Search

By a high-temperature reaction of rhenium(III) iodide and red phosphorus with an excess of sodium cyanide followed by recrystallization from an aqueous solution a new tetrahedral [{Re4(PO)4}(CN)12]8– anionic cluster complex is obtained. It is isolated as a salt of the composition Na8[{Re4(PO)4}(CN)12] 18H2O·MeOH. The structure of the obtained compound is determined by X-ray crystallography. The compound crystallizes in the monoclinic crystal system, P21/n space group, unit cell parameters a = 26.826(3) A, b = 11.4975(12) A, c = 29.141(3) A, β = 97.879(2)°, V = 8903.2(16) A3, Z = 8.

Der Nutzen und die Risiken von Live-Ubertragungen von Operationen und Interventionen sind umstritten. Die Deutsche Gesellschaft fur Chirurgie hat daher die Notwendigkeit gesehen, in einem Positionspapier eindeutige Regeln fur den Einsatz von Live Ubertragungen zu publizieren. Dies geschieht zum Schutz der Patienten und zur Unterstutzung der beteiligten Chirurgen.

The measurement of the jet cross sections by the H1 collaboration had been compared to various predictions including the next-to-next-to-leading order (NNLO) QCD calculations which are corrected in this erratum for an implementation error in one of the components of the NNLO calculations. The jet data and the other predictions remain unchanged. Eight figures, one table and conclusions are adapted accordingly, exhibiting even better agreement between the corrected NNLO predictions and the jet data.

Charged particle multiplicity distributions in positron-proton deep inelastic scattering at a centre-of-mass energy $$\sqrt{s}=319$$ s = 319 GeV are measured. The data are collected with the H1 detector at HERA corresponding to an integrated luminosity of 136 pb$$^{-1}$$ - 1 . Charged particle multiplicities are measured as a function of photon virtuality $$Q^2$$ Q 2 , inelasticity y and pseudorapidity $$\eta $$ η in the laboratory and the hadronic centre-of-mass frames. Predictions from different Monte Carlo models are compared to the data. The first and second moments of the multiplicity distributions are determined and the KNO scaling behaviour is investigated. The multiplicity distributions as a function of $$Q^2$$ Q 2 and the Bjorken variable $$x_{\mathrm{bj}}$$ x bj are converted to the hadron entropy $$S_{\mathrm{hadron}}$$ S hadron , and predictions from a quantum entanglement model are tested.

The European physical journal / C 81(8), 738 (2021). doi:10.1140/epjc/s10052-021-09394-0, Published by Springer, Heidelberg

Exclusive photoproduction of $${{\rho ^0}} (770)$$ ρ 0 ( 770 ) mesons is studied using the H1 detector at the ep collider HERA. A sample of about 900,000 events is used to measure single- and double-differential cross sections for the reaction $$\gamma p \rightarrow \pi ^{+}\pi ^{-}Y$$ γ p → π + π - Y . Reactions where the proton stays intact ($${{{m_Y}} {=}m_p}$$ m Y = m p ) are statistically separated from those where the proton dissociates to a low-mass hadronic system ($$m_p{ m p < m Y < 10 GeV ). The double-differential cross sections are measured as a function of the invariant mass $$m_{\pi \pi }$$ m π π of the decay pions and the squared 4-momentum transfer t at the proton vertex. The measurements are presented in various bins of the photon–proton collision energy $${{W_{\gamma p}}} $$ W γ p . The phase space restrictions are $$0.5\le m_{\pi \pi } \le 2.2~{{\text {GeV}}} $$ 0.5 ≤ m π π ≤ 2.2 GeV , $$\vert t\vert \le 1.5~{{\text {GeV}^2}} $$ | t | ≤ 1.5 GeV 2 , and $$20 \le W_{\gamma p} \le 80~{{\text {GeV}}} $$ 20 ≤ W γ p ≤ 80 GeV . Cross section measurements are presented for both elastic and proton-dissociative scattering. The observed cross section dependencies are described by analytic functions. Parametrising the $${m_{\pi \pi }}$$ m π π dependence with resonant and non-resonant contributions added at the amplitude level leads to a measurement of the $${{\rho ^0}} (770)$$ ρ 0 ( 770 ) meson mass and width at $$m_\rho = 770.8{}^{+2.6}_{-2.7}~({\text {tot.}})~{{\text {MeV}}} $$ m ρ = 770.8 - 2.7 + 2.6 ( tot. ) MeV and $$\Gamma _\rho = 151.3 {}^{+2.7}_{-3.6}~({\text {tot.}})~{{\text {MeV}}} $$ Γ ρ = 151.3 - 3.6 + 2.7 ( tot. ) MeV , respectively. The model is used to extract the $${{\rho ^0}} (770)$$ ρ 0 ( 770 ) contribution to the $$\pi ^{+}\pi ^{-}$$ π + π - cross sections and measure it as a function of t and $${W_{\gamma p}}$$ W γ p . In a Regge asymptotic limit in which one Regge trajectory $$\alpha (t)$$ α ( t ) dominates, the intercept $$\alpha (t{=}0) = 1.0654\ {}^{+0.0098}_{-0.0067}~({\text {tot.}})$$ α ( t = 0 ) = 1.0654 - 0.0067 + 0.0098 ( tot. ) and the slope $$\alpha ^\prime (t{=}0) = 0.233 {}^{+0.067 }_{-0.074 }~({\text {tot.}}) ~{{\text {GeV}^{-2}}} $$ α ′ ( t = 0 ) = 0.233 - 0.074 + 0.067 ( tot. ) GeV - 2 of the t dependence are extracted for the case $$m_Y{=}m_p$$ m Y = m p .

Eosinophilic pneumonia is an acute respiratory illness of varying severity that is characterized by an increased infiltration of eosinophils in lung tissue or bronchoalveolar lavage fluid. The larg...

Es gibt eine Vielzahl an Tumoren und tumorartigen Veranderungen mit unterschiedlichem biologischem Verhalten, die die Skelettmuskulatur befallen. Das Ziel dieser Arbeit ist es, unterschiedliche Lasionen der Skelettmuskulatur aufzuzeigen und anhand ihrer radiologischen Muster zu klassifizieren. Lasionen der Skelettmuskulatur konnen sich solide, liquide/semiliquide oder fettaquivalent manifestieren sowie auch als diffuse Muskelauftreibungen und als Muskelkalzifikationen. Daruber hinaus gibt es Lasionen mit Mischverhalten der genannten Veranderungen. Benigne und maligne Veranderungen konnen die gleichen radiologischen Muster aufweisen, weshalb eine sichere Differenzierung haufig schwierig ist. Eine systematische radiologische Beschreibung und wenn moglich Einordnung bez. Atiologie und Dignitat ist in Abhangigkeit der Anamnese notwendig, um eine konsekutive histologische Sicherung zu empfehlen oder unnotige invasive Eingriffe zu verhindern.

The digitalization process is currently on everyone's lips and sweeping changes in the field of public health and especially in surgery are to be expected within the next few years. Besides general issues, such as electronic health records and medical information systems, artificial intelligence, robotics and model-based surgery will decisively impact on the daily routine. In order to provide the necessary knowledge base, to point out related risks and chances and also to define fields of action for surgery, the German Society of Surgery commissioned a position paper on digitalization. A first appraisal in form of an online survey is the subject of this article.This article is based on an online survey of the members of the German Society of Surgery and selected members of other related societies. The survey asked for the members' personal assessment concerning different aspects of the digitalization process and the respective state of knowledge as well as the impact on the field of surgery.A total of 296 members contributed to this survey. According to their assessment, digitalization in surgery is currently associated with terms such as electronic health records and medical information systems but they also assume a relevant influence on their own activities and on the fields of interventional medicine and surgery. A relevant need for improvement of the current state of knowledge was highlighted, not only for general aspects of digitalization but also for surgically relevant issues in particular. The vast majority of interviewed members saw digitalization more as a chance for improvement than as a risk factor.According to the views of interviewed members of the German Society of Surgery the process of digital transformation will significantly impact the field of surgery. All those involved should feel responsible to contribute to and guide this process in order to maintain the surgically inherent requirements and to protect patient safety. The position paper on digitalization can serve as a basis and should define concrete recommendations for action. In the sense of an academic approach the new possibilities should be critically evaluated with respect to suitability and should be exclusively confined to applications that are beneficial to ourselves and to our patients.

The parameters of the electroweak theory are determined in a combined electroweak and QCD analysis using all deep-inelastic $e^+p$ and $e^-p$ neutral current and charged current scattering cross sections published by the H1 Collaboration, including data with longitudinally polarised lepton beams. Various fits to Standard Model parameters in the on-shell scheme are performed. The mass of the W boson is determined as $m_W=80.520\pm 0.115~\mathrm {GeV} $ . The axial-vector and vector couplings of the light quarks to the Z boson are also determined. Both results improve the precision of previous H1 determinations based on HERA-I data by about a factor of two. Possible scale dependence of the weak coupling parameters in both neutral and charged current interactions beyond the Standard Model is also studied. All results are found to be consistent with the Standard Model expectations.

Die Versorgung von Menschen mit schizophrenen Erkrankungen weist eine Reihe von gravierenden Defiziten auf. Mit Einfuhrung der Integrierten Versorgung sind neue Versorgungsansatze erprobt worden. Von der Einfuhrung des neuen Vergutungssystems fur die stationare psychiatrische und psychosomatische Versorgung (PEPP) sind weitere Impulse fur strukturelle Veranderungen zu erwarten. Vor diesem Hintergrund wurden drei Szenarien einer zukunftigen Schizophrenie-Versorgung entwickelt und mit einem Beirat von Experten sowie im Rahmen einer Fachtagung diskutiert. Der Beitrag umreist zunachst die wichtigsten Problemschwerpunkte in der aktuellen Versorgung. Anschliesend werden die drei Szenarien als mogliche Losungsansatze vorgestellt. Aus der Diskussion der Starken und Schwachen jedes Szenarios werden ubergreifende Handlungsempfehlungen entwickelt, die im Rahmen eines „Nationalen Versorgungsprogramms Schizophrenie“ umgesetzt werden sollten.

There are many different tumors and tumor-like lesions with variable biological behavior that may affect the skeletal musculature. The aim of this study was to review the different intramuscular lesions and to provide a classification based on their radiological patterns. Intramuscular lesions can present as solid, liquid, semiliquid or fat equivalent manifestations and also as diffuse muscle enlargement and muscle calcification. Additionally, lesions with mixed patterns of the aforementioned alterations can also occur. Benign and malignant muscle lesions can often manifest with identical radiological patterns, which is why a certain differentiation is often difficult. A systematic radiological description and when possible assignment with respect to etiology and dignity depending on the patient history is necessary in order to recommend a subsequent histological confirmation or to avoid unnecessary confirmation.

Hintergrund: Nach Einfuhrung des MELD-Scores haben sich die Uberlebensraten nach Lebertransplantation (LTX) in Deutschland verschlechtert. Bestehender Organmangel, kurzere Uberlebensraten nach LTX und Regelverstose bei der Leberallokation stellen relevante Herausforderungen dar. Mit der vorliegenden Arbeit wurden die masgeblichen deutschen Lebertransplantationsakteure erstmals mittels eines strukturierten Ansatzes in die Bewertung und Entwicklung von Regelungen der Organallokation einbezogen. Ziel dieses Ansatzes war es, basierend auf den Kenntnissen der tatsachlich Handelnden, in freier und anonymer Weise mogliche Verbesserungspotentiale aufzuzeigen. Methode: Die Datenerhebung wurde mittels einer standardisierten, anonymen Befragung aller LTX-Zentren in Deutschland durchgefuhrt. Ergebnisse: Die Rucklaufquote betrug 75 %, 35 von 36 Teilnehmern beantworteten mehr als 75 % aller Fragen. Folgende Kernaussagen wurden herausgearbeitet: Eine Mindestmenge an LTX pro Zentrum erscheint sinnvoll, ein monetarer Mengenanreiz darf nicht bestehen. Das Ziel einer LTX stellt eine Lebensverlangerung sowie die gesellschaftliche und berufliche Wiedereingliederung dar. Qualitatsmanagement und transparente LTX-Register sind Voraussetzungen fur eine adaquate Organ- und Ressourcenallokation und bestmogliche Transplantationsergebnisse. Schlussfolgerung: Die deutschen Lebertransplanteure haben sich im Rahmen eines partizipativen Verfahrens fur eine Transparenz der Organallokation und systematische Evaluationen der Transplantationszentren ausgesprochen. Neben einer Starkung des Vertrauens erwarten sie hiervon Anstose fur die Entwicklung eines Scores, der die Erfolgsaussichten einer LTX zuverlassiger abbildet und damit ethische und verfassungsrechtliche Zweifel ausraumt.

The measurement of diffuse refl ectance spectra below 230 nm for ceramic luminescent materials is usually not performed although it is of tremendous interest, e.g., to determine their quantum effi ciency upon VUV excitation. In contrast, the recording of VUV excitation spectra is well established, e.g., to evaluate VUV phosphors. The lack of access to diffuse powder refl ection spectra in this range is caused by the absorption edge (optical band gap) of the most common refl ectance standards; for instance, BaSO4 or CaCO3–VUV photons with energies higher than the absorption edge are not refl ected but absorbed and thus not amenable to detection in a synchronous scan. The measurement technique presented in this paper allows monitoring refl ection properties of powder samples in the range from 120 to 300 nm (10.3 to 4.1 eV). To this end, all VUV photons refl ected by the sample are converted into visible photons, which are collected in an Ulbricht sphere and fi nally counted by a photomultiplier tube (PMT). This requires a custom-built integrating sphere, viz. one that is coated with a (V)UV to Vis converter, e.g., a phosphor such as BaMgAl10O17:Eu2+ (BAM:Eu) showing a spectrally independent and high light output in the respective wavelength range. This paper sketches the technique and procedure for recording VUV refl ection spectra and shows the results for several standard phosphors. It also reveals the limits of this new technique.

The majority of recommendations in the current S3 guideline on the diagnosis and treatment of gastric carcinoma are based on good clinical practice and lack supporting randomized studies. With the development of endoscopic resection and multimodal treatment concepts, pretherapeutic tumor staging has gained in importance. However, the accuracy of present imaging modalities is still limited with a tendency towards overstaging of locally advanced tumors. Extended lymph node dissection cannot be recommended in cases with advanced lymph node involvement. In cardiac cancer retroperitoneal lymphatic spread to the left renal vein is an early event and should thus not be classified as stage IV disease. In cases of intra-abdominal gastrectomy a pouch reconstruction should be considered in cases with a good overall prognosis. Subgroup analyses indicate a differential therapeutic effect of the established perioperative chemotherapy depending on the location of the primary tumor. There is also good evidence for an additional beneficial effect of radiotherapy in combination with chemotherapy.

Esophagectomy is considered to be a high risk procedure regarding postoperative morbidity and mortality. Therefore, in Germany, these operations are limited to hospitals fulfilling a minimum quantity. This systematic review focuses on risk and complication management regarding the impact of perioperative nutritional therapy, including the recent S3-guideline recommendations and comments of the German Working Group of Medical Societies (AWMF) which were established with contributions from the authors.

The current German S3 guideline represents the recommendations for the diagnosis and therapy of squamous cell carcinomas and adenocarcinomas of the esophagus based on evidence from the literature and interdisciplinary expert consensus. Esophagogastroscopy with biopsy, endosonography, and spiral CT scan of the neck, thorax, and abdomen are decisive in staging and the choice of therapy. For a curative approach, surgery, especially transthoracic esophagectomy and gastric pull-up, is the most important therapeutic option, except in the case of mucosal carcinomas or cervical squamous cell carcinomas. The significance of total minimally invasive esophageal resection or a hybrid technique is still uncertain. In category cT3 or resectable cT4 tumors, neoadjuvant radiochemotherapy should be performed in squamous cell carcinomas or adenocarcinomas. Alternatively, perioperative chemotherapy can be carried out in adenocarcinoma. Palliative resections should be avoided and replaced by interventional procedures for palliation.

Signals of QCD instanton-induced processes are searched for in neutral current deep-inelastic scattering at the electron-proton collider HERA in the kinematic region defined by the Bjorken-scaling variable $x > 10^{-3}$, the inelasticity $0.2< y < 0.7$ and the photon virtuality $150 < Q^2 < 15000$ GeV$^2$. The search is performed using H1 data corresponding to an integrated luminosity of ~$351$ pb$^{-1}$. No evidence for the production of QCD instanton-induced events is observed. Upper limits on the cross section for instanton-induced processes between $1.5$~pb and $6$~pb, at $95\%$~ confidence level, are obtained depending on the kinematic domain in which instantons could be produced. Compared to earlier publications, the limits are improved by an order of magnitude and for the first time are challenging theory predictions.

BACKGROUND: The overall prognosis of gastric cancer with an overall 5-year survival of 25% is still poor despite improvements of the surgical and perioperative procedures. To improve the surgical treatment results other therapeutic options as chemo- and/or radiotherapy have been investigated for more than 20 years. METHODS: After a literature review, the results of actual trials of multimodality treatment were analysed and described. RESULTS: Adjuvant treatment was less effective compared with neoadjuvant or perioperative chemotherapy performed in advanced tumour categories T3/4. Actual trials could show that the rate of curative (R0) resection can be augmented resulting in an increase of the overall 5-year survival rate of more than 10 %. CONCLUSION: To confirm this trend, further studies with high pathological and surgical quality control are necessary as well as a more exact definition of prediction and evaluation of the response following chemotherapy.

Compounds containing the (XO or S) unit yield negative-ion spectra, which are dominated by peaks arising by α or s cleavage to PX. Molecular ions are generally absent in these spectra, except in cases where the molecule contains an additional electron-capture group (e.g. p-nitrophenyl). Simple cleavage is accompanied by a characteristic rearrangement reaction for certain compounds containing the -C(X)-Y-P(S) unit (XO or S, YO, S, or NH); the rearrangement is most pronounced when YNH. Compounds containing the PS moiety are prone to thermal decomposition; such decompositions may be detected by the presence of peaks corresponding to Sn (n=1-10) in the negative-ion spectra.

A number of N,N-diacetylamines has been prepared in generally high yields by acetylation of primary amines with acetic anhydride in presence of magnesium and catalytic amounts of Cu(OAc)2. The general physical and also some chemical properties of N,N-diacetylamines are presented together with pertinent spectroscopic data.

By heating (100-160 °C) N-alkylsubstituted alicyclic amines, R-N(CH2) (n = 4, 5, 6), with elemental sulfur in HMPA, oxidation of the amine ring afforded the corresponding thiolactams, 2. Thus N-benzylthiopyrrolidone, 2a (67%), N-(2-phenylethyl)-2-thiopyrrolidone, 2b (71%), N-benzyl-2-thiopiperidone, 2c (27%), N-(2-phenylethyl)-2-thiopiperidone, 2d (63%), N-methyl-e-thiocaprolactame, 2e (45%), and N-(2-phenylethyl)-e-thiocaprolactame, 2f (10%) were prepared. From oxidation of N-alkylhexahydroazepines and N-alkyloctahydroazocines were produced as the main products bis (1-alkyl-2-ethyl-3-pyrrolyl) polysulfides, 3, and bis (1-alkyl-2-(n-propyl)-3-pyrrolyl) polysulfides, 4, respectively. Reduction of these with Zn, HCl or LiAlH4 followed by methylation (MeI) gave the corresponding 3-(methylthio)-pyrroles, 8 in 20-49% overall yields. 1-(2-Phenylethyl)-2-ethyl-3-mercaptopyrrole, 7, was isolated in 48% yield from reduction (Zn, HCl) of the corresponding dipyrrolyl polysulfide. 3, 4-Dithiolated pyrroles were recognized in most reactions and isolated in some cases. The structures of the pyrroles were established by 1H NMR, 13C NMR, and MS.

N-benzylacetamides, when refluxed in HMPA, undergo a rearrangement reaction by which 3-phenylpropionitriles are produced.

Esophageal cancer: Clinical Practice Guidelines for diagnosis, treatment and follow-up M. Stahl, W. Budach, H.-J. Meyer & A. Cervantes On behalf of the ESMO Guidelines Working Group* Department of Medical Oncology and Centre of Palliative Care, Kliniken Essen-Mitte, Essen; Department of Radiation Oncology, University of Dusseldorf, Dusseldorf; Department of Surgery, Stadt Klinikum Solingen, Germany; Department of Hematology and Medical Oncology, INCLIVA, University of Valencia, Valencia, Spain

Resezierende Eingriffe in der Magen- und Pankreaschirurgie, vor allem bei malignen Tumoren, sind in den letzten Jahren deutlich sicherer geworden. Die postoperative Letalitat betragt in erfahrenen Zentren weniger als 5%. Die Komplikationsrate in der fruhen postoperativen Phase konnte allerdings nicht in gleicher Weise reduziert werden und liegt weiterhin zwischen 15 und mehr als 40%. Unabhangig von divergierenden Definitionen der postoperativen Morbiditat konnen nach Magenresektion und (erweiterter) Gastrektomie verschiedene intra- und extraluminare Storungen auftreten. Als schwerwiegendste Komplikation ist zweifelsohne die Anastomoseninsuffizienz der Osophagojejunostomie einzustufen, deren Verlauf vor allem durch endoskopische und interventionelle Masnahmen positiv beeinflusst werden kann. Nach der Pankreaskopfresektion konnen ebenfalls Insuffizienzen der Pankreo- oder Pankreatikojejunostomie bzw. der biliodigestiven Anastomose auftreten, die sich in mehr als 70% der Falle durch konservative und interventionelle Verfahren beherrschen lassen. Am gefurchtesten sind bei dieser Komplikation und resultierender lokaler Peritonitis die spaten postoperativen Arrosionsblutungen, die interventionell-radiologisch behandelt werden konnen bzw. bei nicht erfolgreicher Therapie einer operative Reintervention verlangen. Sowohl nach Resektionen des Magens als auch des Pankreas sind funktionelle Komplikationen zu erwarten, die aber bei rechtzeitiger Diagnose uberwiegend konservativ zu beherrschen sind.

A 35-year-old man reported persistent exertional dyspnoea and pressure sensation over the left chest for the last six weeks. On auscultation there were diminished breath sounds over the right base. Chest X-ray demonstrated a 10 cm large ventral paracardiac shadow on the right. Computed tomography suggested a hernia of the foramen of Morgagni; persisting symptoms indicated a laparotomy. This revealed an opening of about 1.5 cm in the right substernocostal triangle through which the entire greater omentum had herniated into the thorax. The omentum was repositioned and the hernial defect closed by direct suture. The postoperative course was without complication and the patient was discharged after seven days.

In a prospective multi-centre study data were collected on 1,999 patients (1273 men, 726 women; mean age 62.3 [19-99] years) with gastric carcinoma, admitted to one of 19 surgical departments in Germany between 1.4. 1986 to 30. 6. 1989. Previously treated patients as well as those with synchronous or metachronous tumours and carcinoma of the gastric stump had been excluded. The resection rate for gastric carcinoma was 82.7%, i.e. resection was no longer possible because of the advanced tumour stage in nearly 20%. The tumour was located in the upper third of the stomach in 30%, the antrum in 26.3%. An intestinal type of growth was present in 51.9%. An early carcinoma was diagnosed in 16.9% of operated patients; it had already metastasized to regional lymph nodes in 16.5%. Nearly 70% of patients with resectable tumours had metastases to the regional lymph-nodes, with distant metastases in 30%. An advanced tumour stage (UICC stage IIIB or IV) was present in 43%. Exclusively surgical treatment is not effective in these cases.

A first measurement is presented of exclusive photoproduction of $$\rho ^0$$ mesons associated with leading neutrons at HERA. The data were taken with the H1 detector in the years 2006 and 2007 at a centre-of-mass energy of $$\sqrt{s}=319$$ GeV and correspond to an integrated luminosity of 1.16 pb $$^{-1}$$ . The $$\rho ^0$$ mesons with transverse momenta $$p_T0.35$$ , are detected in the Forward Neutron Calorimeter. The phase space of the measurement is defined by the photon virtuality $$Q^2 < 2$$ GeV $$^2$$ , the total energy of the photon–proton system $$20 < W_{\gamma p}< 100$$ GeV and the polar angle of the leading neutron $$\theta _n < 0.75$$ mrad. The cross section of the reaction $$\gamma p \rightarrow \rho ^0 n \pi ^+$$ is measured as a function of several variables. The data are interpreted in terms of a double peripheral process, involving pion exchange at the proton vertex followed by elastic photoproduction of a $$\rho ^0$$ meson on the virtual pion. In the framework of one-pion-exchange dominance the elastic cross section of photon-pion scattering, $$\sigma ^\mathrm{el}(\gamma \pi ^+ \rightarrow \rho ^0\pi ^+)$$ , is extracted. The value of this cross section indicates significant absorptive corrections for the exclusive reaction $$\gamma p \rightarrow \rho ^0 n \pi ^+$$ .

A combination is presented of all inclusive deep inelastic cross sections previously published by the H1 and ZEUS collaborations at HERA for neutral and charged current $e^{\pm}p$ scattering for zero beam polarisation. The data were taken at proton beam energies of 920, 820, 575 and 460 GeV and an electron beam energy of 27.5 GeV. The data correspond to an integrated luminosity of about 1 fb$^{-1}$ and span six orders of magnitude in negative four-momentum-transfer squared, $Q^2$, and Bjorken $x$. The correlations of the systematic uncertainties were evaluated and taken into account for the combination. The combined cross sections were input to QCD analyses at leading order, next-to-leading order and at next-to-next-to-leading order, providing a new set of parton distribution functions, called HERAPDF2.0. In addition to the experimental uncertainties, model and parameterisation uncertainties were assessed for these parton distribution functions. Variants of HERAPDF2.0 with an alternative gluon parameterisation, HERAPDF2.0AG, and using fixed-flavour-number schemes, HERAPDF2.0FF, are presented. The analysis was extended by including HERA data on charm and jet production, resulting in the variant HERAPDF2.0Jets. The inclusion of jet-production cross sections made a simultaneous determination of these parton distributions and the strong coupling constant possible, resulting in $\alpha_s(M_Z)=0.1183 \pm 0.0009 {\rm(exp)} \pm 0.0005{\rm (model/parameterisation)} \pm 0.0012{\rm (hadronisation)} ^{+0.0037}_{-0.0030}{\rm (scale)}$. An extraction of $xF_3^{\gamma Z}$ and results on electroweak unification and scaling violations are also presented.

H1 and ZEUS have published single-differential cross sections for inclusive D ∗±-meson production in deep-inelastic ep scattering at HERA from their respective final data sets. These cross sections are combined in the common visible phase-space region of photon virtuality Q 2 > 5 GeV2, electron inelasticity 0.02 < y < 0.7 and the D ∗± meson’s transverse momentum p T(D ∗) > 1.5 GeV and pseudorapidity |η(D ∗)| < 1.5. The combination procedure takes into account all correlations, yielding significantly reduced experimental uncertainties. Double-differential cross sections d2 σ/dQ 2dy are combined with earlier D ∗± data, extending the kinematic range down to Q 2 > 1.5 GeV2. Perturbative next-to-leading-order QCD predictions are compared to the results., Journal of High Energy Physics, 2015 (9), ISSN:1126-6708, ISSN:1029-8479

Aims The background was to analyse the influence of hospital- and surgeon volume and of the extent of resective procedures on the quality of early and late treatment results in gastric cancer. Methods The literature was reviewed by searching the databases of Medline, Cancerlit, Pubmed and the Cochran register. Results The levels of evidence showed wide variations. The influence of hospital volume was more important for the outcome than the case load of the individual surgeon. The extent of surgical resection should be adapted to histology—or stage. The value of systematic lymph node dissection is still under discussion. Conclusions We have found that the best treatment results were seen in high volume hospitals with experienced surgeons, even taking into account extended surgical procedures. Further studies are needed to define the optimal number of operations necessary to be carried out each year.

F. Aharonian, A. Akhperjanian, M. Beilicke, K. Bernlohr, H.-G. Borst, H. Bojahr, O. Bolz, T. Coarasa, J. Contreras, J. Cortina, S. Denninghoff, V. Fonseca, M. Girma, N. Gotting, G. Heinzelmann, G. Hermann, A. Heusler, W. Hofmann, D. Horns, I. Jung, R. Kankanyan, M. Kestel, A. Kohnle, A. Konopelko, D. Kranich, H. Lampeit, M. Lopez, E. Lorenz, F. Lucarelli, O. Mang, D. Mazin, H. Meyer, R. Mirzoyan, A. Moralejo, E. Ona-Wilhelmi, M. Panter, A. Plyasheshnikov, G. Puhlhofer, R. de los Reyes, W. Rhode, J. Ripken, G. P. Rowell, V. Sahakian, M. Samorski, M. Schilling, M. Siems, D. Sobzynska, W. Stamm, M. Tluczykont, V. Vitale, H. J. Volk, C. A. Wiedner, and W. Wittek

The array of 5 imaging atmospheric y Cerenkov telescopes (IACTs) deployed at La Palma (Canary Islands), and operated by the HEGRA (High Energy Gamma Ray Astronomy) collaboration, was used for observations of the Monoceros Loop SNR region for a total of about 120 hrs and 20 hrs in ON-source and OFF-source mode, respectively. The giant molecular cloud Rosette Nebula appears in the sky region, close to the south-east part of the SNR rim. Using the HEGRA system of IACTs of rather large field of view (4.3 degree in diameter), we have mapped the extended sky region of 3 ◦ × 3 ◦ associated with the Monoceros SNR/Rosette Nebula, which is centered towards the hard spectrum X-ray point source SAX J0635+533. The EGRET unidentified source of diffuse γ-ray emission (3EG J0634+0521) observed in the energy range between 100 MeV-10 GeV, was effectively in the field of view of our present observations. Also, the GeV source GeV J0633+0645 was within the available field of view. The performance of the IACTs array reveals an energy threshold of 500 GeV and an angular resolution of 0.1 ◦ for γ-rays. In what follows, we present the result of the data analysis and its physical interpretation.