- Published
- 2021
31. A pragmatic and prudent consensus on the resurrection of extinct plant species using herbarium specimens
- Author
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Gianpietro Giusso del Galdo, Gabriele Galasso, Giulia Caneva, Andrea Mondoni, Giuseppe Fabrini, Domenico Gargano, Gianluigi Bacchetta, Thomas Abeli, Lorenzo Peruzzi, Alfred Mayer, Mauro Iberite, Giuseppe Fenu, Giulia Albani Rocchetti, Sara Magrini, Simone Orsenigo, B. Foggi, Charles C. Davis, C Nepi, Albani Rocchetti, G., Davis, C., Caneva, G., Bacchetta, G., Fabrini, G., Fenu, G., Foggi, B., Galasso, G., Gargano, D., Giusso del Galdo, G., Iberite, M., Magrini, S., Mayer, A., Mondoni, A., Nepi, C., Orsenigo, S., Peruzzi, L., and Abeli, T.
- Subjects
natural history collections ,herbaria ,natural history collection ,social sciences ,Plant Science ,biodiversity loss ,old diaspores ,seed longevity ,species resurrection ,Biology ,humanities ,old diaspore ,biodiversity lo ,Herbarium ,Botany ,Plant species ,Ecology, Evolution, Behavior and Systematics - Abstract
Herbaria may represent remarkable sources of viable diaspores for recovering lost genetic variation and extinct plant species, but the application of rewilding extinct species using these collections has not been explored in detail. De-extinction in plants may be achieved by germinating viable diaspores or culturing tissues preserved in herbarium specimens. Germination of old diaspores (fruits, seeds, spores) preserved in sub-optimal uncontrolled storage conditions demonstrates that the recovery of extinct plants from herbarium specimens may be possible. Plant de-extinction via herbarium specimens relies on the availability of samples containing viable diaspores, and on the inclination of curators and the conservation community to use such material for this purpose. We developed an internet-based survey to assess (i) whether the scientific community would consent to the use of herbarium specimens of extinct species to attempt de-extinction, and (ii) the limitations of removing diaspores from specimens. Despite the risk of potential damages to valuable specimens from historical collections when harvesting diaspores, a consensus for using specimens of extinct plant species emerged. Most respondents would permit the collection of a low number of diaspores, preferably from duplicate specimens and only if the integrity of the specimen is preserved. These considerations would be more restrictive for type specimens and those of historical value. These results help to formalise a decision framework for the grant and use of material from natural history collections and a pragmatic approach to attempt to resurrect extinct species from herbarium specimens.
- Published
- 2021
32. Are Red Lists really useful for plant conservation? The New Red List of the Italian Flora in the perspective of national conservation policies
- Author
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Patrizia Campisi, Liliana Bernardo, L. Miserere, Sara Magrini, Michele Aleffi, Simonetta Peccenini, Lorenzo Peruzzi, Mauro Iberite, Filippo Prosser, Elena Zappa, Sonia Ravera, L. Poggio, Miris Castello, Giuseppe Venturella, T. Wilhalm, Carlo Blasi, Simonetta Bagella, Domenico Gargano, Bruno Foggi, C. Montagnani, Giuseppe Fenu, Annalisa Santangelo, Gianniantonio Domina, Thomas Abeli, M. Bovio, Matilde Gennai, Gianluigi Bacchetta, Giuseppe Fabrini, Francesco Maria Raimondo, Annalena Cogoni, Simone Orsenigo, Maria Cristina Villani, Marta Puglisi, N. Tartaglini, Fabio Conti, Fernando Lucchese, Daniela Gigante, S. Strumia, Alberto Selvaggi, Donatella Cogoni, Enrico V. Perrino, Mirca Zotti, A. Alessandrini, Gianni Bedini, Nicola M. G. Ardenghi, Graziano Rossi, Rodolfo Gentili, Robert P. Wagensommer, Fabrizio Bartolucci, Anna Maria Persiani, Emmanuele Farris, Lucchese, Fernando, Graziano, Rossi, Chiara, Montagnani, Thomas, Abeli, Domenico, Gargano, Lorenzo, Peruzzi, Rossi, G, Montagnani, C, Abeli, T, Gargano, D, Peruzzi, L, Fenu, G, Magrini, S, Gennai, M, Foggi, B, Wagensommer, Rp, Ravera, S, Cogoni, A, Aleffi, M, Alessandrini, A, Bacchetta, G, Bagella, S, Bartolucci, F, Bedini, G, Bernardo, L, Bovio, M, Castello, M, Conti, F, Domina, G, Farrise, Gentili, R, Gigante, D, Peccenini, S, Persiani, Am, Poggio, L, Prosser, F, Santangelo, A, Selvaggi, A, Villani, Mc, Wilhalm, T, Zappa, E, Zotti, M, Tartaglini, N, Ardenghi, Mg, Blasi, C, Raimondo, Fm, Venturella, G, Cogoni, D, Puglisi, M, Campisi, P, Miserere, L, Perrino, Ev, Strumia, S, Iberite, M, Fabrini, G, Orsenigo, S., G., Rossi, C., Montagnani, T., Abeli, D., Gargano, L., Peruzzi, G., Fenu, S., Magrini, M., Gennai, B., Foggi, R. P., Wagensommer, S., Ravera, A., Cogoni, M., Aleffi, A., Alessandrini, G., Bacchetta, S., Bagella, F., Bartolucci, G., Bedini, L., Bernardo, M., Bovio, M., Castello, F., Conti, G., Domina, E., Farri, R., Gentili, D., Gigante, S., Peccenini, A. M., Persiani, L., Poggio, F., Prosser, Santangelo, Annalisa, A., Selvaggi, M. C., Villani, T., Wilhalm, E., Zappa, M., Zotti, N., Tartaglini, N. M. G., Ardenghi, C., Blasi, F. M., Raimondo, G., Venturella, D., Cogoni, M., Puglisi, P., Campisi, L., Miserere, E. V., Perrino, S., Strumia, M., Iberite, F., Lucchese, G., Fabrini, S., Orsenigo, T., Abelia, A., Santangelo, N., Tartaglinia, F. M., Raimondoa, M., Puglisia, P., Campisia, L., Misererea, Strumia, Sandro, Wagensommer, RP, Farris, E, Persiani, AM, Villani, MC, Ardenghi, NMG, Raimondo, FM, Perrino, EV, Lucchese, F, Fabrinit G, Orsenigo, S, Castello, Miri, and G., Fabrinit
- Subjects
policy species ,Flora ,Endemic species, GIS database, IUCN protocol, Italy, policy species ,gis database ,iucn protocol ,endemic species ,italy ,GIS database ,Regional Red List ,Plant Science ,Biology ,red list, Italian flora ,Red List Index ,IUCN protocollo ,Environmental protection ,IUCN Red List ,Endemic species ,IUCN protocol ,Italy ,Endemism ,specie endemiche ,Ecology, Evolution, Behavior and Systematics ,Extinction ,Agroforestry ,Settore BIO/02 - Botanica Sistematica ,endemic species, GIS database IUCN protocol, Itlay, policy specie ,policy specie ,Endemic specie ,Italia ,Taxon ,GIS banca dati ,Threatened species ,Settore BIO/03 - Botanica Ambientale E Applicata ,endemismi, GIS banca dati, IUCN protocollo, Italia, policy specie - Abstract
La nuova Lista Rossa della flora Italiana comprende tutte le "policy" specie italiane e altre specie di nota conservazione e comprende 400 taxa di cui il 65% sono minacciate di estinzione. La Lista Rossa si basa su un enorme data-set georeferenziato utile per gli scopi di conservazione. - The New Red List of the Italian Flora includes all the Italian policy species and other species of known conservation concerns for a total of 400 taxa, 65% of which are threatened with extinction. The Red List is based on a huge georeferenced data-set useful for conservation purposes.
- Published
- 2013
33. Nuovi dati dagli scavi di Suasa sulla genesi e lo sviluppo dell’abitato
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GIORGI, ENRICO, G. DE MARINIS, G.M. FABRINI, G. PACI, R. PERNA, M. SILVESTRINI, and Giorgi, Enrico
- Subjects
Archeologia Urbana, Metoidlogia - Published
- 2012
34. Best practices, errors, and perspectives of half a century of plant translocation in Italy.
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D'Agostino M, Cao Pinna L, Carboni M, Assini S, Bacchetta G, Bartolucci F, Brancaleoni L, Buldrini F, Carta A, Cerabolini B, Ceriani RM, Clementi U, Cogoni D, Conti F, Crosti R, Cuena-Lombraña A, De Vitis M, Di Giustino A, Fabrini G, Farris E, Fenu G, Fiorentin R, Foggi B, Forte L, Garfì G, Gentili R, Giusso Del Galdo GP, Martinelli V, Medagli P, Nonis D, Orsenigo S, Paoli L, Pierce S, Pinna MS, Rainini F, Ravera S, Rossi G, Schettino A, Schicchi R, Troìa A, Varone L, Zappa E, and Abeli T
- Subjects
- Italy, Plants genetics, Biodiversity, Ecosystem, Conservation of Natural Resources methods
- Abstract
Conservation translocations are becoming common conservation practice, so there is an increasing need to understand the drivers of plant translocation performance through reviews of cases at global and regional levels. The establishment of the Italian Database of Plant Translocation (IDPlanT) provides the opportunity to review the techniques used in 186 plant translocation cases performed in the last 50 years in the heart of the Mediterranean Biodiversity Hotspot. We described techniques and information available in IDPlanT and used these data to identify drivers of translocation outcomes. We tested the effect of 15 variables on survival of translocated propagules as of the last monitoring date with binomial logistic mixed-effect models. Eleven variables significantly affected survival of transplants: life form, site protection, material source, number of source populations, propagation methods, propagule life stage, planting methods, habitat suitability assessment, site preparation, aftercare, and costs. The integration of vegetation studies in the selection of suitable planting sites significantly increased the success of translocation efforts. Although posttranslocation watering had a generally positive effect on translocation outcome, other aftercare techniques did not always increase transplant survival. Finally, we found that how funds were spent appeared to be more important than the actual amount spent. Plant translocations in Italy and in the Mediterranean area should account for the complexity of speciation, gene flow, and plant migrations that has led to local adaptations and has important implications for the choice and constitution of source material., (© 2024 Society for Conservation Biology.)
- Published
- 2024
- Full Text
- View/download PDF
35. Co-transcriptional production of programmable RNA condensates and synthetic organelles.
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Fabrini G, Farag N, Nuccio SP, Li S, Stewart JM, Tang AA, McCoy R, Owens RM, Rothemund PWK, Franco E, Di Antonio M, and Di Michele L
- Abstract
Condensation of RNA and proteins is central to cellular functions, and the ability to program it would be valuable in synthetic biology and synthetic cell science. Here we introduce a modular platform for engineering synthetic RNA condensates from tailor-made, branched RNA nanostructures that fold and assemble co-transcriptionally. Up to three orthogonal condensates can form simultaneously and selectively accumulate fluorophores through embedded fluorescent light-up aptamers. The RNA condensates can be expressed within synthetic cells to produce membrane-less organelles with a controlled number and relative size, and showing the ability to capture proteins using selective protein-binding aptamers. The affinity between otherwise orthogonal nanostructures can be modulated by introducing dedicated linker constructs, enabling the production of bi-phasic RNA condensates with a prescribed degree of interphase mixing and diverse morphologies. The in situ expression of programmable RNA condensates could underpin the spatial organization of functionalities in both biological and synthetic cells., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
36. Modular RNA motifs for orthogonal phase separated compartments.
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Stewart JM, Li S, Tang AA, Klocke MA, Gobry MV, Fabrini G, Di Michele L, Rothemund PWK, and Franco E
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- Nanostructures chemistry, Biomolecular Condensates metabolism, Biomolecular Condensates chemistry, Nucleic Acid Conformation, Organelles metabolism, RNA chemistry, RNA metabolism, RNA genetics, Nucleotide Motifs, Aptamers, Nucleotide chemistry, Aptamers, Nucleotide metabolism, Aptamers, Nucleotide genetics
- Abstract
Recent discoveries in biology have highlighted the importance of protein and RNA-based condensates as an alternative to classical membrane-bound organelles. Here, we demonstrate the design of pure RNA condensates from nanostructured, star-shaped RNA motifs. We generate condensates using two different RNA nanostar architectures: multi-stranded nanostars whose binding interactions are programmed via linear overhangs, and single-stranded nanostars whose interactions are programmed via kissing loops. Through systematic sequence design, we demonstrate that both architectures can produce orthogonal (distinct and immiscible) condensates, which can be individually tracked via fluorogenic aptamers. We also show that aptamers make it possible to recruit peptides and proteins to the condensates with high specificity. Successful co-transcriptional formation of condensates from single-stranded nanostars suggests that they may be genetically encoded and produced in living cells. We provide a library of orthogonal RNA condensates that can be modularly customized and offer a route toward creating systems of functional artificial organelles for the task of compartmentalizing molecules and biochemical reactions., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
37. Cation-Responsive and Photocleavable Hydrogels from Noncanonical Amphiphilic DNA Nanostructures.
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Fabrini G, Minard A, Brady RA, Di Antonio M, and Di Michele L
- Subjects
- Cations, DNA chemistry, Hydrogels chemistry, G-Quadruplexes, Nanostructures chemistry
- Abstract
Thanks to its biocompatibility, versatility, and programmable interactions, DNA has been proposed as a building block for functional, stimuli-responsive frameworks with applications in biosensing, tissue engineering, and drug delivery. Of particular importance for in vivo applications is the possibility of making such nanomaterials responsive to physiological stimuli. Here, we demonstrate how combining noncanonical DNA G-quadruplex (G4) structures with amphiphilic DNA constructs yields nanostructures, which we termed "Quad-Stars", capable of assembling into responsive hydrogel particles via a straightforward, enzyme-free, one-pot reaction. The embedded G4 structures allow one to trigger and control the assembly/disassembly in a reversible fashion by adding or removing K
+ ions. Furthermore, the hydrogel aggregates can be photo-disassembled upon near-UV irradiation in the presence of a porphyrin photosensitizer. The combined reversibility of assembly, responsiveness, and cargo-loading capabilities of the hydrophobic moieties make Quad-Stars a promising candidate for biosensors and responsive drug delivery carriers.- Published
- 2022
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- View/download PDF
38. Amphiphilic DNA nanostructures for bottom-up synthetic biology.
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Rubio-Sánchez R, Fabrini G, Cicuta P, and Di Michele L
- Subjects
- DNA chemistry, Nanostructures chemistry, Surface-Active Agents chemistry, Synthetic Biology
- Abstract
DNA nanotechnology enables the construction of sophisticated biomimetic nanomachines that are increasingly central to the growing efforts of creating complex cell-like entities from the bottom-up. DNA nanostructures have been proposed as both structural and functional elements of these artificial cells, and in many instances are decorated with hydrophobic moieties to enable interfacing with synthetic lipid bilayers or regulating bulk self-organisation. In this feature article we review recent efforts to design biomimetic membrane-anchored DNA nanostructures capable of imparting complex functionalities to cell-like objects, such as regulated adhesion, tissue formation, communication and transport. We then discuss the ability of hydrophobic modifications to enable the self-assembly of DNA-based nanostructured frameworks with prescribed morphology and functionality, and explore the relevance of these novel materials for artificial cell science and beyond. Finally, we comment on the yet mostly unexpressed potential of amphiphilic DNA-nanotechnology as a complete toolbox for bottom-up synthetic biology - a figurative and literal scaffold upon which the next generation of synthetic cells could be built.
- Published
- 2021
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39. Idiopathic hypertrophic pachymeningitis: an autoimmune IgG4-related disease.
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De Virgilio A, de Vincentiis M, Inghilleri M, Fabrini G, Conte M, Gallo A, Rizzo MI, and Greco A
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- Diagnosis, Differential, Humans, Meninges pathology, Prognosis, Autoimmune Diseases diagnosis, Autoimmune Diseases drug therapy, Autoimmune Diseases epidemiology, Autoimmune Diseases pathology, Hypertrophy diagnosis, Hypertrophy drug therapy, Hypertrophy epidemiology, Hypertrophy pathology, Immunoglobulin G immunology, Meningitis diagnosis, Meningitis drug therapy, Meningitis epidemiology, Meningitis pathology
- Abstract
Hypertrophic pachymeningitis (HP) is a rare disorder that causes thickening of the dura mater. Inflammatory lesions may be located in the cerebral or spinal dura mater or, less frequently, in both locations simultaneously. Numerous clinico-pathological entities cause thickening of the pachymeninges. Indeed, HP is a potential manifestation of many different diseases, but the diagnosis often remains uncertain. Cases in which the pachymeningitis has no known aetiology are termed "idiopathic" HP (IHP). Recently, it has been suggested that IgG4-related disease represents a subset of cases previously diagnosed as idiopathic hypertrophic pachymeningitis. Little is known regarding the pathogenic events of IHP. In a general theory, the inflammatory infiltrate, mainly consisting of B and T lymphocytes, activates fibroblasts and induces collagen deposition, leading to tissue hypertrophy and increased dural thickness. Clinical manifestations of IHP depend upon the location of the inflammatory lesions and compression of the adjacent nervous structures. Three central pathological features are lymphoplasmacytic infiltration, obliterative phlebitis, and storiform fibrosis. MRI is the examination of choice for the preliminary diagnosis of IHP. Histopathological examination of a biopsy specimen of the dura mater would finally confirm the diagnosis. The differential diagnosis for HP is broad and includes infections, autoimmune disorders, and neoplasia. Currently, there is no consensus about treatment for patients with IHP. There is a preference for glucocorticoid treatment on diagnosis followed by the addition of other immunosuppressive agents in the event of a recurrence. Rituximab is used in patients who did not respond to glucocorticoids or to conventional steroid-sparing agents.
- Published
- 2017
- Full Text
- View/download PDF
40. Serum gamma-glutamyl-transpeptidase isoforms in alcoholic liver disease.
- Author
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Bellini M, Tumino E, Giordani R, Fabrini G, Costa F, Galli R, Rucco M, Belcari C, Michelassi C, Murri L, Maltinti G, and Marchi S
- Subjects
- Adult, Aged, Fatty Liver, Alcoholic diagnosis, Fatty Liver, Alcoholic enzymology, Female, Humans, Liver Cirrhosis, Alcoholic diagnosis, Liver Cirrhosis, Alcoholic enzymology, Liver Diseases, Alcoholic enzymology, Liver Function Tests, Male, Middle Aged, Reference Values, Isoenzymes blood, Liver Diseases, Alcoholic diagnosis, gamma-Glutamyltransferase blood
- Abstract
gamma-Glutamyltranspeptidase (gamma GT) appears in serum in multiple forms; their significance and clinical utility in hepatobiliary and pancreatic diseases are still a matter of controversy. Electrophoretic separation of the multiple forms of gamma GT on agarose gel was performed in 20 alcoholic patients (six with cirrhosis and 14 with fatty liver) and the results compared with those obtained in 50 healthy volunteers, 43 patients affected with chronic hepatitis C, 36 patients with posthepatitic cirrhosis and in 52 epileptic patients on long-term anti-epileptic medication. Multiple forms of gamma GT were separated into several bands (up to 11), labelled 0a, 0b, 1a, 1b, 2a, 2b, 2c, 3a, 3b, 4a, 4b. In the alcoholic patients nine fractions were detected, and the electrophoretic pattern observed was significantly different from that observed in healthy volunteers and in patients with chronic hepatitis C or posthepatitic cirrhosis. No differences were observed in the electrophoretic patterns in the alcohol abusers and epileptic patients. In alcoholic patients significant differences were observed in the electrophoretic patterns in relation to the degree of liver injury; the electrophoretic patterns in patients with alcohol-related cirrhosis and posthepatitic cirrhosis differed significantly. The separation of multiple forms of gamma GT has high sensitivity and good reproducibility. It may be proposed as a complementary test in the diagnosis of alcoholic liver disease.
- Published
- 1997
- Full Text
- View/download PDF
41. A randomized controlled trial of mesentericocaval shunt with autologous jugular vein.
- Author
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Stipa S, Ziparo V, Anzá M, Fabrini G, and Lupino R
- Subjects
- Adolescent, Adult, Aged, Clinical Trials as Topic, Gastrointestinal Hemorrhage surgery, Hepatic Encephalopathy etiology, Humans, Hypertension, Portal complications, Middle Aged, Portasystemic Shunt, Surgical adverse effects, Prospective Studies, Random Allocation, Transplantation, Autologous, Jugular Veins transplantation, Portasystemic Shunt, Surgical methods
- Abstract
After a large uncontrolled experience, in April 1976, a randomized clinical trial between side-to-side portacaval anastomosis and a mesentericocaval shunt with internal jugular vein interposition was initiated. Up to April 1979, 23 patients were operated upon with a mesentericocaval shunt and 26 with a portacaval anastomosis. With a mean follow-up time of 23 months, no statistically significant differences in terms of operative mortality, hepatic encephalopathy and long term survival were found between the two operations. Therefore, a mesentericocaval shunt does not appear to offer effective advantages compared with the portacaval anastomosis, and it should be performed in particular instances in which, for anatomic reasons, a portacaval anastomosis cannot be performed.
- Published
- 1981
42. Reappraisal of serum creatinine as an index of the glomerular filtration rate (measured by external counting).
- Author
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Bianchi C, Cantraine F, De Maertelaer V, Coli A, Palla R, and Fabrini GC
- Subjects
- Evaluation Studies as Topic, Kidney Diseases blood, Creatinine blood, Glomerular Filtration Rate
- Published
- 1976
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