2,177 results on '"Karim, R"'
Search Results
2. Characteristics and 6-Month Outcomes in Patients with Rheumatoid Arthritis Initiating Infliximab Biosimilar IFX-dyyb in a Real-World Setting
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Baker, Joshua F., Bakewell, Catherine, Dikranian, Ara, Lam, Gordon, O’Brien, Jacqueline, Moore, Page C., Yu, Miao, Hur, Peter, and Masri, Karim R.
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- 2024
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3. Identifying physical structures in our Galaxy with Gaussian Mixture Models: An unsupervised machine learning technique
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Tiwari, M., Kievit, R., Kabanovic, S., Bonne, L., Falasca, F., Guevara, C., Higgins, R., Justen, M., Karim, R., Kavak, Ü., Pabst, C., Pound, M. W., Schneider, N., Simon, R., Stutzki, J., Wolfire, M., and Tielens, A. G. G. M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We explore the potential of the Gaussian Mixture Model (GMM), an unsupervised machine learning method, to identify coherent physical structures in the ISM. The implementation we present can be used on any kind of spatially and spectrally resolved data set. We provide a step-by-step guide to use these models on different sources and data sets. Following the guide, we run the models on NGC 1977, RCW 120 and RCW 49 using the [CII] 158 $\mu$m mapping observations from the SOFIA telescope. We find that the models identified 6, 4 and 5 velocity coherent physical structures in NGC 1977, RCW 120 and RCW 49, respectively, which are validated by analysing the observed spectra towards these structures and by comparison to earlier findings. In this work we demonstrate that GMM is a powerful tool that can better automate the process of spatial and spectral analysis to interpret mapping observations., Comment: 19 pages, 14 figures
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- 2023
4. Vitrovariation et régénération par embryogenèse somatique à partir d'embryons mûrs de blé tendre (Triticum aestivum L. var. 'Nesma' 149) : effet du borate de sodium, de la fragmentation et du scutellum
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Karim, R., Chlyah, H., Douira, A., and Hsaine, M.
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Triticum aestivum ,somatic embryos ,in vitro regeneration ,somatic embryogenesis ,somaclonal variation ,borates ,Biotechnology ,TP248.13-248.65 ,Environmental sciences ,GE1-350 - Abstract
Vitrovariation and regeneration by somatic embryogenesis from mature embryos of common wheat (Triticum aestivum L. Var. 'Nesma' 149): effect of the borate of sodium, the fragmentation and the scutellum. The combined effects of the scutellum, the fragmentation and sodium borate, on the embryogenic capacity of ripe zygotic embryos of common wheat (Triticum aestivum L. var. 'Nesma' 149) were studied. The morphological characters and yield of the regenerated plants differ from control plants and indicate somaclonales variations. The mediums containing borax (0.75 g.l-1) and comprising explants resulting from the longitudinal fragmentation of the zygotic embryos with scutellum, initiated high percentages of embryogenic callus and of regeneration over one long period of culture, with large size somatic embryos as well as a weak somaclonale variation and one very low necrosis of callus. Whereas the mediums containing less or no borax and explants resulting from transversely cut zygotic embryos and without scutellum show opposite results.
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- 2011
5. Characteristics and 6-Month Outcomes in Patients with Rheumatoid Arthritis Initiating Infliximab Biosimilar IFX-dyyb in a Real-World Setting
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Joshua F. Baker, Catherine Bakewell, Ara Dikranian, Gordon Lam, Jacqueline O’Brien, Page C. Moore, Miao Yu, Peter Hur, and Karim R. Masri
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Biologic ,Biosimilar ,CorEvitas Registry ,IFX-dyyb ,DMARD ,Effectiveness ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Introduction Real-world studies describing biosimilar initiation or switching in patients with rheumatoid arthritis (RA) are limited. The aim of this study was to assess treatment patterns and effectiveness of real-world patients with RA initiating infliximab biosimilar IFX-dyyb (CT-P13; Inflectra®) in the USA. Methods This observational study evaluated patients with RA from the CorEvitas RA Registry who initiated IFX-dyyb and had Clinical Disease Activity Index (CDAI) recorded at baseline and 6 months. The primary outcome was reaching low disease activity (LDA; CDAI ≤ 10) at 6 months in patients with moderate or high disease activity (CDAI > 10) at baseline. Secondary outcomes were change at 6 months in CDAI and certain patient-reported outcomes (PROs). Patient data were stratified by prior treatment: biologic/targeted synthetic disease-modifying antirheumatic drug (tsDMARD)-naïve, reference infliximab (IFX-REF) or IFX biosimilar, or a non-IFX biologic or tsDMARD. Results Of 318 patients initiating IFX-dyyb, 176 had baseline and 6-month CDAI scores; 73 (41%) switched from IFX, 61 (35%) switched from another non-IFX/biologic/tsDMARD, 32 (18%) were naïve to biologics/tsDMARDs, and 10 (6%) switched from an IFX biosimilar. Among patients with moderate or high disease activity at baseline, 32.9% (95% CI 22.9, 42.9) achieved LDA at 6 months. Mean 6-month change from baseline in CDAI was − 1.8 (95% CI − 3.3, − 0.3) overall; − 4.7 (− 7.6, − 1.7) in patients who switched from a non-IFX biologic/tsDMARD, − 4.1 (− 7.8, − 0.3) in biologic/tsDMARD-naïve patients, and 1.1 (− 0.4, 2.6) in patients who switched from IFX-REF/IFX biosimilar. Other clinical outcomes/PROs improved at 6 months. Of the IFX-dyyb initiators, 68% remained on IFX-dyyb at 6 months. Conclusion In this real-world population of patients with RA initiating IFX-dyyb, the majority switched from IFX-REF or a non-IFX biologic/tsDMARD. CDAI remained stable in patients switching from IFX-REF/IFX biosimilar and improved in patients switching from a non-IFX biologic/tsDMARD and in biologic/tsDMARD-naïve patients.
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- 2024
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6. SOFIA FEEDBACK survey: PDR diagnostics of stellar feedback in different regions of RCW 49
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Tiwari, M., Wolfire, M., Pound, M. W., Tarantino, E., Karim, R., Bonne, L., Buchbender, C., Güsten, R., Guevara, C., Kabanovic, S., Kavak, Ü., Mertens, M., Schneider, N., Simon, R., Stutzki, J., and Tielens, A. G. G. M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We quantified the effects of stellar feedback in RCW 49 by determining the physical conditions in different regions using the [CII] 158 $\mu$m and [OI] 63 $\mu$m observations from SOFIA, the $^{12}$CO (3-2) observations from APEX and the H$_2$ line observations from Spitzer telescopes. Large maps of RCW 49 were observed with the SOFIA and APEX telescopes, while the Spitzer observations were only available towards three small areas. From our qualitative analysis, we found that the H$_2$ 0-0 S(2) emission line probes denser gas compared to the H$_2$ 0-0 S(1) line. In four regions ("northern cloud", "pillar", "ridge", and "shell"), we compared our observations with the updated PDR Toolbox models and derived the integrated far-ultraviolet flux between 6-13.6 eV ($G_{\rm 0}$), H nucleus density ($n$), temperatures and pressures. We found the ridge to have the highest $G_{\rm 0}$ (2.4 $\times$ 10$^3$ Habing units), while the northern cloud has the lowest $G_{\rm 0}$ (5 $\times$ 10$^2$ Habing units). This is a direct consequence of the location of these regions with respect to the Wd2 cluster. The ridge also has a high density (6.4 $\times$ 10$^3$ cm$^{-3}$), which is consistent with its ongoing star formation. Among the Spitzer positions, we found the one closest to the Wd2 cluster to be the densest, suggesting an early phase of star formation. Furthermore, the Spitzer position that overlaps with the shell was found to have the highest $G_{\rm 0}$ and we expect this to be a result of its proximity to an O9V star., Comment: 18 pages, 12 figures
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- 2022
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7. The SOFIA FEEDBACK Legacy Survey: Dynamics and mass ejection in the bipolar HII region RCW 36
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Bonne, L., Schneider, N., García, P., Bij, A., Broos, P., Fissel, L., Guesten, R., Jackson, J., Simon, R., Townsley, L., Zavagno, A., Aladro, R., Buchbender, C., Guevara, C., Higgins, R., Jacob, A. M., Kabanovic, S., Karim, R., Soam, A., Stutzki, J., Tiwari, M., Wyrowski, F., and Tielens, A. G. G. M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present [CII] 158 $\mu$m and [OI] 63 $\mu$m observations of the bipolar HII region RCW 36 in the Vela C molecular cloud, obtained within the SOFIA legacy project FEEDBACK, which is complemented with APEX $^{12/13}$CO(3-2) and Chandra X-ray (0.5-7 keV) data. This shows that the molecular ring, forming the waist of the bipolar nebula, expands with a velocity of 1 - 1.9 km s$^{-1}$. We also observe an increased linewidth in the ring indicating that turbulence is driven by energy injection from the stellar feedback. The bipolar cavity hosts blue-shifted expanding [CII] shells at 5.2$\pm$0.5$\pm$0.5 km s$^{-1}$ (statistical and systematic uncertainty) which indicates that expansion out of the dense gas happens non-uniformly and that the observed bipolar phase might be relatively short ($\sim$0.2 Myr). The X-ray observations show diffuse emission that traces a hot plasma, created by stellar winds, in and around RCW 36. At least 50 \% of the stellar wind energy is missing in RCW 36. This is likely due to leakage which is clearing even larger cavities around the bipolar RCW 36 region. Lastly, the cavities host high-velocity wings in [CII] which indicates relatively high mass ejection rates ($\sim$5$\times$10$^{-4}$ M$_{\odot}$ yr$^{-1}$). This could be driven by stellar winds and/or radiation pressure, but remains difficult to constrain. This local mass ejection, which can remove all mass within 1 pc of RCW 36 in 1-2 Myr, and the large-scale clearing of ambient gas in the Vela C cloud indicates that stellar feedback plays a significant role in suppressing the star formation efficiency (SFE)., Comment: 38 pages, 27 figures, 8 tables, accepted in ApJ
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- 2022
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8. Strong Ill-Posedness in $L^\infty$ for the Riesz Transform Problem
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Elgindi, Tarek M. and Khalil, Karim R. Shikh
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Mathematics - Analysis of PDEs - Abstract
We prove strong ill-posedness in $L^{\infty}$ for linear perturbations of the 2d Euler equations of the form: \[\partial_t \omega + u\cdot\nabla\omega = R(\omega),\] where $R$ is any non-trivial second order Riesz transform. Namely, we prove that there exist smooth solutions that are initially small in $L^{\infty}$ but become arbitrarily large in short time. Previous works in this direction relied on the strong ill-posedness of the linear problem, viewing the transport term perturbatively, which only led to mild growth. In this work we derive a nonlinear model taking all of the leading order effects into account to determine the precise pointwise growth of solutions for short time. Interestingly, the Euler transport term does counteract the linear growth so that the full nonlinear equation grows an order of magnitude less than the linear one. In particular, the (sharp) growth rate we establish is consistent with the global regularity of smooth solutions., Comment: 24 pages
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- 2022
9. Filamentary structures of ionized gas in Cygnus X
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Emig, K. L., White, G. J., Salas, P., Karim, R. L., van Weeren, R. J., Teuben, P. J., Zavagno, A., Chiu, P., Haverkorn, M., Oonk, J. B. R., Orrú, E., Polderman, I. M., Reich, W., Röttgering, H. J. A., and Tielens, A. G. G. M.
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Astrophysics - Astrophysics of Galaxies - Abstract
Ionized gas probes the influence of massive stars on their environment. The Cygnus X region (d~1.5 kpc) is one of the most massive star forming complexes in our Galaxy, in which the Cyg OB2 association (age of 3-5 Myr and stellar mass $2 \times 10^{4}$ M$_{\odot}$) has a dominant influence. We observe the Cygnus X region at 148 MHz using the Low Frequency Array (LOFAR) and take into account short-spacing information during image deconvolution. Together with data from the Canadian Galactic Plane Survey, we investigate the morphology, distribution, and physical conditions of low-density ionized gas in a $4^{\circ} \times 4^{\circ}$ (100 pc $\times$ 100 pc) region at a resolution of 2' (0.9 pc). The Galactic radio emission in the region analyzed is almost entirely thermal (free-free) at 148 MHz, with emission measures of $10^3 < EM~{\rm[pc~cm^{-6}]} < 10^6$. As filamentary structure is a prominent feature of the emission, we use DisPerSE and FilChap to identify filamentary ridges and characterize their radial ($EM$) profiles. The distribution of radial profiles has a characteristic width of 4.3 pc and a power-law distribution ($\beta = -1.8 \pm 0.1$) in peak $EM$ down to our completeness limit of 4200 pc cm$^{-6}$. The electron densities of the filamentary structure range from $10 < n_e~{\rm[cm^{-3}]} < 400$ with a median value of 35 cm$^{-3}$, remarkably similar to [N II] surveys of ionized gas. Cyg OB2 may ionize at most two-thirds of the total ionized gas and the ionized gas in filaments. More than half of the filamentary structures are likely photoevaporating surfaces flowing into a surrounding diffuse (~5 cm$^{-3}$) medium. However, this is likely not the case for all ionized gas ridges. A characteristic width in the distribution of ionized gas points to the stellar winds of Cyg OB2 creating a fraction of the ionized filaments through swept-up ionized gas or dissipated turbulence., Comment: 19 pages, 14 figures, 1 table; accepted for publication in A&A
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- 2022
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10. Time Dependency, Data Flow, and Competitive Advantage
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Valavi, Ehsan, Hestness, Joel, Iansiti, Marco, Ardalani, Newsha, Zhu, Feng, and Lakhani, Karim R.
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Computer Science - Machine Learning ,Computer Science - Computation and Language ,Economics - General Economics - Abstract
Data is fundamental to machine learning-based products and services and is considered strategic due to its externalities for businesses, governments, non-profits, and more generally for society. It is renowned that the value of organizations (businesses, government agencies and programs, and even industries) scales with the volume of available data. What is often less appreciated is that the data value in making useful organizational predictions will range widely and is prominently a function of data characteristics and underlying algorithms. In this research, our goal is to study how the value of data changes over time and how this change varies across contexts and business areas (e.g. next word prediction in the context of history, sports, politics). We focus on data from Reddit.com and compare the value's time-dependency across various Reddit topics (Subreddits). We make this comparison by measuring the rate at which user-generated text data loses its relevance to the algorithmic prediction of conversations. We show that different subreddits have different rates of relevance decline over time. Relating the text topics to various business areas of interest, we argue that competing in a business area in which data value decays rapidly alters strategies to acquire competitive advantage. When data value decays rapidly, access to a continuous flow of data will be more valuable than access to a fixed stock of data. In this kind of setting, improving user engagement and increasing user-base help creating and maintaining a competitive advantage., Comment: 24 Pages
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- 2022
11. Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial
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Salluzzi, Marina, Blenkin, Nicole, Dueck, Ashley, Doram, Craig, Zhang, Qiao, Kenney, Carol, Ryckborst, Karla, Bohn, Shelly, Collier, Quentin, Taylor, Frances, Lethebe, B. Cord, Jambula, Anitha, Sage, Kayla, Toussaint, Lana, Save, Supryia, Lee, Jaclyn, Laham, N, Sultan, A.A., Deepak, A., Sitaram, A., Demchuk, Andrew M., Lockey, A., Micielli, A., Wadhwa, A., Arabambi, B., Graham, B., Bogiatzi, Chrysi, Doshi, Darshan, Chakraborty, D., Kim, Diana, Vasquez, D, Singh, D, Tse, Dominic, Harrison, E., Smith, E.E., Teleg, E., Klourfeld, E., Klein, G., Sebastian, I.A., Evans, J, Hegedus, J, Kromm, J, Lin, K, Ignacio, K, Ghavami, Kimia, Ismail, M., Moores, M., Panzini, M.A., Boyko, M., Almekhlafi, M.A., Newcommon, Nancy, Maraj, N., Imoukhuede, O., Volny, O., Stys, Peter, Couillard, Phillipe, Ojha, P., Eswaradass, P., Joundi, Raed, Singh, R., Asuncion, R.M., Muir, R.T., Dey, S., Mansoor, S., Wasyliw, S., Nagendra, S., Hu, Sherry, Althubait, S., Chen, S., Bal, S., Van Gaal, Stephen, Peters, Steven, Ray, Sucharita, Chaturvedi, S., Subramaniam, Suresh, Fu, Vivian, Villaluna, K., Maclean, G., King-Azote, P., Ma, C., Plecash, A., Murphy, C., Gorman, J., Wilson, L., Zhou, L., Benevente, O., Teal, P., Yip, S., Mann, S., Dewar, B., Demetroff, M., Shamloul, R., Beardshaw, R., Roberts, S., Blaquiere, D., Stotts, G., Shamy, M., Bereznyakova, O., Fahed, R., Alesefir, W., Lavoie, Suzy, Hache, A., Collard, K, Mackey, A., Gosselin-Lefebvre, S., Verreault, S., Beauchamp, B., Lambourn, L., Khaw, A., Mai, L., Sposato, L., Bres Bullrich, M., Azarpazhooh, R., Fridman, S., Kapoor, A., Southwell, A., Bardi, E., Fatakdawala, I., Kamra, M, Lopes, K., Popel, N., Norouzi, V., Liu, A., Liddy, A.M., Ghoari, B., Hawkes, C., Enriquez, C.A., Gladstone, D.J., Manosalva Alzate, H.A., Khosravani, H., Hopyan, J.J., Sivakumar, K., Son, M., Boulos, M.I., Hamind, M.A., Swartz, R.H., Murphy, R., Reiter, S., Fitzpatrick, T., Bhandari, V., Good, J., Penn, M., Naylor, M., Frost, S., Cayley, A., Akthar, F., Williams, J., Kalman, L., Crellin, L., Wiegner, R., Singh, R.S., Stewart, T., To, W., Singh, S., Pikula, A., Jaigobin, C., Carpani, F., Silver, F., Janssen, H., Schaafsma, J., del Campo, M., Alskaini, M., Rajendram, P., Fairall, P., Granfield, B., Crawford, D., Jabs, J., White, L., Sivakumar, L., Piquette, L., Nguyen, T., Nomani, A., Wagner, A., Alrohimi, A., Butt, A., D'Souza, A., Gajurel, B., Vekhande, C., Kamble, H., Kalashyan, H., Lloret, M., Benguzzi, M., Arsalan, N., Ishaque, N., Ashayeriahmadabad, R., Samiento, R., Hosseini, S., Kazi, S., Das, S., Sugumar, T., Selchen, D., Kostyrko, P., Muccilli, A., Saposnik, A.G., Vandervelde, C., Ratnayake, K., McMillan, S., Katsanos, A., Shoamanesh, A., Sahlas, D.J., Naidoo, V., Todorov, V., Toma, H., Brar, J., Lee, J., Horton, M., Shand, E., Weatherby, S., Jin, A., Durafourt, B., Jalini, S., Gardner, A., Tyson, C., Junk, E., Foster, K., Bolt, K., Sylvain, N., Maley, S., Urroz, L., Peeling, L., Kelly, M., Whelan, R., Cooley, R., Teitelbaum, J., Boutayeb, A., Moore, A., Cole, E., Waxman, L., Ben-Amor, N., Sanchez, R., Khalil, S., Nehme, A., Legault, C., Tampieri, D., Ehrensperger, E., Vieira, L., Cortes, M., Angle, M., Hannouche, M., Badawy, M., Werner, K., Wieszmuellner, S., Langer, A., Gisold, A., Zach, H., Rommer, P., Macher, S., Blechinger, S., Marik, W., Series, W., Baumgartinger, M., Krebs, S., Koski, J., Eirola, S., Ivanoff, T., Erakanto, A., Kupari, L., Sibolt, G., Panula, J., Tomppo, L., Tiainen, M., Ahlstrom, M., Martinez Majander, N., Suomalainen, O., Raty, S., Levi, C., Kerr, E., Allen, J., Kaauwai, L.P., Belevski, L., Russell, M., Ormond, S., Chew, A., Loiselle, A., Royan, A., Hughes, B., Garcia Esperon, C., Pepper, E., Miteff, F., He, J., Lycett, M., Min, M., Murray, N., Pavey, N., Starling de Barros, R., Gangadharan, S., Dunkerton, S., Waller, S., Canento Sanchez, T., Wellings, T., Edmonds, G., Whittaker, K.A., Ewing, M., Lee, P., Singkang, R., McDonald, A., Dos Santos, A., Shin, C., Jackson, D., Tsoleridis, J., Fisicchia, L., Parsons, N., Shenoy, N., Smith, S., Sharobeam, A., Balabanski, A., Park, A., Williams, C., Pavlin-Premri, D., Rodrigues, E., Alemseged, F., Ng, F., Zhao, H., Beharry, J., Ng, J.L., Williamson, J., Wong, J.Z.W., Li, K., Kwan, M.K., Valente, M., Yassi, N., Yogendrakumar, V., McNamara, B., Buchanan, C., McCarthy, C., Thomas, G., Stephens, K., Chung, M., Chung, M.F., Tang, M., Busch, T., Frost, T., Lee, R., Stuart, N., Pachani, N., Menon, A., Borojevic, B., Linton, C.M., Garcia, G., Callaly, E.P., Dewey, H., Liu, J., Chen, J., Wong, J., Nowak, K., To, K., Lizak, N.S., Bhalala, O., Park, P., Tan, P., Martins, R., Cody, R., Forbes, R., Chen, S.K., Ooi, S., Tu, S., Dang, Y.L., Ling, Z., Cranefield, J., Drew, R., Tan, A., Kurunawai, C., Harvey, J., Mahadevan, J.J., Cagi, L., Palanikumar, L., Chia, L.N., Goh, R., El-Masri, S., Urbi, B., Rapier, C., Berrill, H., McEvoy, H., Dunning, R., Kuriakose, S., Chad, T., Sapaen, V., Sabet, A., Shah, D., Yeow, D., Lilley, K., Ward, K., Mozhy Mahizhnan, M., Tan, M., Lynch, C., Coveney, S., Tobin, K., McCabe, J., Marnane, M., Murphy, S., Large, M., Moynihan, B., Boyle, K., Sanjuan, E., Sanchis, M., Boned, S., Pancorbo, O., Sala, V., Garcia, L., Garcia-Tornel, A., Juega, J., Pagola, J., Santana, K., Requena, M., Muchada, M., Olive, M., Lozano, P.J., Rubiera, M., Deck, M., Rodriguez, N., Gomez, B., Reyes Munoz, F.J., Gomez, A.S., Sanz, A.C., Garcia, E.C., Penacoba, G., Ramos, M.E., de Lera Alfonso, M., Feliu, A, Pardo, L., Ramirez, P., Murillo, A., Lopez Dominguez, D., Rodriguez, J., Terceno Izaga, M., Reina, M., Viturro, S.B., Bojaryn, U., Vera Monge, V.A., Silva Blas, Y., R Siew, R., Agustin, S J, Seet, C., Tianming, T., d'Emden, A., Murray, A., Welch, A., Hatherley, K., Day, N., Smith, W., MacRae, E., Mitchell, E.S., Mahmood, A., Elliot, J., Neilson, S., Biswas, V., Brown, C., Lewis, A., Ashton, A., Werring, D., Perry, R., Muhammad, R., Lee, Y.C., Black, A., Robinson, A., Williams, A., Banaras, A., Cahoy, C., Raingold, G., Marinescu, M., Atang, N., Bason, N., Francia, N., Obarey, S., Feerick, S., Joseph, J., Schulz, U., Irons, R., Benjamin, J., Quinn, L., Jhoots, M., Teal, R., Ford, G., Harston, G., Bains, H., Gbinigie, I., Mathieson, P., Sim, C.H., Hayter, E., Kennedy, K., Binnie, L., Priestley, N., Williams, R., Ghatala, R., Stratton, S., Blight, A., Zhang, L., Davies, A., Duffy, H., Roberts, J., Homer, J., Roberts, K., Dodd, K., Cawley, K., Martin, M., Leason, S., Cotgreave, S., Taylor, T., Nallasivan, A., Haider, S., Chakraborty, T., Webster, T., Gil, A., Martin, B., Joseph, B., Cabrera, C., Jose, D., Man, J., Aquino, J., Sebastian, S., Osterdahl, M., Kwan, M., Matthew, M., Ike, N., Bello, P., Wilding, P., Fuentes, R., Shah, R., Mashate, S., Patel, T., Nwanguma, U., Dave, V., Haber, A., Lee, A., O'Sullivan, A., Drumm, B., Dawson, A.C., Matar, T., Roberts, D., Taylor, E., Rounis, E., El-Masry, A., O'Hare, C., Kalladka, D., Jamil, S., Auger, S., Raha, O., Evans, M., Vonberg, F., Kalam, S., Ali Sheikh, A., Jenkins, I.H., George, J., Kwan, J., Blagojevic, J., Saeed, M., Haji-Coll, M., Tsuda, M., Sayed, M., Winterkron, N., Thanbirajah, N., Vittay, O., Karim, R., Smail, R.C., Gauhar, S., Elmamoun, S., Malani, S., Pralhad Kelavkar, S., Hiden, J., Ferdinand, P., Sanyal, R., Varquez, R., Smith, B., Okechukwu, C., Fox, E., Collins, E., Courtney, K., Tauro, S., Patterson, C., McShane, D., Roberts, G., McIImoyle, J., McGuire, K., Fearon, P., Gordon, P., Isaacs, K., Lucas, K., Smith, L., Dews, L., Bates, M., Lawrence, S., Heeley, S., Patel, V., Chin, Y.M., Sims, D., Littleton, E., Khaira, J., Nadar, K., Kieliszkowska, A., Sari, B., Domingos Belo, C., Smith, E., Manolo, E.Y., Aeron-Thomas, J., Doheny, M., Garcia Pardo, M., Recaman, M., Tibajia, M.C., Aissa, M., Mah, Y., Yu, T., Meenakshisundaram, S., Heller, S., Alsukhni, R., Williams, O., Farag, M., Benger, M., Engineer, A., Bayhonan, S., Conway, S., Bhalla, A., Nouvakis, D., Theochari, E., Boyle, F., Teo, J., King-Robson, J., Law, K.Y., Sztriha, L., McGovern, A., Day, D., Mitchell-Douglas, J., Francis, J., Iqbal, A., Punjabivaryani, P., Anonuevo Reyes, J., Anonuevo Reyes, M., Pauls, M., Buch, A., Hedstrom, A., Hutchinson, C., Kirkland, C., Newham, J., Wilkes, G., Fleming, L., Fleck, N., Franca, A., Chwal, B., Oldoni, C., Mantovani, G., Noll, G., Zanella, L., Soma, M., Secchi, T., Borelli, W., Rimoli, B.P., da Cunha Silva, G.H., Machado Galvao Mondin, L.A., Barbosa Cerantola, R., Imthon, A.K., Esaki, A.S., Camilo, M., Vincenzi, O.C., ds Cruz, R.R., Morillos, M.B., Riccioppa Rodrigues, G.G., Santos Ferreira, K., Pazini, A.M., Pena Pereira, M.A., de Albuquerque, A.L.A., Massote Fontanini, C.E., Matinez Rubio, C.F., dos Santos, D.T., Dias, F.A., Alves, F.F.A., Milani, C., Pegorer Santos, B., Winckler, F., De Souza, J.T., Bonome, L.A.M., Cury Silva, V.A., Teodoro, R.S., Modolo, G.P., Ferreira, N.C., Barbosa dos Santos, D.F., dos Santos Moreira, J.C., Cruz Guedes de Morais, A.B., Vieira, J., Mendes, G., de Queiroz, J.P., Coutts, Shelagh B, Ankolekar, Sandeep, Appireddy, Ramana, Arenillas, Juan F, Assis, Zarina, Bailey, Peter, Barber, Philip A, Bazan, Rodrigo, Buck, Brian H, Butcher, Ken S, Camden, Marie-Christine, Campbell, Bruce C V, Casaubon, Leanne K, Catanese, Luciana, Chatterjee, Kausik, Choi, Philip M C, Clarke, Brian, Dowlatshahi, Dar, Ferrari, Julia, Field, Thalia S, Ganesh, Aravind, Ghia, Darshan, Goyal, Mayank, Greisenegger, Stefan, Halse, Omid, Horn, Mackenzie, Hunter, Gary, Imoukhuede, Oje, Kelly, Peter J, Kennedy, James, Kleinig, Timothy J, Krishnan, Kailash, Lima, Fabricio, Mandzia, Jennifer L, Marko, Martha, Martins, Sheila O, Medvedev, George, Menon, Bijoy K, Mishra, Sachin M, Molina, Carlos, Moussaddy, Aimen, Muir, Keith W, Parsons, Mark W, Penn, Andrew M W, Pille, Arthur, Pontes-Neto, Octávio M, Roffe, Christine, Serena, Joaquin, Simister, Robert, Singh, Nishita, Spratt, Neil, Strbian, Daniel, Tham, Carol H, Wiggam, M Ivan, Williams, David J, Willmot, Mark R, Wu, Teddy, Yu, Amy Y X, Zachariah, George, Zafar, Atif, Zerna, Charlotte, and Hill, Michael D
- Published
- 2024
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12. Loss of New Ideas: Potentially Long-lasting Effects of the Pandemic on Scientists
- Author
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Gao, Jian, Yin, Yian, Myers, Kyle R., Lakhani, Karim R., and Wang, Dashun
- Subjects
Computer Science - Digital Libraries ,Physics - Physics and Society - Abstract
Extensive research has documented the immediate impacts of the COVID-19 pandemic on scientists, yet it remains unclear if and how such impacts have shifted over time. Here we compare results from two surveys of principal investigators, conducted between April 2020 and January 2021, along with analyses of large-scale publication data. We find that there has been a clear sign of recovery in some regards, as scientists' time spent on their work has almost returned to pre-pandemic levels. However, the latest data also reveals a new dimension in which the pandemic is affecting the scientific workforce: the rate of initiating new research projects. Except for the small fraction of scientists who directly engaged in COVID-related research, most scientists started significantly fewer new research projects in 2020. This decline is most pronounced amongst the same demographic groups of scientists who reported the largest initial disruptions: female scientists and those with young children. Yet in sharp contrast to the earlier phase of the pandemic, when there were large disparities across scientific fields, this loss of new projects appears remarkably homogeneous across fields. Analyses of large-scale publication data reveal a global decline in the rate of new collaborations, especially in non-COVID-related preprints, which is consistent with the reported decline in new projects. Overall, these findings highlight that, while the end of the pandemic may appear in sight in some countries, its large and unequal impact on the scientific workforce may be enduring, which may have broad implications for inequality and the long-term vitality of science., Comment: 14 pages, 2 figures, with supplementary information
- Published
- 2021
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13. Protective Effect of Fenugreek Supplementation against Mercury Toxicity on Sperm Parameters, Serum Testosterone and Testicular Tissue in the Rat
- Author
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Jalal A. Karim and Karim R. Hamad
- Subjects
fenugreek ,mercury ,sperm ,testis ,mda ,testosterone ,Science - Abstract
Background and objectives:The purpose of the current study was to investigate the effects of fenugreek supplementation against toxic effect of mercuric chloride (HgCl2)on Body weight (B.W), testis and epididymis weight, some sperm parameters, serum testosterone, serum MDA, and testis histology in the rat.Methods: Twenty eight male albino rats weights ranging from 254 to 302 gm and were divided randomly and equally into 4 groups. Group I: control, Group II: Rats received drinking water contained HgCl2 100 mg/L ad libitum, Group III: Rats received drinking water contained HgCl2 100 mg/L ad libitum, and fenugreek (F1) 0.75 mg/kg/day orally by gavage, Group IV: Rats received drinking water contained HgCl2 100 mg/L ad libitumand fenugreek (F2) 1.5 mg/kg/day orally by gavage. The treatments were given for six weeks.Results: Treatment with F1 caused no substantial changes in body weight, absolute weight, andrelative weight of testis and epididymis, sperm count and testosterone. Whereas sperm motility, and normal sperm were increased significantly, and serum MDA was decreased significantly from HgCl2 group. Improvement was observed partially in testis histology. Meanwhile, the protective effect in F2 generally was more than in F1.Conclusions: the present study revealed that the antioxidant activity of fenugreek supplementreduced toxic effect of mercury. In addition, steroids and/or phytoestrogens in fenugreek possibly compensated the reduced testosterone which resulted at least in part in improvement of sperm parameters and testis histology
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- 2023
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14. Electrodeposition of nickel selenides thin films for high-performance hybrid supercapacitor
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Bekhit, Samah M., Metwally, W., Mohamed, Saad G., Abdel-Karim, R., El-Raghy, S.M., and Ghayad, Ibrahim M.
- Published
- 2024
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15. SOFIA FEEDBACK survey: exploring the dynamics of the stellar wind driven shell of RCW 49
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Tiwari, M., Karim, R., Pound, M. W., Wolfire, M., Jacob, A., Buchbender, C., Güsten, R., Guevara, C., Higgins, R. D., Kabanovic, S., Pabst, C., Ricken, O., Schneider, N., Simon, R., Stutzki, J., and Tielens, A. G. G. M.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We unveil the stellar wind driven shell of the luminous massive star-forming region of RCW 49 using SOFIA FEEDBACK observations of the [CII] 158 $\mu$m line. The complementary dataset of the $^{12}$CO and $^{13}$CO J = 3 - 2 transitions is observed by the APEX telescope and probes the dense gas toward RCW 49. Using the spatial and spectral resolution provided by the SOFIA and APEX telescopes, we disentangle the shell from a complex set of individual components of gas centered around RCW 49. We find that the shell of radius ~ 6 pc is expanding at a velocity of 13 km s$^{-1}$ toward the observer. Comparing our observed data with the ancillary data at X-Ray, infrared, sub-millimeter and radio wavelengths, we investigate the morphology of the region. The shell has a well defined eastern arc, while the western side is blown open and is venting plasma further into the west. Though the stellar cluster, which is ~ 2 Myr old gave rise to the shell, it only gained momentum relatively recently as we calculate the shell's expansion lifetime ~ 0.27 Myr, making the Wolf-Rayet star WR20a a likely candidate responsible for the shell's re-acceleration., Comment: 31 pages, 17 figures
- Published
- 2021
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16. Nanoporous Materials as Versatile Nanoplatforms for Drug Delivery Applications: Properties, Recent Progress, and Challenges
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Abdel-Karim, R., Malviya, Rishabha, editor, and Sundram, Sonali, editor
- Published
- 2023
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17. FEEDBACK: a SOFIA Legacy Program to Study Stellar Feedback in Regions of Massive Star Formation
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Schneider, N., Simon, R., Guevara, C., Buchbender, C., Higgins, R. D., Okada, Y., Stutzki, J., Guesten, R., Anderson, L. D., Bally, J., Beuther, H., Bonne, L., Bontemps, S., Chambers, E., Csengeri, T., Graf, U. U., Gusdorf, A., Jacobs, K., Kabanovic, S., Karim, R., Luisi, M., Menten, K., Mertens, M., Mookerjea, B., Ossenkopf-Okada, V., Pabst, C., Pound, M. W., Richter, H., Reyes, N., Ricken, O., Roellig, M., Russeil, D., Sanchez-Monge, A., Sandell, G., Tiwari, M., Wiesemeyer, H., Wolfire, M., Wyrowski, F., Zavagno, A., and Tielens, A. G. G. M.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
FEEDBACK is a SOFIA legacy program dedicated to study the interaction of massive stars with their environment. It performs a survey of 11 galactic high mass star forming regions in the 158 $\mu$m (1.9 THz) line of CII and the 63 $\mu$m (4.7 THz) line of OI. We employ the 14 pixel LFA and 7 pixel HFA upGREAT instrument to spectrally resolve (0.24 MHz) these FIR structure lines. With an observing time of 96h, we will cover $\sim$6700 arcmin$^2$ at 14.1$''$ angular resolution for the CII line and 6.3$''$ for the OI line. The observations started in spring 2019 (Cycle 7). Our aim is to understand the dynamics in regions dominated by different feedback processes from massive stars such as stellar winds, thermal expansion, and radiation pressure, and to quantify the mechanical energy injection and radiative heating efficiency. The CII line provides the kinematics of the gas and is one of the dominant cooling lines of gas for low to moderate densities and UV fields. The OI line traces warm and high-density gas, excited in photodissociations regions with a strong UV field or by shocks. The source sample spans a broad range in stellar characteristics from single OB stars, to small groups of O stars, to rich young stellar clusters, to ministarburst complexes. It contains well-known targets such as Aquila, the Cygnus X region, M16, M17, NGC7538, NGC6334, Vela, and W43 as well as a selection of HII region bubbles, namely RCW49, RCW79, and RCW120. These CII maps, together with the less explored OI 63 $\mu$m line, provide an outstanding database for the community. They will be made publically available and will trigger further studies and follow-up observations.
- Published
- 2020
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18. Quantifying the Immediate Effects of the COVID-19 Pandemic on Scientists
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Myers, Kyle R., Tham, Wei Yang, Yin, Yian, Cohodes, Nina, Thursby, Jerry G., Thursby, Marie C., Schiffer, Peter E., Walsh, Joseph T., Lakhani, Karim R., and Wang, Dashun
- Subjects
Physics - Physics and Society - Abstract
The COVID-19 pandemic has undoubtedly disrupted the scientific enterprise, but we lack empirical evidence on the nature and magnitude of these disruptions. Here we report the results of a survey of approximately 4,500 Principal Investigators (PIs) at U.S.- and Europe-based research institutions. Distributed in mid-April 2020, the survey solicited information about how scientists' work changed from the onset of the pandemic, how their research output might be affected in the near future, and a wide range of individuals' characteristics. Scientists report a sharp decline in time spent on research on average, but there is substantial heterogeneity with a significant share reporting no change or even increases. Some of this heterogeneity is due to field-specific differences, with laboratory-based fields being the most negatively affected, and some is due to gender, with female scientists reporting larger declines. However, among the individuals' characteristics examined, the largest disruptions are connected to a usually unobserved dimension: childcare. Reporting a young dependent is associated with declines similar in magnitude to those reported by the laboratory-based fields and can account for a significant fraction of gender differences. Amidst scarce evidence about the role of parenting in scientists' work, these results highlight the fundamental and heterogeneous ways this pandemic is affecting the scientific workforce, and may have broad relevance for shaping responses to the pandemic's effect on science and beyond.
- Published
- 2020
19. Status drives how we cite: Evidence from thousands of authors
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Teplitskiy, Misha, Duede, Eamon, Menietti, Michael, and Lakhani, Karim R.
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Computer Science - Social and Information Networks - Abstract
Researchers cite works for a variety of reasons, including some having nothing to do with acknowledging influence. The distribution of different citation types in the literature, and which papers attract which types, is poorly understood. We investigate high-influence and low-influence citations and the mechanisms producing them using 17,154 ground-truth citation types provided via survey by 9,380 authors systematically sampled across academic fields. Overall, 54% of citations denote little-to-no influence and these citations are concentrated among low status (lightly cited) papers. In contrast, high-influence citations are concentrated among high status (highly cited) papers through a number of steps that resemble a pipeline. Authors discover highly cited papers earlier in their projects, more often through social contacts, and read them more closely. Papers' status, above and beyond any quality differences, directly helps determine their pipeline: experimentally revealing or hiding citation counts during the survey shows that low counts cause lowered perceptions of quality. Accounting for citation types thus reveals a "double status effect": in addition to affecting how often a work is cited, status affects how meaningfully it is cited. Consequently, highly cited papers are even more influential than their raw citation counts suggest., Comment: Heavily revised narrative in this version including new title, figures, abstract, and narrative structure. Central empirical findings unchanged
- Published
- 2020
20. Genetic variations among the isolates of Bipolaris Maydis based on phenotypic and molecular markers/Variacoes geneticas entre os isolados de Bipolaris Maydis podem ser baseadas em marcadores fenotipicos e moleculares
- Author
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Nadeem, A., Hussain, S., Fareed, A., Fahim, M., Iqbal, T., Ahmad, Z., Saeedullah, Karim, R., and Akbar, A.
- Published
- 2024
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21. Nanoporous Materials as Versatile Nanoplatforms for Drug Delivery Applications: Properties, Recent Progress, and Challenges
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Abdel-Karim, R., primary
- Published
- 2023
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22. Sensing Materials: Nanostructured Biomaterials
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Abdel-Karim, R., primary
- Published
- 2023
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23. Erosion–Corrosion Behaviour of ASTM A106 GR.B Carbon Steel Pipelines
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Reda, Y., Gamal, A., Abdel-Karim, R., and El-Raghy, S. M.
- Published
- 2023
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24. The Clinical Impact of Paravalvular Leaks With Transcutaneous Aortic Valve Implantation (TAVI) Versus Surgical Aortic Valve Replacement (SAVR): A Systematic Review and Meta-Analysis
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Moawad, Karim R., primary, Mohamed, Saifullah, additional, Hammad, Alaa, additional, and Barker, Thomas, additional
- Published
- 2024
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25. Snow crystal-like structure of NiSe as a binder-free electrode for high-performance hybrid supercapacitor
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Bekhit, Samah M., Mohamed, Saad G., Ghayad, Ibrahim M., Attia, Sayed Y., Metwally, W., Abdel-Karim, R., and El-Raghy, S. M.
- Published
- 2022
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26. Incentives for public goods inside organizations: Field experimental evidence
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Blasco, Andrea, Jung, Olivia S, Lakhani, Karim R, and Menietti, Michael
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Economics ,Commerce ,Management ,Tourism and Services ,Economic Theory ,Strategy ,Management and Organisational Behaviour ,Clinical Research ,Innovation contests ,Relative incentives ,Organizational improvement ,Free rider problem ,Social incentives ,Organization of work ,Healthcare organization ,Applied Economics ,Econometrics ,Banking ,finance and investment ,Applied economics - Published
- 2019
27. Nickel selenide nanorod arrays as an electrode material for lithium-ion batteries and supercapacitors
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Bekhit, Samah M., Mohamed, Saad G., Ghayad, Ibrahim M., Fayed, Moataz G., Metwally, W., Abdel-Karim, R., and El-Raghy, S.M.
- Published
- 2022
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28. How status of research papers affects the way they are read and cited
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Teplitskiy, Misha, Duede, Eamon, Menietti, Michael, and Lakhani, Karim R.
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- 2022
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29. The Crowdless Future? Generative AI and Creative Problem-Solving.
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Boussioux, Léonard, Lane, Jacqueline N., Zhang, Miaomiao, Jacimovic, Vladimir, and Lakhani, Karim R.
- Subjects
GENERATIVE artificial intelligence ,LANGUAGE models ,TEACHER development ,CIRCULAR economy ,BUSINESS schools - Abstract
The rapid advances in generative artificial intelligence (AI) open up attractive opportunities for creative problem-solving through human-guided AI partnerships. To explore this potential, we initiated a crowdsourcing challenge focused on sustainable, circular economy business ideas generated by the human crowd (HC) and collaborative human-AI efforts using two alternative forms of solution search. The challenge attracted 125 global solvers from various industries, and we used strategic prompt engineering to generate the human-AI solutions. We recruited 300 external human evaluators to judge a randomized selection of 13 out of 234 solutions, totaling 3,900 evaluator-solution pairs. Our results indicate that while human crowd solutions exhibited higher novelty—both on average and for highly novel outcomes—human-AI solutions demonstrated superior strategic viability, financial and environmental value, and overall quality. Notably, human-AI solutions cocreated through differentiated search, where human-guided prompts instructed the large language model to sequentially generate outputs distinct from previous iterations, outperformed solutions generated through independent search. By incorporating "AI in the loop" into human-centered creative problem-solving, our study demonstrates a scalable, cost-effective approach to augment the early innovation phases and lays the groundwork for investigating how integrating human-AI solution search processes can drive more impactful innovations. Funding: This work was supported by Harvard Business School (Division of Research and Faculty Development) and the Laboratory for Innovation Science at Harvard (LISH) at the Digital Data and Design (D
3 ) Institute at Harvard. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.18430. [ABSTRACT FROM AUTHOR]- Published
- 2024
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30. Recent Trends and Developments in the Electrical Discharge Machining Industry: A Review
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Anna A. Kamenskikh, Karim R. Muratov, Evgeny S. Shlykov, Sarabjeet Singh Sidhu, Amit Mahajan, Yulia S. Kuznetsova, and Timur R. Ablyaz
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EDM ,workpiece ,electrode tool (ET) ,dielectric ,technology ,statistics ,Production capacity. Manufacturing capacity ,T58.7-58.8 - Abstract
Electrical discharge machining (EDM) is a highly precise technology that not only facilitates the machining of components into desired shapes but also enables the alteration of the physical and chemical properties of workpieces. The complexity of the process is due to a number of regulating factors such as the material of the workpiece and tools, dielectric medium, and other process parameters. Based on the material type, electrode shape, and process configuration, various shapes and degrees of accuracy can be generated. The study of erosion is based on research into processing techniques, which are the primary tools for using EDM. Empirical knowledge with subsequent optimization of technological parameters is one of the ways to obtain the required surface quality of the workpiece with defect minimization, as well as mathematical and numerical modeling of the EDM process. This article critically examines all key aspects of EDM, reflecting both the early foundations of electrical erosion and the current state of the industry, noting the current trends towards the transition of EDM to the 5.0 industry zone in terms of safety and minimizing the impact of the process on the environment.
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- 2023
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31. Microporous Block Copolymers Modified with Cu(II)-Coordinated Polyethylene Oxide-Substituted Silicas for Analytical Sensors
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Ilsiya M. Davletbaeva, Ekaterina D. Li, Zulfiya Z. Faizulina, Oleg O. Sazonov, Oleg V. Mikhailov, Karim R. Safiullin, and Ruslan S. Davletbaev
- Subjects
block copolymers ,modification ,Cu(II)-coordinated polyoxyethylene-substituted silicas ,sorption activity ,analytical test systems ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
The influence of stable-to-self-condensation Cu(II)-coordinated polyoxyethylene-substituted silicas (ASiP-Cu-0.5) on the synthesis of microporous block copolymers (OBCs) whose structural feature is the existence of coplanar polyisocyanate blocks of acetal nature (O-polyisocyanates) and a flexible-chain component of amphiphilic nature was studied. The use of ASiP-Cu-0.5 increased the yield of O-polyisocyanate blocks and the microphase separation of OBC. The resulting OBCs turned out to be effective sorbents for the analytical reagents PAN and PHENAZO, which, being in the micropore cavity, interacted with copper(II) and magnesium ions. To reduce the thickness of the selective OBC layer ten-fold and simplify the technology for obtaining analytical test systems, polyethylene terephthalate was used as a substrate for applying OBC. It was found that the increased sensitivity of the resulting test systems was due to the fact that in thin reaction layers, the efficiency of the formation of O-polyisocyanate blocks noticeably increased.
- Published
- 2023
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32. Electrochemical behavior of Ni–Cu foams fabricated by dynamic hydrogen bubble template electrodeposition used for energy applications
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Reda, Y., Abdel-Karim, R., Zohdy, K.M., and El-Raghy, S.
- Published
- 2022
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33. Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response
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Botson, John K., Baraf, Herbert S. B., Keenan, Robert T., Albert, John, Masri, Karim R., Peterson, Jeff, Yung, Christianne, Freyne, Brigid, Amin, Mona, Abdellatif, Abdul, Soloman, Nehad, Edwards, N. Lawrence, and Strand, Vibeke
- Published
- 2022
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34. Effect of Fenugreek Seeds in Maternal Diet on Some Features of Newborn Pups in Albino Mice
- Author
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Karim R. Hamad
- Subjects
fenugreek ,body weight ,litter size ,sex ratio ,endometrial glands ,Science - Abstract
Fenugreek seeds have got interest of researchers for their positive effects on laboratory animals and human being, including their effects on reproductive system. The present study aimed to investigate the effects of 5% raw fenugreek seed and its boiled aqueous extract containing diet on adult female mice, for 2 weeks before mating, to evaluate fertility, and some features of newborn pups. Materials and Methods: A total of 90 adult female mice randomly and equally were divided into three groups. Group I: Control, Group II: Female mice treated with 5% raw fenugreek seed containing diet, and Group III: Female mice treated with boiled aqueous extract of 5% fenugreek seed containing diet. The animals were treated daily for 2 weeks before mating. Some of them were mated with normal males, while the others were used for uterus study. The following parameters were evaluated: Fertility of adult female mice; body weight (BW); uterus weight; uterus sections; litter size; sex ratio; live and dead pups; and pup BW. Results: There was non-significant change in litter size and sex ratio; live and dead pups; adult female BW; and uterus weight. While wet and dry weight of pups, were significantly increased. Histological sections in uterus showed multilayering in endometrial glands of both the experimental groups. No differences were observed between fenugreek treated groups. Conclusion: Both forms of fenugreek seed (raw and aqueous extract) induced significant increase in pup weight; possibly are due to multilayering in endometrial glands of uterus.
- Published
- 2021
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35. Physicochemical properties, urocanic acid and biogenic amine contents of black pomfret (Parastromateus niger) as affected by fermentation times
- Author
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Azman, E.M., primary, Zare, D., additional, Y., Nurhayati, additional, Karim, R., additional, and Ghazali, H.M., additional
- Published
- 2024
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36. Dynamic Radiographs Are Unreliable to Assess Arthrodesis Following Cervical Fusion: A Modeled Radiostereometric Analysis of Cervical Motion
- Author
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Pinter, Zachariah W., Skjaerlund, Jonathan, Michalopoulos, Giorgos D., Nathani, Karim R., Bydon, Mohamad, Nassr, Ahmad, Sebastian, Arjun S., and Freedman, Brett A.
- Published
- 2023
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37. Formation of the roughness during honing with raster kinematics of the tool
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Muratov, Karim R., Gashev, Evgeniy A., Ablyaz, Timur R., and Sidhu, Sarabjeet S.
- Published
- 2021
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38. Influence of discharge energy on the properties steel alloy after EDM
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Ablyaz, Timur R., Sidhu, Sarabjeet S., Shlykov, Evgeny S., and Muratov, Karim R.
- Published
- 2021
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39. Physicochemical properties, urocanic acid and biogenic amine contents of black pomfret (Parastromateus niger) as affected by fermentation times
- Author
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M. Azman, E., Zare, D., Nurhayati, Y., Karim, R., Ghazali, H. M., M. Azman, E., Zare, D., Nurhayati, Y., Karim, R., and Ghazali, H. M.
- Abstract
Fermented freshwater and marine products are popular in Malaysia and among these is ikan pekasam (fermented fish). It is typically made from freshwater fish with groundroasted rice as the main source of carbohydrate during fermentation. In this study, rather than freshwater fish, black pomfret (Parastromateus niger), a marine fish, was used to produce ikan pekasam. Black pomfret was mixed with 3 kg of ground roasted rice and 10% (v/w of fish) water and allowed to ferment for 2 and 5 weeks at 25 – 30°C. Then, fermented black pomfret was analysed for its physicochemical properties, compositions of biogenic amine, urocanic acid (UCA) and organic acid, as well as sensory acceptability. The pH and titratable acidity significantly (p ≤ 0.05) decreased and increased, respectively, after 5 weeks of fermentation due to the increase in organic acids, mainly lactic acid. Histamine, putrescine, cadaverine and 2-phenylethylamine increased rapidly after 5 weeks of fermentation but histamine was within the recommended level (50 mg/kg; US Food and Drug Administration (USFDA)). The strong correlation between trans- and cis-urocanic acid indicated that photoisomerization of trans-UCA into cis-UCA occurred. Overall, principal component analysis (PCA) revealed that the two-week fermented black pomfret was more acceptable to the consumer panellists than the five-week due to its acceptable aroma, saltiness, sourness and texture. Notably, this two-week sample had significantly (p ≤ 0.05) lower biogenic amine and UCA contents; suggesting a safer and good quality of ikan pekasam.
- Published
- 2024
40. MULTIVARIATE STATISTICAL TECHNIQUES OF WATER QUALITY IN TIGRIS RIVER WITHIN BAGHDAD CITY
- Author
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Noor Q. Ahmed and Karim R. Gubashi
- Subjects
statistical analysis ,quality index ,water quality ,factor analysis ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
This study was conducted to assess the water quality of Tigris River within Baghdad city by using Weighted Arithmetic model. The studay area included five sites: Thiraa-Tigris (S1), Al-Muthana bridge (S2), Al-Shuhadaa bridge (S3), Al-Doraa (S4) and confluence point of the Diyala river (S5). Ten water quality parameters were used in this study, Total Hardness (TH), Calcium (Ca), Hydrogen Ion concentration (pH), Chloride (Cl), Magnesium (Mg), Nitrate (NO3), Sodium (Na), Boron (B), Turbidity (TUR) and Sulfate (SO4). Statistical analysis such as correlation and regression coefficient using the statistical program SPSS was used to evaluate the results of the water quality index as well as to find a relationship between the water quality index and the variables. Several statistical methods, Factor Analysis (FA), Principal Component Analysis (PCA), Discriminant Analysis (DA), and Time Series Analysis assess parameters affecting water quality during the study period (August-December) 2019. The results showed Poor to Unsuitable quality index in Tigris River at Baghdad city except for Al-Muthna Bridge (S2) was grade good quality index during the time. From the analysis, that the worst water quality index was found at confluence place of Diyala River (S5) and grade unsuitable quality index.
- Published
- 2021
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41. The Price of Anarchy of Self-Selection in Tullock Contests.
- Author
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Hau Chan, David C. Parkes, and Karim R. Lakhani
- Published
- 2020
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42. Efficient synthesis of tricaproin: catalyst and reaction optimization.
- Author
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Musin, Lenar I., Akhmadullin, Renat M., Gizutdinov, Karim R., Nigmatullina, Lilya Sh., Lopukhov, Leonid V., Zaripova, Anna N., Nigamatullin, Dinar D., Spiryagin, Valerii V., Le, Huu Quynh Anh, Pham, Thi Nam, Dao, My Uyen, Lai, Hong Dung, and Hoang, Hien Y
- Subjects
CATALYST poisoning ,PHOSPHORIC acid ,MASS spectrometry ,ESTERIFICATION ,CATALYST synthesis - Abstract
This study presents a short communication on exploring, for the first time, a simple approach for the selective and highly effective synthesis of tricaproin by synergistically combining silicon tripolyphosphate and phosphoric acid in the catalytic esterification of glycerol with caproic acid. Results reveal that within the initial hour of the synthesis, the conversion in the presence of the proposed mixture achieved an efficiency of 62.99 %, whereas this figure for individual catalysts only modestly stopped at 27.50 and 11.74 %, respectively. Furthermore, the inherent shortcomings in the tricaprion synthesis, such as catalyst deactivation, resinification of the reaction solution, and generation of numerous by-products, were successfully addressed. The structure of the resultant tricaproin and the possible absence of undesired by-products were confirmed by NMR, mass spectrometry, FT-IR, and TLC. The optimal conditions for the synthesis were also investigated. The study not only contributes a practical and selective synthetic approach for tricaproin but also paves the way for exploring novel avenues to enhance the efficiency of the catalytic esterification. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
43. Collective Creativity and Innovation: An Interdisciplinary Review, Integration, and Research Agenda.
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Acar, Oguz A., Tuncdogan, Aybars, van Knippenberg, Daan, and Lakhani, Karim R.
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INNOVATIONS in business ,CREATIVE ability ,TEAMS in the workplace ,COOPERATION ,COGNITION ,SOCIAL factors ,ORGANIZATIONAL structure - Abstract
Collective creativity and innovation are key determinants of various important outcomes ranging from competitiveness of an organization to GDP growth of a country. As a result, this topic has attracted widespread scholarly interest from different disciplines, including strategic management, entrepreneurship, production and operations management, information systems, marketing, organizational behavior, sociology, economics, and psychology. However, this research remained isolated within disciplinary boundaries, which presents a major barrier for knowledge accumulation and cross-disciplinary learning. In this review, building on a new taxonomy of collectivity, we develop an integrative framework that organizes and synthesizes the fragmented research on the topic. The framework shows how antecedents related to the cognitive, social, and organizational architecture of a collective impact innovation depending on the collectivity type: attention-based, divergence-based, and convergence-based collectives. As a whole, our framework builds an integrative understanding of drivers of collective creativity and innovation and sets the stage for further theory development by facilitating communication across different disciplines. We conclude our review with an agenda for future research. [ABSTRACT FROM AUTHOR]
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- 2024
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44. Treatment Patterns and Effectiveness of Tofacitinib in Patients Initiating Therapy for Rheumatoid Arthritis: Results from the CorEvitas Rheumatoid Arthritis Registry
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Pappas, Dimitrios A., primary, O'Brien, Jacqueline, additional, Moore, Page C., additional, Dodge, Rhiannon, additional, Germino, Rebecca, additional, Masri, Karim R., additional, Bingham, Clifton O., additional, and Cappelli, Laura C., additional
- Published
- 2024
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- View/download PDF
45. A295 A CHALLENGING DIAGNOSTIC CASE - SEVERE ACUTE HEPATITIS POTENTIALLY ASSOCIATED WITH COVID-19 IN AN IMMUNOCOMPETENT YOUNG ADULT
- Author
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Lawendy, B, primary, Hudson, D, additional, and Abdul-Karim, R, additional
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- 2024
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46. Don't Expect Juniors to Teach Senior Professionals to Use Generative AI: Emerging Technology Risks and Novice AI Risk Mitigation Tactics
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Kellogg, Katherine, primary, Lifshitz-Assaf, Hila, additional, Randazzo, Steven, additional, Mollick, Ethan R., additional, Dell'Acqua, Fabrizio, additional, McFowland III, Edward, additional, Candelon, Francois, additional, and Lakhani, Karim R., additional
- Published
- 2024
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47. The occurrence and density of some molluscs species in different areas of Basrah province, southern of Iraq and first record of The invasive golden mussel Limnoperna fortunei (Dunker, 1857)
- Author
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Al-Khafaji, K. K., primary, Al-Baghdadi, N. M., additional, Alwaeli, A. A. A., additional, and Karim, R. M., additional
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- 2024
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48. Highly efficient phosphine-catalyzed routes to α-imidoacrylates and 2,3-diimidopropanoates
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Il’in, Anton V., Gubaev, Arthur F., Islamov, Daut R., Islamov, Karim R., and Galkin, Vladimir I.
- Published
- 2021
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49. Hibernoma: a case report of a rare cardiac tumour
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Cistulli, D, primary, Othman, F, additional, Karim, R, additional, and Puranik, R, additional
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- 2023
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50. Detecting Figures and Part Labels in Patents: Competition-Based Development of Image Processing Algorithms
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Riedl, Christoph, Zanibbi, Richard, Hearst, Marti A., Zhu, Siyu, Menietti, Michael, Crusan, Jason, Metelsky, Ivan, and Lakhani, Karim R.
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Information Retrieval - Abstract
We report the findings of a month-long online competition in which participants developed algorithms for augmenting the digital version of patent documents published by the United States Patent and Trademark Office (USPTO). The goal was to detect figures and part labels in U.S. patent drawing pages. The challenge drew 232 teams of two, of which 70 teams (30%) submitted solutions. Collectively, teams submitted 1,797 solutions that were compiled on the competition servers. Participants reported spending an average of 63 hours developing their solutions, resulting in a total of 5,591 hours of development time. A manually labeled dataset of 306 patents was used for training, online system tests, and evaluation. The design and performance of the top-5 systems are presented, along with a system developed after the competition which illustrates that winning teams produced near state-of-the-art results under strict time and computation constraints. For the 1st place system, the harmonic mean of recall and precision (f-measure) was 88.57% for figure region detection, 78.81% for figure regions with correctly recognized figure titles, and 70.98% for part label detection and character recognition. Data and software from the competition are available through the online UCI Machine Learning repository to inspire follow-on work by the image processing community.
- Published
- 2014
- Full Text
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