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The aim of this study was to investigate and compare the effects of three herbal mixture extracts on obesity induced by high-fat diet (HFD) in rats. The prescriptions— Pericarpium citri reticulatae and Fructus crataegi —were used as matrix components and mixed with Ampelopsis grossedentata , Salvia miltiorrhiza , and epigallocatechin-3-gallate (EGCG) to form T1, T2, and T3 complexes, respectively. Results revealed that HFD feeding significantly increased body weight gain, fat deposition, plasma lipid profiles, hepatic lipid accumulation, and hepatic vacuoles formation, but decreased plasma levels of adiponectin in rats. Only the T1 complex showed the tendency, although not significantly so, for decreased HFD-induced body weight gain. T1 and T3 complexes significantly reduced HFD-induced fat deposition, and plasma levels of triglyceride, total cholesterol, and low-density lipoprotein cholesterol. Only the T1 complex significantly increased HFD-reduced adiponectin levels in plasma, but decreased HFD-increased triglyceride content in liver tissues. All complexes effectively inhibited HFD-induced vacuoles formation. The content of dihydromyricetin, salvianolic acid B, and EGCG in T1, T2, and T3 complexes was 18.25 ± 0.07%, 22.20 ± 0.10%, and 18.86 ± 0.04%, respectively. In summary, we demonstrated that herbal mixture extracts, especially T1 complex, exhibit antiobesity activity in HFD-fed rats.

With respect to the voltage distortion caused by harmonics and unbalanced loads, traditional digital phase lock algorithm doesn't work properly. And this paper presents a novel estimating algorithm based on BP neutral network model. The voltage signal is the input of the network and then by training the network with the prepared samples, the network can calculate the grid phase correctly. This algorithm has no relationship with the harmonics so it can work in a wide range. A network program is finished and the algorithm is validated. The results show that the algorithm works effectively and the result is correct.

With the development of our country socialist market economy as well as our country accession to the WTO, the construction market gradually opens, and the competition is day by day intense. It has brought the unprecedented opportunities and challenges for the engineering project management. There is therefore an urgent need to analyze the engineering project management model. The engineering project management model is one of the key factors to the successful engineering project, along with the development of society and continuing to develop. In view of this, this article first has carried on the contrast analysis to several kinds of commonly used engineering project management models, and then discusses Partnering model which has been successfully applied in recent years in the field of engineering in some European and American countries and Chinese Hong Kong. Finally, it analyzes the present situation of our country engineering project management, proposing the corresponding measures, with a view to contributing to the realization of our country engineering project optimization management.

Two new glycosides, 1,6-di-O-syringoyl-β-d-glucopyranose (1) and quercetin 3-O-[(3-O-syringoyl-α-l-rhamnopyranosyl)-(1 → 6)-β-d-glucopyranoside] (2), along with seven known compounds were isolated from the MeOH extract of Leonurus japonicus. The structures of these compounds were elucidated by spectral analysis.

Cuttlebone complex (CBC), a homology of medicine and food formula, is comprised of five herbal medicines (Endoconcha Sepiae, Radix Paeoniae Rubra, fresh ginger, Fructus Amomi, and Radix Glycyrrhizae) and two food ingredients (Zingiber zerumbet and chitosan). Herein, the gastroprotective potential against indomethacin and a safety assessment of CBC were investigated. In a gastroprotective model, CBC effectively decreased the indomethacin-increased gastric ulcerous lesions, and increased the indomethacin-decreased prostaglandin E2 levels in the gastric mucosa. In genotoxicity tests, CBC treatment did not increase the numbers of revertant colonies in five Salmonella typhimurium strains and chromosome aberrations in Chinese hamster ovary CHO-K1 cells, with or without S9 metabolic activation. The oral supplementation of CBC did not increase micronucleus formation in the peripheral blood of mice. In a subacute toxicity study, the body weight and blood biochemical parameters observed in CBC-treated rats were normal. In conclusion, CBC was considered as a non-toxic formula and could be used to remedy indomethacin-induced gastric damage.

Epithelioid angiomyolipoma is a recently described rare variant of renal angiomyolipoma. It can occur in patients with or without tuberous sclerosis. We report the imaging findings of a case of epithelioid angiomyolipoma that showed the presence of fatty tissue undifferentiated from the typical angiomyolipoma at the beginning. After partial nephrectomy, tumour recurrence occurred two years later, presenting as completely solid tumours with no adipose tissue, and with invasion into the psoas muscle and left adrenal gland. Differentiation of this tumour from renal cell carcinoma is difficult. Both the radiologist and surgeon should be aware of the existence of this tumour and its potentially malignant behaviour.

Five new homoisoflavonoids, ophiopogonanone C (1), ophiopogonanone D (2), ophiopogonone C (3), ophiopogonanone E (4) and ophiopogonanone F (5), and six known compounds were isolated from an ethanol extract of the tubers of Ophiopogon japonicus (Thunb) Ker-Gawl. Spectroscopic analyses were used to elucidate the structures of these compounds.