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In this work, poly(HEMA–APH) nanoparticles were synthesized by surfactant-free emulsion polymerization technique. Magnetic behaviour was introduced by simple addition of Fe3O4 into the polymerization medium. Characterization of the nanoparticle was carried out by FTIR, ESR, SEM, AFM and EDX analyses. These synthesized magnetic nanoparticles were used for adsorption of lysozyme. For this purpose, adsorption conditions were optimized and maximum lysozyme binding capacity was found to be 278.8 mg g−1 polymer in pH 7.0 phosphate buffer at 25∘C. Desorption and reusability properties of the nanoparticles were investigated and lysozyme adsorption efficiency did not change significantly at the end of the 10 successive reuses.

Isolation of DNA is one of the important processes for biotechnological applications such as investigation of DNA structures and functions, recombinant DNA preparations, identification of genetic factors and diagnosis and treatment of genetic disorders. The aim of this study was to synthesis and characterizes the galactoacrylate based nanopolymers with high surface area and to investigate the usability of these synthesized nanopolymers for DNA isolation studies. Nanopolymers were synthesized by the surfactant free emulsion polymerization technique by using the monomers of 2-hydroxyl ethylmethacrylate and 6-O-(2

Aim: Formoterol, N-[2-hydroxy-5-(1-hydroxy-2-(4-methoxyphenyl)-1-methylethyl)amino ethyl] is a bronchodilator used in the treatment of obstructive airways diseases.With this preliminary study,we aimed to develop an effective interaction between formoterol and specifically designed nanoparticle based polymeric structures for it under laboratory conditions.This effort relates to developing a new generation medicinal aerosol formulations with nanocarriers in our following studies. Method: Considering abundance of structural rings of formoterol, we chose tryptophan as one of the well-known hydrophobic polymers. p(HEMA) (2-hydroxyethyl methacrylate) nanoparticles were prepared by surfactant free emulsion polymerization and then grafted with L-Tryptophan according to the procedure [1]. Results: L-Tryptophan graft p(HEMA)nanocarriers were characterized by SEM,FTIR,Zeta Sizer.System parameters such as medium pH,adsorption time,adsorption capacity,initial concentration of formoterol-fumarate were optimized. After the optimization of these parameters, formoterol-fumarate releases studying were carried out in different medium pH and drug release kinetic models were also determined. Conclusion: As a result of our initial laboratory experiments,we observed that there were intense hydrophobic interactions between Graft-Trp-p(HEMA) nanocarriers and formoterol.Preliminary findings of this ongoing study look promising. Formoterol and specifically designed Graft-Trp-p(HEMA) nanocarriers have got interaction on laboratory conditions, thus create a highly bioavailable formulation in the future could be possible.Yet the final optimization works still continue.