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This study aimed to consider the effect of differing transcranial direct current stimulation (tDCS) parameters on eating-related measures and how issues with experimental design (e.g., inadequate blinding) or parameters variation may drive equivocal effects.Literature searches were conducted across MEDLINE, PsycINFO, Scopus, and Science Direct. Studies using conventional sham-controlled tDCS to modify eating-related measures in adult human participants were included. A total of 1135 articles were identified and screened by two independent authors. Study quality was assessed using the Risk of Bias tool. Random-effects meta-analyses were performed, with subgroup analyses to determine differences between parameter sets.We identified 28 eligible studies; 7 showed low risk of bias, with the remaining studies showing bias arising from issues implementing or reporting blinding protocols. Large variation in applied parameters was found, including montage, current intensity and density, participant and researcher blinding, and the use of online or offline tasks. The application of differing parameters seemed to alter the effects of tDCS on eating-related measures, particularly for current density ( g = -0.25 to 0.31), and when comparing single-session ( g = -0.08 to 0.01) versus multisession protocols ( g = -0.34 to -0.29). Some parameters result in null effects.The absence of tDCS-mediated change in eating-related measures may be driven by variation in applied parameters. Consistent application of parameters that seem to be effective for modulating eating behavior is important for identifying the potential impact of tDCS. Using the findings of this review, we propose a series of parameters that researchers should apply in their work.

This large, international dataset contains survey responses from N = 12,570 students from 100 universities in 35 countries, collected in 21 languages. We measured anxieties (statistics, mathematics, test, trait, social interaction, performance, creativity, intolerance of uncertainty, and fear of negative evaluation), self-efficacy, persistence, and the cognitive reflection test, and collected demographics, previous mathematics grades, self-reported and official statistics grades, and statistics module details. Data reuse potential is broad, including testing links between anxieties and statistics/mathematics education factors, and examining instruments’ psychometric properties across different languages and contexts. Data and metadata are stored on the Open Science Framework website [https://osf.io/mhg94/].

Vasoactive ingredients in beetroot (BR) such as nitrate are known to induce vasodilation in temperate conditions. This study investigated the effect of BR ingestion on cold induced vasodilation (CIVD) and rewarming of finger skin temperature (TTwenty healthy males (mean ± SD; age 22.2 ± 0.7 years, height 172.6 ± 6.0 cm, body mass 61.3 ± 11.7 kg) repeated a hand cold water immersion test twice with prior BR or water beverage ingestion (randomised order). They rested for 2 h in thermoneutral conditions (27 °C, 40% relative humidity) after consuming the beverage, then immersed their non-dominant hand in 8 °C water for 30 min. They then rewarmed their hand in the ambient air for 20 min. Skin temperature at seven body sites, TDuring hand immersion parameters of CIVD (TBR accelerated rewarming in T

Introduction Many young adults demonstrate insufficient rates of physical activity (PA) to yield health benefits. The study tested the effectiveness of a text messaging intervention targeting key psychological determinants and PA. Methods Participants received either attitude messages, goal priority messages, a combination of these, or generic PA information (control). After confirming that groups were matched at baseline, a 2 (attitude: yes vs. no) by 2 (goal priority: yes vs. no) by 2 (time: immediately post-intervention, four weeks post-intervention) randomized control trial tested main and interactive effects. Results Results showed participants that received attitude messages had significantly more positive attitudes, intentions and rates of PA. Mediational analyses showed the influence of attitude messages on PA to be fully mediated through the serial path via attitude and intention. There were no other main or interactive effects. Conclusion The study provides support for using attitudinal messages delivered via text messaging to influence key psychological determinants and PA.

Purpose: Rowers can be in marshaling areas for up to 20 to 25 min before the start of a race, which likely negates any benefits of an active warm-up, especially in cold environments. It is unknown if using a heated jacket following a standardized rowing warm-up can improve 2000-m rowing performance. Methods: On 2 separate occasions, 10 trained male rowers completed a standardized rowing warm-up, followed by 25 min of passive rest before a 2000-m rowing time trial on a rowing ergometer. Throughout the passive rest, the participants wore either a standardized tracksuit top (CON) or an externally heated jacket (HEAT). The trials, presented in a randomized crossover fashion, were performed in a controlled environment (temperature 8°C, humidity 50%). Rowing time-trial performance, core body temperature, and mean skin temperature, along with perceptual variables, were measured. Results: During the 25-min period, core body temperature increased in HEAT and decreased in CON (Δ0.54°C [0.74°C] vs −0.93°C [1.14°C]; P = .02). Additionally, mean skin temperature (30.22°C [1.03°C] vs 28.86°C [1.07°C]) was higher in HEAT versus CON (P P Conclusion: The data demonstrate that an upper-body external heating garment worn following a warm-up can improve rowing performance in a cool environment.

Purpose: The Doha 2019 women’s World Championship marathon took place in extreme hot (32 °C), humid conditions (74% relative humidity) culminating in unprecedented (41%) failure rates. We explored whether extreme heat or suboptimal pacing was responsible for diminished performance against a temperate “control” (London 2017: 19 °C, 59% relative humidity) and whether physical characteristics (eg, body surface area, estimated maximal oxygen uptake, habitual heat exposure) explained performance. Method: Five-kilometer-pace (km·h−1) data underwent repeated-measures analyses of hot (Doha, n = 40) versus temperate pacing and performance (London, n = 78) within and between marathon pacing (finisher quartiles normalized against personal best; n = 10 per group) and within hot marathon finishers versus nonfinishers (up to 10 km; normalized data). Possible predictors (multiple regression) of hot marathon pacing were explored. Tests to .05 alpha level, partial eta squared () indicates effect size. Results: Mean (SD) of Doha (14.82 [0.96] km·h−1) pace was slower (London: 15.74 [0.96] km·h−1; P = .00; ). In hot conditions, athletes finishing in positions 1 to 10 (group 1) started more conservatively (93.7% [2.1%] of personal best) than slower runners (groups 3 and 4; 96.6% [2.8%] of personal best; P ). Groups were not different at 15 km and then slowed immediately (groups 3 and 4) or after 20 km (group 2). Finishers and nonfinishers adopted similar pace up to 10 km (P > .05, ). World ranking predicted (P = .00; r2 = .248) average pace in Doha. Conclusion: Extreme hot conditions reduced performance. Top 10 athletes adopted a conservative initial pace, whereas lower-placing athletes adopted a faster, aggressive start. Pacing alone does not explain high failure rates in nonfinishers. Athletes competing in the heat should initially pace conservatively to optimize performance.

Purpose: Exercise performance is impaired in the heat, and a contributing factor to this decrement is thermal discomfort. Menthol spraying of skin is one means of alleviating thermal discomfort but has yet to be shown to be ergogenic using single-spray applications. The authors examined whether repeated menthol spraying could relieve thermal discomfort, reduce perception of exertion, and improve exercise performance in hot (35°C), dry (22% relative humidity) conditions, hypothesizing that it would. Methods: A total of 8 trained cyclists completed 2 separate conditions of fixed-intensity cycling (50% maximal power output) for 45 min before a test to exhaustion (TTE; 70% maximal power output) with 100 mL of menthol spray (0.20% menthol) or control spray applied to the torso after 20 and 40 min. Perceptual (thermal sensation, thermal comfort, and rating of perceived exertion) performance (TTE duration), thermal variables (skin temperature, rectal temperature, and cardiac frequency), and sweating were measured. Data were compared using analysis of variance to .05 alpha level. Results: Menthol spray improved thermal sensation (cold sensation cf warm/hot after first spraying; P = .008) but only descriptively altered thermal comfort (comfortable cf uncomfortable; P = .173). Sweat production (994 [380] mL cf 1180 [380] mL; P = .020) and sweat rate (827 [327] mL·h−1 cf 941 [319] mL·h−1; P = .048) lowered. TTE performance improved (4.6 [1.74] cf 2.4 [1.55] min; P = .004). Menthol-spray effects diminished despite repeated applications, indicating increased contribution of visceral thermoreceptors to thermal perception. Conclusion: Repeated menthol spraying improves exercise capacity but alters thermoregulation, potentially conflicting behavioral and thermoregulatory drivers; care should be taken with its use. Carrying and deploying menthol spray would impose a logistical burden that needs consideration against performance benefit.

Transcranial direct current stimulation (tDCS) is becoming an increasingly popular technique for altering eating behaviors. Recent research suggests a possible eating behavior trait-dependent effect of tDCS. However, studies recruit participant populations with heterogeneous trait characteristics, including "healthy" individuals who do not present with eating behavior traits suggesting susceptibility to overconsumption. The present review considers the effects of tDCS across eating-related measures and explores whether a trait-dependent effect is evident across the literature. A literature search identified 28 articles using sham-controlled tDCS to modify eating-related measures. Random effects meta-analyses were performed, with subgroup analyses to identify differences between "healthy" and trait groups. Trivial overall effects (g = -0.12 to 0.09) of active versus sham tDCS were found. Subgroup analyses showed a more consistent effect for trait groups, with small and moderate effect size (g = -1.03 to 0.60), suggesting tDCS is dependent on participants' eating behavior traits. Larger effect sizes were found for those displaying traits associated with study outcomes (e.g., heightened food cravings). "Healthy" individuals appear to be unresponsive to stimulation. Based on this meta data, future work should recruit those with eating behavior trait susceptibilities to overconsumption, focusing on those who present with traits associated with the outcome of interest.

The determinants of energy saving phenomena reported for load carried on the head, back and in a doublepack remain unclear. This study compared the energetic, kinematic and kinetic responses to head (H), back (B) and doublepack (DP) loading. Fifteen volunteers walked on an instrumented treadmill at 3 km.h-1 with 0, 3, 12 and 20 kg in each loading method. Whole body motion, ground reaction forces (GRF) and metabolic cost were measured. H was less economical than B (p = 0.014) and DP (p = 0.010). H was also associated with increased step length (p = 0.045), decreased cadence (p = 0.001), greater trunk (p

Purpose: To quantify the peak post-pitch-entry physical responses of soccer substitutes while assessing contextual influences. Peak responses may be important performance indicators for substitutes introduced to provide a physical impact. Method: Thirty-three professional substitutes wore Microelectromechanical Systems during 44 matches (4 ± 3 observations·player-1). Post-pitch-entry relative peak values for total and high-speed (> 5.5 m·s-1) distances, average acceleration, and PlayerLoad™ were calculated using rolling averages over 60-s to 600-s. Linear mixed models assessed contextual influences (position, substitution timing, scoreline, and location). Results: Substitutes introduced during the final ~15 min of match-play covered less high-speed distance than first-half substitutes (~2.8-3.1 m·min-1) over 480-s to 600-s epochs, and less than 60:00-74:59 min substitutes (~1.7-1.8 m·min-1) during 540-s and 600-s epochs. Average acceleration during all except 180-s epochs was lower for 75:00+ min substitutes compared with first-half replacements (~0.27-0.43 m·s-2), and lower than 60:00-74:59 min substitutes during 60-s (~0.13 m·s-2). Substitutes introduced when their team was winning recorded greater distances over 120-s to 600-s (~6.2-7.7 m·min-1), and higher PlayerLoad™ values during 120-s, 180-s, 300-s, and 480-s epochs (~2.7-3.6 arbitrary units·min-1), compared with when scores were level at pitch-entry. Irrespective of substitution timing, substitute midfielders exceeded the total distance of substitute attackers (~5.9-16.2 m·min-1) for all except 360-s and 600-s epochs, and defenders (~13.3-26.7 m·min-1) during epochs < 300-s. Conclusions: This study provides benchmark data for practitioners tailoring training and recovery protocols, particularly "top-up" conditioning, to the competitive demands of soccer substitutes. Knowing how contextual factors influence substitutes' peak match-play responses may help managers/coaches assess the efficacy of substitution strategies.

Hills, SP, Barrett, S, Busby, M, Kilduff, LP, Barwood, MJ, Radcliffe, JN, Cooke, CB, and Russell, M. Profiling the post-match top-up conditioning practices of professional soccer substitutes: An analysis of contextual influences. J Strength Cond Res 34(10): 2805-2814, 2020-Soccer practitioners implement "top-up" conditioning sessions to compensate for substitutes' limited match-play exposure. Although perceived to be valuable for reducing injury risk and augmenting positive physical adaptations, little research has considered the demands of post-match top-up training. To quantify post-match top-up responses, 31 professional soccer players wore 10 Hz microelectromechanical systems after 37 matches whereby they were selected in the match-day squad as substitutes (184 observations; 6 ± 5 observations·player). Linear mixed models and effect sizes (ES) assessed the influence of contextual factors on 23 physical performance variables. Top-ups lasted 17.13 ± 7.44 minutes, eliciting total and high-speed distances of 1.7 ± 6.2 km and 0.4 ± 1.7 km, respectively. Each contextual factor (i.e., position, substitution timing, match location, result, time of day, stage of the season, and fixture density) influenced at least 4 of the dependent variables profiled (p ≤ 0.05). Top-up duration; total, moderate-speed, and low-speed distance; and the number of repeated high-intensity efforts were greater for unused vs. used substitutes (ES: 0.38-0.73, small to moderate). Relative to away matches, home top-ups elicited heightened total, low-speed, and high-speed distances, alongside more moderate-speed accelerations and decelerations, and repeated high-intensity efforts (ES: 0.25-0.89, small to moderate). Although absolute and relative running distances were generally the highest when the fixture density was low, the greatest acceleration and deceleration demands were observed during the most congested fixture periods. Late-season top-ups typically elicited lower absolute physical responses than early and mid-season sessions. These data provide important information for practitioners when considering the aims and design of substitute top-up conditioning sessions, particularly with reference to contextual influences.

BACKGROUND: \ud Cycling downhill accelerates heat loss and requires lower work rates leading to cold discomfort. Historically, cyclists have behaviorally thermoregulated prior to cycling downhill by inserting newspapers into their jerseys. Yet, there is no experimental data to support such a method showing improvements in thermal perception and profile; we hypothesized it would. \ud METHODS: \ud Two cohorts (n=8 each) of male participants completed two main trials each involving 30-minutes simulated uphill cycling (65% VO2peak 188 (41)W; no fan) followed by 15-minutes downhill cycling (35% VO2peak 41 (12)W) in front of an industrial fan (wind speed: 4.6 (0.1)m·s-1). In one trial participants inserted one (study 1) or two (study 2) tabloid newspapers into their jerseys (PAPER) prior to downhill cycling; the other was a control (NOPAPER). Whole body and torso thermal sensation (TS) and comfort (TC), aural temperature (Tau), skin temperature (Tskin), and newspaper mass change (Δ) were measured. Data were compared using ANOVA and t-test to 0.05 alpha level. RESULTS: \ud After uphill cycling thermal and perceptual profiles were similar. In study 1, only TC was transiently improved 1-minute after newspaper insertion. In study 2, Tskin rate of decline was lower in the PAPER condition (−0.11 (0.12)ºC.min-1 cf −0.53 (0.16)ºC.min-1; p = .001) and Tchest remained higher (28.83 (3.17)ºC cf 24.39 (3.22)ºC). This improved TS but not TC. Newspaper mass increased indicating impaired sweat evaporation (Δmass: 5.7 (4.9)g; p=0.01). \ud CONCLUSIONS: \ud Thermal perception and profile during downhill cycling was improved by inserting two newspapers but not one newspaper into the jersey, supporting our hypothesis.

Data Availability: The dataset generated during and analysed during the current study are available in the Leeds Trinity University, PURE Institutional repository, https://research.leedstrinity.ac.uk/en/publicatio ns/menthol-as-an-ergogenic-aid-for-the-tokyo-2021-olympic-games -an-expert-led-consensus-statement-using-the-modified-delphi-metho d(7a4e8d11-b997-4cc6-b2ef-b6e6927997b8).html. © The Author(s) 2020. Introduction Menthol topical application and mouth rinsing are ergogenic in hot environments, improving performance and perception, with differing effects on body temperature regulation. Consequently, athletes and federations are beginning to explore the possible benefits to elite sport performance for the Tokyo 2021 Olympics, which will take place in hot (~ 31 °C), humid (70% RH) conditions. There is no clear consensus on safe and effective menthol use for athletes, practitioners, or researchers. The present study addressed this shortfall by producing expert-led consensus recommendations. Method Fourteen contributors were recruited following ethical approval. A three-step modified Delphi method was used for voting on 96 statements generated following literature consultation; 192 statements total (96/96 topical application/mouth rinsing). Round 1 contributors voted to “agree” or “disagree” with statements; 80% agreement was required to accept state- ments. In round 2, contributors voted to “support” or “change” their round 1 unaccepted statements, with knowledge of the extant voting from round 1. Round 3 contributors met to discuss voting against key remaining statements. Results Forty-seven statements reached consensus in round 1 (30/17 topical application/rinsing); 14 proved redundant. Six statements reached consensus in round 2 (2/4 topical application/rinsing); 116 statements proved redundant. Nine further statements were agreed in round 3 (6/3 topical application/rinsing) with caveats. Discussion Consensus was reached on 62 statements in total (38/24 topical application/rinsing), enabling the development of guidance on safe menthol administration, with a view to enhancing performance and perception in the heat without impairing body temperature regulation.

Modifying a soccer substitute’s pre-pitch-entry activities may represent an opportunity to maximise physical performance and minimise injury-risk following match-introduction. Using a professional team that has previously participated in substitute profiling research, this follow-up case study investigated the effects of a modified match-day protocol that included substitutes; 1) performing a new pre-match warm-up alongside members of the starting team (as opposed to a separate substitute-only warm-up), 2) participating in a staff-led half-time rewarm-up (as opposed to player-led half-time activities), and 3) receiving ongoing education focusing on the efficacy of (re)warm-up activities. English Championship substitutes (n = 15) were monitored using Micro-electromechanical Systems during 13 matches incorporating the modified practices (35 observations). On an individual player basis, data were organised into bouts of warm-up activity (pre-pitch-entry) and five min epochs of match-play (post-pitch-entry). Linear mixed modelling assessed the influence of ‘bout’ and ‘epoch’, position, and scoreline. Substitutes performed 3±1 rewarm-up bouts∙player-1∙match-1 between kick-off and pitch-entry, which were shorter (-17.2 to -27.1 min) and elicited less distance (-696 to -1257 m) than the pre-match warm-up (p≤0.001). Compared with previous data, heightened absolute movement responses were observed during the pre-match and staff-led half-time (re)warm-ups, alongside greater relative distances covered during player-led activities performed between kick-off and pitch-entry. Whilst less distance (-10%) was covered during the second versus first five min period following match-introduction, values remained higher than previously reported. Between pitch-entry and the end of the match, the scoreline improved and worsened following 26% and 11% of substitutions, respectively; a favourable record compared with existing observations. Acknowledging the likely contribution from external factors, this case study reports heightened movement profiles and improved match scorelines when pre-pitch-entry practices were modified. Practitioners should note the potential influence of match-day activities on the physical responses of soccer substitutes and, if deemed necessary, consider adapting their pre-pitch-entry routines accordingly.

OBJECTIVES: To profile performance and physiological responses to typical patterns of match-day activity for second-half soccer substitutes. DESIGN: Descriptive. METHODS: Following a warm-up, 13 male team sports players underwent ∼85min of rest, punctuated with five min rewarm-ups at ∼25, ∼50, and ∼70min, before ∼30min of simulated soccer match-play. Countermovement jump performance (jump height, peak power output), alongside 15m sprints, were assessed post-warm-up, and pre- and post-simulated match-play. Core temperature, heart rate, ratings of perceived exertion, and blood glucose and lactate concentrations were measured throughout. RESULTS: Warm-up-induced core temperature elevations (∼2.3%, +0.85°C; p

Depending upon competition regulations, the laws of soccer allow between three and an unlimited number of substitutions that can be made on either a permanent or rolling basis. Substitutes are typically introduced to minimise/offset the effects of fatigue, alter tactics, replace players deemed as underperforming or injured, and/or give playing time to youth players or to squad members returning from injury. While the match-day practices of substitutes include participation in the pre-match warm-up, and sporadic periods of rewarm-up activity, it is currently unclear as to whether these pre-entry preparations facilitate optimal match performance thereafter. Acknowledging the contextual factors that possibly influence substitutes' performance, this review summarises the presently available literature on soccer substitutes, and makes recommendations for future research. Literature searching and screening yielded 13 studies, which have typically focused on characterising: (1) the patterns, including timing, of substitutes' introduction; (2) indices of match-performance; and (3) the emotional experiences of soccer substitutes. The majority of substitutions occur after the first-half has ended (i.e. at half-time or during the second-half), with introduced players exceeding the second-half physical performances of those who started the match. Observations of progressive improvements in running performance as playing time increases, and findings that substitutes mostly experience negative emotions, highlight the potential inadequacies of pre-match preparations, and present future research opportunities. Additional work is therefore needed to confirm these findings and to determine the efficacy of current preparation strategies, thereby providing opportunities to assess then address substitutes' pre-pitch entry preparations, on-field performance and emotional responses.

Background - It has been suggested that pacing is a thermoregulatory behaviour. We investigated the effect of competition on pacing, performance, and thermophysiological strain during exercise in the heat and the psychological factors mediating competition effects. Method - Eighteen males (VO2max=3.69(0.44) L·min-1) undertook a preliminary 20 km cool (WBGT=12°C) cycling time-trial (TT) and three experimental 20 km trials (balanced order): i) cool TT (CoolSolo); ii) hot (WBGT=26°C) TT (HotSolo); iii) hot head-to-head competition (HotH2H). During TTs an avatar of the participant’s performance was visible. During HotH2H participants believed they were competing against another participant, but the competitor’s avatar replicated their own preliminary (cool) TT. Results - TTs (min:sec) slowed with increased ambient temperature (CoolSolo=35:31(2:11) vs. HotSolo=36:10(2:26), P=0.011). This effect was negated by competition; performances were not different between HotH2H (35:17(1:52) and CoolSolo (P=0.160) and were quicker in HotH2H vs. HotSolo (P=0.001). End-exercise rectal temperature, mean body temperature and physiological strain index were (Pr=0.608, P=0.010) and participants’ propensity for deliberate risk-taking (B=0.12, PB=-9.40, P=0.010). Conclusion - Competition changes the relationship between perceived and actual thermophysiological state, altering behavioral thermoregulation and increasing thermophysiological strain; this could increase heat-illness risk. Psychophysiological and psychological measures may identify susceptible individuals.

Background - Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulatory technique and has previously been shown to enhance submaximal exercise by reducing rating of perceived exertion (RPE). The present study examined the effects of tDCS on high-intensity self-paced exercise in temperate conditions and fixed followed by maximal exercise in the heat; it was hypothesised that performance and RPE would be altered.Methods - Two separate studies were undertaken in which exercise was preceded by 20-minutes of sham tDCS (SHAM), or anodal tDCS (TDCS). In study 1, six males completed a 20-km cycling time trial, on two occasions. Power output (PO), RPE, O2 pulse, and heart rate (HR) were measured throughout. In study 2, eight males completed fixed intensity cycling exercise at 55% of a pre-determined maximal power output (PMax) for 25-minutes before undertaking a time to exhaustion test (TTE; 75% PMax) in hot conditions (33 °C), on two occasions. Test duration, heart rate, thermal and perceptual responses were measured. Study specific and combined statistical analyses were undertaken and effect sizes established.Results - In study 1, mean PO was not improved with the tDCS (197 ± 20 W) compared to SHAM (197 ± 12 W) and there were no differences in pacing profile HR, O2 pulse or RPE (p > .05). In study 2, TTE duration (SHAM 314 ± 334 s cf 237 ± 362 s tDCS), thermal, heart rate and perceptual responses were unchanged by tDCS compared to SHAM (p > .05). When combined, performance in the SHAM trial tended to better than the tDCS.Conclusion - tDCS did not influence cycling performance (study 1) exercise tolerance (study 2) or perception (studies 1 and 2). tDCS does not appear to facilitate high intensity exercise performance or exercise performance in the heat.

Whilst the movement demands of players completing a whole soccer match have been well-documented, comparable information relating to substitutes is sparse. Therefore, this study profiled the match-day physical activities performed by soccer substitutes, focusing separately on the pre and post pitch-entry periods. Seventeen English Championship soccer players were monitored using 10 Hz Micromechanical Electrical Systems (MEMS) devices during 13 matches in which they participated as substitutes (35 observations). Twenty physical variables were examined and data were organised by bouts of warm-up activity (pre pitch-entry), and five min epochs of match-play (post pitch-entry). Linear mixed modelling assessed the influence of time (i.e., ‘bout’ and ‘epoch’), playing position, and match scoreline. Substitutes performed 3±1 rewarm-up bouts∙player−¹∙match−¹. Compared to the initial warm-up, each rewarm-up was shorter (-19.7 to -22.9 min) and elicited less distance (-606 to -741 m), whilst relative total distances were higher (+26 to +69 m∙min−¹). Relative total (+13.4 m∙min−¹) and high-speed (+0.4 m∙min−¹) distances covered during rewarm-ups increased (p

Introduction: Drowning is a leading cause of accidental death. In cold-water, sudden skin cooling triggers the life-threatening cold shock response (CSR). The CSR comprises tachycardia, peripheral vasoconstriction, hypertension, inspiratory gasp, and hyperventilation with the hyperventilatory component inducing hypocapnia and increasing risk of aspirating water to the lungs. Some CSR components can be reduced by habituation (i.e., reduced response to stimulus of same magnitude) induced by 3–5 short cold-water immersions (CWI). However, high levels of acute anxiety, a plausible emotion on CWI: magnifies the CSR in unhabituated participants, reverses habituated components of the CSR and prevents/delays habituation when high levels of anxiety are experienced concurrent to immersions suggesting anxiety is integral to the CSR.Purpose: To examine the predictive relationship that prior ratings of acute anxiety have with the CSR. Secondly, to examine whether anxiety ratings correlated with components of the CSR during immersion before and after induction of habituation.Methods: Forty-eight unhabituated participants completed one (CON1) 7-min immersion in to cold water (15°C). Of that cohort, twenty-five completed four further CWIs that would ordinarily induce CSR habituation. They then completed two counter-balanced immersions where anxiety levels were increased (CWI-ANX) or were not manipulated (CON2). Acute anxiety and the cardiorespiratory responses (cardiac frequency [fc], respiratory frequency [fR], tidal volume [VT], minute ventilation [E]) were measured. Multiple regression was used to identify components of the CSR from the most life-threatening period of immersion (1st minute) predicted by the anxiety rating prior to immersion. Relationships between anxiety rating and CSR components during immersion were assessed by correlation.Results: Anxiety rating predicted the fc component of the CSR in unhabituated participants (CON1; p < 0.05, r = 0.536, r2 = 0.190). After habituation immersions (i.e., cohort 2), anxiety rating predicted the fR component of the CSR when anxiety levels were lowered (CON2; p < 0.05, r = 0.566, r2 = 0.320) but predicted the fc component of the CSR (p < 0.05, r = 0.518, r2 = 0.197) when anxiety was increased suggesting different drivers of the CSR when anxiety levels were manipulated; correlation data supported these relationships.Discussion: Acute anxiety is integral to the CSR before and after habituation. We offer a new integrated model including neuroanatomical, perceptual and attentional components of the CSR to explain these data.

INTRODUCTION\ud \ud Accidental cold-water immersion (CWI) evokes the life threatening cold shock response (CSR) which increases the risk of drowning. Consequently, the safety behaviour selected is critical in determining survival; the present advice is to 'float first' and remain stationary (i.e. rest). We examined whether leg only exercise (i.e., treading water; 'CWI-Kick') immediately on CWI could reduce the symptoms of the CSR, offset the reduction in cerebral blood flow that is known to occur and reduce the CSR's symptoms of breathlessness. We also examined whether perceptual responses instinctive to accidental CWI were exacerbated by this alternative behaviour. We contrasted CWI-Kick to a 'CWI-Rest' condition and a thermoneutral control (35°C); 'TN-Rest'.\ud \ud METHOD\ud \ud Seventeen participants were tested (9 males, 8 females). All immersions were standardised; water temperature in cold conditions (i.e., 12°C) was matched ±/0.5°C within participant. Middle cerebral artery blood flow velocity (MCAv) and cardiorespiratory responses were measured along with thermal perception (sensation and comfort) and dyspnoea. Data were analysed using repeated measures ANOVA (alpha level of 0.05).\ud \ud RESULTS\ud \ud MCAv was significantly reduced in CWI-Rest (-6 (9)%; 1st minute of immersion) but was offset by leg only exercise immediately on cold water entry; CWI-Kick MCAv was never different to TN-Rest (-3 (16)% cf. 5 (4)%). All CWI cardiorespiratory and perceptual responses were different to TN-Rest but were not exacerbated by leg only exercise.\ud \ud DISCUSSION\ud \ud Treading water may aid survival by offsetting the reduction in brain blood flow velocity without changing the instinctive behavioural response (i.e. perceptions). "Float first - and kick for your life" would be a suitable amendment to the water safety advice.

Purpose - Accidental cold-water immersion (CWI) impairs swim performance, increases drowning risk and often occurs whilst clothed. The impact of clothing on thermoregulation and swim performance during CWI was explored with the view of making recommendations on whether swimming is viable for self-rescue; contrary to the traditional recommendations.Method - Ten unhabituated males (age 24 (4) years; height 1.80 (0.08) m; mass 78.50 (10.93) kg; body composition 14.8 (3.4) fat %) completed four separate CWIs in 12 °C water. They either rested clothed or naked (i.e. wearing a bathing costume) or swum self-paced clothed or naked for up to 1 h. Swim speed, distance covered, oxygen consumption and thermal responses (rectal temperature (T re), mean skin temperature (T msk) and mean body temperature T b) were measured.Results - When clothed, participants swum at a slower pace and for a significantly shorter distance (815 (482) m, 39 (19) min) compared to when naked (1264 (564) m, 52 (18) min), but had a similar oxygen consumption indicating clothing made them less efficient. Swimming accelerated the rate of T msk and T b cooling and wearing clothing partially attenuated this drop. The impairment to swimming performance caused by clothing was greater than the thermal benefit it provided; participants withdrew due to exhaustion before hypothermia developed.Conclusion - Swimming is a viable self-rescue method in 12 °C water, however, clothing impairs swimming capability. Self-rescue swimming could be considered before clinical hypothermia sets in for the majority of individuals. These suggestions must be tested for the wider population.

Recent marine accidents have called into question the level of protection provided by immersion suits in real (harsh) life situations. Two immersion suit studies, one dry and the other with 500 mL of water underneath the suit, were conducted in cold water with 10–12 males in each to test body heat loss under three environmental conditions: calm, as mandated for immersion suit certification, and two combinations of wind plus waves to simulate conditions typically found offshore. In both studies mean skin heat loss was higher in wind and waves vs. calm; deep body temperature and oxygen consumption were not different. Mean survival time predictions exceeded 36 h for all conditions in the first study but were markedly less in the second in both calm and wind and waves. Immersion suit protection and consequential predicted survival times under realistic environmental conditions and with leakage are reduced relative to calm conditions.

L-menthol stimulates cutaneous thermoreceptors and induces cool sensations improving thermal comfort, but has been linked to heat storage responses; this could increase risk of heat illness during self-paced exercise in the heat. Therefore, L-menthol application could lead to a discrepancy between behavioral and autonomic thermoregulatory drivers. Eight male participants volunteered. They were familiarized and then completed two trials in hot conditions (33.5 °C, 33% relative humidity) where their t-shirt was sprayed with CONTROL-SPRAY or MENTHOL-SPRAY after 10 km (i.e., when they were hot and uncomfortable) of a 16.1-km cycling time trial (TT). Thermal perception [thermal sensation (TS) and comfort (TC)], thermal responses [rectal temperature (Trec), skin temperature (Tskin)], perceived exertion (RPE), heart rate, pacing (power output), and TT completion time were measured. MENTHOL-SPRAY made participants feel cooler and more comfortable and resulted in lower RPE (i.e., less exertion) yet performance was unchanged [TT completion: CONTROL-SPRAY 32.4 (2.9) and MENTHOL-SPRAY 32.7 (3.0) min]. Trec rate of increase was 1.40 (0.60) and 1.45 (0.40) °C/h after CONTROL-SPRAY and MENTHOL-SPRAY application, which were not different. Spraying L-menthol toward the end of self-paced exercise in the heat improved perception, but did not alter performance and did not increase heat illness risk.

The development of central fatigue is prominent following exercise-induced hyperthermia, but the contribution of supraspinal fatigue is not well understood. Seven endurance-trained cyclists (mean ± SD peak O2 uptake, 62.0 ± 5.6 mL/kg/min) completed two high-intensity constant-load cycling trials (296 ± 34 W) to the limit of tolerance in a hot (34 °C, 20% relative humidity) and, on a separate occasion, for the same duration, a control condition (18 °C, 20% relative humidity). Core body temperature (Tc) was measured throughout. Before and immediately after each trial, twitch responses to supramaximal femoral nerve and transcranial magnetic stimulation were obtained from the knee extensors to assess neuromuscular and corticospinal function, respectively. Exercise time was 11.4 ± 2.6 min. Peak Tc was higher in the hot compared with control (38.36 ± 0.43 °C vs 37.86 ± 0.36 °C; P = 0.035). Post-exercise reductions in maximal voluntary contraction force (13 ± 9% vs 9 ± 5%), potentiated twitch force (16 ± 12% vs 21 ± 13%) and voluntary activation (9 ± 7% vs 7 ± 7%) were similar in hot and control trials, respectively. However, cortical voluntary activation declined more in the hot compared with the control (8 ± 3% vs 3 ± 2%; P = 0.001). Exercise-induced hyperthermia elicits significant central fatigue of which a large portion can be attributed to supraspinal fatigue. These data indicate that performance decrements in the heat might initially originate in the brain.

Recent research has examined the effect that undertaking a cognitively fatiguing task for ≤90 min has on subsequent physical performance. Cognitive fatigue is claimed to affect subsequent physical performance by inducing energy depletion in the brain, depletion of brain catecholamine neurotransmitters or changes in motivation. Observation of the psychophysiology and neurochemistry literature questions the ability of 90 min' cognitive activity to deplete energy or catecholamine resources. The purpose of this study, therefore, was to examine the evidence for cognitive fatigue having an effect on subsequent physical performance. A systematic, meta-analytic review was undertaken. We found a small but significant pooled effect size based on comparison between physical performance post-cognitive fatigue compared to post-control (g = -0.27, SE = -0.12, 95% CI -0.49 to -0.04, Z(10) = -2.283, p 0.10, Τ 0.05). Thus, the results are somewhat contradictory. The pooled effect size shows a small but significant negative effect of cognitive fatigue, however tests of heterogeneity show that the results are due to random error. Future research should use neuroscientific tests to ensure that cognitive fatigue has been achieved. [Abstract copyright: Copyright © 2018 Elsevier Inc. All rights reserved.]

An initial bout of eccentric exercise is known to protect against muscle damage following a repeated bout of the same exercise, however, the neuromuscular adaptions owing to this phenomenon are unknown. \ud \ud Aim: To determine if neuromuscular disturbances are modulated following a repeated bout of eccentric exercise. \ud \ud Methods: Following eccentric exercise performed with the elbow-flexors, we measured maximal voluntary force, resting twitch force, muscle soreness, creatine kinase and voluntary activation using motor point and motor cortex stimulation at baseline, immediately post and at 1, 2, 3, 4 and 7 days post-exercise on two occasions, separated by 3 weeks. \ud \ud Results: Significant muscle damage and fatigue was evident following the first exercise bout; maximal voluntary contraction was reduced immediately by 32% and remained depressed at 7 days post-exercise. Soreness and creatine kinase release peaked at 3 and 4 days post-exercise, respectively. Resting twitch force remained significantly reduced at 7 days (−48%) whilst voluntary activation measured with motor point and motor cortex stimulation was reduced until 2 and 3 days, respectively. A repeated bout effect was observed with attenuated soreness and creatine kinase release and a quicker recovery of maximal voluntary contraction and resting twitch force. A similar decrement in voluntary activation was observed following both bouts; however, following the repeated bout there was a significantly smaller reduction in, and a faster recovery of voluntary activation measured using motor cortical stimulation. \ud \ud Conclusion: Our data suggest that the repeated bout effect may be explained, partly, by a modification in motor corticospinal drive.

Introduction - Accidental cold-water immersion (CWI) triggers the life-threatening cold shock response (CSR) which is a precursor to sudden death on immersion. One practical means of reducing the CSR is to induce an habituation by undergoing repeated short CWIs. Habituation of the CSR is known to be partially reversed by the concomitant experience of acute anxiety, raising the possibility that repeated anxiety could prevent CSR habituation; we tested this hypothesis.Method - Sixteen participants (12 male, 4 female) completed seven, seven-minute immersions in to cold water (15 °C). Immersion one acted as a control (CON1). During immersions two to five, which would ordinarily induce an habituation, anxiety levels were repeatedly increased (CWI-ANXrep) by deception and a demanding mathematical task. Immersions six and seven were counter-balanced with another high anxiety condition (CWI-ANXrep) or a further control (CON2). Anxiety (20 cm visual analogue scale) and cardiorespiratory responses (cardiac frequency [fc], respiratory frequency [fR], tidal volume [VT], minute ventilation []) were measured. Comparisons were made between experimental immersions (CON1, final CWI-ANXrep, CON2), across habituation immersions and with data from a previous study.Results - Anxiety levels were sustained at a similar level throughout the experimental and habituation immersions (mean [SD] CON1: 7.0 [4.0] cm; CON2: 5.8 [5.2] cm cf CWI-ANXrep: 7.3 [5.5] cm; p > 0.05). This culminated in failure of the CSR to habituate even when anxiety levels were not manipulated (i.e. CON2). These data were different (p < 0.05) to previous studies where anxiety levels were allowed to fall across habituation immersions and the CSR consequently habituated.Discussion - Repeated anxiety prevented CSR habituation. A protective strategy that includes inducing habituation for those at risk should include techniques to lower anxiety associated with the immersion event or habituation may not be beneficial in the emergency scenario.

Introduction: Accidental immersion in cold water is an occupational risk. Work suits and life jackets (LJ) should work effectively in combination to keep the airway clear of the water (freeboard) and enable self-righting. We hypothesized that inherent buoyancy, in the suit or LJ, would be beneficial for enabling freeboard, but its distribution may influence LJ self-righting. Methods: Six participants consented to complete nine immersions. Suits and LJ tested were: flotation suit (FLOAT; 85 N inherent buoyancy); oilskins 1 (OS-1) and 2 (OS-2), both with no inherent buoyancy; LJs (inherent buoyancy/buoyancy after inflation/total buoyancy), LJ-1 50/150/200 N, LJ-2 0/290/290 N, LJ-3 80/190/270 N. Once dressed, the subject entered an immersion pool where uninflated freeboard, self-righting performance, and inflated freeboard were measured. Data were compared using Friedman’s test to the 0.05 alpha level. Results: All suits and LJs enabled uninflated and inflated freeboard, but differences were seen between the suits and LJs. Self-righting was achieved on 43 of 54 occasions, irrespective of suit or LJ. On all occasions that self-righting was not achieved, this occurred in an LJ that included inherent buoyancy (11/54 occasions). Of these 11 failures, 8 occurred (73% of occasions) when the FLOAT suit was being worn. Discussion: LJs that included inherent buoyancy, that are certified as effective on their own, worked less effectively from the perspective of self-righting in combination with a work suit that also included inherent buoyancy. Equipment that is approved for use in the workplace should be tested in combination to ensure adequate performance in an emergency scenario.

This study aimed to examine thermoregulation in different clothing assemblies during a representative cycling exercise protocol. Six men undertook cycling exercise simulating representative thermal exchange challenges while wearing low (LOW), intermediate (INT1 and INT2), or high (HI) amounts of clothing. Exercise was conducted at 14.5 °C, 46.8% relative humidity and included a “flat” [45 min at 35% peak power output (PPO), wind speed 8.3 m/s], “uphill” (30 min at 55% PPO, wind speed 3.6 m/s), and “downhill” (20 min at 50 W, wind speed 16.7 m/s) stage. Rectal temperature changed with the exercise stage and was independent of clothing assembly. In contrast, an “envelope” was evident for mean body temperature, resulting from differences in mean skin temperature between the LOW and HI conditions. The elevated mean body temperature in HI was associated with increased physiological “cost,” in the form of increased sweat production and heart rate. Physiological cost provides a better index of clothing performance than deep body temperature in the “thermoregulatory zone,” as a consequence sports clothing should attempt to optimize the balance between comfort and reduced physiological cost.

A systematic meta-regression analysis of the effects of acute hypoxia on the performance of central executive and non-executive tasks, and the effects of the moderating variables, arterial partial pressure of oxygen (PaO2) and hypobaric versus normobaric hypoxia, was undertaken. Studies were included if they were performed on healthy humans; within-subject design was used; data were reported giving the PaO2 or that allowed the PaO2 to be estimated (e.g. arterial oxygen saturation and/or altitude); and the duration of being in a hypoxic state prior to cognitive testing was ≤6 days. Twenty-two experiments met the criteria for inclusion and demonstrated a moderate, negative mean effect size (g = −0.49, 95% CI −0.64 to −0.34, p < 0.001). There were no significant differences between central executive and non-executive, perception/attention and short-term memory, tasks. Low (35–60 mmHg) PaO2 was the key predictor of cognitive performance (R2 = 0.45, p < 0.001) and this was independent of whether the exposure was in hypobaric hypoxic or normobaric hypoxic conditions.

BACKGROUND: This case study documents the training, laboratory preparation, and in-race performance data from Great Britain’s top finisher in the 13th edition of the UVU North Pole Marathon. CASE REPORT: We report data from a preparatory laboratory test in simulated cold conditions (−15°C) with and without wind chill during high- and low-intensity expected ‘race pace’ running. These tests examined the adequacy of the selected clothing assembly and provided recommendations for the race. The tests established that there was no risk of hypothermia, as the clothing assembly provided too much insulation; terminal rectal temperature was 39.25°C. Skin temperature (Tsk) data revealed no impending risk of frostbite; nadir Tsk was 20.2°C at the hamstring. Oxygen consumption data revealed the self-selected high intensity was potentially not sustainable based on estimates of substrate utilization. We recommended: 1) a maximum running speed; 2) some of the clothing base layers could be removed pre-race; 3) vents and/or zips could be used to offload or retain heat; and 4) an even pacing profile should be adopted. DISCUSSION: The participant completed the race in 6:55:24 (h:mm:ss) in temperatures of −41°C. GPS data revealed a positive pacing template (i.e., marginally quicker in the first half). Neither hypothermia nor frostbite occurred. Peak pace from the laboratory tests was not consistently exceeded. Marathon performance can be undertaken in one of the world’s most inhospitable environments when careful consideration is given to clothing insulation and exercise intensity by planning for the dynamic thermal changes that may occur as the race ensues.

Aim: To investigate the effect of different water immersion (WI) treatments on recovery from intermittent shuttle running exercise in comparison to an ecologically relevant control. Methods: Forty males performed 90 minutes intermittent shuttle running, following which they were assigned to either: (1) 12-min standing WI at 12°C; (2) 12-min standing WI at 35°C; (3) 2-min seated WI at 12°C; (4) an ecologically relevant control consisting of 12 minutes walking at 5 km h−1. Muscle soreness, maximal voluntary contraction (MVC) of the knee flexors and extensors, hop distance, creatine kinase activity and myoglobin concentration were measured before exercise and in the 168 hours following the intervention. Between-group differences, time effects and interaction effects were investigated by mixed-model ANOVA. Results: The shuttle running exercise induced an increase in muscle soreness (1, 24, 48 and 72 hours post-intervention) creatine kinase activity and myoglobin concentration (post-exercise and 1, 24...

INTRODUCTION: The shortfall between breath-hold time on cold-water immersion and the time required to make an underwater escape from a helicopter provides the rationale for emergency underwater breathing systems (EUBS) for passengers flying over cold water. This study compared three types of EUBS: a compressed gas system (CG); a rebreather system (RB); and a hybrid system (H). METHODS: Each EUBS was examined during water deployment (W(dep)) and over 90 s in cool (25 degrees C) and cold water (12 degrees C) immersion to the neck (Imm) and submersion (Subm). Subjects wore standardized clothing, including dry suit. Measures included: W(dep) time, stay time (Imm and Subm), dyspnea rating, O2 and CO2 remaining in rebreather bags [H and RB (partial pressure mmHg)], and gas volume used (CG). RESULTS: Mean data show W(dep) was slowest in the H (17.7 s) compared to the RB (10.0 s) and CG (8.1 s). Stay time was greatest in the H (90.0 s) compared to the RB (68.3 s) and CG (87.0 s); stay time in CG was also greater than RB. Dyspnea ratings were greater in RB trials (6.5 cm) compared to the CG (2.4 cm) and H (1.9 cm). Across devices, stay time in cold water was shorter during submersion than immersion (85.9 s vs. 70.1 s). During submersion stay time was shorter in cold compared to cool water (12 degrees C: 62.8 s; 25 degrees C: 77.5 s). DISCUSSION: The data suggest that the CG and H devices outperformed the RB device, but the H device required longer to deploy.

Adaptation to an environmental stressor is usually studied in isolation, yet these stressors are often encountered in combination in the field, an example being cold and hypoxia at altitude. There has been a paucity of research in this area, although work with rodents indicates that habituation to repeated short cold exposures has a cross-adaptive effect during hypoxia. The present study tested the hypothesis that cross-adaptation is also possible with humans. Thirty-two male volunteers were exposed to 10 min bouts of normoxic and hypoxic ( 0.12) rest and exercise (100 W on a recumbent cycle ergometer). These were repeated after a 96 h interval, during which participants completed six, 5 min immersions in either cold (12°C, CW) or thermoneutral water (35°C, TW). Venous blood samples were taken immediately after each bout, for determination of catecholamine concentrations. A three-lead ECG was recorded throughout and the final 5 min of each bout was analysed for heart rate variability using fast fourier transformations (and displayed as log transformed data (ln)). In comparison with the first hypoxic exercise exposure, the second exposure of the CW group resulted in an increased ln high frequency (ln HF) power (P < 0.001) and reduced adrenaline (P < 0.001) and noradrenaline concentrations (P < 0.001). Adrenaline and noradrenaline concentrations were lower in the CW group during the second hypoxic exercise compared to the TW group (P = 0.042 and P = 0.003), but ln HF was not. When separated into hypoxic sensitive and hypoxic insensitive subgroups, ln HF was higher in the hypoxic sensitive CW group during the second hypoxic exercise than in any of the other subgroups. Cold habituation reduced the sympathetic response (indicated by the reduced catecholamine concentrations) and elevated the parasympathetic activity (increased ln HF power) to hypoxic exercise. These data suggest a generic autonomic cross-adaptive effect between cold habituation and exposure to acute hypoxia in humans.

Major sporting events are often held in hot and humid environmental conditions. Cooling techniques have been used to reduce the risk of heat illness following exercise. This study compared the efficacy of five cooling techniques, hand immersion (HI), whole body fanning (WBF), an air cooled garment (ACG), a liquid cooled garment (LCG) and a phase change garment (PCG), against a natural cooling control condition (CON) over two periods between and following exercise bouts in 31°C, 70%RH air. Nine males [age 22 (3) years; height 1.80 (0.04) m; mass 69.80 (7.10) kg] exercised on a treadmill at a maximal sustainable work intensity until rectal temperature (T re) reached 38.5°C following which they underwent a resting recovery (0–15 min; COOL 1). They then recommenced exercise until T re again reached 38.5°C and then undertook 30 min of cooling with (0–15 min; COOL 2A), and without face fanning (15–30 min; COOL 2B). Based on mean body temperature changes (COOL 1), WBF was most effective in extracting heat: CON 99 W; WBF: 235 W; PCG: 141 W; HI: 162 W; ACG: 101 W; LCG: 49 W) as a consequence of evaporating more sweat. Therefore, WBF represents a cheap and practical means of post-exercise cooling in hot, humid conditions in a sporting setting.

Fatigue is a predictable outcome of prolonged physical activity; yet its biological cause remains uncertain. During exercise, a polypeptide messenger molecule inter-leukin-6 (IL-6) is actively produced. Previously, it has been demonstrated that administration of recombinant IL-6 (rhIL-6) impairs 10-km run performance and heightened sensation of fatigue in trained runners. Both high carbohydrate diets and carbohydrate ingestion during prolonged exercise have a blunting effect on IL-6 levels post endurance exercise. We hypothesized that carbohydrate ingestion may improve performance during a prolonged bout of exercise as a consequence of a blunted IL-6 response. Seven recreationally trained fasted runners completed two 90-min time trials under CHO supplemented and placebo conditions in a randomized order. The study was of a double-blinded, placebo-controlled, cross-over study design. Distance covered in 90 min was significantly greater following exogenous carbohydrate ingestion compared with the placebo trial (19.13 ± 1.7 km and 18.29 ± 1.9 km, respectively, p = .0022). While post exercise IL-6 levels were significantly lower in the CHO trial compared with the placebo trial (5.3 ± 1.9 pg·mL−1 and 6.6 ± 3.0 pg·mL−1, respectively; p = .0313), this difference was considered physiologically too small to mediate the improvement in time trial performance.

Recent research has focused on developing air-ventilated garments to improve evaporative cooling in military settings. This study assessed a ventilated vest (Vest) in hot (45 degrees C), dry (10% RH) ambient conditions over 6 h of rest and exercise. It was hypothesized that the Vest would lower the thermal strain and increase the amount of exercise done by subjects.Eight healthy heat-acclimated men, wearing combat clothing, body armor, and a 19-kg load in webbing walked on a treadmill at 5 km h(-1) at a 2% incline until rectal temperature (T(rec)) reached 38.5 degrees C. They then rested until T(re) reached 38 degrees C, at which point they recommenced walking. On one occasion the subjects wore a Vest, blowing ambient air around the torso. On the second occasion subjects did not wear the vest (NoVest). Exercise/rest ratio, T(rec), skin temperature (T(sk)), sweat responses, rating of perceived exertion (RPE), and thermal comfort (TC) were measured.Subjects wearing theVest exercised for significantly longer (18%; 11 min/h) as a percentage of total exposure time, stopped exercise significantly less often [Mean (SD); NoVest: 3 (2) stops; Vest: 1 (2) stops], and maintained significantly lower skin temperature under the body armor [T(chest): NoVest 37.55 (0.51) degrees C; Vest: 35.33 (1.00) degrees C; T(back): NoVest: 36.85 (0.83) degrees C; Vest: 35.84 (0.88) degrees C]. The Vest provided 28 W of cooling during exercise and 73 W when at rest as estimated by thermometry.A ventilated vest can provide cooling, and thereby reduce thermal strain and increase exercise done in dry environmental temperatures up to 45 degrees C, without causing skin irritation and discomfort.

Strenuous, prolonged exercise increases interleukin-6 (IL-6) release. The effect of IL-6 is dependent on the availability of IL-6 receptors. Few studies have addressed the impact of exercise on IL-6 receptor levels or procalcitonin (PCT), an indicator of systemic inflammation. Changes in these molecules may give insight into cytokine-related mechanisms underlying exercise-related fatigue. Thirteen trained male subjects partook in the study. They cycled a total distance of 468 km over 6 days. Blood samples were obtained prior to and immediately following Day 1 of the study and then each morning prior to exercise. Blood samples were analysed for plasma IL-6, soluble IL-6 receptor (sIL-6R), C-reactive protein (CRP), PCT, creatine kinase (CK) and cortisol concentrations. Subjects also completed mood state questionnaires each day prior to exercise. IL-6 was elevated immediately post-exercise on Day 1 but was unchanged at rest for the duration of the event. In contrast, sIL-6R, CRP, PCT and CK concentrations were unchanged immediately post-exercise on Day 1 but were significantly elevated at rest over the duration of the event compared with pre-event baseline. sIL-6R was highly correlated to CRP. Cortisol concentrations remained unchanged at all time points. In conclusion, strenuous, prolonged exercise stimulated an acute phase response which was maintained throughout the 6-day event. sIL-6R increase is associated with CRP and may affect subjective sensations of post-exercise fatigue at rest.

The information presented in this chapter aims to provide an evidence base for practical interventions such as preparatory psychological strategies that are designed to aid persons in coping with accidental immersion and helicopter ditching. Based upon findings from recent laboratory and field-based investigations, this chapter explores the interactions between physiology, psychology, and perception in these life-threatening situations. Specifically, the roles that psychology and perception play in determining the physiological responses to accidental immersion and emergency underwater egress following a helicopter ditching are explored. Subsequently, other preparatory strategies such as cold-water habituation by repeated cold-water exposure are discussed. Particular attention is paid to recent evidence showing that psychology and perception play a key role in modulating the physiological responses that are seen even after habituation has taken place.

This study assessed whether donning a garment saturated with menthol and ethanol (M/E) can improve evaporative cooling and thermal perceptions versus water (W) or nothing (CON) during low intensity exercise and rest in warm, humid conditions often encountered in recreational/occupational settings. It was hypothesised there would be no difference in rectal (Tre) and skin (Tsk) temperature, infra-red thermal imagery of the chest/back, thermal comfort (TC) and rating of perceived exertion (RPE) between M/E, W and CON, but participants would feel cooler in M/E versus W or CON.\ud \ud Methods - Six volunteers (mean [SD] 22 [4] years, 72.4 [7.4] kg and 173.6 [3.7] cm) completed (separate days) three, 60-min tests in 30 °C, 70%rh, in a balanced order. After 15-min of seated rest participants donned a dry (CON) or 80 mL soaked (M/E, W) long sleeve shirt appropriate to their intervention. They then undertook 30-min of low intensity stepping at a rate of 12 steps/min on a 22.5 cm box, followed by 15-min of seated rest. Measurements included heart rate (HR), Tre, Tsk (chest/back/forearm), thermal imaging (back/chest), thermal sensation (TS), TC and RPE. Data were reported every fifth minute as they changed from baseline and the area under the curves were compared by condition using one-way repeated measures ANOVA, with an alpha level of 0.05.\ud \ud Results - Tre differed by condition, with the largest heat storage response observed in M/E (p

Many immersion suit standards require testing of thermal protective properties in calm, circulating water while these suits are typically used in harsher environments where they often underperform. Yet it can be expensive and logistically challenging to test immersion suits in realistic conditions. The goal of this work was to develop a set of correction factors that would allow suits to be tested in calm water yet ensure they will offer sufficient protection in harsher conditions. Two immersion studies, one dry and the other with 500 mL of water within the suit, were conducted in wind and waves to measure the change in suit insulation. In both studies, wind and waves resulted in a significantly lower immersed insulation value compared to calm water. The minimum required thermal insulation for maintaining heat balance can be calculated for a given mean skin temperature, metabolic heat production, and water temperature. Combining the physiological limits of sustainable cold water immersion and actual suit insulation, correction factors can be deduced for harsh conditions compared to calm. The minimum in-situ suit insulation to maintain thermal balance is 1.553–0.0624·TW + 0.00018·TW2 for a dry calm condition. Multiplicative correction factors to the above equation are 1.37, 1.25, and 1.72 for wind + waves, 500 mL suit wetness, and both combined, respectively. Calm water certification tests of suit insulation should meet or exceed the minimum in-situ requirements to maintain thermal balance, and correction factors should be applied for a more realistic determination of minimum insulation for harsh conditions.