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2. Universal coupling between the photonics and phononics in a 3D graphene sponge

Author

Shalaby, M., Vicario, C., Giorgianni, F., Gaspar, M. A., Craievich, P., Chen, Y., Kan, B., Lupi, S., and Hauri, C. P.

Subjects
Physics - Applied Physics, Condensed Matter - Materials Science
Abstract

Photon-phonon coupling holds strong potential for sound and temperature control with light, opening new horizons in detector technology, remote sound generation and signal broadcasting. Here, we report on a novel stereoscopic ultralight converter based on a three dimensional graphene structure 3G-sponge, which exhibits very high absorption, near-to-air density, low inertia, and negligible effective heat capacity. We studied the heat and sound generation under the excitation of electromagnetic waves. 3G-sponge shows exceptional photon to heat and sound transduction efficiency over an enormous frequency range from MHz to PHz. As an application, we present an audio receiver based on a 3G-sponge amplitude demodulation. Our results will lead to a wide range of applications from light-controlled sound sources to broadband high-frequency graphene electronics.

Published
2019

3. JUNO Conceptual Design Report

Author

Adam, T., An, F., An, G., An, Q., Anfimov, N., Antonelli, V., Baccolo, G., Baldoncini, M., Baussan, E., Bellato, M., Bezrukov, L., Bick, D., Blyth, S., Boarin, S., Brigatti, A., Brugière, T., Brugnera, R., Avanzini, M. Buizza, Busto, J., Cabrera, A., Cai, H., Cai, X., Cammi, A., Cao, D., Cao, G., Cao, J., Chang, J., Chang, Y., Chen, M., Chen, P., Chen, Q., Chen, S., Chen, X., Chen, Y., Cheng, Y., Chiesa, D., Chukanov, A., Clemenza, M., Clerbaux, B., D'Angelo, D., de Kerret, H., Deng, Z., Ding, X., Ding, Y., Djurcic, Z., Dmitrievsky, S., Dolgareva, M., Dornic, D., Doroshkevich, E., Dracos, M., Drapier, O., Dusini, S., Díaz, M. A., Enqvist, T., Fan, D., Fang, C., Fang, J., Fang, X., Favart, L., Fedoseev, D., Fiorentini, G., Ford, R., Formozov, A., Gaigher, R., Gan, H., Garfagnini, A., Gaudiot, G., Genster, C., Giammarchi, M., Giuliani, F., Gonchar, M., Gong, G., Gong, H., Gonin, M., Gornushkin, Y., Grassi, M., Grewing, C., Gromov, V., Gu, M., Guan, M., Guarino, V., Guo, W., Guo, X., Guo, Y., Göger-Neff, M., Hackspacher, P., Hagner, C., Han, R., Han, Z., Hao, J., He, M., Hellgartner, D., Heng, Y., Hong, D., Hou, S., Hsiung, Y., Hu, B., Hu, J., Hu, S., Hu, T., Hu, W., Huang, H., Huang, X., Huo, L., Huo, W., Ioannisian, A., Ioannisyan, D., Jeitler, M., Jen, K., Jetter, S., Ji, X., Jian, S., Jiang, D., Jiang, X., Jollet, C., Kaiser, M., Kan, B., Kang, L., Karagounis, M., Kazarian, N., Kettell, S., Korablev, D., Krasnoperov, A., Krokhaleva, S., Krumshteyn, Z., Kruth, A., Kuusiniemi, P., Lachenmaier, T., Lei, L., Lei, R., Lei, X., Leitner, R., Lenz, F., Li, C., Li, F., Li, J., Li, N., Li, S., Li, T., Li, W., Li, X., Li, Y., Li, Z., Liang, H., Liang, J., Licciardi, M., Lin, G., Lin, S., Lin, T., Lin, Y., Lippi, I., Liu, G., Liu, H., Liu, J., Liu, Q., Liu, S., Liu, Y., Lombardi, P., Long, Y., Lorenz, S., Lu, C., Lu, F., Lu, H., Lu, J., Lubsandorzhiev, B., Lubsandorzhiev, S., Ludhova, L., Luo, F., Luo, S., Lv, Z., Lyashuk, V., Ma, Q., Ma, S., Ma, X., Malyshkin, Y., Mantovani, F., Mao, Y., Mari, S., Mayilyan, D., McDonough, W., Meng, G., Meregaglia, A., Meroni, E., Mezzetto, M., Min, J., Miramonti, L., Montuschi, M., Morozov, N., Mueller, T., Muralidharan, P., Nastasi, M., Naumov, D., Naumova, E., Nemchenok, I., Ning, Z., Nunokawa, H., Oberauer, L., Ochoa-Ricoux, J. P., Olshevskiy, A., Ortica, F., Pan, H., Paoloni, A., Parkalian, N., Parmeggiano, S., Pec, V., Pelliccia, N., Peng, H., Poussot, P., Pozzi, S., Previtali, E., Prummer, S., Qi, F., Qi, M., Qian, S., Qian, X., Qiao, H., Qin, Z., Ranucci, G., Re, A., Ren, B., Ren, J., Rezinko, T., Ricci, B., Robens, M., Romani, A., Roskovec, B., Ruan, X., Rybnikov, A., Sadovsky, A., Saggese, P., Salamanna, G., Sawatzki, J., Schuler, J., Selyunin, A., Shi, G., Shi, J., Shi, Y., Sinev, V., Sirignano, C., Sisti, M., Smirnov, O., Soiron, M., Stahl, A., Stanco, L., Steinmann, J., Strati, V., Sun, G., Sun, X., Sun, Y., Taichenachev, D., Tang, J., Tietzsch, A., Tkachev, I., Trzaska, W. H., Tung, Y., van Waasen, S., Volpe, C., Vorobel, V., Votano, L., Wang, C., Wang, G., Wang, H., Wang, M., Wang, R., Wang, S., Wang, W., Wang, Y., Wang, Z., Wei, W., Wei, Y., Weifels, M., Wen, L., Wen, Y., Wiebusch, C., Wipperfurth, S., Wong, S. C., Wonsak, B., Wu, C., Wu, Q., Wu, Z., Wurm, M., Wurtz, J., Xi, Y., Xia, D., Xia, J., Xiao, M., Xie, Y., Xu, J., Xu, L., Xu, Y., Yan, B., Yan, X., Yang, C., Yang, H., Yang, L., Yang, M., Yang, Y., Yanovich, E., Yao, Y., Ye, M., Ye, X., Yegin, U., Yermia, F., You, Z., Yu, B., Yu, C., Yu, G., Yu, Z., Yuan, Y., Yuan, Z., Zanetti, M., Zeng, P., Zeng, S., Zeng, T., Zhan, L., Zhang, C., Zhang, F., Zhang, G., Zhang, H., Zhang, J., Zhang, K., Zhang, P., Zhang, Q., Zhang, T., Zhang, X., Zhang, Y., Zhang, Z., Zhao, J., Zhao, M., Zhao, T., Zhao, Y., Zheng, H., Zheng, M., Zheng, X., Zheng, Y., Zhong, W., Zhou, G., Zhou, J., Zhou, L., Zhou, N., Zhou, R., Zhou, S., Zhou, W., Zhou, X., Zhou, Y., Zhu, H., Zhu, K., Zhuang, H., Zong, L., and Zou, J.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The Jiangmen Underground Neutrino Observatory (JUNO) is proposed to determine the neutrino mass hierarchy using an underground liquid scintillator detector. It is located 53 km away from both Yangjiang and Taishan Nuclear Power Plants in Guangdong, China. The experimental hall, spanning more than 50 meters, is under a granite mountain of over 700 m overburden. Within six years of running, the detection of reactor antineutrinos can resolve the neutrino mass hierarchy at a confidence level of 3-4$\sigma$, and determine neutrino oscillation parameters $\sin^2\theta_{12}$, $\Delta m^2_{21}$, and $|\Delta m^2_{ee}|$ to an accuracy of better than 1%. The JUNO detector can be also used to study terrestrial and extra-terrestrial neutrinos and new physics beyond the Standard Model. The central detector contains 20,000 tons liquid scintillator with an acrylic sphere of 35 m in diameter. $\sim$17,000 508-mm diameter PMTs with high quantum efficiency provide $\sim$75% optical coverage. The current choice of the liquid scintillator is: linear alkyl benzene (LAB) as the solvent, plus PPO as the scintillation fluor and a wavelength-shifter (Bis-MSB). The number of detected photoelectrons per MeV is larger than 1,100 and the energy resolution is expected to be 3% at 1 MeV. The calibration system is designed to deploy multiple sources to cover the entire energy range of reactor antineutrinos, and to achieve a full-volume position coverage inside the detector. The veto system is used for muon detection, muon induced background study and reduction. It consists of a Water Cherenkov detector and a Top Tracker system. The readout system, the detector control system and the offline system insure efficient and stable data acquisition and processing., Comment: 328 pages, 211 figures

Published
2015

10. Word Sense Disambiguation with Knowledge-Enhanced and Local Self-Attention-based Extractive Sense Comprehension

Author

Zhang, G, Lu, W, Peng, X, Wang, S, Kan, B, Yu, R, Zhang, G, Lu, W, Peng, X, Wang, S, Kan, B, and Yu, R

Abstract

Word sense disambiguation (WSD), identifying the most suitable meaning of ambiguous words in the given contexts according to a predefined sense inventory, is one of the most classical and challenging tasks in natural language processing. Reformulating WSD as a text span extraction task is an effective approach, which accepts a sentence context of an ambiguous word together with all definitions of its candidate senses simultaneously, and requires to extract the text span corresponding with the right sense. However, the approach merely depends on a short definition to learn sense representation, which neglects abundant semantic knowledge from related senses and leads to data-inefficient learning and suboptimal WSD performance. To address the limitations, we propose a novel WSD method with Knowledge-Enhanced and Local self-attention-based Extractive Sense Comprehension (KELESC). Specifically, a knowledge-enhanced method is proposed to enrich semantic representation by incorporating additional examples and definitions of the related senses in WordNet. Then, in order to avoid the huge computing complexity induced by the additional information, a local self-attention mechanism is utilized to constrain attention to be local, which allows longer input texts without large-scale computing burdens. Extensive experimental results demonstrate that KELESC achieves better performance than baseline models on public benchmark datasets.

Published
2022

11. Word Sense Disambiguation Based on Memory Enhancement Mechanism

Author

Kan, B, Lu, W, Peng, X, Wang, S, Zhang, G, Zhang, W, Qiao, X, Kan, B, Lu, W, Peng, X, Wang, S, Zhang, G, Zhang, W, and Qiao, X

Abstract

Word sense disambiguation (WSD) is a very critical yet challenging task in natural language processing (NLP), which aims at identifying the most suitable meaning of ambiguous words in the given contexts according to a predefined sense inventory. Existing WSD methods usually focus on learning the semantic interactions between a special ambiguous word and the glosses of its candidate senses and thus ignore complicated relations between the neighboring ambiguous words and their glosses, leading to insufficient learning of the interactions between words in context. As a result, they are difficult to leverage the knowledge from the other ambiguous words which might provide some explicit clues to identify the meaning of current ambiguous word. To mitigate this challenge, this paper proposes a novel neural model based on memory enhancement mechanism for WSD task, which stores the gloss knowledge of previously identified words into a memory, and further utilizes it to assist the disambiguation of the next target word. Extensive experiments, which are conducted on a unified evaluation framework of the WSD task, demonstrate that our model achieves better disambiguation performance than the state-of-the-art approaches (Code: https://github.com/baoshuo/WSD ).

Published
2022

25. Correction: Efficient non-fullerene organic solar cells employing sequentially deposited donor-acceptor layers (Journal of Materials Chemistry A (2018) 6 (18225–18233) DOI: 10.1039/C8TA06860G)

Author

Zhang, J, Kan, B, Pearson, AJ, Parnell, AJ, Cooper, JFK, Liu, XK, Conaghan, PJ, Hopper, TR, Wu, Y, Wan, X, Gao, F, Greenham, NC, Bakulin, AA, Chen, Y, Friend, RH, Zhang, Jiangbin [0000-0001-6565-5962], Conaghan, Patrick [0000-0001-9199-5805], Wu, Yutian [0000-0002-1552-1568], Greenham, Neil [0000-0002-2155-2432], Friend, Richard [0000-0001-6565-6308], and Apollo - University of Cambridge Repository

Subjects
3403 Macromolecular and Materials Chemistry, 34 Chemical Sciences, 4016 Materials Engineering, 40 Engineering
Abstract

Correction for ‘Efficient non-fullerene organic solar cells employing sequentially deposited donor–acceptor layers’ by Jiangbin Zhang et al., J. Mater. Chem. A, 2018, 6, 18225–18233.

Published
2018
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26. Bonding Performance and Microstructural Mechanism between Rapid Repair Materials and Old Concrete Pavement

Author

Kan Bao, Gaowang Zhang, Jiangpeng Lv, Junmin Li, Zexin Chen, and Jie Yuan

Subjects
rapid repair material, cement mortar, bonding performance, interfacial transition zone, microstructure, Building construction, TH1-9745
Abstract

In China, airports predominantly utilize airport cement concrete pavement, which inevitably undergoes deterioration in service. To uphold pavement durability and functionality, and ensure aircraft operational safety, prompt repairs of affected areas are imperative. Therefore, ordinary Portland cement mortars were used as the control group to compare and analyze the bonding performances of two common airport pavement repair materials: modified Portland cement mortars and phosphate cement mortars. Meanwhile, through microscopic experiments, the microscopic characteristics of the interfacial transition zone (ITZ) were studied, and the interface bonding mechanism was analyzed. The research results indicate that the interface bonding strength between phosphate cement mortar and old concrete pavement is the highest. This was because the elements in phosphate cement penetrated the old concrete pavement through hydration reactions, forming van der Waals forces and chemical bonding forces. In addition, the research results indicated that the presence of old concrete pavement made the three repair materials produce similar sidewall effects with the old concrete pavement, leading to a low hydration degree of the repair materials. However, the chemical bonding and penetrating structure of phosphate cement compensated for the weakening effect of the ITZ in the repair materials.

Published
2024
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27. The effect of CDP-choline on autophagy and mitochondrial dynamics in beta-amyloid treated PC12 cells

Author

Bilge, B., Gezmis, H., Bozkurt, S., Yucel, D., Kan, B., Ulus, I. H., Oz-Arslan, D., Bilge, B, Gezmis, H, Bozkurt, S, Yucel, D, Kan, B, Ulus, IH, Oz-Arslan, D, and Yeditepe Üniversitesi

Abstract

… Int Union Pure & Appl Biophys, European Biophys Soc Assoc, Inst Phys, Biol Phys Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [114Z494] This work was supported by The Scientific and Technological Research Council of Turkey (Grant number: 114Z494).

Published
2017

37. Characterization of the USDA Cucurbita pepo, C. moschata, and C. maxima germplasm collections

Author

Christopher O. Hernandez, Joanne Labate, Kathleen Reitsma, Jack Fabrizio, Kan Bao, Zhangjun Fei, Rebecca Grumet, and Michael Mazourek

Subjects
germplasm, genotyping-by-sequencing, GWAS, diversity, Cucurbita, Plant culture, SB1-1110
Abstract

The Cucurbita genus is home to a number of economically and culturally important species. We present the analysis of genotype data generated through genotyping-by-sequencing of the USDA germplasm collections of Cucurbita pepo, C. moschata, and C. maxima. These collections include a mixture of wild, landrace, and cultivated specimens from all over the world. Roughly 1,500 - 32,000 high-quality single nucleotide polymorphisms (SNPs) were called in each of the collections, which ranged in size from 314 to 829 accessions. Genomic analyses were conducted to characterize the diversity in each of the species. Analysis revealed extensive structure corresponding to a combination of geographical origin and morphotype/market class. Genome-wide associate studies (GWAS) were conducted using both historical and contemporary data. Signals were observed for several traits, but the strongest was for the bush (Bu) gene in C. pepo. Analysis of genomic heritability, together with population structure and GWAS results, was used to demonstrate a close alignment of seed size in C. pepo, maturity in C. moschata, and plant habit in C. maxima with genetic subgroups. These data represent a large, valuable collection of sequenced Cucurbita that can be used to direct the maintenance of genetic diversity, for developing breeding resources, and to help prioritize whole-genome re-sequencing.

Published
2023
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39. Clinical characteristics, virulence factors and molecular typing of methicillin-resistantStaphylococcus aureusinfections in Shenzhen City, China

Author

HU, L., primary, LI, Y., additional, LU, Y., additional, KLENA, J. D., additional, QIU, Y., additional, LIN, Y., additional, JIANG, M., additional, SHI, X., additional, CHEN, L., additional, LIU, X., additional, MA, H., additional, CHENG, J., additional, WU, S., additional, KAN, B., additional, and HU, Q., additional

Published
2016
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42. Comparison of automated ribotyping and pulsed-field gel electrophoresis for subtyping of Vibrio cholerae

Author

Kan B, Li Zhang, Bo Pang, Baowei Diao, Zhigang Cui, and Haijian Zhou

Subjects
Serotype, Outbreak, Biology, medicine.disease_cause, biology.organism_classification, medicine.disease, Applied Microbiology and Biotechnology, Cholera, Ribotyping, Subtyping, Microbiology, Bacterial Typing Techniques, Electrophoresis, Gel, Pulsed-Field, Vibrio cholerae, Vibrionaceae, medicine, Pulsed-field gel electrophoresis, Humans
Abstract

Aims: To compare the discriminatory power of an automated ribotyping method for Vibrio cholerae subtyping with the pulsed-field gel electrophoresis (PFGE), to evaluate the possibility of automated ribotyping in use of outbreak investigations and surveillance of cholera. Methods and Results: Eight-one epidemiologically unrelated isolates of V. cholerae, and 19 isolates from seven cholera outbreaks were used as the panels. When comparing the two methods using the epidemiologically unrelated isolates, automated ribotyping using PvuII distinguished 38 different ribotypes with a D-value of 0·8956. When combined with serotyping, the D-value is 0·9466. However, PFGE with NotI and SfiI digestions had higher D-values of 0·9951 and 0·9948, respectively. PFGE could cluster the isolates from each outbreak into the same pattern, and distinguish different patterns from different outbreaks, whereas automated ribotyping had lower discriminatory ability. Conclusions: The automated ribotyping has lower discriminatory ability compared to PFGE, and is limited to application in V. cholerae subtyping and outbreak investigation. Significance and Impact of the Study: The study evaluated the limitation in subtyping of automated ribotyping for V. cholerae, and raise the question of improvement for the automated ribotyping in subtyping.

Published
2009

44. Hypertension, BMI, and cardiovascular and cerebrovascular diseases

Author

Qiao Wenjing, Zhang Xinyi, Kan Bo, Vuong Ann M., Xue Shanshan, Zhang Yuzheng, Li Binbin, Zhao Qianqian, Guo Dingjie, Shen Xue, and Yang Shuman

Subjects
cardiovascular and cerebrovascular diseases, body mass index, hypertension, Medicine
Abstract

Hypertension is associated with body mass index (BMI) and cardiovascular and cerebrovascular diseases (CCDs). Whether hypertension modifies the relationship between BMI and CCDs is still unclear. We examined the association between BMI and CCDs and tested whether effect measure modification was present by hypertension. We identified a population-based sample of 3,942 participants in Shuncheng, Fushun, Liaoning, China. Hypertension was defined as any past use of antihypertensive medication or having a measured systolic/diastolic blood pressure ≥130/80 mm Hg. BMI was calculated from measured body weight and body height. Data on diagnosed CCDs were self-reported and validated in the medical records. We used logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations between BMI and CCDs. Higher BMI was associated with increased odds of having CCDs (OR = 1.19, 95% CI: 1.07–1.31). This association was significantly modified by hypertension (P for interaction 0.10). Although higher BMI was associated with increased odds of CCDs, the relationship was mainly limited to hypertensive patients.

Published
2021
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46. Structural characterization of T-protein of the Escherichia coli glycine cleavage system by X-ray small angle scattering

Author

Orun O, Mh, Koch, Kan B, Dmitri Svergun, Mv, Petoukhov, and Sayers Z

Subjects
Hydroxymethyl and Formyl Transferases, Models, Molecular, Chromatography, Escherichia coli Proteins, X-Rays, Escherichia coli, Aminomethyltransferase, Scattering, Radiation, Protein Structure, Tertiary
Abstract

T-protein, one of the components of the glycine cleavage complex, catalyses the formation of ammonia and methylene-tetrahydrofolate from H-protein-bound intermediate. Native T-protein of the glycine cleavage system from E. coli was efficiently purified using a combination of hydrophobic interaction, gel permeation and ion exchange chromatography. Synchrotron radiation small angle X-ray solution scattering indicates that T-protein has an extended structure in solution. A low resolution model of the protein was constructed ab initio and tentative models of the tertiary structure were built using prediction methods constrained by the scattering data.

Published
2004

49. LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? A TBNET consensus statement

Author

Mack, U, Migliori, G B, Sester, M, Rieder, H L, Ehlers, S, Goletti, D, Bossink, A, Magdorf, K, Hölscher, C, Kampmann, B, Arend, S M, Detjen, A, Bothamley, G, Zellweger, J P, Milburn, H, Diel, R, Ravn, P, Cobelens, F, Cardona, P J, Kan, B, Solovic, I, Duarte, R, Cirillo, D M, Mack, U, Migliori, G B, Sester, M, Rieder, H L, Ehlers, S, Goletti, D, Bossink, A, Magdorf, K, Hölscher, C, Kampmann, B, Arend, S M, Detjen, A, Bothamley, G, Zellweger, J P, Milburn, H, Diel, R, Ravn, P, Cobelens, F, Cardona, P J, Kan, B, Solovic, I, Duarte, R, and Cirillo, D M

Abstract

Udgivelsesdato: 2009-May, Tuberculosis control relies on the identification and preventive treatment of individuals who are latently infected with Mycobacterium tuberculosis. However, direct identification of latent tuberculosis infection is not possible. The diagnostic tests used to identify individuals latently infected with M. tuberculosis, the in vivo tuberculin skin test and the ex vivo interferon-gamma release assays (IGRAs), are designed to identify an adaptive immune response against, but not necessarily a latent infection with, M. tuberculosis. The proportion of individuals who truly remain infected with M. tuberculosis after tuberculin skin test or IGRA conversion is unknown. It is also uncertain how long adaptive immune responses towards mycobacterial antigens persist in the absence of live mycobacteria. Clinical management and public healthcare policies for preventive chemotherapy against tuberculosis could be improved, if we were to gain a better understanding on M. tuberculosis latency and reactivation. This statement by the TBNET summarises knowledge and limitations of the currently available tests used in adults and children for the diagnosis of latent tuberculosis infection. In summary, the main issue regarding testing is to restrict it to those who are known to be at higher risk of developing tuberculosis and who are willing to accept preventive chemotherapy.

Published
2009

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