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7 results on '"Lorente, Inmaculada"'

1. MicroRNAs as New Regulators of Neutrophil Extracellular Trap Formation

Author

Águila, Sonia, primary, de los Reyes-García, Ascensión M., additional, Fernández-Pérez, María P., additional, Reguilón-Gallego, Laura, additional, Zapata-Martínez, Laura, additional, Ruiz-Lorente, Inmaculada, additional, Vicente, Vicente, additional, González-Conejero, Rocío, additional, and Martínez, Constantino, additional

Published
2021
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2. Usos del PEEK en prótesis dental

Author

Partal Lorente, Inmaculada, Arroyo Cruz, Gema, and Universidad de Sevilla. Departamento de Estomatología

Subjects
PEEK, Prótesis dentales
Abstract

Objetivo: Determinar la evidencia científica existente en relación al uso actual del PEEK como nuevo material en Prótesis Dental así como las ventajas e inconvenientes que se le atribuyen en dichos usos. Material y método: Se realiza una revisión bibliográfica, con búsquedas electrónicas en PubMed y Scopus, con el fin de identificar aquellos trabajos en los que se empleara el Peek en algún tipo de Prótesis Dental. Resultados: Con la estrategia de búsqueda empleada encontramos un total de 283 artículos en PubMed y más de 4000 en Scopus. Finalmente seleccionamos 26 artículos para realizar este trabajo que era los que cumplían los criterios considerados. Conclusiones: Aunque actualmente se está empleando el Peek para la fabricación de distintos tipos de prótesis dentales (prótesis parciales removibles, prótesis fijas de hasta 3 piezas, obturadores palatinos, retenciones para sobredenturas, estructuras de prótesis implantosoportadas, provisionales y tornillos de implantes) se carece de un número suficiente de estudios y de un seguimiento en el tiempo que lo abalen y por tanto aun no estamos en disposición de recomendar la sustitución de los materiales tradicionales por estos de nueva aparición. Purpose: Determine the existing scientific evidence regarding the material of the actual use of PEEK for dental use and the advantages and disadvantages that are attributed in prosthesis. Materials and method: A literature review was performed, with electronic searches of PubMed and Scopus , in order to identify those jobs where the Peek is employed in some type of dental prosthesis. Results: The search strategy employed found a total of 283 articles in PubMed and 4000 in Scopus. Finally we selected 26 items for this work those which met with the criteria considered. Conclusions: Although currently being used the Peek for the manufacture of various types of dentures ( removable partial dentures , fixed prostheses up to 3 pieces, shutters palatine , retentions sobredenturas , structures implant prostheses, provisional and screw implants ) is lacking a sufficient number of studies and monitoring over time that abalen and therefore we are not yet ready to recommend the replacement of traditional materials by these new appearance. Universidad de Sevilla. Grado en Odontología

Published
2016

7. HLA-C*07 is associated with symptomatic HIV-1-associated neurocognitive disorders (HAND) and immune dysregulation.

Author

Pons-Fuster, Eduardo, Bernal, Enrique, Guillamón, Concepción F., Gimeno, Lourdes, Martínez-Sánchez, María V., Ruiz-Lorente, Inmaculada, Campillo, José A., Ceballos, Diana, Torres, Ana, Tomás, Cristina, Muñoz, Ángeles, Alcaraz, Antonia, Selma, Pedro, Ruiz-Nicolas, Carlos, Muro, Manuel, and Minguela, Alfredo

Abstract

AbstractBackgroundObjectiveMethodsResultsConclusionHIV-1-associated neurocognitive disorders (HAND) in stable patients undergoing antiretroviral therapy (ART) may result from ongoing immune dysregulation and chronic inflammation. A contributing factor may result from the unstable HLA class I allele, HLA-C*07.To assess the genetic profile of killer-cell immunoglobulin-like receptors (KIR), human leukocyte antigens (HLA), and immune activation or senescence markers and their association with HAND in stable HIV-1 patients receiving ART.An observational cross-sectional study was carried out with 96 patients with asymptomatic or symptomatic HAND. HLA and KIR as well as immune activation/senescence biomarkers in peripheral blood cells were assessed by SSO-Luminex typing and flow cytometry, respectively.HLA-C*07 is associated with symptomatic HAND. The frequency of two copies of HLA-C*07 was higher in patients with symptomatic than with asymptomatic HAND (12.0 vs. 2.2%, ρ < 0.001). The percentage of senescent CD8+CD28- T-cells was higher in patients with two copies of HLA-C*07 (ρ < 0.05). In patients with symptomatic HAND, the percentages of non-senescent CD8+CD28+ T cells were inversely proportional to the number of copies of the HLA-C*07 (ρ < 0.05).Patients with symptomatic HAND showed a higher frequency of the homozygotic unstable HLA-C*07 allotype, which could be associated with neurocognitive complications. Two copies of HLA-C*07 were associated with immune senescent T lymphocyte profiles characterized by the loss of CD28 expression. [ABSTRACT FROM AUTHOR]

Published
2024
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