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The article describes the associative infection of sheep with parasitic diseases. Determining the presence of helminthic and blood-parasitic diseases was carried out in sheep farms of the Masalli region of Azerbaijan. In scatological studies in animals, infection with nematodiasis caused by the nematode Nematodirus spathiger from the Trichostrongylidae family was detected, and a clinical examination of sick and recovered sheep was also carried out. Anaplasmosis and babesiosis have been registered in sheep, the carriers of which are ticks Rhipisephalus bursa. Microscopic examination of the causative agent of anaplasmosis and babesiosis is located in the center of erythrocytes, and up to 1-4 parasites can be traced in one erythrocyte. The parasites are round and pear-shaped, 1.2-5 µm in size with a pear-shaped form and 1-1.5 µm with a round one, and there are about 20-45% of babesias in 100 fields of view of a microscope. Thus, an association of parasitic diseases - nematodirosis, babesiosis and anaplasmosis has been established in the sheep farms of the Masalli region of Azerbaijan.

Honey production in our country has increased compared to the last decade. East Kazakhstan, Almaty and South Kazakhstan regions are the main producers of honey. The floral diversity of our country makes it possible to obtain many types of monofloral honey and several combinations of polyfloral honey. Floral origin is one of the most important factors influencing the honey market. Monofloral honey is more popular among consumers due to its taste, special characteristics and is more profitable for producers due to its high price. Darker honey (buckwheat honey) usually contains high amounts of antioxidants, which increase its health potential. Food control is a major factor for consumers who want to know that their purchases are of high quality. To ensure that the actual composition of the products indicated on the label, analysis and development of effective methods of analysis is necessary. Therefore, the aim of this study is to identify biomarkers of buckwheat honey by vacuum solid phase microextraction (vac-SPME) in combination with gas chromatography-mass spectrometry (GC-MS).

Joint conversion of the propane–butane fraction of gaseous С3–С4 alkanes and straight-run naphtha by involving them in the joint isomerization–disproportionation process on Ме/Н–N–SO42–/ZrO2 composite catalytic systems, where N is MOR or MFI zeolite or Al2O3, was studied at atmospheric pressure in the interval 160–240°С. The catalyst of the composition 0.4Со/HZSM-5/SO42– (2.0)–ZrO2 at 180°С allows up to 63.5% of gaseous C4– alkanes to be involved in isomerization–disproportionation processing of the mixture of straight-run naphtha and propane–butane fraction (1 : 1 by weight), the content of C5–C6 alkanes in the catalyzate to be increased by 21.4%, and the relative content of their branched isomers to be increased to 88.8%. The effect of hydrogen on the conversion of С4– and С8+ components of the mixture of straight-run naphtha and propane–butane fraction (1 : 1 by weight) was studied; an increase in the Н2/hydrocarbon ratio from 2 to 4 leads to an increase in the conversion of С4– alkanes from 63.5 to 90%. The possibility of expanding the resources for producing С5–С6 alkanes with increased content of high-octane branched components by joint processing of the propane–butane fraction and straight-run naphtha was demonstrated.

The catalysts were synthesized based on the spent industrial aluminum-chromium catalyst used in the hydrocarbon dehydrogenation by SABIC Co., and the catalysts were modified with copper and potassium carbonate. The catalysts were tested in the oxidative dehydrogenation of ethylbenzene to styrene. It was found that the prepared and modified 1 wt % Cu catalyst, upon the conversion of ethylbenzene to styrene in the presence of O2, exhibits an activity of 53% with a selectivity for styrene of 85%. It was shown that the introduction of carbon dioxide into the reaction zone leads to an increase in activity to 60–63%, and selectivity to 89–91%. The stability of the functioning of a copper-promoted catalyst and the effect of water vapor on the process were studied. It was found that under conditions close to industrial, within 100 h, a stable conversion of the mixture (ethylbenzene : O2 = 9 : 1) : H2O = 4 : 1 with a selectivity for styrene of at least 90% at a space velocity of 2 h–1 (at liquid ethylbenzene).

Some of the most interesting and useful from the point of view of practical application are the issuesof heat and mass transfer modeling in the presence of physicochemical processes in real geometry areas. Such areasare the combustion chambers of various heat and power plants, and internal combustion engines.

The conversion of straight-run naphtha on composite catalytic systems containing HZSM-5 zeolite modified with 0.4 wt % Co or Ni and 15% SZ (10% SO 4 2- /ZrO2), performed at atmospheric pressure in the interval 140–200°C, was studied. At 140–200°C, the major products of straight-run naphtha conversion are branched C5−C6 alkanes. At T ≥ 180°C, the reaction products become enriched in gaseous alkanes. Analysis of the conversion products suggests that the process occurs via formation of a skeleton-isomerized intermediate, followed by its cleavage (disproportionation) at the β- or α-bond. The conversion is influenced by the conditions of the reaction and reduction of the composite catalytic system. On the Co-containing composite catalyst reduced at 380°C, the conversion of C8+ components of straight-run naphtha at 180°C, feed space velocity of 2.5 h−1, and H2/CH = 3 is 76.8%, and the content of C5−C6 alkanes consisting to 78% of isoparaffins reaches 61%.

Aim. Study of the state of intestinal microflora in young children seen in an outpatient setting with acute enteric infections. Methods. The state of microflora of 156 children was examined. All children underwent bacteriological study. Children were divided into following groups by age: 0-6 months - 59 (37.8%) patients; 6-12 months - 32 (20.5%) and 1-3 years - 65 (41.7%) subjects. Among them, 33 (21.1%) received breast milk, 46 (29.5%) received artificial feeding and 77 (49.4%) - mixed feeding. Results. Conditionally pathogenic bacteria were revealed in 114 (73.08%) patients, mainly (92.98% of cases) Candida alone or in combination with other conditionally pathogenic microorganisms were detected in 57 (50.0%) children: Candida + St. aureus - in 32 (28.1%) patients, Candida + P. vulgaris - in 9 (7.9%), Candida + P. vulgaris + St. aureus - in 12 (10.5%), Candida + St. aureus + Ps. aeroginosa - in 4 (3.5%) subjects. In 42 (26.92%) children conditionally pathogenic flora was not detected. As a result of the study of intestinal microflora structure of outpatients, decreased number of E. coli and B. bifidum by 67.3 and 36.5%, respectively, was revealed. The leading place was taken by Candida albicans identified in more than 50% of outpatients. Conclusion. Young children with acute enteric infections had mainly conditionally pathogenic and pathogenic microorganisms isolated in different associations.

The conversion of n-C7H16, n-C4H10 and mixtures of C7H16: n-C4H10 = 1: 0.3 on the composite catalysts Al2O3/WO 4 2– ∙ZrO2 (A-WZ) and HMOR/ WO 4 2– ∙ZrO2 (M-WZ) at atmospheric pressure, H2/hydrocarbon = 3 and temperatures of 140-200°C was studied. It was found that a mixture of C7H16: n-C4H10 on M-WZ with high selectivity is converted into C5–C6 isomers. An assumption was made about the mechanism of the formation of the bimolecular intermediate C11, which decays earlier than occurs the formation of the products of the conversion of the mixture C7H16: n-C4H10.

Clinical-neurophysiological bases of the combined use of Nucleo CMF forte preparation and interference therapy in the complex treatment of patients with vertebrogenic radiculopathies were studied. The beneficial effect of this therapeutic complex on the clinical course of the disease, more pronounced analgesic effect and regression of clinical manifestations, as well as improvement of quality of life indicators were proved. It has been established that the therapeutic effect of the complex application of Nucleo CMF forte and interference therapy lies in the improvement in the afferent and efferent links of the neuromotor apparatus, as well as the functional state of the spinal alpha-motoneurons associated with the acceleration of the regenerative processes. Activation of regenerative processes can also be associated with the restoration of certain morphological elements of the nervous system under the action of Nucleo CMF forte, as well as the normalization of the synthesis of complex lipids involved in cellular metabolism and synthesis of substances for the structural restoration of peripheral nerves. Carrying out neurotropic pharmacotherapy in combination with physiotherapy helps optimize therapeutic tactics in patients with vertebrogenic radiculopathies and is aimed at improving the quality of treatment, reducing the using of number of non-steroidal anti-inflammatory drugs and the frequency of relapse of the disease, and improving the quality of life of patients.

It has been established that the reason for the occurrence of nonlinear effect during the motion of water in microcracks is the magnitude of the distance between the upper and lower slabs, which in what follows will be called the crack thickness. It has been revealed for the first time that the reason for the manifestation of abnormal features in cracks is not only the wall layer but also the microcrack effect, i.e., an analog of the Jamin effect in a porous medium.

Objective: to determine the proportion of adenovirus gastroenteritides in the structure of acute enteric infections of uncertain etiology among the children of Baku. Subjects and methods. A total of 155 children aged less than 14 years with acute enteric infections of uncertain etiology who had been admitted to the Clinic of Infectious Diseases, V. Akhundov National Research Institute of Medical Prevention, in 2014–2015, were examined. The etiological diagnosis of adenovirus gastroenteritis was made by immunochromatographic assay. To rule out the bacterial etiology of acute enteric infection, all the children underwent fecal bacteriological examination. The examinees included babies under 6 months (17,4%), infants aged 7 months to 1 year (6,4%), those 1–2 years of age (29,6%), and children aged 2–14 years (46,4%). Adenoviruses in conjunction with rotavirus were detected in 7 (4,5%) patients. Adenovirus monoinfection was seen in 23 (15%) children. The contribution of adenoviruses in the etiological structure of acute enteric infections in children was 19,3%. There was no significant difference in the frequency of adenoviruses depending on gender. Adenovirus monoinfection wasregistered in the children all year round. Adenovirus monoinfection occurred as moderate diarrhea whereas mixed adenovirus-rotavirus infection was characterized by the severe course of diarrheal syndrome and catarrhal manifestations.

The purpose of this study was to study the state of the intestinal microflora in young children who received inpatient treatment for acute intestinal infections. A study of the microflora in 183 children aged 0 months. up to 3 years of life. At the same time, 43 (23.5%) children received breast milk, 53 (29.0%) were artificially fed and 87 (47.5%) mixed-fed children. All children were examined by bacteriological method. Conditionally pathogenic flora among hospitalized patients was detected in 114 (62.3%),Candidawas mainly detected in 67.5% of cases, in 57 patients (50.0%) in association with other opportunistic microorganisms —Candida + St. aureus— in 32 (28.1%),Candida + P. vulgaris —in 9 (7.9%),Candida + + P. vulgaris + St. aureus— in 12 (10.5%),Candida + St. aureus + Ps. aeroginosa— in 4 (3.5%). As a result of studying the composition of the intestinal microflora in patients hospitalized with intestinal infection, a decrease in the number ofE. coliandB. bifidumwas found, 43.7% and 63.4%, respectively.

The aim of the study was to define the role of brain-derived and glial cell line-derived neurotrophic factors (BDNF and GDNF) in realization of compensative and adaptive mechanisms of a neonatal organism to hypoxia. Materials and Methods The experiments in vivo have been carried out on pregnant C57BL/6 mice (n=36). Chronic hypobaric hypoxia has been modeled in different pregnancy trimesters. On gestation days E19–20, concentration of BDNF and GDNF in the blood of the pregnant females was determined by enzyme immunoassay. Further, the number of neonatal mice, their weight and body length parameters have been assessed. Parturient mothers (n=88) and their newborn babies followed up at the Clinic of Obstetrics and Gynecology of Pavlov University took part in the clinical investigations. Concentration of BDNF, GDNF, neuron-specific enolase (NSE), and hypoxia-inducible factor (HIF-1β) in the fetal cord blood has been determined by ELISA. The obtained data were retrospectively compared with cardiotocography, dopplerometry, presence of meconium-stained amniotic fluid and the neonate state at birth, assessment according to the Apgar score, and the course of adaptation period. Results Chronic hypobaric hypoxia in pregnant mice in trimester I and II resulted in the significant decrease of BDNF and GDNF level, decrease in the number of embryos, and in significant changes in weight/height characteristics of the newborn pups. According to the clinical observations, an increased expression of the neurotrophic factors BDNF, GDNF provides protection to a neonate even if hypoxia factors are present and realized. A low content of BDNF and GDNF was observed in the group of infants with a high risk of developing unfavorable hypoxic damaging effects. Conclusion The protective role of BDNF and GDNF in the regulation of fetal homeostasis in chronic hypoxia has been established experimentally and clinically.

The authors propose a procedure to determine the parameters of a medium on the basis of generalization of results obtained in steady-state motion of viscous and anomalous fluids in a plane-radial fracture. Also, the authors have developed a procedure to investigate the rheology of fluids and to determine the fracture opening and the equivalent permeability coefficient in a fracture system and have shown from these assessments the possibility of fluid inflow from a fractured-porous medium. It has been substantiated that the parameters of fracture and pore channels and rheophysical parameters of fluids in these channels can only be determined on the basis of experimental investigations.

Reaction of binucleophiles with 1,4- and 1,3-bis(2-chloro-2-cyanovinyl)benzenes, synthesized using a catalytic olefination of terephthalic and isophthalic aldehydes, gave high yields of aminopyrazoles, 3-amino-5-arylthiophene-2-carboxylic acid esters, and 2,4-diamino-6-arylpyrimidines.

Reaction of binucleophiles with 1,4- and 1,3-bis(2-chloro-2-cyanovinyl)benzenes, synthesized using a catalytic olefination of terephthalic and isophthalic aldehydes, gave high yields of aminopyrazoles, 3-amino-5-arylthiophene-2-carboxylic acid esters, and 2,4-diamino-6-arylpyrimidines.

Radical terpolymerizations of maleic anhydride (MA), trans-stilbene (Stb) and N-phenylmaleimide (PhMI) were carried out in methyl ethyl ketone (MEK) at 60-80 o C in the presence of 2,2'-azoisobutyronitrile (AIBN) as initiator. The terpolymerization was evaluated by using either the free monomer or complex participation models. The relative reactivity of MA toward poly(Stb) radical was found to be about 10,6 times lower than that of PhMI. The initial rate of copolymerization, the participation of the charge transfer complex (CTC) monomers and free monomers was quantitatively estimated. It was established that, even with a considerable change in the ratio of electron-acceptor monomers (MA and PhMI) in the initial reaction mixture, terpolymers possessed always a composition ratio close to 1:2:1. Constants for copolymerization of MA... Stb (M 1 ) and PhMI... Stb (M 3 ) were determined by using the Kelen-Tudos equation, and r 1 .K 1 /K 3 =0,03 and r 2 .K 3 /K 1 =0,08, where K 1 and K 3 are co of MA...Stb and PhMI...Stb complexes, respectively, were obtained. The result of kinetic studies of terpolymerization was interpreted as involving mainly alternating copolymerization of two complexomers with predominant participation in chain growth. Thermogravimetric analyses indicated the high thermal stabilities of terpolymers obtained

The radical terpolymerization reactions of the acceptor-donor-acceptor and donor-acceptor-donor systems, maleic anhydride (MA)-allyl propionate (AP)-methyl methacrylate (MMA) and styrene (St)-MMA-AP, had been studied. The terpolymerizations were carried out in methyl ethyl ketone at 60-75 °C in the presence of 2,2’-azoisobutyronitrile (ABIN) used as the initiator. Some kinetic parameters and copolymerization constants - for both, system were determined by dilatometric and Kelen-Tudos or Seiner-Lift methods. The obtained results are discussed in terms of the free monomer and complex chain growth models. It is shown that terpolymerization was carried out at a stage close to binary copolymerization of MA...AP complex with free MMA and St...MMA complex with AP in the both studied system, respectively. These systems are also used as model for interpretation of cyclocopolymerization mechanism in allyl methactylate-MA (or St) system. DTA and TGA analyses indicated the relatively high thermal stability of St-MMA-AP terpolymer. It is shown that this terpolymer decomposes through a one-step reaction at 310 °C, however MA-AP-MMA terpolymer decomposes through a multi-step reactions at 150, 260 and 310 °C.

Spectrum of serotypes of Coxsackie A virus and several others markers of virions, which cause enterovirus infection in children in Azerbaijan, was determined. Symptom of myotropism was used as a clinical sign. It was shown that enteroviruses were most frequently detected (41.1%) in children aged registered as enterovirus monoinfection. All isolated strains were characterized by such markers as cytopathic effect, delayed formation of plaques under the layer of agar with low content of sodium bicarbonate. Both attenuated and avirulent virions of Coxsackie A enteroviruses were detected.

The given functions ϕ ∈ R 1 , f ∈ R nare supposed to be continuous by the collection of arguments and have continuous second derivatives with respect to x and x, y; c ∈ R n×1 ; A, B, h(t) ∈ R n×n are given matrices, V ∈ R r is an open set. Firs constructive sufficient conditions for existence and uniqueness of the solution for boundary problem (2)-(3) are found. The formula of second order increment of functional (1) is calculated. The necessary condition of optimality for singular controls in classic sense is obtained in optimal control problem (1)-(4) on the basis of control variation.

The authors analyze results of the investigation of hemodynamics in the abdominal cavity vessels by the method of duplex scanning in 30 patients with acute cholecystitis, in 30 patients with mechanical jaundice and cholelithiasis and in 30 healthy subjects. It was found that these patients had less blood flow along the upper mesenterial artery and the portal vein. As a compensation the blood flow increased along the hepatic artery.

Fifty-six children with vascular hypertension, aged 8 to 14, were followed up. Ophthalmotonometric and ophthalmodynamometric examinations were carried out in 47 of these. Reduced vision acuity was detected in 25 percent of the examinees. The data of neuro-ophthalmologic examination evidence that in vascular hypertension functional hypertensive angiopathy of the retina may be observed in the fundus oculi already during the initial stages of the condition. The predominant sign was a moderate dilatation of the veins. Ophthalmodynamometric shifts presented as elevation of the systolic pressure mainly, and as the disease progressed in severity, diastolic pressure in the orbital artery grew as well, this being often associated with a reduction of visual functions.