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3. The efficacy of the TRK inhibitor entrectinib in patients with extracranial NTRK fusion-positive tumors

Author

Stradomskaya, T. V., primary, Suleymanova, A. M., additional, Konovalov, D. M., additional, Druy, A. E., additional, Panfyorova, A. V., additional, Preobrazhenskaya, E. V., additional, Andreeva, N. A., additional, Sagoyan, G. B., additional, Teleshova, M. V., additional, Smirnova, L. A., additional, Zacarinnaya, O. S., additional, Shamanskaya, T. V., additional, Grachev, N. S., additional, Rubanskaya, M. V., additional, Kirgizov, K. I., additional, Imyanitov, E. N., additional, Varfolomeeva, S. R., additional, and Kachanov, D. Yu., additional

Published
2023
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5. Consensus on the diagnosis and treatment of PROS (PIK3CA-related overgrowth spectrum). Russian version

Author

Sagoyan, G. B., primary, Zhukov, N. V., additional, Strelnikov, V. V., additional, Khagurov, R. A., additional, Suleymanova, A. M., additional, Mareeva, Yu. M., additional, Garbuzov, R. V., additional, Imyanitov, E. N., additional, Dinikina, Yu. V., additional, Kutsev, S. I., additional, Donyush, E. K., additional, Kirgizov, K. I., additional, Semenova, N. A., additional, Polyaev, Yu. A., additional, Kletskaya, I. S., additional, Maschan, A. A., additional, and Varfolomeeva, S. R., additional

Published
2023
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6. Haematopoietic stem cell transplantation for severe autoimmune diseases in children: A review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation

Author

Achini-Gutzwiller, F, Snowden, J, Corbacioglu, S, Greco, R, Alexander, T, Badoglio, M, Labopin, M, Abinun, M, Apte, S, Arnold, R, Domenech, A, Brierley, C, Burman, J, Castilla-Llorente, C, Cooper, N, Daghia, G, Daikeler, T, del Papa, N, de Vries-Bouwstra, J, Farge, D, Finke, J, Hagglund, H, Hawkey, C, Henes, J, Hiepe, F, Jessop, H, Kiely, D, Kazmi, M, Kirgizov, K, Kramer, E, Mancardi, G, Marjanovic, Z, Martin, R, Martin, T, Ma, D, Moore, J, Miller, P, Muraro, P, Oliveira, M, Polushin, A, Onida, F, Simoes, B, Puyade, M, Resnick, I, Ricart, E, Rovira, M, Saccardi, R, Saif, M, Sakellari, I, Sharrack, B, Snarski, E, Scherer, H, Sossa, C, Withers, B, Wulffraat, N, Zaccara, E, Amrolia, P, Ansari, M, Balduzzi, A, Dalassier, A, Dalle, J, Diaz, C, Feuchtinger, T, Locatelli, F, Lucchini, G, Galimard, J, Vincent, M, Handgretinger, R, Kleinschmidt, K, Lawitschka, A, Martinez, A, Peters, C, Rocha, V, Ruggeri, A, Sedlacek, P, Svec, P, Toporski, J, Yesilipek, A, Achini-Gutzwiller F. R., Snowden J. A., Corbacioglu S., Greco R., Alexander T., Snowden J., Badoglio M., Labopin M., Abinun M., Apte S., Arnold R., Domenech A., Brierley C., Burman J., Castilla-Llorente C., Cooper N., Daghia G., Daikeler T., del Papa N., de Vries-Bouwstra J., Farge D., Finke J., Hagglund H., Hawkey C., Henes J., Hiepe F., Jessop H., Kiely D., Kazmi M., Kirgizov K., Kramer E., Mancardi G., Marjanovic Z., Martin R., Martin T., Ma D., Moore J., Miller P., Muraro P., Oliveira M. -C., Polushin A., Onida F., Simoes B., Puyade M., Resnick I., Ricart E., Rovira M., Saccardi R., Saif M., Sakellari I., Sharrack B., Snarski E., Scherer H. U., Sossa C., Withers B., Wulffraat N., Zaccara E., Amrolia P., Ansari M., Balduzzi A., Dalassier A., Dalle J. -H., Diaz C. H., Feuchtinger T., Locatelli F., Lucchini G., Galimard J. -E., Vincent M. G., Handgretinger R., Kleinschmidt K., Lawitschka A., Martinez A. P., Peters C., Rocha V., Ruggeri A., Sedlacek P., Svec P., Toporski J., Yesilipek A., Achini-Gutzwiller, F, Snowden, J, Corbacioglu, S, Greco, R, Alexander, T, Badoglio, M, Labopin, M, Abinun, M, Apte, S, Arnold, R, Domenech, A, Brierley, C, Burman, J, Castilla-Llorente, C, Cooper, N, Daghia, G, Daikeler, T, del Papa, N, de Vries-Bouwstra, J, Farge, D, Finke, J, Hagglund, H, Hawkey, C, Henes, J, Hiepe, F, Jessop, H, Kiely, D, Kazmi, M, Kirgizov, K, Kramer, E, Mancardi, G, Marjanovic, Z, Martin, R, Martin, T, Ma, D, Moore, J, Miller, P, Muraro, P, Oliveira, M, Polushin, A, Onida, F, Simoes, B, Puyade, M, Resnick, I, Ricart, E, Rovira, M, Saccardi, R, Saif, M, Sakellari, I, Sharrack, B, Snarski, E, Scherer, H, Sossa, C, Withers, B, Wulffraat, N, Zaccara, E, Amrolia, P, Ansari, M, Balduzzi, A, Dalassier, A, Dalle, J, Diaz, C, Feuchtinger, T, Locatelli, F, Lucchini, G, Galimard, J, Vincent, M, Handgretinger, R, Kleinschmidt, K, Lawitschka, A, Martinez, A, Peters, C, Rocha, V, Ruggeri, A, Sedlacek, P, Svec, P, Toporski, J, Yesilipek, A, Achini-Gutzwiller F. R., Snowden J. A., Corbacioglu S., Greco R., Alexander T., Snowden J., Badoglio M., Labopin M., Abinun M., Apte S., Arnold R., Domenech A., Brierley C., Burman J., Castilla-Llorente C., Cooper N., Daghia G., Daikeler T., del Papa N., de Vries-Bouwstra J., Farge D., Finke J., Hagglund H., Hawkey C., Henes J., Hiepe F., Jessop H., Kiely D., Kazmi M., Kirgizov K., Kramer E., Mancardi G., Marjanovic Z., Martin R., Martin T., Ma D., Moore J., Miller P., Muraro P., Oliveira M. -C., Polushin A., Onida F., Simoes B., Puyade M., Resnick I., Ricart E., Rovira M., Saccardi R., Saif M., Sakellari I., Sharrack B., Snarski E., Scherer H. U., Sossa C., Withers B., Wulffraat N., Zaccara E., Amrolia P., Ansari M., Balduzzi A., Dalassier A., Dalle J. -H., Diaz C. H., Feuchtinger T., Locatelli F., Lucchini G., Galimard J. -E., Vincent M. G., Handgretinger R., Kleinschmidt K., Lawitschka A., Martinez A. P., Peters C., Rocha V., Ruggeri A., Sedlacek P., Svec P., Toporski J., and Yesilipek A.

Abstract

Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over recent decades, a proportion will experience ongoing or recurrent/relapsing disease activity despite multiple therapies often leading to irreversible organ damage, and compromised quality of life, growth/development and long-term survival. Autologous and allogeneic haematopoietic stem cell transplantation (HSCT) have been used successfully to induce disease control and often apparent cure of severe treatment-refractory autoimmune diseases (ADs) in children. However, transplant-related outcomes are disease-dependent and long-term outcome data are limited in respect to efficacy and safety. Moreover, balancing risks of HSCT against AD prognosis with continually evolving non-transplant options is challenging. This review appraises published literature on HSCT strategies and outcomes in individual paediatric ADs. We also provide a summary of the European Society for Blood and Marrow Transplantation (EBMT) Registry, where 343 HSCT procedures (176 autologous and 167 allogeneic) have been reported in 326 children (<18 years) for a range of AD indications. HSCT is a promising treatment modality, with potential long-term disease control or cure, but therapy-related morbidity and mortality need to be reduced. Further research is warranted to establish the position of HSCT in paediatric ADs via registries and prospective clinical studies to support evidence-based interspeciality guidelines and recommendations.

Published
2022

7. Results of hematopoietic stem cell transplantation in children with acute leukemia: a single-center experience

Author

Kostareva, I. O., primary, Kirgizov, K. I., additional, Machneva, E. B., additional, Aliev, T. Z., additional, Lozovan, Yu. V., additional, Sergeenko, K. A., additional, Burlaka, N. A., additional, Potemkina, T. I., additional, Mitrakov, K. V., additional, Yelfimova, A. Yu., additional, Slinin, A. S., additional, Malova, M. D., additional, Fatkhullin, R. R., additional, Stepanyan, N. G., additional, Batmanova, N. A., additional, Valiev, T. T., additional, and Varfolomeeva, S. R., additional

Published
2023
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8. Modern methods of therapy in the development of life-threatening complications in a patient after repeated allogeneic hematopoietic stem cell transplantation: review of the literature and clinical case

Author

Sergeenko, K. A., primary, Machneva, E. B., additional, Aliev, T. Z., additional, Kostareva, I. O., additional, Valiev, T. T., additional, Kiselevskiy, M. V., additional, Vlasenko, R. Ya., additional, Kirgizov, K. I., additional, and Varfolomeeva, S. R., additional

Published
2023
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10. Haematopoietic stem cell transplantation for severe autoimmune diseases in children : a review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation

Author

Achini‐Gutzwiller, FR, Snowden, JA, Corbacioglu, S, Greco, R, Alexander, T, Snowden, J, Badoglio, M, Labopin, M, Abinun, M, Apte, S, Arnold, R, Domenech, A, Brierley, C, Burman, J, Castilla‐Llorente, C, Cooper, N, Daghia, G, Daikeler, T, del Papa, N, de Vries‐Bouwstra, J, Farge, D, Finke, J, Hagglund, H, Hawkey, C, Henes, J, Hiepe, F, Jessop, H, Kiely, D, Kazmi, M, Kirgizov, K, Kramer, E, Mancardi, G, Marjanovic, Z, Martin, R, Martin, T, Ma, D, Moore, J, Miller, P, Muraro, P, Oliveira, M, Polushin, A, Onida, F, Simoes, B, Puyade, M, Resnick, I, Ricart, E, Rovira, M, Saccardi, R, Saif, M, Sakellari, I, Sharrack, B, Snarski, E, Scherer, HU, Sossa, C, Withers, B, Wulffraat, N, Zaccara, E, Amrolia, P, Ansari, M, Balduzzi, A, Dalassier, A, Dalle, J, Diaz, CH, Feuchtinger, T, Locatelli, F, Lucchini, G, Galimard, J, Vincent, MG, Handgretinger, R, Kleinschmidt, K, Lawitschka, A, Martinez, AP, Peters, C, Rocha, V, Ruggeri, A, Sedlacek, P, Svec, P, Toporski, J, Yesilipek, A, Achini-Gutzwiller, F, Snowden, J, Corbacioglu, S, Greco, R, Alexander, T, Badoglio, M, Labopin, M, Abinun, M, Apte, S, Arnold, R, Domenech, A, Brierley, C, Burman, J, Castilla-Llorente, C, Cooper, N, Daghia, G, Daikeler, T, del Papa, N, de Vries-Bouwstra, J, Farge, D, Finke, J, Hagglund, H, Hawkey, C, Henes, J, Hiepe, F, Jessop, H, Kiely, D, Kazmi, M, Kirgizov, K, Kramer, E, Mancardi, G, Marjanovic, Z, Martin, R, Martin, T, Ma, D, Moore, J, Miller, P, Muraro, P, Oliveira, M, Polushin, A, Onida, F, Simoes, B, Puyade, M, Resnick, I, Ricart, E, Rovira, M, Saccardi, R, Saif, M, Sakellari, I, Sharrack, B, Snarski, E, Scherer, H, Sossa, C, Withers, B, Wulffraat, N, Zaccara, E, Amrolia, P, Ansari, M, Balduzzi, A, Dalassier, A, Dalle, J, Diaz, C, Feuchtinger, T, Locatelli, F, Lucchini, G, Galimard, J, Vincent, M, Handgretinger, R, Kleinschmidt, K, Lawitschka, A, Martinez, A, Peters, C, Rocha, V, Ruggeri, A, Sedlacek, P, Svec, P, Toporski, J, and Yesilipek, A

Subjects
autoimmune diseases, haematopoietic stem cell transplantation, paediatric, ddc:610, paediatric, surgical procedures, operative, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, haematopoietic stem cell transplantation, 610 Medizin, autoimmune diseases, autoimmune disease, Hematology
Abstract

Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over recent decades, a proportion will experience ongoing or recurrent/relapsing disease activity despite multiple therapies often leading to irreversible organ damage, and compromised quality of life, growth/development and long-term survival. Autologous and allogeneic haematopoietic stem cell transplantation (HSCT) have been used successfully to induce disease control and often apparent cure of severe treatment-refractory autoimmune diseases (ADs) in children. However, transplant-related outcomes are disease-dependent and long-term outcome data are limited in respect to efficacy and safety. Moreover, balancing risks of HSCT against AD prognosis with continually evolving non-transplant options is challenging. This review appraises published literature on HSCT strategies and outcomes in individual paediatric ADs. We also provide a summary of the European Society for Blood and Marrow Transplantation (EBMT) Registry, where 343 HSCT procedures (176 autologous and 167 allogeneic) have been reported in 326 children (

Published
2022

14. Hematopoietic stimulants in the treatment and prevention of graft-versus-host disease

Author

Shirin, A. D., primary, Vlasenko, R. Ya., additional, Anisimova, N. Yu., additional, Kirgizov, K. I., additional, Valiev, T. T., additional, Stepanyan, N. G., additional, Aliev, T. Z., additional, Morozevich, G. E., additional, Odaryuk, O. A., additional, Filonenko, D. V., additional, Nifantiev, N. E., additional, Novruzov, K. M., additional, Chikileva, I. O., additional, and Kiselevskiy, M. V., additional

Published
2023
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17. Pediatric acute lymphoblastic leukemia: multicenter study of the treatment by the protocol ALL IC-BFM 2002

Author

Valiev, T. T., primary, Shervashidze, M. A., additional, Osipova, I. V., additional, Burlutskaya, T. I., additional, Popova, N. A., additional, Osmulskaya, N. S., additional, Aleskerova, G. A., additional, Sabantsev, S. L., additional, Gordeeva, Z. S., additional, Smirnov, V. Yu., additional, Poberezhnaya, O. A., additional, Yuldasheva, S. N., additional, Babich, I. A., additional, Guseynov, V. T., additional, Jalilova, S. N., additional, Korkina, Yu. S., additional, Batmanova, N. A., additional, Kirgizov, K. I., additional, and Varfolomeeva, S. R., additional

Published
2022
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18. The use of multistage immunotherapy to achieve remission before haploidentical hematopoietic stem cell transplantation in patients with acute lymphoblastic leukemia and the treatment of complications of this therapy in the early post-transplant period: a review of the literature and a clinical case

Author

Sergeenko, K. A., primary, Aliev, T. Z., additional, Kostareva, I. O., additional, Lozovan, Yu. V., additional, Malova, M. D., additional, Batmanova, N. A., additional, Valiev, T. T., additional, Machneva, E. B., additional, and Kirgizov, K. I., additional

Published
2022
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19. Haematopoietic stem cell transplantation for severe autoimmune diseases in children: A review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation

Author

Achini-Gutzwiller, F. R., Snowden, J. A., Corbacioglu, S., Greco, R., Alexander, T., Snowden, J., Badoglio, M., Labopin, M., Abinun, M., Apte, S., Arnold, R., Domenech, A., Brierley, C., Burman, J., Castilla-Llorente, C., Cooper, N., Daghia, G., Daikeler, T., del Papa, N., de Vries-Bouwstra, J., Farge, D., Finke, J., Hagglund, H., Hawkey, C., Henes, J., Hiepe, F., Jessop, H., Kiely, D., Kazmi, M., Kirgizov, K., Kramer, E., Mancardi, G., Marjanovic, Z., Martin, R., Martin, T., Ma, D., Moore, J., Miller, P., Muraro, P., Oliveira, M. -C., Polushin, A., Onida, F., Simoes, B., Puyade, M., Resnick, I., Ricart, E., Rovira, M., Saccardi, R., Saif, M., Sakellari, I., Sharrack, B., Snarski, E., Scherer, H. U., Sossa, C., Withers, B., Wulffraat, N., Zaccara, E., Amrolia, P., Ansari, M., Balduzzi, A., Dalassier, A., Dalle, J. -H., Diaz, C. H., Feuchtinger, T., Locatelli, Franco, Lucchini, G., Galimard, J. -E., Vincent, M. G., Handgretinger, R., Kleinschmidt, K., Lawitschka, A., Martinez, A. P., Peters, C., Rocha, V., Ruggeri, A., Sedlacek, P., Svec, P., Toporski, J., Yesilipek, A., Locatelli F. (ORCID:0000-0002-7976-3654), Achini-Gutzwiller, F. R., Snowden, J. A., Corbacioglu, S., Greco, R., Alexander, T., Snowden, J., Badoglio, M., Labopin, M., Abinun, M., Apte, S., Arnold, R., Domenech, A., Brierley, C., Burman, J., Castilla-Llorente, C., Cooper, N., Daghia, G., Daikeler, T., del Papa, N., de Vries-Bouwstra, J., Farge, D., Finke, J., Hagglund, H., Hawkey, C., Henes, J., Hiepe, F., Jessop, H., Kiely, D., Kazmi, M., Kirgizov, K., Kramer, E., Mancardi, G., Marjanovic, Z., Martin, R., Martin, T., Ma, D., Moore, J., Miller, P., Muraro, P., Oliveira, M. -C., Polushin, A., Onida, F., Simoes, B., Puyade, M., Resnick, I., Ricart, E., Rovira, M., Saccardi, R., Saif, M., Sakellari, I., Sharrack, B., Snarski, E., Scherer, H. U., Sossa, C., Withers, B., Wulffraat, N., Zaccara, E., Amrolia, P., Ansari, M., Balduzzi, A., Dalassier, A., Dalle, J. -H., Diaz, C. H., Feuchtinger, T., Locatelli, Franco, Lucchini, G., Galimard, J. -E., Vincent, M. G., Handgretinger, R., Kleinschmidt, K., Lawitschka, A., Martinez, A. P., Peters, C., Rocha, V., Ruggeri, A., Sedlacek, P., Svec, P., Toporski, J., Yesilipek, A., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over recent decades, a proportion will experience ongoing or recurrent/relapsing disease activity despite multiple therapies often leading to irreversible organ damage, and compromised quality of life, growth/development and long-term survival. Autologous and allogeneic haematopoietic stem cell transplantation (HSCT) have been used successfully to induce disease control and often apparent cure of severe treatment-refractory autoimmune diseases (ADs) in children. However, transplant-related outcomes are disease-dependent and long-term outcome data are limited in respect to efficacy and safety. Moreover, balancing risks of HSCT against AD prognosis with continually evolving non-transplant options is challenging. This review appraises published literature on HSCT strategies and outcomes in individual paediatric ADs. We also provide a summary of the European Society for Blood and Marrow Transplantation (EBMT) Registry, where 343 HSCT procedures (176 autologous and 167 allogeneic) have been reported in 326 children (<18 years) for a range of AD indications. HSCT is a promising treatment modality, with potential long-term disease control or cure, but therapy-related morbidity and mortality need to be reduced. Further research is warranted to establish the position of HSCT in paediatric ADs via registries and prospective clinical studies to support evidence-based interspeciality guidelines and recommendations.

Published
2022

24. Hematopoietic stem cell transplantation for autoimmune diseases in the time of COVID-19: EBMT guidelines and recommendations

Author

Greco, R., Alexander, T., Burman, J., Papa, N. del, Vries-Bouwstra, J. de, Farge, D., Henes, J., Kazmi, M., Kirgizov, K., Muraro, P.A., Ricart, E., Rovira, M., Saccardi, R., Sharrack, B., Snarski, E., Withers, B., Jessop, H., Boglione, C., Kramer, E., Badoglio, M., Labopin, M., Orchard, K., Corbacioglu, S., Ljungman, P., Mikulska, M., Camara, R. de la, Snowden, J.A., European Soc Blood Marrow Transp, Autoimmune Dis Working Party ADWP, Infect Dis Working Party IDWP, Pediat Working Party PWP, Joint Accreditation Comm Int Soc C, EBMT Nurses Grp, and Patient Advocacy Comm

Subjects
Feature, Adult, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Best practice, MEDLINE, Hematopoietic stem cell transplantation, Inflammatory bowel disease, Autoimmune Diseases, 03 medical and health sciences, Rheumatic diseases, 0302 clinical medicine, Pandemic, medicine, Humans, Hematologi, Child, Intensive care medicine, Pandemics, 030203 arthritis & rheumatology, Transplantation, SARS-CoV-2, business.industry, Public health, Hematopoietic Stem Cell Transplantation, COVID-19, Hematology, Infectious diseases, Immunotherapy, business, Neurological disorders, 030217 neurology & neurosurgery
Abstract

Coronavirus disease-19 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), represents one of the biggest challenges of 21st century, threatening public health around the globe. Increasing age and presence of co-morbidities are reported risk factors for severe disease and mortality, along with autoimmune diseases (ADs) and immunosuppressive treatments such as haematopoietic stem cell transplantation (HSCT), which are also associated with adverse outcomes. We review the impact of the pandemic on specific groups of patients with neurological, rheumatological, and gastroenterological indications, along with the challenges delivering HSCT in adult and pediatric populations. Moving forward, we developed consensus-based guidelines and recommendations for best practice and quality of patient care in order to support clinicians, scientists, and their multidisciplinary teams, as well as patients and their carers. These guidelines aim to support national and international organizations related to autoimmune diseases and local clinical teams delivering HSCT. Areas of unmet need and future research questions are also highlighted. The waves of the COVID-19 pandemic are predicted to be followed by an “endemic” phase and therefore an ongoing risk within a “new normality”. These recommendations reflect currently available evidence, coupled with expert opinion, and will be revised according to necessary modifications in practice.

Published
2021

25. Treatment of acute lymphoblastic leukemia in children by ALL IC-BFM 2002 protocol: results of multicenter retrospective study

Author

Valiev, T. T., primary, Shervashidze, M. A., additional, Osipova, I. V., additional, Burlutskaya, T. I., additional, Popova, N. A., additional, Osmulskaya, N. S., additional, Aleskerova, G. A., additional, Sabantsev, S. L., additional, Gordeeva, Z. S., additional, Batmanova, N. A., additional, Trenina, M. R., additional, Birlyukova, D. V., additional, Kirgizov, K. I., additional, and Varfolomeeva, S. R., additional

Published
2021
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30. Treatment of severe infectious complications caused by multidrug-resistant Klebsiella pneumoniae in children with malignant neoplasms of the hematopoietic system: experience of the Research Institute of Pediatric Oncology and Hematology at N.N. Blokhin Russian Cancer Research Center

Author

Sidorova, N. V., primary, Machneva, E. B., additional, Valiev, T. T., additional, Kostareva, I. O., additional, Aliev, T. Z., additional, Elfimova, A. Yu., additional, Lozovan, Yu. V., additional, Pavlova, T. Yu., additional, Korkina, Yu. S., additional, Gorbunova, T. V., additional, Grigorievskaya, Z. V., additional, Petukhova, I. N., additional, Epifanova, N. Yu., additional, and Kirgizov, K. I., additional

Published
2021
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36. BCG vaccine–related complications in patients with primary immunodeficiencies after allogeneic hematopoietic stem cell transplantation

Author

Machneva, E. B., primary, Mezentseva, A. V., additional, Olkhova, L. V., additional, Pristanskova, E. A., additional, Burya, A. E., additional, Konstantinova, V. V., additional, Filina, O. A., additional, Nikolayeva, Yu. A., additional, Svetacheva, A. A., additional, Blagonravova, O. L., additional, Kirgizov, K. I., additional, and Skorobogatova, E. V., additional

Published
2021
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37. Successful use of hydroxymethylquinoxaline dioxide in complex antimicrobial therapy in patients with fulminant infectious complications in induced hematopoesis aplasia by gram-negative agents

Author

Mezentseva, A. V., primary, Olkhova, L. V., additional, Machneva, E. B., additional, Konstantinova, V. V., additional, Burya, A. E., additional, Nikolaeva, Yu. A., additional, Filina, O. A., additional, Purbueva, B. B., additional, Fink, O. S., additional, Antoshin, M. M., additional, Aliev, T. Z., additional, Martynenkova, A. V., additional, Pristanskova, E. A., additional, Sidorova, N. V., additional, Kirgizov, K. I., additional, and Skorobogatova, E. V., additional

Published
2021
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38. Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases : updated guidelines and recommendations from the EBMT autoimmune diseases working party (ADWP) and the joint accreditation committee of EBMT and ISCT (JACIE)

Author

Sharrack, B., Saccardi, R., Alexander, T., Badoglio, M., Burman, J., Farge, D., Greco, R., Jessop, H., Kazmi, M., Kirgizov, K., Labopin, M., Mancardi, G., Martin, R., Moore, J., Muraro, P.A., Rovira, M., Sormani, M.P., and Snowden, J.A.

Subjects
surgical procedures, operative
Abstract

These updated EBMT guidelines review the clinical evidence, registry activity and mechanisms of action of haematopoietic stem cell transplantation (HSCT) in multiple sclerosis (MS) and other immune-mediated neurological diseases and provide recommendations for patient selection, transplant technique, follow-up and future development. The major focus is on autologous HSCT (aHSCT), used in MS for over two decades and currently the fastest growing indication for this treatment in Europe, with increasing evidence to support its use in highly active relapsing remitting MS failing to respond to disease modifying therapies. aHSCT may have a potential role in the treatment of the progressive forms of MS with a significant inflammatory component and other immune-mediated neurological diseases, including chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, myasthenia gravis and stiff person syndrome. Allogeneic HSCT should only be considered where potential risks are justified. Compared with other immunomodulatory treatments, HSCT is associated with greater short-term risks and requires close interspeciality collaboration between transplant physicians and neurologists with a special interest in these neurological conditions before, during and after treatment in accredited HSCT centres. Other experimental cell therapies are developmental for these diseases and patients should only be treated on clinical trials.

Published
2020

46. Results of allogeneic hematopoietic stem cell transplantation in patients with chronic granulomatous disease at the Russian Children’s Clinical Hospital

Author

Machneva, E. B., primary, Pristanskova, E. A., additional, Olkhova, L. V., additional, Mezentseva, A. V., additional, Konstantinova, V. V., additional, Burya, A. E., additional, Blagonravova, O. L., additional, Nikolaeva, Yu. A., additional, Filina, O. A., additional, Sidorova, N. V., additional, Kirgizov, K. I., additional, Vakhlyarskaya, S. S., additional, Kondratenko, I. V., additional, and Skorobogatova, E. V., additional

Published
2020
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47. Chronic “graft versus host” disease after allogeneic hematopoietic stem cell transplantation: basic characteristics, pathogenetic mechanisms, treatment strategies and problems of clinical practice

Author

Machneva, E. B., primary, Panarina, V. Yu., additional, Aliev, T. Z., additional, Shevtsov, D. V., additional, Suleymanova, A. M., additional, Konstantinova, V. V., additional, Burya, A. E., additional, Stepanyan, N. G., additional, Skvortsova, Yu. V., additional, Sidorova, N. V., additional, Osmanov, E. A., additional, Kirgizov, K. I., additional, and Varfolomeeva, S. R., additional

Published
2020
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49. The efficacy of the regimens of “graft versus host” disease prophylaxis after hematopoietic stem cell transplantation from unrelated donors in children: single center experience

Author

Sidorova, N. V., primary, Slinin, A. S., additional, Machneva, E. B., additional, Konstantinova, V. V., additional, Burya, A. E., additional, Pristanskova, E. A., additional, Lagonravova, O. L., additional, Skorobogatovа, E. V., additional, and Kirgizov, K. I., additional

Published
2020
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50. Skin involvement in Burkitt lymphoma: rare clinical case

Author

Valiev, T. T., primary, Matinyan, N. V., additional, Gromova, E. G., additional, Shervashidze, M. A., additional, Tupitsyn, N. N., additional, Zakharova, E. V., additional, Mikhailova, E. V., additional, Kerimov, P. A., additional, Kirgizov, K. I., additional, and Varfolomeeva, S. R., additional

Published
2020
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