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1. Characterization of the cagA-gene in Helicobacter pylori in Mongolia and detection of two EPIYA-A enriched CagA types

Author: Altanbayar, Oyunbaatar, Amgalanbaatar, Avarzed, Battogtokh, Chimeddorj, Bayarjargal, Narmandakh, Belick, Dana, Kohns Vasconcelos, Malte, Mackenzie, Colin R., Pfeffer, Klaus, and Henrich, Birgit
Published: 2022
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2. Interleukin-7 and soluble Interleukin-7 receptor levels in type 1 diabetes – Impact of IL7RA polymorphisms, HLA risk genotypes and clinical features

Author: Hoffmann, Maximilian, Enczmann, Jürgen, Balz, Vera, Kummer, Sebastian, Reinauer, Christina, Döing, Carsten, Förtsch, Katharina, Welters, Alena, Kohns Vasconcelos, Malte, Mayatepek, Ertan, Meissner, Thomas, Jacobsen, Marc, and Seyfarth, Julia
Published: 2022
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3. Profiling of humoral immune responses to norovirus in children across Europe

Author: Villabruna, Nele, Izquierdo-Lara, Ray W., Schapendonk, Claudia M. E., de Bruin, Erwin, Chandler, Felicity, Thao, Tran Thi Nhu, Westerhuis, Brenda M., van Beek, Janko, Sigfrid, Louise, Giaquinto, Carlo, Goossens, Herman, Bielicki, Julia A., Kohns Vasconcelos, Malte, Fraaij, Pieter L. A., Koopmans, Marion P. G., and de Graaf, Miranda
Published: 2022
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4. Searching High and Low: Call for a Joint European Society for Paediatric Infectious Diseases-European Committee on Antimicrobial Susceptibility Testing Survey on Dosage of Antibacterial Agents in Children—Part One

Author: Aguilera-Alonso, David, Cantón, Rafael, Giske, Christian G., Kahlmeter, Gunnar, Kohns Vasconcelos, Malte, Papan, Cihan, and Turnidge, John
Published: 2022
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5. Tuberculosis disease in immunocompromised children and adolescents: a pTBnet multi-centre case-control study

Author: Rodríguez-Molino, Paula, primary, Tebruegge, Marc, additional, Noguera-Julian, Antoni, additional, Neth, Olaf, additional, Fidler, Katy, additional, Brinkmann, Folke, additional, Sainz, Talia, additional, Ivaskeviciene, Inga, additional, Ritz, Nicole, additional, Brito, Maria Joao, additional, Milheiro Silva, Tiago, additional, Chechenieva, Vira, additional, Serdiuk, Maryna, additional, Lancella, Laura, additional, Russo, Cristina, additional, Soler-García, Aleix, additional, Navarro, Maria Luisa, additional, Krueger, Renate, additional, Feiterna-Sperling, Cornelia, additional, Starshinova, Anna, additional, Hiteva, Antonina, additional, Hoffmann, Anna, additional, Kalibatas, Paulius, additional, Lo Vecchio, Andrea, additional, Scarano, Sara Maria, additional, Bustillo, Matilde, additional, Blázquez Gamero, Daniel, additional, Espiau, María, additional, Buonsenso, Danilo, additional, Falcón, Lola, additional, Turnbull, Louise, additional, Colino, Elena, additional, Rueda, Santiago, additional, Buxbaum, Charlotte, additional, Carazo, Begoña, additional, Alvarez, Cristina, additional, Dapena, Marta, additional, Piqueras, Anabel, additional, Velizarova, Svetlana, additional, Ozere, Iveta, additional, Götzinger, Florian, additional, Pareja, Marta, additional, Garrote Llanos, Maria Isabel, additional, Soto, Beatriz, additional, Rodríguez Martín, Sonia, additional, Korta, Jose Javier, additional, Pérez-Gorricho, Beatriz, additional, Herranz, Mercedes, additional, Hernández-Bartolomé, Ángel, additional, Díaz-Almirón, Mariana, additional, Kohns Vasconcelos, Malte, additional, Ferreras-Antolín, Laura, additional, and Santiago-García, Begoña, additional
Published: 2024
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6. SARS-CoV-2 testing and infection control strategies in European paediatric emergency departments during the first wave of the pandemic

Author: Kohns Vasconcelos, Malte, Renk, Hanna, Popielska, Jolanta, Nyirenda Nyang’wa, Maggie, Burokiene, Sigita, Gkentzi, Despoina, Gowin, Ewelina, Donà, Daniele, Villanueva-Medina, Sara, Riordan, Andrew, Hufnagel, Markus, Eisen, Sarah, Da Dalt, Liviana, Giaquinto, Carlo, and Bielicki, Julia A.
Published: 2021
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7. A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

Author: Remppis, Jonathan, Ganzenmueller, Tina, Kohns Vasconcelos, Malte, Heinzel, Oliver, Handgretinger, Rupert, and Renk, Hanna
Published: 2021
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8. Strikingly Decreased Community-acquired Pneumonia Admissions in Children Despite Open Schools and Day-care Facilities in Switzerland

Author: Kohns Vasconcelos, Malte, Meyer Sauteur, Patrick M., Keitel, Kristina, Santoro, Regina, Heininger, Ulrich, van den Anker, John, and Bielicki, Julia A.
Published: 2020
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9. Mycoplasma pneumoniae: gone forever?

Author: Meyer Sauteur, Patrick M, primary, Beeton, Michael L, additional, Pereyre, Sabine, additional, Bébéar, Cécile, additional, Gardette, Marie, additional, Hénin, Nadège, additional, Wagner, Noémie, additional, Fischer, Adrien, additional, Vitale, Alessandra, additional, Kessler, Julie, additional, Andreutti, Corinne, additional, Greub, Gilbert, additional, Zimmermann, Petra, additional, Agyeman, Philipp K A, additional, Aebi, Christoph, additional, Buettcher, Michael, additional, Hostettler, Marisa, additional, Kottanattu, Lisa, additional, Gaia, Valeria, additional, Imkamp, Frank, additional, Egli, Adrian, additional, Berger, Christoph, additional, Sidorov, Semjon, additional, Tilen, Romy, additional, Niederer-Loher, Anita, additional, Barbey, Florence, additional, Heininger, Ulrich, additional, Ivan, Branislav, additional, Papan, Cihan, additional, Becker, Sören L, additional, Forster, Johannes, additional, Kohns Vasconcelos, Malte, additional, Henrich, Birgit, additional, MacKenzie, Colin R, additional, Bossuyt, Nathalie, additional, Vermeulen, Melissa, additional, Matheeussen, Veerle, additional, van Westreenen, Mireille, additional, Verkaik, Nelianne J, additional, Vogel, Marius, additional, van Rossum, Annemarie M C, additional, Afshar, Baharak, additional, Uldum, Søren Anker, additional, Emborg, Hanne-Dorthe, additional, Gullsby, Karolina, additional, Laine, Miia, additional, Peltola, Ville, additional, Heinonen, Santtu, additional, Døllner, Henrik, additional, Width, Frode Gran, additional, Christensen, Andreas, additional, Buonsenso, Danilo, additional, Rodrigues, Fernanda M P, additional, Rodrigues, Jorge, additional, Tsantila, Katerina, additional, Matsas, Minos, additional, Kalogera, Eleni, additional, Petridou, Evangelia, additional, Kopsidas, Ioannis, additional, Keše, Darja, additional, Nir-Paz, Ran, additional, Elinav, Hila, additional, Michael-Gayego, Ayelet, additional, Oishi, Tomohiro, additional, Saraya, Takeshi, additional, Hsieh, Yu-Chia, additional, Wu, Tsung Hua, additional, Maiwald, Matthias, additional, Loo, Liat Hui, additional, Sagar, Tanu, additional, Chaudhry, Rama, additional, Kociolek, Larry K, additional, Rodríguez, Nadia, additional, Lorenz, David, additional, and Blakiston, Matthew R, additional
Published: 2023
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10. Migrating a Well-Established Longitudinal Cohort Database From Oracle SQL to Research Electronic Data Entry (REDCap): Data Management Research and Design Study

Author: Kusejko, Katharina, Smith, Daniel, Scherrer, Alexandra, Paioni, Paolo, Kohns Vasconcelos, Malte, Aebi-Popp, Karoline, Kouyos, Roger D, Günthard, Huldrych F, and Kahlert, Christian R
Subjects: 610 Medicine & health
Abstract: BACKGROUND Providing user-friendly electronic data collection tools for large multicenter studies is key for obtaining high-quality research data. Research Electronic Data Capture (REDCap) is a software solution developed for setting up research databases with integrated graphical user interfaces for electronic data entry. The Swiss Mother and Child HIV Cohort Study (MoCHiV) is a longitudinal cohort study with around 2 million data entries dating back to the early 1980s. Until 2022, data collection in MoCHiV was paper-based. OBJECTIVE The objective of this study was to provide a user-friendly graphical interface for electronic data entry for physicians and study nurses reporting MoCHiV data. METHODS MoCHiV collects information on obstetric events among women living with HIV and children born to mothers living with HIV. Until 2022, MoCHiV data were stored in an Oracle SQL relational database. In this project, R and REDCap were used to develop an electronic data entry platform for MoCHiV with migration of already collected data. RESULTS The key steps for providing an electronic data entry option for MoCHiV were (1) design, (2) data cleaning and formatting, (3) migration and compliance, and (4) add-on features. In the first step, the database structure was defined in REDCap, including the specification of primary and foreign keys, definition of study variables, and the hierarchy of questions (termed "branching logic"). In the second step, data stored in Oracle were cleaned and formatted to adhere to the defined database structure. Systematic data checks ensured compliance to all branching logic and levels of categorical variables. REDCap-specific variables and numbering of repeated events for enabling a relational data structure in REDCap were generated using R. In the third step, data were imported to REDCap and then systematically compared to the original data. In the last step, add-on features, such as data access groups, redirections, and summary reports, were integrated to facilitate data entry in the multicenter MoCHiV study. CONCLUSIONS By combining different software tools-Oracle SQL, R, and REDCap-and building a systematic pipeline for data cleaning, formatting, and comparing, we were able to migrate a multicenter longitudinal cohort study from Oracle SQL to REDCap. REDCap offers a flexible way for developing customized study designs, even in the case of longitudinal studies with different study arms (ie, obstetric events, women, and mother-child pairs). However, REDCap does not offer built-in tools for preprocessing large data sets before data import. Additional software is needed (eg, R) for data formatting and cleaning to achieve the predefined REDCap data structure.
Published: 2023
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11. Detection of mostly viral pathogens and high proportion of antibiotic treatment initiation in hospitalised children with community-acquired pneumonia in Switzerland – baseline findings from the first two years of the KIDS-STEP trial

Author: Kohns Vasconcelos, Malte, Meyer Sauteur, Patrick M; https://orcid.org/0000-0002-4312-9803, Keitel, Kristina, Santoro, Regina, Egli, Adrian; https://orcid.org/0000-0002-3564-8603, Coslovsky, Michael; https://orcid.org/0000-0001-7678-7354, Seiler, Michelle; https://orcid.org/0000-0002-1263-5818, Lurà, Marco, Köhler, Henrik, Loevy, Natasha, Kahlert, Christian R; https://orcid.org/0000-0002-0784-3276, Heininger, Ulrich; https://orcid.org/0000-0001-8901-6778, Van den Anker, Johannes, Bielicki, Julia A; https://orcid.org/0000-0002-3902-5489, Kohns Vasconcelos, Malte, Meyer Sauteur, Patrick M; https://orcid.org/0000-0002-4312-9803, Keitel, Kristina, Santoro, Regina, Egli, Adrian; https://orcid.org/0000-0002-3564-8603, Coslovsky, Michael; https://orcid.org/0000-0001-7678-7354, Seiler, Michelle; https://orcid.org/0000-0002-1263-5818, Lurà, Marco, Köhler, Henrik, Loevy, Natasha, Kahlert, Christian R; https://orcid.org/0000-0002-0784-3276, Heininger, Ulrich; https://orcid.org/0000-0001-8901-6778, Van den Anker, Johannes, and Bielicki, Julia A; https://orcid.org/0000-0002-3902-5489
Abstract: AIMS OF THE STUDY: Globally, since the introduction of conjugate-vaccines against encapsulated bacteria, respiratory viruses have caused most hospitalisations for community-acquired pneumonia. The aim of this study was to describe pathogens detected and their association with clinical findings in Switzerland. METHODS: Baseline data were analysed for all trial participants enrolled between September 2018 and September 2020 into the KIDS-STEP Trial, a randomised controlled superiority trial on the effect of betamethasone on clinical stabilisation of children admitted with community-acquired pneumonia. Data included clinical presentation, antibiotic use and results of pathogen detection. In addition to routine sampling, nasopharyngeal specimens were analysed for respiratory pathogens using a panel polymerase chain reaction test covering 18 viral and 4 bacterial pathogens. RESULTS: 138 children with a median age of 3 years were enrolled at the eight trial sites. Fever (obligatory for enrolment) had been present for median 5 days before admission. Most common symptoms were reduced activity (129, 93.5%) and reduced oral intake (108, 78.3%). Oxygen saturation <92% was found in 43 (31.2%). Forty-three participants (29.0%) were already on antibiotic treatment prior to admission and 104 participants (75.4%) received antibiotic treatment on admission. Pathogen testing results were available from 132 children: 31 (23.5%) had respiratory syncytial virus detected, 21 (15.9%) human metapneumovirus. The pathogens detected showed expected seasonal and age preponderance and were not associated with chest X-ray findings. CONCLUSIONS: In the context of the predominantly viral pathogens detected, the majority of antibiotic treatment is probably unnecessary. The ongoing trial, as well as other studies, will be able to provide comparative pathogen detection data to compare pre- and post-COVID-19-pandemic settings.
Published: 2023

12. Migrating a Well-Established Longitudinal Cohort Database From Oracle SQL to Research Electronic Data Entry (REDCap): Data Management Research and Design Study

Author: Kusejko, Katharina; https://orcid.org/0000-0002-4638-1940, Smith, Daniel; https://orcid.org/0009-0002-8283-3227, Scherrer, Alexandra; https://orcid.org/0000-0003-4870-179X, Paioni, Paolo; https://orcid.org/0000-0002-3904-1606, Kohns Vasconcelos, Malte; https://orcid.org/0000-0002-6207-9442, Aebi-Popp, Karoline; https://orcid.org/0000-0002-9337-900X, Kouyos, Roger D; https://orcid.org/0000-0002-9220-8348, Günthard, Huldrych F; https://orcid.org/0000-0002-1142-6723, Kahlert, Christian R; https://orcid.org/0000-0002-0784-3276, Swiss HIV Cohort Study and the Swiss Mother and Child HIV Cohort, Kusejko, Katharina; https://orcid.org/0000-0002-4638-1940, Smith, Daniel; https://orcid.org/0009-0002-8283-3227, Scherrer, Alexandra; https://orcid.org/0000-0003-4870-179X, Paioni, Paolo; https://orcid.org/0000-0002-3904-1606, Kohns Vasconcelos, Malte; https://orcid.org/0000-0002-6207-9442, Aebi-Popp, Karoline; https://orcid.org/0000-0002-9337-900X, Kouyos, Roger D; https://orcid.org/0000-0002-9220-8348, Günthard, Huldrych F; https://orcid.org/0000-0002-1142-6723, Kahlert, Christian R; https://orcid.org/0000-0002-0784-3276, and Swiss HIV Cohort Study and the Swiss Mother and Child HIV Cohort
Abstract: BACKGROUND: Providing user-friendly electronic data collection tools for large multicenter studies is key for obtaining high-quality research data. Research Electronic Data Capture (REDCap) is a software solution developed for setting up research databases with integrated graphical user interfaces for electronic data entry. The Swiss Mother and Child HIV Cohort Study (MoCHiV) is a longitudinal cohort study with around 2 million data entries dating back to the early 1980s. Until 2022, data collection in MoCHiV was paper-based. OBJECTIVE: The objective of this study was to provide a user-friendly graphical interface for electronic data entry for physicians and study nurses reporting MoCHiV data. METHODS: MoCHiV collects information on obstetric events among women living with HIV and children born to mothers living with HIV. Until 2022, MoCHiV data were stored in an Oracle SQL relational database. In this project, R and REDCap were used to develop an electronic data entry platform for MoCHiV with migration of already collected data. RESULTS: The key steps for providing an electronic data entry option for MoCHiV were (1) design, (2) data cleaning and formatting, (3) migration and compliance, and (4) add-on features. In the first step, the database structure was defined in REDCap, including the specification of primary and foreign keys, definition of study variables, and the hierarchy of questions (termed "branching logic"). In the second step, data stored in Oracle were cleaned and formatted to adhere to the defined database structure. Systematic data checks ensured compliance to all branching logic and levels of categorical variables. REDCap-specific variables and numbering of repeated events for enabling a relational data structure in REDCap were generated using R. In the third step, data were imported to REDCap and then systematically compared to the original data. In the last step, add-on features, such as data access groups, redirections, and summary reports, were
Published: 2023

13. Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial

Author: Welzel, Tatjana, primary, Atkinson, Andrew, additional, Schöbi, Nina, additional, Andre, Maya C, additional, Bailey, Douggl G N, additional, Blanchard-Rohner, Geraldine, additional, Buettcher, Michael, additional, Grazioli, Serge, additional, Koehler, Henrik, additional, Perez, Marie-Helene, additional, Trück, Johannes, additional, Vanoni, Federica, additional, Zimmermann, Petra, additional, Sanchez, Carlos, additional, Bielicki, Julia A, additional, Schlapbach, Luregn J, additional, Bieri, Andreas, additional, Gysi, Spyridoula, additional, Janz, Indra, additional, Donner, Birgit, additional, Hammer, Jürg, additional, Heininger, Ulrich, additional, Kohns Vasconcelos, Malte, additional, Mettauer, Nicole, additional, Meyer, Alexandra, additional, Reppucci, Diana, additional, Schlaeppi, Chloé, additional, Trachsel, Daniel, additional, Vaezipour, Nina, additional, von Kalckreuth, Clemens, additional, Woerner, Andreas, additional, Zutter, Andreas, additional, Kottanattu, Lisa, additional, Mazzara, Calogero, additional, Severi Conti, Alessia, additional, Aebi, Christoph, additional, Agyeman, Philipp K A, additional, Duppenthaler, Andrea, additional, Glöckler, Martin, additional, Pallivathukal, Sabine, additional, Riedel, Thomas, additional, Cudré-Cung, Hong-Phuc, additional, Pavlovic, Mladen, additional, Bordessoule, Alice, additional, L'Huillier, Arnaud G, additional, Martin, Anne-Laure, additional, Polito, Angelo, additional, Rohr, Marie, additional, Rodriguez, Maria Isabel, additional, Wagner, Noemie, additional, Chanez, Vivianne, additional, Bressieux-Degueldre, Sabrina, additional, Ferry, Thomas, additional, Hofer, Michael, additional, Longchamp, David, additional, Natterer, Julia, additional, Oppenheim, Rebecca, additional, Donas, Alex, additional, Germann, Sara, additional, Hrup, Katja, additional, Kaiser, Daniela, additional, Kuen, Hans Peter, additional, Lütolf Erni, Michaela, additional, Schwendener Scholl, Katharina, additional, Stritt, Janine, additional, Wechselberger, Katharina, additional, Beck, Ingrid, additional, Birkenmaier, André, additional, Flade, Martin, additional, Rogdo, Bjarte, additional, Iglowstein, Ivo, additional, Lorenz, Philip, additional, Wachinger, Tanja, additional, Zöhrer, Konstanze, additional, Brotschi, Barbara, additional, Meyer Sauteur, Patrick M, additional, Pachlopnik Schmid, Jana, additional, Prader, Seraina, additional, Seiler, Michelle, additional, Weber, Kathrin, additional, Wütz, Daniela, additional, Whittaker, Elizabeth, additional, and Faust, Saul N, additional
Published: 2023
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14. Traitement antibiotique rationnel en pratique pédiatrique

Author: Bielicki, Julia Anna, primary and Kohns Vasconcelos, Malte, additional
Published: 2023
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15. Rationale Antibiotikatherapie in der pädiatrischen Praxis

Author: Bielicki, Julia Anna, primary and Kohns Vasconcelos, Malte, additional
Published: 2023
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16. Mycoplasma pneumoniae beyond the COVID-19 pandemic: where is it?

Author: Sauteur, Patrick M Meyer, primary, Chalker, Victoria J, additional, Berger, Christoph, additional, Nir-Paz, Ran, additional, Beeton, Michael L, additional, Pereyre, Sabine, additional, Bébéar, Cécile, additional, Wagner, Noémie, additional, Andreutti, Corinne, additional, Greub, Gilbert, additional, Agyeman, Philipp K A, additional, Aebi, Christoph, additional, Buettcher, Michael, additional, Kottanattu, Lisa, additional, Gaia, Valeria, additional, Imkamp, Frank, additional, Zbinden, Reinhard, additional, Sidorov, Semjon, additional, Niederer-Loher, Anita, additional, Barbey, Florence, additional, Egli, Adrian, additional, Heininger, Ulrich, additional, Schlaeppi, Chloé, additional, Papan, Cihan, additional, Kohns Vasconcelos, Malte, additional, Henrich, Birgit, additional, Mackenzie, Colin, additional, Dumke, Roger, additional, Schneider, Gerlinde, additional, Bossuyt, Nathalie, additional, Vermeulen, Melissa, additional, Loens, Katherine, additional, van Westreenen, Mireille, additional, Verkaik, Nelianne J, additional, van Rossum, Annemarie M C, additional, Day, Jessica, additional, Afshar, Baharak, additional, Peltola, Ville, additional, Heinonen, Santtu, additional, Renko, Marjo, additional, Tapiainen, Terhi, additional, Døllner, Henrik, additional, Rodrigues, Fernanda, additional, Matsas, Minos, additional, Kalogera, Eleni, additional, Petridou, Evangelia, additional, Kopsidas, Ioannis, additional, Zaoutis, Theoklis E, additional, Keše, Darja, additional, Elinav, Hila, additional, Michael-Gayego, Ayelet, additional, Namkoong, Ho, additional, Hsieh, Yu-Chia, additional, Maiwald, Matthias, additional, Loo, Liat Hui, additional, Chaudhry, Rama, additional, Kociolek, Larry K, additional, Rodríguez, Nadia, additional, Lorenz, David, additional, and Blakiston, Matthew, additional
Published: 2022
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17. A diagnostic algorithm for children presenting with peripheral facial nerve palsy and inconclusive diagnosis of neuroborreliosis.

Author: Mack, Ines, Kohns Vasconcelos, Malte, Ritz, Nicole, and Zimmermann, Petra
Subjects: *FACIAL paralysis, *LYME neuroborreliosis, *FACIAL nerve, *PERIPHERAL nervous system, *DIAGNOSIS, CENTRAL nervous system infections
Abstract: In children living in endemic areas, the presence of acute-onset PFP along with CSF pleocytosis characterised by over 90% lymphocytes has been found to have a high positive predictive value.[[3], [5]] Definitive diagnosis of neuroborreliosis, however, requires the detection of specific antibodies in CSF. Abbreviations CLIA Chemiluminescence immunoassay CMV Cytomegalovirus CNS Central nervous system CSF Cerebrospinal fluid CXCL13 C-X-C motiv chemokine ligand 13 EBV Epstein-Barr virus ED Emergency department ELISA Enzyme-linked immunosorbent assay Ig Immunoglobulin PCR Polymerase chain reaction PFP Peripheral facial nerve palsy WBC White blood count VZV Varicella-zoster virus INTRODUCTION In areas where pathogenic I Borrelia i spp. are endemic, over half of the children presenting with peripheral facial nerve palsy (PFP) are affected by neuroborreliosis.[[1]] In this setting, I Borrelia i spp. are the most frequent cause of paediatric PFP, surpassing idiopathic PFP (Bell's palsy).[[1]] Diagnosis of neuroborrelioses is based on cerebrospinal fluid (CSF) analysis. A second lumbar puncture will therefore have consequences on the diagnosis and treatment choice. [Extracted from the article]
Published: 2023
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18. Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity

Author: Marwali, Eva Miranda, primary, Kekalih, Aria, additional, Yuliarto, Saptadi, additional, Wati, Dyah Kanya, additional, Rayhan, Muhammad, additional, Valerie, Ivy Cerelia, additional, Cho, Hwa Jin, additional, Jassat, Waasila, additional, Blumberg, Lucille, additional, Masha, Maureen, additional, Semple, Calum, additional, Swann, Olivia V, additional, Kohns Vasconcelos, Malte, additional, Popielska, Jolanta, additional, Murthy, Srinivas, additional, Fowler, Robert A, additional, Guerguerian, Anne-Marie, additional, Streinu-Cercel, Anca, additional, Pathmanathan, Mohan Dass, additional, Rojek, Amanda, additional, Kartsonaki, Christiana, additional, Gonçalves, Bronner P, additional, Citarella, Barbara Wanjiru, additional, Merson, Laura, additional, Olliaro, Piero L, additional, and Dalton, Heidi Jean, additional
Published: 2022
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19. Prise en charge mdicale des rfugis mineurs d039Ukraine

Author: Jger, Fabienne N., primary, Berger, Christoph, additional, Buettcher, Michael, additional, Depallens, Sarah, additional, Heininger, Ulrich, additional, Heller, Yvon, additional, Kohns Vasconcelos, Malte, additional, Leforestier, Bodil, additional, Pellaud, Nicole, additional, Relly, Christa, additional, Trck, Johannes, additional, von Overbeck Ottino, Saskia, additional, Bernhard-Stirnemann, Sara, additional, Wagner, Nomie, additional, and Ritz, Nicole, additional
Published: 2022
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20. Junge Flchtlinge optimal versorgen

Author: Jger, Fabienne N., primary, Berger, Christoph, additional, Buettcher, Michael, additional, Depallens, Sarah, additional, Heininger, Ulrich, additional, Heller, Yvon, additional, Kohns Vasconcelos, Malte, additional, Leforestier, Bodil, additional, Pellaud, Nicole, additional, Relly, Christa, additional, Trck, Johannes, additional, von Overbeck Ottino, Saskia, additional, Bernhard-Stirnemann, Sara, additional, Wagner, Nomie, additional, and Ritz, Nicole, additional
Published: 2022
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21. Simultaneous presence of Mycoplasma salivarium and Tannerella forsythia in the implant sulcus after lateral augmentation with autogenous root grafts is associated with increased sulcus probing depth

Author: Groß, Karoline, primary, Sahin, Didem, additional, Kohns Vasconcelos, Malte, additional, Pfeffer, Klaus, additional, Schwarz, Frank, additional, and Henrich, Birgit, additional
Published: 2022
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22. Paediatric refugees from Ukraine: guidance for health care providers

Author: Jaeger, Fabienne N., primary, Berger, Christoph, additional, Buettcher, Michael, additional, Depallens, Sarah, additional, Heininger, Ulrich, additional, Heller, Yvon, additional, Kohns Vasconcelos, Malte, additional, Leforestier, Bodil, additional, Pellaud, Nicole, additional, Relly, Christa, additional, Trück, Johannes, additional, Von Overbeck Ottino, Saskia, additional, Wagner, Noémie, additional, and Ritz, Nicole, additional
Published: 2022
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23. Searching high and low: call for a joint ESPID-EUCAST survey on dosage of antibacterial agents in children–part one

Author: Aguilera-Alonso, David, Cantón, Rafael, Giske, Christian G., Kahlmeter, Gunnar, Kohns Vasconcelos, Malte, Papan, Cihan, and Turnidge, John
Published: 2022
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24. Children living with HIV in Europe:do migrants have worse treatment outcomes?

Author: Chappell, Elizabeth, Kohns Vasconcelos, Malte, Goodall, Ruth L., Galli, Luisa, Judd, A, Collins, IJ, Chappell, Elizabeth, Kohns Vasconcelos, Malte, Goodall, Ruth L., Galli, Luisa, Judd, A, and Collins, IJ
Abstract: Objectives: To assess the effect of migrant status on treatment outcomes among children living with HIV in Europe. Methods: Children aged < 18 years at the start of antiretroviral therapy (ART) in European paediatric HIV observational cohorts where ≥ 5% of children were migrants (defined as born abroad) were included. Three outcomes were considered: (i) severe immunosuppression-for-age; (ii) viraemic viral load (≥ 400 copies/mL) at 1 year after ART initiation; and (iii) AIDS/death after ART initiation. The effect of migrant status was assessed using univariable and multivariable logistic and Cox models. Results: Of 2620 children included across 12 European countries, 56% were migrants. At ART initiation, migrant children were older than domestic-born children (median 6.1 vs. 0.9 years, p < 0.001), with slightly higher proportions being severely immunocompromised (35% vs. 33%) and with active tuberculosis (2% vs. 1%), but a lower proportion with an AIDS diagnosis (14% vs. 19%) (all p < 0.001). At 1 year after beginning ART, a lower proportion of migrant children were viraemic (18% vs. 24%) but there was no difference in multivariable analysis (p = 0.702), and no difference in severe immunosuppression (p = 0.409). However, there was a trend towards higher risk of AIDS/death in migrant children (adjusted hazard ratio = 1.51, 95% confidence interval: 0.96–2.38, p = 0.072). Conclusions: After adjusting for characteristics at ART initiation, migrant children have virological and immunological outcomes at 1 year of ART that are comparable to those who are domestic-born, possibly indicating equity in access to healthcare in Europe. However, there was some evidence of a difference in AIDS-free survival, which warrants further monitoring.
Published: 2022

25. Paediatric refugees from Ukraine: guidance for health care providers

Author: Jaeger, Fabienne N; https://orcid.org/0000-0002-8441-3907, Berger, Christoph; https://orcid.org/0000-0002-2373-8804, Buettcher, Michael; https://orcid.org/0000-0001-6086-6162, Depallens, Sarah; https://orcid.org/0000-0002-7074-1985, Heininger, Ulrich; https://orcid.org/0000-0001-8901-6778, Heller, Yvon, Kohns Vasconcelos, Malte; https://orcid.org/0000-0002-6207-9442, Leforestier, Bodil, Pellaud, Nicole; https://orcid.org/0000-0001-8561-7146, Relly, Christa, Trück, Johannes; https://orcid.org/0000-0002-0418-7381, von Overbeck Ottino, Saskia; https://orcid.org/0000-0001-9235-7602, Wagner, Noémie; https://orcid.org/0000-0001-9133-9752, Ritz, Nicole; https://orcid.org/0000-0002-1498-1685, Jaeger, Fabienne N; https://orcid.org/0000-0002-8441-3907, Berger, Christoph; https://orcid.org/0000-0002-2373-8804, Buettcher, Michael; https://orcid.org/0000-0001-6086-6162, Depallens, Sarah; https://orcid.org/0000-0002-7074-1985, Heininger, Ulrich; https://orcid.org/0000-0001-8901-6778, Heller, Yvon, Kohns Vasconcelos, Malte; https://orcid.org/0000-0002-6207-9442, Leforestier, Bodil, Pellaud, Nicole; https://orcid.org/0000-0001-8561-7146, Relly, Christa, Trück, Johannes; https://orcid.org/0000-0002-0418-7381, von Overbeck Ottino, Saskia; https://orcid.org/0000-0001-9235-7602, Wagner, Noémie; https://orcid.org/0000-0001-9133-9752, and Ritz, Nicole; https://orcid.org/0000-0002-1498-1685
Abstract: BACKGROUND: With the invasion of Ukraine by the Russian Army in February 2022, refugees, the majority of whom are women and children, started fleeing the war to neighbouring countries. Even before the current escalation, the conflict in the eastern part of Ukraine has led to the internal displacement of more than 200,000 children, and many others have experienced attacks, e.g. on schools. This inevitably leads to limitations in health care delivery. During transit, overcrowding, poor shelter and vulnerability may further put refugees at increased risk for infectious diseases. This consensus document aims to provide information and guidance regarding health issues that paediatricians and general practitioners may face when caring for Ukrainian children. METHODS: Members of the Migrant Health Reference Group of Paediatrics Switzerland and the Paediatric Infectious Disease Group in Switzerland developed this recommendation between March and April 2022 in a modified Delphi process. RESULTS: A total of 50 recommendations were agreed on with a ≥80% consensus. These include the following topics: i) general aspects, including interpreter services, urgent health needs, personal history and general check-ups; ii) mental health, including how to search for signs of psychological distress without going into traumatic details; iii) vaccinations, including recommendations for evaluation and catch-up; iv) screening for tuberculosis, human immunodeficiency virus, and hepatitis B and C; and v) providing age-appropriate preventive and health service information. CONCLUSION: This document provides current evidence and guidance when caring for paediatric refugees from Ukraine. The recommendations focus on Switzerland but may well be used in other countries. These are based on current evidence and may need to be adapted to individual situations and once further evidence becomes available.
Published: 2022

26. Profiling of humoral immune responses to norovirus in children across Europe

Author: Villabruna, Nele, primary, Izquierdo Lara, Ray W, additional, Schapendonk, Claudia ME, additional, de Bruin, Erwin, additional, Chandler, Felicity, additional, Thao, Tran Thi Nhu, additional, Westerhuis, Brenda M, additional, van Beek, Janko, additional, Sigfrid, Louise, additional, Giaquinto, Carlo, additional, Goossens, Herman, additional, Bielicki, Julia A, additional, Kohns Vasconcelos, Malte, additional, Fraaij, Pieter LA, additional, Koopmans, Marion PG, additional, and de Graaf, Miranda, additional
Published: 2022
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27. Effect of amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with community-acquired pneumonia: The CAP-IT randomized clinical trial

Author: Bielicki, Julia A., Stöhr, Wolfgang, Barratt, Sam, Dunn, David, Naufal, Nishdha, Roland, Damian, Sturgeon, Kate, Finn, Adam, Rodriguez Ruiz, Juan Pablo, Malhotra, Surbhi, Powell, Colin, Faust, Saul N., Alcock, Anastasia E., Hall, Dani, Robinson, Gisela, Hawcutt, Daniel B., Lyttle, Mark D., Gibb, Diana M., Sharland, Mike, Molyneux, Elizabeth, Butler, Chris C., Smyth, Alan, Prichard, Catherine, Peto, Tim E.A., Cousens, Simon, Logan, Stuart, Bamford, Alasdair, Turkova, Anna, Goodman, Anna L., Fitzgerald, Felicity, Little, Paul S., Robotham, Julie, Wan, Mandy, Klein, Nigel, Rogers, Louise, Vitale, Elia, Rotheram, Matthew, Wright, Rachel, Lee, Elizabeth, Ohia, Udeme, Hartshorn, Stuart, Jyothish, Deepthi, Hopkins, Juliet, Ross, James G., Patel, Poonam, Fletcher, Hannah, Nundlall, Kribashnie, Carungcong, Jamie, Bull, Rhian, Burney, Nabila, Correia Da Costa, Patricia, Vergnano, Stefania, Walton, Beth, Smith, Alice, Ross, Michelle, Aplin, Lucie, Sheedy, Sarah, Kaur, Gurnie, Morgan, Jeff, Muller, Jennifer, Marshall, Gail, Nyamugunduru, Godfrey, Furness, John C., Eggington, Dawn, Holt, Susannah J., Gibbs, John, Burchett, Caroline, Lonsdale, Caroline, De-Beger, Sarah, Cheung, Ronny, Sheedy, Alyce B., Ahmad, Mohammad, Stockwell, Zoe, Giwa, Sarah, Murad, Arshid, Jerman, Katherine, Green, Joanna, Bird, Chris, Baron, Tanya K. Z., Segal, Shelley, Beer, Sally, Garcia Garcia, Maria Jose, Georgiou, Dom, Beadon, Kirsten, Martinez, Jose, Cantle, Fleur, Eastman, Hannah, Riozzi, Paul, Cotton, Hannah, Mullen, Niall, McCrone, Rhona, Corrigan, Paul, Salt, Gemma, Fairlie, Louise, Smith, Andrew, Starkey, Lizzie, Hayman, Mel, O'Riordan, Sean, Downes, Alice, Allen, Majorie, Turner, Louise, Ellis, Donna, Bandi, Srini, Patel, Rekha, Gough, Chris, McAulay, Megan, Conner, Louise, Gardner, Sharryn, Haslam, Zena, Morrison, Moira, Barrett, Michael J., Niermeyer, Madeleine, Barry, Ellen, Walton, Emily K., Kapur, Akshat, Richmond, Vivien, Foster, Steven J., Bland, R.M., Neil, Ashleigh, Milligan, Barry, Bannister, Helen, Bloom, Ben, Parikh, Ami, Skene, Imogen, Power, Helen, Boulton, Olivia, Astin-Chamberlain, Raine, Smith, David, Walters, Jonathon, Martin, Daniel, Noba, Lyrics, Potier, Katherine, Borland, Fiona, Wilson, Jill, Suleman, Zainab, Gilchrist, Judith, West, Noreen, Evans, Jayne, Morecombe, Juliet, Heath, Paul T., Iqbal, Yasser, Kohns Vasconcelos, Malte, Stefanova, Elena, Womack, Claire, Maconochie, Ian K., Laing, Suzanne, Jorgensen, Rikke, Nyirenda, Maggie, Keers, Sophie, Pilgrim, Samia, Gardiner, Emma, Cathie, Katrina, Bayreuther, Jane, Ensom, Ruth, Cornish, Emily K., Herrieven, Elizabeth-Jayne L., Townend, William, Sherris, Leanne, and Williams, Paul
Subjects: Male, medicine.medical_specialty, Randomization, Administration, Oral, Severity of Illness Index, Drug Administration Schedule, law.invention, Community-acquired pneumonia, Randomized controlled trial, law, Internal medicine, Severity of illness, medicine, Clinical endpoint, Humans, Duration of Therapy, business.industry, Pharmacology. Therapy, Hazard ratio, Respiratory infection, Amoxicillin, Infant, General Medicine, Pneumonia, medicine.disease, Patient Discharge, Anti-Bacterial Agents, Community-Acquired Infections, Child, Preschool, Retreatment, Female, Human medicine, business, medicine.drug
Abstract: This randomized clinical trial compares the need for re-treatment of respiratory infection following hospitalization for community-acquired pneumonia among children receiving amoxicillin at high doses vs low doses and at 3-days vs 7-days duration. Question For children with community-acquired pneumonia discharged from an emergency department, observational unit, or inpatient ward (within 48 hours), is subsequent outpatient treatment with oral amoxicillin at a dose of 35 to 50 mg/kg per day noninferior to 70 to 90 mg/kg per day, and is a 3-day course noninferior to 7 days, with regard to the need for antibiotic re-treatment? Findings In this 2 x 2 factorial randomized clinical trial of 814 children requiring amoxicillin for community-acquired pneumonia at hospital discharge, antibiotic re-treatment within 28 days occurred in 12.6% vs 12.4% of those randomized to lower vs higher doses, and in 12.5% vs 12.5% of those randomized to 3-day vs 7-day amoxicillin duration. Both comparisons met the prespecified 8% noninferiority margin. Meaning Among children with community-acquired pneumonia discharged from an emergency department, observational unit, or inpatient ward, further outpatient treatment with oral amoxicillin at a dose of 35 to 50 mg/kg per day was noninferior to a dose of 70 to 90 mg/kg per day and 3 days was noninferior to 7 days with regard to the need for later antibiotic re-treatment. Importance The optimal dose and duration of oral amoxicillin for children with community-acquired pneumonia (CAP) are unclear. Objective To determine whether lower-dose amoxicillin is noninferior to higher dose and whether 3-day treatment is noninferior to 7 days. Design, Setting, and Participants Multicenter, randomized, 2 x 2 factorial noninferiority trial enrolling 824 children, aged 6 months and older, with clinically diagnosed CAP, treated with amoxicillin on discharge from emergency departments and inpatient wards of 28 hospitals in the UK and 1 in Ireland between February 2017 and April 2019, with last trial visit on May 21, 2019. Interventions Children were randomized 1:1 to receive oral amoxicillin at a lower dose (35-50 mg/kg/d; n = 410) or higher dose (70-90 mg/kg/d; n = 404), for a shorter duration (3 days; n = 413) or a longer duration (7 days; n = 401). Main Outcomes and Measures The primary outcome was clinically indicated antibiotic re-treatment for respiratory infection within 28 days after randomization. The noninferiority margin was 8%. Secondary outcomes included severity/duration of 9 parent-reported CAP symptoms, 3 antibiotic-related adverse events, and phenotypic resistance in colonizing Streptococcus pneumoniae isolates. Results Of 824 participants randomized into 1 of the 4 groups, 814 received at least 1 dose of trial medication (median [IQR] age, 2.5 years [1.6-2.7]; 421 [52%] males and 393 [48%] females), and the primary outcome was available for 789 (97%). For lower vs higher dose, the primary outcome occurred in 12.6% with lower dose vs 12.4% with higher dose (difference, 0.2% [1-sided 95% CI -infinity to 4.0%]), and in 12.5% with 3-day treatment vs 12.5% with 7-day treatment (difference, 0.1% [1-sided 95% CI -infinity to 3.9]). Both groups demonstrated noninferiority with no significant interaction between dose and duration (P = .63). Of the 14 prespecified secondary end points, the only significant differences were 3-day vs 7-day treatment for cough duration (median 12 days vs 10 days; hazard ratio [HR], 1.2 [95% CI, 1.0 to 1.4]; P = .04) and sleep disturbed by cough (median, 4 days vs 4 days; HR, 1.2 [95% CI, 1.0 to 1.4]; P = .03). Among the subgroup of children with severe CAP, the primary end point occurred in 17.3% of lower-dose recipients vs 13.5% of higher-dose recipients (difference, 3.8% [1-sided 95% CI, -infinity to10%]; P value for interaction = .18) and in 16.0% with 3-day treatment vs 14.8% with 7-day treatment (difference, 1.2% [1-sided 95% CI, -infinity to 7.4%]; P value for interaction = .73). Conclusions and Relevance Among children with CAP discharged from an emergency department or hospital ward (within 48 hours), lower-dose outpatient oral amoxicillin was noninferior to higher dose, and 3-day duration was noninferior to 7 days, with regard to need for antibiotic re-treatment. However, disease severity, treatment setting, prior antibiotics received, and acceptability of the noninferiority margin require consideration when interpreting the findings.
Published: 2021
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28. Detection of invasive Trichosporon asahii in patient blood by a fungal PCR array

Author: Weber, Jasmin K., primary, Scharf, Sebastian, additional, Walther, Grit, additional, Flüh, Greta, additional, MacKenzie, Colin R., additional, Kondakci, Mustafa, additional, Henrich, Birgit, additional, and Kohns Vasconcelos, Malte, additional
Published: 2021
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29. The value of open-source clinical science in pandemic response: lessons from ISARIC

Author: Abbas, Ali, primary, Abdukahil, Sheryl Ann, additional, Abdulkadir, Nurul Najmee, additional, Abe, Ryuzo, additional, Abel, Laurent, additional, Absil, Lara, additional, Acharya, Subhash, additional, Acker, Andrew, additional, Adachi, Shingo, additional, Adam, Elisabeth, additional, Adrião, Diana, additional, Ageel, Saleh Al, additional, Ahmed, Shakeel, additional, Ain, Quratul, additional, Ainscough, Kate, additional, Aisa, Tharwat, additional, Ait Hssain, Ali, additional, Ait Tamlihat, Younes, additional, Akimoto, Takako, additional, Akmal, Ernita, additional, Al Qasim, Eman, additional, Alalqam, Razi, additional, Alam, Tanvir, additional, Al-dabbous, Tala, additional, Alegesan, Senthilkumar, additional, Alegre, Cynthia, additional, Alessi, Marta, additional, Alex, Beatrice, additional, Alexandre, Kévin, additional, Al-Fares, Abdulrahman, additional, Alfoudri, Huda, additional, Ali, Imran, additional, Ali Shah, Naseem, additional, Alidjnou, Kazali Enagnon, additional, Aliudin, Jeffrey, additional, Alkhafajee, Qabas, additional, Allavena, Clotilde, additional, Allou, Nathalie, additional, Altaf, Aneela, additional, Alves, João, additional, Alves, João Melo, additional, Alves, Rita, additional, Amaral, Maria, additional, Amira, Nur, additional, Ammerlaan, Heidi, additional, Ampaw, Phoebe, additional, Andini, Roberto, additional, Andrejak, Claire, additional, Angheben, Andrea, additional, Angoulvant, François, additional, Ansart, Séverine, additional, Anthonidass, Sivanesen, additional, Antonelli, Massimo, additional, Antunes de Brito, Carlos Alexandre, additional, Anwar, Kazi Rubayet, additional, Apriyana, Ardiyan, additional, Arabi, Yaseen, additional, Aragao, Irene, additional, Arali, Rajeshwari, additional, Arancibia, Francisco, additional, Araujo, Carolline, additional, Arcadipane, Antonio, additional, Archambault, Patrick, additional, Arenz, Lukas, additional, Arlet, Jean-Benoît, additional, Arnold-Day, Christel, additional, Aroca, Ana, additional, Arora, Lovkesh, additional, Arora, Rakesh, additional, Artaud-Macari, Elise, additional, Aryal, Diptesh, additional, Asaki, Motohiro, additional, Asensio, Angel, additional, Ashley, Elizabeth, additional, Ashraf, Muhammad, additional, Ashraf, Sheharyar, additional, Asim, Mohammad, additional, Assie, Jean Baptiste, additional, Asyraf, Amirul, additional, Atique, Anika, additional, Attanyake, AM Udara Lakshan, additional, Auchabie, Johann, additional, Aumaitre, Hugues, additional, Auvet, Adrien, additional, Azemar, Laurène, additional, Azoulay, Cecile, additional, Bach, Benjamin, additional, Bachelet, Delphine, additional, Badr, Claudine, additional, Baig, Nadia, additional, Baillie, J. Kenneth, additional, Baird, J Kevin, additional, Bak, Erica, additional, Bakakos, Agamemnon, additional, Bakar, Nazreen Abu, additional, Bal, Andriy, additional, Balakrishnan, Mohanaprasanth, additional, Balan, Valeria, additional, Bani-Sadr, Firouzé, additional, Barbalho, Renata, additional, Barbosa, Nicholas Yuri, additional, Barclay, Wendy S., additional, Barnett, Saef Umar, additional, Barnikel, Michaela, additional, Barrasa, Helena, additional, Barrelet, Audrey, additional, Barrigoto, Cleide, additional, Bartoli, Marie, additional, Bartone, Cheryl, additional, Baruch, Joaquín, additional, Bashir, Mustehan, additional, Basmaci, Romain, additional, Basri, Muhammad Fadhli Hassin, additional, Bastos, Diego, additional, Battaglini, Denise, additional, Bauer, Jules, additional, Bautista Rincon, Diego Fernando, additional, Bazan Dow, Denisse, additional, Bedossa, Alexandra, additional, Bee, Ker Hong, additional, Behilill, Sylvie, additional, Beishuizen, Albertus, additional, Beljantsev, Aleksandr, additional, Bellemare, David, additional, Beltrame, Anna, additional, Beltrão, Beatriz Amorim, additional, Beluze, Marine, additional, Benech, Nicolas, additional, Benjiman, Lionel Eric, additional, Benkerrou, Dehbia, additional, Bennett, Suzanne, additional, Bento, Luís, additional, Berdal, Jan-Erik, additional, Bergeaud, Delphine, additional, Bergin, Hazel, additional, Bernal Sobrino, José Luis, additional, Bertoli, Giulia, additional, Bertolino, Lorenzo, additional, Bessis, Simon, additional, Betz, Adam, additional, Bevilcaqua, Sybille, additional, Bezulier, Karine, additional, Bhatt, Amar, additional, Bhavsar, Krishna, additional, Bianchi, Isabella, additional, Bianco, Claudia, additional, Bidin, Farah Nadiah, additional, Bikram Singh, Moirangthem, additional, Bin Humaid, Felwa, additional, Bin Kamarudin, Mohd Nazlin, additional, Bissuel, François, additional, Biston, Patrick, additional, Bitker, Laurent, additional, Blanco-Schweizer, Pablo, additional, Blier, Catherine, additional, Bloos, Frank, additional, Blot, Mathieu, additional, Blumberg, Lucille, additional, Boccia, Filomena, additional, Bodenes, Laetitia, additional, Bogaarts, Alice, additional, Bogaert, Debby, additional, Boivin, Anne-Hélène, additional, Bolze, Pierre-Adrien, additional, Bompart, François, additional, Bonfasius, Aurelius, additional, Borges, Diogo, additional, Borie, Raphaël, additional, Bosse, Hans Martin, additional, Botelho-Nevers, Elisabeth, additional, Bouadma, Lila, additional, Bouchaud, Olivier, additional, Bouchez, Sabelline, additional, Bouhmani, Dounia, additional, Bouhour, Damien, additional, Bouiller, Kévin, additional, Bouillet, Laurence, additional, Bouisse, Camile, additional, Boureau, Anne-Sophie, additional, Bourke, John, additional, Bouscambert, Maude, additional, Bousquet, Aurore, additional, Bouziotis, Jason, additional, Boxma, Bianca, additional, Boyer-Besseyre, Marielle, additional, Boylan, Maria, additional, Bozza, Fernando Augusto, additional, Brack, Matthew, additional, Braconnier, Axelle, additional, Braga, Cynthia, additional, Brandenburger, Timo, additional, Brás Monteiro, Filipa, additional, Brazzi, Luca, additional, Breen, Dorothy, additional, Breen, Patrick, additional, Brett, Stephen, additional, Brickell, Kathy, additional, Broadley, Tessa, additional, Browne, Alex, additional, Browne, Shaunagh, additional, Brozzi, Nicolas, additional, Brusse-Keizer, Marjolein, additional, Buchtele, Nina, additional, Buesaquillo, Christian, additional, Bugaeva, Polina, additional, Buisson, Marielle, additional, Burhan, Erlina, additional, Burrell, Aidan, additional, Bustos, Ingrid G., additional, Butnaru, Denis, additional, Cabie, André, additional, Cabral, Susana, additional, Caceres, Eder, additional, Cadoz, Cyril, additional, Callahan, Mia, additional, Calligy, Kate, additional, Calvache, Jose Andres, additional, Cam, João, additional, Campana, Valentine, additional, Campbell, Paul, additional, Campisi, Josie, additional, Canepa, Cecilia, additional, Cantero, Mireia, additional, Caraux-Paz, Pauline, additional, Cárcel, Sheila, additional, Cardellino, Chiara Simona, additional, Cardoso, Filipa, additional, Cardoso, Filipe, additional, Cardoso, Nelson, additional, Cardoso, Sofia, additional, Carelli, Simone, additional, Carlier, Nicolas, additional, Carmoi, Thierry, additional, Carney, Gayle, additional, Carpenter, Chloe, additional, Carqueja, Inês, additional, Carret, Marie-Christine, additional, Carrier, François Martin, additional, Carroll, Ida, additional, Carson, Gail, additional, Carton, Ed, additional, Casanova, Maire-Laure, additional, Cascão, Mariana, additional, Casey, Siobhan, additional, Casimiro, José, additional, Cassandra, Bailey, additional, Castañeda, Silvia, additional, Castanheira, Nidyanara, additional, Castor-Alexandre, Guylaine, additional, Castrillón, Henry, additional, Castro, Ivo, additional, Catarino, Ana, additional, Catherine, François-Xavier, additional, Cattaneo, Paolo, additional, Cavalin, Roberta, additional, Cavalli, Giulio Giovanni, additional, Cavayas, Alexandros, additional, Ceccato, Adrian, additional, Cervantes-Gonzalez, Minerva, additional, Chair, Anissa, additional, Chakveatze, Catherine, additional, Chan, Adrienne, additional, Chand, Meera, additional, Chantalat Auger, Christelle, additional, Chapplain, Jean-Marc, additional, Chas, Julie, additional, Chaudary, Mobin, additional, Chávez Iñiguez, Jonathan Samuel, additional, Chen, Anjellica, additional, Chen, Yih-Sharng, additional, Cheng, Matthew Pellan, additional, Cheret, Antoine, additional, Chiarabini, Thibault, additional, Chica, Julian, additional, Chidambaram, Suresh Kumar, additional, Chin-Tho, Leong, additional, Chirouze, Catherine, additional, Chiumello, Davide, additional, Cho, Hwa Jin, additional, Cho, Sung-Min, additional, Cholley, Bernard, additional, Chopin, Marie-Charlotte, additional, Chow, Ting Soo, additional, Chow, Yock Ping, additional, Chua, Hiu Jian, additional, Chua, Jonathan, additional, Cidade, Jose Pedro, additional, Cisneros Herreros, José Miguel, additional, Citarella, Barbara Wanjiru, additional, Ciullo, Anna, additional, Clarke, Emma, additional, Clarke, Jennifer, additional, Claure Del Granado, Rolando, additional, Clohisey, Sara, additional, Cobb, J. Perren, additional, Coca, Necsoi, additional, Codan, Cassidy, additional, Cody, Caitriona, additional, Coelho, Alexandra, additional, Coles, Megan, additional, Colin, Gwenhaël, additional, Collins, Michael, additional, Colombo, Sebastiano Maria, additional, Combs, Pamela, additional, Connolly, Jennifer, additional, Connor, Marie, additional, Conrad, Anne, additional, Contreras, Sofía, additional, Conway, Elaine, additional, Cooke, Graham S., additional, Copland, Mary, additional, Cordel, Hugues, additional, Corley, Amanda, additional, Cormican, Sarah, additional, Cornelis, Sabine, additional, Cornet, Alexander Daniel, additional, Corpuz, Arianne Joy, additional, Cortegiani, Andrea, additional, Corvaisier, Grégory, additional, Costigan, Emma, additional, Couffignal, Camille, additional, Couffin-Cadiergues, Sandrine, additional, Courtois, Roxane, additional, Cousse, Stéphanie, additional, Cregan, Rachel, additional, Crepy D'Orleans, Charles, additional, Croonen, Sabine, additional, Crowl, Gloria, additional, Crump, Jonathan, additional, Cruz, Claudina, additional, Cruz Berm, Juan Luis, additional, Cruz Rojo, Jaime, additional, Csete, Marc, additional, Cucino, Alberto, additional, Cullen, Ailbhe, additional, Cullen, Caroline, additional, Cummings, Matthew, additional, Curley, Gerard, additional, Curlier, Elodie, additional, Curran, Colleen, additional, Custodio, Paula, additional, da Silva Filipe, Ana, additional, Da Silveira, Charlene, additional, Dabaliz, Al-Awwab, additional, Dagens, Andrew, additional, Dahly, Darren, additional, Dalton, Heidi, additional, Dalton, Jo, additional, Daly, Seamus, additional, D'Amico, Federico, additional, Daneman, Nick, additional, Daniel, Corinne, additional, Dankwa, Emmanuelle A, additional, Dantas, Jorge, additional, D’Aragon, Frédérick, additional, de Boer, Mark, additional, de Loughry, Gillian, additional, de Mendoza, Diego, additional, De Montmollin, Etienne, additional, de Oliveira França, Rafael Freitas, additional, de Pinho Oliveira, Ana Isabel, additional, De Rosa, Rosanna, additional, de Silva, Thushan, additional, de Vries, Peter, additional, Deacon, Jillian, additional, Dean, David, additional, Debard, Alexa, additional, DeBenedictis, Bianca, additional, Debray, Marie-Pierre, additional, DeCastro, Nathalie, additional, Dechert, William, additional, Deconninck, Lauren, additional, Decours, Romain, additional, Defous, Eve, additional, Delacroix, Isabelle, additional, Delaveuve, Eric, additional, Delavigne, Karen, additional, Delfos, Nathalie M., additional, Deligiannis, Ionna, additional, Dell'Amore, Andrea, additional, Delmas, Christelle, additional, Delobel, Pierre, additional, Delsing, Corine, additional, Demonchy, Elisa, additional, Denis, Emmanuelle, additional, Deplanque, Dominique, additional, Depuydt, Pieter, additional, Desai, Mehul, additional, Descamps, Diane, additional, Desvallée, Mathilde, additional, Dewayanti, Santi, additional, Diallo, Alpha, additional, Diamantis, Sylvain, additional, Dias, André, additional, Diaz, Priscila, additional, Diaz, Rodrigo, additional, Diaz Diaz, Juan Jose, additional, Didier, Kévin, additional, Diehl, Jean-Luc, additional, Dieperink, Wim, additional, Dimet, Jérôme, additional, Dinot, Vincent, additional, Diop, Fara, additional, Diouf, Alphonsine, additional, Dishon, Yael, additional, Dixit, Devika, additional, Djossou, Félix, additional, Docherty, Annemarie B., additional, Doherty, Helen, additional, Dondorp, Arjen M, additional, Dong, Andy, additional, Donnelly, Christl A., additional, Donnelly, Maria, additional, Donohue, Chloe, additional, Donohue, Sean, additional, Donohue, Yoann, additional, Doran, Ciara, additional, Doran, Peter, additional, Dorival, Céline, additional, D'Ortenzio, Eric, additional, Douglas, James Joshua, additional, Douma, Renee, additional, Dournon, Nathalie, additional, Downer, Triona, additional, Downey, Joanne, additional, Downing, Mark, additional, Drake, Tom, additional, Driscoll, Aoife, additional, Dryden, Murray, additional, Duarte Fonseca, Claudio, additional, Dubee, Vincent, additional, Dubos, François, additional, Ducancelle, Alexandre, additional, Duculan, Toni, additional, Dudman, Susanne, additional, Duggal, Abhijit, additional, Dunand, Paul, additional, Dunning, Jake, additional, Duplaix, Mathilde, additional, Durante-Mangoni, Emanuele, additional, Durham III, Lucian, additional, Dussol, Bertrand, additional, Duthoit, Juliette, additional, Duval, Xavier, additional, Dyrhol-Riise, Anne Margarita, additional, Ean, Sim Choon, additional, Echeverria-Villalobos, Marco, additional, Egan, Siobhan, additional, Eira, Carla, additional, El Sanharawi, Mohammed, additional, Elapavaluru, Subbarao, additional, Elharrar, Brigitte, additional, Ellerbroek, Jacobien, additional, Eloy, Philippine, additional, Elshazly, Tarek, additional, Elyazar, Iqbal, additional, Enderle, Isabelle, additional, Endo, Tomoyuki, additional, Eng, Chan Chee, additional, Engelmann, Ilka, additional, Enouf, Vincent, additional, Epaulard, Olivier, additional, Escher, Martina, additional, Esperatti, Mariano, additional, Esperou, Hélène, additional, Esposito-Farese, Marina, additional, Estevão, João, additional, Etienne, Manuel, additional, Ettalhaoui, Nadia, additional, Everding, Anna Greti, additional, Evers, Mirjam, additional, Fabre, Isabelle, additional, Fabre, Marc, additional, Faheem, Amna, additional, Fahy, Arabella, additional, Fairfield, Cameron J., additional, Fakar, Zul, additional, Faria, Pedro, additional, Farooq, Ahmed, additional, Farrar, Jeremy J., additional, Farshait, Nataly, additional, Fateena, Hanan, additional, Fatoni, Arie Zainul, additional, Faure, Karine, additional, Favory, Raphaël, additional, Fayed, Mohamed, additional, Feely, Niamh, additional, Feeney, Laura, additional, Fernandes, Jorge, additional, Fernandes, Marília, additional, Fernandes, Susana, additional, Ferrand, François-Xavier, additional, Ferrand Devouge, Eglantine, additional, Ferrão, Joana, additional, Ferraz, Mário, additional, Ferreira, Benigno, additional, Ferreira, Sílvia, additional, Ferrer-Roca, Ricard, additional, Ferriere, Nicolas, additional, Ficko, Céline, additional, Figueiredo-Mello, Claudia, additional, Fiorda, Juan, additional, Flament, Thomas, additional, Flateau, Clara, additional, Fletcher, Tom, additional, Florio, Letizia Lucia, additional, Flynn, Brigid, additional, Flynn, Deirdre, additional, Foley, Claire, additional, Foley, Jean, additional, Fomin, Victor, additional, Fonseca, Tatiana, additional, Fontela, Patricia, additional, Forsyth, Simon, additional, Foster, Denise, additional, Foti, Giuseppe, additional, Fourn, Erwan, additional, Fowler, Robert A., additional, Fraher, Dr Marianne, additional, Franch-Llasat, Diego, additional, Fraser, Christophe, additional, Fraser, John F., additional, Freire, Marcela Vieira, additional, Freitas Ribeiro, Ana, additional, Friedrich, Caren, additional, Fritz, Ricardo, additional, Fry, Stéphanie, additional, Fuentes, Nora, additional, Fukuda, Masahiro, additional, Gaborieau, Valérie, additional, Gaci, Rostane, additional, Gagliardi, Massimo, additional, Gagnard, Jean-Charles, additional, Gagné, Nathalie, additional, Gagneux-Brunon, Amandine, additional, Gaião, Sérgio, additional, Gail Skeie, Linda, additional, Gallagher, Phil, additional, Gallego Curto, Elena, additional, Gamble, Carrol, additional, Gani, Yasmin, additional, Garan, Arthur, additional, Garcia, Rebekha, additional, García Barrio, Noelia, additional, Garcia-Diaz, Julia, additional, Garcia-Gallo, Esteban, additional, Garimella, Navya, additional, Garot, Denis, additional, Garrait, Valérie, additional, Gauli, Basanta, additional, Gault, Nathalie, additional, Gavin, Aisling, additional, Gavrylov, Anatoliy, additional, Gaymard, Alexandre, additional, Gebauer, Johannes, additional, Geraud, Eva, additional, Gerbaud Morlaes, Louis, additional, Germano, Nuno, additional, ghisulal, praveen kumar, additional, Ghosn, Jade, additional, Giani, Marco, additional, Giaquinto, Carlo, additional, Gibson, Jess, additional, Gigante, Tristan, additional, Gilg, Morgane, additional, Gilroy, Elaine, additional, Giordano, Guillermo, additional, Girvan, Michelle, additional, Gissot, Valérie, additional, Gitahi, Judy, additional, Giwangkancana, Gezy, additional, Glikman, Daniel, additional, Glybochko, Petr, additional, Gnall, Eric, additional, Goco, Geraldine, additional, Goehringer, François, additional, Goepel, Siri, additional, Goffard, Jean-Christophe, additional, Goh, Jin Yi, additional, Golob, Jonathan, additional, Gomes, Rui, additional, Gomez, Kyle, additional, Gómez-Junyent, Joan, additional, Gominet, Marie, additional, Gonzalez, Alicia, additional, Gordon, Patricia, additional, Gordon, Anthony, additional, Gorenne, Isabelle, additional, Goubert, Laure, additional, Goujard, Cécile, additional, Goulenok, Tiphaine, additional, Grable, Margarite, additional, Graf, Jeronimo, additional, Grandin, Edward Wilson, additional, Granier, Pascal, additional, Grasselli, Giacomo, additional, Grazioli, Lorenzo, additional, Green, Christopher A., additional, Greene, Courtney, additional, Greenhalf, William, additional, Greffe, Segolène, additional, Grieco, Domenico Luca, additional, Griffee, Matthew, additional, Griffiths, Fiona, additional, Grigoras, Ioana, additional, Groenendijk, Albert, additional, Grosse Lordemann, Anja, additional, Gruner, Heidi, additional, Gu, Yusing, additional, Guarracino, Fabio, additional, Guedj, Jérémie, additional, Guego, Martin, additional, Guellec, Dewi, additional, Guerguerian, Anne-Marie, additional, Guerreiro, Daniela, additional, Guery, Romain, additional, Guillaumot, Anne, additional, Guilleminault, Laurent, additional, Guimarães de Castro, Maisa, additional, Guimard, Thomas, additional, Haalboom, Marieke, additional, Haber, Daniel, additional, Habraken, Hannah, additional, Hachemi, Ali, additional, Hadri, Nadir, additional, Haidash, Olena, additional, Haider, Saeeda, additional, Haidri, Fakhir, additional, Hakak, Sheeba, additional, Hall, Adam, additional, Hall, Matthew, additional, Halpin, Sophie, additional, Hamer, Ansley, additional, Hamers, Raph, additional, Hamidfar, Rebecca, additional, Hammond, Terese, additional, Han, Lim Yuen, additional, Haniffa, Rashan, additional, Hao, Kok Wei, additional, Hardwick, Hayley, additional, Harrison, Ewen M., additional, Harrison, Janet, additional, Harrison, Samuel Bernard Ekow, additional, Hartman, Alan, additional, Hashmi, Junaid, additional, Hashmi, Madiha, additional, Hayat, Muhammad, additional, Hayes, Ailbhe, additional, Hays, Leanne, additional, Heerman, Jan, additional, Heggelund, Lars, additional, Hendry, Ross, additional, Hennessy, Martina, additional, Henriquez, Aquiles, additional, Hentzien, Maxime, additional, Herekar, Fivzia, additional, Hernandez-Montfort, Jaime, additional, Herr, Daniel, additional, Hershey, Andrew, additional, Hesstvedt, Liv, additional, Hidayah, Astarini, additional, Higgins, Dawn, additional, Higgins, Eibhilin, additional, HigginsOKeeffe, Grainne, additional, Hinchion, Rita, additional, Hinton, Samuel, additional, Hiraiwa, Hiroaki, additional, Hitoto, Hikombo, additional, Ho, Antonia, additional, Ho, Yi Bin, additional, Hoctin, Alexandre, additional, Hoffmann, Isabelle, additional, Hoh, Wei Han, additional, Hoiting, Oscar, additional, Holt, Rebecca, additional, Holter, Jan Cato, additional, Horby, Peter, additional, Horcajada, Juan Pablo, additional, Hoshino, Koji, additional, Hoshino, Kota, additional, Houas, Ikram, additional, Hough, Catherine L., additional, Houltham, Stuart, additional, Hsu, Jimmy Ming-Yang, additional, Hulot, Jean-Sébastien, additional, Hussain, Iqbal, additional, Ijaz, Samreen, additional, Illes, Hajnal-Gabriela, additional, Imbert, Patrick, additional, Imran, Mohammad, additional, Imran Sikander, Rana, additional, Inácio, Hugo, additional, Infante Dominguez, Carmen, additional, Ing, Yun Sii, additional, Iosifidis, Elias, additional, Ippolito, Mariachiara, additional, Isgett, Sarah, additional, Ishani, Palliya Guruge Pramodya Ishani, additional, Isidoro, Tiago, additional, Ismail, Nadiah, additional, Isnard, Margaux, additional, Itai, Junji, additional, Ito, Asami, additional, Ivulich, Daniel, additional, Jaafar, Danielle, additional, Jaafoura, Salma, additional, Jabot, Julien, additional, Jackson, Clare, additional, Jamieson, Nina, additional, Jaquet, Pierre, additional, Jassat, Waasila, additional, Jaud-Fischer, Coline, additional, Jaureguiberry, Stéphane, additional, Javidfar, Jeffrey, additional, Jawad, Issrah, additional, Jaworsky, Denise, additional, Jayakumar, Devachandran, additional, Jego, Florence, additional, Jelani, Anilawati Mat, additional, Jenum, Synne, additional, Jimbo-Sotomayor, Ruth, additional, Job, van der Palen, additional, Joe, Ong Yiaw, additional, Jorge García, Ruth N., additional, Joseph, Cédric, additional, Joseph, Mark, additional, Joshi, Swosti, additional, Jourdain, Mercé, additional, Jouvet, Philippe, additional, June, Jennifer, additional, Jung, Anna, additional, Jung, Hanna, additional, Juzar, Dafsah, additional, Kafif, Ouifiya, additional, Kaguelidou, Florentia, additional, Kaisbain, Neerusha, additional, Kaleesvran, Thavamany, additional, Kali, Sabina, additional, Kalicinska, Alina, additional, Kalomoiri, Smaragdi, additional, Kamal, Saima, additional, Kamaluddin, Muhammad Aisar Ayadi, additional, Kamaruddin, Zul Amali Che, additional, Kamarudin, Nadiah, additional, Kandamby, Darshana Hewa, additional, Kandel, Chris, additional, Kang, Kong Yeow, additional, Kant, Ravi, additional, Kanwal, Darakhshan, additional, Kanyawati, Dyah, additional, Karki, Bipin, additional, Karpayah, Pratap, additional, Karsies, Todd, additional, Kartsonaki, Christiana, additional, Kasugai, Daisuke, additional, Kataria, Anant, additional, Katz, Kevin, additional, Kaur, Aasmine, additional, Kaur Johal, Simreen, additional, Kawasaki, Tatsuya, additional, Kay, Christy, additional, Keane, Hannah, additional, Keating, Seán, additional, Kellam, Paul, additional, Kelly, Andrea, additional, Kelly, Aoife, additional, Kelly, Claire, additional, Kelly, Niamh, additional, Kelly, Sadie, additional, Kelly, Yvelynne, additional, Kelsey, Maeve, additional, Kennedy, Ryan, additional, Kennon, Kalynn, additional, Kernan, Maeve, additional, Kerroumi, Younes, additional, Keshav, Sharma, additional, Kestelyn, Evelyne, additional, Khalid, Imrana, additional, Khalid, Osama, additional, Khalil, Antoine, additional, Khan, Coralie, additional, Khan, Irfan, additional, Khanal, Sushil, additional, Kho, Michelle E, additional, Khoo, Denisa, additional, Khoo, Ryan, additional, Khoo, Saye, additional, Khoso, Nasir, additional, Kiat, Khor How, additional, Kida, Yuri, additional, Kiiza, Peter, additional, Kildal, Anders Benjamin, additional, Kim, Jae Burm, additional, Kimmoun, Antoine, additional, Kindgen-Milles, Detlef, additional, King, Alexander, additional, Kitamura, Nobuya, additional, Klenerman, Paul, additional, Klont, Rob, additional, Kloumann Bekken, Gry, additional, Knight, Stephen, additional, Kobbe, Robin, additional, Kodippily, Chamira, additional, Kohns Vasconcelos, Malte, additional, Koirala, Sabin, additional, Komatsu, Mamoru, additional, Korten, Volkan, additional, Kosgei, Caroline, additional, Kpangon, Arsène, additional, Krawczyk, Karolina, additional, Krishnan, Sudhir, additional, Krishnan, Vinothini, additional, Kruglova, Oksana, additional, Kumar, Ashok, additional, Kumar, Deepali, additional, Kumar, Ganesh, additional, Kumar, Mukesh, additional, Kumar Vecham, Pavan, additional, Kuriakose, Dinesh, additional, Kurtzman, Ethan, additional, Kusumastuti, Neurinda Permata, additional, Kutsogiannis, Demetrios, additional, Kutsyna, Galyna, additional, Kyriakoulis, Konstantinos, additional, Lachatre, Marie, additional, Lacoste, Marie, additional, Laffey, John G., additional, Lagrange, Marie, additional, Laine, Fabrice, additional, Lairez, Olivier, additional, Lakhey, Sanjay, additional, Lalueza, Antonio, additional, Lambert, Marc, additional, Lamontagne, François, additional, Langelot-Richard, Marie, additional, Langlois, Vincent, additional, Lantang, Eka Yudha, additional, Lanza, Marina, additional, Laouénan, Cédric, additional, Laribi, Samira, additional, Lariviere, Delphine, additional, Lasry, Stéphane, additional, Latif, Naveed, additional, Launay, Odile, additional, Laureillard, Didier, additional, Lavie-Badie, Yoan, additional, Law, Andy, additional, Lawrence, Cassie, additional, Lawrence, Teresa, additional, Le, Minh, additional, Le Bihan, Clément, additional, Le Bris, Cyril, additional, Le Falher, Georges, additional, Le Fevre, Lucie, additional, Le Hingrat, Quentin, additional, Le Maréchal, Marion, additional, Le Mestre, Soizic, additional, Le Moal, Gwenaël, additional, Le Moing, Vincent, additional, Le Nagard, Hervé, additional, Le Turnier, Paul, additional, Leal, Ema, additional, Leal Santos, Marta, additional, Lee, Biing Horng, additional, Lee, Heng Gee, additional, Lee, James, additional, Lee, Su Hwan, additional, Lee, Todd C., additional, Lee, Yi Lin, additional, Leeming, Gary, additional, Lefebvre, Bénédicte, additional, Lefebvre, Laurent, additional, Lefevre, Benjamin, additional, LeGac, Sylvie, additional, Lelievre, Jean-Daniel, additional, Lellouche, François, additional, Lemaignen, Adrien, additional, Lemee, Véronique, additional, Lemeur, Anthony, additional, Lemmink, Gretchen, additional, Lene, Ha Sha, additional, Lennon, Jenny, additional, León, Rafael, additional, Leone, Marc, additional, Leone, Michela, additional, Lepiller, Quentin, additional, Lescure, François-Xavier, additional, Lesens, Olivier, additional, Lesouhaitier, Mathieu, additional, Lester-Grant, Amy, additional, Levy, Bruno, additional, Levy, Yves, additional, Levy-Marchal, Claire, additional, Lewandowska, Katarzyna, additional, L'Her, Erwan, additional, Li Bassi, Gianluigi, additional, Liang, Janet, additional, Liaquat, Ali, additional, Liegeon, Geoffrey, additional, Lim, Kah Chuan, additional, Lim, Wei Shen, additional, Lima, Chantre, additional, Lina, Bruno, additional, Lina, Lim, additional, Lind, Andreas, additional, Lingas, Guillaume, additional, Lion-Daolio, Sylvie, additional, Lissauer, Samantha, additional, Liu, Keibun, additional, Livrozet, Marine, additional, Lizotte, Patricia, additional, Loforte, Antonio, additional, Lolong, Navy, additional, Loon, Leong Chee, additional, Lopes, Diogo, additional, Lopez-Colon, Dalia, additional, Loschner, Anthony L., additional, Loubet, Paul, additional, Loufti, Bouchra, additional, Louis, Guillame, additional, Lourenco, Silvia, additional, Lovelace-Macon, Lara, additional, Low, Lee Lee, additional, Lowik, Marije, additional, Loy, Jia Shyi, additional, Lucet, Jean Christophe, additional, Lumbreras Bermejo, Carlos, additional, Luna, Carlos M., additional, Lungu, Olguta, additional, Luong, Liem, additional, Luque, Nestor, additional, Luton, Dominique, additional, Lwin, Nilar, additional, Lyons, Ruth, additional, Maasikas, Olavi, additional, Mabiala, Oryane, additional, MacDonald, Samual, additional, MacDonald, Sarah, additional, Machado, Moïse, additional, Macheda, Gabriel, additional, Macias Sanchez, Juan, additional, Madhok, Jai, additional, Maestro de la Calle, Guillermo, additional, Mahieu, Rafael, additional, Mahy, Sophie, additional, Maia, Ana Raquel, additional, Maier, Lars S., additional, Maillet, Mylène, additional, Maitre, Thomas, additional, Malfertheiner, Maximilian, additional, Malik, Nadia, additional, Mallon, Paddy, additional, Maltez, Fernando, additional, Malvy, Denis, additional, Manda, Victoria, additional, Mandei, Jose M., additional, Mandelbrot, Laurent, additional, Manetta, Frank, additional, Mangal, Kishore, additional, Mankikian, Julie, additional, Manning, Edmund, additional, Manuel, Aldric, additional, Maria Sant`Ana Malaque, Ceila, additional, Marino, Daniel, additional, Marino, Flávio, additional, Markowicz, Samuel, additional, Maroun Eid, Charbel, additional, Marques, Ana, additional, Marquis, Catherine, additional, Marsh, Brian, additional, Marsh, Laura, additional, Marshal, Megan, additional, Marshall, John, additional, Martelli, Celina Turchi, additional, Martin, Dori-Ann, additional, Martin, Emily, additional, Martin-Blondel, Guillaume, additional, Martinelli, Alessandra, additional, Martin-Loeches, Ignacio, additional, Martinot, Martin, additional, Martin-Quiros, Alejandro, additional, Martins, Ana, additional, Martins, João, additional, Martins, Nuno, additional, Martins Rego, Caroline, additional, Martucci, Gennaro, additional, Martynenko, Olga, additional, Marwali, Eva Miranda, additional, Marzukie, Marsilla, additional, Masa Jimenez, Juan Fernado, additional, Maslove, David, additional, Mason, Phillip, additional, Mason, Sabina, additional, Masood, Sobia, additional, Mat Nor, Basri, additional, Matan, Moshe, additional, Mateus Fernandes, Henrique, additional, Mathew, Meghena, additional, Mathieu, Daniel, additional, Mattei, Mathieu, additional, Matulevics, Romans, additional, Maulin, Laurence, additional, Maxwell, Michael, additional, Maynar, Javier, additional, Mazzoni, Thierry, additional, Mc Sweeney, Lisa, additional, McAndrew, Lorraine, additional, McArthur, Colin, additional, McCarthy, Aine, additional, McCarthy, Anne, additional, McCloskey, Colin, additional, McConnochie, Rachael, additional, McDermott, Sherry, additional, McDonald, Sarah E., additional, McElroy, Aine, additional, McElwee, Samuel, additional, McEneany, Victoria, additional, McEvoy, Natalie, additional, McGeer, Allison, additional, McKay, Chris, additional, McKeown, Johnny, additional, McLean, Kenneth A., additional, McNally, Paul, additional, McNicholas, Bairbre, additional, McPartlan, Elaine, additional, Meaney, Edel, additional, Mear-Passard, Cécile, additional, Mechlin, Maggie, additional, Meher, Maqsood, additional, Mehkri, Omar, additional, Mele, Ferruccio, additional, Melo, Luis, additional, Memon, Kashif, additional, Mendes, Joao Joao, additional, Menkiti, Ogechukwu, additional, Menon, Kusum, additional, Mentré, France, additional, Mentzer, Alexander J., additional, Mercier, Emmanuelle, additional, Mercier, Noémie, additional, Merckx, Antoine, additional, Mergeay-Fabre, Mayka, additional, Mergler, Blake, additional, Merson, Laura, additional, Mesquita, António, additional, Metwally, Osama, additional, Meybeck, Agnès, additional, Meyer, Dan, additional, Meynert, Alison M., additional, Meysonnier, Vanina, additional, Meziane, Amina, additional, Mezidi, Mehdi, additional, Michelagnoli, Giuliano, additional, Michelanglei, Céline, additional, Michelet, Isabelle, additional, Mihelis, Efstathia, additional, Mihnovit, Vladislav, additional, Miranda-Maldonado, Hugo, additional, Misnan, Nor Arisah, additional, Mohamed, Nik Nur Eliza, additional, Mohamed, Tahira Jamal, additional, Moin, Asma, additional, Molina, David, additional, Molinos, Elena, additional, Molloy, Brenda, additional, Mone, Mary, additional, Monteiro, Agostinho, additional, Montes, Claudia, additional, Montrucchio, Giorgia, additional, Moore, Sarah, additional, Moore, Shona C., additional, Morales Cely, Lina, additional, Moro, Lucia, additional, Morocho Tutillo, Diego Rolando, additional, Morton, Ben, additional, Motherway, Catherine, additional, Motos, Ana, additional, Mouquet, Hugo, additional, Mouton Perrot, Clara, additional, Moyet, Julien, additional, Mudara, Caroline, additional, Mufti, Aisha Kalsoom, additional, Muh, Ng Yong, additional, Muhamad, Dzawani, additional, Mullaert, Jimmy, additional, Muller, Fredrik, additional, Müller, Karl Erik, additional, Munblit, Daniel, additional, Muneeb, Syed, additional, Munir, Nadeem, additional, Munshi, Laveena, additional, Murphy, Aisling, additional, Murphy, Lorna, additional, Murris, Marlène, additional, Murthy, Srinivas, additional, Musaab, Himed, additional, Muyandy, Gugapriyaa, additional, Myrodia, Dimitra Melia, additional, N, Namra, additional, Nagpal, Dave, additional, Nagrebetsky, Alex, additional, Narasimhan, Mangala, additional, Narayanan, Nageswaran, additional, Nasim Khan, Rashid, additional, Nazerali-Maitland, Alasdair, additional, Neant, Nadège, additional, Neb, Holger, additional, Nekliudov, Nikita A, additional, Nelwan, Erni, additional, Neto, Raul, additional, Neumann, Emily, additional, Neves, Bernardo, additional, Ng, Pauline Yeung, additional, Nghi, Anthony, additional, Nguyen, Duc, additional, Ni Choileain, Orna, additional, Ni Leathlobhair, Niamh, additional, Nichol, Alistair, additional, Nitayavardhana, Prompak, additional, Nonas, Stephanie, additional, Noordin, Nurul Amani Mohd, additional, Noret, Marion, additional, Norharizam, Nurul Faten Izzati, additional, Norman, Lisa, additional, Notari, Alessandra, additional, Noursadeghi, Mahdad, additional, Nowicka, Karolina, additional, Nowinski, Adam, additional, Nseir, Saad, additional, Nunez, Jose I, additional, Nurnaningsih, Nurnaningsih, additional, Nyamankolly, Elsa, additional, O Brien, Fionnuala, additional, O'Callaghan, Annmarie, additional, Occhipinti, Giovanna, additional, OConnor, Derbrenn, additional, O'Donnell, Max, additional, Ogston, Tawnya, additional, Ogura, Takayuki, additional, Oh, Tak-Hyuk, additional, O'Halloran, Sophie, additional, O'Hearn, Katie, additional, Ohshimo, Shinichiro, additional, Oldakowska, Agnieszka, additional, Oliveira, João, additional, Oliveira, Larissa, additional, Olliaro, Piero L., additional, O'Neil, Conar, additional, Ong, David S.Y., additional, Ong, Jee Yan, additional, Oosthuyzen, Wilna, additional, Opavsky, Anne, additional, Openshaw, Peter, additional, Orakzai, Saijad, additional, Orozco-Chamorro, Claudia Milena, additional, Orquera, Andrés, additional, Ortoleva, Jamel, additional, Osatnik, Javier, additional, O'Shea, Linda, additional, O'Sullivan, Miriam, additional, Othman, Siti Zubaidah, additional, Ouamara, Nadia, additional, Ouissa, Rachida, additional, Owyang, Clark, additional, Oziol, Eric, additional, Pabasara, H M Upulee, additional, Pagadoy, Maïder, additional, Pages, Justine, additional, Palacios, Amanda, additional, Palacios, Mario, additional, Palmarini, Massimo, additional, Panarello, Giovanna, additional, Panda, Prasan Kumar, additional, Paneru, Hem, additional, Pang, Lai Hui, additional, Panigada, Mauro, additional, Pansu, Nathalie, additional, Papadopoulos, Aurélie, additional, Parke, Rachael, additional, Parker, Melissa, additional, Parra, Briseida, additional, Parrini, Vieri, additional, Pasha, Taha, additional, Pasquier, Jérémie, additional, Pastene, Bruno, additional, Patauner, Fabian, additional, Patel, Junaid, additional, Pathmanathan, Mohan Dass, additional, Patrão, Luís, additional, Patricio, Patricia, additional, Patrier, Juliette, additional, Patterson, Lisa, additional, Pattnaik, Rajyabardhan, additional, Paul, Christelle, additional, Paul, Mical, additional, Paulos, Jorge, additional, Paxton, William A., additional, Payen, Jean-François, additional, Peariasamy, Kalaiarasu, additional, Pedrera Jiménez, Miguel, additional, Peek, Giles J., additional, Peelman, Florent, additional, Peiffer-Smadja, Nathan, additional, Peigne, Vincent, additional, Pejkovska, Mare, additional, Pelosi, Paolo, additional, Peltan, Ithan D., additional, Pereira, Rui, additional, Perez, Daniel, additional, Periel, Luis, additional, Perpoint, Thomas, additional, Pesenti, Antonio, additional, Pestre, Vincent, additional, Petrou, Lenka, additional, Petrov-Sanchez, Ventzislava, additional, Pettersen, Frank Olav, additional, Peytavin, Gilles, additional, Pharand, Scott, additional, Piagnerelli, Michael, additional, Picard, Walter, additional, Picone, Olivier, additional, Piero, Maria de, additional, Pierobon, Carola, additional, Piersma, Djura, additional, Pimentel, Carlos, additional, Pinto, Raquel, additional, Pires, Catarina, additional, Pironneau, Isabelle, additional, Piroth, Lionel, additional, Pius, Riinu, additional, Piva, Simone, additional, Plantier, Laurent, additional, Plotkin, Daniel, additional, Png, Hon Shen, additional, Poissy, Julien, additional, Pokeerbux, Ryadh, additional, Pokorska-Spiewak, Maria, additional, Poli, Sergio, additional, Pollakis, Georgios, additional, Ponscarme, Diane, additional, Popielska, Jolanta, additional, Post, Andra-Maris, additional, Postma, Douwe F., additional, Povoa, Pedro, additional, Póvoas, Diana, additional, Powis, Jeff, additional, Prapa, Sofia, additional, Preau, Sébastien, additional, Prebensen, Christian, additional, Preiser, Jean-Charles, additional, Prinssen, Anton, additional, Pritchard, Mark G., additional, Priyadarshani, Gamage Dona Dilanthi, additional, Proença, Lucia, additional, Pudota, Sravya, additional, Puéchal, Oriane, additional, Pujo Semedi, Bambang, additional, Pulicken, Mathew, additional, Puntoni, Matteo, additional, Purcell, Gregory, additional, Quesada, Luisa, additional, Quinones-Cardona, Vilmaris, additional, Quirós González, Víctor, additional, Quist-Paulsen, Else, additional, Quraishi, Mohammed, additional, Rabaa, Maia, additional, Rabaud, Christian, additional, Rabindrarajan, Ebenezer, additional, Rafael, Aldo, additional, Rafiq, Marie, additional, Ragazzo, Gabrielle, additional, Rahman, Ahmad Kashfi Haji Ab, additional, Rahman, Rozanah Abd, additional, Rahutullah, Arsalan, additional, Rainieri, Fernando, additional, Rajahram, Giri Shan, additional, Rajapakse, Nipunie, additional, Ralib, Azrina, additional, Ramakrishnan, Nagarajan, additional, Ramanathan, Kollengode, additional, Ramli, Ahmad Afiq, additional, Rammaert, Blandine, additional, Ramos, Grazielle Viana, additional, Rana, Asim, additional, Rangappa, Rajavardhan, additional, Ranjan, Ritika, additional, Rapp, Christophe, additional, Rashan, Aasiyah, additional, Rashan, Thalha, additional, Rasheed, Ghulam, additional, Rasmin, Menaldi, additional, Rätsep, Indrek, additional, Rau, Cornelius, additional, Ravi, Tharmini, additional, Raza, Ali, additional, Real, Andre, additional, Rebaudet, Stanislas, additional, Redl, Sarah, additional, Reeve, Brenda, additional, Rehan, Ali, additional, Rehman, Attaur, additional, Reid, Liadain, additional, Reikvam, Dag Henrik, additional, Reis, Renato, additional, Rello, Jordi, additional, Remppis, Jonathan, additional, Remy, Martine, additional, Ren, Hongru, additional, Renk, Hanna, additional, Resende, Liliana, additional, Resseguier, Anne-Sophie, additional, Revest, Matthieu, additional, Rewa, Oleksa, additional, Reyes, Luis Felipe, additional, Reyes, Tiago, additional, Ribeiro, Maria Ines, additional, Richardson, David, additional, Richardson, Denise, additional, Richier, Laurent, additional, Ridzuan, Siti Nurul Atikah Ahmad, additional, Riera, Jordi, additional, Rios, Ana L, additional, Rishu, Asgar, additional, Rispal, Patrick, additional, Risso, Karine, additional, Rivera Nuñez, Maria Angelica, additional, Rizer, Nicholas, additional, Robb, Doug, additional, Robba, Chiara, additional, Roberto, André, additional, Roberts, Stephanie, additional, Robertson, David L., additional, Robineau, Olivier, additional, Roche-Campo, Ferran, additional, Rodari, Paola, additional, Rodeia, Simão, additional, Rodriguez Abreu, Julia, additional, Roessler, Bernhard, additional, Roger, Claire, additional, Roger, Pierre-Marie, additional, Roilides, Emmanuel, additional, Rojek, Amanda, additional, Romaru, Juliette, additional, Roncon-Albuquerque Jr, Roberto, additional, Roriz, Mélanie, additional, Rosa-Calatrava, Manuel, additional, Rose, Michael, additional, Rosenberger, Dorothea, additional, Rossanese, Andrea, additional, Rossetti, Matteo, additional, Rossignol, Bénédicte, additional, Rossignol, Patrick, additional, Rousset, Stella, additional, Roy, Carine, additional, Roze, Benoît, additional, Rusmawatiningtyas, Desy, additional, Russell, Clark D., additional, Ryan, Maeve, additional, Ryan, Maria, additional, Ryckaert, Steffi, additional, Rygh Holten, Aleksander, additional, Saba, Isabela, additional, Sadaf, Sairah, additional, Sadat, Musharaf, additional, Sahraei, Valla, additional, Saint-Gilles, Maximilien, additional, Sakiyalak, Pranya, additional, Salahuddin, Nawal, additional, Salazar, Leonardo, additional, Saleem, Jodat, additional, Sales, Gabriele, additional, Sallaberry, Stéphane, additional, Salmon Gandonniere, Charlotte, additional, Salvator, Hélène, additional, Sanchez, Olivier, additional, Sánchez Choez, Xavier, additional, Sanchez de Oliveira, Kizy, additional, Sanchez-Miralles, Angel, additional, Sancho-Shimizu, Vanessa, additional, Sandhu, Gyan, additional, Sandhu, Zulfiqar, additional, Sandrine, Pierre-François, additional, Sandulescu, Oana, additional, Santos, Marlene, additional, Sarfo-Mensah, Shirley, additional, Sarmento Banheiro, Bruno, additional, Sarmiento, Iam Claire E., additional, Sarton, Benjamine, additional, Satyapriya, Sree, additional, Satyawati, Rumaisah, additional, Saviciute, Egle, additional, Savio, Raymond, additional, Savvidou, Parthena, additional, Saw, Yen Tsen, additional, Schaffer, Justin, additional, Schermer, Tjard, additional, Scherpereel, Arnaud, additional, Schneider, Marion, additional, Schroll, Stephan, additional, Schwameis, Michael, additional, Schwartz, Gary, additional, Scott, Janet T., additional, Scott-Brown, James, additional, Sedillot, Nicholas, additional, Seitz, Tamara, additional, Selvanayagam, Jaganathan, additional, Selvarajoo, Mageswari, additional, Semaille, Caroline, additional, Semple, Malcolm G., additional, Senian, Rasidah Bt, additional, Senneville, Eric, additional, Sepulveda, Claudia, additional, Sequeira, Filipa, additional, Sequeira, Tânia, additional, Serpa Neto, Ary, additional, Serrano Balazote, Pablo, additional, Shadowitz, Ellen, additional, Shahidan, Syamin Asyraf, additional, Shahnaz Hasan, Mohd, additional, Shamsah, Mohammad, additional, Shankar, Anuraj, additional, Sharjeel, Shaikh, additional, Sharma, Pratima, additional, Shaw, Catherine A., additional, Shaw, Victoria, additional, Shi, Haixia, additional, Shiban, Nisreen, additional, Shiekh, Mohiuddin, additional, Shiga, Takuya, additional, Shime, Nobuaki, additional, Shimizu, Hiroaki, additional, Shimizu, Keiki, additional, Shimizu, Naoki, additional, Shindo, Nahoko, additional, Shrapnel, Sally, additional, Shum, Hoi Ping, additional, Si Mohammed, Nassima, additional, Siang, Ng Yong, additional, Sibiude, Jeanne, additional, Siddiqui, Atif, additional, Sigfrid, Louise, additional, Sillaots, Piret, additional, Silva, Catarina, additional, Silva, Maria Joao, additional, Silva, Rogério, additional, Sim Lim Heng, Benedict, additional, Sin, Wai Ching, additional, Singh, Budha Charan, additional, Singh, Punam, additional, Sitompul, Pompini Agustina, additional, Sivam, Karisha, additional, Skogen, Vegard, additional, Smith, Sue, additional, Smood, Benjamin, additional, Smyth, Coilin, additional, Smyth, Michelle, additional, Snacken, Morgane, additional, So, Dominic, additional, Soh, Tze Vee, additional, Solis, Monserrat, additional, Solomon, Joshua, additional, Solomon, Tom, additional, Somers, Emily, additional, Sommet, Agnès, additional, Song, Myung Jin, additional, Song, Rima, additional, Song, Tae, additional, Song Chia, Jack, additional, Sonntagbauer, Michael, additional, Soom, Azlan Mat, additional, Sotto, Alberto, additional, Soum, Edouard, additional, Sousa, Ana Chora, additional, Sousa, Marta, additional, Sousa Uva, Maria, additional, Souza-Dantas, Vicente, additional, Sperry, Alexandra, additional, Spinuzza, Elisabetta, additional, Sri Darshana, B. P. Sanka Ruwan, additional, Sriskandan, Shiranee, additional, Stabler, Sarah, additional, Staudinger, Thomas, additional, Stecher, Stephanie-Susanne, additional, Steinsvik, Trude, additional, Stienstra, Ymkje, additional, Stiksrud, Birgitte, additional, Stolz, Eva, additional, Stone, Amy, additional, Streinu-Cercel, Adrian, additional, Streinu-Cercel, Anca, additional, Strudwick, Samantha, additional, Stuart, Ami, additional, Stuart, David, additional, Subekti, Decy, additional, Suen, Gabriel, additional, Suen, Jacky Y., additional, Sukumar, Prasanth, additional, Sultana, Asfia, additional, Summers, Charlotte, additional, Supic, Dubravka, additional, Suppiah, Deepashankari, additional, Surovcová, Magdalena, additional, Suwarti, Suwarti, additional, Svistunov, Andrey A, additional, Syahrin, Sarah, additional, Syrigos, Konstantinos, additional, Sztajnbok, Jaques, additional, Szuldrzynski, Konstanty, additional, Tabrizi, Shirin, additional, Taccone, Fabio S., additional, Tagherset, Lysa, additional, Taib, Shahdattul Mawarni, additional, Talarek, Ewa, additional, Taleb, Sara, additional, Talsma, Jelmer, additional, Tampubolon, Maria Lawrensia, additional, Tan, Kim Keat, additional, Tan, Le Van, additional, Tan, Yan Chyi, additional, Tanaka, Clarice, additional, Tanaka, Hiroyuki, additional, Tanaka, Taku, additional, Taniguchi, Hayato, additional, Tanveer, Hussain, additional, Taqdees, Huda, additional, Taqi, Arshad, additional, Tardivon, Coralie, additional, Tattevin, Pierre, additional, Taufik, M Azhari, additional, Tawfik, Hassan, additional, Tedder, Richard S., additional, Tee, Tze Yuan, additional, Teixeira, João, additional, Tejada, Sofia, additional, Tellier, Marie-Capucine, additional, Teoh, Sze Kye, additional, Teotonio, Vanessa, additional, Téoulé, François, additional, Terpstra, Pleun, additional, Terrier, Olivier, additional, Terzi, Nicolas, additional, Tessier-Grenier, Hubert, additional, Tey, Adrian, additional, Thabit, Alif Adlan Mohd, additional, Tham, Zhang Duan, additional, Thangavelu, Suvintheran, additional, Thibault, Vincent, additional, Thiberville, Simon-Djamel, additional, Thill, Benoît, additional, Thirumanickam, Jananee, additional, Thompson, Shaun, additional, Thomson, David, additional, Thomson, Emma C., additional, Thurai, Surain Raaj Thanga, additional, Thuy, Duong Bich, additional, Thwaites, Ryan S., additional, Tierney, Paul, additional, Tieroshyn, Vadim, additional, Timashev, Peter S, additional, Timsit, Jean-François, additional, Tirupakuzhi Vijayaraghavan, Bharath Kumar, additional, Tissot, Noémie, additional, Toh, Jordan Zhien Yang, additional, Toki, Maria, additional, Tolppa, Timo, additional, Tonby, Kristian, additional, Tonnii, Sia Loong, additional, Torres, Antoni, additional, Torres, Margarida, additional, Torres Santos-Olmo, Rosario Maria, additional, Torres-Zevallos, Hernando, additional, Towers, Michael, additional, Trapani, Tony, additional, Traynor, Damien, additional, Treoux, Théo, additional, Trieu, Huynh Trung, additional, Tripathy, Swagata, additional, Tromeur, Cécile, additional, Trontzas, Ioannis, additional, Trouillon, Tiffany, additional, Truong, Jeanne, additional, Tual, Christelle, additional, Tubiana, Sarah, additional, Tuite, Helen, additional, Turmel, Jean-Marie, additional, Turtle, Lance C.W., additional, Tveita, Anders, additional, Twardowski, Pawel, additional, Uchiyama, Makoto, additional, Udayanga, PG Ishara, additional, Udy, Andrew, additional, Ullrich, Roman, additional, Umer, Zubair, additional, Uribe, Alberto, additional, Usman, Asad, additional, Vajdovics, Cristinava, additional, Val-Flores, Luís, additional, Valle, Ana Luiza, additional, Valran, Amélie, additional, Van de Velde, Stijn, additional, van den Berge, Marcel, additional, van der Feltz, Machteld, additional, van der Valk, Paul, additional, Van Der Vekens, Nicky, additional, Van der Voort, Peter, additional, Van Der Werf, Sylvie, additional, van Dyk, Marlice, additional, van Gulik, Laura, additional, Van Hattem, Jarne, additional, van Lelyveld, Steven, additional, van Netten, Carolien, additional, Van Twillert, Gitte, additional, van Veen, Ilonka, additional, Vanel, Noémie, additional, Vanoverschelde, Henk, additional, Varghese, Pooja, additional, Varrone, Michael, additional, Vasudayan, Shoban Raj, additional, Vauchy, Charline, additional, Vaughan, Helen, additional, Veeran, Shaminee, additional, Veislinger, Aurélie, additional, Vencken, Sebastian, additional, Ventura, Sara, additional, Verbon, Annelies, additional, Vidal, José Ernesto, additional, Vieira, César, additional, Vijayan, Deepak, additional, Villanueva, Joy Ann, additional, Villar, Judit, additional, Villeneuve, Pierre-Marc, additional, Villoldo, Andrea, additional, Vinh Chau, Nguyen Van, additional, Visseaux, Benoit, additional, Visser, Hannah, additional, Vitiello, Chiara, additional, Vonkeman, Harald, additional, Vuotto, Fanny, additional, Wahab, Noor Hidayu, additional, Wahab, Suhaila Abdul, additional, Wahid, Nadirah Abdul, additional, Wainstein, Marina, additional, Wan Muhd Shukeri, Wan Fadzlina, additional, Wang, Chih-Hsien, additional, Webb, Steven Anthony, additional, Wei, Jia, additional, Weil, Katharina, additional, Wen, Tan Pei, additional, Wesselius, Sanne, additional, West, T. Eoin, additional, Wham, Murray, additional, Whelan, Bryan, additional, White, Nicole, additional, Wicky, Paul Henri, additional, Wiedemann, Aurélie, additional, Wijaya, Surya Otto, additional, Wille, Keith, additional, Willems, Suzette, additional, Williams, Virginie, additional, Wils, Evert-Jan, additional, Wing Yiu, Ng, additional, Wong, Calvin, additional, Wong, Teck Fung, additional, Wong, Xin Ci, additional, Wong, Yew Sing, additional, Xian, Gan Ee, additional, Xian, Lim Saio, additional, Xuan, Kuan Pei, additional, Xynogalas, Ioannis, additional, Yacoub, Sophie, additional, Yakop, Siti Rohani Binti Mohd, additional, Yamazaki, Masaki, additional, Yazdanpanah, Yazdan, additional, Yee Liang Hing, Nicholas, additional, Yelnik, Cécile, additional, Yeoh, Chian Hui, additional, Yerkovich, Stephanie, additional, Yokoyama, Toshiki, additional, Yonis, Hodane, additional, Yousif, Obada, additional, Yuliarto, Saptadi, additional, Zaaqoq, Akram, additional, Zabbe, Marion, additional, Zacharowski, Kai, additional, Zahid, Masliza, additional, Zahran, Maram, additional, Zaidan, Nor Zaila Binti, additional, Zambon, Maria, additional, Zambrano, Miguel, additional, Zanella, Alberto, additional, Zawadka, Konrad, additional, Zaynah, Nurul, additional, Zayyad, Hiba, additional, Zoufaly, Alexander, additional, and Zucman, David, additional
Published: 2021
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30. Aetiology of acute respiratory infection in preschool children requiring hospitalisation in Europe—results from the PED-MERMAIDS multicentre case–control study

Author: Kohns Vasconcelos, Malte, primary, Loens, Katherine, additional, Sigfrid, Louise, additional, Iosifidis, Elias, additional, Epalza, Cristina, additional, Donà, Daniele, additional, Matheeussen, Veerle, additional, Papachristou, Savvas, additional, Roilides, Emmanuel, additional, Gijon, Manuel, additional, Rojo, Pablo, additional, Minotti, Chiara, additional, Da Dalt, Liviana, additional, Islam, Samsul, additional, Jarvis, Jessica, additional, Syggelou, Aggeliki, additional, Tsolia, Maria, additional, Nyirenda Nyang’wa, Maggie, additional, Keers, Sophie, additional, Renk, Hanna, additional, Gemmel, Anna-Lena, additional, D’Amore, Carmen, additional, Ciofi degli Atti, Marta, additional, Rodríguez-Tenreiro Sánchez, Carmen, additional, Martinón-Torres, Federico, additional, Burokienė, Sigita, additional, Goetghebuer, Tessa, additional, Spoulou, Vana, additional, Riordan, Andrew, additional, Calvo, Cristina, additional, Gkentzi, Despoina, additional, Hufnagel, Markus, additional, Openshaw, Peter J, additional, de Jong, Menno D, additional, Koopmans, Marion, additional, Goossens, Herman, additional, Ieven, Margareta, additional, Fraaij, Pieter L A, additional, Giaquinto, Carlo, additional, Bielicki, Julia A, additional, Horby, Peter, additional, and Sharland, Michael, additional
Published: 2021
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31. A conceptual approach to the rationale for SARS-CoV-2 vaccine allocation prioritisation

Author: Kohns Vasconcelos, Malte, primary, Marazia, Chantal, additional, Koniordou, Markela, additional, Fangerau, Heiner, additional, Drexler, Ingo, additional, and Afum-Adjei Awuah, Anthony, additional
Published: 2021
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32. Paediatric primary care in Germany during the early COVID-19 pandemic: the calm before the storm

Author: Kohns Vasconcelos, Malte, primary, Weil, Katharina, additional, Vesterling-Hörner, Daniela, additional, Klemm, Mehrsad, additional, el Scheich, Tarik, additional, Renk, Hanna, additional, Remke, Katharina, additional, and Bosse, Hans Martin, additional
Published: 2021
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33. Mycoplasma pneumoniae: gone forever?

Author: Pereyre, Sabine, Bébéar, Cécile, Gardette, Marie, Hénin, Nadège, Wagner, Noémie, Fischer, Adrien, Vitale, Alessandra, Kessler, Julie, Andreutti, Corinne, Greub, Gilbert, Zimmermann, Petra, Agyeman, Philipp K A, Aebi, Christoph, Buettcher, Michael, Hostettler, Marisa, Kottanattu, Lisa, Gaia, Valeria, Imkamp, Frank, Egli, Adrian, Berger, Christoph, Sidorov, Semjon, Tilen, Romy, Niederer-Loher, Anita, Barbey, Florence, Heininger, Ulrich, Ivan, Branislav, Papan, Cihan, Becker, Sören L, Forster, Johannes, Kohns Vasconcelos, Malte, Henrich, Birgit, MacKenzie, Colin R, Bossuyt, Nathalie, Vermeulen, Melissa, Matheeussen, Veerle, van Westreenen, Mireille, Verkaik, Nelianne J, Vogel, Marius, van Rossum, Annemarie M C, Afshar, Baharak, Uldum, Søren Anker, Emborg, Hanne-Dorthe, Gullsby, Karolina, Laine, Miia, Peltola, Ville, Heinonen, Santtu, Døllner, Henrik, Width, Frode Gran, Christensen, Andreas, Buonsenso, Danilo, Rodrigues, Fernanda M P, Rodrigues, Jorge, Tsantila, Katerina, Matsas, Minos, Kalogera, Eleni, Petridou, Evangelia, Kopsidas, Ioannis, Keše, Darja, Nir-Paz, Ran, Elinav, Hila, Michael-Gayego, Ayelet, Oishi, Tomohiro, Saraya, Takeshi, Hsieh, Yu-Chia, Wu, Tsung Hua, Maiwald, Matthias, Loo, Liat Hui, Sagar, Tanu, Chaudhry, Rama, Kociolek, Larry K, Rodríguez, Nadia, Lorenz, David, Blakiston, Matthew R, Meyer Sauteur, Patrick M, and Beeton, Michael L
Published: 2023
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34. Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired pneumonia: a trial protocol for the KIDS-STEP trial

Author: Kohns Vasconcelos, Malte, primary, Meyer Sauteur, Patrick M, additional, Santoro, Regina, additional, Coslovsky, Michael, additional, Lurà, Marco, additional, Keitel, Kristina, additional, Wachinger, Tanja, additional, Beglinger, Svetlana, additional, Heininger, Ulrich, additional, van den Anker, Johannes, additional, and Bielicki, Julia Anna, additional
Published: 2020
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35. SARS-CoV-2 testing and infection control strategies in European paediatric emergency departments during the first wave of the pandemic

Author: Kohns Vasconcelos, Malte, primary, Renk, Hanna, additional, Popielska, Jolanta, additional, Nyirenda Nyang’wa, Maggie, additional, Burokiene, Sigita, additional, Gkentzi, Despoina, additional, Gowin, Ewelina, additional, Donà, Daniele, additional, Villanueva-Medina, Sara, additional, Riordan, Andrew, additional, Hufnagel, Markus, additional, Eisen, Sarah, additional, Da Dalt, Liviana, additional, Giaquinto, Carlo, additional, and Bielicki, Julia A., additional
Published: 2020
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36. Children living with HIV in Europe: do migrants have worse treatment outcomes?

Author: Chappell, Elizabeth, Kohns Vasconcelos, Malte, Goodall, Ruth L., Galli, Luisa, Goetghebuer, Tessa, Noguera‐Julian, Antoni, Rodrigues, Laura C., Scherpbier, Henriette, Smit, Colette, Bamford, Alasdair, Crichton, Siobhan, Navarro, Marissa Luisa, Ramos, Jose T., Warszawski, Josiane, Spolou, Vana, Chiappini, Elena, Venturini, Elisabetta, Prata, Filipa, Kahlert, Christian, and Marczynska, Magdalena
Subjects: *NOMADS, *HIV-positive persons, *TREATMENT effectiveness, *CHILDREN, *EVALUATION
Abstract: Objectives: To assess the effect of migrant status on treatment outcomes among children living with HIV in Europe. Methods: Children aged < 18 years at the start of antiretroviral therapy (ART) in European paediatric HIV observational cohorts where ≥ 5% of children were migrants (defined as born abroad) were included. Three outcomes were considered: (i) severe immunosuppression‐for‐age; (ii) viraemic viral load (≥ 400 copies/mL) at 1 year after ART initiation; and (iii) AIDS/death after ART initiation. The effect of migrant status was assessed using univariable and multivariable logistic and Cox models. Results: Of 2620 children included across 12 European countries, 56% were migrants. At ART initiation, migrant children were older than domestic‐born children (median 6.1 vs. 0.9 years, p < 0.001), with slightly higher proportions being severely immunocompromised (35% vs. 33%) and with active tuberculosis (2% vs. 1%), but a lower proportion with an AIDS diagnosis (14% vs. 19%) (all p < 0.001). At 1 year after beginning ART, a lower proportion of migrant children were viraemic (18% vs. 24%) but there was no difference in multivariable analysis (p = 0.702), and no difference in severe immunosuppression (p = 0.409). However, there was a trend towards higher risk of AIDS/death in migrant children (adjusted hazard ratio = 1.51, 95% confidence interval: 0.96–2.38, p = 0.072). Conclusions: After adjusting for characteristics at ART initiation, migrant children have virological and immunological outcomes at 1 year of ART that are comparable to those who are domestic‐born, possibly indicating equity in access to healthcare in Europe. However, there was some evidence of a difference in AIDS‐free survival, which warrants further monitoring. [ABSTRACT FROM AUTHOR]
Published: 2022
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37. The effect of remote ischaemic preconditioning on microRNA expression in rat myocardium in vivo

Author: Kohns Vasconcelos, Malte
Published: 2020

38. Mycoplasma pneumoniae beyond the COVID-19 pandemic: where is it?

Author: Pereyre, Sabine, Bébéar, Cécile, Wagner, Noémie, Andreutti, Corinne, Greub, Gilbert, Agyeman, Philipp K A, Aebi, Christoph, Buettcher, Michael, Kottanattu, Lisa, Gaia, Valeria, Imkamp, Frank, Zbinden, Reinhard, Sidorov, Semjon, Niederer-Loher, Anita, Barbey, Florence, Egli, Adrian, Heininger, Ulrich, Schlaeppi, Chloé, Papan, Cihan, Kohns Vasconcelos, Malte, Henrich, Birgit, Mackenzie, Colin, Dumke, Roger, Schneider, Gerlinde, Bossuyt, Nathalie, Vermeulen, Melissa, Loens, Katherine, van Westreenen, Mireille, Verkaik, Nelianne J, van Rossum, Annemarie M C, Day, Jessica, Afshar, Baharak, Peltola, Ville, Heinonen, Santtu, Renko, Marjo, Tapiainen, Terhi, Døllner, Henrik, Rodrigues, Fernanda, Matsas, Minos, Kalogera, Eleni, Petridou, Evangelia, Kopsidas, Ioannis, Zaoutis, Theoklis E, Keše, Darja, Elinav, Hila, Michael-Gayego, Ayelet, Namkoong, Ho, Hsieh, Yu-Chia, Maiwald, Matthias, Loo, Liat Hui, Chaudhry, Rama, Kociolek, Larry K, Rodríguez, Nadia, Lorenz, David, Blakiston, Matthew, Sauteur, Patrick M Meyer, Chalker, Victoria J, Berger, Christoph, Nir-Paz, Ran, and Beeton, Michael L
Published: 2022
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39. Der Einfluss der ischämischen Fernpräkonditionierung auf die Expression von microRNAs im Rattenherz in vivo

Author: Kohns Vasconcelos, Malte and Kohns Vasconcelos, Malte
Published: 2020

40. Medical history and clinical examinations are insufficient to exclude vertical human immunodeficiency virus transmission in healthy, at‐risk adolescents

Author: Kohns Vasconcelos, Malte, primary, Laws, Hans‐Jürgen, additional, Borkhardt, Arndt, additional, and Neubert, Jennifer, additional
Published: 2019
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41. Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.

Author: Walker, Andreas, Houwaart, Torsten, Wienemann, Tobias, Kohns Vasconcelos, Malte, Strelow, Daniel, Senff, Tina, Hülse, Lisanna, Adams, Ortwin, Andree, Marcel, Hauka, Sandra, Feldt, Torsten, Jensen, Björn-Erik, Keitel, Verena, Kindgen-Milles, Detlef, Timm, Jörg, Pfeffer, Klaus, and Dilthey, Alexander T.
Published: 2020
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42. Strikingly Decreased Community-acquired Pneumonia Admissions in Children Despite Open Schools and Day-care Facilities in Switzerland.

Author: Kohns Vasconcelos, Malte, Meyer Sauteur, Patrick M., Keitel, Kristina, Santoro, Regina, Heininger, Ulrich, van den Anker, John, and Bielicki, Julia A.
Published: 2021
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43. Strikingly Decreased Community-acquired Pneumonia Admissions in Children Despite Open Schools and Day-care Facilities in Switzerland

Author: Ulrich Heininger, Regina Santoro, Patrick M. Meyer Sauteur, Malte Kohns Vasconcelos, Kristina Keitel, Julia Bielicki, John N. van den Anker, University of Zurich, and Kohns Vasconcelos, Malte
Subjects: Microbiology (medical), medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MEDLINE, 610 Medicine & health, 2725 Infectious Diseases, Day care, medicine.disease, Pediatrics, Perinatology, 2726 Microbiology (medical), and Child Health, Infectious Diseases, Community-acquired pneumonia, 10036 Medical Clinic, Pediatrics, Perinatology and Child Health, Emergency medicine, medicine, 2735 Pediatrics, Perinatology and Child Health, business
Published: 2021
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44. Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired pneumonia: a trial protocol for the KIDS-STEP trial

Author: Tanja Wachinger, Julia Bielicki, Ulrich Heininger, Svetlana Beglinger, Johannes N. van den Anker, Patrick M. Meyer Sauteur, Marco Lurà, Michael Coslovsky, Malte Kohns Vasconcelos, Kristina Keitel, Regina Santoro, University of Zurich, and Kohns Vasconcelos, Malte
Subjects: Adult, medicine.medical_specialty, 610 Medicine & health, 2700 General Medicine, paediatric infectious disease & immunisation, Placebo, Betamethasone, Superiority Trial, Community-acquired pneumonia, Informed consent, Health care, medicine, accident & emergency medicine, Humans, Multicenter Studies as Topic, Medical prescription, Child, Randomized Controlled Trials as Topic, business.industry, SARS-CoV-2, COVID-19, Paediatrics, General Medicine, Pneumonia, medicine.disease, Treatment Outcome, 10036 Medical Clinic, Emergency medicine, paediatric thoracic medicine, Medicine, Observational study, business, paediatric A&E and ambulatory care, Child, Hospitalized, Switzerland, medicine.drug
Abstract: IntroductionCommunity-acquired pneumonia (CAP) causes around 10 hospitalisations per 1000 child-years, each associated with an average 13 non-routine days experienced and more than 4 parent workdays lost. In adults, steroid treatment shortens time to clinical stabilisation without an increase in complications in patients with CAP. However, despite promising data from observational studies, there is a lack of high-quality evidence for the use of steroids.Methods and analysisThe KIDS-STEP trial is a multicentre, randomised, double-blind, placebo-controlled superiority trial of betamethasone treatment on outcome of hospitalised children with CAP. Children are enrolled in paediatric emergency departments of hospitals across Switzerland and randomised to adjunct oral betamethasone for 2 days or matching placebo in addition to standard of care treatment. The co-primary outcomes are the proportion of children clinically stable 48 hours after randomisation and the proportion of children with CAP-related readmission within 28 days after randomisation. Secondary outcomes include length of hospital stay, time away from routine childcare and healthcare utilisation and total antibiotic prescriptions within 28 days from randomisation.Each of the co-primary outcomes will be analysed separately. We will test clinical stability rates using a proportion test; to test non-inferiority in readmission rates, we will construct 1−α % CI of the estimated difference and test if it contains the pre-defined margin of 7%. Success is conditional on both tests. A simulation-based sample size estimation determined that recruiting 700 patients will ensure a power of 80% for the study.Ethics and disseminationThe trial protocol and materials were approved by ethics committees in Switzerland (lead: Ethikkommission Nordwest und Zentralschweiz) and the regulatory authority Swissmedic. Participants and caregivers provide informed consent prior to study procedures commencing. The trial results will be published in peer-reviewed journals and at national and international conferences. Key messages will also be disseminated via press and social media where appropriate.Trial registration numberNCT03474991 and SNCTP000002864.
Published: 2020
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45. Harmonisation preserves research resources.

Author: Vasconcelos, Malte Kohns, Epalza, Cristina, Renk, Hanna, Tagarro, Alfredo, Bielicki, Julia A, and Kohns Vasconcelos, Malte
Subjects: *MEDICAL care use
Published: 2021
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46. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

Author: Alm E., Broberg E.K., Connor T., Hodcroft E.B., Komissarov A.B., Maurer-Stroh S., Melidou A., Neher R.A., O'Toole A., Pereyaslov D., Beerenwinkel N., Posada-Cespedes S., Jablonski K.P., Ferreira P.F., Topolsky I., Avsic-Zupanc T., Korva M., Poljak M., Zakotnik S., Zorec T.M., Bragstad K., Hungnes O., Stene-Johansen K., Reusken C., Meijer A., Vennema H., Ruiz-Roldan L., Bracho M.A., Garcia-Gonzalez N., Chiner-Oms A., Cancino-Munoz I., Comas I., Goig G.A., Torres-Puente M., Lopez M.G., Martinez-Priego L., D'Auria G., Ruiz-Hueso P., Ferrus-Abad L., de Marco G., Galan-Vendrell I., Carbo-Ramirez S., Ruiz-Rodriguez P., Coscolla M., Polackova K., Kramna L., Cinek O., Richter J., Krashias G., Tryfonos C., Bashiardes S., Koptides D., Christodoulou C., Bartolini B., Gruber C.E., Di Caro A., Castilletti C., Stefani F., Rimoldi S.G., Romeri F., Salerno F., Polesello S., Nagy A., Jirincova H., Vecerova J., Novakova L., Cordey S., Murtskhvaladze M., Kotaria N., Schar T., Beisel C., Vugrek O., Rokic F., Trgovec-Greif L., Jurak I., Rukavina T., Sucic N., Schonning K., Karst S.M., Kirkegaard R.H., Michaelsen T.Y., Sorensen E.A., Knutson S., Brandt J., Le-Quy V., Sorensen T., Petersen C., Pedersen M.S., Larsen S.L., Skov M.N., Rasmussen M., Fonager J., Fomsgaard A., Maksyutov R.A., Gavrilova E.V., Pyankov O.V., Bodnev S.A., Tregubchak T.V., Shvalov A.N., Antonets D.V., Resende P.C., Goya S., Perrin A., Lee R.T., Yadahalli S., Han A.X., Russell C.A., Schmutz S., Zaheri M., Kufner V., Huber M., Trkola A., Antwerpen M., Walter M.C., van der Werf S., Gambaro F., Behillil S., Enouf V., Donati F., Ustinova M., Rovite V., Klovins J., Savicka O., Wienecke-Baldacchino A.K., Ragimbeau C., Fournier G., Mossong J., Aberle S.W., Haukland M., Enkirch T., Advani A., Karlberg M.L., Lindsjo O.K., Broddesson S., Slavikova M., Lickova M., Klempa B., Staronova E., Ticha E., Szemes T., Rusnakova D., Stadler T., Quer J., Anton A., Andres C., Pinana M., Garcia-Cehic D., Pumarola T., Izopet J., Gioula G., Exindari M., Papa A., Chatzidimitriou D., Metallidis S., Pappa S., Macek M., Geryk J., Broz P., Briksi A., Hubacek P., Drevinek P., Zajac M., Kvapil P., Holub M., Kvapilova K., Novotny A., Kasny M., Klempt P., Vapalahti O., Smura T., Sironen T., Selhorst P., Anthony C., Arien K., Simon-Loriere E., Rabalski L., Bienkowska-Szewczyk K., Borges V., Isidro J., Gomes J.P., Guiomar R., Pechirra P., Costa I., Duarte S., Vieira L., Pyrc K., Zuckerman N.S., Turdikulova S., Abdullaev A., Dalimova D., Abdurakhimov A., Tagliabracci A., Alessandrini F., Melchionda F., Onofri V., Turchi C., Bagnarelli P., Menzo S., Caucci S., Di Sante L., Popa A., Genger J.-W., Agerer B., Lercher A., Endler L., Smyth M., Penz T., Schuster M., Senekowitsch M., Laine J., Bock C., Bergthaler A., Shevtsov A., Kalendar R., Ramanculov Y., Graf A., Muenchhoff M., Keppler O.T., Krebs S., Blum H., Marcello A., Licastro D., D'Agaro P., Laubscher F., Vidanovic D., Tesovic B., Volkening J., Clementi N., Mancini N., Rupnik M., Mahnic A., Walker A., Houwaart T., Wienemann T., Vasconcelos M.K., Strelow D., Jensen B.-E.O., Senff T., Hulse L., Adams O., Andree M., Hauka S., Feldt T., Keitel V., Kindgen-Milles D., Timm J., Pfeffer K., Dilthey A.T., Moore C., Ozdarendeli A., Pavel S.T.I., Yetiskin H., Aydin G., Holyavkin C., Uygut M.A., Cevik C., Shchetinin A., Gushchin V., Dinler-Doganay G., Doganay L., Kizilboga-Akgun T., Karacan I., Pancer K., Maes P., Marti-Carreras J., Wawina-Bokalanga T., Vanmechelen B., Thurmer A., Wedde M., Durrwald R., von Kleist M., Drechsel O., Wolff T., Fuchs S., Kmiecinski R., Michel J., Nitsche A., Casas I., Caballero M.I., Zaballos A., Jimenez P., Jimenez M., Fernandez S.M., Fernandez S.V., de la Plaza I.C., Fadeev A., Ivanova A., Sergeeva M., Stefanelli P., Estee Torok M., Hall G., da Silva Filipe A., Turtle L., Afifi S., McCluggage K., Beer R., Ledesma J., Maksimovic J., Spellman K., Hamilton W.L., Marchbank A., Southgate J.A., Underwood A., Taylor B., Yeats C., Abudahab K., Gemmell M.R., Eccles R., Lucaci A., Nelson C.A., Rainbow L., Whitehead M., Gregory R., Haldenby S., Paterson S., Hughes M.A., Curran M.D., Baker D., Tucker R., Green L.R., Feltwell T., Halstead F.D., Wyles M., Jahun A.S., Ahmad S.S.Y., Georgana I., Goodfellow I., Yakovleva A., Meredith L.W., Gavriil A., Awan A.R., Fisher C., Edgeworth J., Lynch J., Moore N., Williams R., Kidd S.P., Cortes N., Brunker K., McCrone J.T., Quick J., Duckworth N., Walsh S., Sloan T., Ludden C., George R.P., Eltringham G., Brown J.R., Aranday-Cortes E., Shepherd J.G., Hughes J., Li K.K., Williams T.C., Johnson N., Jesudason N., Mair D., Thomson E., Shah R., Parr Y.A., Carmichael S., Robertson D.L., Nomikou K., Broos A., Niebel M., Smollett K., Tong L., Miah S., Wittner A., Phillips N., Payne B., Dewar R., Holmes A., Bolt F., Price J.R., Mookerjee S., Sethi D.K., Potter W., Stanley R., Prakash R., Dervisevic S., Graham J.C., Nelson A., Smith D., Young G.R., Yew W.C., Todd J.A., Trebes A., Andersson M., Bull M., Watkins J., Birchley A., Gatica-Wilcox B., Gilbert L., Kumziene-Summerhayes S., Rey S., Chauhan A., Butcher E., Bicknell K., Elliott S., Glaysher S., Lackenby A., Bibby D., Platt S., Mohamed H., Machin N.W., Mbisa J.L., Evans J., Perry M., Pacchiarini N., Corden S., Adams A.G., Gaskin A., Coombs J., Graham L.J., Cottrell S., Morgan M., Gifford L., Kolyva A., Rudder S.J., Trotter A.J., Mather A.E., Aydin A., Page A.J., Kay G.L., de Oliveira Martins L., Yasir M., Alikhan N.-F., Thomson N.M., Gilroy R., Kingsley R.A., O'Grady J., Gutierrez A.V., Diaz M., Viet T.L., Tedim A.P., Adriaenssens E.M., Patrick Mcclure C., Sang F., Clark G., Howson-Wells H.C., Debebe J., Ball J., Chappell J., Khakh M., Carlile M., Loose M., Lister M.M., Holmes N., Tsoleridis T., Fleming V.M., Wright V., Smith W., Gallagher M.D., Parker M., Partridge D.G., Evans C., Baker P., Essex S., Liggett S., Keeley A.J., Bashton M., Rooke S., Dervisavic S., Meader E.J., Lopez C.E.B., Angyal A., Kristiansen M., Tutill H.J., Findlay J., Mestek-Boukhibar L., Forrest L., Dyal P., Williams R.J., Panchbhaya Y., Williams C.A., Roy S., Pandey S., Stockton J., Loman N.J., Poplawski R., Nicholls S., Rowe W.P.M., Khokhar F., Pinckert M.L., Hosmillo M., Chaudhry Y., Caller L.G., Davidson R.K., Griffith L., Rambaut A., Jackson B., Colquhoun R., Hill V., Nichols J., Asamaphan P., Darby A., Jackson K.A., Iturriza-Gomara M., Vamos E.E., Green A., Aanensen D., Bonsall D., Buck D., Macintyre-Cockett G., de Cesare M., Pybus O., Golubchik T., Scarlett G., Loveson K.F., Robson S.C., Beckett A., Lindsey B., Groves D.C., Parsons P.J., McHugh M.P., Barnes J.D., Manso C.F., Grammatopoulos D., Menger K.E., Harrison E., Gunson R., Peacock S.J., Gonzalez G., Carr M., Mihaela L., Popovici O., Brytting M., Bresner C., Fuller W., Workman T., Mentis A.F., Kossyvakis A., Karamitros T., Pogka V., Kalliaropoulos A., Horefti E., Kontou A., Martinez-Gonzalez B., Labropoulou V., Voulgari-Kokota A., Evangelidou M., Bizta P., Belimezi M., Lambrechts L., Doymaz M.Z., Yazici M.K., Cetin N.S., Karaaslan E., Kallio-Kokko H., Virtanen J., Suvanto M., Nguyen P.T., Ellonen P., Hannula S., Kangas H., Sreenu V.B., Burian K., Terhes G., Gombos K., Gyenesei A., Urban P., Herczeg R., Jakab F., Kemenesi G., Toth G.E., Somogyi B., Zana B., Zeghbib S., Kuczmog A., Foldes F., Lanszki Z., Madai M., Papp H., Pereszlenyi C.I., Babinszky G.C., Dudas G., Csoma E., Abou Tayoun A.N., Alsheikh-Ali A.A., Loney T., Nowotny N., Abdul-Wahab O., Gonzalez-Candelas F., Andersen M.H., Taylor S., MARTI CARRERAS, Joan, Vanmechelen, Bert, Wawina, Tony, Medical Microbiology and Infection Prevention, AII - Infectious diseases, WHO European Region Sequencing Lab, GISAID EpiCoV Grp, Erik, Alm, Eeva K, Broberg, Thomas, Connor, Emma B, Hodcroft, Andrey B, Komissarov, Sebastian, Maurer-Stroh, Angeliki, Melidou, Richard A, Neher, Áine, O’Toole, Dmitriy, Pereyaslov, WHO European Region sequencing laboratories and GISAID EpiCoV group (Niko Beerenwinkel, The, Posada-Céspedes, Susana, Philipp, Kim, Jablonski, Falé Ferreira, Pedro, Topolsky, Ivan, Avšičžupanc, Tatjana, Korva, Miša, Poljak, Mario, Zakotnik, Samo, Tomaž, Zorec, Mark, Bragstad, Karoline, Hungnes, Olav, Stene-Johansen, Kathrine, Reusken, Chantal, Meijer, Adam, Vennema, Harry, Ruiz-Roldán, Lidia, Alma Bracho, María, García-González, Neri, Chiner-Oms, Álvaro, Cancino-Muñoz, Irving, Comas, Iñaki, A Goig, Galo, Torres-Puente, Manuela, G López, Mariana, Martínez-Priego, Llúcia, D’Auria, Giuseppe, LoretoFerrús-Abad, de Marco, Griselda, Galan-Vendrell, Inmaculada, Carbó-Ramirez, Sandra, Ruíz-Hueso, Paula, Coscollá, Mireia, Polackova, Katerina, Kramna, Lenka, Cinek, Ondrej, Richter, Jan, Krashias, George, Tryfonos, Christina, Bashiardes, Stavro, Koptides, Dana, Christodoulou, Christina, Bartolini, Barbara, Em Gruber, Cesare, Di Caro, Antonino, Castilletti, Concetta, Stefani, Fabrizio, Giordana Rimoldi, Sara, Romeri, Francesca, Salerno, Franco, Polesello, Stefano, Nagy, Alexander, Jirincova, Helena, Vecerova, Jaromira, Novakova, Ludmila, Cordey, Samuel, Murtskhvaladze, Marine, Kotaria, Nato, Schär, Tobia, Beisel, Christian, Vugrek, Oliver, Rokić, Filip, Trgovecgreif, Lovro, Jurak, Igor, Rukavina, Tomislav, Sučić, Neven, Schønning, Kristian, M Karst, Søren, H Kirkegaard, Rasmu, Y Michaelsen, Thoma, Aa Sørensen, Emil, Knutson, Simon, Brandt, Jakob, Le-Quy, Vang, Sørensen, Trine, Petersen, Celine, Schou Pedersen, Martin, Løkkegaard Larsen, Sanne, Nielsine Skov, Marianne, Rasmussen, Morten, Fonager, Jannik, Fomsgaard, Ander, Amirovich Maksyutov, Rinat, Vasil’Evna Gavrilova, Elena, Victorovich Pyankov, Oleg, Alexandrovich Bodnev, Sergey, Vladimirovna Tregubchak, Tatyana, Nikolayevich Shvalov, Alexander, Victorovich Antonets, Deni, Cristina Resende, Paola, Goya, Stephanie, Perrin, Amandine, Tc Lee, Raphael, Yadahalli, Shilpa, X Han, Alvin, A Russell, Colin, Schmutz, Stefan, Zaheri, Maryam, Kufner, Verena, Huber, Michael, Trkola, Alexandra, Antwerpen, Marku, C Walter, Mathia, van der Werf, Sylvie, Gambaro, Fabiana, Behillil, Sylvie, Enouf, Vincent, Donati, Flora, Ustinova, Monta, Rovite, Vita, Klovins, Jani, Savicka, Oksana, K Wienecke-Baldacchino, Anke, Ragimbeau, Catherine, Fournier, Guillaume, Mossong, Joël, W Aberle, Stephan, Haukland, Mattia, Enkirch, Theresa, Advani, Abdolreza, Lind Karlberg, Maria, Karlsson Lindsjö, Oskar, Broddesson, Sandra, Sláviková, Monika, Ličková, Martina, Klempa, Bori, Staroňová, Edita, Tichá, Elena, Szemes, Tomáš, Rusňáková, Diana, Stadler, Tanja, Quer, Josep, Anton, Andre, Andres, Cristina, Piñana, Maria, Garcia-Cehic, Damir, Pumarola, Toma, Izopet, Jacque, Gioula, Georgia, Exindari, Maria, Papa, Anna, Chatzidimitriou, Dimitrio, Metallidis, Symeon, Pappa, Stella, Macek Jr, Milan, Geryk, Jan, Brož, Petr, Briksí, Aleš, Hubáček, Petr, Dřevínek, Pavel, Zajac, Miroslav, Kvapil, Petr, Holub, Michal, Kvapilová, Kateřina, Novotný, Adam, Kašný, Martin, Klempt, Petr, Vapalahti, Olli, Smura, Teemu, Sironen, Tarja, Selhorst, Philippe, Anthony, Colin, Ariën, Kevin, Simon-Loriere, Etienne, Rabalski, Lukasz, Bienkowska-Szewczyk, Krystyna, Borges, Vítor, Isidro, Joana, Paulo Gomes, João, Guiomar, Raquel, Pechirra, Pedro, Costa, Inê, Duarte, Sílvia, Vieira, Luí, Pyrc, Krzysztof, S Zuckerman, Neta, Turdikulova, Shahlo, Abdullaev, Alisher, Dalimova, Dilbar, Abdurakhimov, Abror, Tagliabracci, Adriano, Alessandrini, Federica, Melchionda, Filomena, Onofri, Valerio, Turchi, Chiara, Bagnarelli, Patrizia, Menzo, Stefano, Caucci, Sara, Di Sante, Laura, Popa, Alexandra, Genger, Jakob-Wendelin, Agerer, Benedikt, Lercher, Alexander, Endler, Luka, Smyth, Mark, Penz, Thoma, Schuster, Michael, Senekowitsch, Martin, Laine, Jan, Bock, Christoph, Bergthaler, Andrea, Shevtsov, Alexandr, Kalendar, Ruslan, Ramanculov, Yerlan, Graf, Alexander, Muenchhoff, Maximilian, T Keppler, Oliver, Krebs, Stefan, Blum, Helmut, Marcello, Alessandro, Licastro, Danilo, D’Agaro, Pierlanfranco, Laubscher, Florian, Vidanovic, Dejan, Tesovic, Bojana, Volkening, Jeremy, Clementi, Nicola, Mancini, Nicasio, Rupnik, Maja, Mahnic, Aleksander, Walker, Andrea, Houwaart, Torsten, Wienemann, Tobia, Kohns Vasconcelos, Malte, Strelow, Daniel, Ole Jensen, Björn-Erik, Senff, Tina, Hülse, Lisanna, Adams, Ortwin, Andree, Marcel, Hauka, Sandra, Feldt, Torsten, Keitel, Verena, Kindgen-Milles, Detlef, Timm, Jörg, Pfeffer, Klau, T Dilthey, Alexander, Moore, Catherine, Ozdarendeli, Aykut, Terkis Islam Pavel, Shaikh, Yetiskin, Hazel, Aydin, Gunsu, Holyavkin, Can, Ali Uygut, Muhammet, Cevik, Ceren, Shchetinin, Alexey, Gushchin, Vladimir, Dinler-Doganay, Gizem, Doganay, Levent, Kizilboga-Akgun, Tugba, Karacan, Ilker, Pancer, Katarzyna, Maes, Piet, Martí-Carreras, Joan, Wawina-Bokalanga, Tony, Thürmer, Andrea, Wedde, Marianne, Dürrwald, Ralf, Von Kleist, Max, Drechsel, Oliver, Wolff, Thorsten, Fuchs, Stephan, Kmiecinski, Rene, Michel, Janine, Nitsche, Andrea, Casas, Inmaculada, Iglesias Caballero, María, Zaballos, Ángel, Jiménez, Pilar, Jiménez, Mercede, Monzón Fernández, Sara, Varona Fernández, Sarai, Cuesta De La Plaza, Isabel, Fadeev, Artem, Ivanova, Anna, Sergeeva, Mariia, Stefanelli, Paola, Estee Torok, M, Hall, Grant, da Silva Filipe, Ana, Turtle, Lance, Afifi, Safiah, Mccluggage, Kathryn, Beer, Robert, Ledesma, Juan, Maksimovic, Joshua, Spellman, Karla, L Hamilton, William, Marchbank, Angela, Alexander Southgate, Joel, Underwood, Anthony, Taylor, Ben, Yeats, Corin, Abudahab, Khalil, R Gemmell, Matthew, Eccles, Richard, Lucaci, Anita, Abigail Nelson, Charlotte, Rainbow, Lucille, Whitehead, Mark, Gregory, Richard, Haldenby, Sam, Paterson, Steve, A Hughes, Margaret, D Curran, Martin, Baker, David, Tucker, Rachel, R Green, Luke, Feltwell, Theresa, D Halstead, Fenella, Wyles, Matthew, S Jahun, Aminu, Y Ahmad, Shazaad S, Georgana, Iliana, Goodfellow, Ian, Yakovleva, Anna, W Meredith, Luke, Gavriil, Artemi, Raza Awan, Ali, Fisher, Chloe, Jonathan, European Centre for Disease Prevention and Control [Stockholm, Sweden] (ECDC), Cardiff University, Public Health Wales [Cardiff, Royaume uni], University of Basel (Unibas), Research Institute of Influenza, St. Petersburg, Russia, Agency for science, technology and research [Singapore] (A*STAR), National University of Singapore (NUS), University of Edinburgh, WHO Regional Office for Europe [Copenhagen], We gratefully acknowledge the authors, originating and submitting laboratories of the sequences from GISAID’s EpiCoV Database used in the phylogenetic analysis. We gratefully acknowledge all the staff working with sample collection, sample preparation, sequencing, data analysis and data sharing in all laboratories in the WHO European Region for making this work possible, The WHO European Region sequencing laboratories and GISAID EpiCoV group*: Niko Beerenwinkel, Susana Posada-Céspedes, Kim Philipp Jablonski, Pedro Falé Ferreira, Ivan Topolsky, Tatjana Avšič-Županc, Miša Korva, Mario Poljak, Samo Zakotnik, Tomaž Mark Zorec, Karoline Bragstad, Olav Hungnes, Kathrine Stene-Johansen, Chantal Reusken, Adam Meijer, Harry Vennema, Lidia Ruiz-Roldán, María Alma Bracho, Neris García-González, Álvaro Chiner-Oms, Irving Cancino-Muñoz, Iñaki Comas, Galo A Goig, Manuela Torres-Puente, Mariana G López, Llúcia Martínez-Priego, Giuseppe D'Auria, Paula Ruíz-Hueso, Loreto Ferrús-Abad, Griselda de Marco, Inmaculada Galan-Vendrell, Sandra Carbó-Ramirez, Paula Ruiz-Rodriguez, Mireia Coscollá, Katerina Polackova, Lenka Kramna, Ondrej Cinek, Jan Richter, George Krashias, Christina Tryfonos, Stavros Bashiardes, Dana Koptides, Christina Christodoulou, Barbara Bartolini, Cesare Em Gruber, Antonino Di Caro, Concetta Castilletti, Fabrizio Stefani, Sara Giordana Rimoldi, Francesca Romeri, Franco Salerno, Stefano Polesello, Alexander Nagy, Helena Jirincova, Jaromira Vecerova, Ludmila Novakova, Samuel Cordey, Marine Murtskhvaladze, Nato Kotaria, Tobias Schär, Christian Beisel, Oliver Vugrek, Filip Rokić, Lovro Trgovec-Greif, Igor Jurak, Tomislav Rukavina, Neven Sučić, Kristian Schønning, Søren M Karst, Rasmus H Kirkegaard, Thomas Y Michaelsen, Emil Aa Sørensen, Simon Knutson, Jakob Brandt, Vang Le-Quy, Trine Sørensen, Celine Petersen, Martin Schou Pedersen, Sanne Løkkegaard Larsen, Marianne Nielsine Skov, Morten Rasmussen, Jannik Fonager, Anders Fomsgaard, Rinat Amirovich Maksyutov, Elena Vasil'Evna Gavrilova, Oleg Victorovich Pyankov, Sergey Alexandrovich Bodnev, Tatyana Vladimirovna Tregubchak, Alexander Nikolayevich Shvalov, Denis Victorovich Antonets, Paola Cristina Resende, Stephanie Goya, Amandine Perrin, Raphael Tc Lee, Shilpa Yadahalli, Alvin X Han, Colin A Russell, Stefan Schmutz, Maryam Zaheri, Verena Kufner, Michael Huber, Alexandra Trkola, Markus Antwerpen, Mathias C Walter, Sylvie van der Werf, Fabiana Gambaro, Sylvie Behillil, Vincent Enouf, Flora Donati, Monta Ustinova, Vita Rovite, Janis Klovins, Oksana Savicka, Anke K Wienecke-Baldacchino, Catherine Ragimbeau, Guillaume Fournier, Joël Mossong, Stephan W Aberle, Mattias Haukland, Theresa Enkirch, Abdolreza Advani, Maria Lind Karlberg, Oskar Karlsson Lindsjö, Sandra Broddesson, Monika Sláviková, Martina Ličková, Boris Klempa, Edita Staroňová, Elena Tichá, Tomáš Szemes, Diana Rusňáková, Tanja Stadler, Josep Quer, Andres Anton, Cristina Andres, Maria Piñana, Damir Garcia-Cehic, Tomas Pumarola, Jacques Izopet, Georgia Gioula, Maria Exindari, Anna Papa, Dimitrios Chatzidimitriou, Symeon Metallidis, Stella Pappa, Milan Macek Jr, Jan Geryk, Petr Brož, Aleš Briksí, Petr Hubáček, Pavel Dřevínek, Miroslav Zajac, Petr Kvapil, Michal Holub, Kateřina Kvapilová, Adam Novotný, Martin Kašný, Petr Klempt, Olli Vapalahti, Teemu Smura, Tarja Sironen, Philippe Selhorst, Colin Anthony, Kevin Ariën, Etienne Simon-Loriere, Lukasz Rabalski, Krystyna Bienkowska-Szewczyk, Vítor Borges, Joana Isidro, João Paulo Gomes, Raquel Guiomar, Pedro Pechirra, Inês Costa, Sílvia Duarte, Luís Vieira, Krzysztof Pyrc, Neta S Zuckerman, Shahlo Turdikulova, Alisher Abdullaev, Dilbar Dalimova, Abror Abdurakhimov, Adriano Tagliabracci, Federica Alessandrini, Filomena Melchionda, Valerio Onofri, Chiara Turchi, Patrizia Bagnarelli, Stefano Menzo, Sara Caucci, Laura Di Sante, Alexandra Popa, Jakob-Wendelin Genger, Benedikt Agerer, Alexander Lercher, Lukas Endler, Mark Smyth, Thomas Penz, Michael Schuster, Martin Senekowitsch, Jan Laine, Christoph Bock, Andreas Bergthaler, Alexandr Shevtsov, Ruslan Kalendar, Yerlan Ramanculov, Alexander Graf, Maximilian Muenchhoff, Oliver T Keppler, Stefan Krebs, Helmut Blum, Alessandro Marcello, Danilo Licastro, Pierlanfranco D'Agaro, Florian Laubscher, Dejan Vidanovic, Bojana Tesovic, Jeremy Volkening, Nicola Clementi, Nicasio Mancini, Maja Rupnik, Aleksander Mahnic, Andreas Walker, Torsten Houwaart, Tobias Wienemann, Malte Kohns Vasconcelos, Daniel Strelow, Björn-Erik Ole Jensen, Tina Senff, Lisanna Hülse, Ortwin Adams, Marcel Andree, Sandra Hauka, Torsten Feldt, Verena Keitel, Detlef Kindgen-Milles, Jörg Timm, Klaus Pfeffer, Alexander T Dilthey, Catherine Moore, Aykut Ozdarendeli, Shaikh Terkis Islam Pavel, Hazel Yetiskin, Gunsu Aydin, Can Holyavkin, Muhammet Ali Uygut, Ceren Cevik, Alexey Shchetinin, Vladimir Gushchin, Gizem Dinler-Doganay, Levent Doganay, Tugba Kizilboga-Akgun, Ilker Karacan, Katarzyna Pancer, Piet Maes, Joan Martí-Carreras, Tony Wawina-Bokalanga, Bert Vanmechelen, Andrea Thürmer, Marianne Wedde, Ralf Dürrwald, Max Von Kleist, Oliver Drechsel, Thorsten Wolff, Stephan Fuchs, Rene Kmiecinski, Janine Michel, Andreas Nitsche, Inmaculada Casas, María Iglesias Caballero, Ángel Zaballos, Pilar Jiménez, Mercedes Jiménez, Sara Monzón Fernández, Sarai Varona Fernández, Isabel Cuesta De La Plaza, Artem Fadeev, Anna Ivanova, Mariia Sergeeva, Paola Stefanelli, M Estee Torok, Grant Hall, Ana da Silva Filipe, Lance Turtle, Safiah Afifi, Kathryn Mccluggage, Robert Beer, Juan Ledesma, Joshua Maksimovic, Karla Spellman, William L Hamilton, Angela Marchbank, Joel Alexander Southgate, Anthony Underwood, Ben Taylor, Corin Yeats, Khalil Abudahab, Matthew R Gemmell, Richard Eccles, Anita Lucaci, Charlotte Abigail Nelson, Lucille Rainbow, Mark Whitehead, Richard Gregory, Sam Haldenby, Steve Paterson, Margaret A Hughes, Martin D Curran, David Baker, Rachel Tucker, Luke R Green, Theresa Feltwell, Fenella D Halstead, Matthew Wyles, Aminu S Jahun, Shazaad S Y Ahmad, Iliana Georgana, Ian Goodfellow, Anna Yakovleva, Luke W Meredith, Artemis Gavriil, Ali Raza Awan, Chloe Fisher, Jonathan Edgeworth, Jessica Lynch, Nathan Moore, Rebecca Williams, Stephen P Kidd, Nicholas Cortes, Kirstyn Brunker, John T Mccrone, Joshua Quick, Nichola Duckworth, Sarah Walsh, Tim Sloan, Catherine Ludden, Ryan P George, Gary Eltringham, Julianne R Brown, Elihu Aranday-Cortes, James G Shepherd, Joseph Hughes, Kathy K Li, Thomas C Williams, Natasha Johnson, Natasha Jesudason, Daniel Mair, Emma Thomson, Rajiv Shah, Yasmin A Parr, Stephen Carmichael, David L Robertson, Kyriaki Nomikou, Alice Broos, Marc Niebel, Katherine Smollett, Lily Tong, Shahjahan Miah, Anita Wittner, Nicole Phillips, Brendan Payne, Rebecca Dewar, Alison Holmes, Frances Bolt, James R Price, Siddharth Mookerjee, Dheeraj K Sethi, Will Potter, Rachael Stanley, Reenesh Prakash, Samir Dervisevic, Jonathan Clive Graham, Andrew Nelson, Darren Smith, Gregory R Young, Wen Chyin Yew, John A Todd, Amy Trebes, Monique Andersson, Matthew Bull, Joanne Watkins, Alec Birchley, Bree Gatica-Wilcox, Lauren Gilbert, Sara Kumžiene-Summerhayes, Sara Rey, Anoop Chauhan, Ethan Butcher, Kelly Bicknell, Scott Elliott, Sharon Glaysher, Angie Lackenby, David Bibby, Steven Platt, Hodan Mohamed, Nicholas William Machin, Jean Lutamyo Mbisa, Jonathan Evans, Malorie Perry, Nicole Pacchiarini, Sally Corden, Alexander Geraint Adams, Amy Gaskin, Jason Coombs, Lee John Graham, Simon Cottrell, Mari Morgan, Laura Gifford, Anastasia Kolyva, Steven John Rudder, Alexander J Trotter, Alison E Mather, Alp Aydin, Andrew J Page, Gemma L Kay, Leonardo de Oliveira Martins, Muhammad Yasir, Nabil-Fareed Alikhan, Nicholas M Thomson, Rachel Gilroy, Robert A Kingsley, Justin O'Grady, Ana Victoria Gutierrez, Maria Diaz, Thanh Le Viet, Ana P Tedim, Evelien M Adriaenssens, C Patrick Mcclure, Christopher Moore, Fei Sang, Gemma Clark, Hannah C Howson-Wells, Johnny Debebe, Jonathan Ball, Joseph Chappell, Manjinder Khakh, Matthew Carlile, Matthew Loose, Michelle M Lister, Nadine Holmes, Theocharis Tsoleridis, Vicki M Fleming, Victoria Wright, Wendy Smith, Michael D Gallagher, Matthew Parker, David G Partridge, Cariad Evans, Paul Baker, Sarah Essex, Steven Liggett, Alexander J Keeley, Matthew Bashton, Stefan Rooke, Samir Dervisevic, Emma Jane Meader, Carlos Enrique Balcazar Lopez, Adrienn Angyal, Mark Kristiansen, Helena J Tutill, Jacqueline Findlay, Lamia Mestek-Boukhibar, Leysa Forrest, Patricia Dyal, Rachel J Williams, Yasmin Panchbhaya, Charlotte A Williams, Sunando Roy, Sarojini Pandey, Jo Stockton, Nicholas J Loman, Radoslaw Poplawski, Samuel Nicholls, W P M Rowe, Fahad Khokhar, Malte Lars Pinckert, Myra Hosmillo, Yasmin Chaudhry, Laura G Caller, Rose K Davidson, Luke Griffith, Andrew Rambaut, Ben Jackson, Rachel Colquhoun, Verity Hill, Jenna Nichols, Patawee Asamaphan, Alistair Darby, Kathryn A Jackson, Miren Iturriza-Gomara, Ecaterina Edith Vamos, Angie Green, David Aanensen, David Bonsall, David Buck, George Macintyre-Cockett, Mariateresa de Cesare, Oliver Pybus, Tanya Golubchik, Garry Scarlett, Katie F Loveson, Samuel C Robson, Angela Beckett, Benjamin 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A., Trebes, A., Andersson, M., Bull, M., Watkins, J., Birchley, A., Gatica-Wilcox, B., Gilbert, L., Kumziene-Summerhayes, S., Rey, S., Chauhan, A., Butcher, E., Bicknell, K., Elliott, S., Glaysher, S., Lackenby, A., Bibby, D., Platt, S., Mohamed, H., Machin, N. W., Mbisa, J. L., Evans, J., Perry, M., Pacchiarini, N., Corden, S., Adams, A. G., Gaskin, A., Coombs, J., Graham, L. J., Cottrell, S., Morgan, M., Gifford, L., Kolyva, A., Rudder, S. J., Trotter, A. J., Mather, A. E., Aydin, A., Page, A. J., Kay, G. L., de Oliveira Martins, L., Yasir, M., Alikhan, N. -F., Thomson, N. M., Gilroy, R., Kingsley, R. A., O'Grady, J., Gutierrez, A. V., Diaz, M., Viet, T. L., Tedim, A. P., Adriaenssens, E. M., Patrick Mcclure, C., Sang, F., Clark, G., Howson-Wells, H. C., Debebe, J., Ball, J., Chappell, J., Khakh, M., Carlile, M., Loose, M., Lister, M. M., Holmes, N., Tsoleridis, T., Fleming, V. M., Wright, V., Smith, W., Gallagher, M. D., Parker, M., Partridge, D. 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H., Taylor, S., European Centre for Disease Prevention and Control (ECDC), Public Health Wales Microbiology Cardiff, Faculty of Agriculture and Forestry, Department of Agricultural Sciences, and Institute of Biotechnology
Subjects: Infecções Respiratórias, 0301 basic medicine, MESH: Coronavirus Infections, Epidemiology, [SDV]Life Sciences [q-bio], Distribution (economics), Wastewater, MESH: Base Sequence, Severe Acute Respiratory Syndrome, MESH: World Health Organization, Pandemic, MESH: Coronavirus, MESH: COVID-19, Sequencing, Viral, Clade, Nomenclature, Genome, biology, COVID-19, Europe, NGS, SARS-CoV-2, WGS, nomenclature, sequencing, Base Sequence, Betacoronavirus, Coronavirus, Coronavirus Infections, Genome, Viral, Humans, Phylogeography, Pneumonia, Viral, RNA, Viral, RNA-Dependent RNA Polymerase, Spatio-Temporal Analysis, World Health Organization, Pandemics, C500, European region, 3. Good health, Geography, MESH: Phylogeography, MESH: RNA-Dependent RNA Polymerase, MESH: RNA, Viral, MESH: Betacoronavirus, Spatio-Temporal Analysi, MESH: Genome, Viral, Cartography, Human, Bioquímica, MESH: Pandemics, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronaviru, 030106 microbiology, 03 medical and health sciences, MESH: Spatio-Temporal Analysis, MESH: Severe Acute Respiratory Syndrome, Virology, MESH: SARS-CoV-2, Whole genome sequencing, MESH: Humans, Whole Genome Sequencing, Betacoronaviru, Coronavirus Infection, business.industry, Public Health, Environmental and Occupational Health, Pneumonia, biology.organism_classification, B900, 030104 developmental biology, MESH: Pneumonia, Viral, RNA, SARS_CoV-2, 3111 Biomedicine, MESH: Europe, Human medicine, business
Abstract: 8 páginas, 3 figuras, We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the World Health Organization European Region available until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation, compare the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2., We gratefully acknowledge the authors, originating and submitting laboratories of the sequences from GISAID’s EpiCoV Database used in the phylogenetic analysis. We gratefully acknowledge all the staff working with sample collection, sample preparation, sequencing, data analysis and data sharing in all laboratories in the WHO European Region for making this work possible.
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47. Tuberculosis Disease in Immunocompromised Children and Adolescents: A Pediatric Tuberculosis Network European Trials Group Multicenter Case-control Study.

Author: Rodríguez-Molino P, Tebruegge M, Noguera-Julian A, Neth O, Fidler K, Brinkmann F, Sainz T, Ivaskeviciene I, Ritz N, Brito MJ, Milheiro Silva T, Chechenieva V, Serdiuk M, Lancella L, Russo C, Soler-García A, Navarro ML, Krueger R, Feiterna-Sperling C, Starshinova A, Hiteva A, Hoffmann A, Kalibatas P, Lo Vecchio A, Scarano SM, Bustillo M, Blázquez Gamero D, Espiau M, Buonsenso D, Falcón L, Turnbull L, Colino E, Rueda S, Buxbaum C, Carazo B, Alvarez C, Dapena M, Piqueras A, Velizarova S, Ozere I, Götzinger F, Pareja M, Garrote Llanos MI, Soto B, Rodríguez Martín S, Korta JJ, Pérez-Gorricho B, Herranz M, Hernández-Bartolomé Á, Díaz-Almirón M, Kohns Vasconcelos M, Ferreras-Antolín L, and Santiago-García B
Subjects: Humans, Case-Control Studies, Child, Male, Female, Adolescent, Europe epidemiology, Child, Preschool, Infant, Tuberculin Test, Antitubercular Agents therapeutic use, Immunocompromised Host, Tuberculosis epidemiology, Tuberculosis diagnosis
Abstract: Background: In high-resource settings, the survival of children with immunocompromise (IC) has increased and immunosuppressive therapies are increasingly being used. This study aimed to determine the clinical characteristics, performance of diagnostic tools, and outcome of IC children with tuberculosis (TB) in Europe., Methods: Multicenter, matched case-control study within the Pediatric Tuberculosis Network European Trials Group, capturing TB cases <18 years diagnosed 2000-2020., Results: A total of 417 TB cases were included, comprising 139 children who are IC (human immunodeficiency virus, inborn errors of immunity, drug-induced immunosuppression, and other immunocompromising conditions) and 278 non-IC children as controls. Nonrespiratory TB was more frequent among cases than controls (32.4% vs 21.2%; P = .013). Patients with IC had an increased likelihood of presenting with severe disease (57.6% vs 38.5%; P < .001; odds ratio [95% confidence interval], 2.073 [1.37-3.13]). Children with IC had higher rates of false-negative tuberculin skin test (31.9% vs 6.0%; P < .001) and QuantiFERON-TB Gold assay (30.0% vs 7.3%; P < .001) results at diagnosis. Overall, the microbiological confirmation rate was similar in IC and non-IC cases (58.3% vs 49.3%; P = .083). Although the mortality in children with IC was <1%, the rate of long-term sequelae was significantly higher than in non-IC cases (14.8% vs 6.1%; P = .004)., Conclusions: Children with IC and TB in Europe have increased rates of nonrespiratory TB, severe disease, and long-term sequelae. Immune-based TB tests have poor sensitivity in those children. Future research should focus on developing improved immunological TB tests that perform better in patients with IC, and determining the reasons for the increased risk of long-term sequelae, with the aim to design preventive management strategies., Competing Interests: Potential conflicts of interest . B. S. G. and M. T. have received support from Cepheid for a project on molecular tuberculosis diagnostics unrelated to the study reported here. M. T. has received QuantiFERON-TB assays at reduced pricing or free of charge for tuberculosis diagnostics projects from Cellestis/Qiagen in the past and has received support for conference attendance from Cepheid. The manufacturers had no influence on the study design, data collection, analysis or interpretation, writing of the manuscript, or the decision to submit the data for publication. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed., (© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Published: 2024
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48. Diphtheria in a Swiss Asylum Seeker Reception Centre: Outbreak Investigation and Evaluation of Testing and Vaccination Strategies.

Author: Brockhaus L, Urwyler P, Leutwyler U, Würfel E, Kohns Vasconcelos M, Goldenberger D, Keller PM, Tschudin Sutter S, and Labhardt ND
Subjects: Humans, Switzerland, Retrospective Studies, Male, Female, Adult, Adolescent, Young Adult, Vaccination statistics & numerical data, Corynebacterium diphtheriae, Middle Aged, Mass Screening, Refugees statistics & numerical data, Diphtheria prevention & control, Diphtheria epidemiology, Disease Outbreaks prevention & control
Abstract: Objectives: To describe a suspected diphtheria outbreak in a Swiss asylum seeker reception centre, and to analyse its management response regarding testing and vaccination. Methods: We retrospectively analysed clinical, microbiology, and case management data of all asylum seekers tested for C. diphtheriae between 28th August and 31st December 2022 while residing at the centre. Results are reported descriptively. Results: Among 265 individuals tested, ten cases of cutaneous diphtheria, one simultaneous respiratory and cutaneous case, and nine respiratory carriers were identified. Mass throat screening, targeted throat testing and targeted wound testing yielded 4.8%, 4.3%, and 17.4% positive results, respectively. No respiratory carrier was identified among cutaneous cases undergoing a throat swab, and no symptomatic case was identified among individuals with unspecific throat symptoms. Rates of vaccination implementation of newly arriving asylum seekers before and after the outbreak were low (17.5% and 15.5%, respectively), as were rates of targeted vaccination among cases and close contacts. Conclusion: We provide evidence for transmission both prior to arrival and within the setting, suboptimal practices and timeliness of testing, and implementation gaps in vaccination., Competing Interests: The authors declare that they do not have any conflicts of interest., (Copyright © 2024 Brockhaus, Urwyler, Leutwyler, Würfel, Kohns Vasconcelos, Goldenberger, Keller, Tschudin Sutter and Labhardt.)
Published: 2024
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49. Detection of mostly viral pathogens and high proportion of antibiotic treatment initiation in hospitalised children with community-acquired pneumonia in Switzerland - baseline findings from the first two years of the KIDS-STEP trial.

Author: Kohns Vasconcelos M, Meyer Sauteur PM, Keitel K, Santoro R, Egli A, Coslovsky M, Seiler M, Lurà M, Köhler H, Loevy N, Kahlert CR, Heininger U, Van den Anker J, and Bielicki JA
Subjects: Child, Humans, Child, Preschool, Child, Hospitalized, Switzerland, Hospitalization, COVID-19, Pneumonia, Community-Acquired Infections drug therapy
Abstract: Aims of the Study: Globally, since the introduction of conjugate-vaccines against encapsulated bacteria, respiratory viruses have caused most hospitalisations for community-acquired pneumonia. The aim of this study was to describe pathogens detected and their association with clinical findings in Switzerland., Methods: Baseline data were analysed for all trial participants enrolled between September 2018 and September 2020 into the KIDS-STEP Trial, a randomised controlled superiority trial on the effect of betamethasone on clinical stabilisation of children admitted with community-acquired pneumonia. Data included clinical presentation, antibiotic use and results of pathogen detection. In addition to routine sampling, nasopharyngeal specimens were analysed for respiratory pathogens using a panel polymerase chain reaction test covering 18 viral and 4 bacterial pathogens., Results: 138 children with a median age of 3 years were enrolled at the eight trial sites. Fever (obligatory for enrolment) had been present for median 5 days before admission. Most common symptoms were reduced activity (129, 93.5%) and reduced oral intake (108, 78.3%). Oxygen saturation <92% was found in 43 (31.2%). Forty-three participants (29.0%) were already on antibiotic treatment prior to admission and 104 participants (75.4%) received antibiotic treatment on admission. Pathogen testing results were available from 132 children: 31 (23.5%) had respiratory syncytial virus detected, 21 (15.9%) human metapneumovirus. The pathogens detected showed expected seasonal and age preponderance and were not associated with chest X-ray findings., Conclusions: In the context of the predominantly viral pathogens detected, the majority of antibiotic treatment is probably unnecessary. The ongoing trial, as well as other studies, will be able to provide comparative pathogen detection data to compare pre- and post-COVID-19-pandemic settings.
Published: 2023
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50. Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.

Author: Houwaart T, Belhaj S, Tawalbeh E, Nagels D, Fröhlich Y, Finzer P, Ciruela P, Sabrià A, Herrero M, Andrés C, Antón A, Benmoumene A, Asskali D, Haidar H, von Dahlen J, Nicolai J, Stiller M, Blum J, Lange C, Adelmann C, Schroer B, Osmers U, Grice C, Kirfel PP, Jomaa H, Strelow D, Hülse L, Pigulla M, Kreuzer P, Tyshaieva A, Weber J, Wienemann T, Kohns Vasconcelos M, Hoffmann K, Lübke N, Hauka S, Andree M, Scholz CJ, Jazmati N, Göbels K, Zotz R, Pfeffer K, Timm J, Ehlkes L, Walker A, and Dilthey AT
Subjects: Humans, SARS-CoV-2 genetics, Travel, Phylogeny, Contact Tracing, Germany epidemiology, Genomics, Communicable Diseases, Imported epidemiology, COVID-19 epidemiology
Abstract: BackgroundTracking person-to-person SARS-CoV-2 transmission in the population is important to understand the epidemiology of community transmission and may contribute to the containment of SARS-CoV-2. Neither contact tracing nor genomic surveillance alone, however, are typically sufficient to achieve this objective.AimWe demonstrate the successful application of the integrated genomic surveillance (IGS) system of the German city of Düsseldorf for tracing SARS-CoV-2 transmission chains in the population as well as detecting and investigating travel-associated SARS-CoV-2 infection clusters.MethodsGenomic surveillance, phylogenetic analysis, and structured case interviews were integrated to elucidate two genetically defined clusters of SARS-CoV-2 isolates detected by IGS in Düsseldorf in July 2021.ResultsCluster 1 (n = 67 Düsseldorf cases) and Cluster 2 (n = 36) were detected in a surveillance dataset of 518 high-quality SARS-CoV-2 genomes from Düsseldorf (53% of total cases, sampled mid-June to July 2021). Cluster 1 could be traced back to a complex pattern of transmission in nightlife venues following a putative importation by a SARS-CoV-2-infected return traveller (IP) in late June; 28 SARS-CoV-2 cases could be epidemiologically directly linked to IP. Supported by viral genome data from Spain, Cluster 2 was shown to represent multiple independent introduction events of a viral strain circulating in Catalonia and other European countries, followed by diffuse community transmission in Düsseldorf.ConclusionIGS enabled high-resolution tracing of SARS-CoV-2 transmission in an internationally connected city during community transmission and provided infection chain-level evidence of the downstream propagation of travel-imported SARS-CoV-2 cases.
Published: 2022
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