Search

Your search keyword '"M. PIMENTA"' showing total 823 results
Start Over Author "M. PIMENTA"
823 results on '"M. PIMENTA"'

1. The gamma/hadron discriminator LCm in realistic air shower array experiments

Author

R. Conceição, P. J. Costa, L. Gibilisco, M. Pimenta, and B. Tomé

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract In this article, it is shown that the $$C_k$$ C k and LCm variables, recently introduced as an effective way to discriminate gamma and proton-induced showers in large wide-field gamma-ray observatories, can be generalised to be used in arrays of different detectors and variable fill factors. In particular, the $$C_k$$ C k profile discrimination capabilities are evaluated for scintillator and water Cherenkov detector arrays.

Published
2023
Full Text
View/download PDF

2. The Mercedes water Cherenkov detector

Author

P. Assis, A. Bakalová, U. Barres de Almeida, P. Brogueira, R. Conceição, A. De Angelis, L. Gibilisco, B. S. González, A. Guillén, G. La Mura, L. M. D. Mendes, L. F. Mendes, M. Pimenta, R. C. Shellard, B. Tomé, and J. Vícha

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The concept of a small, single-layer water Cherenkov detector, with three photomultiplier tubes (PMTs), placed at its bottom in a $$120^{\circ }$$ 120 ∘ star configuration (Mercedes Water Cherenkov Detector) is presented. The PMTs are placed near the lateral walls of the stations with an adjustable inclination and may be installed inside or outside the water volume. To illustrate the technical viability of this concept and obtain a first-order estimation of its cost, an engineering design was elaborated. The sensitivity of these stations to low energy Extensive Air Shower (EAS) electrons, photons and muons is discussed, both in compact and sparse array configurations. It is shown that the analysis of the intensity and time patterns of the PMT signals, using machine learning techniques, enables the tagging of muons, achieving an excellent gamma/hadron discrimination for TeV showers. This concept minimises the station production and maintenance costs, allowing for a highly flexible and fast installation. Mercedes Water Cherenkov Detectors (WCDs) are thus well-suited for use in high-altitude large gamma-ray observatories covering an extended energy range from the low energies, closing the gap between satellite and ground-based measurements, to very high energy regions, beyond the PeV scale.

Published
2022
Full Text
View/download PDF

3. The energy spectrum of cosmic rays beyond the turn-down around $$\varvec{10^{17}}$$ 10 17 eV as measured with the surface detector of the Pierre Auger Observatory

Author

P. Abreu, M. Aglietta, J. M. Albury, I. Allekotte, A. Almela, J. Alvarez-Muñiz, R. Alves Batista, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, P. R. Araújo Ferreira, J. C. Arteaga Velázquez, H. Asorey, P. Assis, G. Avila, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, R. J. Barreira Luz, K. H. Becker, J. A. Bellido, C. Berat, M. E. Bertaina, X. Bertou, P. L. Biermann, P. Billoir, V. Binet, K. Bismark, T. Bister, J. Biteau, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, L. Bonneau Arbeletche, N. Borodai, A. M. Botti, J. Brack, T. Bretz, P. G. Brichetto Orchera, F. L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, M. Büsken, K. S. Caballero-Mora, L. Caccianiga, F. Canfora, I. Caracas, J. M. Carceller, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, J. A. Chinellato, J. Chudoba, L. Chytka, R. W. Clay, A. C. Cobos Cerutti, R. Colalillo, A. Coleman, M. R. Coluccia, R. Conceição, A. Condorelli, G. Consolati, F. Contreras, F. Convenga, D. Correia dos Santos, C. E. Covault, S. Dasso, K. Daumiller, B. R. Dawson, J. A. Day, R. M. de Almeida, J. de Jesús, S. J. de Jong, G. De Mauro, J. R. T. de Mello Neto, I. De Mitri, J. de Oliveira, D. de Oliveira Franco, F. de Palma, V. de Souza, E. De Vito, M. del Río, O. Deligny, A. Di Matteo, C. Dobrigkeit, J. C. D’Olivo, L. M. Domingues Mendes, R. C. dos Anjos, D. dos Santos, M. T. Dova, J. Ebr, R. Engel, I. Epicoco, M. Erdmann, C. O. Escobar, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A. C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, B. Fick, J. M. Figueira, A. Filipčič, T. Fitoussi, T. Fodran, M. M. Freire, T. Fujii, A. Fuster, C. Galea, C. Galelli, B. García, A. L. Garcia Vegas, H. Gemmeke, F. Gesualdi, A. Gherghel-Lascu, P. L. Ghia, U. Giaccari, M. Giammarchi, J. Glombitza, F. Gobbi, F. Gollan, G. Golup, M. Gómez Berisso, P. F. Gómez Vitale, J. P. Gongora, J. M. González, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T. D. Grubb, F. Guarino, G. P. Guedes, E. Guido, S. Hahn, P. Hamal, M. R. Hampel, P. Hansen, D. Harari, V. M. Harvey, A. Haungs, T. Hebbeker, D. Heck, G. C. Hill, C. Hojvat, J. R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, A. Insolia, P. G. Isar, P. Janecek, J. A. Johnsen, J. Jurysek, A. Kääpä, K. H. Kampert, N. Karastathis, B. Keilhauer, J. Kemp, A. Khakurdikar, V. V. Kizakke Covilakam, H. O. Klages, M. Kleifges, J. Kleinfeller, M. Köpke, N. Kunka, B. L. Lago, R. G. Lang, N. Langner, M. A. Leigui de Oliveira, V. Lenok, A. Letessier-Selvon, I. Lhenry-Yvon, D. Lo Presti, L. Lopes, R. López, L. Lu, Q. Luce, J. P. Lundquist, A. Machado Payeras, G. Mancarella, D. Mandat, B. C. Manning, J. Manshanden, P. Mantsch, S. Marafico, A. G. Mariazzi, I. C. Mariş, G. Marsella, D. Martello, S. Martinelli, H. Martinez, O. Martínez Bravo, M. Mastrodicasa, H. J. Mathes, J. Matthews, G. Matthiae, E. Mayotte, P. O. Mazur, G. Medina-Tanco, D. Melo, A. Menshikov, K.-D. Merenda, S. Michal, M. I. Micheletti, L. Miramonti, D. Mockler, S. Mollerach, F. Montanet, C. Morello, M. Mostafá, A. L. Müller, M. A. Muller, K. Mulrey, R. Mussa, M. Muzio, W. M. Namasaka, A. Nasr-Esfahani, L. Nellen, M. Niculescu-Oglinzanu, M. Niechciol, D. Nitz, D. Nosek, V. Novotny, L. Nožka, A. Nucita, L. A. Núñez, M. Palatka, J. Pallotta, P. Papenbreer, G. Parente, A. Parra, J. Pawlowsky, M. Pech, F. Pedreira, J. Pȩkala, R. Pelayo, J. Peña-Rodriguez, E. E. Pereira Martins, J. Perez Armand, C. Pérez Bertolli, M. Perlin, L. Perrone, S. Petrera, T. Pierog, M. Pimenta, V. Pirronello, M. Platino, B. Pont, M. Pothast, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M. J. Roncoroni, M. Roth, E. Roulet, A. C. Rovero, P. Ruehl, S. J. Saffi, A. Saftoiu, F. Salamida, H. Salazar, G. Salina, J. D. Sanabria Gomez, F. Sánchez, E. M. Santos, E. Santos, F. Sarazin, R. Sarmento, C. Sarmiento-Cano, R. Sato, P. Savina, C. M. Schäfer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, P. Schovánek, F. G. Schröder, S. Schröder, J. Schulte, A. Schulz, S. J. Sciutto, M. Scornavacche, A. Segreto, S. Sehgal, R. C. Shellard, G. Sigl, G. Silli, O. Sima, R. Šmída, P. Sommers, J. F. Soriano, J. Souchard, R. Squartini, M. Stadelmaier, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, A. Streich, M. Suárez-Durán, T. Sudholz, T. Suomijärvi, A. D. Supanitsky, Z. Szadkowski, A. Tapia, C. Taricco, C. Timmermans, O. Tkachenko, P. Tobiska, C. J. Todero Peixoto, B. Tomé, Z. Torrès, A. Travaini, P. Travnicek, C. Trimarelli, M. Tueros, R. Ulrich, M. Unger, L. Vaclavek, M. Vacula, J. F. Valdés Galicia, L. Valore, E. Varela, A. Vásquez-Ramírez, D. Veberič, C. Ventura, I. D. Vergara Quispe, V. Verzi, J. Vicha, J. Vink, S. Vorobiov, H. Wahlberg, C. Watanabe, A. A. Watson, M. Weber, A. Weindl, L. Wiencke, H. Wilczyński, M. Wirtz, D. Wittkowski, B. Wundheiler, A. Yushkov, O. Zapparrata, E. Zas, D. Zavrtanik, M. Zavrtanik, L. Zehrer, and Pierre Auger Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present a measurement of the cosmic-ray spectrum above 100 PeV using the part of the surface detector of the Pierre Auger Observatory that has a spacing of 750 m. An inflection of the spectrum is observed, confirming the presence of the so-called second-knee feature. The spectrum is then combined with that of the 1500 m array to produce a single measurement of the flux, linking this spectral feature with the three additional breaks at the highest energies. The combined spectrum, with an energy scale set calorimetrically via fluorescence telescopes and using a single detector type, results in the most statistically and systematically precise measurement of spectral breaks yet obtained. These measurements are critical for furthering our understanding of the highest energy cosmic rays.

Published
2021
Full Text
View/download PDF

4. Muon identification in a compact single-layered water Cherenkov detector and gamma/hadron discrimination using machine learning techniques

Author

R. Conceição, B. S. González, A. Guillén, M. Pimenta, and B. Tomé

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The muon tagging is an essential tool to distinguish between gamma and hadron-induced showers in wide field-of-view gamma-ray observatories. In this work, it is shown that an efficient muon tagging (and counting) can be achieved using a water Cherenkov detector with a reduced water volume and 4 PMTs, provided that the PMT signal spatial and time patterns are interpreted by an analysis based on machine learning (ML). The developed analysis has been tested for different shower and array configurations. The output of the ML analysis, the probability of having a muon in the WCD station, has been used to notably discriminate between gamma and hadron induced showers with $$S/ \sqrt{B} \sim 4$$ S / B ∼ 4 for shower with energies $$E_0 \sim 1\,$$ E 0 ∼ 1 TeV. Finally, for proton-induced showers, an estimator of the number of muons was built by means of the sum of the probabilities of having a muon in the stations. Resolutions about $$20\%$$ 20 % and a negligible bias are obtained for vertical showers with $$N_{\mu } > 10$$ N μ > 10 .

Published
2021
Full Text
View/download PDF

5. New methods to reconstruct $$X_{\mathrm{max}}$$ X max and the energy of gamma-ray air showers with high accuracy in large wide-field observatories

Author

R. Conceição, L. Peres, M. Pimenta, and B. Tomé

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Novel methods to reconstruct the slant depth of the maximum of the longitudinal profile ( $$X_{\mathrm{max}}$$ X max ) of high-energy showers initiated by gamma-rays as well as their energy ( $$E_0$$ E 0 ) are presented. The methods were developed for gamma rays with energies ranging from a few hundred GeV to $$\sim 10$$ ∼ 10 TeV. An estimator of $$X_{\mathrm{max}}$$ X max is obtained, event-by-event, from its correlation with the distribution of the arrival time of the particles at the ground, or the signal at the ground for lower energies. An estimator of $$E_0$$ E 0 is obtained, event-by-event, using a parametrization that has as inputs the total measured energy at the ground, the amount of energy contained in a region near to the shower core and the estimated $$X_{\mathrm{max}}$$ X max . Resolutions about $$40 \, (20)\,\mathrm{g/cm^2}$$ 40 ( 20 ) g / cm 2 and about $$30 \, (20)\%$$ 30 ( 20 ) % for, respectively, $$X_{\mathrm{max}}$$ X max and $$E_0$$ E 0 at $$1 \, (10) \ \mathrm {TeV}$$ 1 ( 10 ) TeV energies are obtained, considering vertical showers. The obtained results are auspicious and can lead to the opening of new physics avenues for large wide field-of-view gamma-ray observatories. The dependence of the resolutions with experimental conditions is discussed.

Published
2021
Full Text
View/download PDF

6. Pγhα: A new variable for γ/h discrimination in large gamma-ray ground arrays

Author

R. Conceição, B.S. González, M. Pimenta, and B. Tomé

Subjects
Gamma-ray wide-field observatories, Extensive air showers, Gamma/hadron discrimination, Physics, QC1-999
Abstract

In this letter, a new strategy to enhance the discrimination of high energy gamma rays from the huge charged cosmic rays background in large cosmic rays ground arrays is presented. This strategy is based on the introduction of a new simple variable, Pγhα, which combines the probability of tagging muons and/or very energetic particles in each single array station. The discrimination power of this new variable, particularly important for and above multi-TeV energies, is illustrated for a few specific examples in the case of a hypothetical water Cherenkov detector cosmic ray array, both in the case of low and high particle stations occupancy. The results are very encouraging and hopefully will be demonstrated in the present and future gamma-ray Observatories.

Published
2022
Full Text
View/download PDF

7. Direct measurement of the muonic content of extensive air showers between $$\mathbf { 2\times 10^{17}}$$ 2×1017 and $$\mathbf {2\times 10^{18}}~$$ 2×1018 eV at the Pierre Auger Observatory

Author

A. Aab, P. Abreu, M. Aglietta, J. M. Albury, I. Allekotte, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, P. R. Araújo Ferreira, H. Asorey, P. Assis, G. Avila, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, R. J. Barreira Luz, K. H. Becker, J. A. Bellido, C. Berat, M. E. Bertaina, X. Bertou, P. L. Biermann, T. Bister, J. Biteau, A. Blanco, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, L. Bonneau Arbeletche, N. Borodai, A. M. Botti, J. Brack, T. Bretz, F. L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, K. S. Caballero-Mora, L. Caccianiga, L. Calcagni, A. Cancio, F. Canfora, I. Caracas, J. M. Carceller, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, J. A. Chinellato, K. Choi, J. Chudoba, L. Chytka, R. W. Clay, A. C. Cobos Cerutti, R. Colalillo, A. Coleman, M. R. Coluccia, R. Conceição, A. Condorelli, G. Consolati, F. Contreras, F. Convenga, C. E. Covault, S. Dasso, K. Daumiller, B. R. Dawson, J. A. Day, R. M. de Almeida, J. de Jesús, S. J. de Jong, G. De Mauro, J. R. T. de Mello Neto, I. De Mitri, J. de Oliveira, D. de Oliveira Franco, V. de Souza, J. Debatin, M. del Río, O. Deligny, N. Dhital, A. Di Matteo, M. L. Díaz Castro, C. Dobrigkeit, J. C. D’Olivo, Q. Dorosti, R. C. dos Anjos, M. T. Dova, J. Ebr, R. Engel, I. Epicoco, M. Erdmann, C. O. Escobar, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A. C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, B. Fick, J. M. Figueira, A. Filipčič, M. M. Freire, T. Fujii, A. Fuster, C. Galea, C. Galelli, B. García, A. L. Garcia Vegas, H. Gemmeke, F. Gesualdi, A. Gherghel-Lascu, P. L. Ghia, U. Giaccari, M. Giammarchi, M. Giller, J. Glombitza, F. Gobbi, G. Golup, M. Gómez Berisso, P. F. Gómez Vitale, J. P. Gongora, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T. D. Grubb, F. Guarino, G. P. Guedes, E. Guido, S. Hahn, R. Halliday, M. R. Hampel, P. Hansen, D. Harari, V. M. Harvey, A. Haungs, T. Hebbeker, D. Heck, G. C. Hill, C. Hojvat, J. R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, J. Hulsman, A. Insolia, P. G. Isar, J. A. Johnsen, J. Jurysek, A. Kääpä, K. H. Kampert, B. Keilhauer, J. Kemp, H. O. Klages, M. Kleifges, J. Kleinfeller, M. Köpke, G. Kukec Mezek, B. L. Lago, D. LaHurd, R. G. Lang, M. A. Leigui de Oliveira, V. Lenok, A. Letessier-Selvon, I. Lhenry-Yvon, D. Lo Presti, L. Lopes, R. López, A. López Casado, R. Lorek, Q. Luce, A. Lucero, A. Machado Payeras, M. Malacari, G. Mancarella, D. Mandat, B. C. Manning, J. Manshanden, P. Mantsch, A. G. Mariazzi, I. C. Mariş, G. Marsella, D. Martello, H. Martinez, O. Martínez Bravo, M. Mastrodicasa, H. J. Mathes, J. Matthews, G. Matthiae, E. Mayotte, P. O. Mazur, G. Medina-Tanco, D. Melo, A. Menshikov, K.-D. Merenda, S. Michal, M. I. Micheletti, L. Miramonti, D. Mockler, S. Mollerach, F. Montanet, C. Morello, M. Mostafá, A. L. Müller, M. A. Muller, S. Müller, R. Mussa, M. Muzio, W. M. Namasaka, L. Nellen, M. Niculescu-Oglinzanu, M. Niechciol, D. Nitz, D. Nosek, V. Novotny, L. Nožka, A Nucita, L. A. Núñez, M. Palatka, J. Pallotta, M. P. Panetta, P. Papenbreer, G. Parente, A. Parra, M. Pech, F. Pedreira, J. Pȩkala, R. Pelayo, J. Peña-Rodriguez, J. Perez Armand, M. Perlin, L. Perrone, C. Peters, S. Petrera, T. Pierog, M. Pimenta, V. Pirronello, M. Platino, B. Pont, M. Pothast, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, P. Ristori, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M. J. Roncoroni, M. Roth, E. Roulet, A. C. Rovero, P. Ruehl, S. J. Saffi, A. Saftoiu, F. Salamida, H. Salazar, G. Salina, J. D. Sanabria Gomez, F. Sánchez, E. M. Santos, E. Santos, F. Sarazin, R. Sarmento, C. Sarmiento-Cano, R. Sato, P. Savina, C. Schäfer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, P. Schovánek, F. G. Schröder, S. Schröder, S. J. Sciutto, M. Scornavacche, R. C. Shellard, G. Sigl, G. Silli, O. Sima, R. Šmída, P. Sommers, J. F. Soriano, J. Souchard, R. Squartini, M. Stadelmaier, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, A. Streich, M. Suárez-Durán, T. Sudholz, T. Suomijärvi, A. D. Supanitsky, J. Šupík, Z. Szadkowski, A. Taboada, O. A. Taborda, A. Tapia, C. Timmermans, P. Tobiska, C. J. Todero Peixoto, B. Tomé, G. Torralba Elipe, A. Travaini, P. Travnicek, C. Trimarelli, M. Trini, M. Tueros, R. Ulrich, M. Unger, M. Urban, L. Vaclavek, J. F. Valdés Galicia, I. Valiño, L. Valore, A. van Vliet, E. Varela, B. Vargas Cárdenas, A. Vásquez-Ramírez, D. Veberič, C. Ventura, I. D. Vergara Quispe, V. Verzi, J. Vicha, L. Villaseñor, J. Vink, S. Vorobiov, H. Wahlberg, A. A. Watson, M. Weber, A. Weindl, L. Wiencke, H. Wilczyński, T. Winchen, M. Wirtz, D. Wittkowski, B. Wundheiler, A. Yushkov, O. Zapparrata, E. Zas, D. Zavrtanik, M. Zavrtanik, L. Zehrer, A. Zepeda, M. Ziolkowski, F. Zuccarello, and The Pierre Auger Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The hybrid design of the Pierre Auger Observatory allows for the measurement of the properties of extensive air showers initiated by ultra-high energy cosmic rays with unprecedented precision. By using an array of prototype underground muon detectors, we have performed the first direct measurement, by the Auger Collaboration, of the muon content of air showers between $$2\times 10^{17}$$ 2×1017 and $$2\times 10^{18}$$ 2×1018 eV. We have studied the energy evolution of the attenuation-corrected muon density, and compared it to predictions from air shower simulations. The observed densities are found to be larger than those predicted by models. We quantify this discrepancy by combining the measurements from the muon detector with those from the Auger fluorescence detector at $$10^{{17.5}}\, {\mathrm{eV}} $$ 1017.5eV and $$10^{{18}}\, {\mathrm{eV}} $$ 1018eV . We find that, for the models to explain the data, an increase in the muon density of $$38\%$$ 38% $$\pm 4\% (12\%)$$ ±4%(12%) $$\pm {}^{21\%}_{18\%}$$ ±18%21% for EPOS-LHC, and of $$50\% (53\%)$$ 50%(53%) $$\pm 4\% (13\%)$$ ±4%(13%) $$\pm {}^{23\%}_{20\%}$$ ±20%23% for QGSJetII-04, is respectively needed.

Published
2020
Full Text
View/download PDF

8. Search for Ultra-high-energy Photons from Gravitational Wave Sources with the Pierre Auger Observatory

Author

A. Abdul Halim, P. Abreu, M. Aglietta, I. Allekotte, K. Almeida Cheminant, A. Almela, J. Alvarez-Muñiz, J. Ammerman Yebra, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, P. R. Araújo Ferreira, E. Arnone, J. C. Arteaga Velázquez, H. Asorey, P. Assis, G. Avila, E. Avocone, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, J. A. Bellido, C. Berat, M. E. Bertaina, G. Bhatta, P. L. Biermann, V. Binet, K. Bismark, T. Bister, J. Biteau, J. Blazek, C. Bleve, J. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, L. Bonneau Arbeletche, N. Borodai, J. Brack, T. Bretz, P. G. Brichetto Orchera, F. L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, M. Büsken, A. Bwembya, K. S. Caballero-Mora, L. Caccianiga, I. Caracas, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, J. A. Chinellato, J. Chudoba, L. Chytka, R. W. Clay, A. C. Cobos Cerutti, R. Colalillo, A. Coleman, M. R. Coluccia, R. Conceiçao, A. Condorelli, G. Consolati, M. Conte, F. Contreras, F. Convenga, D. Correia dos Santos, P. J. Costa, C. E. Covault, M. Cristinziani, C. S. Cruz Sanchez, S. Dasso, K. Daumiller, B. R. Dawson, R. M. de Almeida, J. de Jesús, S. J. de Jong, J. R. T. de Mello Neto, I. De Mitri, J. de Oliveira, D. de Oliveira Franco, F. de Palma, V. de Souza, E. De Vito, A. Del Popolo, O. Deligny, L. Deval, A. di Matteo, M. Dobre, C. Dobrigkeit, J. C. D’Olivo, L. M. Domingues Mendes, R. C. dos Anjos, J. Ebr, M. Emam, R. Engel, I. Epicoco, M. Erdmann, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A. C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, A. Fernandes, B. Fick, J. M. Figueira, A. Filipčič, T. Fitoussi, B. Flaggs, T. Fodran, T. Fujii, A. Fuster, C. Galea, C. Galelli, B. García, H. Gemmeke, F. Gesualdi, A. Gherghel-Lascu, P. L. Ghia, U. Giaccari, M. Giammarchi, J. Glombitza, F. Gobbi, F. Gollan, G. Golup, M. Gómez Berisso, P. F. Gómez Vitale, J. P. Gongora, J. M. González, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T. D. Grubb, F. Guarino, G. P. Guedes, E. Guido, S. Hahn, P. Hamal, M. R. Hampel, P. Hansen, D. Harari, V. M. Harvey, A. Haungs, T. Hebbeker, D. Heck, C. Hojvat, J. R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, A. Insolia, P. G. Isar, P. Janecek, J. A. Johnsen, J. Jurysek, A. Kääpä, K. H. Kampert, B. Keilhauer, A. Khakurdikar, V. V. Kizakke Covilakam, H. O. Klages, M. Kleifges, J. Kleinfeller, F. Knapp, N. Kunka, B. L. Lago, N. Langner, M. A. Leigui de Oliveira, V. Lenok, A. Letessier-Selvon, I. Lhenry-Yvon, D. Lo Presti, L. Lopes, R. López, L. Lu, Q. Luce, J. P. Lundquist, A. Machado Payeras, M. Majercakova, D. Mandat, B. C. Manning, J. Manshanden, P. Mantsch, S. Marafico, F. M. Mariani, A. G. Mariazzi, I. C. Mariş, G. Marsella, D. Martello, S. Martinelli, O. Martínez Bravo, M. A. Martins, M. Mastrodicasa, H. J. Mathes, J. Matthews, G. Matthiae, E. Mayotte, S. Mayotte, P. O. Mazur, G. Medina-Tanco, J. Meinert, D. Melo, A. Menshikov, S. Michal, M. I. Micheletti, L. Miramonti, S. Mollerach, F. Montanet, L. Morejon, C. Morello, A. L. Müller, K. Mulrey, R. Mussa, M. Muzio, W. M. Namasaka, A. Nasr-Esfahani, L. Nellen, G. Nicora, M. Niculescu-Oglinzanu, M. Niechciol, D. Nitz, I. Norwood, D. Nosek, V. Novotny, L. Nožka, A. Nucita, L. A. Núñez, C. Oliveira, M. Palatka, J. Pallotta, G. Parente, A. Parra, J. Pawlowsky, M. Pech, J. Pȩkala, R. Pelayo, L. A. S. Pereira, E. E. Pereira Martins, J. Perez Armand, C. Pérez Bertolli, L. Perrone, S. Petrera, C. Petrucci, T. Pierog, M. Pimenta, M. Platino, B. Pont, M. Pothast, M. Pourmohammad Shavar, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M. J. Roncoroni, S. Rossoni, M. Roth, E. Roulet, A. C. Rovero, P. Ruehl, A. Saftoiu, M. Saharan, F. Salamida, H. Salazar, G. Salina, J. D. Sanabria Gomez, F. Sánchez, E. M. Santos, E. Santos, F. Sarazin, R. Sarmento, R. Sato, P. Savina, C. M. Schäfer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, H. Schoorlemmer, P. Schovánek, F. G. Schröder, J. Schulte, T. Schulz, S. J. Sciutto, M. Scornavacche, A. Segreto, S. Sehgal, S. U. Shivashankara, G. Sigl, G. Silli, O. Sima, R. Smau, R. Šmída, P. Sommers, J. F. Soriano, R. Squartini, M. Stadelmaier, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, M. Straub, A. Streich, M. Suárez-Durán, T. Suomijärvi, A. D. Supanitsky, Z. Szadkowski, A. Tapia, C. Taricco, C. Timmermans, O. Tkachenko, P. Tobiska, C. J. Todero Peixoto, B. Tomé, Z. Torrès, A. Travaini, P. Travnicek, C. Trimarelli, M. Tueros, R. Ulrich, M. Unger, L. Vaclavek, M. Vacula, J. F. Valdés Galicia, L. Valore, E. Varela, A. Vásquez-Ramírez, D. Veberič, C. Ventura, I. D. Vergara Quispe, V. Verzi, J. Vicha, J. Vink, S. Vorobiov, C. Watanabe, A. A. Watson, A. Weindl, L. Wiencke, H. Wilczyński, D. Wittkowski, B. Wundheiler, A. Yushkov, O. Zapparrata, E. Zas, D. Zavrtanik, M. Zavrtanik, and The Pierre Auger Collaboration

Subjects
Particle astrophysics, Ultra-high-energy cosmic radiation, Cosmic ray showers, Gravitational wave sources, Transient sources, Astrophysics, QB460-466
Abstract

A search for time-directional coincidences of ultra-high-energy (UHE) photons above 10 EeV with gravitational wave (GW) events from the LIGO/Virgo runs O1 to O3 is conducted with the Pierre Auger Observatory. Due to the distinctive properties of photon interactions and to the background expected from hadronic showers, a subset of the most interesting GW events is selected based on their localization quality and distance. Time periods of 1000 s around and 1 day after the GW events are analyzed. No coincidences are observed. Upper limits on the UHE photon fluence from a GW event are derived that are typically at ∼7 MeV cm ^−2 (time period 1000 s) and ∼35 MeV cm ^−2 (time period 1 day). Due to the proximity of the binary neutron star merger GW170817, the energy of the source transferred into UHE photons above 40 EeV is constrained to be less than 20% of its total GW energy. These are the first limits on UHE photons from GW sources.

Published
2023
Full Text
View/download PDF

9. A Catalog of the Highest-energy Cosmic Rays Recorded during Phase I of Operation of the Pierre Auger Observatory

Author

A. Abdul Halim, P. Abreu, M. Aglietta, I. Allekotte, P. Allison, K. Almeida Cheminant, A. Almela, J. Alvarez-Muñiz, J. Ammerman Yebra, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, P. R. Araújo Ferreira, E. Arnone, J. C. Arteaga Velázquez, H. Asorey, P. Assis, M. Ave, G. Avila, E. Avocone, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, J. Beatty, J. A. Bellido, C. Berat, M. E. Bertaina, X. Bertou, G. Bhatta, P. L. Biermann, P. Billoir, V. Binet, K. Bismark, T. Bister, J. Biteau, J. Blazek, C. Bleve, J. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, L. Bonneau Arbeletche, N. Borodai, J. Brack, T. Bretz, P. G. Brichetto Orchera, F. L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, M. Büsken, A. Bwembya, K. S. Caballero-Mora, L. Caccianiga, I. Caracas, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, R. Cester, J. A. Chinellato, J. Chirinos, J. Chudoba, L. Chytka, R. W. Clay, A. C. Cobos Cerutti, R. Colalillo, A. Coleman, M. R. Coluccia, R. Conceição, A. Condorelli, G. Consolati, F. Contreras, F. Convenga, D. Correia dos Santos, C. E. Covault, M. Cristinziani, C. S. Cruz Sanchez, S. Dasso, K. Daumiller, B. R. Dawson, R. M. de Almeida, J. de Jesús, S. J. de Jong, J. R. T. de Mello Neto, I. De Mitri, J. de Oliveira, D. de Oliveira Franco, F. de Palma, V. de Souza, E. De Vito, A. Del Popolo, O. Deligny, L. Deval, A. di Matteo, M. Dobre, C. Dobrigkeit, J. C. D’Olivo, L. M. Domingues Mendes, A. Dorofeev, R. C. dos Anjos, J. Ebr, M. Eman, R. Engel, I. Epicoco, M. Erdmann, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A. C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, B. Fick, J. M. Figueira, A. Filipčič, T. Fitoussi, B. Flaggs, T. Fodran, T. Fujii, A. Fuster, C. Galea, C. Galelli, B. García, H. Gemmeke, F. Gesualdi, A. Gherghel-Lascu, P. L. Ghia, U. Giaccari, M. Giammarchi, J. Glombitza, F. Gobbi, F. Gollan, G. Golup, M. Gómez Berisso, P. F. Gómez Vitale, J. P. Gongora, J. M. González, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T. D. Grubb, F. Guarino, G. P. Guedes, E. Guido, S. Hahn, P. Hamal, M. R. Hampel, P. Hansen, D. Harari, J. Harton, V. M. Harvey, A. Haungs, T. Hebbeker, D. Heck, C. Hojvat, J. R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, A. Insolia, P. G. Isar, P. Janecek, J. A. Johnsen, J. Jurysek, A. Kääpä, K. H. Kampert, B. Keilhauer, A. Khakurdikar, V. V. Kizakke Covilakam, H. O. Klages, M. Kleifges, J. Kleinfeller, F. Knapp, J. Knapp, N. Kunka, C. Lachaud, B. L. Lago, N. Langner, M. A. Leigui de Oliveira, V. Lenok, A. Letessier-Selvon, I. Lhenry-Yvon, D. Lo Presti, L. Lopes, R. López, L. Lu, Q. Luce, J. P. Lundquist, A. Machado Payeras, D. Mandat, B. C. Manning, J. Manshanden, P. Mantsch, S. Marafico, F. M. Mariani, A. G. Mariazzi, I. C. Mariş, G. Marsella, D. Martello, S. Martinelli, O. Martínez Bravo, M. A. Martins, M. Mastrodicasa, H. J. Mathes, J. Matthews, G. Matthiae, E. Mayotte, S. Mayotte, P. O. Mazur, G. Medina-Tanco, J. Meinert, D. Melo, A. Menshikov, S. Michal, M. I. Micheletti, L. Miramonti, S. Mollerach, F. Montanet, L. Morejon, C. Morello, A. L. Müller, K. Mulrey, R. Mussa, M. Muzio, W. M. Namasaka, A. Nasr-Esfahani, L. Nellen, G. Nicora, M. Niculescu-Oglinzanu, M. Niechciol, D. Nitz, I. Norwood, D. Nosek, V. Novotny, L. Nožka, A Nucita, L. A. Núñez, C. Oliveira, M. Palatka, J. Pallotta, G. Parente, A. Parra, J. Pawlowsky, M. Pech, J. Pȩkala, R. Pelayo, E. E. Pereira Martins, J. Perez Armand, C. Pérez Bertolli, L. Perrone, S. Petrera, C. Petrucci, T. Pierog, M. Pimenta, M. Platino, B. Pont, M. Pothast, M. Pourmohammad Shavar, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M. J. Roncoroni, S. Rossoni, M. Roth, E. Roulet, A. C. Rovero, P. Ruehl, A. Saftoiu, M. Saharan, F. Salamida, H. Salazar, G. Salina, J. D. Sanabria Gomez, F. Sánchez, E. M. Santos, E. Santos, F. Sarazin, R. Sarmento, R. Sato, P. Savina, C. M. Schäfer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, H. Schoorlemmer, P. Schovánek, F. G. Schröder, J. Schulte, T. Schulz, S. J. Sciutto, M. Scornavacche, A. Segreto, S. Sehgal, S. U. Shivashankara, G. Sigl, G. Silli, O. Sima, R. Smau, R. Šmída, P. Sommers, J. F. Soriano, R. Squartini, M. Stadelmaier, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, M. Straub, A. Streich, M. Suárez-Durán, T. Sudholz, T. Suomijärvi, A. D. Supanitsky, Z. Szadkowski, A. Tapia, C. Taricco, C. Timmermans, O. Tkachenko, P. Tobiska, C. J. Todero Peixoto, B. Tomé, Z. Torrès, A. Travaini, P. Travnicek, C. Trimarelli, M. Tueros, R. Ulrich, M. Unger, L. Vaclavek, M. Vacula, J. F. Valdés Galicia, L. Valore, E. Varela, A. Vásquez-Ramírez, D. Veberič, C. Ventura, I. D. Vergara Quispe, V. Verzi, J. Vicha, L. M. Villase nor Cendejas, J. Vink, S. Vorobiov, C. Watanabe, A. A. Watson, A. Weindl, L. Wiencke, H. Wilczyński, D. Wittkowski, B. Wundheiler, P. Younk, A. Yushkov, O. Zapparrata, E. Zas, D. Zavrtanik, M. Zavrtanik, and (The Pierre Auger Collaboration)

Subjects
Ultra-high-energy cosmic radiation, Cosmic ray showers, Experimental data, Catalogs, Astrophysics, QB460-466
Abstract

A catalog containing details of the highest-energy cosmic rays recorded through the detection of extensive air showers at the Pierre Auger Observatory is presented with the aim of opening the data to detailed examination. Descriptions of the 100 showers created by the highest-energy particles recorded between 2004 January 1 and 2020 December 31 are given for cosmic rays that have energies in the range 78–166 EeV. Details are also given on a further nine very energetic events that have been used in the calibration procedure adopted to determine the energy of each primary. A sky plot of the arrival directions of the most energetic particles is shown. No interpretations of the data are offered.

Published
2023
Full Text
View/download PDF

11. Low-level laser therapy in neurosensory recovery – case series in dental and maxillofacial rehabilitation

Author

T. Nunes, S. Alves, M. Pimenta, S. Rocha, C. Caetano, and A. Corte-Real

Subjects
Medicine
Abstract

AbstractIntroduction Neurosensory disorders may be considered as a complication from surgical procedures, such as dental implants and mandibular osteotomy [1–3]. In these cases, the orofacial damage can involve general and professional patient impairments. Low-level laser therapy (LLLT) has been reported to be effective in reducing neurosensory recovery time, while promoting nerve regeneration [4,5]. This study aimed to analyse the LLLT impact on postsurgical neurosensory recovery, namely for dental and maxillofacial surgery patients.Materials and methods Patients previously submitted to dental and/or maxilofacial rehabilitation at Centro Hospitalar Universitário de Coimbra/Faculty of Medicine, University of Coimbra, were selected. Anamnesis, examination and neurosensory evaluation were performed to determine the presence and location of neurosensory disorder. The elected orofacial area was irradiated using a continuous wave diode laser at 660 nm (SIROLaser Blue; Sirona, Bensheim, Germany) in two sessions per week, until satisfactory results were achieved. The measure of health-related quality of life was performed by EQ-5D-5L questionnaire, before and after the LLLT treatment. This study was approved by the ethics committee of Faculty of Medicine of the University of Coimbra and the informed consent document was performed.Results Two patients (both Female, Age 22) were selected. Treatment lasted approximately 1 months in both cases. The mean score before and after treatment (0–100 scale), of the EQ-5D-5L questionnaire was 70.0–95.5.The recovery of the neurosensory disorder allowed the quality improvement in all 5 dimensions: mobility, self-care, daily activities, pain/discomfort and anxiety/depression. No reactions or side-effects were reported.Discussion and conclusions 5 dimensions of health quality were analysed and the severity level degrees were related with the corporal/patient impairment. The results supported the use of LLLT as an effective treatment option by accelerating the recovery of postsurgical neurosensory disturbances, improving the patient’s health.

Published
2021
Full Text
View/download PDF

12. A 3‐Year Sample of Almost 1,600 Elves Recorded Above South America by the Pierre Auger Cosmic‐Ray Observatory

Author

A. Aab, P. Abreu, M. Aglietta, I. F. M. Albuquerque, J. M. Albury, I. Allekotte, A. Almela, J. Alvarez Castillo, J. Alvarez‐Muñiz, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, H. Asorey, P. Assis, G. Avila, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, R. J. Barreira Luz, S. Baur, K. H. Becker, J.A. Bellido, C. Berat, M. E. Bertaina, X. Bertou, P. L. Biermann, J. Biteau, S. G. Blaess, A. Blanco, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, N. Borodai, A. M. Botti, J. Brack, T. Bretz, A. Bridgeman, F. L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, K. S. Caballero‐Mora, L. Caccianiga, L. Calcagni, A. Cancio, F. Canfora, J. M. Carceller, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, J. A. Chinellato, J. Chudoba, L. Chytka, R.W. Clay, A. C. Cobos Cerutti, R. Colalillo, A. Coleman, M. R. Coluccia, R. Conceição, A. Condorelli, G. Consolati, F. Contreras, M. J. Cooper, S. Coutu, C. E. Covault, B. Daniel, S. Dasso, K. Daumiller, B. R. Dawson, J. A. Day, R. M. deAlmeida, S. J. deJong, G. Mauro, J. R. T. deMello Neto, I. Mitri, J. deOliveira, F. O. deOliveira Salles, V. deSouza, J. Debatin, M. delRío, O. Deligny, N. Dhital, M. L. Díaz Castro, F. Diogo, C. Dobrigkeit, J. C. D'Olivo, Q. Dorosti, R. C. dosAnjos, M. T. Dova, A. Dundovic, J. Ebr, R. Engel, M. Erdmann, C. O. Escobar, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A. C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, L. P. Ferreyro, J. M. Figueira, A. Filipčič, M. M. Freire, T. Fujii, A. Fuster, B. García, H. Gemmeke, A. Gherghel‐Lascu, P. L. Ghia, U. Giaccari, M. Giammarchi, M. Giller, D. Głas, J. Glombitza, F. Gobbi, G. Golup, M. Gómez Berisso, P. F. Gómez Vitale, J. P. Gongora, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T. D. Grubb, F. Guarino, G. P. Guedes, E. Guido, R. Halliday, M. R. Hampel, P. Hansen, D. Harari, T. A. Harrison, V. M. Harvey, A. Haungs, T. Hebbeker, D. Heck, P. Heimann, G. C. Hill, C. Hojvat, E. M. Holt, P. Homola, J. R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, J. Hulsman, A. Insolia, P. G. Isar, I. Jandt, J. A. Johnsen, M. Josebachuili, J. Jurysek, A. Kääpä, K. H. Kampert, B. Keilhauer, N. Kemmerich, J. Kemp, H. O. Klages, M. Kleifges, J. Kleinfeller, R. Krause, D. Kuempel, G. Kukec Mezek, A. Kuotb Awad, B. L. Lago, D. LaHurd, R. G. Lang, R. Legumina, M. A. Leigui de Oliveira, V. Lenok, A. Letessier‐Selvon, I. Lhenry‐Yvon, O. C. Lippmann, D. Lo Presti, L. Lopes, R. López, A. López Casado, R. Lorek, Q. Luce, A. Lucero, M. Malacari, G. Mancarella, D. Mandat, B. C. Manning, P. Mantsch, A. G. Mariazzi, I. C. Mariş, G. Marsella, D. Martello, H. Martinez, O. Martínez Bravo, M. Mastrodicasa, H. J. Mathes, S. Mathys, J. Matthews, G. Matthiae, E. Mayotte, P. O. Mazur, G. Medina‐Tanco, D. Melo, A. Menshikov, K.‐D. Merenda, S. Michal, M. I. Micheletti, L. Middendorf, L. Miramonti, B. Mitrica, D. Mockler, S. Mollerach, F. Montanet, C. Morello, G. Morlino, M. Mostafá, A. L. Müller, M. A. Muller, S. Müller, R. Mussa, L. Nellen, P. H. Nguyen, M. Niculescu‐Oglinzanu, M. Niechciol, D. Nitz, D. Nosek, V. Novotny, L. Noža, A Nucita, L.A. Núñez, A. Olinto, M. Palatka, J. Pallotta, M. P. Panetta, P. Papenbreer, G. Parente, A. Parra, M. Pech, F. Pedreira, J. Pękala, R. Pelayo, J. Peña‐Rodriguez, L. A. S. Pereira, M. Perlin, L. Perrone, C. Peters, S. Petrera, J. Phuntsok, T. Pierog, M. Pimenta, V. Pirronello, M. Platino, J. Poh, B. Pont, C. Porowski, R. R. Prado, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, S. Quinn, R. Ramos‐Pollan, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, P. Ristori, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M. J. Roncoroni, M. Roth, E. Roulet, A. C. Rovero, P. Ruehl, S. J. Saffi, A. Saftoiu, F. Salamida, H. Salazar, G. Salina, J. D. Sanabria Gomez, F. Sánchez, E. M. Santos, E. Santos, F. Sarazin, R. Sarmento, C. Sarmiento‐Cano, R. Sato, P. Savina, M. Schauer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, P. Schovánek, F. G. Schröder, S. Schröder, J. Schumacher, S. J. Sciutto, M. Scornavacche, R. C. Shellard, G. Sigl, G. Silli, O. Sima, R. Šmída, G.R. Snow, P. Sommers, J. F. Soriano, J. Souchard, R. Squartini, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, M. Stolpovskiy, A. Streich, F. Suarez, M. Suárez‐Durán, T. Sudholz, T. Suomijärvi, A.D. Supanitsky, J. Šupík, Z. Szadkowski, A. Taboada, O. A. Taborda, A. Tapia, C. Timmermans, C. J. Todero Peixoto, B. Tomé, G. Torralba Elipe, A. Travaini, P. Travnicek, M. Trini, M. Tueros, R. Ulrich, M. Unger, M. Urban, J. F. Valdés Galicia, I. Valiño, L. Valore, P. vanBodegom, A. M. van denBerg, A. vanVliet, E. Varela, B. Vargas Cárdenas, D. Veberič, C. Ventura, I. D. Vergara Quispe, V. Verzi, J. Vicha, L. Villaseñor, J. Vink, S. Vorobiov, H. Wahlberg, A. A. Watson, M. Weber, A. Weindl, M. Wiedeński, L. Wiencke, H. Wilczyński, T. Winchen, M. Wirtz, D. Wittkowski, B. Wundheiler, L. Yang, A. Yushkov, E. Zas, D. Zavrtanik, M. Zavrtanik, L. Zehrer, A. Zepeda, B. Zimmermann, M. Ziolkowski, Z. Zong, and F. Zuccarello

Subjects
Astronomy, QB1-991, Geology, QE1-996.5
Abstract

Abstract Elves are a class of transient luminous events, with a radial extent typically greater than 250 km, that occur in the lower ionosphere above strong electrical storms. We report the observation of 1,598 elves, from 2014 to 2016, recorded with unprecedented time resolution (100 ns) using the fluorescence detector (FD) of the Pierre Auger Cosmic‐Ray Observatory. The Auger Observatory is located in the Mendoza province of Argentina with a viewing footprint for elve observations of 3·106 km 2, reaching areas above the Pacific and Atlantic Oceans, as well as the Córdoba region, which is known for severe convective thunderstorms. Primarily designed for ultrahigh energy cosmic‐ray observations, the Auger FD turns out to be very sensitive to the ultraviolet emission in elves. The detector features modified Schmidt optics with large apertures resulting in a field of view that spans the horizon, and year‐round operation on dark nights with low moonlight background, when the local weather is favorable. The measured light profiles of 18% of the elve events have more than one peak, compatible with intracloud activity. Within the 3‐year sample, 72% of the elves correlate with the far‐field radiation measurements of the World Wide Lightning Location Network. The Auger Observatory plans to continue operations until at least 2025, including elve observations and analysis. To the best of our knowledge, this observatory is the only facility on Earth that measures elves with year‐round operation and full horizon coverage.

Published
2020
Full Text
View/download PDF

13. Young People's Coping Strategies When Dealing with Their Own and a Friend's Symptoms of Poor Mental Health: A Qualitative Study

Author

Sofia M. Pimenta, Simon C. Hunter, Susan Rasmussen, Nicola Cogan, and Bethany Martin

Abstract

Young people struggle to seek help for their mental health, despite having different resources available. As the coping process is very complex, and elements such as trust and availability of resources have been said to influence it, this study aimed to understand how young people cope with their own or a friend's symptoms of poor mental health. Eleven young people (13-15 years old) were interviewed. Thematic Analysis of the interviews showed that participants reported different coping strategies for dealing with their own hypothetical symptoms and those of a friend. Participants identified the social impact of experiencing symptoms of poor mental health and choice of resources as the main factors influencing their coping strategies. For their own symptoms, young people expressed concern about being judged and that they would only disclose to someone they trust. Participants would not disclose a friend's symptoms because they did not want to break their trust. Finally, choice of resources was mainly influenced by the severity of symptoms being experienced, especially when it comes to asking for professional help. This study contributes to a better understanding of the different ways in which young people cope with their own symptoms and symptoms experienced by a friend.

Published
2024
Full Text
View/download PDF

14. Multi-Messenger Physics With the Pierre Auger Observatory

Author

Karl-Heinz Kampert, Miguel Alejandro Mostafa, Enrique Zas, The Pierre Auger Collaboration, A. Aab, P. Abreu, M. Aglietta, I.F.M. Albuquerque, J.M. Albury, I. Allekotte, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, G.A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, H. Asorey, P. Assis, G. Avila, A.M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, R.J. Barreira Luz, S. Baur, K.H. Becker, J.A. Bellido, C. Berat, M.E. Bertaina, X. Bertou, P.L. Biermann, J. Biteau, S.G. Blaess, A. Blanco, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, N. Borodai, A.M. Botti, J. Brack, T. Bretz, A. Bridgeman, F.L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, K.S. Caballero-Mora, L. Caccianiga, L. Calcagni, A. Cancio, F. Canfora, J.M. Carceller, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, J.A. Chinellato, J. Chudoba, L. Chytka, R.W. Clay, A.C. Cobos Cerutti, R. Colalillo, A. Coleman, M.R. Coluccia, R. Conceição, A. Condorelli, G. Consolati, F. Contreras, F. Convenga, M.J. Cooper, S. Coutu, C.E. Covault, B. Daniel, S. Dasso, K. Daumiller, B.R. Dawson, J.A. Day, R.M. de Almeida, S.J. de Jong, G. De Mauro, J.R.T. de Mello Neto, I. De Mitri, J. de Oliveira, F.O. de Oliveira Salles, V. de Souza, J. Debatin, M. del Río, O. Deligny, N. Dhital, M.L. Díaz Castro, F. Diogo, C. Dobrigkeit, J.C. D'Olivo, Q. Dorosti, R.C. dos Anjos, M.T. Dova, A. Dundovic, J. Ebr, R. Engel, M. Erdmann, C.O. Escobar, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A.C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, L.P. Ferreyro, J.M. Figueira, A. Filipčič, M.M. Freire, T. Fujii, A. Fuster, B. García, H. Gemmeke, A. Gherghel-Lascu, P.L. Ghia, U. Giaccari, M. Giammarchi, M. Giller, D. Głas, J. Glombitza, F. Gobbi, G. Golup, M. Gómez Berisso, P.F. Gómez Vitale, J.P. Gongora, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T.D. Grubb, F. Guarino, G.P. Guedes, E. Guido, R. Halliday, M.R. Hampel, P. Hansen, D. Harari, T.A. Harrison, V.M. Harvey, A. Haungs, T. Hebbeker, D. Heck, P. Heimann, G.C. Hill, C. Hojvat, E.M. Holt, P. Homola, J.R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, J. Hulsman, A. Insolia, P.G. Isar, I. Jandt, J.A. Johnsen, M. Josebachuili, J. Jurysek, A. Kääpä, K.H. Kampert, B. Keilhauer, N. Kemmerich, J. Kemp, H.O. Klages, M. Kleifges, J. Kleinfeller, R. Krause, D. Kuempel, G. Kukec Mezek, A. Kuotb Awad, B.L. Lago, D. LaHurd, R.G. Lang, R. Legumina, M.A. Leigui de Oliveira, V. Lenok, A. Letessier-Selvon, I. Lhenry-Yvon, O.C. Lippmann, D. Lo Presti, L. Lopes, R. López, A. López Casado, R. Lorek, Q. Luce, A. Lucero, M. Malacari, G. Mancarella, D. Mandat, B.C. Manning, P. Mantsch, A.G. Mariazzi, I.C. Mariş, G. Marsella, D. Martello, H. Martinez, O. Martínez Bravo, M. Mastrodicasa, H.J. Mathes, S. Mathys, J. Matthews, G. Matthiae, E. Mayotte, P.O. Mazur, G. Medina-Tanco, D. Melo, A. Menshikov, K.-D. Merenda, S. Michal, M.I. Micheletti, L. Middendorf, L. Miramonti, B. Mitrica, D. Mockler, S. Mollerach, F. Montanet, C. Morello, G. Morlino, M. Mostafá, A.L. Müller, M.A. Muller, S. Müller, R. Mussa, L. Nellen, P.H. Nguyen, M. Niculescu-Oglinzanu, M. Niechciol, D. Nitz, D. Nosek, V. Novotny, L. Nožka, A Nucita, L.A. Núñez, F. Oikonomou, A. Olinto, M. Palatka, J. Pallotta, M.P. Panetta, P. Papenbreer, G. Parente, A. Parra, M. Pech, F. Pedreira, J. Pȩkala, R. Pelayo, J. Peña-Rodriguez, L.A.S. Pereira, M. Perlin, L. Perrone, C. Peters, S. Petrera, J. Phuntsok, T. Pierog, M. Pimenta, V. Pirronello, M. Platino, J. Poh, B. Pont, C. Porowski, R.R. Prado, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, S. Quinn, R. Ramos-Pollan, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, P. Ristori, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M.J. Roncoroni, M. Roth, E. Roulet, A.C. Rovero, P. Ruehl, S.J. Saffi, A. Saftoiu, F. Salamida, H. Salazar, G. Salina, J.D. Sanabria Gomez, F. Sánchez, E.M. Santos, E. Santos, F. Sarazin, R. Sarmento, C. Sarmiento-Cano, R. Sato, P. Savina, M. Schauer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, P. Schovánek, F.G. Schröder, S. Schröder, J. Schumacher, S.J. Sciutto, M. Scornavacche, R.C. Shellard, G. Sigl, G. Silli, O. Sima, R. Šmída, G.R. Snow, P. Sommers, J.F. Soriano, J. Souchard, R. Squartini, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, M. Stolpovskiy, A. Streich, F. Suarez, M. Suárez-Durán, T. Sudholz, T. Suomijärvi, A.D. Supanitsky, J. Šupík, Z. Szadkowski, A. Taboada, O.A. Taborda, A. Tapia, C. Timmermans, C.J. Todero Peixoto, B. Tomé, G. Torralba Elipe, A. Travaini, P. Travnicek, M. Trini, M. Tueros, R. Ulrich, M. Unger, M. Urban, J.F. Valdés Galicia, I. Valiño, L. Valore, P. van Bodegom, A.M. van den Berg, A. van Vliet, E. Varela, B. Vargas Cárdenas, D. Veberič, C. Ventura, I.D. Vergara Quispe, V. Verzi, J. Vicha, L. Villaseñor, J. Vink, S. Vorobiov, H. Wahlberg, A.A. Watson, M. Weber, A. Weindl, M. Wiedeński, L. Wiencke, H. Wilczyński, T. Winchen, M. Wirtz, D. Wittkowski, B. Wundheiler, L. Yang, A. Yushkov, E. Zas, D. Zavrtanik, M. Zavrtanik, L. Zehrer, A. Zepeda, B. Zimmermann, M. Ziolkowski, Z. Zong, and F. Zuccarello

Subjects
UHECR, high energy neutrinos, high energy photons, high energy neutrons, multi-messenger astrophysics, compact binary mergers, Astronomy, QB1-991, Geophysics. Cosmic physics, QC801-809
Abstract

An overview of the multi-messenger capabilities of the Pierre Auger Observatory is presented. The techniques and performance of searching for Ultra-High Energy neutrinos, photons and neutrons are described. Some of the most relevant results are reviewed, such as stringent upper bounds that were placed to a flux of diffuse cosmogenic neutrinos and photons, bounds placed on neutrinos emitted from compact binary mergers that were detected by LIGO and Virgo during their first and second observing runs, as well as searches for high energy photons and neutrons from the Galactic center that constrain the properties of the putative Galactic PeVatron, observed by the H.E.S.S. collaboration. The observation of directional correlations between ultra-high energy cosmic rays and either high energy astrophysical neutrinos or specific source populations, weighted by their electromagnetic radiation, are also discussed. They constitute additional multi-messenger approaches aimed at identifying the sources of high energy cosmic rays.

Published
2019
Full Text
View/download PDF

15. Expansion of the distribution range of angiosperm species for the states of Maranhão and Tocantins, Brazil, through a territorial action plan

Author

Lucas C. Marinho, André V. Scatigna, Amanda L. Garcia, Ellen Thamara S. Castro, Gabriela Amorim, Fabio A. Silva, Jone Clebson R. Mendes, Karena M. Pimenta, Natércia Camille V. Feitosa, and Alessandro W.C. Ferreira

Subjects
Cerrado, new records, Pró-espécies, seed plants, Biology (General), QH301-705.5
Abstract

We expand the geographical distribution of 10 angiosperm species in Maranhão and Tocantins states. The species were collected during two field expeditions carried out by the Territorial Action Plan for the conservation of endangered species of the Meio Norte Territory between September 20 and 30, 2022 and between July 24 and 30, 2023, in both states. Photographs, comments on morphology and distribution-al data are provided for species of Acanthaceae, Aristolochiaceae, Euphorbiaceae, Myrtaceae, Orchidace-ae, Plantaginaceae, Pontederiaceae and Turneraceae.

Published
2024
Full Text
View/download PDF

16. Evidence for a mixed mass composition at the ‘ankle’ in the cosmic-ray spectrum

Author

A. Aab, P. Abreu, M. Aglietta, E.J. Ahn, I. Al Samarai, I.F.M. Albuquerque, I. Allekotte, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, M. Ambrosio, G.A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, F. Arqueros, N. Arsene, H. Asorey, P. Assis, J. Aublin, G. Avila, A.M. Badescu, A. Balaceanu, C. Baus, J.J. Beatty, K.H. Becker, J.A. Bellido, C. Berat, M.E. Bertaina, P.L. Biermann, P. Billoir, J. Biteau, S.G. Blaess, A. Blanco, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, N. Borodai, A.M. Botti, J. Brack, I. Brancus, T. Bretz, A. Bridgeman, F.L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, K.S. Caballero-Mora, B. Caccianiga, L. Caccianiga, A. Cancio, F. Canfora, L. Caramete, R. Caruso, A. Castellina, G. Cataldi, L. Cazon, R. Cester, A.G. Chavez, A. Chiavassa, J.A. Chinellato, J. Chudoba, R.W. Clay, R. Colalillo, A. Coleman, L. Collica, M.R. Coluccia, R. Conceição, F. Contreras, M.J. Cooper, S. Coutu, C.E. Covault, J. Cronin, R. Dallier, S. D'Amico, B. Daniel, S. Dasso, K. Daumiller, B.R. Dawson, R.M. de Almeida, S.J. de Jong, G. De Mauro, J.R.T. de Mello Neto, I. De Mitri, J. de Oliveira, V. de Souza, J. Debatin, L. del Peral, O. Deligny, C. Di Giulio, A. Di Matteo, M.L. Díaz Castro, F. Diogo, C. Dobrigkeit, J.C. D'Olivo, A. Dorofeev, R.C. dos Anjos, M.T. Dova, A. Dundovic, J. Ebr, R. Engel, M. Erdmann, M. Erfani, C.O. Escobar, J. Espadanal, A. Etchegoyen, H. Falcke, K. Fang, G. Farrar, A.C. Fauth, N. Fazzini, B. Fick, J.M. Figueira, A. Filevich, A. Filipčič, O. Fratu, M.M. Freire, T. Fujii, A. Fuster, B. García, D. Garcia-Pinto, F. Gaté, H. Gemmeke, A. Gherghel-Lascu, P.L. Ghia, U. Giaccari, M. Giammarchi, M. Giller, D. Głas, C. Glaser, H. Glass, G. Golup, M. Gómez Berisso, P.F. Gómez Vitale, N. González, B. Gookin, J. Gordon, A. Gorgi, P. Gorham, P. Gouffon, A.F. Grillo, T.D. Grubb, F. Guarino, G.P. Guedes, M.R. Hampel, P. Hansen, D. Harari, T.A. Harrison, J.L. Harton, Q. Hasankiadeh, A. Haungs, T. Hebbeker, D. Heck, P. Heimann, A.E. Herve, G.C. Hill, C. Hojvat, E. Holt, P. Homola, J.R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, J. Hulsman, A. Insolia, P.G. Isar, I. Jandt, S. Jansen, J.A. Johnsen, M. Josebachuili, A. Kääpä, O. Kambeitz, K.H. Kampert, P. Kasper, I. Katkov, B. Keilhauer, E. Kemp, R.M. Kieckhafer, H.O. Klages, M. Kleifges, J. Kleinfeller, R. Krause, N. Krohm, D. Kuempel, G. Kukec Mezek, N. Kunka, A. Kuotb Awad, D. LaHurd, L. Latronico, M. Lauscher, P. Lautridou, P. Lebrun, R. Legumina, M.A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, L. Lopes, R. López, A. López Casado, Q. Luce, A. Lucero, M. Malacari, M. Mallamaci, D. Mandat, P. Mantsch, A.G. Mariazzi, I.C. Mariş, G. Marsella, D. Martello, H. Martinez, O. Martínez Bravo, J.J. Masías Meza, H.J. Mathes, S. Mathys, J. Matthews, J.A.J. Matthews, G. Matthiae, E. Mayotte, P.O. Mazur, C. Medina, G. Medina-Tanco, D. Melo, A. Menshikov, S. Messina, M.I. Micheletti, L. Middendorf, I.A. Minaya, L. Miramonti, B. Mitrica, D. Mockler, L. Molina-Bueno, S. Mollerach, F. Montanet, C. Morello, M. Mostafá, G. Müller, M.A. Muller, S. Müller, I. Naranjo, S. Navas, L. Nellen, J. Neuser, P.H. Nguyen, M. Niculescu-Oglinzanu, M. Niechciol, L. Niemietz, T. Niggemann, D. Nitz, D. Nosek, V. Novotny, H. Nožka, L.A. Núñez, L. Ochilo, F. Oikonomou, A. Olinto, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, P. Papenbreer, G. Parente, A. Parra, T. Paul, M. Pech, F. Pedreira, J. Pȩkala, R. Pelayo, J. Peña-Rodriguez, L.A.S. Pereira, L. Perrone, C. Peters, S. Petrera, J. Phuntsok, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, C. Porowski, R.R. Prado, P. Privitera, M. Prouza, E.J. Quel, S. Querchfeld, S. Quinn, R. Ramos-Pollant, J. Rautenberg, O. Ravel, D. Ravignani, D. Reinert, B. Revenu, J. Ridky, M. Risse, P. Ristori, V. Rizi, W. Rodrigues de Carvalho, G. Rodriguez Fernandez, J. Rodriguez Rojo, M.D. Rodríguez-Frías, D. Rogozin, J. Rosado, M. Roth, E. Roulet, A.C. Rovero, S.J. Saffi, A. Saftoiu, H. Salazar, A. Saleh, F. Salesa Greus, G. Salina, J.D. Sanabria Gomez, F. Sánchez, P. Sanchez-Lucas, E.M. Santos, E. Santos, F. Sarazin, B. Sarkar, R. Sarmento, C. Sarmiento-Cano, R. Sato, C. Scarso, M. Schauer, V. Scherini, H. Schieler, D. Schmidt, O. Scholten, P. Schovánek, F.G. Schröder, A. Schulz, J. Schulz, J. Schumacher, S.J. Sciutto, A. Segreto, M. Settimo, A. Shadkam, R.C. Shellard, G. Sigl, G. Silli, O. Sima, A. Śmiałkowski, R. Šmída, G.R. Snow, P. Sommers, S. Sonntag, J. Sorokin, R. Squartini, D. Stanca, S. Stanič, J. Stasielak, F. Strafella, F. Suarez, M. Suarez Durán, T. Sudholz, T. Suomijärvi, A.D. Supanitsky, M.S. Sutherland, J. Swain, Z. Szadkowski, O.A. Taborda, A. Tapia, A. Tepe, V.M. Theodoro, C. Timmermans, C.J. Todero Peixoto, L. Tomankova, B. Tomé, A. Tonachini, G. Torralba Elipe, D. Torres Machado, M. Torri, P. Travnicek, M. Trini, R. Ulrich, M. Unger, M. Urban, A. Valbuena-Delgado, J.F. Valdés Galicia, I. Valiño, L. Valore, G. van Aar, P. van Bodegom, A.M. van den Berg, A. van Vliet, E. Varela, B. Vargas Cárdenas, G. Varner, J.R. Vázquez, R.A. Vázquez, D. Veberič, V. Verzi, J. Vicha, L. Villaseñor, S. Vorobiov, H. Wahlberg, O. Wainberg, D. Walz, A.A. Watson, M. Weber, A. Weindl, L. Wiencke, H. Wilczyński, T. Winchen, D. Wittkowski, B. Wundheiler, S. Wykes, L. Yang, D. Yelos, P. Younk, A. Yushkov, E. Zas, D. Zavrtanik, M. Zavrtanik, A. Zepeda, B. Zimmermann, M. Ziolkowski, Z. Zong, and F. Zuccarello

Subjects
Physics, QC1-999
Abstract

We report a first measurement for ultrahigh energy cosmic rays of the correlation between the depth of shower maximum and the signal in the water Cherenkov stations of air-showers registered simultaneously by the fluorescence and the surface detectors of the Pierre Auger Observatory. Such a correlation measurement is a unique feature of a hybrid air-shower observatory with sensitivity to both the electromagnetic and muonic components. It allows an accurate determination of the spread of primary masses in the cosmic-ray flux. Up till now, constraints on the spread of primary masses have been dominated by systematic uncertainties. The present correlation measurement is not affected by systematics in the measurement of the depth of shower maximum or the signal in the water Cherenkov stations. The analysis relies on general characteristics of air showers and is thus robust also with respect to uncertainties in hadronic event generators. The observed correlation in the energy range around the ‘ankle’ at lg⁡(E/eV)=18.5–19.0 differs significantly from expectations for pure primary cosmic-ray compositions. A light composition made up of proton and helium only is equally inconsistent with observations. The data are explained well by a mixed composition including nuclei with mass A>4. Scenarios such as the proton dip model, with almost pure compositions, are thus disfavored as the sole explanation of the ultrahigh-energy cosmic-ray flux at Earth. Keywords: Pierre Auger Observatory, Cosmic rays, Mass composition, Ankle

Published
2016
Full Text
View/download PDF

17. Measurement of the electron structure function F2e at LEP energies

Author

J. Abdallah, P. Abreu, W. Adam, P. Adzic, T. Albrecht, R. Alemany-Fernandez, T. Allmendinger, P.P. Allport, U. Amaldi, N. Amapane, S. Amato, E. Anashkin, A. Andreazza, S. Andringa, N. Anjos, P. Antilogus, W-D. Apel, Y. Arnoud, S. Ask, B. Asman, J.E. Augustin, A. Augustinus, P. Baillon, A. Ballestrero, P. Bambade, R. Barbier, D. Bardin, G.J. Barker, A. Baroncelli, M. Battaglia, M. Baubillier, K-H. Becks, M. Begalli, A. Behrmann, K. Belous, E. Ben-Haim, N. Benekos, A. Benvenuti, C. Berat, M. Berggren, D. Bertrand, M. Besancon, N. Besson, D. Bloch, M. Blom, M. Bluj, M. Bonesini, M. Boonekamp, P.S.L. Booth, G. Borisov, O. Botner, B. Bouquet, T.J.V. Bowcock, I. Boyko, M. Bracko, R. Brenner, E. Brodet, P. Bruckman, J.M. Brunet, B. Buschbeck, P. Buschmann, M. Calvi, T. Camporesi, V. Canale, F. Carena, N. Castro, F. Cavallo, M. Chapkin, Ph. Charpentier, P. Checchia, R. Chierici, P. Chliapnikov, J. Chudoba, S.U. Chung, K. Cieslik, P. Collins, R. Contri, G. Cosme, F. Cossutti, M.J. Costa, D. Crennell, J. Cuevas, J. D'Hondt, T. da Silva, W. Da Silva, G. Della Ricca, A. De Angelis, W. De Boer, C. De Clercq, B. De Lotto, N. De Maria, A. De Min, L. de Paula, L. Di Ciaccio, A. Di Simone, K. Doroba, J. Drees, G. Eigen, T. Ekelof, M. Ellert, M. Elsing, M.C. Espirito Santo, G. Fanourakis, D. Fassouliotis, M. Feindt, J. Fernandez, A. Ferrer, F. Ferro, U. Flagmeyer, H. Foeth, E. Fokitis, F. Fulda-Quenzer, J. Fuster, M. Gandelman, C. Garcia, Ph. Gavillet, E. Gazis, R. Gokieli, B. Golob, G. Gomez-Ceballos, P. Gonçalves, E. Graziani, G. Grosdidier, K. Grzelak, J. Guy, C. Haag, A. Hallgren, K. Hamacher, K. Hamilton, S. Haug, F. Hauler, V. Hedberg, M. Hennecke, J. Hoffman, S-O. Holmgren, P.J. Holt, M.A. Houlden, J.N. Jackson, G. Jarlskog, P. Jarry, D. Jeans, E.K. Johansson, P. Jonsson, C. Joram, L. Jungermann, F. Kapusta, S. Katsanevas, E. Katsoufis, G. Kernel, B.P. Kersevan, U. Kerzel, B.T. King, N.J. Kjaer, P. Kluit, P. Kokkinias, C. Kourkoumelis, O. Kouznetsov, Z. Krumstein, M. Kucharczyk, J. Lamsa, G. Leder, F. Ledroit, L. Leinonen, R. Leitner, J. Lemonne, V. Lepeltier, T. Lesiak, W. Liebig, D. Liko, A. Lipniacka, J.H. Lopes, J.M. Lopez, D. Loukas, P. Lutz, L. Lyons, J. MacNaughton, A. Malek, S. Maltezos, F. Mandl, J. Marco, R. Marco, B. Marechal, M. Margoni, J-C. Marin, C. Mariotti, A. Markou, C. Martinez-Rivero, J. Masik, N. Mastroyiannopoulos, F. Matorras, C. Matteuzzi, F. Mazzucato, M. Mazzucato, R. Mc Nulty, C. Meroni, E. Migliore, W. Mitaroff, U. Mjoernmark, T. Moa, M. Moch, K. Moenig, R. Monge, J. Montenegro, D. Moraes, S. Moreno, P. Morettini, U. Mueller, K. Muenich, M. Mulders, L. Mundim, W. Murray, B. Muryn, G. Myatt, T. Myklebust, M. Nassiakou, F. Navarria, K. Nawrocki, S. Nemecek, R. Nicolaidou, M. Nikolenko, A. Oblakowska-Mucha, V. Obraztsov, A. Olshevski, A. Onofre, R. Orava, K. Osterberg, A. Ouraou, A. Oyanguren, M. Paganoni, S. Paiano, J.P. Palacios, H. Palka, Th.D. Papadopoulou, L. Pape, C. Parkes, F. Parodi, U. Parzefall, A. Passeri, O. Passon, L. Peralta, V. Perepelitsa, A. Perrotta, A. Petrolini, J. Piedra, L. Pieri, F. Pierre, M. Pimenta, E. Piotto, T. Podobnik, V. Poireau, M.E. Pol, G. Polok, V. Pozdniakov, N. Pukhaeva, A. Pullia, D. Radojicic, P. Rebecchi, J. Rehn, D. Reid, R. Reinhardt, P. Renton, F. Richard, J. Ridky, M. Rivero, D. Rodriguez, A. Romero, P. Ronchese, P. Roudeau, T. Rovelli, V. Ruhlmann-Kleider, D. Ryabtchikov, A. Sadovsky, L. Salmi, J. Salt, C. Sander, A. Savoy-Navarro, U. Schwickerath, R. Sekulin, M. Siebel, A. Sisakian, W. Slominski, G. Smadja, O. Smirnova, A. Sokolov, A. Sopczak, R. Sosnowski, T. Spassov, M. Stanitzki, A. Stocchi, J. Strauss, B. Stugu, M. Szczekowski, M. Szeptycka, T. Szumlak, J. Szwed, T. Tabarelli, F. Tegenfeldt, J. Timmermans, L. Tkatchev, M. Tobin, S. Todorovova, B. Tomé, A. Tonazzo, P. Tortosa, P. Travnicek, D. Treille, G. Tristram, M. Trochimczuk, C. Troncon, M-L. Turluer, I.A. Tyapkin, P. Tyapkin, S. Tzamarias, V. Uvarov, G. Valenti, P. Van Dam, J. Van Eldik, N. van Remortel, I. Van Vulpen, G. Vegni, F. Veloso, W. Venus, P. Verdier, V. Verzi, D. Vilanova, L. Vitale, V. Vrba, H. Wahlen, A.J. Washbrook, C. Weiser, D. Wicke, J. Wickens, G. Wilkinson, M. Winter, M. Witek, O. Yushchenko, A. Zalewska, P. Zalewski, D. Zavrtanik, V. Zhuravlov, N.I. Zimin, A. Zintchenko, and M. Zupan

Subjects
Physics, QC1-999
Abstract

The hadronic part of the electron structure function F2e has been measured for the first time, using e+e− data collected by the DELPHI experiment at LEP, at centre-of-mass energies of s=91.2–209.5 GeV. The data analysis is simpler than that of the measurement of the photon structure function. The electron structure function F2e data are compared to predictions of phenomenological models based on the photon structure function. It is shown that the contribution of large target photon virtualities is significant. The data presented can serve as a cross-check of the photon structure function F2γ analyses and help in refining existing parameterisations.

Published
2014
Full Text
View/download PDF

18. Estimativa de consumo de matéria seca e de fibra em detergente neutro por vacas leiteiras sob pastejo, suplementadas com diferentes quantidades de alimento concentrado Estimation of dry matter and neutral detergent fiber intake by grazing dairy cows supplemented with different amounts of concentrate

Author

B.M. Sousa, H.M. Saturnino, A.L.C.C. Borges, F.C.F. Lopes, R.R. Silva, M.M. Campos, M. Pimenta, and W.E. Campos

Subjects
bovino, Brachiaria, consumo, suplementação, dairy cow, intake, supplementation, Animal culture, SF1-1100
Abstract

Estimou-se o consumo de matéria seca e de fibra em detergente neutro por vacas leiteiras mestiças em pastejo de gramíneas do gênero Brachiaria. Foram utilizadas 24 vacas em lactação, distribuídas em três tratamentos com oito vacas cada, suplementadas com 4, 6 ou 8kg de matéria natural de alimento concentrado/vaca/dia, no momento da ordenha, duas vezes ao dia. O delineamento utilizado foi o de blocos ao acaso, sendo oito blocos com três vacas em cada um, cada vaca sendo alimentada com um dos três tratamentos. O consumo de fibra em detergente neutro da gramínea foi de 1,1, 1,0 e 1,2%/peso vivo naquelas vacas suplementadas com 4, 6 e 8kg/vaca/dia, respectivamente, sendo o tratamento com a maior quantidade de suplemento diferente dos demais (PThe intakes of dry matter and neutral detergent fiber (NDF) by crossbred lactating cows were estimated under Brachiaria grazing. Twenty-four cows were allotted in three treatments in order to receive 4, 6, or 8kg of concentrate twice a day, during the milking. The experiment was designed in randomized blocks, being eight blocks with three cows in each. The intake of NDF was 1.1, 1.0, and 1.2 of live weight for cows fed 4, 6, and 8kg of concentrate per day, respectively. The 8kg concentrate treatment produced different results (P

Published
2008
Full Text
View/download PDF

19. Ultrahigh Energy Neutrinos at the Pierre Auger Observatory

Author

P. Abreu, M. Aglietta, M. Ahlers, E. J. Ahn, I. F. M. Albuquerque, D. Allard, I. Allekotte, J. Allen, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, R. Alves Batista, M. Ambrosio, A. Aminaei, L. Anchordoqui, S. Andringa, T. Antičić, C. Aramo, E. Arganda, F. Arqueros, H. Asorey, P. Assis, J. Aublin, M. Ave, M. Avenier, G. Avila, T. Bäcker, A. M. Badescu, M. Balzer, K. B. Barber, A. F. Barbosa, R. Bardenet, S. L. C. Barroso, B. Baughman, J. Bäuml, J. J. Beatty, B. R. Becker, K. H. Becker, A. Bellétoile, J. A. Bellido, S. BenZvi, C. Berat, X. Bertou, P. L. Biermann, P. Billoir, F. Blanco, M. Blanco, C. Bleve, H. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, R. Bonino, N. Borodai, J. Brack, I. Brancus, P. Brogueira, W. C. Brown, R. Bruijn, P. Buchholz, A. Bueno, R. E. Burton, K. S. Caballero-Mora, B. Caccianiga, L. Caramete, R. Caruso, A. Castellina, O. Catalano, G. Cataldi, L. Cazon, R. Cester, J. Chauvin, S. H. Cheng, A. Chiavassa, J. A. Chinellato, J. Chirinos Diaz, J. Chudoba, M. Cilmo, R. W. Clay, M. R. Coluccia, R. Conceição, F. Contreras, H. Cook, M. J. Cooper, J. Coppens, A. Cordier, S. Coutu, C. E. Covault, A. Creusot, A. Criss, J. Cronin, A. Curutiu, S. Dagoret-Campagne, R. Dallier, B. Daniel, S. Dasso, K. Daumiller, B. R. Dawson, R. M. de Almeida, M. De Domenico, C. De Donato, S. J. de Jong, G. De La Vega, W. J. M. de Mello Junior, J. R. T. de Mello Neto, I. De Mitri, V. de Souza, K. D. de Vries, L. del Peral, M. del Río, O. Deligny, H. Dembinski, N. Dhital, C. Di Giulio, M. L. Díaz Castro, P. N. Diep, F. Diogo, C. Dobrigkeit, W. Docters, J. C. D'Olivo, P. N. Dong, A. Dorofeev, J. C. dos Anjos, M. T. Dova, D. D'Urso, I. Dutan, J. Ebr, R. Engel, M. Erdmann, C. O. Escobar, J. Espadanal, A. Etchegoyen, P. Facal San Luis, H. Falcke, G. Farrar, A. C. Fauth, N. Fazzini, A. P. Ferguson, B. Fick, A. Filevich, A. Filipčič, S. Fliescher, C. E. Fracchiolla, E. D. Fraenkel, O. Fratu, U. Fröhlich, B. Fuchs, R. Gaior, R. F. Gamarra, S. Gambetta, B. García, S. T. Garcia Roca, D. Garcia-Gamez, D. Garcia-Pinto, A. Gascon Bravo, H. Gemmeke, P. L. Ghia, M. Giller, J. Gitto, H. Glass, M. S. Gold, G. Golup, F. Gomez Albarracin, M. Gómez Berisso, P. F. Gómez Vitale, P. Gonçalves, J. G. Gonzalez, B. Gookin, A. Gorgi, P. Gouffon, E. Grashorn, S. Grebe, N. Griffith, M. Grigat, A. F. Grillo, Y. Guardincerri, F. Guarino, G. P. Guedes, P. Hansen, D. Harari, T. A. Harrison, J. L. Harton, A. Haungs, T. Hebbeker, D. Heck, A. E. Herve, C. Hojvat, N. Hollon, V. C. Holmes, P. Homola, J. R. Hörandel, P. Horvath, M. Hrabovský, D. Huber, T. Huege, A. Insolia, F. Ionita, A. Italiano, C. Jarne, S. Jiraskova, M. Josebachuili, K. Kadija, K. H. Kampert, P. Karhan, P. Kasper, I. Katkov, B. Kégl, B. Keilhauer, A. Keivani, J. L. Kelley, E. Kemp, R. M. Kieckhafer, H. O. Klages, M. Kleifges, J. Kleinfeller, J. Knapp, D.-H. Koang, K. Kotera, N. Krohm, O. Krömer, D. Kruppke-Hansen, F. Kuehn, D. Kuempel, J. K. Kulbartz, N. Kunka, G. La Rosa, C. Lachaud, D. LaHurd, L. Latronico, R. Lauer, P. Lautridou, S. Le Coz, M. S. A. B. Leão, D. Lebrun, P. Lebrun, M. A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, R. López, A. Lopez Agüera, K. Louedec, J. Lozano Bahilo, L. Lu, A. Lucero, M. Ludwig, H. Lyberis, M. C. Maccarone, C. Macolino, S. Maldera, D. Mandat, P. Mantsch, A. G. Mariazzi, J. Marin, V. Marin, I. C. Maris, H. R. Marquez Falcon, G. Marsella, D. Martello, L. Martin, H. Martinez, O. Martínez Bravo, H. J. Mathes, J. Matthews, J. A. J. Matthews, G. Matthiae, D. Maurel, D. Maurizio, P. O. Mazur, G. Medina-Tanco, M. Melissas, D. Melo, E. Menichetti, A. Menshikov, P. Mertsch, C. Meurer, S. Mićanović, M. I. Micheletti, I. A. Minaya, L. Miramonti, L. Molina-Bueno, S. Mollerach, M. Monasor, D. Monnier Ragaigne, F. Montanet, B. Morales, C. Morello, E. Moreno, J. C. Moreno, M. Mostafá, C. A. Moura, M. A. Muller, G. Müller, M. Münchmeyer, R. Mussa, G. Navarra, J. L. Navarro, S. Navas, P. Necesal, L. Nellen, A. Nelles, J. Neuser, P. T. Nhung, M. Niechciol, L. Niemietz, N. Nierstenhoefer, D. Nitz, D. Nosek, L. Nožka, J. Oehlschläger, A. Olinto, M. Ortiz, N. Pacheco, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, N. Palmieri, G. Parente, E. Parizot, A. Parra, S. Pastor, T. Paul, M. Pech, J. Pękala, R. Pelayo, I. M. Pepe, L. Perrone, R. Pesce, E. Petermann, S. Petrera, A. Petrolini, Y. Petrov, C. Pfendner, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, V. H. Ponce, M. Pontz, A. Porcelli, P. Privitera, M. Prouza, E. J. Quel, S. Querchfeld, J. Rautenberg, O. Ravel, D. Ravignani, B. Revenu, J. Ridky, S. Riggi, M. Risse, P. Ristori, H. Rivera, V. Rizi, J. Roberts, W. Rodrigues de Carvalho, G. Rodriguez, I. Rodriguez Cabo, J. Rodriguez Martino, J. Rodriguez Rojo, M. D. Rodríguez-Frías, G. Ros, J. Rosado, T. Rossler, M. Roth, B. Rouillé-d'Orfeuil, E. Roulet, A. C. Rovero, C. Rühle, A. Saftoiu, F. Salamida, H. Salazar, F. Salesa Greus, G. Salina, F. Sánchez, C. E. Santo, E. Santos, E. M. Santos, F. Sarazin, B. Sarkar, S. Sarkar, R. Sato, N. Scharf, V. Scherini, H. Schieler, P. Schiffer, A. Schmidt, O. Scholten, H. Schoorlemmer, J. Schovancova, P. Schovánek, F. Schröder, S. Schulte, D. Schuster, S. J. Sciutto, M. Scuderi, A. Segreto, M. Settimo, A. Shadkam, R. C. Shellard, I. Sidelnik, G. Sigl, O. Sima, A. Śmiałkowski, R. Šmída, G. R. Snow, P. Sommers, J. Sorokin, H. Spinka, R. Squartini, Y. N. Srivastava, S. Stanic, J. Stapleton, J. Stasielak, M. Stephan, A. Stutz, F. Suarez, T. Suomijärvi, A. D. Supanitsky, T. Šuša, M. S. Sutherland, J. Swain, Z. Szadkowski, M. Szuba, A. Tapia, M. Tartare, O. Taşcău, R. Tcaciuc, N. T. Thao, D. Thomas, J. Tiffenberg, C. Timmermans, W. Tkaczyk, C. J. Todero Peixoto, G. Toma, L. Tomankova, B. Tomé, A. Tonachini, P. Travnicek, D. B. Tridapalli, G. Tristram, E. Trovato, M. Tueros, R. Ulrich, M. Unger, M. Urban, J. F. Valdés Galicia, I. Valiño, L. Valore, A. M. van den Berg, E. Varela, B. Vargas Cárdenas, J. R. Vázquez, R. A. Vázquez, D. Veberič, V. Verzi, J. Vicha, M. Videla, L. Villaseñor, H. Wahlberg, P. Wahrlich, O. Wainberg, D. Walz, A. A. Watson, M. Weber, K. Weidenhaupt, A. Weindl, F. Werner, S. Westerhoff, B. J. Whelan, A. Widom, G. Wieczorek, L. Wiencke, B. Wilczyñska, H. Wilczyñski, M. Will, C. Williams, T. Winchen, M. Wommer, B. Wundheiler, T. Yamamoto, T. Yapici, P. Younk, G. Yuan, A. Yushkov, B. Zamorano Garcia, E. Zas, D. Zavrtanik, M. Zavrtanik, I. Zaw, A. Zepeda, Y. Zhu, M. Zimbres Silva, and M. Ziolkowski

Subjects
Physics, QC1-999
Abstract

The observation of ultrahigh energy neutrinos (UHEνs) has become a priority in experimental astroparticle physics. UHEνs can be detected with a variety of techniques. In particular, neutrinos can interact in the atmosphere (downward-going ν) or in the Earth crust (Earth-skimming ν), producing air showers that can be observed with arrays of detectors at the ground. With the surface detector array of the Pierre Auger Observatory we can detect these types of cascades. The distinguishing signature for neutrino events is the presence of very inclined showers produced close to the ground (i.e., after having traversed a large amount of atmosphere). In this work we review the procedure and criteria established to search for UHEνs in the data collected with the ground array of the Pierre Auger Observatory. This includes Earth-skimming as well as downward-going neutrinos. No neutrino candidates have been found, which allows us to place competitive limits to the diffuse flux of UHEνs in the EeV range and above.

Published
2013
Full Text
View/download PDF

20. Lifetime Impact Study for Achondroplasia (LISA): Findings from an observational and multinational study focused on health-related quality of life in individuals with achondroplasia in Latin America

Author

Juan Llerena, Jr, Pablo Rosselli, Amanda Aragão, Cristina Valenzuela, Debora Bertola, Yaneth Mendez, Mariana del Pino, Nicolette Calvacanti, Paula Thomazinho, Jeanne M. Pimenta, Shelda Cohen, Tom Butt, José C. Thomaz, Jr, Renée Shediac, Richard Rowell, Tatiana S.P.C. Magalhães, Chong Kim, and Virginia Fano

Subjects
Achondroplasia, Disease burden, Health-related quality of life, Health care resource use, Skeletal dysplasia, Genetics, QH426-470, Medicine
Abstract

Purpose: The multisystem clinical manifestations and complications of achondroplasia, the most common form of disproportionate short stature, can cause functional impairment and psychosocial burden. The Lifetime Impact Study for Achondroplasia (LISA), aimed to assess health-related quality of life and medical resource utilization among Latin America patients with achondroplasia. Methods: Data were collected from individuals aged 3 years and above in Argentina, Brazil, and Colombia between 2018 and 2021. A total of 172 patients participated in the study. Results: Children with achondroplasia reported lower scores compared with average stature children in Quality of Life in Short Stature Youth (QoLISSY) and Pediatric Quality of Life Inventory (PedsQL) questionnaires, with the greatest impact on physical and social domains. Among adolescents, a significant percentage reported pain, 10.3% experienced pain in 3 or more sites. Adults scored lower than the reference population in the EQ-5D-5L Visual Analog Score, and a considerable portion reported moderate to severe anxiety/depression, pain or discomfort, and mobility problems. The Nottingham Health Profile (NHP) revealed poor health status in terms of energy, pain, and mobility. Medical events, particularly musculoskeletal and connective tissue disorders were reported, resulting in high medical resource utilization. Conclusion: Overall, the Lifetime Impact Study for Achondroplasia study provides extensive data on health-related quality of life, psychosocial impact, and health care resource utilization among individuals with achondroplasia in Latin America. The findings confirm a significant burden of illness across multiple domains for these individuals.

Published
2024
Full Text
View/download PDF

22. Um método de verificação de conformidade do plantio realizado no contexto do Seguro Rural no Brasil com Zoneamento Agrícola de Risco Climático (ZARC).

Author

Weber S. Pinto, Marconi de A. Pereira, José R. A. Júnior, Filipe Santos, Gustavo E. Marcatti, Pedro A. A. Silva, André Hirsch, Andréa C. R. Santos, Ivair Gomes, Fernando M. Pimenta, Glauciana M. Ataíde, Gabriel Pereira, Renato V. O. Castro, Marcela C. Ferreira, Leonardo B. Prado, Fernando A. Teixeira, and Daniel C. Pinheiro

Published
2022

23. Survival and preference of cotton boll weevil adults for alternative food sources

Author

M. Pimenta, R. A. Mata, M. Venzon, D. N. C. Cunha, E. M. G. Fontes, C. S. S. Pires, and E. R. Sujii

Subjects
Anthonomus grandis, Malvacea, okra, hibiscus, Science, Biology (General), QH301-705.5, Zoology, QL1-991, Botany, QK1-989
Abstract

Abstract Plants that have potential as alternative food source (floral nectar, pollen and plant tissues) to the boll weevil during the intercropping season were evaluated considering the prevalent conditions of Cerrado in the Central Brazil. Initially, we tested the nutritional adequacy for the survival of the insect of flower resource (pollen and nectar) provided by eight plant species (fennel, mexican sunflower, castor bean, okra, hibiscus, sorghum, pigeonpea and sunn hemp). Subsequently, we tested if the resources provided by the selected plants continued to be exploited by the boll weevil in the presence of cotton plant, its main food source average longevity of boll weevil adults was significantly longer when they were fed on hibiscus’ flowers (166.6 ± 74.4) and okra flowers (34.7 ± 28.9) than when they fed on flowers of other six species. Subsequently, the preference of the boll weevil in the use of resources was compared between okra or hibiscus and cotton plants, in dual choice experiments. Boll weevils preferred plants of the three species in the reproductive stages than those in vegetative stages. Although the cotton plant in the reproductive stage was the most preferred plant of all, boll weevils preferred flowering okra and hibiscus than cotton at the vegetative stage.

Full Text
View/download PDF

24. Avaliação do Composto Gerado no Aterro Sanitário do Município de Goiânia-GO e Sua Aplicabilidade

Author

Amanda R. S. Silva, Sandro M. Pimenta, and Tiago G. Ribeiro

Subjects
General Engineering
Abstract

Foi avaliada as características do composto gerado no aterro sanitário do município de Goiânia - GO e sua aplicabilidade. Realizaram-se coletas de amostras do composto, para determinações dos seguintes parâmetros: nitrogênio, fósforo e potássio (macronutrientes). Com os resultados, se estabeleceu a aplicabilidade do composto nas mudas do viveiro localizado no aterro, que são encaminhadas para os canteiros e praças do município de Goiânia. Apesar dos problemas operacionais, como falta de maquinário, recursos e mão de obra, terem refletido nas características dos parâmetros avaliados, o composto gerado apresentou caráter satisfatório e eficácia em sua aplicabilidade.

Published
2023

33. Extending the data collection from a clinical trial: The Extended Salford Lung Study research cohort

Author

Wilhelmine Meeraus, Qinggong Fu, George Mu, Mark Fry, Lucy Frith, and Jeanne M. Pimenta

Subjects
Pulmonary and Respiratory Medicine, Public Health, Environmental and Occupational Health
Abstract

The Extended Salford Lung Study (Ext-SLS) is an extension of the Salford Lung Studies (SLS) in asthma and chronic obstructive pulmonary disease (COPD) through retrospective and prospective collection of patient-level electronic health record (EHR) data. We compared the Ext-SLS cohort with the SLS intention-to-treat populations using descriptive analyses to determine if the strengths (e.g. randomization) of the clinical trial were maintained in the new cohort. Historical and patient-reported outcome data were captured from asthma-/COPD-specific questionnaires (e.g., Asthma Control Test [ACT]/COPD Assessment Test [CAT]). The Ext-SLS included 1147 participants (n = 798, SLS asthma; n = 349, SLS COPD). Of participants answering the ACT, 39% scored

Published
2023

34. Compartilhamento e abertura de dados na Ciência Aberta e a pesquisa em saúde pública na Lei Geral de Proteção de Dados

Author

Mauricio L. Barreto, Denise M. Pimenta, and Bethânia de A. Almeida

Abstract

O conhecimento científico é fundamentado em registros de observações e experimentações, que são organizados e interpretados a partir de teorias e métodos próprios das várias áreas do conhecimento. Os dados precisam ser apresentados de maneira coerente para corroborar os achados, que são validados ou refutados por pares. Com o advento do Big Data e do movimento da Ciência Aberta, esforços para disseminar e reutilizar dados de distintas fontes ganharam força. Neste contexto, emergem questionamentos éticos, legais e analíticos em torno dos usos e reusos de dados, particularmente de dados pessoais. Estes são tradicionalmente utilizados por pesquisas científicas que envolvem seres humanos, como os estudos conduzidos na área da saúde, que necessitam de aprovação do Sistema CEP/Conep (Comitê de Ética em Pesquisa/Comissão Nacional de Ética em Pesquisa) para averiguar a aderência das atividades propostas aos princípios éticos e normativos com o intuito de proteger os direitos dos participantes da pesquisa. Em virtude da crescente produção e reutilização de dados nos diversos setores da sociedade e das lacunas regulatórias para proteger os direitos dos titulares destas informações, no Brasil, a Lei Geral de Proteção de Dados (LGPD) foi aprovada e sancionada em 2018,passando a vigorar a partir de agosto de 2020. Considerando que dados circulam e que são utilizados por uma ampla gama de atores com interesses distintos e para finalidades diversas, o presente artigo terá por foco refletir sobre o compartilhamento e abertura de dados para pesquisa científica na perspectiva da Ciência Aberta como também as especificidades da pesquisa científica e da saúde pública no âmbito da LGPD. Palavras-chave: Compartilhamento e abertura de dados. Pesquisa científica. Saúde pública. LGPD.

Published
2021

35. Fatal infection caused by Cytauxzoon felis in a captive-reared jaguar (Panthera onca)

Author

Rodrigo Leite Soares, Carlos A R Nascimento, Jessica Teles Echeverria, Carolina C. Guizelini, Thyara de Deco-Souza, Felipe C B Esteves, Danilo Carloto Gomes, and Marcela M Pimenta

Subjects
Pathology, medicine.medical_specialty, Jaguar, Spleen, Wild animals, Article, biology.animal, medicine, CATS, biology, Felis, Panthera onca, Cytauxzoonosis, Piroplasms, biology.organism_classification, Cytauxzoon, Infectious Diseases, medicine.anatomical_structure, PCR, QL1-991, Felids, Animal Science and Zoology, Parasitology, Zoology
Abstract

Fatal infections with Cytauxzoon felis are common in domestic cats, and jaguars (Panthera onca) are believed carriers of this protozoan. Fatal C. felis infections have never been described in jaguars before. Thus, this study describes such an infection in a 5-month-old captive-reared jaguar that presented hyporexia and died at 26 days after the first clinical signs. During necropsy, samples were taken from several tissues, some were fixed in 10% formalin and process for histopathological diagnosis, and some samples were used for DNA extraction, amplification via PCR and sequencing of the potential pathogens. Grossly, marked splenomegaly and icterus were observed. Histologically, numerous structures that are morphologically compatible with Cytauxzoon spp. schizonts obliterated multiple blood vessels in the brain, leptomeninges, spinal cord, lungs, heart, skeletal muscle, adrenal gland, kidneys, spleen, small intestine and pancreas. C. felis was identified by PCR in many organs. Thus, C. felis infection in jaguars can be fatal, and the clinicopathological findings are similar to those of cytauxzoonosis in other wild and domestic felid species., Graphical abstract Image 1, Highlights • Cytauxzoon felis causes fatal infection in jaguar (Panthera onca). • Clinicopathological findings are similar to the infection in other felids. • Cytauxzoonosis should be investigated in young jaguars with jaundice.

Published
2021

36. Brazilian version of the OSTRC Questionnaire on health problems (OSTRC-BR): translation, cross-cultural adaptation and measurement properties

Author

Rafael M. Pimenta, Alexandre Dias Lopes, Luiz Hespanhol, VU University medical center, and AMS - Sports

Subjects
Cross-Cultural Comparison, medicine.medical_specialty, Psychometrics, medicine.medical_treatment, Physical Therapy, Sports Therapy and Rehabilitation, Correlation, Cronbach's alpha, Surveys and Questionnaires, medicine, Humans, Translations, Orthopedics and Sports Medicine, Reliability (statistics), Original Research, Rehabilitation, biology, Receiver operating characteristic, Athletes, Reproducibility of Results, Intra-rater reliability, biology.organism_classification, Test (assessment), Physical therapy, Psychology, Brazil
Abstract

Background The Oslo Sports Trauma Research Center - Questionnaire on Health Problems (OSTRC-QHP) has been shown to be a valid and reliable questionnaire for monitoring athletes with acute, overuse, and illness problems. Objectives To translate and cross-culturally adapt the OSTRC-QHP into Brazilian-Portuguese (OSTRC-BR), and investigate the measurement properties of this version. Methods The original (Norwegian) questionnaire was translated and culturally adapted following existing guidelines. Measurement properties of the OSTRC-BR were investigated in 134 athletes followed for 13 weeks. Reliability was analyzed via internal consistency and test-retest reliability. Responsiveness was assessed by effect size (ES) estimations, correlation of the OSTRC-BR severity score with the Global Perceived Effect scale (GPE) and the Numeric Pain Rating Scale (NPRS), and by the Receiver Operating Characteristic (ROC) Curve test based on the area under the curve (AUC). Results The OSTRC-QHP has been translated and cross-culturally adapted successfully. The Cronbach's alpha was 0.93 (95% CI: 0.92, 0.94). Intrarater reliability (ICC2,1) of 0.96 (95% CI: 0.94, 0.98) was classified as excellent. ES estimation showed large effects (1.14 to 1.39). OSTRC-BR correlation was moderate (0.58 to 0.72) with the GPE and substantial (0.84 to 0.89) with the NPRS. The AUC values were above 0.70 when analysing all types of health problems. Conclusions The OSTRC-BR presented adequate measurement properties. The OSTRC-BR is a valid, reliable, responsive, and, therefore, an adequate tool for monitoring Brazilian athletes from different sports during training and competitions.

Published
2021

37. Performance Evaluation of LIDAR and SODAR Wind Profilers on the Brazilian Equatorial Margin

Author

Audalio R. Torres Junior, Natália P. Saraiva, Arcilan T. Assireu, Francisco L. A. Neto, Felipe M. Pimenta, Ramon M. de Freitas, Osvaldo R. Saavedra, Clóvis B. M. Oliveira, Denivaldo C. P. Lopes, Shigeaki L. de Lima, Rafael B. S. Veras, and Denisson Q. Oliveira

Subjects
wind potential, equatorial margin, LIDAR, SODAR, Renewable Energy, Sustainability and the Environment, Geography, Planning and Development, Building and Construction, Management, Monitoring, Policy and Law
Abstract

This article seeks to compare the performance of a LIDAR Windcube V2, manufactured by Leosphere, with that of a SODAR MFAS, manufactured by Scintec, in evaluating wind speed at different altitudes. The data from these two sensors were collected at three locations on the Brazilian equatorial margin in the state of Maranhão. The comparison of these sensors aims at their simultaneous use at different points. The horizontal velocity components, by altitude, showed Pearson correlation values above 0.9 and values for the vertical velocity component between 0.7 and 0.85. As for the sampling efficiency, the LIDAR had a performance slightly higher than that of SODAR, especially at the point closest to the coast. In general, both sensors showed similar values, despite the differences in sampling methods. The results showed that the joint performance of these sensors had good correlation, being reliable for application in estimating wind potential for power generation in coastal areas of the equatorial region.

Published
2022
Full Text
View/download PDF

38. Recording the Learners’ Experience and Personalizing of Teaching with Serious Games in Virtual Reality

Author

Paula C. Fernandes, Arilton J. D. A. Nunes, Koda G. F. Melo, André S. G. M. Pimenta, Mariana Rezende, Claudia Martins Carneiro, and Saul Delabrida

Abstract

Jogos Sérios Imersivos são ferramentas úteis e eficazes para prover experiência para aprendizes. Nesses ambientes, são capazes de monitorar as práticas e experiências dos aprendizes rumo a personalização do aprendizado. Este trabalho criou uma abordagem educacional imersiva para que os professores recebam informações analíticas, tomem decisões sobre os melhores caminhos de aprendizagem e forneçam ensino personalizado. Apesar de estar em fase inicial, é possível visualizar o potencial de permitir: (i) feedback do perfil dos alunos por meio da análise de dados; (ii) quantidade de informações de um indivíduo ou de um grupo de indivíduos. O resultado deste trabalho é uma aula 3D em um laboratório de biologia em uma plataforma de realidade virtual, integrada a uma plataforma para gestão de ensino e registro das ações dos indivíduos.

Published
2022

39. Key Learnings from Running an Extension Study to a Real-World Effectiveness Trial: The Extended Salford Lung Study

Author

Wilhelmine Meeraus, Mark Fry, Sheila McCorkindale, Jamila Astrom, Alan Barth, David Leather, Rupert Jones, Richard Yeatman, and Jeanne M. Pimenta

Subjects
medicine.medical_specialty, Disease, Running, Primary care research, Secondary care, Pulmonary Disease, Chronic Obstructive, chemistry.chemical_compound, medicine, COPD, Humans, Pharmacology (medical), In patient, Prospective Studies, Patient participation, Lung, Original Research, Retrospective Studies, Real-world evidence, integumentary system, business.industry, Design information, Extension study, General Medicine, Asthma, chemistry, Family medicine, Vilanterol, EHR studies, Consent Forms, business
Abstract

Introduction The Salford Lung Studies (SLS) were real-world randomised controlled trials set within UK primary care that assessed the effectiveness and safety of initiating once-daily fluticasone furoate/vilanterol versus continuing usual care in patients with chronic obstructive pulmonary disease or asthma. Data were collected for a relatively short period, limiting the study of long-term outcomes. To broaden the capture of SLS patients’ data, we undertook the Extended SLS (Ext-SLS), aiming to better understand the patient disease journey and the effects of treatment in a real-world setting, through collection of patient-level data. Here, we present study design information and the challenges and learnings gathered in creating the Ext-SLS. Methods The Ext-SLS was intended to augment the SLS by collecting retrospective and prospective (up to 10 years from consent) primary and secondary care electronic health record (EHR) data and patient questionnaires. After ethics approval, general practitioners (GPs) obtained consent from SLS patients remotely (mean 3.2 years post-SLS completion). To facilitate GPs identifying eligible patients, a novel EHR-based approach flagged SLS patients who were alive and registered with their original GP. An automated system sent consent forms/questionnaires to patients. Medical data were collected via EHRs; primary care data were extracted from GPs’ systems whilst secondary care data were sourced from the UK NHS. Results Of the 75 GP sites from the SLS, 35 (47%) declined Ext-SLS participation leaving 4158 potentially eligible patients; 1169 (28%) patients were excluded as GPs could not confirm them as SLS participants or due to incapacity. Of 2989 patients invited, 1189 (40%) consented. Conclusions Developing an EHR-based trial extension was achieved, with reasonable consent rates amongst invited patients. The resulting Ext-SLS is a unique and valuable research resource. Leveraging EHRs and technology reduced GP burden, facilitating participation. Initiation of extension studies prior to study close-out may help increase GP and patient participation. Supplementary Information The online version contains supplementary material available at 10.1007/s12325-021-01827-2.

Published
2021

40. Belimumab use during pregnancy: Interim results of the belimumab pregnancy registry

Author

Patricia Juliao, Keele Wurst, Jeanne M. Pimenta, Kim Gemzoe, Helain Landy, M. Anthony Moody, Hugh Tilson, Deborah Covington, Tammy Moore, Rebecca Marino, Jennifer Gilbride, Andrew Liu, Paige Meizlik, and Michelle Petri

Subjects
Embryology, Health, Toxicology and Mutagenesis, Pediatrics, Perinatology and Child Health, Toxicology, Developmental Biology
Abstract

Belimumab is approved for active, autoantibody-positive systemic lupus erythematosus (SLE) and lupus nephritis, but limited data exist regarding its use in pregnancy. The Belimumab Pregnancy Registry (BPR, GSK Study BEL114256; NCT01532310) was created to evaluate pregnancy and infant outcomes following belimumab exposure.Individuals with SLE exposed to belimumab from 4 months before and/or during pregnancy can enroll into the BPR. The primary outcome is major birth defects; secondary outcomes include miscarriages, stillbirths, elective termination, pre-term birth, neonatal death, small for gestational age, and adverse infant outcomes during the first year of life. Belimumab exposure timing, concomitant medications, and other potential confounding factors are also collected. Data up to March 8, 2021, are reported descriptively.From an expected sample size target of 500 prospective pregnancies with a known outcome, only 55 were enrolled in the study. Among these, two pregnancy losses and 53 pregnancies with a live birth outcome were reported. Ten of the 53 live birth pregnancies resulted in a major birth defect. Ten pregnancies were enrolled after the pregnancy outcome occurred and were examined retrospectively (four live births with no defects, four miscarriages, and two elective terminations). There was no indication or pattern of birth defects associated with belimumab.Low recruitment numbers for the BPR and incomplete information limit the conclusions regarding belimumab exposure during pregnancy. There was no pattern or common mechanism of birth defects associated with belimumab within the BPR data.

Published
2022

41. The influence of stigma and trust in young people seeking support for their own or a friend's symptoms : the role of threat appraisals

Author

Simon Hunter, Susan Rasmussen, and Sofia M. Pimenta

Subjects
BF, Life-span and Life-course Studies, Social Sciences (miscellaneous)
Abstract

Background Stigma and trust influence how adolescents seek support for mental illness, though it is unclear how these influence their decisions to approach a range of potential sources of support. Moreover, even less is known about the ways in which these issues are related when a friend discloses symptoms of mental illness. Objective The study’s aims were to understand the role of stigma, trust, and threat appraisals in adolescents’ support seeking when exposed to their own, or to a friend’s, symptoms of mental illness. Method A vignette-based study comparing reports of support (friends, parents, teachers, professionals, and online) was completed with reference to either (i) experiencing symptoms of mental illness or (ii) having a friend disclose these types of symptoms. Two hundred and fifty adolescents (M = 12.75 years) answered questions pertaining to stigma (public and self), trust levels, threat appraisals, and support seeking. Results When dealing with their own symptoms, threat accounted for 4.8 and 2.5% of the variance when seeking support from parents and professionals, respectively. Self-stigma accounted for 2.4% of variance when seeking support from parents and 0.8% of variance when seeking support from professionals. Trust moderated the association between threat and the use of online support. When responding to a friend’s disclosure, higher levels of public-stigma were associated with lower support seeking from friends, parents, and professionals. Conclusions This study showed a distinction in how adolescents deal with their own or a friend’s symptoms of mental illness, and what resources they choose to ask for support from. Self-stigma, threat, and trust levels were particularly relevant when experiencing their own symptoms, while dealing with a friend’s disclosure was related to levels of public-stigma.

Published
2022

43. A Social-Ecological Approach to Understanding Adolescent Sexting Behavior

Author

Sofia M. Pimenta, Inmaculada Marín-López, Lee Knifton, Simon C. Hunter, Stefania Pagani, Lindsey Munro, Jun Sung Hong, and Kirsten Russell

Subjects
Male, medicine.medical_specialty, Adolescent, Social connectedness, Sexual Behavior, education, BF, 050109 social psychology, Constructive, Peer Group, Developmental psychology, Arts and Humanities (miscellaneous), Ecological psychology, medicine, Mainstream, Humans, 0501 psychology and cognitive sciences, Romantic-pressure, Peer pressure, General Psychology, Original Paper, Text Messaging, Schools, Parenting, Public health, 05 social sciences, Sexting, Peer-pressure, Sexual behavior, Adolescent Behavior, Female, School connectedness, Psychology, 050104 developmental & child psychology
Abstract

This study examined the extent to which active and passive sexting behaviors are associated with family-, school-, peer-, and romantic-level variables. Young people (N = 3,322; 49.1% female, 48.3% male, 2.6% other) aged 11 to 15 years old (M = 12.84, SD = 0.89) took part, and all attended mainstream secondary schools in Scotland. Participants completed self-report measures of school connectedness, parental love and support, perceived susceptibility to peer- and romantic-pressure (e.g., to display behaviors just to impress others), and their involvement in active and passive sexting. The importance of both school- and family-level factors was evident, though perceived romantic-pressure had the largest effect. However, neither school- nor family-level variables were moderated by either perceived romantic-pressure or perceived peer-pressure. Efforts to reduce sexting or increase its safety should primarily seek to tackle young people’s ability to respond effectively to romantic-pressure. It may also be helpful to develop school connectedness and to help families provide support that is constructive and not intrusive.

Published
2021

44. Selenium uptake and grain nutritional quality are affected by nitrogen fertilization in rice (Oryza sativa L.)

Author

Rafaela da Silva Arruda, Wagner L. Araújo, Rafael S. P. Malheiros, Fred A.L. Brito, Thaline M. Pimenta, Dimas M. Ribeiro, and Lubia S. Teixeira

Subjects
Oryza sativa, food and beverages, chemistry.chemical_element, Plant Science, General Medicine, Nutritional quality, Biology, Phosphate, Nitrogen, chemistry.chemical_compound, Nitrogen fertilizer, Animal science, chemistry, Nitrate, Composition (visual arts), Agronomy and Crop Science, Selenium
Abstract

The effects of selenium in rice grain composition depend on the soil nitrogen supply. Selenium and nitrogen have the potential to modify rice grain composition; however, it is unclear how the combined effect of Se and nitrogen affects the grain nutritional quality of rice. In our study, grain Se concentration was positively associated with the increased availability of nitrogen in soil. The accumulation of Se in grain of rice plants treated with Se combined with nitrogen was accompanied by an increase in expression of NRT1.1B, a rice nitrate transporter and sensor, in root. Moreover, Se potentiates the response of nitrogen supply in expression of sulfate transporter OsSULTR1.2, phosphate transporter OsPT2 and silicon transporter OsNIP2.1 in root, thereby increasing root Se uptake capacity. The combination of Se with high nitrogen increased the concentrations of protein, carbohydrates, Se, Mo and Mg, but decreased concentrations of Fe, Mn, Cu and Zn in grain. Overall, our results revealed that many of the effects of Se in rice grain composition are due to a shift in the nitrogen status of the plant.

Published
2021

45. Colecistopatias e o tratamento das suas complicações: uma revisão sistemática de literatura / Colecistopathies and the treatment of their complications: a systematic review of literature

Author

Andressa de Souza Abi-Rachid Moraes, Patrícia e Silva Dias, Yana de Medeiros Souza Lima, Bianca Barros Branco, M. Pimenta, Carlos Rafael Alves de Brito, Hamilton Cezar Rocha Garcia, Júlia Medeiros Santana, Pâmela Gabrielle Lima Barreiros, and Mateus de Souza Castro

Subjects
colangite, tratamento, complicação, colelitíase, diagnóstico, complicação, coledocolitíase, colangite, tratamento, General Medicine, colelitíase, coledocolitíase, diagnóstico
Abstract

Objetivo: Realizar uma revisão da literatura a fim de analisar as complicações mais frequentes da colelitíase, suas abordagens diagnósticas e terapêuticas. Método: Revisão sistemática e integrada de artigos originais e revisões que investigaram as complicações da colelitíase, abordando diagnóstico e tratamento. Foram incluídos artigos originais e revisões, publicados e indexados no MEDLINE, PubMed e Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde (BIREME). Discussão: O melhor exame para detectar a presença de cálculos na vesícula biliar é a ultrassonografia (USG) abdominal com uma acurácia de mais de 95%. As principais complicações são decorrentes da migração de um ou mais cálculos ou para o ducto cístico, ou para o colédoco. Um único cálculo que migrar pode causar uma complicação. Ao migrar e impactar no ducto cístico pode resultar em colecistite aguda; hidropsia de vesícula; síndrome de Mirizzi. Se ele conseguir atravessar o cístico e passar para o colédoco, pode obstruí-lo total ou parcialmente, provocando: coledocolitíase, colangite e pancreatite biliar. Cerca de 10-20% dos pacientes com colecistite aguda evoluem com graves complicações, que indicam cirurgia de urgência. Cerca de 10% dos pacientes com colelitíase apresentam cálculo no colédoco. A incidência aumenta nos idosos em 20-25%. Conclusão: Existem pontos convergentes quanto aos métodos diagnósticos da colelitíase e suas complicações como a coledocolitíase e a colangite bacteriana aguda. Independente do caso, sempre de ser feita a busca dos fatores clínicos, laboratoriais e de USG que sugiram a obstrução da via biliar comum.

Published
2021

46. Feasibility of using Clinical Practice Research Datalink data to identify patients with chronic obstructive pulmonary disease to enrol into real‐world trials

Author

Daniel Dedman, Rachael Williams, Jennifer K Quint, Jeanne M. Pimenta, Achim Wolf, Tarita Murray-Thomas, and Gema Requena

Subjects
Spirometry, Male, medicine.medical_specialty, Databases, Factual, Epidemiology, Pulmonary disease, 030226 pharmacology & pharmacy, 1117 Public Health and Health Services, chronic obstructive pulmonary disease, Cohort Studies, 03 medical and health sciences, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Disease severity, Internal medicine, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Pharmacology & Pharmacy, Asthma, Public, Environmental & Occupational Health, Aged, Data Management, Retrospective Studies, general practice, COPD, Science & Technology, medicine.diagnostic_test, business.industry, feasibility studies, real world clinical trials, Original Articles, electronic health record, medicine.disease, Comorbidity, United Kingdom, Clinical Practice, primary health care, Original Article, Female, 1115 Pharmacology and Pharmaceutical Sciences, business, Life Sciences & Biomedicine, Cohort study
Abstract

Purpose To assess the feasibility of using Clinical Practice Research Datalink (CPRD) data for identifying populations of patients with chronic obstructive pulmonary disease (COPD) eligible for a hypothetical pragmatic trial. Methods A retrospective multidatabase cohort study using CPRD primary care and linked secondary care data to describe the characteristics of populations of patients with COPD. Patients' demographic and lifestyle factors, comorbidity profile, spirometry measurements and treatment changes were evaluated, as was the distribution of follow‐up time and types of losses during follow‐up. Characteristics were evaluated using descriptive statistics. Results A total of 322 991 patients from 1148 primary care practices in the United Kingdom across two CPRD primary care databases, CPRD GOLD and CPRD Aurum, were potentially eligible to participate in a hypothetical trial using CPRD, starting on 31 December 2017. Patients with COPD in CPRD GOLD and CPRD Aurum were comparable in terms of age (median age 70 vs. 68 years), gender (50% vs. 52% male), disease severity (e.g., 25% vs. 24% Medical Research Council [MRC] dyspnoea score grades 3–5) and history of respiratory conditions (e.g., 43% vs. 38% asthma). High proportions of patients with COPD in CPRD GOLD and CPRD Aurum were available on 31 December 2012 for follow‐up at 1, 2, and 5 years (92%, 85% and 67%, respectively). Conclusions Patients and data from CPRD GOLD and CPRD Aurum were comparable across key aspects relevant to COPD trials. A pragmatic trial using CPRD to recruit patients with COPD is scientifically feasible.

Published
2021

47. EOSOLAR Project: Assessment of Wind Resources of a Coastal Equatorial Region of Brazil—Overview and Preliminary Results

Author

Arcilan T. Assireu, Felipe M. Pimenta, Ramon M. de Freitas, Osvaldo R. Saavedra, Francisco L. A. Neto, Audálio R. Torres Júnior, Clóvis B. M. Oliveira, Denivaldo C. P. Lopes, Shigeaki L. de Lima, Rafael B. S. Veras, Natália P. Saraiva, Luiz G. P. Marcondes, and Denisson Q. Oliveira

Subjects
Control and Optimization, Renewable Energy, Sustainability and the Environment, Energy Engineering and Power Technology, Electrical and Electronic Engineering, remote sensing, SODAR, LIDAR, micrometeorology tower, marine boundary layer, sea–land transition, wind speed profile, wind energy, solar energy, Engineering (miscellaneous), Energy (miscellaneous)
Abstract

The EOSOLAR project was designed to investigate the structure of the atmospheric boundary layer in an equatorial coastal zone, where the discontinuity of surface conditions induces non-stationarity gradients of wind speeds and the development of internal boundary layers. The proposed methodology considers several aspects of the sea–land transition meteorology that are essential for precisely estimating wind–solar energy potential and assessment of structural loads on wind turbines. Infrared (LIDAR) and acoustic (SODAR) ground-based remote sensing instruments and micrometeorological towers were installed in a near-shore equatorial area of northeast Brazil, in order to provide a comprehensive view of meteorological processes. This paper reports a description of the project study area, methodology, and instrumentation used. Details of instruments configurations, a validation of micrometeorology towers, and a comparison between the LIDAR and SODAR are presented. Results of the first field campaign measuring the coastal flow, integrating the micrometeorological tower and LIDAR observations are described.

Published
2022
Full Text
View/download PDF

48. Belimumab use during pregnancy: a summary of birth defects and pregnancy loss from belimumab clinical trials, a pregnancy registry and postmarketing reports

Author

Michelle Petri, Helain Landy, Megan E B Clowse, Kim Gemzoe, Munther Khamashta, Milena Kurtinecz, Roger A Levy, Andrew Liu, Rebecca Marino, Paige Meizlik, Jeanne M Pimenta, Kelsey Sumner, Hugh Tilson, Mary Beth Connolly, Keele Wurst, Julia Harris, Holly Quasny, Patricia Juliao, and David A Roth

Subjects
Rheumatology, Immunology, Immunology and Allergy, General Biochemistry, Genetics and Molecular Biology
Abstract

ObjectiveDescribe available data on birth defects and pregnancy loss in women with systemic lupus erythematosus (SLE) exposed to belimumab.MethodsData collected from belimumab clinical trials, the Belimumab Pregnancy Registry (BPR), and postmarketing/spontaneous reports up to 8 March 2020 were described. Belimumab exposure timing, concomitant medications and potential confounding factors were summarised descriptively.ResultsAmong 319 pregnancies with known outcomes (excluding elective terminations), 223 ended in live births from which birth defects were identified in 4/72 (5.6%) in belimumab-exposed pregnancies and 0/9 placebo-exposed pregnancies across 18 clinical trials, 10/46 (21.7%) belimumab-exposed pregnancies in the BPR prospective cohort (enrolled prior to pregnancy outcome) and 0/4 belimumab-exposed pregnancies in the BPR retrospective cohort (enrolled after pregnancy outcome), and 1/92 (1.1%) in belimumab-exposed pregnancies from postmarketing/spontaneous reports. There was no consistent pattern of birth defects across datasets. Out of pregnancies with known outcomes (excluding elective terminations), pregnancy loss occurred in 31.8% (35/110) of belimumab-exposed women and 43.8% (7/16) of placebo-exposed women in clinical trials; 4.2% (2/48) of women in the BPR prospective cohort and 50% (4/8) in the BPR retrospective cohort; and 31.4% (43/137) of belimumab-exposed women from postmarketing/spontaneous reports. All belimumab-exposed women in clinical trials and the BPR received concomitant medications and had confounding factors and/or missing data.ConclusionsObservations reported here add to limited data published on pregnancy outcomes following belimumab exposure. Low numbers of exposed pregnancies, presence of confounding factors/other biases, and incomplete information preclude informed recommendations regarding risk of birth defects and pregnancy loss with belimumab use.

Published
2022

50. Characteristics Associated with Accelerated Lung Function Decline in a Primary Care Population with Chronic Obstructive Pulmonary Disease

Author

Hannah R Whittaker, Steven J. Kiddle, Deborah Jarvis, Jennifer K Quint, and Jeanne M. Pimenta

Subjects
Spirometry, medicine.medical_specialty, Population, Logistic regression, 03 medical and health sciences, FEV1/FVC ratio, 0302 clinical medicine, Internal medicine, medicine, 030212 general & internal medicine, education, Lung function, COPD, education.field_of_study, medicine.diagnostic_test, business.industry, General Medicine, respiratory system, medicine.disease, respiratory tract diseases, 030228 respiratory system, Quartile, Underweight, medicine.symptom, business, circulatory and respiratory physiology
Abstract

Background Estimates for lung function decline in chronic obstructive pulmonary disease (COPD) have differed by study setting and have not been described in a UK primary care population. Purpose To describe rates of FEV1 and FVC decline in COPD and investigate characteristics associated with accelerated decline. Patients and Methods Current/ex-smoking COPD patients (35 years+) who had at least 2 FEV1 or FVC measurements ≥6 months apart were included using Clinical Practice Research Datalink. Patients were followed up for a maximum of 13 years. Accelerated rate of lung function decline was defined as the fastest quartile of decline using mixed linear regression, and association with baseline characteristics was investigated using logistic regression. Results A total of 72,683 and 50,649 COPD patients had at least 2 FEV1 or FVC measurements, respectively. Median rates of FEV1 and FVC changes or decline were −18.1mL/year (IQR: −31.6 to −6.0) and −22.7mL/year (IQR: −39.9 to −6.7), respectively. Older age, high socioeconomic status, being underweight, high mMRC dyspnoea and frequent AECOPD or severe AECOPD were associated with an accelerated rate of FEV1 and FVC decline. Current smoking, mild airflow obstruction and inhaled corticosteroid treatment were additionally associated with accelerated FEV1 decline whilst women, sputum production and severe airflow obstruction were associated with accelerated FVC decline. Conclusion Rate of FEV1 and FVC decline was similar and showed similar heterogeneity. Whilst FEV1 and FVC shared associations with baseline characteristics, a few differences highlighted the importance of both lung function measures in COPD progression. We identified important characteristics that should be monitored for disease progression.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results