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In heterogeneous catalysis, the interface between active metal and support plays a key role in catalyzing various reactions. Specially, the synergistic effect between active metals and oxygen vacancies on support can greatly promote catalytic efficiency. However, the construction of high-density metal-vacancy synergistic sites on catalyst surface is very challenging. In this work, isolated Pt atoms are first deposited onto a very thin-layer of MoO

Jackhammer (hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are limited. We describe a 60-year-old man who presented with dysphagia, chest pain and heartburn for a period of 1 year. His workup showed Barrett's esophagus on endoscopy and high-resolution manometry demonstrated jackhammer esophagus with esophagogastric junction outflow obstruction. The patient was treated with proton pump inhibitor and nifedipine but without resolution of his symptoms. He was followed up to assess the efficacy of treatment with deanxit (flupentixol + melitracen). Dysphagia and chest pain resolved during the therapeutic trial and efficacy was maintained on maintenance treatment without troublesome side effects.

Injection of hyaluronic acid (HA) filler is a common aesthetic procedure. Impairment of vision, although rare, is a devastating complication of this procedure, which may not be reversible. We report on a patient who experienced visual acuity impairment and ischemic oculomotor nerve palsy after injection of HA into the nasal dorsum. In this case, clinical signs improved within 14 days of treatment. We also provide a review of the mechanism, clinical features, risk factors, and prevention and treatment strategies relating to embolization of ocular circulation after injection of HA. Vision loss is a rare but devastating complication of injection of hyaluronic acid (HA) in the face. Visual acuity seldom recovers completely. We report on a 22-year-old Asian woman who experienced obstruction of a branch of the retinal artery after injection of HA to augment her nose. The patient's visual acuity declined shortly after the procedure, and ophthalmoplegia occurred. Combination treatment was administered to restore the perfusion and oxygen supply to the retina and optic nerve. Within 14 days of rigorous treatment, the patient experienced improvement in visual acuity, extraocular movement, and visual field defects. LEVEL OF EVIDENCE 5: Risk.

We present a study aimed at developing a terahertz time domain spectroscopy (THz-TDS) system for detection of the optical properties of ex vivo rabbit corneal tissues with different water content at terahertz frequencies (0.1–0.3 THz). The refractive index decreased with frequency while the absorption coefficient increased with frequency. Our experimental results matched the theoretical calculation very well revealing that both the absorption coefficient and the refractive index of a hydrated cornea were much larger than that of a dehydrated cornea and the terahertz properties depended on the hydrate conditions of the biosamples.

Cysteinyl leukotriene receptor 1 (CYSLTR1) serves a pivotal role in allergic reactions, which is one of the main causes of adenoid hypertrophy. The present study aimed to investigate the function of CYSLT1 within adenoid hypertrophy. A total of 40 patients with adenoid hypertrophy were recruited between January 2014 and January 2016 at the Children's Hospital of Hebei Province, China. The patients were divided into either the mild-moderate group or the severe group according to their disease severity. The expression of CYSLT1 in the adenoid tissue and whole blood of all patients and healthy controls was detected by reverse transcription-quantitative polymerase chain reaction. Associations between the expression level of CYSLT1 and the clinical characteristics of patients were analyzed. Primary human adenoid epithelial cells (HAECs) with CYSLT1 knockdown and overexpression were constructed. The levels of extracellular signal-regulated kinase (ERK)2 and phosphorylated-ERK1/2 in adenoid tissue and HAECs were detected by western blot analysis. The expression of CYSLT1 in adenoid tissue and whole blood of all patients with adenoid hypertrophy was significantly higher compared with the healthy controls (P

Traffic flow video processing is an important direction of the development of intelligent transportation, Gaussian mixture background modeling is one of commonly algorithms to build background modeling that is widely used in image processing field. In order to analysis the algorithm comprehensively ,in this paper, it calculus on formula as well as tests and compares some traffic flow videos, the solution based on the K-means, EM parameters model are presented, it gets the mathematical meaning and evolution process of the algorithm clearly by calculating formulas to provide theoretical guidance for practical application; the traffic flow videos processing can get the treatment ability of this algorithm according to the different situation of videos, analyze the mixed Gauss background modeling for time migration, the light changing, moving object shadow processing ability. In this paper, the algorithm of mixed Gauss background modeling is analyzed from two aspects of theory and application.

In view of the present situation of new energy resources in China, the thesis thinks that new energy industry has great development potential. And new energy industry has the self-organizing characteristics, this paper analyzes the new energy industry since the organization structure, environment and evolution mechanism of the system and the self-organization ability and the effect of policy intervention mechanism analysis, through the analysis of new energy industry since the organization system, in view of the government and the new energy industry itself put forward different development countermeasures respectively, hope to be able to promote the sustainable development of the new energy industry in our country.

A method that use fuzzy inference theory to infer the functional structure model is presented. Is based on fuzzy inference theory of artificial intelligence area, analyze and study the measured data, then extract plant growth rule and growth function. When constructing functional structure that can reflect the impact of the environment, the influence of environment was taken into full account. The source and sink organs respond the surrounding virtual environment according to its inbuilt growth function, and produce, allocate and consume assimilates as well as update the L-grammar representing the plant structure, and at last produce the plant that adapt to present virtual environment. The simulation test result show that the model can accurately extract the growth rule, construct right growth function, and vividly reflect the impact of environment.

Through-diffusion method was conducted to investigate the diffusion behavior of 125 I in bentonite in present of organic matter, such as polyaminopolycarboxy- late EDTA, oxalic acid, hydrazine and humic acid HA. The effective diffusion coefficient De value and rock capacity factor a were (2.32.6) 9 10 -11 m 2 /s and 0.040-0.052, respectively. The small difference showed that iodine was preferentially associated with silicoaluminate mineral as an inorganic form. In present of HA, the Da value of 125 I was almost two orders of magnitude higher than that of HA and humic substances HS. The De and a derived from the experiments were used to simulate its diffusion in the designed bentonite obstacle of high-level radioactive waste repository and the results showed that 125 I can be transported from 30 to 50 cm thickness of bentonite to the far-field of repository in several years.

Due to the energy supply and demand imbalance and unreasonable energy consumption structure, China should vigorously develop renewable energy. Wind power is important choice. In the past decade, the China wind power industry has developed rapidly. By 2012, the total installed capacity of wind power in China is 75324.2MW. China has become the largest installer of wind power capacity in the world. However, the wind power in also facing many problems. In this paper, analyzes wind power industry’s internal and external environments to identify opportunities, threats, strengths and weaknesses. Finally, put forward an appropriate strategy to promote the healthy and orderly development of the wind power industry.

Through-diffusion and out-diffusion are good way to understand anion diffusion behavior in compacted bentonite. In the present work we investigated Re (VII) and Se (IV) diffusion behavior in 2000 kg/m3 compacted GMZ bentonite. The De values of Re (VII) and Se (IV) are 0.29 ± 0.02 and 0.77 ± 0.05× 10-11 m2/s. The result obtained from out-diffusion method was not agreed with predicted data due to the heterogeneous porosity distribution in clay boundaries and species changed when the diffusion occurred in GMZ bentonite. Comparing the Da values of Se, Tc and I in GMZ and Kunigel-F bentonites, it showed that Kunigel-F bentonite hindered the mobilities of anion more efficiently than GMZ bentonite because of the higher content of montmorillonite.

In this work, we obtained a highly rare three-dimensional Zn(II) MOF, namely [Zn2(BTC)2(L)][(Me2NH2)2]·DMF (BTC3 − = 1,3,5-benzenetricarboxylate, L = N1,N4-bis(pyridin-3-ylmethyl)cyclohexane-1,4-dicarboxamide), and Me2NH2 = dimethylamine cation) by solvo(hydro)thermal method. This polymer was characterized by single-crystal X-ray diffraction, thermogravimetry and solid-state luminescence analysis. The outstanding structural feature of it is (3, 4)-connected net with unprecedented (6 · 82)(6 · 85)(62 · 10)(62 · 83 · 10) topology and self-penetrating motif.

Polyaminopolycarboxylate EDTA with powerful metal-binding property, which often presents in low and intermediate-level waste, can enhance the radionuclide migration. The effect of EDTA on the diffusion behavior of 99TcO4 − and ReO4 − in Gaomiaozi (GMZ) bentonite was investigated by using through-diffusion method. For 99TcO4 − in present of EDTA, the D e values was (1.2 ± 0.1) × 10−11 m2/s, which was 4 times higher than that in absent of EDTA. It can be explained that the complexation between 99TcO4 − and EDTA might be formed. By contrast, the D e values of ReO4 − remained unchanged in present or absent of EDTA, indicating that ReO4 − could not complex with EDTA. However, the diffusion of ReO4 − could be increased in present of EDTA, the D a value was found to be increased from 1.8 × 10−10 to 5.4 × 10−10 m2/s. It demonstrated that ReO4 − need more drastic conditions to form the Re(VII)–EDTA complexes than those used for 99TcO4 −. For both ReO4 − and 99TcO4 −, the rock capacity factor α is less than the total porosity e tot, indicating that they has little retention/sorption on the surface of bentonite.

OBJECTIVE: To establish normal reference values of induced sputum cytology in healthy children in southern China. METHODS: During a period from January 2010 to December 2011, a total of 580 healthy children (5–16 years of age) were approached. A total of 266 children (137 boys and 129 girls) participated in the study. Sputum induction was carried out by using 5% hypertonic saline. Cell types in the sputum were examined by using routine methods. RESULTS: Sputum induction was completed in 175 of the 266 subjects (65.79%), but 16 sputum samples were disqualified. The overall success rate was 59.77% (159/266). Macrophages and neutrophils were the predominant cell types: macrophages: median, 76.14%; interquartile range (IQR), 32.68%; and 2.5% to 97.5% percentile, 1.00% to 94.50%; neutrophils: median, 20.67%; IQR, 33.0%; and 2.5% to 97.5% percentile, 4.00% to 92.75%; eosinophils: median, 0.39%; IQR, 1.93%; and 2.5% to 97.5% percentile, 0.00% to 6.50%; and lymphocytes: median, 1.22%; IQR, 2.04%; and 2.5% to 97.5% percentile, 0.00% to 5.00%. The cell types did not differ among different age, gender, and passive smoking groups. Adverse events occurred in 4.4% (7/159) of the participants who completed the procedures but required no specific treatment to dissipate. Peak expiratory flow did not differ between those who completed the procedures compared with those who did not, suggesting that the procedure is safe and feasible in children. CONCLUSIONS: The current study represents the first attempt to develop normal reference values of induced sputum cytology in Chinese children, and could be used as a control for future studies.

OBJECTIVE: To investigate the distribution of respiratory viruses on throat swabs in hospitalized children with acute lower respiratory tract infection (ALRTI). METHODS: A total of 5 150 children with ALRTI who were admitted to Hebei Children's Hospital between March 2014 and February 2015 were enrolled to investigate the distribution of respiratory viruses in children with ALRTI. Direct immunofluorescence assay was performed for throat swabs from these children to detect influenza virus A (FA), influenza virus B (FB), adenovirus (ADV), respiratory syncytial virus (RSV), and parainfluenza virus types 1, 2, and 3 (PIV-1, PIV-2, and PIV-3). RESULTS: Of all the 5 150 throat swabs from hospitalized children, 2 155 (41.84%) had positive virus detection results. RSV had the highest detection rate (1 338 cases/25.98%), followed by PIV-3 (439 cases/8.52%) and FA (166 cases/3.22%), and 29 patients had mixed infection with 2 viruses. With the increasing age, the detection rates of viruses tended to decrease (χ(2)=279.623; P < 0.01). The positive rate of RSV increased gradually from September, and reached the peak value (60.09%) in November; the lowest positive rate occurred in June (1.51%). The positive rate of PIV-3 was the highest in May (21.38%) and the lowest in November (1.77%). CONCLUSIONS: The distribution of viruses in children with ALRTI varies with age and season, with RSV prevalence in autumn and winter and PIV-3 prevalence in spring and summer. RSV is the most common viral pathogen that causes ALRTI in hospitalized children.

With economy growth and industrialization, resources and environmental issues become seriously increasingly. People argue about that economy growth is whether the reason for environmental issues or the dynamic of resolving environmental issues. This argue give rise to the research upsurge of the relation of environment and economy. Environmental Kuznets Curve (EKC) hypothesis is the most typical among those. EKC is applied to analyze the relationship between economic growth and the changes of environment quality, it aims to provide a scientific reference for the decision-making policies of relevant department.

Power industry is the key field of implementing energy saving and pollutant emission reduction in china, strengthen power energy saving is helpful to establish a resource-saving and environment-friendly society and promote a sustainable development of economic society. This paper synchronizes respective advantages of rough set and neural network, puts forward a prediction model-RSBPNN which uses rough set knowledge reduction method to prune the redundant and neural network to build a forecasting model.

Environmental performance evaluation is a multi-attribute evaluation problem. The determination of indicators’ weight is the key problem in the multi-attributes evaluation. This paper set up an evaluation model based on multi-attribute variable coefficients and fuzzy pattern recognition aimed at a thermal power plant. The model gives full play to the advantages of the subjective and the objective coefficients and enables itself to alter the coefficients in accordance with the specific indicator values of evaluated objects, hence, bringing the function of performance evaluation into full play.

To improve the implementation efficiency of environmental policies, the paper put forward a dynamic supervision method based on Markov chain and fuzzy control. With Markov chain the enterprises’ Emission behavior can be forecasted. And with fuzzy control model, analyze the current emissions behavior and the recent changes in the emissions records. Combined the two results, Supervisors decide their dynamic environment supervision track. The sample analyses show that the method is practical.

Rationale Primary gastrointestinal mantle cell lymphoma is rare, and histopathological examination and specific immunohistochemical staining are still the gold standard for diagnosis. Therefore, it is necessary to find a new way to improve positive biopsy rates. Patient concerns A 58-year-old man was admitted to our hospital with epigastric pain, abdominal distension, nausea, and melena. Endoscopy identified submucosal neoplasms and diffuse gastrointestinal tract involvement including the esophagus. Diagnoses A false-negative diagnosis was first determined by ordinary endoscopy. However, a large tissue biopsy was subsequently performed using endoscopic mucosal resection based on endoscopic ultrasonography (EUS). Pathological examination of the biopsy specimens taken from the lesions of the duodenum and rectum revealed diffuse lymphocytic proliferation and obscure nodular and small cleaved cells with irregularly shaped nuclei. Immunohistochemistry showed that the cells were positive for CyclinD1, BCL-2, CD20, CD21, and CD5; however, they were negative for CD3, CD6, CD10, and CD43. Interventions The patient refused to receive further treatment. Outcomes Mantle cell lymphoma was conclusively diagnosed. Conclusions EUS has an important role in the diagnosis and management of gastrointestinal submucosal tumors. Performing a pathological biopsy including EUS may be useful for identifying the unknown nature of tumors of the digestive tract.

To examine fractional exhaled nitric oxide (FeNO) values in 1-3-year-old children with asthma and analyze the correlation of FeNO with peripheral blood eosinophils (EOS) and lung function in these children.A total of 111 children aged 1-3 years with asthma were enrolled. The children were classified into acute exacerbation (n=62) and remission groups (n=49) according to their symptoms. FeNO values, lung function, and peripheral blood EOS count were measured in these children. Sixty age-matched healthy children were enrolled as the control group.FeNO values were significantly higher in the acute exacerbation group (24.4 ppb) than in the remission group (18.0 ppb) and the control group (13.7 ppb) (P0.05). The FeNO values in the remission group were significantly higher than in the control group (P0.05). FeNO values were not significantly correlated with peripheral blood EOS count and lung function parameters (PEF, TEF25, TEF50, and TEF75).Measurement of FeNO is useful to evaluate the disease activity in children with asthma aged 1 to 3 years, but the FeNO values are not correlated with peripheral blood EOS count and lung function.

Tetrandrine (Tet), a bisbenzylisoquinoline alkaloid, has been reported to possess anti-tumour activity. However, its effects on human glioma remain unknown. In this study, we demonstrated that Tet inhibited human glioma cell growth in vitro and in vivo. It has been hypothesised that Tet inhibits glioma growth by affecting glioma cell survival, proliferation and vasculature in and around the xenograft tumour in the chick CAM model and signal transducer and activator of transcription 3 (STAT3) mediated these activities. Therefore, we conducted a detailed analysis of the inhibitory effects of Tet on cell survival using a TUNEL assay and flow cytometric analysis; on cell proliferation based on the expression of proliferating cell nuclear antigen; and on angiogenesis using a CAM anti-angiogenesis assay. We used western blotting to investigate the role of STAT3 on the anti-glioma activities of Tet. The results revealed that Tet inhibited survival and proliferation in human glioma cells, impaired tumour angiogenesis and decreased the expression of phosphorylated STAT3 and its downstream proteins. In sum, our data indicate that STAT3 is involved in Tet-induced the regression of glioma growth by activating tumour cell apoptosis, inhibiting glioma cell proliferation and inhibiting angiogenesis.

To study the utility of fractional exhaled nitric oxide (FeNO) in young children at different stages of asthma.Fifty-eight children with newly diagnosed asthma (aged 1-3 years) at the acute exacerbation stage between April and June, 2014 were recruited. After 3 months' treatment, the children switched into the chronic persistent stage (n=34) or remission stage (n=24). Thirty aged-matched healthy children served as controls. FeNO levels and lung function were measured for all subjects. The best cut-off value of FeNO for the diagnosis of asthma was evaluated by receiver operating characteristic (ROC) curve.The FeNO levels in children with asthma at various stages were higher than controls (P0.05). The FeNO levels in the acute exacerbation stage were highest, followed by the chronic persistent stage (P0.05). FeNO level was correlated to the stages of asthma (r=-0.382, P0.001). The cut-off value of FeNO for the diagnosis of asthma was 22.75 ppb by ROC curve, with the sensitivity of 0.933 and the specificity of 0.388.The children with asthma at different stages have different FeNO levels. Measurement of FeNO is useful in the diagnosis of asthma in young children.

This paper presents the key issues for high precision pointing system using Risley prism. An iterative optimization algorithm is proposed to solve the inverse problem of Risley Prism and anti-achromatic Risley Prism. Different error sources, particularly Risley prism's rotation errors and rotation axis jitters are considered. Error propagation formula between pointing accuracy and rotation position is deduced. Finally, a beam steering simulation system including target position creating module, Risley Prism inverse solution module, Risley Prism rotation control module and beam pointing module is established. The simulation results show that it can achieve better than 1 arcsec pointing accuracy.

Selenadiazole derivatives are synthetic organoselenium compounds with improved anticancer activity and greater selectivity than inorganic selenium. In this study, 4-(benzo[c][1,2,5]selenadiazol-6-yl)-benzene-1,2-diamine (BSBD) was shown to induce time- and dose-dependent apoptosis in SWO-38 human glioma cells by accumulation of a sub-G1 cell population, DNA fragmentation, nuclear condensation, caspase activation and poly(ADP-ribose) polymerase (PARP) cleavage. Further mechanistic investigation showed that BSBD treatment induced dephosphorylation of AKT and DNA damage-mediated activation of p53, leading to extensive apoptosis through the mitochondrial pathway. Our findings suggest that BSBD represents a potential human glioma therapeutic.