1. Influence of disease course and comprehensive management on blood glucose level in children and adolescents with type 2 diabetes mellitus
- Author
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Xiaozhi Wu, Rui Wang, Jiahui Chen, Guoshuang Feng, Xinyu Wang, Robin N Bai, Xuejun Liang, Bingyan Cao, Chunxiu Gong, Wenjing Li, Yanmei Sang, Xumei Wang, and Di Wu
- Subjects
Children ,Glycemic control ,Type 2 diabetes mellitus ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Abstract Aims/Introduction The aim of the present study was to evaluate the status of glycemic control, and assess the effects of the disease course and comprehensive management measures on the blood glucose level in children and adolescents with type 2 diabetes mellitus. Materials and Methods The study collected the clinical data of type 2 diabetes patients in Beijing Children's Hospital from January 2015 to September 2020. Patients were grouped based on the disease course to compare their glycated hemoglobin (HbA1c) level, islet β‐cell function, insulin resistance and comprehensive management measures. Results Of the 170 participants, the median disease course was 2.0 years (interquartile range [IQR] 1.0–4.0 years). The baseline HbA1c was 11.2% (IQR 9.2–12.4%). According to the grouping by the disease course, the median HbA1c was the lowest (5.7% [IQR 5.3–6.1%]) in the half‐year course group and the highest in the 4‐year course group (9.0 [IQR 6.8%–11.3%]). Compared with the group with a disease duration 4 years group had a lower proportion of patients with HbA1c
- Published
- 2024
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