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Hidradenitis suppurativa (HS) is a potentially debilitating dermatological disease that negatively impacts patients' quality of life. Severe cases can be further complicated by persistent granulation tissue at the ostia of sinus tracts, which may prove recalcitrant to standard interventions. Herein we report such a case in which a patient experienced significant improvement from severe HS but was left with persistent granulation tissue that complicated his course of recovery. When standard interventions failed, we elected to begin treatment with topical timolol. After three months, the majority of the granulation tissue had regressed and has remained quiescent after 12 months of follow up. The patient has tolerated the treatment well and continues to use topical timolol daily as needed for flares. We believe that topical timolol can provide a practical and painless alternative to current invasive and expensive therapies for persistent granulation tissue associated with severe HS.

A primary linear closure, bilateral advancement flap or a birhombic transposition flap can repair the nasal dorsum defect.[1] The superior standing cone (SC) from these repairs could then serve as a FTSG to repair the nasal supratip defect.[2] The defects' location in this patient precludes a single bilobed or trilobed transposition flap or a dorsal nasal (Rieger) flap. For the patient, the authors performed the EWE flap and closed her defects with subcutaneous 5-0 polydioxanone buried vertical mattress sutures and superficial simple running and simple interrupted 6-0 polypropylene sutures. The flap is advanced using a simple buried suture to close the nasal tip defect, and the rest of the flap and nasal dorsum defect are closed similarly. [Extracted from the article]

The article presents a case study of a 36-year-old pregnant woman with painful erythematous papules on the palms and fingers. Topics include showing tender macules with central areas of porcelain white scarring rimming by telangiectases on the right foot; and punch biopsy of the lesions demonstrating a wedge-shaped area of ischemic necrosis associated with dermal mucin without associated necrobiosis.

The article presents case study of 83‑year‑old male diagnosed with metastatic melanoma. Topics discussed include derangements in renal or liver function or elevated eosinophil counts are symptoms of the disease; eruption of numerous hyperkeratotic papules and nodules on forearms and hands; and treatment of the disease from ipilimumab and triamcinolone inhibitors.

Hidradenitis suppurativa (HS) is a potentially debilitating dermatological disease that negatively impacts patients' quality of life. Severe cases can be further complicated by persistent granulation tissue at the ostia of sinus tracts, which may prove recalcitrant to standard interventions. Herein we report such a case in which a patient experienced significant improvement from severe HS but was left with persistent granulation tissue that complicated his course of recovery. When standard interventions failed, we elected to begin treatment with topical timolol. After three months, the majority of the granulation tissue had regressed and has remained quiescent after 12 months of follow up. The patient has tolerated the treatment well and continues to use topical timolol daily as needed for flares. We believe that topical timolol can provide a practical and painless alternative to current invasive and expensive therapies for persistent granulation tissue associated with severe HS. [ABSTRACT FROM AUTHOR]

The article presents an case study of 79-year-old woman with type 2 diabetes mellitus, peptic ulcer disease, and hypertension was referred to the dermatology clinic due to concern for allergic contact dermatitis limited to the area of and adjacent to a well healed surgical wound. It mentions subepidermal bullae containing eosinophils and neutrophils, most consistent with a bullous drug eruption and areas of superficial erosion with serum crust.

Dermatologic manifestations of cystic fibrosis (CF) include nutrient deficiency dermatoses, vasculitis, transient reactive papulotranslucent acrokeratodema, digital clubbing, and increased rates of atopy and drug reactions. Few cases of a characteristic eruption in patients with episodic arthritis of CF have been described with prior reports primarily occurring outside of the dermatology literature. We report four cases consistent with this presentation to add to the literature and propose a new and unifying name to recognize this entity as cystic fibrosis dermatitis arthritis syndrome (CF‐DAS). Clinical suspicion should remain high in young female patients with cystic fibrosis presenting with episodic joint pain and rash, independent of pulmonary exacerbations. [ABSTRACT FROM AUTHOR]

Herpes zoster (HZ), or shingles, is commonly seen in older adults but does occur in children. Routine administration of the varicella vaccine started in 1995 in the United States; since then, the incidence of varicella and HZ has declined. We report a case of HZ in an otherwise healthy 19-month-old boy who had been vaccinated at 13 months of age and recovered fully after acyclovir treatment. We review previously reported cases of HZ in healthy vaccinated children.