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Your search keyword '"Fonseca, Leonardo Marques da"' showing total 13 results
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13 results on '"Fonseca, Leonardo Marques da"'

1. A novel protocol for the synthesis of 1,2,4-oxadiazoles active against trypanosomatids and drug-resistant leukemia cell lines

Author

Pitasse-Santos, Paulo, Salustiano, Eduardo, Pena, Raynna Bittencourt, Chaves, Otavio Augusto, Fonseca, Leonardo Marques da, da Costa, Kelli Monteiro, Nascimento Santos, Carlos Antonio do, Reis, Jhenifer Santos Dos, Santos, Marcos Andre Rodrigues da Costa, Previato, Jose Osvaldo, Previato, Lucia Mendonca, Freire-de-Lima, Leonardo, Romeiro, Nelilma Correia, Pinto-da-Silva, Lucia Helena, Freire-de-Lima, Celio G, Decote-Ricardo, Debora, and Freire-de-Lima, Marco Edilson

Published
2022

2. A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants

Author

Scovino, Aline Miranda, primary, Dahab, Elizabeth Chen, additional, Diniz-Lima, Israel, additional, de Senna Silveira, Etiele, additional, Barroso, Shana Priscila Coutinho, additional, Cardoso, Karina Martins, additional, Nico, Dirlei, additional, Makhoul, Gustavo José, additional, da Silva-Junior, Elias Barbosa, additional, Freire-de-Lima, Celio Geraldo, additional, Freire-de-Lima, Leonardo, additional, Fonseca, Leonardo Marques da, additional, Valente, Natalia, additional, Nacife, Valeria, additional, Machado, Ana, additional, Araújo, Mia, additional, Vieira, Gustavo Fioravanti, additional, Pauvolid-Corrêa, Alex, additional, Siqueira, Marilda, additional, and Morrot, Alexandre, additional

Published
2024
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3. Increased Trypanosoma cruzi Growth during Infection of Macrophages Cultured on Collagen I Matrix

Author

Logullo, Jorgete, primary, Diniz-Lima, Israel, additional, Rocha, Juliana Dutra B., additional, Cortê-Real, Suzana, additional, Silva-Júnior, Elias Barbosa da, additional, Guimarães-de-Oliveira, Joyce Cristina, additional, Morrot, Alexandre, additional, Fonseca, Leonardo Marques da, additional, Freire-de-Lima, Leonardo, additional, Decote-Ricardo, Debora, additional, and Freire-de-Lima, Celio Geraldo, additional

Published
2023
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5. The Blessed Union of Glycobiology and Immunology: A Marriage That Worked

Author

dos Reis, Jhenifer Santos, primary, Diniz-Lima, Israel, additional, Santos, Marcos André Rodrigues da Costa, additional, Barcelos, Pedro Marçal, additional, da Costa, Kelli Monteiro, additional, Valente, Raphael do Carmo, additional, Chaves, Lorrane de Souza, additional, de Campos, Luma Petel, additional, dos Santos, Ariely Costa, additional, Correia de Lima, Rafaela Gomes, additional, Decote-Ricardo, Debora, additional, Morrot, Alexandre, additional, Previato, Jose Osvaldo, additional, Mendonça-Previato, Lucia, additional, Freire-de-Lima, Celio Geraldo, additional, Fonseca, Leonardo Marques da, additional, and Freire-de-Lima, Leonardo, additional

Published
2023
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7. Cryptococcus: History, Epidemiology and Immune Evasion

Author

Diniz-Lima, Israel, primary, Fonseca, Leonardo Marques da, additional, Silva-Junior, Elias Barbosa da, additional, Guimarães-de-Oliveira, Joyce Cristina, additional, Freire-de-Lima, Leonardo, additional, Nascimento, Danielle Oliveira, additional, Morrot, Alexandre, additional, Previato, Jose Osvaldo, additional, Mendonça-Previato, Lucia, additional, Decote-Ricardo, Debora, additional, and Freire-de-Lima, Celio Geraldo, additional

Published
2022
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8. Bittersweet Sugars: How Unusual Glycan Structures May Connect Epithelial-to-Mesenchymal Transition and Multidrug Resistance in Cancer.

Author

Fonseca, Leonardo Marques da, Diniz-Lima, Israel, da Costa Santos, Marcos André Rodrigues, Franklim, Tatiany Nunes, da Costa, Kelli Monteiro, Santos, Ariely Costa dos, Morrot, Alexandre, Decote-Ricardo, Debora, Valente, Raphael do Carmo, Freire-de-Lima, Celio Geraldo, dos Reis, Jhenifer Santos, and Freire-de-Lima, Leonardo

Subjects
GLYCAN structure, MULTIDRUG resistance, EPITHELIAL-mesenchymal transition, CARBOHYDRATE metabolism, SUGARS
Abstract

Cancer cells are characterized by metabolic reprogramming, which enables their survival in of-ten inhospitable conditions. A very well-documented example that has gained attraction in re-cent years and is already considered a hallmark of transformed cells is the reprogramming of carbohydrate metabolism. Such a feature, in association with the differential expression of en-zymes involved in the biosynthesis of glycoconjugates, generically known as glycosyltransfer-ases, contributes to the expression of structurally atypical glycans when compared to those ex-pressed in healthy tissues. The latest studies have demonstrated that glycophenotypic alterations are capable of modulating multifactorial events essential for the development and/or progres-sion of the disease. Herein, we will address the importance of glycobiology in modern medi-cine, focusing on the ability of unusual/truncated O-linked glycans to modulate two complex and essential phenomena for cancer progression: the acquisition of the multidrug resistance (MDR) phenotype and the activation of molecular pathways associated with the epithelial–mesenchymal transition (EMT) process, an event deeply linked with cancer metastasis. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Supplementary_material – Supplemental material for Resistance to paclitaxel induces glycophenotype changes and mesenchymal-to-epithelial transition activation in the human prostate cancer cell line PC-3

Author

Fonseca, Leonardo Marques Da, Calvalhan, Danilo Macedo, Previato, Jose Osvaldo, Previato, Lucia Mendonça, and Freire-De-Lima, Leonardo

Subjects
FOS: Clinical medicine, Cell Biology, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, Supplementary_material for Resistance to paclitaxel induces glycophenotype changes and mesenchymal-to-epithelial transition activation in the human prostate cancer cell line PC-3 by Leonardo Marques da Fonseca, Danilo Macedo Calvalhan, Jose Osvaldo Previato, Lucia Mendonça Previato and Leonardo Freire-de-Lima in Tumor Biology

Published
2020
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10. Theft and Reception of Host Cell's Sialic Acid: Dynamics of Trypanosoma Cruzi Trans-sialidases and Mucin-Like Molecules on Chagas' Disease Immunomodulation

Author

Fonseca, Leonardo Marques da, primary, da Costa, Kelli Monteiro, additional, Chaves, Victoria de Sousa, additional, Freire-de-Lima, Célio Geraldo, additional, Morrot, Alexandre, additional, Mendonça-Previato, Lucia, additional, Previato, Jose Osvaldo, additional, and Freire-de-Lima, Leonardo, additional

Published
2019
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11. Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses

Author

Morrot, Alexandre, primary, Fonseca, Leonardo Marques da, additional, Salustiano, Eduardo J., additional, Gentile, Luciana Boffoni, additional, Conde, Luciana, additional, Filardy, Alessandra Almeida, additional, Franklim, Tatiany Nunes, additional, da Costa, Kelli Monteiro, additional, Freire-de-Lima, Celio Geraldo, additional, and Freire-de-Lima, Leonardo, additional

Published
2018
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