298 results on '"Ishizaki, Toshimasa"'
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2. A novel mRNA decay inhibitor abolishes pathophysiological cellular transition
3. Mechanism of action of non-camptothecin inhibitor Genz-644282 in topoisomerase I inhibition
4. Conditional deficiency of Rho‐associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice
5. The benzylisoquinoline alkaloids, berberine and coptisine, act against camptothecin-resistant topoisomerase I mutants
6. Caspase-4 has a role in cell division in epithelial cells through actin depolymerization
7. Analysis of Chromosomal DNA Fragmentation in Apoptosis by Pulsed-Field Gel Electrophoresis
8. ROCK-I Regulates Closure of the Eyelids and Ventral Body Wall by Inducing Assembly of Actomyosin Bundles
9. ROCK and mDia1 Antagonize in Rho-Dependent Rac Activation in Swiss 3T3 Fibroblasts
10. Focal Contacts as Mechanosensors: Externally Applied Local Mechanical Force Induces Growth of Focal Contacts by an mDia1-Dependent and ROCK-Independent Mechanism
11. Caspase-4 has a role in cell division in epithelial cells through actin depolymerization
12. Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase
13. Molecular Dissection of the Rho-Associated Protein Kinase (p160ROCK)-Regulated Neurite Remodeling in Neuroblastoma N1E-115 Cells
14. Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho
15. Molecular Structures, Cellular Functions, and Physiological Roles of Rho Effectors
16. Protective effect of hydrogen sulfide on pancreatic beta-cells
17. Rotational Movement of the Formin mDia1 Along the Double Helical Strand of an Actin Filament
18. The ROCK signaling regulates the pulmonary vascular permeability via maintenance of lung homeostasis.
19. Disruption of Actin Dynamics Regulated by Rho Effector mDia1 Attenuates Pressure Overload-Induced Hypertrophic Responses in Cardiac Ventricle and Exacerbates Dysfunction.
20. Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells
21. Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells
22. mDia2 Shuttles between the Nucleus and the Cytoplasm through the Importin-α/β- and CRM1-mediated Nuclear Transport Mechanism
23. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
24. Timosaponin Aiii Disrupts Morphological Plasticity and Migration of Breast Adenocarcinoma Through Inhibition of Integrin Internalisation
25. Timosaponin AIII disturbs morphological plasticity and migration by suppressing membrane dynamics.
26. Cdc42 and mDia3 regulate microtubule attachment to kinetochores
27. EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination
28. GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins
29. Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow
30. IRR is involved in glucose-induced endocytosis after insulin secretion
31. Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II
32. Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction
33. Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumour microenvironment.
34. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
35. p160ROCK mediates RhoA activation of Na–H exchange
36. p140mDia, a mammalian homolog of Drosophila diaphanous,is a target protein for Rho small GTPase and is a ligand for profilin
37. Role of citron kinase as a target of the small GTPase Rho in cytokinesis
38. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
39. Use and properties of ROCK-specific inhibitor Y-27632
40. GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion
41. Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction.
42. Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop
43. A Critical Role for a Rho-Associated Kinase, p160ROCK, in Determining Axon Outgrowth in Mammalian CNS Neurons
44. Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumor microenvironment
45. Transformation mediated by RhoA requires activity of ROCK kinases
46. Rhophilin, a small GTPase Rho-binding protein, is abundantly expressed in the mouse testis and localized in the principal piece of the sperm tail
47. A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors
48. Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes
49. Loss of a Rho-Regulated Actin Nucleator, mDia2, Impairs Cytokinesis during Mouse Fetal Erythropoiesis
50. GTP- and GDP-Dependent Rab27a Effectors in Pancreatic Beta-Cells
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